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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
AFAFIIAE_00001	3.06e-169	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
AFAFIIAE_00002	2e-210	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
AFAFIIAE_00003	4.5e-50	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Natural resistance-associated macrophage protein
AFAFIIAE_00004	1.13e-41	-	-	-	L	-	-	-	Transposase DDE domain
AFAFIIAE_00005	2.28e-155	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
AFAFIIAE_00006	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
AFAFIIAE_00007	7.06e-117	-	-	-	-	-	-	-	-
AFAFIIAE_00008	8.65e-252	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AFAFIIAE_00009	8.7e-13	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
AFAFIIAE_00010	0.000324	-	-	-	S	-	-	-	CsbD-like
AFAFIIAE_00012	8.18e-206	-	-	-	-	-	-	-	-
AFAFIIAE_00013	3.44e-64	-	-	-	-	-	-	-	-
AFAFIIAE_00014	8.29e-74	-	-	-	-	-	-	-	-
AFAFIIAE_00015	2.87e-60	-	-	-	L	-	-	-	Protein involved in initiation of plasmid replication
AFAFIIAE_00016	0.000358	-	-	-	-	-	-	-	-
AFAFIIAE_00019	4.78e-144	-	-	-	M	-	-	-	Acyltransferase family
AFAFIIAE_00020	5.23e-123	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
AFAFIIAE_00021	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
AFAFIIAE_00022	6.37e-82	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
AFAFIIAE_00023	2.58e-37	-	-	-	-	-	-	-	-
AFAFIIAE_00024	2.37e-91	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
AFAFIIAE_00025	5.11e-93	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
AFAFIIAE_00026	8.24e-270	-	-	-	-	-	-	-	-
AFAFIIAE_00027	1.56e-36	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
AFAFIIAE_00028	3.12e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
AFAFIIAE_00029	6.84e-186	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
AFAFIIAE_00030	2.87e-157	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_00031	8.16e-43	-	-	-	-	-	-	-	-
AFAFIIAE_00032	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
AFAFIIAE_00033	1.14e-151	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
AFAFIIAE_00034	5.08e-179	-	-	-	S	-	-	-	Cell surface protein
AFAFIIAE_00035	5.11e-58	-	-	-	-	-	-	-	-
AFAFIIAE_00036	1.08e-248	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
AFAFIIAE_00037	2.64e-151	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
AFAFIIAE_00038	2.68e-75	-	-	-	-	-	-	-	-
AFAFIIAE_00039	2.02e-137	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
AFAFIIAE_00040	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
AFAFIIAE_00041	5.7e-224	yicL	-	-	EG	-	-	-	EamA-like transporter family
AFAFIIAE_00042	0.0	-	-	-	-	-	-	-	-
AFAFIIAE_00043	3.03e-186	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_00044	1.31e-67	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
AFAFIIAE_00045	5.45e-31	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
AFAFIIAE_00046	1.83e-192	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
AFAFIIAE_00047	7.88e-211	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
AFAFIIAE_00048	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AFAFIIAE_00049	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_00050	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_00051	3.34e-286	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
AFAFIIAE_00052	5.43e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
AFAFIIAE_00053	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
AFAFIIAE_00054	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
AFAFIIAE_00055	1.24e-282	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AFAFIIAE_00056	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
AFAFIIAE_00057	1.13e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
AFAFIIAE_00058	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
AFAFIIAE_00059	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
AFAFIIAE_00060	2.1e-89	-	-	-	-	-	-	-	-
AFAFIIAE_00061	1.37e-99	-	-	-	O	-	-	-	OsmC-like protein
AFAFIIAE_00062	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
AFAFIIAE_00063	7.82e-147	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
AFAFIIAE_00064	9.12e-201	-	-	-	S	-	-	-	Aldo/keto reductase family
AFAFIIAE_00065	9.04e-317	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
AFAFIIAE_00066	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
AFAFIIAE_00067	4.43e-146	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
AFAFIIAE_00068	6.4e-269	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
AFAFIIAE_00069	5.49e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
AFAFIIAE_00070	1.2e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
AFAFIIAE_00071	4.43e-191	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
AFAFIIAE_00072	2.25e-209	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_00073	6.05e-76	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
AFAFIIAE_00074	4.26e-76	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
AFAFIIAE_00075	2.71e-159	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
AFAFIIAE_00076	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
AFAFIIAE_00077	2.92e-203	-	-	-	C	-	-	-	nadph quinone reductase
AFAFIIAE_00078	2.09e-315	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
AFAFIIAE_00079	9.75e-228	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
AFAFIIAE_00080	2.22e-154	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
AFAFIIAE_00081	6.52e-153	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
AFAFIIAE_00082	5.67e-21	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
AFAFIIAE_00083	3.71e-113	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
AFAFIIAE_00084	3.29e-234	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
AFAFIIAE_00085	1.64e-200	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFAFIIAE_00086	2.24e-87	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
AFAFIIAE_00087	1.9e-18	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
AFAFIIAE_00089	9.09e-18	azoB	-	-	GM	-	-	-	NmrA family
AFAFIIAE_00090	1.85e-97	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
AFAFIIAE_00091	3.83e-201	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
AFAFIIAE_00093	6.7e-315	xylP	-	-	G	-	-	-	MFS/sugar transport protein
AFAFIIAE_00094	1.28e-96	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
AFAFIIAE_00095	1.59e-191	-	-	-	S	-	-	-	Putative transposase
AFAFIIAE_00096	6.92e-242	ysdE	-	-	P	-	-	-	Citrate transporter
AFAFIIAE_00097	1.64e-283	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
AFAFIIAE_00098	4.56e-214	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
AFAFIIAE_00099	1.34e-130	-	-	-	-	-	-	-	-
AFAFIIAE_00100	4.37e-240	yddH	-	-	M	-	-	-	NlpC/P60 family
AFAFIIAE_00101	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
AFAFIIAE_00102	0.0	-	-	-	S	-	-	-	AAA-like domain
AFAFIIAE_00103	1.4e-90	-	-	-	S	-	-	-	TcpE family
AFAFIIAE_00104	1.66e-116	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
AFAFIIAE_00105	1.84e-41	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
AFAFIIAE_00106	1.87e-107	-	-	-	L	-	-	-	DNA methylase
AFAFIIAE_00107	6.4e-72	-	-	-	-	-	-	-	-
AFAFIIAE_00108	2.82e-292	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
AFAFIIAE_00112	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
AFAFIIAE_00117	9.96e-82	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
AFAFIIAE_00118	9.87e-70	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
AFAFIIAE_00120	0.0	-	-	-	M	-	-	-	domain protein
AFAFIIAE_00121	0.0	-	-	-	M	-	-	-	domain protein
AFAFIIAE_00122	2.29e-87	-	-	-	-	-	-	-	-
AFAFIIAE_00123	4.33e-162	-	-	-	-	-	-	-	-
AFAFIIAE_00124	1.25e-158	-	-	-	S	-	-	-	Tetratricopeptide repeat
AFAFIIAE_00125	1.7e-187	-	-	-	-	-	-	-	-
AFAFIIAE_00126	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AFAFIIAE_00128	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AFAFIIAE_00129	2.63e-82	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AFAFIIAE_00130	4.64e-277	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFAFIIAE_00131	4.66e-44	-	-	-	-	-	-	-	-
AFAFIIAE_00132	5.68e-83	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
AFAFIIAE_00133	1.63e-111	queT	-	-	S	-	-	-	QueT transporter
AFAFIIAE_00134	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
AFAFIIAE_00135	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
AFAFIIAE_00137	1.9e-165	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
AFAFIIAE_00138	1.34e-154	-	-	-	S	-	-	-	(CBS) domain
AFAFIIAE_00139	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
AFAFIIAE_00140	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
AFAFIIAE_00141	1.74e-130	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AFAFIIAE_00142	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AFAFIIAE_00143	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
AFAFIIAE_00144	1.99e-53	yabO	-	-	J	-	-	-	S4 domain protein
AFAFIIAE_00145	2.92e-86	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
AFAFIIAE_00146	1.17e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
AFAFIIAE_00147	6.04e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AFAFIIAE_00148	1.14e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
AFAFIIAE_00149	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFAFIIAE_00150	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
AFAFIIAE_00151	3.37e-250	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
AFAFIIAE_00152	1.01e-79	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
AFAFIIAE_00153	7.86e-130	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
AFAFIIAE_00154	1.52e-208	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
AFAFIIAE_00155	2e-206	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AFAFIIAE_00156	3.08e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFAFIIAE_00157	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
AFAFIIAE_00158	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
AFAFIIAE_00159	8.44e-199	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
AFAFIIAE_00160	5.93e-204	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_00161	4.39e-35	-	-	-	-	-	-	-	-
AFAFIIAE_00162	2.11e-256	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
AFAFIIAE_00163	1.42e-52	-	-	-	V	-	-	-	ABC transporter transmembrane region
AFAFIIAE_00164	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
AFAFIIAE_00165	2.95e-201	is18	-	-	L	-	-	-	Integrase core domain
AFAFIIAE_00167	1.28e-132	-	-	-	-	-	-	-	-
AFAFIIAE_00168	4.9e-98	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
AFAFIIAE_00169	6.66e-19	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
AFAFIIAE_00171	7.28e-25	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
AFAFIIAE_00172	2.22e-170	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
AFAFIIAE_00173	1.29e-187	-	-	-	V	-	-	-	efflux transmembrane transporter activity
AFAFIIAE_00174	1.16e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
AFAFIIAE_00175	1.15e-132	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
AFAFIIAE_00176	7.19e-157	-	-	-	S	ko:K06872	-	ko00000	TPM domain
AFAFIIAE_00177	2.27e-305	dinF	-	-	V	-	-	-	MatE
AFAFIIAE_00178	2.76e-120	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
AFAFIIAE_00179	6.93e-197	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
AFAFIIAE_00180	1.74e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
AFAFIIAE_00181	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
AFAFIIAE_00182	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AFAFIIAE_00183	2.57e-223	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
AFAFIIAE_00184	5.77e-204	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
AFAFIIAE_00185	4.7e-50	-	-	-	-	-	-	-	-
AFAFIIAE_00186	3.21e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
AFAFIIAE_00187	3.77e-218	-	-	-	-	-	-	-	-
AFAFIIAE_00188	6.41e-24	-	-	-	-	-	-	-	-
AFAFIIAE_00189	8.06e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
AFAFIIAE_00190	9.14e-139	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
AFAFIIAE_00191	3.11e-218	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
AFAFIIAE_00192	7.41e-117	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
AFAFIIAE_00193	9.84e-195	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
AFAFIIAE_00194	4.11e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
AFAFIIAE_00195	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFAFIIAE_00196	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
AFAFIIAE_00197	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
AFAFIIAE_00198	1.18e-198	-	-	-	T	-	-	-	GHKL domain
AFAFIIAE_00199	1.67e-159	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
AFAFIIAE_00200	1.22e-220	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
AFAFIIAE_00201	1.35e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
AFAFIIAE_00202	3e-103	manR	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
AFAFIIAE_00203	7.48e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
AFAFIIAE_00204	7.92e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AFAFIIAE_00205	2.04e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AFAFIIAE_00206	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
AFAFIIAE_00207	6.63e-232	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AFAFIIAE_00208	1.99e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
AFAFIIAE_00209	1.38e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
AFAFIIAE_00210	1.84e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_00211	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
AFAFIIAE_00212	7.27e-286	ysaA	-	-	V	-	-	-	RDD family
AFAFIIAE_00213	5.45e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AFAFIIAE_00214	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFAFIIAE_00215	1.54e-73	nudA	-	-	S	-	-	-	ASCH
AFAFIIAE_00216	2.67e-244	-	-	-	E	-	-	-	glutamate:sodium symporter activity
AFAFIIAE_00217	1.03e-189	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
AFAFIIAE_00218	1.51e-262	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
AFAFIIAE_00219	1.31e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AFAFIIAE_00220	2.14e-237	-	-	-	S	-	-	-	DUF218 domain
AFAFIIAE_00221	1.41e-103	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
AFAFIIAE_00222	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
AFAFIIAE_00223	2.32e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
AFAFIIAE_00224	3.48e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
AFAFIIAE_00225	1.15e-111	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AFAFIIAE_00226	3.42e-202	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
AFAFIIAE_00227	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AFAFIIAE_00228	9.48e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFAFIIAE_00229	6.55e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
AFAFIIAE_00230	2.07e-299	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AFAFIIAE_00232	5.8e-83	-	-	-	-	-	-	-	-
AFAFIIAE_00233	8.36e-88	tnp	-	-	-	ko:K07498	-	ko00000	-
AFAFIIAE_00234	4.97e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
AFAFIIAE_00235	1.1e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AFAFIIAE_00236	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
AFAFIIAE_00237	2.57e-67	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
AFAFIIAE_00238	5.99e-243	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AFAFIIAE_00239	8.44e-130	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
AFAFIIAE_00240	3.82e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
AFAFIIAE_00241	3.98e-94	-	-	-	-	-	-	-	-
AFAFIIAE_00242	2.42e-117	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
AFAFIIAE_00243	6.13e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
AFAFIIAE_00244	3.86e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
AFAFIIAE_00245	6.07e-192	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AFAFIIAE_00246	7.92e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
AFAFIIAE_00247	6.53e-223	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
AFAFIIAE_00248	1.14e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
AFAFIIAE_00249	9.81e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AFAFIIAE_00250	2.95e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
AFAFIIAE_00251	1.26e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AFAFIIAE_00252	7e-49	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AFAFIIAE_00253	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFAFIIAE_00254	4.38e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AFAFIIAE_00255	9.05e-67	-	-	-	-	-	-	-	-
AFAFIIAE_00256	2.74e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
AFAFIIAE_00257	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AFAFIIAE_00258	4.68e-59	-	-	-	-	-	-	-	-
AFAFIIAE_00259	3.52e-224	ccpB	-	-	K	-	-	-	lacI family
AFAFIIAE_00260	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
AFAFIIAE_00261	7.22e-207	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AFAFIIAE_00262	1.37e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AFAFIIAE_00263	7.23e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AFAFIIAE_00264	1.92e-283	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
AFAFIIAE_00265	8.22e-198	-	-	-	K	-	-	-	acetyltransferase
AFAFIIAE_00266	4.02e-86	-	-	-	-	-	-	-	-
AFAFIIAE_00267	1.19e-277	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
AFAFIIAE_00268	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
AFAFIIAE_00269	1.89e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AFAFIIAE_00270	6.87e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AFAFIIAE_00271	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
AFAFIIAE_00272	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
AFAFIIAE_00273	1.66e-84	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
AFAFIIAE_00274	8.78e-120	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
AFAFIIAE_00275	7.87e-125	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
AFAFIIAE_00276	4.31e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
AFAFIIAE_00277	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
AFAFIIAE_00278	3.77e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
AFAFIIAE_00279	1.71e-205	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
AFAFIIAE_00280	2.29e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
AFAFIIAE_00281	2.09e-30	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AFAFIIAE_00282	2.54e-217	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
AFAFIIAE_00283	2.34e-214	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
AFAFIIAE_00284	2.2e-252	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AFAFIIAE_00285	6.86e-187	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
AFAFIIAE_00286	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
AFAFIIAE_00287	2.27e-103	-	-	-	S	-	-	-	NusG domain II
AFAFIIAE_00288	1.03e-127	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
AFAFIIAE_00289	1.05e-228	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
AFAFIIAE_00291	2.3e-158	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
AFAFIIAE_00292	1.22e-247	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
AFAFIIAE_00293	1.55e-169	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
AFAFIIAE_00294	4.06e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
AFAFIIAE_00295	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
AFAFIIAE_00296	1.56e-230	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	carboxylic ester hydrolase activity
AFAFIIAE_00297	1.69e-58	-	-	-	-	-	-	-	-
AFAFIIAE_00298	4.89e-122	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AFAFIIAE_00299	3.96e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AFAFIIAE_00300	7.46e-157	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
AFAFIIAE_00301	6.42e-101	-	-	-	K	-	-	-	Transcriptional regulator
AFAFIIAE_00302	2.81e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
AFAFIIAE_00303	3.83e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
AFAFIIAE_00304	2.94e-198	dkgB	-	-	S	-	-	-	reductase
AFAFIIAE_00305	6.77e-201	-	-	-	-	-	-	-	-
AFAFIIAE_00306	6.16e-199	-	-	-	S	-	-	-	Alpha beta hydrolase
AFAFIIAE_00307	7.76e-152	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
AFAFIIAE_00308	4.49e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
AFAFIIAE_00310	4.87e-283	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
AFAFIIAE_00311	1.69e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AFAFIIAE_00312	1.3e-136	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
AFAFIIAE_00313	2.95e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AFAFIIAE_00314	1.59e-241	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AFAFIIAE_00315	4.54e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AFAFIIAE_00316	3.46e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AFAFIIAE_00317	2.6e-87	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
AFAFIIAE_00318	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
AFAFIIAE_00319	2.06e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
AFAFIIAE_00320	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AFAFIIAE_00321	7.25e-264	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFAFIIAE_00322	1.13e-307	ytoI	-	-	K	-	-	-	DRTGG domain
AFAFIIAE_00323	3.03e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
AFAFIIAE_00324	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AFAFIIAE_00325	1.55e-223	-	-	-	-	-	-	-	-
AFAFIIAE_00326	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AFAFIIAE_00328	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
AFAFIIAE_00329	2.67e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AFAFIIAE_00330	1.3e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
AFAFIIAE_00331	2.84e-48	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AFAFIIAE_00332	1.89e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
AFAFIIAE_00333	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AFAFIIAE_00334	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
AFAFIIAE_00335	1.04e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
AFAFIIAE_00336	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFAFIIAE_00337	9.86e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
AFAFIIAE_00338	6.97e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFAFIIAE_00339	8.29e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AFAFIIAE_00340	6.77e-111	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
AFAFIIAE_00341	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
AFAFIIAE_00342	4.7e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
AFAFIIAE_00343	5.44e-175	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
AFAFIIAE_00344	9.32e-112	ykuL	-	-	S	-	-	-	CBS domain
AFAFIIAE_00345	4.63e-199	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
AFAFIIAE_00346	6.86e-198	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
AFAFIIAE_00347	1.49e-46	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AFAFIIAE_00348	4.84e-114	ytxH	-	-	S	-	-	-	YtxH-like protein
AFAFIIAE_00349	7.49e-117	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
AFAFIIAE_00350	1.8e-273	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
AFAFIIAE_00351	3.03e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
AFAFIIAE_00352	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
AFAFIIAE_00353	9.88e-08	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
AFAFIIAE_00354	6.75e-256	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
AFAFIIAE_00355	8.86e-62	-	-	-	S	-	-	-	Thiamine-binding protein
AFAFIIAE_00356	6.39e-177	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
AFAFIIAE_00357	1.58e-202	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
AFAFIIAE_00358	1.77e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFAFIIAE_00359	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
AFAFIIAE_00360	1.1e-76	-	-	-	-	-	-	-	-
AFAFIIAE_00361	3.07e-218	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
AFAFIIAE_00362	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
AFAFIIAE_00364	1.99e-241	ynjC	-	-	S	-	-	-	Cell surface protein
AFAFIIAE_00365	2.04e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
AFAFIIAE_00366	2e-167	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
AFAFIIAE_00368	0.0	-	-	-	-	-	-	-	-
AFAFIIAE_00369	4.96e-133	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AFAFIIAE_00370	6.64e-39	-	-	-	-	-	-	-	-
AFAFIIAE_00371	3.71e-63	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFAFIIAE_00372	5.98e-103	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFAFIIAE_00374	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
AFAFIIAE_00375	2.42e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
AFAFIIAE_00376	1.55e-70	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
AFAFIIAE_00377	5.79e-207	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	alcohol dehydrogenase
AFAFIIAE_00378	6.94e-106	-	-	-	K	-	-	-	Transcriptional regulator
AFAFIIAE_00379	6.75e-57	-	-	-	-	-	-	-	-
AFAFIIAE_00380	1.17e-245	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFAFIIAE_00381	1.37e-114	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
AFAFIIAE_00382	2.61e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
AFAFIIAE_00383	6.55e-57	-	-	-	-	-	-	-	-
AFAFIIAE_00384	5.31e-266	mccF	-	-	V	-	-	-	LD-carboxypeptidase
AFAFIIAE_00385	3.17e-235	yveB	-	-	I	-	-	-	PAP2 superfamily
AFAFIIAE_00386	7.64e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
AFAFIIAE_00387	1.06e-49	-	-	-	-	-	-	-	-
AFAFIIAE_00388	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
AFAFIIAE_00389	1.29e-182	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
AFAFIIAE_00390	0.0	-	-	-	-	-	-	-	-
AFAFIIAE_00391	1.75e-127	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
AFAFIIAE_00393	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
AFAFIIAE_00394	3.78e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
AFAFIIAE_00395	1.71e-212	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_00396	1.91e-46	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
AFAFIIAE_00397	1.84e-260	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AFAFIIAE_00398	2.43e-206	lysR5	-	-	K	-	-	-	LysR substrate binding domain
AFAFIIAE_00399	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
AFAFIIAE_00400	4.34e-75	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
AFAFIIAE_00401	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
AFAFIIAE_00402	9.64e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AFAFIIAE_00403	1.42e-153	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
AFAFIIAE_00404	1.01e-165	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AFAFIIAE_00405	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
AFAFIIAE_00406	1.28e-274	-	-	-	-	-	-	-	-
AFAFIIAE_00407	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
AFAFIIAE_00408	1.58e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
AFAFIIAE_00409	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
AFAFIIAE_00410	1.18e-37	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_00411	5.31e-70	-	-	-	-	-	-	-	-
AFAFIIAE_00412	7.17e-143	-	-	-	-	-	-	-	-
AFAFIIAE_00413	5.69e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
AFAFIIAE_00414	3.02e-170	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_00415	4.22e-133	XK27_06945	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
AFAFIIAE_00416	1.87e-173	XK27_06950	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
AFAFIIAE_00417	2.8e-190	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_00418	1.17e-154	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
AFAFIIAE_00419	3.69e-297	-	-	-	I	-	-	-	Acyltransferase family
AFAFIIAE_00420	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
AFAFIIAE_00421	5.18e-224	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
AFAFIIAE_00422	1.97e-188	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_00423	1e-173	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_00424	1.49e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AFAFIIAE_00425	1.64e-211	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
AFAFIIAE_00427	5.31e-90	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFAFIIAE_00428	7.18e-68	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFAFIIAE_00432	1.55e-94	-	-	-	-	-	-	-	-
AFAFIIAE_00433	2.1e-27	-	-	-	-	-	-	-	-
AFAFIIAE_00434	2.09e-211	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
AFAFIIAE_00435	1.38e-284	-	-	-	M	-	-	-	domain protein
AFAFIIAE_00436	2.87e-101	-	-	-	-	-	-	-	-
AFAFIIAE_00437	1.91e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
AFAFIIAE_00438	4.69e-151	-	-	-	GM	-	-	-	NmrA-like family
AFAFIIAE_00439	5.54e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
AFAFIIAE_00440	6.85e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFAFIIAE_00441	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
AFAFIIAE_00442	2.78e-169	-	3.6.3.35	-	P	ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
AFAFIIAE_00443	1.69e-184	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
AFAFIIAE_00444	1.09e-224	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
AFAFIIAE_00445	7.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
AFAFIIAE_00446	7.75e-145	-	-	-	P	-	-	-	Cation efflux family
AFAFIIAE_00447	1.53e-35	-	-	-	-	-	-	-	-
AFAFIIAE_00448	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
AFAFIIAE_00449	5.15e-305	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
AFAFIIAE_00450	1.14e-72	-	-	-	-	-	-	-	-
AFAFIIAE_00451	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
AFAFIIAE_00452	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
AFAFIIAE_00453	6.42e-28	-	-	-	-	-	-	-	-
AFAFIIAE_00454	6.05e-171	-	-	-	-	-	-	-	-
AFAFIIAE_00455	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AFAFIIAE_00456	8.62e-273	yqiG	-	-	C	-	-	-	Oxidoreductase
AFAFIIAE_00457	2.03e-165	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
AFAFIIAE_00458	5.65e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
AFAFIIAE_00459	6.03e-17	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
AFAFIIAE_00460	1.41e-06	-	-	-	S	-	-	-	SpoVT / AbrB like domain
AFAFIIAE_00461	8.67e-34	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
AFAFIIAE_00462	3.96e-60	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
AFAFIIAE_00463	4.33e-70	-	-	-	S	-	-	-	Enterocin A Immunity
AFAFIIAE_00464	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
AFAFIIAE_00465	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
AFAFIIAE_00466	3.69e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
AFAFIIAE_00467	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
AFAFIIAE_00468	3.47e-210	-	-	-	GM	-	-	-	NmrA-like family
AFAFIIAE_00469	3.95e-297	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
AFAFIIAE_00470	3.41e-184	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
AFAFIIAE_00471	3.05e-194	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AFAFIIAE_00472	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
AFAFIIAE_00473	3.23e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AFAFIIAE_00474	8.8e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AFAFIIAE_00475	6.98e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFAFIIAE_00476	3.37e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
AFAFIIAE_00477	3.44e-209	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
AFAFIIAE_00478	4.56e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
AFAFIIAE_00479	1.38e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFAFIIAE_00480	3.96e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFAFIIAE_00481	2.44e-99	-	-	-	K	-	-	-	Winged helix DNA-binding domain
AFAFIIAE_00482	6.79e-95	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
AFAFIIAE_00484	9.95e-244	-	-	-	E	-	-	-	Alpha/beta hydrolase family
AFAFIIAE_00485	5.34e-288	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
AFAFIIAE_00486	3.45e-64	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
AFAFIIAE_00487	2.84e-88	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
AFAFIIAE_00488	5.76e-14	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
AFAFIIAE_00489	3.56e-216	-	-	-	S	-	-	-	Putative esterase
AFAFIIAE_00490	1.83e-256	-	-	-	-	-	-	-	-
AFAFIIAE_00491	1.47e-136	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
AFAFIIAE_00492	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
AFAFIIAE_00493	2.69e-105	-	-	-	F	-	-	-	NUDIX domain
AFAFIIAE_00494	4.68e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AFAFIIAE_00495	4.74e-30	-	-	-	-	-	-	-	-
AFAFIIAE_00496	8.98e-209	-	-	-	S	-	-	-	zinc-ribbon domain
AFAFIIAE_00497	2.41e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
AFAFIIAE_00498	4.01e-240	ydbI	-	-	K	-	-	-	AI-2E family transporter
AFAFIIAE_00499	4.31e-166	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
AFAFIIAE_00500	2.33e-84	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
AFAFIIAE_00501	3.52e-224	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
AFAFIIAE_00502	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
AFAFIIAE_00503	3.51e-216	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
AFAFIIAE_00504	5.82e-189	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
AFAFIIAE_00505	9.19e-285	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
AFAFIIAE_00506	3.99e-176	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
AFAFIIAE_00507	6.13e-95	usp1	-	-	T	-	-	-	Universal stress protein family
AFAFIIAE_00508	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
AFAFIIAE_00509	6.35e-195	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AFAFIIAE_00510	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
AFAFIIAE_00511	6.52e-290	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
AFAFIIAE_00512	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
AFAFIIAE_00513	2.07e-43	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
AFAFIIAE_00514	2.7e-176	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AFAFIIAE_00515	9.32e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFAFIIAE_00516	1.92e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFAFIIAE_00517	1.15e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFAFIIAE_00518	1.13e-147	-	-	-	-	-	-	-	-
AFAFIIAE_00519	5.46e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
AFAFIIAE_00520	1.26e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFAFIIAE_00521	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AFAFIIAE_00522	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFAFIIAE_00523	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
AFAFIIAE_00524	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AFAFIIAE_00525	1.29e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AFAFIIAE_00526	2.01e-303	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AFAFIIAE_00527	4.07e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
AFAFIIAE_00528	2.6e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
AFAFIIAE_00529	5.74e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AFAFIIAE_00530	1.62e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AFAFIIAE_00531	2.61e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AFAFIIAE_00532	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AFAFIIAE_00533	8.67e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFAFIIAE_00534	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AFAFIIAE_00535	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AFAFIIAE_00536	5.93e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AFAFIIAE_00537	3.55e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
AFAFIIAE_00538	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AFAFIIAE_00539	6.88e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AFAFIIAE_00540	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AFAFIIAE_00541	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AFAFIIAE_00542	7.23e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFAFIIAE_00543	1.02e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AFAFIIAE_00544	1.98e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
AFAFIIAE_00545	4.01e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AFAFIIAE_00546	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
AFAFIIAE_00547	3.63e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
AFAFIIAE_00548	1.38e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
AFAFIIAE_00549	1.89e-254	-	-	-	K	-	-	-	WYL domain
AFAFIIAE_00550	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AFAFIIAE_00551	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AFAFIIAE_00552	1.11e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AFAFIIAE_00553	5.32e-220	-	-	-	M	-	-	-	domain protein
AFAFIIAE_00554	0.0	-	-	-	M	-	-	-	domain protein
AFAFIIAE_00555	1.81e-47	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
AFAFIIAE_00556	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFAFIIAE_00557	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFAFIIAE_00558	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AFAFIIAE_00559	4.32e-105	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
AFAFIIAE_00568	6.85e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
AFAFIIAE_00569	9.2e-101	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFAFIIAE_00570	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
AFAFIIAE_00571	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
AFAFIIAE_00572	2.09e-169	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AFAFIIAE_00573	2.23e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
AFAFIIAE_00574	5.93e-59	-	-	-	-	-	-	-	-
AFAFIIAE_00575	6.72e-19	-	-	-	-	-	-	-	-
AFAFIIAE_00576	1.51e-238	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFAFIIAE_00577	2.9e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_00578	4e-262	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
AFAFIIAE_00579	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
AFAFIIAE_00580	1.49e-253	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
AFAFIIAE_00581	1.47e-286	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
AFAFIIAE_00582	1.48e-104	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
AFAFIIAE_00583	2.2e-174	labL	-	-	S	-	-	-	Putative threonine/serine exporter
AFAFIIAE_00585	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AFAFIIAE_00586	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AFAFIIAE_00587	8.23e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
AFAFIIAE_00588	1.04e-177	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFAFIIAE_00589	2.99e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AFAFIIAE_00590	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
AFAFIIAE_00591	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AFAFIIAE_00592	1.02e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AFAFIIAE_00594	1.66e-42	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
AFAFIIAE_00595	9.09e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AFAFIIAE_00596	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFAFIIAE_00597	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFAFIIAE_00598	5.22e-163	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AFAFIIAE_00599	1.23e-96	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AFAFIIAE_00600	1.36e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
AFAFIIAE_00601	1.54e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AFAFIIAE_00602	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AFAFIIAE_00603	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
AFAFIIAE_00604	2.22e-226	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
AFAFIIAE_00605	8.07e-40	-	-	-	-	-	-	-	-
AFAFIIAE_00606	2.31e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
AFAFIIAE_00607	1.7e-104	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
AFAFIIAE_00608	4.15e-72	-	-	-	-	-	-	-	-
AFAFIIAE_00609	3.64e-70	-	-	-	-	-	-	-	-
AFAFIIAE_00610	2.87e-181	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
AFAFIIAE_00611	2.76e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AFAFIIAE_00612	1.38e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AFAFIIAE_00613	2.76e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
AFAFIIAE_00614	1.03e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AFAFIIAE_00615	3.27e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
AFAFIIAE_00617	1.81e-88	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
AFAFIIAE_00618	3.98e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
AFAFIIAE_00619	8.44e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AFAFIIAE_00620	1.6e-206	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AFAFIIAE_00621	3.1e-216	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFAFIIAE_00622	3.08e-107	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
AFAFIIAE_00623	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AFAFIIAE_00624	2.67e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
AFAFIIAE_00625	3.9e-48	XK27_04345	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
AFAFIIAE_00626	7.04e-217	-	-	-	C	-	-	-	nadph quinone reductase
AFAFIIAE_00627	4.23e-99	-	-	-	-	-	-	-	-
AFAFIIAE_00628	5.67e-191	-	-	-	K	-	-	-	Helix-turn-helix
AFAFIIAE_00629	0.0	-	-	-	-	-	-	-	-
AFAFIIAE_00630	3.28e-199	-	-	-	V	-	-	-	ABC transporter
AFAFIIAE_00631	6.52e-107	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
AFAFIIAE_00632	3.28e-313	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
AFAFIIAE_00633	1.35e-150	-	-	-	J	-	-	-	HAD-hyrolase-like
AFAFIIAE_00634	1.59e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AFAFIIAE_00635	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AFAFIIAE_00636	5.49e-58	-	-	-	-	-	-	-	-
AFAFIIAE_00637	3.13e-170	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AFAFIIAE_00638	6.78e-220	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
AFAFIIAE_00639	1.42e-112	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
AFAFIIAE_00640	1.68e-134	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
AFAFIIAE_00641	2.23e-50	-	-	-	-	-	-	-	-
AFAFIIAE_00642	8.05e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
AFAFIIAE_00643	6.1e-27	-	-	-	-	-	-	-	-
AFAFIIAE_00644	1.72e-64	-	-	-	-	-	-	-	-
AFAFIIAE_00645	1.79e-59	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AFAFIIAE_00648	5.15e-142	-	-	-	S	-	-	-	Flavodoxin-like fold
AFAFIIAE_00649	2.46e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AFAFIIAE_00650	6.33e-185	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
AFAFIIAE_00651	1.66e-71	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
AFAFIIAE_00652	2.86e-118	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AFAFIIAE_00653	1.7e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AFAFIIAE_00654	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
AFAFIIAE_00655	1.79e-75	-	-	-	-	-	-	-	-
AFAFIIAE_00656	5.87e-109	-	-	-	S	-	-	-	ASCH
AFAFIIAE_00657	6.27e-32	-	-	-	-	-	-	-	-
AFAFIIAE_00658	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AFAFIIAE_00659	9.45e-261	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AFAFIIAE_00660	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
AFAFIIAE_00661	3.18e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AFAFIIAE_00662	1.6e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AFAFIIAE_00663	8.81e-288	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
AFAFIIAE_00664	9.76e-229	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
AFAFIIAE_00665	2.83e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AFAFIIAE_00666	4.46e-183	terC	-	-	P	-	-	-	Integral membrane protein TerC family
AFAFIIAE_00667	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AFAFIIAE_00668	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AFAFIIAE_00669	1.29e-60	ylxQ	-	-	J	-	-	-	ribosomal protein
AFAFIIAE_00670	9.63e-61	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
AFAFIIAE_00671	4.13e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
AFAFIIAE_00672	1.33e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
AFAFIIAE_00673	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFAFIIAE_00674	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AFAFIIAE_00675	3.52e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
AFAFIIAE_00676	7.66e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
AFAFIIAE_00677	3.69e-180	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFAFIIAE_00678	1.73e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AFAFIIAE_00679	5.86e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
AFAFIIAE_00680	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AFAFIIAE_00681	1.18e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
AFAFIIAE_00682	1.88e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
AFAFIIAE_00683	1.18e-167	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
AFAFIIAE_00684	8.45e-160	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
AFAFIIAE_00685	2.56e-80	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
AFAFIIAE_00686	1.54e-187	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
AFAFIIAE_00687	4.28e-181	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
AFAFIIAE_00688	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_00689	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_00690	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
AFAFIIAE_00691	2.84e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
AFAFIIAE_00692	9.42e-28	-	-	-	-	-	-	-	-
AFAFIIAE_00693	2e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AFAFIIAE_00694	6.15e-186	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
AFAFIIAE_00695	2.16e-120	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AFAFIIAE_00696	1.55e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
AFAFIIAE_00697	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
AFAFIIAE_00698	2.16e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFAFIIAE_00699	1.26e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AFAFIIAE_00701	7.91e-70	-	-	-	-	-	-	-	-
AFAFIIAE_00702	1.5e-231	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFAFIIAE_00703	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
AFAFIIAE_00704	2.8e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AFAFIIAE_00705	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
AFAFIIAE_00706	1.8e-197	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_00707	3.2e-216	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AFAFIIAE_00708	5.65e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
AFAFIIAE_00709	4.24e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
AFAFIIAE_00710	3.21e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFAFIIAE_00711	1.41e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AFAFIIAE_00712	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AFAFIIAE_00713	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
AFAFIIAE_00714	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
AFAFIIAE_00715	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
AFAFIIAE_00716	5.28e-166	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
AFAFIIAE_00717	4.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
AFAFIIAE_00718	4.61e-220	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AFAFIIAE_00719	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
AFAFIIAE_00720	5.22e-174	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
AFAFIIAE_00721	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AFAFIIAE_00722	9.71e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AFAFIIAE_00723	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFAFIIAE_00724	1.38e-275	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AFAFIIAE_00725	1.77e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AFAFIIAE_00726	2.52e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
AFAFIIAE_00727	6.38e-115	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
AFAFIIAE_00728	1.57e-65	-	-	-	-	-	-	-	-
AFAFIIAE_00730	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
AFAFIIAE_00731	4.19e-96	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
AFAFIIAE_00732	8.09e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
AFAFIIAE_00733	3.67e-189	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
AFAFIIAE_00734	1.42e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFAFIIAE_00735	3.14e-295	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFAFIIAE_00736	1.23e-190	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AFAFIIAE_00737	6.72e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AFAFIIAE_00738	9.44e-99	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
AFAFIIAE_00739	6.06e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFAFIIAE_00740	2.92e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
AFAFIIAE_00741	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
AFAFIIAE_00742	1.77e-74	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
AFAFIIAE_00743	5.83e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
AFAFIIAE_00744	1.17e-16	-	-	-	-	-	-	-	-
AFAFIIAE_00747	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AFAFIIAE_00748	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
AFAFIIAE_00749	1.32e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
AFAFIIAE_00750	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
AFAFIIAE_00751	1.65e-304	ynbB	-	-	P	-	-	-	aluminum resistance
AFAFIIAE_00752	6.3e-222	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AFAFIIAE_00753	3.33e-35	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
AFAFIIAE_00754	1.93e-96	yqhL	-	-	P	-	-	-	Rhodanese-like protein
AFAFIIAE_00755	1.13e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
AFAFIIAE_00756	3.93e-54	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
AFAFIIAE_00757	1.33e-157	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
AFAFIIAE_00758	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
AFAFIIAE_00759	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
AFAFIIAE_00760	1.15e-71	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
AFAFIIAE_00761	2.04e-149	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
AFAFIIAE_00762	3.81e-231	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
AFAFIIAE_00763	1.1e-164	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
AFAFIIAE_00764	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFAFIIAE_00765	3.43e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
AFAFIIAE_00766	1.52e-264	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AFAFIIAE_00767	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFAFIIAE_00768	3.55e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AFAFIIAE_00769	1.2e-87	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
AFAFIIAE_00770	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
AFAFIIAE_00771	4.47e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFAFIIAE_00772	4.17e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
AFAFIIAE_00773	8.99e-229	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFAFIIAE_00774	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
AFAFIIAE_00775	1.01e-157	csrR	-	-	K	-	-	-	response regulator
AFAFIIAE_00776	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AFAFIIAE_00777	3.14e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
AFAFIIAE_00778	2.27e-268	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
AFAFIIAE_00779	8.06e-177	yccK	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
AFAFIIAE_00780	1.18e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AFAFIIAE_00781	3.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
AFAFIIAE_00782	2.72e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AFAFIIAE_00783	3.95e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
AFAFIIAE_00784	3.02e-262	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
AFAFIIAE_00785	6.63e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
AFAFIIAE_00786	2.77e-220	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFAFIIAE_00787	2.74e-243	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFAFIIAE_00788	4.31e-157	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
AFAFIIAE_00789	2.91e-229	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
AFAFIIAE_00790	8.27e-130	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
AFAFIIAE_00791	1.02e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AFAFIIAE_00792	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
AFAFIIAE_00793	7.46e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AFAFIIAE_00794	2.7e-166	-	-	-	S	-	-	-	SseB protein N-terminal domain
AFAFIIAE_00795	5.3e-70	-	-	-	-	-	-	-	-
AFAFIIAE_00796	1.17e-130	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
AFAFIIAE_00797	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFAFIIAE_00799	1.02e-180	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
AFAFIIAE_00800	1.04e-303	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
AFAFIIAE_00801	2.06e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AFAFIIAE_00802	6.38e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AFAFIIAE_00803	2.52e-203	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AFAFIIAE_00804	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AFAFIIAE_00805	2.55e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
AFAFIIAE_00806	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
AFAFIIAE_00807	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
AFAFIIAE_00808	3.17e-149	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFAFIIAE_00809	5.32e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
AFAFIIAE_00810	3.03e-06	-	-	-	S	-	-	-	Small secreted protein
AFAFIIAE_00811	1.35e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AFAFIIAE_00812	4.51e-189	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
AFAFIIAE_00813	8.32e-275	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_00814	2.4e-172	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_00815	1.67e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
AFAFIIAE_00816	5.77e-81	-	-	-	S	-	-	-	YtxH-like protein
AFAFIIAE_00817	5.26e-205	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AFAFIIAE_00818	8.42e-232	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
AFAFIIAE_00819	1.03e-72	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
AFAFIIAE_00820	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
AFAFIIAE_00821	1.3e-198	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
AFAFIIAE_00822	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
AFAFIIAE_00823	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
AFAFIIAE_00825	1.97e-88	-	-	-	-	-	-	-	-
AFAFIIAE_00826	1.16e-31	-	-	-	-	-	-	-	-
AFAFIIAE_00827	3.67e-227	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
AFAFIIAE_00828	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
AFAFIIAE_00829	1.44e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AFAFIIAE_00830	2.54e-72	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AFAFIIAE_00831	3.28e-176	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
AFAFIIAE_00832	7.88e-121	traP	1.14.99.57, 6.2.1.3	-	S	ko:K01897,ko:K21481	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	heme oxygenase (decyclizing) activity
AFAFIIAE_00833	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
AFAFIIAE_00834	1.14e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_00835	2.6e-158	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
AFAFIIAE_00836	1.58e-262	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
AFAFIIAE_00837	1.54e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AFAFIIAE_00838	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
AFAFIIAE_00839	1.17e-100	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
AFAFIIAE_00840	0.0	-	-	-	M	-	-	-	domain protein
AFAFIIAE_00841	5.57e-305	-	-	-	-	-	-	-	-
AFAFIIAE_00842	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
AFAFIIAE_00843	5.2e-188	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
AFAFIIAE_00844	1.09e-292	-	-	-	S	-	-	-	Membrane
AFAFIIAE_00845	2.57e-55	-	-	-	-	-	-	-	-
AFAFIIAE_00847	5.43e-191	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AFAFIIAE_00848	1.15e-279	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AFAFIIAE_00849	4.93e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
AFAFIIAE_00850	1.27e-23	-	-	-	-	-	-	-	-
AFAFIIAE_00851	1.5e-44	-	-	-	-	-	-	-	-
AFAFIIAE_00853	1.59e-28	yhjA	-	-	K	-	-	-	CsbD-like
AFAFIIAE_00854	2.84e-263	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
AFAFIIAE_00855	5.25e-61	-	-	-	-	-	-	-	-
AFAFIIAE_00856	4.71e-263	-	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
AFAFIIAE_00857	3.99e-157	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AFAFIIAE_00858	8.84e-120	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
AFAFIIAE_00859	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
AFAFIIAE_00860	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
AFAFIIAE_00861	1.17e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
AFAFIIAE_00862	7.42e-277	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
AFAFIIAE_00863	2.2e-253	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
AFAFIIAE_00864	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
AFAFIIAE_00865	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
AFAFIIAE_00866	2.42e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
AFAFIIAE_00867	1e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
AFAFIIAE_00868	4.85e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
AFAFIIAE_00869	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AFAFIIAE_00870	5.49e-261	yacL	-	-	S	-	-	-	domain protein
AFAFIIAE_00871	4.17e-204	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_00872	7.55e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
AFAFIIAE_00873	3.49e-288	inlJ	-	-	M	-	-	-	MucBP domain
AFAFIIAE_00874	5.31e-82	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
AFAFIIAE_00875	3.93e-226	-	-	-	S	-	-	-	Membrane
AFAFIIAE_00876	1.07e-144	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
AFAFIIAE_00877	1.73e-182	-	-	-	K	-	-	-	SIS domain
AFAFIIAE_00878	5.22e-153	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
AFAFIIAE_00879	1.91e-236	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
AFAFIIAE_00880	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFAFIIAE_00883	1.6e-161	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
AFAFIIAE_00884	2.73e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
AFAFIIAE_00885	3.19e-207	-	-	-	S	-	-	-	Alpha beta hydrolase
AFAFIIAE_00886	3.03e-233	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AFAFIIAE_00887	2.86e-161	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
AFAFIIAE_00888	0.0	-	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_00889	4.67e-146	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
AFAFIIAE_00890	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
AFAFIIAE_00891	1.59e-213	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_00892	2.58e-176	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
AFAFIIAE_00893	1.86e-183	ORF00048	-	-	-	-	-	-	-
AFAFIIAE_00894	1.13e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
AFAFIIAE_00895	3.85e-137	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
AFAFIIAE_00896	2.36e-111	-	-	-	K	-	-	-	GNAT family
AFAFIIAE_00897	1.09e-134	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AFAFIIAE_00898	3.61e-55	-	-	-	-	-	-	-	-
AFAFIIAE_00899	1.43e-307	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
AFAFIIAE_00900	2.14e-69	-	-	-	-	-	-	-	-
AFAFIIAE_00901	4.32e-60	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
AFAFIIAE_00902	1.13e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
AFAFIIAE_00903	3.26e-07	-	-	-	-	-	-	-	-
AFAFIIAE_00904	2.12e-228	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AFAFIIAE_00905	3.41e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
AFAFIIAE_00906	7.46e-201	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
AFAFIIAE_00907	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
AFAFIIAE_00908	9.61e-119	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
AFAFIIAE_00909	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
AFAFIIAE_00910	4.83e-162	citR	-	-	K	-	-	-	FCD
AFAFIIAE_00911	8.1e-199	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
AFAFIIAE_00912	7.43e-97	-	-	-	-	-	-	-	-
AFAFIIAE_00913	9.13e-41	-	-	-	-	-	-	-	-
AFAFIIAE_00914	1.25e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
AFAFIIAE_00915	5.53e-202	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
AFAFIIAE_00916	1.21e-149	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AFAFIIAE_00917	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
AFAFIIAE_00918	8.02e-114	-	-	-	-	-	-	-	-
AFAFIIAE_00919	3.08e-242	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
AFAFIIAE_00920	2.94e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
AFAFIIAE_00921	4.81e-127	-	-	-	-	-	-	-	-
AFAFIIAE_00922	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
AFAFIIAE_00923	2.4e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
AFAFIIAE_00925	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
AFAFIIAE_00926	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
AFAFIIAE_00927	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
AFAFIIAE_00928	1.81e-292	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AFAFIIAE_00929	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AFAFIIAE_00930	7.1e-111	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
AFAFIIAE_00931	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AFAFIIAE_00932	3.12e-90	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
AFAFIIAE_00933	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
AFAFIIAE_00935	1.89e-167	-	-	-	S	-	-	-	Protein of unknown function C-terminus (DUF2399)
AFAFIIAE_00936	0.0	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
AFAFIIAE_00937	3.57e-15	-	-	-	D	-	-	-	Putative exonuclease SbcCD, C subunit
AFAFIIAE_00938	5.02e-176	-	-	-	-	-	-	-	-
AFAFIIAE_00939	9.69e-285	-	-	-	-	-	-	-	-
AFAFIIAE_00940	1.83e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
AFAFIIAE_00941	1.79e-87	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
AFAFIIAE_00942	1.89e-275	-	-	-	-	-	-	-	-
AFAFIIAE_00943	6.91e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_00944	1.97e-125	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
AFAFIIAE_00945	5.49e-261	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
AFAFIIAE_00946	8.42e-135	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
AFAFIIAE_00947	3.42e-198	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
AFAFIIAE_00948	1.76e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AFAFIIAE_00949	1.12e-209	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AFAFIIAE_00950	9.79e-143	-	-	-	GM	-	-	-	NAD(P)H-binding
AFAFIIAE_00951	1.07e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
AFAFIIAE_00952	9.11e-101	yphH	-	-	S	-	-	-	Cupin domain
AFAFIIAE_00953	1.99e-205	-	-	-	K	-	-	-	Transcriptional regulator
AFAFIIAE_00954	5.16e-142	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
AFAFIIAE_00955	9.6e-217	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
AFAFIIAE_00956	1.74e-152	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
AFAFIIAE_00957	1.19e-200	-	-	-	T	-	-	-	GHKL domain
AFAFIIAE_00958	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
AFAFIIAE_00959	8.16e-203	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
AFAFIIAE_00960	2.05e-173	-	-	-	F	-	-	-	deoxynucleoside kinase
AFAFIIAE_00961	2.93e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
AFAFIIAE_00962	3.91e-217	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
AFAFIIAE_00963	1.15e-196	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AFAFIIAE_00964	1.89e-157	-	-	-	G	-	-	-	alpha-ribazole phosphatase activity
AFAFIIAE_00965	4.62e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
AFAFIIAE_00966	1.02e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
AFAFIIAE_00967	5.99e-141	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
AFAFIIAE_00968	2.76e-99	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
AFAFIIAE_00969	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
AFAFIIAE_00970	7.77e-74	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
AFAFIIAE_00972	1.94e-251	-	-	-	-	-	-	-	-
AFAFIIAE_00973	9.5e-199	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
AFAFIIAE_00974	1.92e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
AFAFIIAE_00975	2.6e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
AFAFIIAE_00977	1.5e-156	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
AFAFIIAE_00978	2.23e-191	-	-	-	I	-	-	-	alpha/beta hydrolase fold
AFAFIIAE_00979	1.26e-269	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
AFAFIIAE_00981	7.42e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
AFAFIIAE_00982	6.8e-21	-	-	-	-	-	-	-	-
AFAFIIAE_00983	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
AFAFIIAE_00984	3.77e-269	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AFAFIIAE_00985	3.73e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
AFAFIIAE_00986	4.13e-181	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
AFAFIIAE_00987	1.25e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
AFAFIIAE_00988	1.3e-121	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
AFAFIIAE_00989	1.03e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
AFAFIIAE_00990	7.11e-225	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
AFAFIIAE_00991	4.48e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
AFAFIIAE_00992	9.83e-37	-	-	-	-	-	-	-	-
AFAFIIAE_00993	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
AFAFIIAE_00994	2.68e-67	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
AFAFIIAE_00995	4.58e-109	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AFAFIIAE_00998	6.81e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
AFAFIIAE_00999	1.39e-217	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
AFAFIIAE_01000	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
AFAFIIAE_01001	4.24e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
AFAFIIAE_01002	1.1e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AFAFIIAE_01003	1.37e-64	-	-	-	M	-	-	-	Glycosyltransferase like family 2
AFAFIIAE_01004	4.62e-91	-	-	-	M	-	-	-	Glycosyltransferase like family 2
AFAFIIAE_01005	2.04e-63	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFAFIIAE_01006	3.51e-274	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFAFIIAE_01007	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
AFAFIIAE_01008	1.56e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
AFAFIIAE_01009	8.59e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
AFAFIIAE_01010	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
AFAFIIAE_01011	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
AFAFIIAE_01012	4.48e-21	-	-	-	-	-	-	-	-
AFAFIIAE_01014	9.85e-197	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
AFAFIIAE_01015	4.49e-180	-	-	-	L	-	-	-	Helix-turn-helix domain
AFAFIIAE_01021	1.66e-59	-	-	-	S	-	-	-	Domain of unknown function (DUF1883)
AFAFIIAE_01023	2.23e-179	-	-	-	S	-	-	-	ORF6N domain
AFAFIIAE_01024	4.03e-202	ps305	-	-	S	-	-	-	Protein of unknown function (Hypoth_ymh)
AFAFIIAE_01027	1.51e-80	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AFAFIIAE_01028	2.33e-25	-	-	-	E	-	-	-	Zn peptidase
AFAFIIAE_01029	1.4e-172	-	-	-	-	-	-	-	-
AFAFIIAE_01033	5.52e-286	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AFAFIIAE_01035	2.14e-24	-	-	-	-	-	-	-	-
AFAFIIAE_01036	2.2e-222	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
AFAFIIAE_01037	6.47e-205	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
AFAFIIAE_01038	2.98e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFAFIIAE_01039	1e-271	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
AFAFIIAE_01040	8.84e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFAFIIAE_01041	1.26e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
AFAFIIAE_01042	4.46e-204	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
AFAFIIAE_01043	3.89e-210	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
AFAFIIAE_01044	1.66e-117	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
AFAFIIAE_01045	0.0	ycaM	-	-	E	-	-	-	amino acid
AFAFIIAE_01046	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
AFAFIIAE_01047	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
AFAFIIAE_01048	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
AFAFIIAE_01049	4.64e-117	-	-	-	-	-	-	-	-
AFAFIIAE_01050	7.61e-269	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
AFAFIIAE_01051	9.28e-179	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
AFAFIIAE_01052	3.03e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
AFAFIIAE_01053	9.85e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
AFAFIIAE_01054	4.73e-31	-	-	-	-	-	-	-	-
AFAFIIAE_01055	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
AFAFIIAE_01056	4.94e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
AFAFIIAE_01057	1.34e-277	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AFAFIIAE_01058	4.72e-244	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
AFAFIIAE_01059	4.15e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
AFAFIIAE_01060	1.31e-149	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AFAFIIAE_01061	2.43e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFAFIIAE_01062	8.04e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
AFAFIIAE_01063	2.67e-186	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
AFAFIIAE_01064	3.19e-284	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
AFAFIIAE_01065	4.19e-65	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
AFAFIIAE_01066	1.41e-285	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
AFAFIIAE_01067	8.37e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
AFAFIIAE_01068	1.14e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
AFAFIIAE_01069	1.37e-26	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
AFAFIIAE_01070	4.12e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
AFAFIIAE_01071	8.38e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
AFAFIIAE_01072	1.88e-91	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
AFAFIIAE_01073	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AFAFIIAE_01074	1.92e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AFAFIIAE_01075	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AFAFIIAE_01076	3.93e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFAFIIAE_01077	3.59e-80	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AFAFIIAE_01078	2.57e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFAFIIAE_01079	1.23e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
AFAFIIAE_01080	3.05e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AFAFIIAE_01081	1.57e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AFAFIIAE_01082	5.71e-237	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AFAFIIAE_01083	6.65e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AFAFIIAE_01084	8.62e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AFAFIIAE_01085	7.61e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
AFAFIIAE_01086	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
AFAFIIAE_01087	1.07e-250	ampC	-	-	V	-	-	-	Beta-lactamase
AFAFIIAE_01088	9.19e-209	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
AFAFIIAE_01089	1.24e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
AFAFIIAE_01090	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
AFAFIIAE_01091	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_01092	6.41e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AFAFIIAE_01093	4.1e-163	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
AFAFIIAE_01095	3.91e-149	-	-	-	EP	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
AFAFIIAE_01097	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
AFAFIIAE_01098	2.3e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
AFAFIIAE_01100	1.38e-55	-	-	-	-	-	-	-	-
AFAFIIAE_01101	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
AFAFIIAE_01102	2.05e-109	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
AFAFIIAE_01103	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
AFAFIIAE_01104	2.14e-29	-	-	-	-	-	-	-	-
AFAFIIAE_01105	1.05e-298	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
AFAFIIAE_01106	3.43e-96	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
AFAFIIAE_01107	1.97e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
AFAFIIAE_01108	1.07e-104	yjhE	-	-	S	-	-	-	Phage tail protein
AFAFIIAE_01109	6.29e-307	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
AFAFIIAE_01110	8.14e-240	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
AFAFIIAE_01111	4.03e-164	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
AFAFIIAE_01112	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
AFAFIIAE_01113	2.68e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_01114	0.0	-	-	-	E	-	-	-	Amino Acid
AFAFIIAE_01115	2.01e-210	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
AFAFIIAE_01116	3.75e-303	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AFAFIIAE_01117	4.85e-201	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
AFAFIIAE_01118	0.0	-	-	-	M	-	-	-	Sulfatase
AFAFIIAE_01119	1.14e-219	-	-	-	S	-	-	-	EpsG family
AFAFIIAE_01120	1.81e-99	-	-	-	D	-	-	-	Capsular exopolysaccharide family
AFAFIIAE_01121	2.95e-119	ywqC	-	-	M	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	capsule polysaccharide biosynthetic process
AFAFIIAE_01122	3.04e-305	-	-	-	S	-	-	-	polysaccharide biosynthetic process
AFAFIIAE_01123	4.4e-244	-	-	-	M	-	-	-	Glycosyl transferases group 1
AFAFIIAE_01124	7.38e-127	tagF	2.7.8.12	-	M	ko:K09809,ko:K19046	-	ko00000,ko01000,ko02048	Glycosyl transferase, family 2
AFAFIIAE_01125	2.44e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
AFAFIIAE_01126	1.19e-294	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
AFAFIIAE_01127	1.04e-30	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
AFAFIIAE_01128	3.68e-170	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
AFAFIIAE_01129	1.2e-105	ccl	-	-	S	-	-	-	QueT transporter
AFAFIIAE_01130	7.35e-160	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
AFAFIIAE_01131	3.49e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
AFAFIIAE_01133	4.17e-149	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
AFAFIIAE_01134	2.59e-229	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
AFAFIIAE_01135	4.99e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
AFAFIIAE_01136	3.01e-227	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFAFIIAE_01137	1.4e-208	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFAFIIAE_01138	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
AFAFIIAE_01139	7.55e-243	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
AFAFIIAE_01140	2.31e-60	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
AFAFIIAE_01141	4.1e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFAFIIAE_01142	3.29e-171	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
AFAFIIAE_01143	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
AFAFIIAE_01144	1.7e-190	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
AFAFIIAE_01145	2.39e-109	-	-	-	-	-	-	-	-
AFAFIIAE_01146	1.27e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
AFAFIIAE_01147	1.79e-268	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
AFAFIIAE_01148	1.89e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
AFAFIIAE_01150	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFAFIIAE_01152	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
AFAFIIAE_01153	5.22e-174	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
AFAFIIAE_01154	2.49e-177	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
AFAFIIAE_01155	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
AFAFIIAE_01156	1.25e-102	-	-	-	-	-	-	-	-
AFAFIIAE_01157	1.32e-76	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
AFAFIIAE_01158	5.62e-185	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
AFAFIIAE_01159	1.88e-131	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
AFAFIIAE_01160	1.85e-173	-	-	-	-	-	-	-	-
AFAFIIAE_01161	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
AFAFIIAE_01162	0.0	-	-	-	S	-	-	-	PglZ domain
AFAFIIAE_01163	2.69e-130	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
AFAFIIAE_01164	5.39e-114	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
AFAFIIAE_01165	6.06e-147	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_01166	4.25e-150	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_01167	1.31e-303	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
AFAFIIAE_01169	1.33e-17	-	-	-	S	-	-	-	YvrJ protein family
AFAFIIAE_01170	2.15e-180	-	-	-	M	-	-	-	hydrolase, family 25
AFAFIIAE_01171	1.26e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AFAFIIAE_01172	9.42e-237	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
AFAFIIAE_01173	5.82e-153	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_01174	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
AFAFIIAE_01175	7.51e-194	-	-	-	S	-	-	-	hydrolase
AFAFIIAE_01176	1.49e-58	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
AFAFIIAE_01177	1.64e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
AFAFIIAE_01178	8.56e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
AFAFIIAE_01179	2.18e-177	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
AFAFIIAE_01180	7.9e-196	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
AFAFIIAE_01181	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
AFAFIIAE_01182	8.75e-90	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
AFAFIIAE_01183	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
AFAFIIAE_01184	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
AFAFIIAE_01185	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
AFAFIIAE_01187	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
AFAFIIAE_01188	6.39e-200	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
AFAFIIAE_01189	5.84e-253	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
AFAFIIAE_01190	1.75e-105	-	-	-	-	-	-	-	-
AFAFIIAE_01191	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
AFAFIIAE_01192	7.24e-23	-	-	-	-	-	-	-	-
AFAFIIAE_01193	2.03e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AFAFIIAE_01194	2.1e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
AFAFIIAE_01195	2.35e-132	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
AFAFIIAE_01196	1.03e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
AFAFIIAE_01197	1.38e-97	-	-	-	O	-	-	-	OsmC-like protein
AFAFIIAE_01199	6.83e-91	-	-	-	-	-	-	-	-
AFAFIIAE_01200	8.37e-116	-	-	-	S	-	-	-	Flavin reductase like domain
AFAFIIAE_01201	8.47e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
AFAFIIAE_01202	3.6e-59	-	-	-	-	-	-	-	-
AFAFIIAE_01203	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AFAFIIAE_01204	1.58e-33	-	-	-	-	-	-	-	-
AFAFIIAE_01205	5.77e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
AFAFIIAE_01206	1.03e-103	-	-	-	-	-	-	-	-
AFAFIIAE_01207	1.32e-71	-	-	-	-	-	-	-	-
AFAFIIAE_01209	2.02e-245	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
AFAFIIAE_01210	4.91e-55	-	-	-	-	-	-	-	-
AFAFIIAE_01211	2.7e-62	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
AFAFIIAE_01212	1.17e-77	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
AFAFIIAE_01213	6.22e-243	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
AFAFIIAE_01216	1.24e-260	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
AFAFIIAE_01217	2.41e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
AFAFIIAE_01218	1.41e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
AFAFIIAE_01219	1.12e-208	-	-	-	S	-	-	-	KR domain
AFAFIIAE_01220	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
AFAFIIAE_01221	2.42e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
AFAFIIAE_01222	4.26e-309	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
AFAFIIAE_01223	3.91e-159	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
AFAFIIAE_01224	3.08e-93	-	-	-	S	-	-	-	GtrA-like protein
AFAFIIAE_01225	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
AFAFIIAE_01226	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
AFAFIIAE_01227	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
AFAFIIAE_01228	1.43e-223	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
AFAFIIAE_01229	3.37e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_01230	2.78e-207	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
AFAFIIAE_01231	2.07e-213	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_01232	3.73e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
AFAFIIAE_01233	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
AFAFIIAE_01234	1.56e-64	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
AFAFIIAE_01238	1.98e-91	-	-	-	-	-	-	-	-
AFAFIIAE_01239	4.56e-267	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AFAFIIAE_01240	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_01241	3.99e-106	-	-	-	K	-	-	-	MerR HTH family regulatory protein
AFAFIIAE_01242	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
AFAFIIAE_01243	1.77e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
AFAFIIAE_01244	3.66e-155	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
AFAFIIAE_01245	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
AFAFIIAE_01246	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
AFAFIIAE_01247	4.65e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
AFAFIIAE_01248	9.15e-45	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AFAFIIAE_01249	3.37e-183	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AFAFIIAE_01250	2.55e-121	-	-	-	F	-	-	-	NUDIX domain
AFAFIIAE_01252	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
AFAFIIAE_01253	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
AFAFIIAE_01254	9.78e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
AFAFIIAE_01257	2.22e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
AFAFIIAE_01258	0.0	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
AFAFIIAE_01259	5.05e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
AFAFIIAE_01260	5.58e-312	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
AFAFIIAE_01261	3.47e-272	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
AFAFIIAE_01262	6.41e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
AFAFIIAE_01263	7.28e-138	-	-	-	S	-	-	-	CYTH
AFAFIIAE_01264	1.19e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
AFAFIIAE_01265	1.05e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFAFIIAE_01266	2.46e-219	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
AFAFIIAE_01267	9.8e-259	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AFAFIIAE_01268	1.51e-146	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
AFAFIIAE_01269	1.09e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AFAFIIAE_01270	9.35e-254	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
AFAFIIAE_01271	2e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
AFAFIIAE_01272	8.32e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFAFIIAE_01273	4.94e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AFAFIIAE_01274	2.27e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
AFAFIIAE_01275	3.44e-200	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
AFAFIIAE_01276	3.21e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AFAFIIAE_01277	4.04e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
AFAFIIAE_01278	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
AFAFIIAE_01279	2.7e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
AFAFIIAE_01280	1.61e-308	ymfH	-	-	S	-	-	-	Peptidase M16
AFAFIIAE_01281	3.01e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
AFAFIIAE_01282	1.15e-169	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
AFAFIIAE_01283	9.93e-136	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFAFIIAE_01285	1.18e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
AFAFIIAE_01286	9.19e-244	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AFAFIIAE_01287	7.95e-317	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
AFAFIIAE_01288	4.86e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
AFAFIIAE_01289	1.11e-299	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
AFAFIIAE_01290	4.32e-104	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
AFAFIIAE_01291	3.24e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AFAFIIAE_01292	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AFAFIIAE_01293	8.69e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AFAFIIAE_01294	1.28e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
AFAFIIAE_01296	3.16e-258	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
AFAFIIAE_01297	1.83e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
AFAFIIAE_01298	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
AFAFIIAE_01299	1.76e-196	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
AFAFIIAE_01300	4.48e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
AFAFIIAE_01301	1.06e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
AFAFIIAE_01302	9.06e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFAFIIAE_01303	2.05e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFAFIIAE_01304	3.82e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
AFAFIIAE_01305	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
AFAFIIAE_01306	5.23e-50	-	-	-	-	-	-	-	-
AFAFIIAE_01307	3.07e-50	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
AFAFIIAE_01308	8.27e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AFAFIIAE_01309	9.99e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AFAFIIAE_01310	6.29e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
AFAFIIAE_01311	4.11e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AFAFIIAE_01312	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
AFAFIIAE_01313	3.04e-148	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
AFAFIIAE_01314	4.62e-222	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
AFAFIIAE_01315	1.47e-118	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_01316	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
AFAFIIAE_01317	1.99e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
AFAFIIAE_01318	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AFAFIIAE_01319	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AFAFIIAE_01320	2.56e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
AFAFIIAE_01321	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
AFAFIIAE_01322	2.99e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
AFAFIIAE_01323	9.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
AFAFIIAE_01324	2e-65	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
AFAFIIAE_01325	5.97e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AFAFIIAE_01329	6.02e-78	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
AFAFIIAE_01330	5.52e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
AFAFIIAE_01331	2.1e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFAFIIAE_01332	2.16e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
AFAFIIAE_01333	2.81e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AFAFIIAE_01334	2.05e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AFAFIIAE_01335	1.49e-292	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
AFAFIIAE_01336	4.46e-62	-	-	-	-	-	-	-	-
AFAFIIAE_01337	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
AFAFIIAE_01338	5.04e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
AFAFIIAE_01339	4.01e-181	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
AFAFIIAE_01340	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AFAFIIAE_01341	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AFAFIIAE_01342	1.81e-225	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
AFAFIIAE_01343	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
AFAFIIAE_01344	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
AFAFIIAE_01345	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
AFAFIIAE_01346	3.49e-155	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
AFAFIIAE_01347	7.87e-269	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
AFAFIIAE_01348	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
AFAFIIAE_01349	5.61e-292	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
AFAFIIAE_01350	5.9e-313	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_01351	5.43e-195	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AFAFIIAE_01353	1.13e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
AFAFIIAE_01354	4.2e-305	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
AFAFIIAE_01355	4.64e-205	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AFAFIIAE_01356	9.86e-282	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
AFAFIIAE_01357	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
AFAFIIAE_01358	9.12e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
AFAFIIAE_01359	0.0	strH	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Gram-positive signal peptide protein, YSIRK family
AFAFIIAE_01360	3.14e-109	-	-	-	-	-	-	-	-
AFAFIIAE_01361	2.46e-307	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
AFAFIIAE_01362	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
AFAFIIAE_01363	1.09e-151	-	-	-	-	-	-	-	-
AFAFIIAE_01364	3.19e-181	-	-	-	-	-	-	-	-
AFAFIIAE_01365	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
AFAFIIAE_01368	5.95e-199	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
AFAFIIAE_01369	3.82e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
AFAFIIAE_01370	4.6e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AFAFIIAE_01371	1.01e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AFAFIIAE_01372	1.18e-151	-	-	-	G	-	-	-	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AFAFIIAE_01373	2.26e-303	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFAFIIAE_01374	7.59e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
AFAFIIAE_01375	1.16e-159	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_01376	3.01e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
AFAFIIAE_01377	1.1e-182	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
AFAFIIAE_01378	1.04e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
AFAFIIAE_01379	2.67e-272	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
AFAFIIAE_01381	2.51e-98	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
AFAFIIAE_01382	8.95e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
AFAFIIAE_01383	3.02e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
AFAFIIAE_01384	3.98e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AFAFIIAE_01385	7.78e-260	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AFAFIIAE_01386	6.23e-303	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
AFAFIIAE_01387	2.27e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AFAFIIAE_01388	1.45e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
AFAFIIAE_01389	5.61e-108	yvbK	-	-	K	-	-	-	GNAT family
AFAFIIAE_01390	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
AFAFIIAE_01391	1.71e-216	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
AFAFIIAE_01392	5.17e-134	-	-	-	-	-	-	-	-
AFAFIIAE_01393	3.35e-217	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
AFAFIIAE_01394	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
AFAFIIAE_01395	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
AFAFIIAE_01396	2.49e-191	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
AFAFIIAE_01397	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
AFAFIIAE_01398	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
AFAFIIAE_01399	3.11e-164	-	-	-	N	-	-	-	domain, Protein
AFAFIIAE_01400	1.04e-72	-	-	-	N	-	-	-	domain, Protein
AFAFIIAE_01401	2.25e-110	-	-	-	M	-	-	-	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AFAFIIAE_01402	1.02e-201	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
AFAFIIAE_01403	3.22e-11	-	-	-	-	-	-	-	-
AFAFIIAE_01404	4.77e-62	-	-	-	-	-	-	-	-
AFAFIIAE_01405	2.83e-92	-	-	-	M	-	-	-	Glycosyl transferases group 1
AFAFIIAE_01407	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFAFIIAE_01408	2.36e-167	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
AFAFIIAE_01409	1.88e-223	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
AFAFIIAE_01410	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AFAFIIAE_01411	5.24e-116	-	-	-	-	-	-	-	-
AFAFIIAE_01412	4.42e-154	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
AFAFIIAE_01413	2.66e-233	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AFAFIIAE_01414	2.87e-289	-	-	-	EK	-	-	-	Aminotransferase, class I
AFAFIIAE_01415	8.49e-211	-	-	-	K	-	-	-	LysR substrate binding domain
AFAFIIAE_01416	3.81e-115	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFAFIIAE_01417	7.22e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
AFAFIIAE_01418	4.48e-161	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
AFAFIIAE_01419	3.43e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
AFAFIIAE_01420	1.99e-16	-	-	-	-	-	-	-	-
AFAFIIAE_01421	4.04e-79	-	-	-	-	-	-	-	-
AFAFIIAE_01422	6.84e-186	-	-	-	S	-	-	-	hydrolase
AFAFIIAE_01423	6.25e-246	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
AFAFIIAE_01424	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
AFAFIIAE_01425	6.41e-92	-	-	-	K	-	-	-	MarR family
AFAFIIAE_01426	8.07e-148	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
AFAFIIAE_01428	1.15e-147	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
AFAFIIAE_01429	6.52e-222	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
AFAFIIAE_01430	1.62e-192	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
AFAFIIAE_01431	0.0	-	-	-	L	-	-	-	DNA helicase
AFAFIIAE_01433	5.92e-09	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
AFAFIIAE_01434	4.89e-90	-	-	-	-	-	-	-	-
AFAFIIAE_01435	6.61e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
AFAFIIAE_01436	1.91e-31	-	-	-	-	-	-	-	-
AFAFIIAE_01437	0.000802	-	-	-	-	-	-	-	-
AFAFIIAE_01439	5.09e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
AFAFIIAE_01442	1.05e-23	-	-	-	-	-	-	-	-
AFAFIIAE_01444	3.29e-47	-	-	-	S	-	-	-	YopX protein
AFAFIIAE_01447	1.28e-93	-	-	-	-	-	-	-	-
AFAFIIAE_01449	4e-280	-	-	-	S	-	-	-	GcrA cell cycle regulator
AFAFIIAE_01451	5.96e-17	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
AFAFIIAE_01452	6.23e-261	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
AFAFIIAE_01453	8.92e-151	-	-	-	S	-	-	-	portal protein
AFAFIIAE_01454	1.59e-94	-	-	-	M	-	-	-	Phage minor capsid protein 2
AFAFIIAE_01455	4.32e-35	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
AFAFIIAE_01456	7.98e-36	-	-	-	-	-	-	-	-
AFAFIIAE_01457	3.51e-25	-	-	-	S	-	-	-	Phage minor structural protein GP20
AFAFIIAE_01458	3.24e-95	-	-	-	-	-	-	-	-
AFAFIIAE_01460	5.87e-11	-	-	-	S	-	-	-	Minor capsid protein
AFAFIIAE_01463	6.16e-57	-	-	-	-	-	-	-	-
AFAFIIAE_01464	4.18e-29	-	-	-	N	-	-	-	domain, Protein
AFAFIIAE_01466	2.81e-37	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
AFAFIIAE_01467	6.16e-81	-	-	-	S	-	-	-	phage tail tape measure protein
AFAFIIAE_01468	9.42e-270	-	-	-	S	-	-	-	Phage tail protein
AFAFIIAE_01469	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
AFAFIIAE_01470	8.12e-69	-	-	-	-	-	-	-	-
AFAFIIAE_01472	2.74e-59	-	-	-	-	-	-	-	-
AFAFIIAE_01473	5.61e-84	hol	-	-	S	-	-	-	Bacteriophage holin
AFAFIIAE_01474	6.05e-196	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
AFAFIIAE_01475	2.32e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
AFAFIIAE_01476	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
AFAFIIAE_01477	1.94e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
AFAFIIAE_01478	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
AFAFIIAE_01479	1.29e-186	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFAFIIAE_01480	1.92e-42	-	-	-	M	-	-	-	Sortase family
AFAFIIAE_01481	5.79e-83	-	-	-	M	-	-	-	Sortase family
AFAFIIAE_01482	8.73e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
AFAFIIAE_01483	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AFAFIIAE_01484	6.83e-255	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AFAFIIAE_01485	1.13e-253	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
AFAFIIAE_01486	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
AFAFIIAE_01487	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AFAFIIAE_01488	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
AFAFIIAE_01489	3.12e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AFAFIIAE_01490	5.83e-73	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
AFAFIIAE_01491	1.32e-221	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFAFIIAE_01492	1.27e-311	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFAFIIAE_01493	4.22e-41	-	-	-	-	-	-	-	-
AFAFIIAE_01494	1.89e-133	-	-	-	-	-	-	-	-
AFAFIIAE_01495	3.79e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
AFAFIIAE_01496	4.58e-305	-	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_01497	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
AFAFIIAE_01498	3.61e-55	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
AFAFIIAE_01499	1.34e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AFAFIIAE_01500	1.41e-214	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
AFAFIIAE_01501	4.84e-198	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
AFAFIIAE_01502	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
AFAFIIAE_01503	3.66e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
AFAFIIAE_01504	2.08e-240	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
AFAFIIAE_01505	1.16e-45	-	-	-	-	-	-	-	-
AFAFIIAE_01506	0.0	-	-	-	E	-	-	-	Amino acid permease
AFAFIIAE_01507	1.82e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
AFAFIIAE_01508	3.36e-135	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
AFAFIIAE_01509	7.14e-193	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AFAFIIAE_01510	5.11e-107	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
AFAFIIAE_01511	1.98e-165	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AFAFIIAE_01512	4.45e-133	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
AFAFIIAE_01513	4.66e-312	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
AFAFIIAE_01514	4.57e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
AFAFIIAE_01516	3.82e-141	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
AFAFIIAE_01517	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
AFAFIIAE_01518	2.45e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
AFAFIIAE_01519	7.09e-113	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
AFAFIIAE_01520	5.77e-93	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
AFAFIIAE_01521	1.01e-104	-	-	-	C	-	-	-	Flavodoxin
AFAFIIAE_01522	9.69e-234	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
AFAFIIAE_01523	6.48e-147	-	-	-	GM	-	-	-	NmrA-like family
AFAFIIAE_01525	2.29e-131	-	-	-	Q	-	-	-	methyltransferase
AFAFIIAE_01526	3.14e-142	-	-	-	T	-	-	-	Sh3 type 3 domain protein
AFAFIIAE_01527	6.72e-152	-	-	-	F	-	-	-	glutamine amidotransferase
AFAFIIAE_01528	5.22e-174	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
AFAFIIAE_01529	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
AFAFIIAE_01530	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
AFAFIIAE_01531	8.38e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
AFAFIIAE_01532	4.8e-128	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
AFAFIIAE_01533	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AFAFIIAE_01534	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AFAFIIAE_01535	0.0	ydaO	-	-	E	-	-	-	amino acid
AFAFIIAE_01536	5.32e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
AFAFIIAE_01537	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AFAFIIAE_01538	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AFAFIIAE_01539	6.1e-143	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
AFAFIIAE_01540	1.01e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
AFAFIIAE_01541	5.46e-45	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
AFAFIIAE_01542	1.15e-06	-	-	-	-	-	-	-	-
AFAFIIAE_01543	1.25e-174	-	-	-	-	-	-	-	-
AFAFIIAE_01544	1.5e-112	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
AFAFIIAE_01545	1.01e-122	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
AFAFIIAE_01546	1.64e-204	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
AFAFIIAE_01547	2.14e-234	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
AFAFIIAE_01549	2.38e-226	-	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFAFIIAE_01550	1.2e-214	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_01551	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
AFAFIIAE_01552	1.22e-125	-	-	-	S	-	-	-	DJ-1/PfpI family
AFAFIIAE_01553	2.48e-69	-	-	-	K	-	-	-	Transcriptional
AFAFIIAE_01554	7.53e-49	-	-	-	-	-	-	-	-
AFAFIIAE_01555	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
AFAFIIAE_01556	2.8e-261	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
AFAFIIAE_01557	1.2e-79	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
AFAFIIAE_01559	3.24e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
AFAFIIAE_01560	3.05e-19	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
AFAFIIAE_01561	2.58e-152	-	-	-	M	-	-	-	LysM domain
AFAFIIAE_01562	1.85e-196	-	-	-	M	-	-	-	LysM domain
AFAFIIAE_01563	9.68e-173	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
AFAFIIAE_01564	7.3e-169	-	-	-	K	-	-	-	DeoR C terminal sensor domain
AFAFIIAE_01566	3.93e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_01567	1.02e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AFAFIIAE_01568	2.28e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AFAFIIAE_01569	7.8e-282	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_01570	0.000666	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
AFAFIIAE_01572	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
AFAFIIAE_01573	2.09e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
AFAFIIAE_01574	4.72e-128	dpsB	-	-	P	-	-	-	Belongs to the Dps family
AFAFIIAE_01575	1.23e-149	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
AFAFIIAE_01576	6.56e-181	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AFAFIIAE_01577	1.18e-291	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AFAFIIAE_01578	3.12e-52	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
AFAFIIAE_01579	6.65e-66	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
AFAFIIAE_01580	4.43e-177	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
AFAFIIAE_01581	1.19e-233	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AFAFIIAE_01582	2.07e-262	-	-	-	-	-	-	-	-
AFAFIIAE_01583	0.0	-	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_01584	1.04e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AFAFIIAE_01586	6.98e-155	-	-	-	-	-	-	-	-
AFAFIIAE_01588	1.15e-86	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
AFAFIIAE_01590	1.96e-206	-	-	-	L	-	-	-	Replication initiation and membrane attachment
AFAFIIAE_01591	6.74e-193	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
AFAFIIAE_01592	3.06e-202	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
AFAFIIAE_01594	4.2e-22	-	-	-	-	-	-	-	-
AFAFIIAE_01596	2.21e-127	-	-	-	-	-	-	-	-
AFAFIIAE_01600	9.99e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AFAFIIAE_01601	1.1e-28	-	-	-	K	-	-	-	transcriptional
AFAFIIAE_01602	6.35e-10	-	-	-	E	-	-	-	Zn peptidase
AFAFIIAE_01603	2.78e-135	-	-	-	S	ko:K07504	-	ko00000	Type I restriction enzyme R protein N terminus (HSDR_N)
AFAFIIAE_01605	3.98e-92	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
AFAFIIAE_01606	1.47e-37	-	-	-	-	-	-	-	-
AFAFIIAE_01607	5.41e-39	-	-	-	-	-	-	-	-
AFAFIIAE_01608	8.21e-53	-	-	-	S	-	-	-	Domain of unknown function DUF1828
AFAFIIAE_01609	2.09e-288	-	-	-	L	-	-	-	Pfam:Integrase_AP2
AFAFIIAE_01610	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
AFAFIIAE_01611	4.66e-196	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
AFAFIIAE_01612	2.63e-142	vanZ	-	-	V	-	-	-	VanZ like family
AFAFIIAE_01613	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AFAFIIAE_01614	2.11e-137	-	-	-	-	-	-	-	-
AFAFIIAE_01615	7.65e-136	-	-	-	-	-	-	-	-
AFAFIIAE_01616	8.67e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
AFAFIIAE_01617	4.46e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
AFAFIIAE_01618	7.01e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
AFAFIIAE_01619	3.08e-248	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
AFAFIIAE_01620	3.63e-136	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
AFAFIIAE_01621	7.57e-119	-	-	-	-	-	-	-	-
AFAFIIAE_01622	4e-203	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
AFAFIIAE_01623	1.45e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AFAFIIAE_01624	1.75e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
AFAFIIAE_01625	3.18e-106	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
AFAFIIAE_01626	4.05e-18	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AFAFIIAE_01627	1.71e-209	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_01628	1.8e-275	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
AFAFIIAE_01629	8.04e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
AFAFIIAE_01630	8.14e-194	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
AFAFIIAE_01631	4.74e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
AFAFIIAE_01632	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
AFAFIIAE_01633	1.97e-124	-	-	-	K	-	-	-	Cupin domain
AFAFIIAE_01634	9.1e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AFAFIIAE_01635	1.44e-189	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AFAFIIAE_01636	2.88e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AFAFIIAE_01637	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_01639	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
AFAFIIAE_01640	5.23e-144	-	-	-	K	-	-	-	Transcriptional regulator
AFAFIIAE_01641	1.33e-240	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_01642	2.21e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
AFAFIIAE_01643	3.82e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFAFIIAE_01644	1.36e-217	ybbR	-	-	S	-	-	-	YbbR-like protein
AFAFIIAE_01645	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFAFIIAE_01646	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AFAFIIAE_01648	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
AFAFIIAE_01649	3.35e-106	-	-	-	S	-	-	-	VanZ like family
AFAFIIAE_01650	5.85e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
AFAFIIAE_01651	2.91e-196	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
AFAFIIAE_01652	3.08e-216	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
AFAFIIAE_01653	1e-35	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
AFAFIIAE_01655	5.46e-31	-	-	-	-	-	-	-	-
AFAFIIAE_01656	2.01e-24	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
AFAFIIAE_01658	3.06e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
AFAFIIAE_01659	8.54e-81	-	-	-	-	-	-	-	-
AFAFIIAE_01660	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
AFAFIIAE_01661	7.51e-191	arbV	-	-	I	-	-	-	Phosphate acyltransferases
AFAFIIAE_01662	8.22e-212	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
AFAFIIAE_01663	1.9e-232	arbY	-	-	M	-	-	-	family 8
AFAFIIAE_01664	1.79e-211	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
AFAFIIAE_01665	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
AFAFIIAE_01668	9.31e-93	-	-	-	S	-	-	-	SdpI/YhfL protein family
AFAFIIAE_01669	1.02e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
AFAFIIAE_01670	0.0	yclK	-	-	T	-	-	-	Histidine kinase
AFAFIIAE_01671	4.67e-97	-	-	-	S	-	-	-	acetyltransferase
AFAFIIAE_01672	7.39e-20	-	-	-	-	-	-	-	-
AFAFIIAE_01673	7.36e-94	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
AFAFIIAE_01674	1.53e-88	-	-	-	-	-	-	-	-
AFAFIIAE_01675	4.96e-73	-	-	-	-	-	-	-	-
AFAFIIAE_01676	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
AFAFIIAE_01678	3.59e-266	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
AFAFIIAE_01679	3.51e-180	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
AFAFIIAE_01680	5.65e-46	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
AFAFIIAE_01682	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
AFAFIIAE_01683	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AFAFIIAE_01684	4.26e-271	camS	-	-	S	-	-	-	sex pheromone
AFAFIIAE_01685	3.61e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFAFIIAE_01686	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AFAFIIAE_01687	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFAFIIAE_01688	4.97e-248	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
AFAFIIAE_01689	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFAFIIAE_01690	1.86e-280	yttB	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_01691	8.81e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
AFAFIIAE_01692	9.94e-210	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
AFAFIIAE_01693	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
AFAFIIAE_01694	0.0	-	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_01695	3.04e-84	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
AFAFIIAE_01696	2.87e-213	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
AFAFIIAE_01697	1.37e-165	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
AFAFIIAE_01698	1.24e-39	-	-	-	-	-	-	-	-
AFAFIIAE_01699	1.98e-177	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
AFAFIIAE_01700	9.39e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
AFAFIIAE_01701	1.9e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
AFAFIIAE_01702	2.21e-226	mocA	-	-	S	-	-	-	Oxidoreductase
AFAFIIAE_01703	5.15e-288	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
AFAFIIAE_01704	7.9e-74	chbA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
AFAFIIAE_01705	4.49e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
AFAFIIAE_01707	1.6e-05	-	-	-	-	-	-	-	-
AFAFIIAE_01708	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
AFAFIIAE_01709	6.16e-301	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
AFAFIIAE_01710	2.96e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AFAFIIAE_01712	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
AFAFIIAE_01713	9.73e-230	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
AFAFIIAE_01714	1.24e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
AFAFIIAE_01715	1.16e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
AFAFIIAE_01716	7.16e-257	-	-	-	M	-	-	-	Glycosyltransferase like family 2
AFAFIIAE_01718	1.02e-20	-	-	-	-	-	-	-	-
AFAFIIAE_01719	1.09e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
AFAFIIAE_01720	1.31e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
AFAFIIAE_01722	2.93e-209	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
AFAFIIAE_01723	4.63e-127	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
AFAFIIAE_01725	1.88e-63	-	-	-	-	-	-	-	-
AFAFIIAE_01726	0.0	-	-	-	K	-	-	-	Sigma-54 interaction domain
AFAFIIAE_01727	4.78e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
AFAFIIAE_01728	2.66e-117	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
AFAFIIAE_01729	5.43e-196	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
AFAFIIAE_01730	2.15e-199	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
AFAFIIAE_01731	9.35e-74	-	-	-	-	-	-	-	-
AFAFIIAE_01732	0.0	-	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
AFAFIIAE_01734	1.83e-156	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
AFAFIIAE_01735	2.38e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
AFAFIIAE_01736	1.14e-143	-	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
AFAFIIAE_01737	7.85e-124	-	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
AFAFIIAE_01738	0.0	-	2.7.1.197	-	G	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AFAFIIAE_01739	4.34e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
AFAFIIAE_01740	9.57e-244	-	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
AFAFIIAE_01741	1.8e-166	yxeO	-	-	E	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
AFAFIIAE_01742	1.54e-84	-	-	-	-	-	-	-	-
AFAFIIAE_01743	3.18e-285	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
AFAFIIAE_01744	3.69e-186	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
AFAFIIAE_01745	7.98e-75	-	-	-	K	-	-	-	Helix-turn-helix domain
AFAFIIAE_01746	9.59e-101	usp5	-	-	T	-	-	-	universal stress protein
AFAFIIAE_01747	3.45e-144	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
AFAFIIAE_01748	1.72e-213	-	-	-	EG	-	-	-	EamA-like transporter family
AFAFIIAE_01749	6.71e-34	-	-	-	-	-	-	-	-
AFAFIIAE_01750	4.98e-112	-	-	-	-	-	-	-	-
AFAFIIAE_01751	5.75e-52	-	-	-	-	-	-	-	-
AFAFIIAE_01752	1.03e-242	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AFAFIIAE_01753	2.74e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
AFAFIIAE_01755	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
AFAFIIAE_01756	2.5e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
AFAFIIAE_01757	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
AFAFIIAE_01758	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AFAFIIAE_01759	4.58e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
AFAFIIAE_01760	3.9e-83	-	-	-	-	-	-	-	-
AFAFIIAE_01761	1.87e-80	-	-	-	-	-	-	-	-
AFAFIIAE_01762	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
AFAFIIAE_01763	1.9e-249	-	-	-	GKT	-	-	-	transcriptional antiterminator
AFAFIIAE_01764	3.38e-66	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
AFAFIIAE_01765	5.62e-292	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
AFAFIIAE_01766	1.19e-88	-	-	-	-	-	-	-	-
AFAFIIAE_01767	6.47e-208	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
AFAFIIAE_01768	7.78e-150	-	-	-	S	-	-	-	Zeta toxin
AFAFIIAE_01769	3.2e-203	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
AFAFIIAE_01770	1.12e-189	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
AFAFIIAE_01771	2.9e-229	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
AFAFIIAE_01772	1.11e-190	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
AFAFIIAE_01777	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AFAFIIAE_01778	3.8e-308	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
AFAFIIAE_01779	9.15e-34	-	-	-	-	-	-	-	-
AFAFIIAE_01781	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
AFAFIIAE_01782	7.28e-41	spiA	-	-	K	-	-	-	TRANSCRIPTIONal
AFAFIIAE_01783	7.46e-59	-	-	-	S	-	-	-	Enterocin A Immunity
AFAFIIAE_01784	6.69e-61	-	-	-	S	-	-	-	Enterocin A Immunity
AFAFIIAE_01785	3.3e-151	-	-	-	-	-	-	-	-
AFAFIIAE_01786	0.0	-	-	-	L	-	-	-	Transposase DDE domain
AFAFIIAE_01787	1.36e-80	-	-	-	-	-	-	-	-
AFAFIIAE_01788	2.05e-72	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
AFAFIIAE_01789	2.06e-143	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AFAFIIAE_01790	2.83e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
AFAFIIAE_01791	2.34e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
AFAFIIAE_01792	1.48e-290	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
AFAFIIAE_01793	1.17e-82	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
AFAFIIAE_01794	2.99e-140	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AFAFIIAE_01795	1.35e-237	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
AFAFIIAE_01796	2.26e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
AFAFIIAE_01797	8.69e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
AFAFIIAE_01798	2.62e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
AFAFIIAE_01799	1.34e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AFAFIIAE_01800	1.02e-150	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
AFAFIIAE_01801	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
AFAFIIAE_01802	7.41e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
AFAFIIAE_01803	3.27e-151	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
AFAFIIAE_01804	1.7e-240	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
AFAFIIAE_01805	9.98e-73	-	-	-	-	-	-	-	-
AFAFIIAE_01806	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
AFAFIIAE_01807	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
AFAFIIAE_01808	5.87e-177	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AFAFIIAE_01809	1.21e-144	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
AFAFIIAE_01810	1.54e-57	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
AFAFIIAE_01811	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
AFAFIIAE_01812	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
AFAFIIAE_01813	8.23e-126	-	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Bacterial regulatory proteins, tetR family
AFAFIIAE_01814	4.4e-316	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
AFAFIIAE_01815	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
AFAFIIAE_01816	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
AFAFIIAE_01817	3.4e-82	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
AFAFIIAE_01818	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
AFAFIIAE_01819	1.51e-238	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AFAFIIAE_01820	1.69e-256	ald1	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
AFAFIIAE_01821	8.92e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
AFAFIIAE_01822	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AFAFIIAE_01823	1.52e-57	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
AFAFIIAE_01824	3.15e-277	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
AFAFIIAE_01826	1.58e-220	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AFAFIIAE_01827	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
AFAFIIAE_01828	1.09e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
AFAFIIAE_01829	0.0	ybeC	-	-	E	-	-	-	amino acid
AFAFIIAE_01830	2.38e-122	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
AFAFIIAE_01856	6.76e-116	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
AFAFIIAE_01857	4.95e-269	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
AFAFIIAE_01858	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AFAFIIAE_01859	1.09e-138	pncA	-	-	Q	-	-	-	Isochorismatase family
AFAFIIAE_01860	5.44e-174	-	-	-	F	-	-	-	NUDIX domain
AFAFIIAE_01861	2.8e-185	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
AFAFIIAE_01862	3.08e-243	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
AFAFIIAE_01863	6.03e-247	-	-	-	V	-	-	-	Beta-lactamase
AFAFIIAE_01864	1.43e-197	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AFAFIIAE_01865	3.72e-210	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
AFAFIIAE_01866	1.37e-104	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
AFAFIIAE_01867	1.56e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
AFAFIIAE_01868	8.76e-177	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
AFAFIIAE_01869	7.18e-227	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
AFAFIIAE_01870	8.37e-108	-	-	-	L	-	-	-	Transposase DDE domain
AFAFIIAE_01871	6.56e-87	glcU	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
AFAFIIAE_01872	6.72e-246	-	-	-	G	-	-	-	Glycosyl hydrolase
AFAFIIAE_01873	7.18e-174	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS mannose transporter subunit IIAB
AFAFIIAE_01874	4.44e-43	-	2.7.1.202	-	G	ko:K02769,ko:K11202	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
AFAFIIAE_01875	1.08e-37	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AFAFIIAE_01876	1.28e-124	manR	-	-	G	ko:K02538,ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
AFAFIIAE_01878	2.1e-143	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
AFAFIIAE_01880	1.9e-183	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
AFAFIIAE_01881	9.75e-85	-	-	-	-	-	-	-	-
AFAFIIAE_01882	5.44e-215	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
AFAFIIAE_01883	3.29e-183	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
AFAFIIAE_01884	1.29e-184	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
AFAFIIAE_01885	5.41e-191	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
AFAFIIAE_01886	1.66e-247	pbpE	-	-	V	-	-	-	Beta-lactamase
AFAFIIAE_01888	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
AFAFIIAE_01889	5.36e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
AFAFIIAE_01890	1.32e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
AFAFIIAE_01891	4.89e-139	ydfF	-	-	K	-	-	-	Transcriptional
AFAFIIAE_01892	1.82e-258	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
AFAFIIAE_01893	2.98e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
AFAFIIAE_01894	0.0	-	-	-	L	-	-	-	Exonuclease
AFAFIIAE_01896	6.01e-269	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
AFAFIIAE_01897	7.18e-79	-	-	-	-	-	-	-	-
AFAFIIAE_01898	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
AFAFIIAE_01899	2.68e-176	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_01900	3.48e-219	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
AFAFIIAE_01901	2.9e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
AFAFIIAE_01902	6.44e-242	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
AFAFIIAE_01903	5.88e-62	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AFAFIIAE_01904	6.86e-83	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AFAFIIAE_01905	2.92e-144	-	-	-	C	-	-	-	Nitroreductase family
AFAFIIAE_01906	2.22e-256	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AFAFIIAE_01907	6.09e-70	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
AFAFIIAE_01908	5.84e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AFAFIIAE_01909	1.42e-169	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AFAFIIAE_01910	1.08e-157	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AFAFIIAE_01911	4.89e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AFAFIIAE_01912	3.22e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
AFAFIIAE_01913	1.97e-293	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AFAFIIAE_01914	2.81e-142	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AFAFIIAE_01915	3.15e-277	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AFAFIIAE_01916	1.99e-260	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AFAFIIAE_01917	3.35e-129	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
AFAFIIAE_01918	2.95e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
AFAFIIAE_01919	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
AFAFIIAE_01920	1.73e-66	-	-	-	S	-	-	-	MazG-like family
AFAFIIAE_01921	8.21e-250	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
AFAFIIAE_01922	2.13e-227	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFAFIIAE_01923	7.77e-282	bfmBB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
AFAFIIAE_01924	1.24e-233	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
AFAFIIAE_01925	5.29e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
AFAFIIAE_01926	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
AFAFIIAE_01927	6.41e-261	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Acetokinase family
AFAFIIAE_01928	2.03e-189	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Phosphate acetyl/butaryl transferase
AFAFIIAE_01929	1.02e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFAFIIAE_01930	3.12e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AFAFIIAE_01931	1.63e-199	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AFAFIIAE_01932	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
AFAFIIAE_01933	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
AFAFIIAE_01934	5.73e-302	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AFAFIIAE_01935	7.64e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
AFAFIIAE_01936	1.64e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
AFAFIIAE_01937	1.05e-125	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AFAFIIAE_01938	5.18e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
AFAFIIAE_01939	2.41e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AFAFIIAE_01940	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
AFAFIIAE_01941	8.5e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
AFAFIIAE_01942	2.28e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
AFAFIIAE_01943	1.21e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
AFAFIIAE_01944	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFAFIIAE_01945	1.91e-63	-	-	-	-	-	-	-	-
AFAFIIAE_01946	1.52e-293	-	-	-	S	-	-	-	Mga helix-turn-helix domain
AFAFIIAE_01947	8.92e-26	-	-	-	S	-	-	-	Mga helix-turn-helix domain
AFAFIIAE_01948	8.72e-52	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
AFAFIIAE_01949	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFAFIIAE_01950	8.83e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFAFIIAE_01951	7.8e-206	lysR	-	-	K	-	-	-	Transcriptional regulator
AFAFIIAE_01952	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
AFAFIIAE_01953	2.02e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
AFAFIIAE_01954	7.29e-46	-	-	-	-	-	-	-	-
AFAFIIAE_01955	1.22e-220	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
AFAFIIAE_01956	9.39e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
AFAFIIAE_01957	7.09e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AFAFIIAE_01958	6.54e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
AFAFIIAE_01959	5.12e-157	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AFAFIIAE_01960	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
AFAFIIAE_01961	5.94e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
AFAFIIAE_01962	1.08e-147	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AFAFIIAE_01963	3.19e-146	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
AFAFIIAE_01964	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
AFAFIIAE_01965	3.29e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
AFAFIIAE_01966	1.01e-111	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
AFAFIIAE_01968	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
AFAFIIAE_01969	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
AFAFIIAE_01970	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
AFAFIIAE_01971	1.31e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
AFAFIIAE_01972	3.82e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
AFAFIIAE_01973	4.56e-244	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AFAFIIAE_01974	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
AFAFIIAE_01975	4.61e-224	-	-	-	-	-	-	-	-
AFAFIIAE_01976	1.06e-182	-	-	-	-	-	-	-	-
AFAFIIAE_01977	2.32e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
AFAFIIAE_01978	2.03e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
AFAFIIAE_01979	4.01e-191	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AFAFIIAE_01980	2.29e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
AFAFIIAE_01981	3.12e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AFAFIIAE_01982	1.7e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
AFAFIIAE_01983	2.2e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
AFAFIIAE_01984	4.86e-201	mleR	-	-	K	-	-	-	LysR family
AFAFIIAE_01985	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
AFAFIIAE_01986	3.58e-217	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
AFAFIIAE_01987	8.23e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AFAFIIAE_01988	3.78e-112	-	-	-	C	-	-	-	FMN binding
AFAFIIAE_01989	7.65e-223	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
AFAFIIAE_01990	2.95e-10	-	-	-	V	-	-	-	ABC transporter transmembrane region
AFAFIIAE_01991	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
AFAFIIAE_01992	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
AFAFIIAE_01993	3.86e-78	-	-	-	-	-	-	-	-
AFAFIIAE_01994	1.39e-185	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
AFAFIIAE_01995	2.34e-88	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AFAFIIAE_01996	7.28e-144	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
AFAFIIAE_01997	9.35e-15	-	-	-	-	-	-	-	-
AFAFIIAE_01998	1.12e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
AFAFIIAE_02000	3.13e-227	-	-	-	-	-	-	-	-
AFAFIIAE_02001	6.35e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_02002	2.05e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
AFAFIIAE_02003	1.44e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AFAFIIAE_02004	6.51e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AFAFIIAE_02005	6.58e-225	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
AFAFIIAE_02006	5.55e-139	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
AFAFIIAE_02007	2.17e-161	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
AFAFIIAE_02008	3.55e-312	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
AFAFIIAE_02009	1.68e-67	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
AFAFIIAE_02011	1.62e-105	terS	-	-	L	-	-	-	Phage terminase, small subunit
AFAFIIAE_02012	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
AFAFIIAE_02013	6.27e-31	-	-	-	-	-	-	-	-
AFAFIIAE_02014	1.07e-281	-	-	-	S	-	-	-	Phage portal protein
AFAFIIAE_02015	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
AFAFIIAE_02016	2.28e-63	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
AFAFIIAE_02017	6.83e-18	-	-	-	S	-	-	-	Phage head-tail joining protein
AFAFIIAE_02018	2.3e-23	-	-	-	-	-	-	-	-
AFAFIIAE_02019	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
AFAFIIAE_02021	1.87e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFAFIIAE_02022	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
AFAFIIAE_02023	2.16e-238	lipA	-	-	I	-	-	-	Carboxylesterase family
AFAFIIAE_02024	4.83e-170	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AFAFIIAE_02025	2.52e-169	epsB	-	-	M	-	-	-	biosynthesis protein
AFAFIIAE_02026	2.92e-143	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
AFAFIIAE_02027	6.04e-250	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
AFAFIIAE_02028	2.1e-264	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
AFAFIIAE_02029	5.77e-115	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
AFAFIIAE_02030	3.79e-89	-	-	-	S	-	-	-	Glycosyltransferase like family 2
AFAFIIAE_02031	9.22e-49	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
AFAFIIAE_02032	1.22e-83	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
AFAFIIAE_02034	4.11e-78	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
AFAFIIAE_02036	3.52e-176	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AFAFIIAE_02037	6.02e-216	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFAFIIAE_02038	1.83e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AFAFIIAE_02039	4.4e-116	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AFAFIIAE_02040	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AFAFIIAE_02041	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
AFAFIIAE_02042	5.96e-240	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AFAFIIAE_02043	9.67e-250	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AFAFIIAE_02044	8.13e-82	-	-	-	-	-	-	-	-
AFAFIIAE_02045	1.35e-97	-	-	-	L	-	-	-	NUDIX domain
AFAFIIAE_02046	1.54e-25	-	-	-	EG	-	-	-	EamA-like transporter family
AFAFIIAE_02047	9.64e-135	-	-	-	EG	-	-	-	EamA-like transporter family
AFAFIIAE_02048	2.34e-140	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
AFAFIIAE_02049	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
AFAFIIAE_02051	8.91e-306	-	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_02052	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
AFAFIIAE_02053	5.44e-100	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
AFAFIIAE_02054	1.08e-54	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
AFAFIIAE_02055	1.35e-71	ps105	-	-	-	-	-	-	-
AFAFIIAE_02057	1.48e-106	kdgR	-	-	K	-	-	-	FCD domain
AFAFIIAE_02060	1.87e-191	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
AFAFIIAE_02061	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
AFAFIIAE_02062	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_02063	9.71e-127	-	-	-	K	-	-	-	transcriptional regulator
AFAFIIAE_02064	4.35e-197	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
AFAFIIAE_02065	4.05e-64	-	-	-	-	-	-	-	-
AFAFIIAE_02068	9.07e-166	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
AFAFIIAE_02069	1.86e-269	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
AFAFIIAE_02070	1.32e-51	-	-	-	-	-	-	-	-
AFAFIIAE_02071	1.23e-221	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
AFAFIIAE_02072	7.14e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFAFIIAE_02073	1.05e-273	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
AFAFIIAE_02074	3.6e-67	-	-	-	-	-	-	-	-
AFAFIIAE_02075	2.21e-164	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
AFAFIIAE_02076	1.62e-93	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
AFAFIIAE_02077	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
AFAFIIAE_02079	9.19e-249	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AFAFIIAE_02080	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AFAFIIAE_02081	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
AFAFIIAE_02082	1.48e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
AFAFIIAE_02083	6.52e-115	sip	-	-	L	-	-	-	Phage integrase family
AFAFIIAE_02084	2.58e-113	sip	-	-	L	-	-	-	Phage integrase family
AFAFIIAE_02087	6.97e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
AFAFIIAE_02088	8.19e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
AFAFIIAE_02089	3.84e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AFAFIIAE_02091	1.84e-282	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
AFAFIIAE_02092	1.12e-67	-	-	-	-	-	-	-	-
AFAFIIAE_02094	7.5e-53	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AFAFIIAE_02095	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
AFAFIIAE_02096	6.62e-143	-	-	-	S	-	-	-	Membrane
AFAFIIAE_02097	4.32e-133	-	-	-	-	-	-	-	-
AFAFIIAE_02098	5.14e-217	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
AFAFIIAE_02099	5.32e-145	-	-	-	Q	-	-	-	Methyltransferase
AFAFIIAE_02100	2.16e-68	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
AFAFIIAE_02101	1.5e-171	-	-	-	S	-	-	-	-acetyltransferase
AFAFIIAE_02102	3.92e-120	yfbM	-	-	K	-	-	-	FR47-like protein
AFAFIIAE_02103	2.42e-122	-	-	-	E	-	-	-	HAD-hyrolase-like
AFAFIIAE_02104	5.29e-239	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
AFAFIIAE_02105	1.33e-178	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
AFAFIIAE_02106	3.86e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AFAFIIAE_02107	2.62e-106	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
AFAFIIAE_02108	1.34e-98	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
AFAFIIAE_02109	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AFAFIIAE_02110	2.57e-252	ysdE	-	-	P	-	-	-	Citrate transporter
AFAFIIAE_02111	1.23e-90	-	-	-	-	-	-	-	-
AFAFIIAE_02112	2.51e-290	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
AFAFIIAE_02113	8.15e-293	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
AFAFIIAE_02114	3.03e-58	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
AFAFIIAE_02115	1.43e-133	-	-	-	-	-	-	-	-
AFAFIIAE_02116	0.0	cadA	-	-	P	-	-	-	P-type ATPase
AFAFIIAE_02117	1.48e-98	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
AFAFIIAE_02118	2.35e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
AFAFIIAE_02119	1.14e-282	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
AFAFIIAE_02120	1.24e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
AFAFIIAE_02121	1.05e-182	yycI	-	-	S	-	-	-	YycH protein
AFAFIIAE_02122	0.0	yycH	-	-	S	-	-	-	YycH protein
AFAFIIAE_02123	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
AFAFIIAE_02124	3.03e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
AFAFIIAE_02125	5.03e-156	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
AFAFIIAE_02126	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
AFAFIIAE_02127	1.63e-298	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
AFAFIIAE_02128	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
AFAFIIAE_02129	7.93e-272	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
AFAFIIAE_02130	9.09e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
AFAFIIAE_02131	1.76e-298	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFAFIIAE_02132	1.97e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
AFAFIIAE_02133	3.39e-67	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
AFAFIIAE_02134	8.36e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
AFAFIIAE_02135	3.03e-139	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
AFAFIIAE_02136	1.84e-110	-	-	-	F	-	-	-	NUDIX domain
AFAFIIAE_02137	3.71e-117	-	-	-	S	-	-	-	AAA domain
AFAFIIAE_02138	3.32e-148	ycaC	-	-	Q	-	-	-	Isochorismatase family
AFAFIIAE_02139	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
AFAFIIAE_02140	5.62e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
AFAFIIAE_02141	2.11e-220	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
AFAFIIAE_02142	1.08e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
AFAFIIAE_02143	1.73e-216	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
AFAFIIAE_02144	1.57e-171	manM	-	-	G	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
AFAFIIAE_02145	4.14e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
AFAFIIAE_02146	9.77e-279	-	-	-	EGP	-	-	-	Major facilitator Superfamily
AFAFIIAE_02147	7.28e-243	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
AFAFIIAE_02148	8.33e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AFAFIIAE_02149	3.06e-204	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
AFAFIIAE_02151	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AFAFIIAE_02152	3.81e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_02153	4.51e-41	-	-	-	-	-	-	-	-
AFAFIIAE_02154	1.21e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
AFAFIIAE_02155	1.33e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
AFAFIIAE_02156	5.96e-53	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
AFAFIIAE_02157	1.4e-69	-	-	-	-	-	-	-	-
AFAFIIAE_02158	8.68e-106	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
AFAFIIAE_02159	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
AFAFIIAE_02160	7.76e-186	-	-	-	S	-	-	-	AAA ATPase domain
AFAFIIAE_02161	1.08e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
AFAFIIAE_02162	1.09e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_02163	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_02164	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AFAFIIAE_02165	9.37e-129	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
AFAFIIAE_02166	9.04e-137	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
AFAFIIAE_02167	2.12e-181	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
AFAFIIAE_02168	8.74e-235	-	-	-	S	-	-	-	Protein of unknown function DUF58
AFAFIIAE_02169	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
AFAFIIAE_02170	2.11e-273	-	-	-	M	-	-	-	Glycosyl transferases group 1
AFAFIIAE_02171	1.34e-126	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
AFAFIIAE_02172	7.14e-185	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
AFAFIIAE_02173	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
AFAFIIAE_02174	8.26e-147	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
AFAFIIAE_02175	1.49e-61	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
AFAFIIAE_02176	3.65e-272	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
AFAFIIAE_02177	5.39e-292	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
AFAFIIAE_02178	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
AFAFIIAE_02179	1.74e-154	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
AFAFIIAE_02180	1.56e-194	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
AFAFIIAE_02181	1.3e-115	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
AFAFIIAE_02182	6.42e-86	-	-	-	-	-	-	-	-
AFAFIIAE_02183	1.58e-284	yagE	-	-	E	-	-	-	Amino acid permease
AFAFIIAE_02184	2.36e-217	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AFAFIIAE_02185	3.5e-88	-	-	-	V	-	-	-	Domain of unknown function (DUF3883)
AFAFIIAE_02186	3.99e-198	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
AFAFIIAE_02187	5.84e-187	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
AFAFIIAE_02189	4.4e-47	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
AFAFIIAE_02190	5.74e-207	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
AFAFIIAE_02191	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
AFAFIIAE_02192	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
AFAFIIAE_02193	6.02e-85	-	-	-	S	-	-	-	Domain of unknown function DUF1829
AFAFIIAE_02194	5.22e-63	-	-	-	S	-	-	-	Domain of unknown function DUF1829
AFAFIIAE_02195	1.18e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
AFAFIIAE_02197	7.72e-194	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
AFAFIIAE_02198	4.8e-104	-	-	-	S	-	-	-	Pfam Transposase IS66
AFAFIIAE_02199	2.27e-293	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
AFAFIIAE_02200	2.56e-219	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
AFAFIIAE_02201	5.68e-110	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
AFAFIIAE_02203	1.4e-58	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
AFAFIIAE_02204	3.41e-91	-	-	-	S	-	-	-	COG0433 Predicted ATPase
AFAFIIAE_02205	5.87e-226	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	cysteine-type peptidase activity
AFAFIIAE_02211	9.85e-05	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
AFAFIIAE_02213	3.2e-284	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
AFAFIIAE_02215	9.26e-233	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
AFAFIIAE_02216	1.04e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
AFAFIIAE_02217	1.34e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
AFAFIIAE_02218	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
AFAFIIAE_02219	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFAFIIAE_02220	4.18e-151	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
AFAFIIAE_02221	2.45e-264	-	-	-	L	-	-	-	Transposase DDE domain
AFAFIIAE_02222	4.21e-53	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
AFAFIIAE_02223	1.55e-273	-	-	-	G	-	-	-	Transporter, major facilitator family protein
AFAFIIAE_02224	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
AFAFIIAE_02225	4.9e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AFAFIIAE_02226	3.41e-68	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
AFAFIIAE_02227	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
AFAFIIAE_02228	2.39e-98	-	-	-	L	-	-	-	Initiator Replication protein
AFAFIIAE_02229	1.23e-38	-	-	-	-	-	-	-	-
AFAFIIAE_02231	1.22e-32	-	-	-	-	-	-	-	-
AFAFIIAE_02232	2.54e-32	-	-	-	-	-	-	-	-
AFAFIIAE_02233	5.36e-13	-	-	-	-	-	-	-	-
AFAFIIAE_02234	1.52e-72	-	-	-	-	-	-	-	-
AFAFIIAE_02236	1.21e-182	-	-	-	S	-	-	-	CAAX protease self-immunity
AFAFIIAE_02240	1.27e-15	-	-	-	-	-	-	-	-
AFAFIIAE_02242	7.99e-184	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
AFAFIIAE_02243	6.6e-165	-	2.7.13.3	-	T	ko:K02476,ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
AFAFIIAE_02245	5.04e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
AFAFIIAE_02246	2.21e-181	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFAFIIAE_02247	9.74e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AFAFIIAE_02248	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
AFAFIIAE_02249	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
AFAFIIAE_02250	2.65e-139	-	-	-	-	-	-	-	-
AFAFIIAE_02251	7.54e-92	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
AFAFIIAE_02252	5.06e-195	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
AFAFIIAE_02253	1.78e-11	-	-	-	-	-	-	-	-
AFAFIIAE_02254	1.09e-47	-	-	-	-	-	-	-	-
AFAFIIAE_02255	1.47e-33	-	-	-	-	-	-	-	-
AFAFIIAE_02256	3.66e-18	-	-	-	-	-	-	-	-
AFAFIIAE_02257	1.19e-41	-	-	-	-	-	-	-	-
AFAFIIAE_02258	2.26e-50	-	-	-	-	-	-	-	-
AFAFIIAE_02259	2.32e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
AFAFIIAE_02260	1.11e-283	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AFAFIIAE_02264	8.74e-161	-	-	-	H	-	-	-	Pfam:Transaldolase
AFAFIIAE_02265	9.11e-84	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
AFAFIIAE_02266	2.82e-259	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
AFAFIIAE_02267	2.36e-130	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
AFAFIIAE_02268	2.16e-114	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
AFAFIIAE_02269	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
AFAFIIAE_02270	1.68e-184	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
AFAFIIAE_02271	9.27e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
AFAFIIAE_02272	2.6e-232	-	-	-	K	-	-	-	LysR substrate binding domain
AFAFIIAE_02273	1.34e-175	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AFAFIIAE_02274	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
AFAFIIAE_02275	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFAFIIAE_02276	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFAFIIAE_02277	6.92e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AFAFIIAE_02278	5.38e-219	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
AFAFIIAE_02279	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AFAFIIAE_02280	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AFAFIIAE_02281	1.66e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
AFAFIIAE_02282	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AFAFIIAE_02283	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFAFIIAE_02284	1.82e-186	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
AFAFIIAE_02285	2.05e-178	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFAFIIAE_02286	1.46e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AFAFIIAE_02287	8.99e-64	-	-	-	K	-	-	-	Helix-turn-helix domain
AFAFIIAE_02288	4.3e-316	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
AFAFIIAE_02289	1.03e-54	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
AFAFIIAE_02290	6.11e-111	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AFAFIIAE_02291	3.18e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
AFAFIIAE_02292	2.31e-194	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
AFAFIIAE_02293	4.9e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
AFAFIIAE_02294	5.26e-148	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
AFAFIIAE_02295	3.64e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AFAFIIAE_02296	2.43e-243	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFAFIIAE_02297	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_02298	2.95e-110	-	-	-	-	-	-	-	-
AFAFIIAE_02299	5.31e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFAFIIAE_02300	8.71e-200	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFAFIIAE_02301	4.36e-302	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
AFAFIIAE_02302	1.2e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFAFIIAE_02303	8.65e-311	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
AFAFIIAE_02304	1.72e-303	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
AFAFIIAE_02305	2.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
AFAFIIAE_02306	1.68e-104	-	-	-	M	-	-	-	Lysin motif
AFAFIIAE_02307	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
AFAFIIAE_02308	2.14e-233	-	-	-	S	-	-	-	Helix-turn-helix domain
AFAFIIAE_02309	1.92e-59	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
AFAFIIAE_02310	4.35e-123	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AFAFIIAE_02311	3.15e-175	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
AFAFIIAE_02312	8.74e-139	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AFAFIIAE_02313	1.07e-159	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AFAFIIAE_02314	1.59e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFAFIIAE_02315	9.95e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
AFAFIIAE_02316	5.96e-207	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
AFAFIIAE_02317	4.31e-95	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
AFAFIIAE_02318	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
AFAFIIAE_02319	2.21e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AFAFIIAE_02320	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
AFAFIIAE_02321	8.1e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
AFAFIIAE_02322	4.99e-184	-	-	-	-	-	-	-	-
AFAFIIAE_02323	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
AFAFIIAE_02324	6.3e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
AFAFIIAE_02325	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
AFAFIIAE_02326	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AFAFIIAE_02327	4.1e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
AFAFIIAE_02328	1.83e-183	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
AFAFIIAE_02329	2.71e-233	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AFAFIIAE_02330	0.0	oatA	-	-	I	-	-	-	Acyltransferase
AFAFIIAE_02331	3.37e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFAFIIAE_02332	2.78e-170	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
AFAFIIAE_02333	2.76e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AFAFIIAE_02334	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
AFAFIIAE_02335	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AFAFIIAE_02336	1.89e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_02337	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
AFAFIIAE_02338	3.33e-28	-	-	-	-	-	-	-	-
AFAFIIAE_02339	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
AFAFIIAE_02340	2.74e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
AFAFIIAE_02341	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AFAFIIAE_02342	9.55e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AFAFIIAE_02343	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
AFAFIIAE_02344	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AFAFIIAE_02345	1.93e-213	-	-	-	S	-	-	-	Tetratricopeptide repeat
AFAFIIAE_02346	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFAFIIAE_02347	5.41e-62	-	-	-	-	-	-	-	-
AFAFIIAE_02348	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AFAFIIAE_02350	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
AFAFIIAE_02351	5.08e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
AFAFIIAE_02352	7.21e-245	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
AFAFIIAE_02353	5.45e-49	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
AFAFIIAE_02354	5.07e-123	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
AFAFIIAE_02355	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
AFAFIIAE_02356	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
AFAFIIAE_02357	1.1e-22	ORF00048	-	-	-	-	-	-	-
AFAFIIAE_02358	3.62e-168	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
AFAFIIAE_02359	1.5e-44	-	-	-	-	-	-	-	-
AFAFIIAE_02360	7.4e-164	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
AFAFIIAE_02361	1.06e-237	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
AFAFIIAE_02362	3.44e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AFAFIIAE_02363	2.98e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AFAFIIAE_02364	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
AFAFIIAE_02365	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
AFAFIIAE_02366	2.34e-287	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
AFAFIIAE_02367	5.84e-64	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
AFAFIIAE_02369	9.96e-212	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
AFAFIIAE_02370	2.05e-277	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
AFAFIIAE_02371	6.81e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
AFAFIIAE_02372	9.19e-209	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_02373	8.67e-143	-	-	-	I	-	-	-	ABC-2 family transporter protein
AFAFIIAE_02374	2.06e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
AFAFIIAE_02375	2.07e-282	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
AFAFIIAE_02376	2.95e-68	ohr	-	-	O	-	-	-	redox protein regulator of disulfide bond formation
AFAFIIAE_02377	7.36e-156	-	-	-	-	-	-	-	-
AFAFIIAE_02378	2e-73	-	-	-	M	-	-	-	Glycosyl transferases group 1
AFAFIIAE_02379	1.6e-30	-	-	-	M	-	-	-	Glycosyl transferases group 1
AFAFIIAE_02380	1.07e-69	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
AFAFIIAE_02381	2.65e-67	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
AFAFIIAE_02382	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
AFAFIIAE_02383	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
AFAFIIAE_02384	7.26e-208	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
AFAFIIAE_02385	1.92e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFAFIIAE_02386	6.57e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
AFAFIIAE_02387	1.51e-206	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
AFAFIIAE_02388	2.21e-258	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
AFAFIIAE_02390	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
AFAFIIAE_02391	4.36e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
AFAFIIAE_02392	1.04e-269	yttB	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_02393	1.53e-19	-	-	-	-	-	-	-	-
AFAFIIAE_02394	6.05e-103	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
AFAFIIAE_02395	3.38e-128	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
AFAFIIAE_02396	1.28e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
AFAFIIAE_02397	2.26e-212	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
AFAFIIAE_02399	6.99e-130	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
AFAFIIAE_02400	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
AFAFIIAE_02401	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
AFAFIIAE_02402	4.99e-163	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
AFAFIIAE_02403	1.39e-173	ypaC	-	-	Q	-	-	-	Methyltransferase domain
AFAFIIAE_02404	0.0	-	-	-	S	-	-	-	ABC transporter
AFAFIIAE_02405	1.05e-222	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
AFAFIIAE_02406	1.26e-139	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
AFAFIIAE_02407	4.42e-54	-	-	-	-	-	-	-	-
AFAFIIAE_02408	2.19e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
AFAFIIAE_02409	2.32e-188	-	-	-	M	-	-	-	Glycosyltransferase like family 2
AFAFIIAE_02410	1.55e-173	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
AFAFIIAE_02411	3.46e-103	-	-	-	T	-	-	-	Sh3 type 3 domain protein
AFAFIIAE_02412	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
AFAFIIAE_02413	4.84e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
AFAFIIAE_02414	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
AFAFIIAE_02415	1.07e-205	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
AFAFIIAE_02416	2.55e-212	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
AFAFIIAE_02417	6.97e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
AFAFIIAE_02418	9.72e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
AFAFIIAE_02419	3.74e-75	-	-	-	-	-	-	-	-
AFAFIIAE_02420	3.01e-252	-	-	-	S	-	-	-	Protein conserved in bacteria
AFAFIIAE_02421	1.07e-206	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
AFAFIIAE_02422	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
AFAFIIAE_02423	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
AFAFIIAE_02424	2.72e-190	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
AFAFIIAE_02425	1.35e-204	-	-	-	S	-	-	-	Glycosyltransferase like family 2
AFAFIIAE_02426	7.26e-163	welB	-	-	S	-	-	-	Glycosyltransferase like family 2
AFAFIIAE_02427	6.41e-196	-	-	-	S	-	-	-	Glycosyl transferase family 2
AFAFIIAE_02428	6.99e-314	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
AFAFIIAE_02429	6.55e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
AFAFIIAE_02430	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
AFAFIIAE_02431	1.73e-215	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
AFAFIIAE_02432	1.27e-186	gntR	-	-	K	-	-	-	rpiR family
AFAFIIAE_02433	8.2e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
AFAFIIAE_02434	2.71e-182	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
AFAFIIAE_02435	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AFAFIIAE_02436	2.06e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFAFIIAE_02437	2.75e-303	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
AFAFIIAE_02438	2.81e-278	hpk31	-	-	T	-	-	-	Histidine kinase
AFAFIIAE_02439	1.68e-156	vanR	-	-	K	-	-	-	response regulator
AFAFIIAE_02440	1.18e-155	-	-	-	-	-	-	-	-
AFAFIIAE_02441	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AFAFIIAE_02442	7.12e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
AFAFIIAE_02443	9.76e-237	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AFAFIIAE_02444	3.26e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
AFAFIIAE_02445	1.11e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
AFAFIIAE_02446	1.49e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
AFAFIIAE_02447	6.56e-187	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
AFAFIIAE_02448	2.27e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
AFAFIIAE_02449	4.01e-87	-	-	-	-	-	-	-	-
AFAFIIAE_02450	1.35e-164	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
AFAFIIAE_02451	6.15e-139	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
AFAFIIAE_02452	5.7e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AFAFIIAE_02453	1.16e-194	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
AFAFIIAE_02454	1.08e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
AFAFIIAE_02456	1.97e-92	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
AFAFIIAE_02457	8.12e-90	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
AFAFIIAE_02458	4.15e-34	-	-	-	-	-	-	-	-
AFAFIIAE_02459	1.16e-112	-	-	-	S	-	-	-	Protein conserved in bacteria
AFAFIIAE_02460	4.95e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
AFAFIIAE_02461	2.27e-94	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
AFAFIIAE_02462	2.86e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFAFIIAE_02463	2.82e-36	-	-	-	-	-	-	-	-
AFAFIIAE_02464	5.54e-50	-	-	-	-	-	-	-	-
AFAFIIAE_02465	1.63e-109	-	-	-	C	-	-	-	Flavodoxin
AFAFIIAE_02466	4.85e-65	-	-	-	-	-	-	-	-
AFAFIIAE_02467	5.12e-117	-	-	-	-	-	-	-	-
AFAFIIAE_02468	1.47e-07	-	-	-	-	-	-	-	-
AFAFIIAE_02469	6.45e-74	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
AFAFIIAE_02470	8.76e-178	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
AFAFIIAE_02471	2.97e-287	-	-	-	S	ko:K06872	-	ko00000	TPM domain
AFAFIIAE_02472	6.18e-150	-	-	-	-	-	-	-	-
AFAFIIAE_02473	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
AFAFIIAE_02474	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
AFAFIIAE_02475	3.59e-141	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
AFAFIIAE_02476	3.19e-176	-	-	-	V	-	-	-	ABC transporter transmembrane region
AFAFIIAE_02477	8.88e-100	-	-	-	V	-	-	-	ABC transporter transmembrane region
AFAFIIAE_02478	7.38e-274	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
AFAFIIAE_02479	1.39e-101	-	-	-	S	-	-	-	NUDIX domain
AFAFIIAE_02480	1.91e-56	-	-	-	-	-	-	-	-
AFAFIIAE_02481	4.91e-115	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
AFAFIIAE_02482	5.54e-91	-	-	-	-	-	-	-	-
AFAFIIAE_02483	7.36e-67	-	-	-	-	-	-	-	-
AFAFIIAE_02484	1.35e-129	-	-	-	-	-	-	-	-
AFAFIIAE_02485	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
AFAFIIAE_02486	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
AFAFIIAE_02488	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_02490	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
AFAFIIAE_02491	1.45e-46	-	-	-	-	-	-	-	-
AFAFIIAE_02493	2.76e-104	-	-	-	-	-	-	-	-
AFAFIIAE_02496	1.23e-171	-	-	-	-	-	-	-	-
AFAFIIAE_02497	3.38e-30	-	-	-	-	-	-	-	-
AFAFIIAE_02498	3.59e-165	-	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
AFAFIIAE_02499	6.31e-125	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
AFAFIIAE_02500	6.35e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AFAFIIAE_02501	2.86e-108	uspA	-	-	T	-	-	-	universal stress protein
AFAFIIAE_02502	1.65e-52	-	-	-	-	-	-	-	-
AFAFIIAE_02504	1.37e-305	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
AFAFIIAE_02506	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
AFAFIIAE_02507	4.09e-131	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AFAFIIAE_02508	4.57e-69	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
AFAFIIAE_02513	4.14e-41	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
AFAFIIAE_02514	3.24e-05	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
AFAFIIAE_02515	1.5e-75	-	-	-	P	-	-	-	ABC-2 family transporter protein
AFAFIIAE_02517	2.03e-73	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
AFAFIIAE_02518	1.13e-87	-	-	-	K	-	-	-	Tetracyclin repressor, C-terminal all-alpha domain
AFAFIIAE_02520	1.57e-96	-	-	-	S	-	-	-	Phospholipase A2
AFAFIIAE_02522	5.45e-146	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
AFAFIIAE_02523	7.16e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AFAFIIAE_02524	2.45e-61	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AFAFIIAE_02526	5.24e-66	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
AFAFIIAE_02527	2.67e-121	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
AFAFIIAE_02528	1.4e-14	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
AFAFIIAE_02529	2.25e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
AFAFIIAE_02530	1.05e-65	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
AFAFIIAE_02533	0.0	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
AFAFIIAE_02535	1.06e-165	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
AFAFIIAE_02537	4.26e-14	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
AFAFIIAE_02538	1.57e-299	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
AFAFIIAE_02539	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
AFAFIIAE_02540	1.12e-128	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AFAFIIAE_02541	3.28e-233	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
AFAFIIAE_02542	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AFAFIIAE_02543	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFAFIIAE_02544	1.39e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFAFIIAE_02545	8.48e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFAFIIAE_02546	1.63e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
AFAFIIAE_02547	1e-272	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AFAFIIAE_02548	2.66e-102	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AFAFIIAE_02549	3.87e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
AFAFIIAE_02550	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
AFAFIIAE_02551	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AFAFIIAE_02552	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
AFAFIIAE_02553	3.88e-38	-	-	-	-	-	-	-	-
AFAFIIAE_02554	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
AFAFIIAE_02555	3.36e-61	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
AFAFIIAE_02557	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AFAFIIAE_02558	1.18e-310	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
AFAFIIAE_02559	4.17e-262	yueF	-	-	S	-	-	-	AI-2E family transporter
AFAFIIAE_02560	4.61e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
AFAFIIAE_02561	3.88e-123	-	-	-	-	-	-	-	-
AFAFIIAE_02562	1.1e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
AFAFIIAE_02563	7.99e-182	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
AFAFIIAE_02564	0.0	frvR	-	-	K	ko:K02538,ko:K03483,ko:K09685,ko:K18531	-	ko00000,ko03000	transcriptional antiterminator
AFAFIIAE_02565	1.52e-81	-	-	-	-	-	-	-	-
AFAFIIAE_02566	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFAFIIAE_02567	1.68e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
AFAFIIAE_02568	2.13e-172	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
AFAFIIAE_02569	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
AFAFIIAE_02570	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFAFIIAE_02571	2.36e-111	-	-	-	-	-	-	-	-
AFAFIIAE_02572	7.89e-66	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
AFAFIIAE_02573	6.27e-67	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
AFAFIIAE_02574	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
AFAFIIAE_02575	2.6e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
AFAFIIAE_02576	4.66e-267	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
AFAFIIAE_02577	1.35e-263	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
AFAFIIAE_02578	7.23e-66	-	-	-	-	-	-	-	-
AFAFIIAE_02579	5.75e-206	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
AFAFIIAE_02580	6.06e-132	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
AFAFIIAE_02581	2.25e-201	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	converts alpha-aldose to the beta-anomer
AFAFIIAE_02582	1.8e-270	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
AFAFIIAE_02583	4.33e-132	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
AFAFIIAE_02585	4e-105	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
AFAFIIAE_02586	1.65e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
AFAFIIAE_02587	3.35e-167	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_02588	4.02e-188	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
AFAFIIAE_02589	2.03e-197	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
AFAFIIAE_02590	2.77e-94	-	-	-	-	-	-	-	-
AFAFIIAE_02591	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
AFAFIIAE_02592	6.59e-276	-	-	-	V	-	-	-	Beta-lactamase
AFAFIIAE_02593	2.51e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AFAFIIAE_02594	6.4e-280	-	-	-	V	-	-	-	Beta-lactamase
AFAFIIAE_02595	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AFAFIIAE_02596	1.62e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
AFAFIIAE_02597	8.7e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AFAFIIAE_02598	1.13e-177	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFAFIIAE_02599	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
AFAFIIAE_02602	2.96e-203	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
AFAFIIAE_02603	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
AFAFIIAE_02604	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_02605	1.71e-87	-	-	-	-	-	-	-	-
AFAFIIAE_02606	6.13e-100	-	-	-	S	-	-	-	function, without similarity to other proteins
AFAFIIAE_02607	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
AFAFIIAE_02608	3.08e-291	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
AFAFIIAE_02609	8.15e-77	-	-	-	-	-	-	-	-
AFAFIIAE_02610	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
AFAFIIAE_02611	6.28e-25	-	-	-	S	-	-	-	Virus attachment protein p12 family
AFAFIIAE_02612	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
AFAFIIAE_02613	4.14e-91	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
AFAFIIAE_02614	4.77e-167	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
AFAFIIAE_02617	2.51e-150	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
AFAFIIAE_02618	3.31e-78	-	-	-	S	-	-	-	MucBP domain
AFAFIIAE_02619	9.73e-109	-	-	-	-	-	-	-	-
AFAFIIAE_02621	1.4e-315	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
AFAFIIAE_02622	3.51e-224	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
AFAFIIAE_02623	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AFAFIIAE_02624	1.98e-50	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
AFAFIIAE_02625	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
AFAFIIAE_02626	2.58e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
AFAFIIAE_02627	1.98e-38	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
AFAFIIAE_02628	8.57e-309	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
AFAFIIAE_02629	2.73e-140	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
AFAFIIAE_02630	7.33e-210	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AFAFIIAE_02631	4.97e-93	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
AFAFIIAE_02632	9.31e-56	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
AFAFIIAE_02633	1.19e-192	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
AFAFIIAE_02634	3.53e-76	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
AFAFIIAE_02635	1.32e-111	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
AFAFIIAE_02636	1.05e-92	-	-	-	K	-	-	-	DeoR C terminal sensor domain
AFAFIIAE_02637	1.17e-54	-	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
AFAFIIAE_02638	1.23e-148	-	-	-	P	-	-	-	Major Facilitator Superfamily
AFAFIIAE_02640	1.16e-14	-	-	-	-	-	-	-	-
AFAFIIAE_02641	8.2e-102	-	-	-	-	-	-	-	-
AFAFIIAE_02643	1.08e-102	-	-	-	-	-	-	-	-
AFAFIIAE_02644	2.45e-23	-	-	-	-	-	-	-	-
AFAFIIAE_02645	1.18e-85	-	-	-	-	-	-	-	-
AFAFIIAE_02646	2.01e-56	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
AFAFIIAE_02647	2.76e-36	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
AFAFIIAE_02648	3.95e-221	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AFAFIIAE_02649	1.15e-161	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
AFAFIIAE_02650	3.62e-18	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
AFAFIIAE_02651	5.23e-36	-	-	-	-	-	-	-	-
AFAFIIAE_02652	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AFAFIIAE_02653	1.87e-49	-	-	-	L	-	-	-	Transposase DDE domain
AFAFIIAE_02654	2.71e-98	-	-	-	M	-	-	-	Glycosyltransferase like family 2
AFAFIIAE_02655	4.57e-87	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
AFAFIIAE_02656	5.01e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
AFAFIIAE_02657	4.95e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AFAFIIAE_02658	1.24e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AFAFIIAE_02659	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AFAFIIAE_02660	5.15e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
AFAFIIAE_02661	1.34e-146	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
AFAFIIAE_02662	1.97e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
AFAFIIAE_02663	4.82e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
AFAFIIAE_02664	1.88e-191	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
AFAFIIAE_02665	8.66e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
AFAFIIAE_02666	2.69e-148	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
AFAFIIAE_02667	8.63e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
AFAFIIAE_02668	9.66e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
AFAFIIAE_02669	2.7e-145	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
AFAFIIAE_02670	2.71e-192	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
AFAFIIAE_02671	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFAFIIAE_02672	7.11e-60	-	-	-	-	-	-	-	-
AFAFIIAE_02673	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
AFAFIIAE_02674	2.76e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AFAFIIAE_02675	2.65e-67	ftsL	-	-	D	-	-	-	cell division protein FtsL
AFAFIIAE_02676	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
AFAFIIAE_02677	5.4e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AFAFIIAE_02678	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AFAFIIAE_02679	4e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AFAFIIAE_02680	2.06e-200	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AFAFIIAE_02681	1.44e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AFAFIIAE_02682	6.55e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFAFIIAE_02683	7.24e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AFAFIIAE_02684	5.58e-60	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	integral membrane protein
AFAFIIAE_02685	2.4e-185	ylmH	-	-	S	-	-	-	S4 domain protein
AFAFIIAE_02686	1.71e-119	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
AFAFIIAE_02687	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AFAFIIAE_02688	4.62e-48	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
AFAFIIAE_02689	5.93e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
AFAFIIAE_02690	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
AFAFIIAE_02691	7.29e-270	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
AFAFIIAE_02692	8.03e-151	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AFAFIIAE_02693	1.83e-124	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
AFAFIIAE_02694	2.45e-40	-	-	-	-	-	-	-	-
AFAFIIAE_02695	1.95e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AFAFIIAE_02696	2.81e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
AFAFIIAE_02697	2.45e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
AFAFIIAE_02698	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
AFAFIIAE_02699	7.55e-311	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AFAFIIAE_02700	4.69e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
AFAFIIAE_02701	1.62e-151	-	-	-	S	-	-	-	repeat protein
AFAFIIAE_02702	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AFAFIIAE_02703	2.86e-312	-	-	-	S	-	-	-	Sterol carrier protein domain
AFAFIIAE_02704	4.67e-232	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
AFAFIIAE_02705	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFAFIIAE_02706	2.02e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
AFAFIIAE_02707	1.3e-94	-	-	-	-	-	-	-	-
AFAFIIAE_02708	1.73e-63	-	-	-	-	-	-	-	-
AFAFIIAE_02709	4.82e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFAFIIAE_02710	1.7e-110	-	-	-	S	-	-	-	E1-E2 ATPase
AFAFIIAE_02711	1.42e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
AFAFIIAE_02712	1.15e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
AFAFIIAE_02713	0.0	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFAFIIAE_02714	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
AFAFIIAE_02715	4.32e-202	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
AFAFIIAE_02716	6.15e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
AFAFIIAE_02717	3.56e-189	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
AFAFIIAE_02718	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
AFAFIIAE_02719	1.66e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
AFAFIIAE_02720	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AFAFIIAE_02721	8.46e-84	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
AFAFIIAE_02722	9.93e-130	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
AFAFIIAE_02723	4.38e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AFAFIIAE_02724	1.82e-233	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
AFAFIIAE_02725	4.95e-146	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
AFAFIIAE_02726	1.39e-246	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
AFAFIIAE_02727	4.75e-89	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family