ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KPMDMHFH_00001 1.9e-132 cadD - - P - - - cadmium resistance
KPMDMHFH_00002 3.11e-73 cadX - - K ko:K21903 - ko00000,ko03000 Bacterial regulatory protein, arsR family
KPMDMHFH_00003 2.36e-215 int - - L - - - Belongs to the 'phage' integrase family
KPMDMHFH_00004 3.78e-20 - - - S - - - Helix-turn-helix domain
KPMDMHFH_00005 4.37e-223 - - - S - - - Septin
KPMDMHFH_00006 1.27e-15 - - - - - - - -
KPMDMHFH_00007 4.52e-37 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
KPMDMHFH_00008 5.53e-119 - - - K - - - Replication initiation factor
KPMDMHFH_00009 3.25e-102 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
KPMDMHFH_00010 3.87e-164 lacR - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
KPMDMHFH_00011 8.35e-94 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
KPMDMHFH_00012 4.91e-121 lacB 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
KPMDMHFH_00013 1.97e-229 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
KPMDMHFH_00014 1.66e-67 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
KPMDMHFH_00015 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KPMDMHFH_00016 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPMDMHFH_00017 2.55e-216 lacX - - G - - - Aldose 1-epimerase
KPMDMHFH_00018 6.8e-128 - - - K - - - Rhodanese Homology Domain
KPMDMHFH_00019 4.63e-62 - - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KPMDMHFH_00020 1.39e-203 trxB1 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KPMDMHFH_00022 3.94e-65 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
KPMDMHFH_00024 1.73e-19 - - - S - - - Protein of unknown function (DUF1211)
KPMDMHFH_00025 3.08e-198 - - - L ko:K07497 - ko00000 Integrase core domain protein
KPMDMHFH_00026 1.14e-157 - - - L - - - Helix-turn-helix domain
KPMDMHFH_00028 3.02e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
KPMDMHFH_00030 6.12e-193 srtB - - S - - - Sortase family
KPMDMHFH_00031 3e-295 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
KPMDMHFH_00032 3.56e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
KPMDMHFH_00033 4.26e-307 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
KPMDMHFH_00034 4.85e-168 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase
KPMDMHFH_00035 1.08e-175 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KPMDMHFH_00036 4.75e-132 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Muramidase (Flagellum-specific)
KPMDMHFH_00037 8.1e-238 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KPMDMHFH_00038 6.99e-105 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KPMDMHFH_00039 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KPMDMHFH_00041 6.04e-252 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KPMDMHFH_00042 2.14e-178 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KPMDMHFH_00043 5e-175 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
KPMDMHFH_00044 2.05e-104 hmpT - - S - - - cog cog4720
KPMDMHFH_00045 0.0 - - - P - - - p-ATPase superfamily P-type ATPase copper transporter
KPMDMHFH_00046 4.93e-54 - - - - - - - -
KPMDMHFH_00047 1.87e-138 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KPMDMHFH_00048 6.9e-102 - - - S - - - membrane protein of uknown function UCP014873
KPMDMHFH_00049 3.54e-43 int - - L - - - DNA integration
KPMDMHFH_00050 2.12e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KPMDMHFH_00051 1.42e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPMDMHFH_00052 1.21e-40 - - - K ko:K07729 - ko00000,ko03000 Transcriptional
KPMDMHFH_00054 4.31e-197 yitS - - S - - - DegV family
KPMDMHFH_00055 2e-120 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
KPMDMHFH_00056 1.44e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPMDMHFH_00058 1.22e-89 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KPMDMHFH_00059 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KPMDMHFH_00061 6.37e-144 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
KPMDMHFH_00062 6.85e-179 - - - S - - - SseB protein N-terminal domain
KPMDMHFH_00063 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KPMDMHFH_00064 1.41e-287 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KPMDMHFH_00065 1.2e-289 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KPMDMHFH_00066 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
KPMDMHFH_00067 5.72e-99 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
KPMDMHFH_00068 3.41e-107 - - - S - - - Putative small multi-drug export protein
KPMDMHFH_00069 1.23e-233 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KPMDMHFH_00070 2.48e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KPMDMHFH_00071 4.96e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 alkyl hydroperoxide reductase
KPMDMHFH_00072 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 alkyl hydroperoxide reductase
KPMDMHFH_00074 2.58e-121 XK27_03570 - - S ko:K19784 - ko00000 reductase
KPMDMHFH_00075 1.89e-95 - - - K - - - Transcriptional regulator, marr family
KPMDMHFH_00076 1.4e-48 XK27_02060 - - S - - - Transglycosylase associated protein
KPMDMHFH_00077 1.02e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
KPMDMHFH_00078 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPMDMHFH_00085 2.14e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KPMDMHFH_00086 1.81e-45 - - - - - - - -
KPMDMHFH_00087 4.88e-218 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
KPMDMHFH_00088 2.7e-257 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KPMDMHFH_00089 3.48e-103 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KPMDMHFH_00090 9.17e-303 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KPMDMHFH_00092 7.19e-197 - - - S - - - CHAP domain
KPMDMHFH_00093 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KPMDMHFH_00094 1.14e-130 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KPMDMHFH_00095 1.85e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KPMDMHFH_00096 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KPMDMHFH_00097 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPMDMHFH_00098 5.24e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KPMDMHFH_00099 1.89e-40 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPMDMHFH_00100 1.45e-235 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KPMDMHFH_00101 6.58e-180 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KPMDMHFH_00102 1.28e-276 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KPMDMHFH_00103 1.36e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPMDMHFH_00104 9.51e-143 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
KPMDMHFH_00105 2.05e-110 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
KPMDMHFH_00106 7.94e-156 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KPMDMHFH_00120 0.0 fliF 2.1.1.72 - N ko:K02409,ko:K02410,ko:K03427 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko01000,ko02035,ko02044,ko02048 bacterial-type flagellum-dependent cell motility
KPMDMHFH_00127 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
KPMDMHFH_00128 0.0 - - - M - - - domain protein
KPMDMHFH_00131 6.64e-11 - - - - - - - -
KPMDMHFH_00132 3.09e-235 XK27_10075 - - S - - - abc transporter atp-binding protein
KPMDMHFH_00133 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00134 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00135 0.0 - - - M ko:K08643 - ko00000,ko01000,ko01002 signal peptide protein, YSIRK family
KPMDMHFH_00136 0.0 - - - GM - - - domain, Protein
KPMDMHFH_00137 1.44e-274 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KPMDMHFH_00138 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
KPMDMHFH_00139 2.5e-39 - - - - - - - -
KPMDMHFH_00140 6.85e-97 - - - - - - - -
KPMDMHFH_00141 2.25e-66 - - - - - - - -
KPMDMHFH_00142 0.0 - - - M - - - family 8
KPMDMHFH_00143 1.04e-270 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the accessory SecA2 SecY2 system specifically required for export of
KPMDMHFH_00144 0.0 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
KPMDMHFH_00145 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system protein Asp2
KPMDMHFH_00146 8.2e-102 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec system protein Asp3
KPMDMHFH_00147 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KPMDMHFH_00148 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KPMDMHFH_00149 2.29e-309 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KPMDMHFH_00150 3.27e-24 - - - S - - - Accessory secretory protein Sec Asp4
KPMDMHFH_00151 3.67e-23 - - - S - - - Accessory secretory protein Sec, Asp5
KPMDMHFH_00152 5.1e-240 - - - M - - - transferase activity, transferring glycosyl groups
KPMDMHFH_00153 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KPMDMHFH_00154 5.43e-90 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KPMDMHFH_00155 1.49e-72 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
KPMDMHFH_00156 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KPMDMHFH_00157 1.07e-103 - - - S - - - Protein of unknown function (DUF3021)
KPMDMHFH_00158 3.78e-92 - - - K - - - LytTr DNA-binding domain
KPMDMHFH_00160 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KPMDMHFH_00162 1.03e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KPMDMHFH_00163 1.5e-135 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
KPMDMHFH_00164 8.98e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KPMDMHFH_00165 5.07e-261 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KPMDMHFH_00166 8.92e-87 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
KPMDMHFH_00167 7.89e-167 - - - S - - - CAAX protease self-immunity
KPMDMHFH_00168 6.43e-301 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
KPMDMHFH_00169 3.59e-88 - - - K - - - Transcriptional regulator, MarR family
KPMDMHFH_00170 6.98e-127 maa 2.3.1.79 - GK ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
KPMDMHFH_00171 2.21e-176 - - - S - - - N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
KPMDMHFH_00172 0.0 - 3.5.1.28 - M ko:K01448,ko:K13733,ko:K20276 ko01503,ko02024,ko05100,map01503,map02024,map05100 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 domain protein
KPMDMHFH_00173 1.86e-34 - - - L - - - Transposase (IS116 IS110 IS902 family)
KPMDMHFH_00174 1.13e-206 - - - L - - - Transposase
KPMDMHFH_00175 3.61e-165 bipA - - S - - - protein secretion
KPMDMHFH_00182 1.92e-212 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
KPMDMHFH_00183 4.12e-137 - - - S - - - Domain of unknown function (DUF1803)
KPMDMHFH_00184 1.99e-132 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KPMDMHFH_00185 1.27e-175 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
KPMDMHFH_00186 5.34e-314 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPMDMHFH_00187 4.39e-244 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
KPMDMHFH_00188 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KPMDMHFH_00189 1.4e-147 yhfA - - S - - - HAD hydrolase, family IA, variant 3
KPMDMHFH_00190 2.27e-179 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
KPMDMHFH_00191 2.67e-96 XK27_02735 - - K - - - Transcriptional regulator, MarR family
KPMDMHFH_00192 8.56e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPMDMHFH_00193 2.12e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPMDMHFH_00194 1.08e-219 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
KPMDMHFH_00195 4.33e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
KPMDMHFH_00196 5.57e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
KPMDMHFH_00197 3.03e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KPMDMHFH_00198 1e-82 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KPMDMHFH_00199 1.19e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KPMDMHFH_00200 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KPMDMHFH_00201 6.95e-204 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KPMDMHFH_00202 4.63e-177 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KPMDMHFH_00203 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KPMDMHFH_00204 2.22e-290 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KPMDMHFH_00205 9.22e-164 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
KPMDMHFH_00206 1.12e-212 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KPMDMHFH_00207 0.0 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KPMDMHFH_00208 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPMDMHFH_00209 4.25e-289 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KPMDMHFH_00210 5.41e-06 - - - - - - - -
KPMDMHFH_00211 3.2e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KPMDMHFH_00212 1.85e-284 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPMDMHFH_00213 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KPMDMHFH_00214 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KPMDMHFH_00215 9.37e-118 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
KPMDMHFH_00216 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KPMDMHFH_00217 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KPMDMHFH_00218 1.99e-170 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPMDMHFH_00219 2.63e-82 WQ51_03320 - - S - - - cog cog4835
KPMDMHFH_00220 1.88e-188 - - - S - - - EDD domain protein, DegV family
KPMDMHFH_00221 2.21e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KPMDMHFH_00222 5.22e-276 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KPMDMHFH_00223 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00224 1.56e-30 - - - S - - - Short repeat of unknown function (DUF308)
KPMDMHFH_00225 4.05e-165 - - - F - - - AdP-ribose pyrophosphatase
KPMDMHFH_00226 1.26e-269 nadR - - H - - - adenylyltransferase
KPMDMHFH_00227 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KPMDMHFH_00228 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
KPMDMHFH_00229 2.73e-92 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KPMDMHFH_00230 2.64e-93 - - - K - - - DNA-binding transcription factor activity
KPMDMHFH_00231 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00232 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00233 3.17e-144 - - - K - - - Acetyltransferase (GNAT) family
KPMDMHFH_00234 2.07e-142 - 2.7.6.5 - S ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
KPMDMHFH_00235 8.64e-153 dltr - - T - - - response regulator
KPMDMHFH_00236 1.34e-277 sptS - - T - - - Histidine kinase
KPMDMHFH_00237 2.78e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KPMDMHFH_00238 7.89e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KPMDMHFH_00239 2e-206 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
KPMDMHFH_00240 2.72e-46 yozE - - S - - - Belongs to the UPF0346 family
KPMDMHFH_00241 6.88e-208 sip - - M - - - LysM domain protein
KPMDMHFH_00242 1.11e-240 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
KPMDMHFH_00246 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPMDMHFH_00247 1.92e-202 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
KPMDMHFH_00248 3.03e-215 - - - K - - - transcriptional regulator (lysR family)
KPMDMHFH_00249 6.05e-136 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
KPMDMHFH_00250 0.0 - - - S - - - Glucan-binding protein C
KPMDMHFH_00251 3.51e-224 coiA - - S ko:K06198 - ko00000 Competence protein
KPMDMHFH_00252 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KPMDMHFH_00253 1.43e-275 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
KPMDMHFH_00254 5.91e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
KPMDMHFH_00255 1.78e-234 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
KPMDMHFH_00256 9.32e-112 XK27_03390 - - S - - - LURP-one-related
KPMDMHFH_00257 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPMDMHFH_00258 0.0 - - - M - - - GBS Bsp-like repeat
KPMDMHFH_00259 4.83e-176 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
KPMDMHFH_00261 1.14e-171 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
KPMDMHFH_00262 2.19e-290 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KPMDMHFH_00263 9.73e-18 - - - - - - - -
KPMDMHFH_00264 0.0 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
KPMDMHFH_00265 1.68e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KPMDMHFH_00266 4.37e-285 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
KPMDMHFH_00267 8.08e-236 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KPMDMHFH_00268 3.86e-281 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KPMDMHFH_00269 1.04e-163 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KPMDMHFH_00270 5.23e-257 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
KPMDMHFH_00271 5.16e-192 icaB - - G - - - deacetylase
KPMDMHFH_00272 8.5e-303 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KPMDMHFH_00273 3.54e-196 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KPMDMHFH_00274 5.69e-189 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
KPMDMHFH_00276 1.38e-17 coiA - - S ko:K06198 - ko00000 Competence protein
KPMDMHFH_00279 7.24e-134 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KPMDMHFH_00280 1.43e-127 - - - J - - - Acetyltransferase (GNAT) domain
KPMDMHFH_00281 9.55e-127 - - - F - - - Shikimate kinase
KPMDMHFH_00282 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KPMDMHFH_00283 5.46e-313 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
KPMDMHFH_00284 0.0 - - - T - - - Histidine kinase
KPMDMHFH_00286 6.54e-109 - - - L - - - HNH nucleases
KPMDMHFH_00287 5.88e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPMDMHFH_00288 1.66e-155 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KPMDMHFH_00289 2.96e-85 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KPMDMHFH_00290 4.99e-113 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPMDMHFH_00291 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPMDMHFH_00292 9.08e-202 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPMDMHFH_00293 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPMDMHFH_00294 1.24e-89 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KPMDMHFH_00295 1.44e-277 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KPMDMHFH_00296 6.46e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPMDMHFH_00297 3.13e-173 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KPMDMHFH_00298 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KPMDMHFH_00300 9.41e-140 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPMDMHFH_00301 3.06e-204 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
KPMDMHFH_00302 1.36e-175 yaaT - - S - - - stage 0 sporulation protein
KPMDMHFH_00303 2e-73 yabA - - L - - - Involved in initiation control of chromosome replication
KPMDMHFH_00304 4.69e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KPMDMHFH_00305 2.03e-290 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
KPMDMHFH_00306 1.86e-70 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
KPMDMHFH_00307 3.77e-139 mur1 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
KPMDMHFH_00308 4.95e-186 XK27_04800 - - S - - - Sucrose-6F-phosphate phosphohydrolase
KPMDMHFH_00309 1.61e-97 - - - S - - - Bacterial inner membrane protein
KPMDMHFH_00310 6.31e-149 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
KPMDMHFH_00311 0.0 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
KPMDMHFH_00312 2.48e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KPMDMHFH_00313 3.9e-285 - - - S - - - membrane
KPMDMHFH_00314 1.23e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KPMDMHFH_00315 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KPMDMHFH_00316 1.17e-51 ynzC - - S - - - UPF0291 protein
KPMDMHFH_00317 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
KPMDMHFH_00319 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KPMDMHFH_00320 3.03e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPMDMHFH_00324 9.3e-91 - - - K - - - Helix-turn-helix
KPMDMHFH_00325 6.49e-56 - - - - - - - -
KPMDMHFH_00327 6.02e-216 lysR - - K - - - transcriptional regulator (lysR family)
KPMDMHFH_00328 1.63e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KPMDMHFH_00329 2.52e-208 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KPMDMHFH_00330 1.45e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPMDMHFH_00331 2.86e-281 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
KPMDMHFH_00332 2.37e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KPMDMHFH_00333 7.9e-270 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
KPMDMHFH_00334 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
KPMDMHFH_00335 2.33e-161 - - - J - - - Putative SAM-dependent methyltransferase
KPMDMHFH_00336 1.71e-246 - - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KPMDMHFH_00337 4.6e-157 salX - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KPMDMHFH_00338 9.26e-271 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
KPMDMHFH_00339 1.7e-101 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPMDMHFH_00340 6.49e-65 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KPMDMHFH_00345 2.41e-188 - - - - - - - -
KPMDMHFH_00347 2.84e-240 - - - L - - - DNA integration
KPMDMHFH_00348 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_00349 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_00350 4.12e-253 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KPMDMHFH_00351 4.63e-161 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KPMDMHFH_00352 6.51e-249 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
KPMDMHFH_00353 2.18e-147 - - - S - - - VIT family
KPMDMHFH_00354 6.56e-164 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KPMDMHFH_00355 1.55e-272 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KPMDMHFH_00356 2.88e-251 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
KPMDMHFH_00358 2.02e-176 - - - E - - - Alpha beta hydrolase
KPMDMHFH_00359 3.61e-64 ykoJ - - S - - - membrane
KPMDMHFH_00360 1.78e-140 - - - T - - - Response regulator receiver domain protein
KPMDMHFH_00361 1.49e-226 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
KPMDMHFH_00362 8.35e-315 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPMDMHFH_00363 1.81e-133 - - - J ko:K09962 - ko00000 protein conserved in bacteria
KPMDMHFH_00364 1.96e-196 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
KPMDMHFH_00365 2.01e-216 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
KPMDMHFH_00366 4.23e-222 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
KPMDMHFH_00367 7.2e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KPMDMHFH_00368 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
KPMDMHFH_00369 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPMDMHFH_00370 8.64e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
KPMDMHFH_00371 4.4e-43 - - - - - - - -
KPMDMHFH_00372 7.33e-152 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPMDMHFH_00373 0.0 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
KPMDMHFH_00374 6.99e-242 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KPMDMHFH_00375 0.0 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KPMDMHFH_00377 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPMDMHFH_00378 2.94e-207 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KPMDMHFH_00379 7.72e-256 - - - S - - - Protein of unknown function (DUF3114)
KPMDMHFH_00380 1.64e-39 pspC - - KT - - - PspC domain protein
KPMDMHFH_00381 3.52e-152 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
KPMDMHFH_00382 1.08e-102 - - - K - - - hmm pf08876
KPMDMHFH_00383 2.35e-286 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
KPMDMHFH_00384 6.56e-273 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
KPMDMHFH_00385 3.63e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KPMDMHFH_00386 5.77e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPMDMHFH_00387 2.97e-30 - - - - - - - -
KPMDMHFH_00388 1.79e-287 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KPMDMHFH_00389 9.58e-144 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KPMDMHFH_00390 0.0 lysP - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
KPMDMHFH_00391 1.88e-222 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
KPMDMHFH_00392 3.14e-42 - - - S - - - Domain of unknown function (DUF1912)
KPMDMHFH_00393 4.35e-19 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
KPMDMHFH_00394 1.05e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KPMDMHFH_00395 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPMDMHFH_00396 3.54e-189 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 adenylyltransferase
KPMDMHFH_00397 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPMDMHFH_00398 7.12e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KPMDMHFH_00399 4.89e-22 - - - S - - - Protein of unknown function (DUF2969)
KPMDMHFH_00402 2.24e-266 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
KPMDMHFH_00405 1.19e-136 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
KPMDMHFH_00406 2.28e-149 - - - M - - - Pfam SNARE associated Golgi protein
KPMDMHFH_00407 2.37e-289 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
KPMDMHFH_00408 2.99e-221 - - - S - - - oxidoreductase
KPMDMHFH_00409 2.23e-65 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
KPMDMHFH_00410 5.5e-111 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
KPMDMHFH_00411 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
KPMDMHFH_00412 6.14e-233 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KPMDMHFH_00413 3.31e-47 ykuJ - - S - - - protein conserved in bacteria
KPMDMHFH_00414 2.2e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KPMDMHFH_00415 1.05e-167 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00416 6.08e-102 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
KPMDMHFH_00417 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
KPMDMHFH_00418 2.42e-12 - - - - - - - -
KPMDMHFH_00419 7.21e-191 - - - I - - - Alpha/beta hydrolase family
KPMDMHFH_00420 3.16e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPMDMHFH_00421 1.42e-182 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KPMDMHFH_00422 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
KPMDMHFH_00423 2.63e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPMDMHFH_00424 2.05e-194 licT - - K ko:K03488 - ko00000,ko03000 antiterminator
KPMDMHFH_00425 1.31e-113 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KPMDMHFH_00426 2.97e-86 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
KPMDMHFH_00427 3.34e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KPMDMHFH_00428 5.27e-196 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KPMDMHFH_00429 1.35e-133 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPMDMHFH_00430 5.68e-279 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
KPMDMHFH_00431 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
KPMDMHFH_00432 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KPMDMHFH_00433 1.98e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KPMDMHFH_00434 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPMDMHFH_00435 3.35e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
KPMDMHFH_00436 3.62e-247 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
KPMDMHFH_00437 6.39e-234 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
KPMDMHFH_00438 8.37e-257 XK27_07735 - - S - - - YjbR
KPMDMHFH_00439 2.01e-247 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KPMDMHFH_00440 3.31e-98 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
KPMDMHFH_00441 6.13e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KPMDMHFH_00442 1.1e-34 WQ51_00785 - - - - - - -
KPMDMHFH_00443 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
KPMDMHFH_00444 1.19e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
KPMDMHFH_00445 1.37e-149 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KPMDMHFH_00446 1.39e-197 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPMDMHFH_00447 2.8e-255 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KPMDMHFH_00448 1.83e-279 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KPMDMHFH_00449 4.33e-262 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
KPMDMHFH_00450 2.99e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
KPMDMHFH_00451 1.16e-216 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KPMDMHFH_00452 1.77e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KPMDMHFH_00453 6.53e-113 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KPMDMHFH_00454 1.4e-196 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KPMDMHFH_00455 0.0 msrR - - K - - - Transcriptional regulator
KPMDMHFH_00456 4.28e-180 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 C4-dicarboxylate transporter malic acid transport
KPMDMHFH_00457 1.82e-255 - - - I - - - acyl-CoA dehydrogenase
KPMDMHFH_00458 1.82e-126 mip - - S - - - hydroperoxide reductase activity
KPMDMHFH_00459 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPMDMHFH_00460 1.3e-69 - - - K - - - TfoX N-terminal domain
KPMDMHFH_00461 2.41e-25 - - - S ko:K06889 - ko00000 alpha beta
KPMDMHFH_00462 3.16e-83 - - - K - - - Acetyltransferase (GNAT) domain
KPMDMHFH_00463 1.66e-125 - - - - - - - -
KPMDMHFH_00465 2.82e-139 - - - K - - - Transcriptional regulator
KPMDMHFH_00466 2.3e-167 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KPMDMHFH_00467 0.0 - - - S ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
KPMDMHFH_00468 3.67e-45 - - - S - - - Protein of unknown function (DUF1648)
KPMDMHFH_00469 4.57e-71 - - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
KPMDMHFH_00470 2.42e-160 lyrA - - S - - - CAAX amino terminal protease family protein
KPMDMHFH_00472 2.71e-30 - - - L ko:K07483,ko:K07497 - ko00000 PFAM Integrase catalytic region
KPMDMHFH_00473 2.05e-103 - - - S - - - Protein of unknown function (DUF1643)
KPMDMHFH_00474 5.51e-147 - - - - - - - -
KPMDMHFH_00475 2.54e-168 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KPMDMHFH_00476 1.38e-168 - - - S - - - Domain of unknown function (DUF4336)
KPMDMHFH_00477 9.79e-260 yycB - - P ko:K03449 - ko00000,ko02000 transporter
KPMDMHFH_00478 3.39e-191 ChZ00x2 - - S - - - EDD domain protein, DegV family
KPMDMHFH_00479 8.11e-125 - - - K - - - Bacterial regulatory proteins, tetR family
KPMDMHFH_00480 3.48e-128 yagB - - F ko:K06950 - ko00000 HD superfamily hydrolase
KPMDMHFH_00481 2.05e-163 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family
KPMDMHFH_00482 8.04e-142 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
KPMDMHFH_00484 4.94e-19 yjdB - - S - - - Domain of unknown function (DUF4767)
KPMDMHFH_00485 0.0 - - - P - - - Major facilitator superfamily
KPMDMHFH_00486 2.04e-122 tetR - - K - - - transcriptional regulator
KPMDMHFH_00487 5.43e-192 - - - S - - - Domain of unknown function (DUF4300)
KPMDMHFH_00488 3.69e-157 - - - V - - - CAAX protease self-immunity
KPMDMHFH_00489 3.52e-218 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPMDMHFH_00490 7.63e-169 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KPMDMHFH_00491 2.12e-230 fatB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KPMDMHFH_00492 3.33e-153 - - - S - - - Putative esterase
KPMDMHFH_00493 3.67e-197 yegS - - I - - - Diacylglycerol kinase
KPMDMHFH_00494 3.17e-222 - - - S - - - Domain of unknown function (DUF389)
KPMDMHFH_00495 6.34e-33 ytgB - - S - - - Membrane
KPMDMHFH_00496 2.66e-31 - - - S - - - Belongs to the UPF0337 (CsbD) family
KPMDMHFH_00497 4.02e-215 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
KPMDMHFH_00498 4.81e-209 acoA - - C ko:K21416 - ko00000,ko01000 Acetoin dehydrogenase E1 component subunit alpha
KPMDMHFH_00499 2.63e-222 acoB - - C ko:K21417 - ko00000,ko01000 dehydrogenase E1 component
KPMDMHFH_00500 3.08e-179 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KPMDMHFH_00501 1.03e-107 - - - Q - - - Methyltransferase domain
KPMDMHFH_00502 8.31e-101 - - - K - - - TetR family transcriptional regulator
KPMDMHFH_00503 1.61e-64 - - - - - - - -
KPMDMHFH_00504 1.65e-162 - - - V - - - CAAX protease self-immunity
KPMDMHFH_00506 2.89e-28 - - - M - - - Bacterial lipoprotein
KPMDMHFH_00507 3.25e-79 - - - S - - - Protein of unknown function (DUF1722)
KPMDMHFH_00508 6.81e-83 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
KPMDMHFH_00510 3.73e-68 - - - - - - - -
KPMDMHFH_00511 2.25e-119 - - - S - - - CAAX protease self-immunity
KPMDMHFH_00512 1.15e-151 - - - E - - - GDSL-like Lipase/Acylhydrolase
KPMDMHFH_00513 1.39e-134 - - - - - - - -
KPMDMHFH_00514 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 Sulfate permease and related transporters (MFS superfamily)
KPMDMHFH_00515 1.19e-191 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
KPMDMHFH_00516 5.4e-198 XK27_03015 - - S ko:K07089 - ko00000 permease
KPMDMHFH_00518 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
KPMDMHFH_00519 1.17e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KPMDMHFH_00520 8.42e-55 WQ51_05770 - - KT - - - PspC domain
KPMDMHFH_00521 1.12e-215 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KPMDMHFH_00522 2.14e-190 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPMDMHFH_00523 9.98e-28 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KPMDMHFH_00524 6.48e-89 ytxH - - S - - - General stress protein
KPMDMHFH_00526 4.13e-227 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KPMDMHFH_00527 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
KPMDMHFH_00528 4.42e-112 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
KPMDMHFH_00530 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
KPMDMHFH_00531 6.58e-295 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KPMDMHFH_00532 3.6e-19 - - - - - - - -
KPMDMHFH_00533 1.19e-265 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
KPMDMHFH_00534 1.39e-285 - - - L - - - DNA mismatch repair enzyme MutH
KPMDMHFH_00535 2.15e-257 - - - S - - - SIR2-like domain
KPMDMHFH_00536 6.35e-298 - - - S ko:K06915 - ko00000 Domain of unknown function DUF87
KPMDMHFH_00539 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KPMDMHFH_00540 3.43e-205 - - - M - - - LysM domain
KPMDMHFH_00541 1.22e-36 - - - - - - - -
KPMDMHFH_00542 3.26e-224 - - - S ko:K07025 - ko00000 hydrolase
KPMDMHFH_00544 2.41e-148 pgm - - G - - - Phosphoglycerate mutase
KPMDMHFH_00545 8.68e-106 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KPMDMHFH_00546 9.55e-192 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
KPMDMHFH_00547 2.29e-35 - - - P - - - Hemerythrin HHE cation binding domain protein
KPMDMHFH_00548 5.24e-195 hmpP2 - - G - - - hydrolase
KPMDMHFH_00549 2.07e-147 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPMDMHFH_00550 2.99e-270 - - - S - - - Protein of unknown function (DUF2974)
KPMDMHFH_00551 6.03e-170 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KPMDMHFH_00553 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KPMDMHFH_00554 1.73e-121 - - - - ko:K15051 - ko00000 -
KPMDMHFH_00556 0.000151 - - - - - - - -
KPMDMHFH_00557 7.91e-166 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
KPMDMHFH_00558 0.0 - - - S - - - KAP family P-loop domain
KPMDMHFH_00559 4.57e-165 - - - S - - - Protein conserved in bacteria
KPMDMHFH_00560 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KPMDMHFH_00561 1.97e-179 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
KPMDMHFH_00562 0.0 - - - M - - - Right handed beta helix region
KPMDMHFH_00563 7.21e-238 spd - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
KPMDMHFH_00564 8.87e-120 lemA - - S ko:K03744 - ko00000 LemA family
KPMDMHFH_00565 5.96e-190 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KPMDMHFH_00566 4.88e-154 sirR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
KPMDMHFH_00567 1.32e-218 psaA - - P ko:K11704,ko:K19971,ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KPMDMHFH_00568 5.83e-171 mtsC - - P ko:K11705,ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type Mn2 Zn2 transport systems, permease components
KPMDMHFH_00569 3.93e-162 sitB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPMDMHFH_00570 9.93e-93 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
KPMDMHFH_00571 5.6e-85 - - - S - - - Domain of unknown function (DUF4430)
KPMDMHFH_00572 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KPMDMHFH_00573 3.16e-235 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KPMDMHFH_00574 1.59e-143 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
KPMDMHFH_00575 4.09e-211 - - - V - - - D-alanyl-D-alanine carboxypeptidase
KPMDMHFH_00576 2.33e-133 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
KPMDMHFH_00577 1.06e-116 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KPMDMHFH_00578 9.48e-102 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
KPMDMHFH_00579 1.79e-35 yqgQ - - S - - - protein conserved in bacteria
KPMDMHFH_00580 1.14e-226 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
KPMDMHFH_00581 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KPMDMHFH_00582 4.51e-13 - - - S - - - Protein of unknown function (DUF3165)
KPMDMHFH_00583 1.76e-313 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KPMDMHFH_00584 2.49e-254 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KPMDMHFH_00585 1.72e-184 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KPMDMHFH_00586 4.95e-292 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KPMDMHFH_00587 3.44e-299 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KPMDMHFH_00588 1.62e-158 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KPMDMHFH_00589 2.34e-128 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
KPMDMHFH_00590 1.13e-40 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
KPMDMHFH_00591 2.12e-183 ylmH - - S - - - conserved protein, contains S4-like domain
KPMDMHFH_00592 2.89e-193 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
KPMDMHFH_00593 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KPMDMHFH_00594 4.51e-236 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPMDMHFH_00595 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPMDMHFH_00596 9.66e-46 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
KPMDMHFH_00597 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KPMDMHFH_00598 3.35e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
KPMDMHFH_00599 1.46e-282 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
KPMDMHFH_00600 2.72e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
KPMDMHFH_00601 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KPMDMHFH_00602 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KPMDMHFH_00603 6.48e-207 XK27_05670 - - S ko:K07017 - ko00000 Putative esterase
KPMDMHFH_00604 1.85e-196 XK27_05675 - - S - - - Esterase
KPMDMHFH_00605 8.51e-289 XK27_05680 - - M - - - carbamoylphosphate synthase large subunit
KPMDMHFH_00606 5.06e-240 yfmL - - L - - - DEAD DEAH box helicase
KPMDMHFH_00607 5.27e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KPMDMHFH_00608 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
KPMDMHFH_00609 7.55e-53 - - - S - - - yiaA/B two helix domain
KPMDMHFH_00610 2.22e-171 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
KPMDMHFH_00611 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KPMDMHFH_00612 2.07e-192 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
KPMDMHFH_00613 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
KPMDMHFH_00614 7.91e-190 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KPMDMHFH_00615 4.31e-210 ybbR - - S - - - Protein conserved in bacteria
KPMDMHFH_00616 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPMDMHFH_00617 5.03e-84 mesH - - S - - - GtrA-like protein
KPMDMHFH_00618 5.86e-157 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KPMDMHFH_00619 6.85e-182 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KPMDMHFH_00620 2.97e-183 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
KPMDMHFH_00621 3.97e-254 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
KPMDMHFH_00622 0.0 - - - S - - - phospholipase Carboxylesterase
KPMDMHFH_00623 7.83e-206 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KPMDMHFH_00624 2.26e-141 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KPMDMHFH_00625 1.11e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KPMDMHFH_00628 8.98e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KPMDMHFH_00629 2.51e-181 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
KPMDMHFH_00630 7.1e-177 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KPMDMHFH_00631 1.84e-153 - - - S - - - tigr01906
KPMDMHFH_00632 3.69e-178 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
KPMDMHFH_00633 5.59e-199 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
KPMDMHFH_00634 1.28e-80 XK27_08085 - - - - - - -
KPMDMHFH_00635 1.08e-245 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KPMDMHFH_00636 1.14e-228 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KPMDMHFH_00637 2.93e-151 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KPMDMHFH_00638 4.35e-300 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KPMDMHFH_00639 6.76e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
KPMDMHFH_00640 8.15e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KPMDMHFH_00641 2.9e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KPMDMHFH_00642 4.63e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KPMDMHFH_00643 3.36e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KPMDMHFH_00644 5.16e-66 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 - E ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
KPMDMHFH_00646 0.0 - - - S - - - dextransucrase activity
KPMDMHFH_00647 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
KPMDMHFH_00650 3.93e-184 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KPMDMHFH_00651 4.28e-177 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00652 1.46e-282 - - - L - - - transposase IS116 IS110 IS902 family
KPMDMHFH_00653 4.31e-98 - - - L - - - Transposase
KPMDMHFH_00654 4.49e-175 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
KPMDMHFH_00655 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
KPMDMHFH_00657 0.0 - - - S - - - Protein of unknown function (DUF3114)
KPMDMHFH_00658 2.67e-130 - - - K - - - Acetyltransferase GNAT Family
KPMDMHFH_00659 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KPMDMHFH_00660 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
KPMDMHFH_00661 1.33e-228 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 glucose-1-phosphate adenylyltransferase
KPMDMHFH_00662 7.3e-250 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KPMDMHFH_00663 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KPMDMHFH_00664 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
KPMDMHFH_00665 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KPMDMHFH_00666 7.82e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KPMDMHFH_00667 1.98e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KPMDMHFH_00668 9.14e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KPMDMHFH_00671 2.7e-146 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPMDMHFH_00672 2.42e-219 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KPMDMHFH_00673 2.86e-150 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Membrane
KPMDMHFH_00674 1.4e-140 - - - P ko:K10716 - ko00000,ko02000 Ion transport protein
KPMDMHFH_00675 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KPMDMHFH_00676 2.2e-174 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KPMDMHFH_00677 2.59e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KPMDMHFH_00678 6.76e-218 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPMDMHFH_00679 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPMDMHFH_00680 2.28e-60 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
KPMDMHFH_00681 4.34e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KPMDMHFH_00682 1.76e-277 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KPMDMHFH_00683 1.01e-188 XK27_02985 - - S - - - overlaps another CDS with the same product name
KPMDMHFH_00684 6.37e-188 - - - S - - - overlaps another CDS with the same product name
KPMDMHFH_00685 8.13e-82 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
KPMDMHFH_00686 5.01e-160 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_00687 1.83e-165 - - - V - - - Psort location CytoplasmicMembrane, score
KPMDMHFH_00688 1.17e-217 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KPMDMHFH_00689 6.62e-257 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KPMDMHFH_00690 3.18e-210 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_00691 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_00692 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KPMDMHFH_00693 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KPMDMHFH_00694 3.38e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
KPMDMHFH_00695 1.05e-219 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KPMDMHFH_00696 5.67e-196 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KPMDMHFH_00697 3.55e-155 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
KPMDMHFH_00698 3.35e-131 yjbK - - S - - - Adenylate cyclase
KPMDMHFH_00699 9.66e-224 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPMDMHFH_00700 1.45e-260 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
KPMDMHFH_00701 8.79e-79 XK27_04120 - - S - - - Putative amino acid metabolism
KPMDMHFH_00702 1.83e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KPMDMHFH_00703 5.47e-168 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
KPMDMHFH_00704 4.43e-152 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
KPMDMHFH_00705 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
KPMDMHFH_00706 2.26e-286 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KPMDMHFH_00707 2.19e-181 - - - GM ko:K01992,ko:K09690,ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
KPMDMHFH_00708 1.05e-226 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
KPMDMHFH_00709 7.51e-285 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
KPMDMHFH_00710 1.03e-285 - - GT4 M ko:K00754 - ko00000,ko01000 transferase activity, transferring glycosyl groups
KPMDMHFH_00711 4.5e-277 - - - M - - - Psort location CytoplasmicMembrane, score
KPMDMHFH_00712 0.0 - - - M - - - Glycosyltransferase like family 2
KPMDMHFH_00713 1.89e-181 - - - S - - - Glycosyltransferase like family 2
KPMDMHFH_00714 6.77e-154 - - - S - - - Glycosyltransferase like family 2
KPMDMHFH_00715 4.72e-242 - - - S - - - membrane protein involved in the export of O-antigen and teichoic acid
KPMDMHFH_00716 1.31e-135 - - - S - - - Glycosyltransferase group 2 family protein
KPMDMHFH_00717 2.21e-63 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
KPMDMHFH_00718 1.39e-160 - - - S - - - Glycosyl transferase family 2
KPMDMHFH_00719 4.72e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KPMDMHFH_00720 3.07e-272 - - - S - - - Predicted membrane protein (DUF2142)
KPMDMHFH_00721 3.62e-216 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
KPMDMHFH_00722 4.86e-74 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
KPMDMHFH_00723 2.49e-256 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KPMDMHFH_00724 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KPMDMHFH_00725 2.93e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KPMDMHFH_00726 8.61e-28 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KPMDMHFH_00727 4.55e-172 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KPMDMHFH_00728 7.57e-267 arcT - - E - - - Aminotransferase
KPMDMHFH_00729 5.38e-178 - - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KPMDMHFH_00730 1.27e-181 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
KPMDMHFH_00731 3.57e-108 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
KPMDMHFH_00732 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KPMDMHFH_00734 2.83e-210 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
KPMDMHFH_00735 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
KPMDMHFH_00736 3.54e-176 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00737 5.23e-25 XK27_00735 - - - - - - -
KPMDMHFH_00738 3.8e-315 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KPMDMHFH_00739 9.86e-10 - - - S - - - Protein of unknown function (DUF4044)
KPMDMHFH_00740 1.68e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KPMDMHFH_00741 4.89e-09 - - - O - - - ADP-ribosylglycohydrolase
KPMDMHFH_00742 1.99e-82 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
KPMDMHFH_00743 4.09e-80 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
KPMDMHFH_00745 6.29e-195 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
KPMDMHFH_00747 4.64e-143 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
KPMDMHFH_00748 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KPMDMHFH_00749 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPMDMHFH_00750 5.1e-127 - - - S - - - IA, variant 1
KPMDMHFH_00751 6.23e-149 lrgB - - M - - - Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KPMDMHFH_00752 2.4e-73 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
KPMDMHFH_00754 4.86e-77 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KPMDMHFH_00755 7.39e-90 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
KPMDMHFH_00756 6.14e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPMDMHFH_00757 1.62e-135 - - - M - - - Acetyltransferase (GNAT) domain
KPMDMHFH_00758 1.47e-266 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KPMDMHFH_00759 3.69e-204 - - - GK - - - ROK family
KPMDMHFH_00760 2.36e-93 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
KPMDMHFH_00761 4.79e-196 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
KPMDMHFH_00762 7.79e-262 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
KPMDMHFH_00763 3.07e-167 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
KPMDMHFH_00764 4.03e-179 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
KPMDMHFH_00765 9.28e-271 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KPMDMHFH_00766 3.77e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
KPMDMHFH_00767 3.96e-107 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KPMDMHFH_00768 1.44e-79 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KPMDMHFH_00769 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KPMDMHFH_00770 1.06e-187 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KPMDMHFH_00771 4.02e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
KPMDMHFH_00772 0.0 ydaO - - E - - - amino acid
KPMDMHFH_00773 1.77e-300 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KPMDMHFH_00774 3.71e-49 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
KPMDMHFH_00775 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KPMDMHFH_00776 0.000133 yebC - - M - - - Membrane
KPMDMHFH_00777 4.23e-258 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KPMDMHFH_00778 1.65e-160 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
KPMDMHFH_00779 1.11e-233 - - - O - - - protein import
KPMDMHFH_00780 1.66e-213 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
KPMDMHFH_00781 6.9e-15 yjdB - - S - - - Domain of unknown function (DUF4767)
KPMDMHFH_00782 3.53e-255 XK27_00915 - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPMDMHFH_00784 5.11e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KPMDMHFH_00785 6.75e-95 - - - S - - - QueT transporter
KPMDMHFH_00787 1.18e-227 yfjR - - K - - - regulation of single-species biofilm formation
KPMDMHFH_00789 1.19e-231 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KPMDMHFH_00790 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPMDMHFH_00791 1.71e-111 ccl - - S - - - cog cog4708
KPMDMHFH_00792 1.64e-210 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
KPMDMHFH_00793 4.94e-212 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KPMDMHFH_00794 7.45e-296 ytoI - - K - - - transcriptional regulator containing CBS domains
KPMDMHFH_00795 1.97e-125 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
KPMDMHFH_00796 2.03e-290 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPMDMHFH_00797 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KPMDMHFH_00798 1.79e-132 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
KPMDMHFH_00799 2.5e-183 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
KPMDMHFH_00800 3.17e-203 nodB3 - - G - - - deacetylase
KPMDMHFH_00801 1.75e-180 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
KPMDMHFH_00802 6.85e-55 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
KPMDMHFH_00803 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KPMDMHFH_00804 1.1e-202 corA - - P - - - CorA-like protein
KPMDMHFH_00805 1.51e-82 yjqA - - S - - - Bacterial PH domain
KPMDMHFH_00806 5.34e-128 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
KPMDMHFH_00807 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KPMDMHFH_00808 5.85e-149 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
KPMDMHFH_00809 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KPMDMHFH_00813 1.1e-198 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KPMDMHFH_00814 1.09e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00815 4.6e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_00816 2.46e-148 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_00817 1.08e-244 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KPMDMHFH_00818 1.58e-41 copZ - - P - - - Heavy metal-associated domain protein
KPMDMHFH_00819 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KPMDMHFH_00820 4.11e-95 copY - - K - - - negative regulation of transcription, DNA-templated
KPMDMHFH_00821 5.59e-223 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
KPMDMHFH_00823 3.54e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KPMDMHFH_00824 4.77e-289 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KPMDMHFH_00825 3.76e-129 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
KPMDMHFH_00826 7.94e-173 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
KPMDMHFH_00827 3.01e-228 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KPMDMHFH_00828 7.09e-136 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
KPMDMHFH_00829 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KPMDMHFH_00830 5.98e-55 - 4.2.99.21 - E ko:K04782 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Chorismate mutase type II
KPMDMHFH_00831 2.28e-77 - - - - - - - -
KPMDMHFH_00832 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KPMDMHFH_00833 5.06e-61 - - - - - - - -
KPMDMHFH_00834 2.24e-57 - - - - - - - -
KPMDMHFH_00835 9.82e-65 - - - - - - - -
KPMDMHFH_00836 7.54e-59 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KPMDMHFH_00838 2.75e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_00839 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_00840 3.45e-159 - - - K - - - transcriptional regulator, MerR family
KPMDMHFH_00841 5.11e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KPMDMHFH_00842 5.18e-76 WQ51_02910 - - S - - - Protein of unknown function, DUF536
KPMDMHFH_00843 2.86e-85 XK27_02560 - - S - - - cog cog2151
KPMDMHFH_00844 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
KPMDMHFH_00845 8.1e-281 ytfP - - S ko:K07007 - ko00000 Flavoprotein
KPMDMHFH_00847 8.79e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KPMDMHFH_00848 2.95e-197 ytmP - - M - - - Phosphotransferase
KPMDMHFH_00849 2.35e-220 XK27_05910 - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
KPMDMHFH_00850 1.18e-168 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_00851 3.05e-95 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KPMDMHFH_00855 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
KPMDMHFH_00856 3.77e-248 ylbM - - S - - - Belongs to the UPF0348 family
KPMDMHFH_00857 6.13e-177 XK27_06665 - - Q - - - Methyltransferase domain protein
KPMDMHFH_00858 3.42e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KPMDMHFH_00859 2.64e-135 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
KPMDMHFH_00860 1.3e-151 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPMDMHFH_00861 2.65e-64 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
KPMDMHFH_00862 1.32e-273 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KPMDMHFH_00863 4.52e-128 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
KPMDMHFH_00864 9.25e-197 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KPMDMHFH_00865 6.91e-84 - - - - - - - -
KPMDMHFH_00866 4.98e-280 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPMDMHFH_00867 2.78e-73 - - - - - - - -
KPMDMHFH_00868 4.76e-53 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system cellobiose-specific component IIA
KPMDMHFH_00869 0.0 celR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
KPMDMHFH_00870 4.78e-62 celB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KPMDMHFH_00871 0.0 celA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPMDMHFH_00873 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPMDMHFH_00874 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KPMDMHFH_00875 1.24e-62 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPMDMHFH_00876 5.26e-294 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KPMDMHFH_00877 3.3e-238 - - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KPMDMHFH_00878 2.81e-201 - - - H - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
KPMDMHFH_00879 2.59e-277 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
KPMDMHFH_00880 0.0 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPMDMHFH_00881 6.09e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
KPMDMHFH_00882 2.12e-180 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KPMDMHFH_00883 4.15e-300 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KPMDMHFH_00884 1.25e-97 XK27_03180 - - T - - - universal stress protein
KPMDMHFH_00886 4.91e-202 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPMDMHFH_00888 7.04e-305 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
KPMDMHFH_00889 1.44e-182 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00891 8.13e-34 - - - - - - - -
KPMDMHFH_00892 0.0 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
KPMDMHFH_00894 1.38e-121 mraW1 - - J - - - (SAM)-dependent
KPMDMHFH_00895 7.2e-235 ytqA - - S ko:K07139 - ko00000 radical SAM protein
KPMDMHFH_00896 2.15e-240 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KPMDMHFH_00897 1.87e-113 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KPMDMHFH_00898 1.27e-118 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
KPMDMHFH_00899 1.13e-218 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KPMDMHFH_00900 1.48e-13 - - - S - - - Protein of unknown function (DUF4059)
KPMDMHFH_00901 1.08e-166 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_00902 1.22e-192 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_00904 3.3e-196 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KPMDMHFH_00906 3.58e-260 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPMDMHFH_00907 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
KPMDMHFH_00908 3.03e-184 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
KPMDMHFH_00909 1.23e-95 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPMDMHFH_00911 5.35e-219 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
KPMDMHFH_00912 1.13e-180 cppA - - E - - - CppA N-terminal
KPMDMHFH_00913 2.39e-119 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
KPMDMHFH_00914 4.34e-202 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KPMDMHFH_00915 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KPMDMHFH_00921 9.86e-17 - - - S - - - Bacteriocin class II with double-glycine leader peptide
KPMDMHFH_00922 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_00923 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_00926 3.55e-116 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
KPMDMHFH_00927 7.84e-286 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KPMDMHFH_00928 4.36e-113 yutD - - J - - - protein conserved in bacteria
KPMDMHFH_00929 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KPMDMHFH_00931 3.25e-301 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KPMDMHFH_00932 8.08e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPMDMHFH_00933 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
KPMDMHFH_00934 5.32e-60 ftsL - - D - - - cell division protein FtsL
KPMDMHFH_00935 1.09e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KPMDMHFH_00936 1.1e-136 - - - - - - - -
KPMDMHFH_00938 4.42e-52 - - - J - - - Protein of unknown function (DUF805)
KPMDMHFH_00939 3.36e-76 - - - J - - - Protein of unknown function (DUF805)
KPMDMHFH_00940 2.48e-113 - - - L - - - Endonuclease
KPMDMHFH_00941 1.95e-20 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
KPMDMHFH_00942 7.64e-19 - - - S - - - Protein of unknown function (DUF805)
KPMDMHFH_00943 1.37e-71 - - - S - - - Protein of unknown function (DUF805)
KPMDMHFH_00944 3.21e-285 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KPMDMHFH_00945 9.25e-178 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPMDMHFH_00946 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
KPMDMHFH_00947 2.59e-172 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_00948 1.48e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
KPMDMHFH_00949 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KPMDMHFH_00950 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KPMDMHFH_00951 1.21e-303 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KPMDMHFH_00952 1.7e-297 dcuS 2.7.13.3 - T ko:K02476,ko:K07701,ko:K07706,ko:K11614 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KPMDMHFH_00953 1.5e-14 - - - - - - - -
KPMDMHFH_00956 8.38e-187 - - - V ko:K21397 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
KPMDMHFH_00958 0.0 - - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 MreB/Mbl protein
KPMDMHFH_00959 3.11e-247 mccF - - V - - - LD-carboxypeptidase
KPMDMHFH_00960 1.06e-57 - - - S - - - Sugar efflux transporter for intercellular exchange
KPMDMHFH_00961 4.86e-98 mccF - - V - - - LD-carboxypeptidase
KPMDMHFH_00962 9.64e-153 - - - S - - - membrane
KPMDMHFH_00963 6.23e-97 - - - K - - - LytTr DNA-binding domain
KPMDMHFH_00964 0.0 - - - KT - - - response to antibiotic
KPMDMHFH_00965 1.91e-159 yebC - - M - - - Membrane
KPMDMHFH_00966 0.0 - - - S - - - hydrolases of the HAD superfamily
KPMDMHFH_00967 8.56e-217 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KPMDMHFH_00969 4.07e-43 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
KPMDMHFH_00973 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KPMDMHFH_00974 1.57e-258 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPMDMHFH_00975 4.94e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KPMDMHFH_00976 2.59e-249 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KPMDMHFH_00977 8.28e-251 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KPMDMHFH_00978 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KPMDMHFH_00980 1.2e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KPMDMHFH_00981 1.13e-218 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
KPMDMHFH_00982 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KPMDMHFH_00983 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KPMDMHFH_00984 1.01e-224 scrR - - K ko:K03484 - ko00000,ko03000 Transcriptional regulator
KPMDMHFH_00985 1.09e-95 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPMDMHFH_00986 7.41e-80 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
KPMDMHFH_00987 1.22e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPMDMHFH_00988 3.59e-111 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
KPMDMHFH_00989 4.83e-255 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
KPMDMHFH_00991 3.93e-182 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
KPMDMHFH_00992 2.67e-39 blpT - - - - - - -
KPMDMHFH_00996 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KPMDMHFH_00997 2.01e-216 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
KPMDMHFH_00998 1.98e-157 XK27_01040 - - S - - - Protein of unknown function (DUF1129)
KPMDMHFH_01000 4.1e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KPMDMHFH_01001 4.18e-118 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KPMDMHFH_01002 6.54e-63 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KPMDMHFH_01003 1.6e-52 XK27_05745 - - - - - - -
KPMDMHFH_01004 3.17e-282 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
KPMDMHFH_01006 8.53e-34 - - - - - - - -
KPMDMHFH_01008 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPMDMHFH_01009 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KPMDMHFH_01010 4.82e-121 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
KPMDMHFH_01011 1.18e-20 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KPMDMHFH_01012 1.7e-195 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPMDMHFH_01013 6.4e-149 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KPMDMHFH_01014 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KPMDMHFH_01015 6.6e-62 - - - S - - - branched-chain amino acid
KPMDMHFH_01016 9.85e-146 XK27_12120 - - E - - - AzlC protein
KPMDMHFH_01017 7.47e-235 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KPMDMHFH_01018 1.21e-93 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KPMDMHFH_01019 3.49e-148 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
KPMDMHFH_01020 1.3e-44 ykzG - - S - - - Belongs to the UPF0356 family
KPMDMHFH_01021 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPMDMHFH_01022 4.88e-147 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
KPMDMHFH_01023 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KPMDMHFH_01024 4e-82 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
KPMDMHFH_01025 1.79e-112 - - - S - - - Fusaric acid resistance protein-like
KPMDMHFH_01026 3.32e-283 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KPMDMHFH_01027 2.38e-159 - - - - - - - -
KPMDMHFH_01028 4.47e-231 gap 1.2.1.12 - C ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
KPMDMHFH_01029 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KPMDMHFH_01030 4.66e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KPMDMHFH_01031 4.89e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KPMDMHFH_01032 7.91e-184 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
KPMDMHFH_01033 4.14e-229 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
KPMDMHFH_01034 2.42e-231 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
KPMDMHFH_01035 2.16e-150 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KPMDMHFH_01036 1.15e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KPMDMHFH_01037 2.53e-207 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KPMDMHFH_01039 1.76e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KPMDMHFH_01040 1.81e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPMDMHFH_01041 3.2e-183 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
KPMDMHFH_01042 8.64e-97 yneT - - S ko:K06929 - ko00000 CoA-binding protein
KPMDMHFH_01043 3.11e-67 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KPMDMHFH_01044 3.16e-184 - - - S - - - Macro domain protein
KPMDMHFH_01045 8.55e-51 isplu5A - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
KPMDMHFH_01046 4.67e-80 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
KPMDMHFH_01047 4.62e-70 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis
KPMDMHFH_01049 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KPMDMHFH_01050 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
KPMDMHFH_01051 8.71e-63 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-quinone reductase (modulator of drug activity B)
KPMDMHFH_01052 1.63e-46 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-quinone reductase (modulator of drug activity B)
KPMDMHFH_01053 4.26e-132 - - - K - - - Transcriptional regulator
KPMDMHFH_01054 4.26e-230 jag - - S ko:K06346 - ko00000 RNA-binding protein
KPMDMHFH_01055 4.24e-187 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPMDMHFH_01056 9.69e-72 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KPMDMHFH_01057 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
KPMDMHFH_01058 3.51e-294 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KPMDMHFH_01059 9.29e-168 fasA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulator of the LytR AlgR family
KPMDMHFH_01060 3.57e-284 fasC 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KPMDMHFH_01061 1.16e-260 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KPMDMHFH_01062 2.99e-193 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KPMDMHFH_01063 9.69e-292 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 signal transduction protein with a C-terminal ATPase domain
KPMDMHFH_01064 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KPMDMHFH_01065 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KPMDMHFH_01066 1.37e-155 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KPMDMHFH_01067 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KPMDMHFH_01068 1.34e-65 - - - S - - - Protein of unknown function (DUF3397)
KPMDMHFH_01069 2.76e-115 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KPMDMHFH_01070 1.02e-163 - - - S - - - Mitochondrial biogenesis AIM24
KPMDMHFH_01071 1.08e-287 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KPMDMHFH_01072 4.79e-100 - 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
KPMDMHFH_01073 8.2e-102 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KPMDMHFH_01074 1.58e-138 XK27_09620 - - S - - - FMN reductase (NADPH) activity
KPMDMHFH_01075 3.61e-307 XK27_09615 - - C ko:K19784 - ko00000 reductase
KPMDMHFH_01076 1.49e-181 nirC_1 - - P - - - Formate nitrite transporter
KPMDMHFH_01077 2.37e-124 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
KPMDMHFH_01078 7.25e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KPMDMHFH_01079 2.76e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KPMDMHFH_01080 3.26e-152 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
KPMDMHFH_01081 1.99e-122 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KPMDMHFH_01082 6.63e-281 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KPMDMHFH_01083 3.08e-109 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KPMDMHFH_01084 1.19e-176 - - - S ko:K07025 - ko00000 HAD hydrolase, family IA, variant
KPMDMHFH_01085 3.87e-201 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
KPMDMHFH_01089 4.02e-116 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KPMDMHFH_01090 4.45e-86 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KPMDMHFH_01091 3.15e-146 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KPMDMHFH_01092 9.14e-146 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPMDMHFH_01094 2.86e-72 ytpP - - CO - - - Thioredoxin
KPMDMHFH_01096 1.02e-257 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
KPMDMHFH_01097 2.36e-170 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPMDMHFH_01098 2.49e-129 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
KPMDMHFH_01100 3.93e-141 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
KPMDMHFH_01101 1.05e-36 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
KPMDMHFH_01102 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPMDMHFH_01103 3.39e-226 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
KPMDMHFH_01104 7.17e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
KPMDMHFH_01105 1.8e-90 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
KPMDMHFH_01106 5e-21 - - - NU - - - Type II secretory pathway pseudopilin
KPMDMHFH_01107 2.8e-91 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
KPMDMHFH_01108 1.1e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
KPMDMHFH_01109 2.1e-178 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KPMDMHFH_01110 1.05e-222 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KPMDMHFH_01111 1.37e-91 - - - S - - - cog cog4699
KPMDMHFH_01112 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPMDMHFH_01113 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPMDMHFH_01114 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KPMDMHFH_01115 1.65e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KPMDMHFH_01116 1.73e-246 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KPMDMHFH_01117 8.29e-100 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KPMDMHFH_01118 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
KPMDMHFH_01119 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
KPMDMHFH_01120 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
KPMDMHFH_01121 1.87e-76 asp - - S - - - cog cog1302
KPMDMHFH_01122 4.04e-285 norN - - V - - - Mate efflux family protein
KPMDMHFH_01123 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
KPMDMHFH_01124 0.000366 yebC - - M - - - Membrane
KPMDMHFH_01126 0.0 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KPMDMHFH_01127 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KPMDMHFH_01128 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
KPMDMHFH_01129 0.0 treP 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KPMDMHFH_01130 7.1e-162 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
KPMDMHFH_01131 1.94e-123 ywlG - - S - - - Belongs to the UPF0340 family
KPMDMHFH_01134 1.02e-82 - - - S - - - TIR domain
KPMDMHFH_01135 8.87e-39 - - - - - - - -
KPMDMHFH_01136 2.85e-37 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KPMDMHFH_01137 6.42e-61 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KPMDMHFH_01138 5.98e-212 - - - - - - - -
KPMDMHFH_01142 2.94e-60 - - - L - - - the current gene model (or a revised gene model) may contain a
KPMDMHFH_01144 2.89e-25 - - - S - - - CAAX protease self-immunity
KPMDMHFH_01146 5.93e-204 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KPMDMHFH_01147 3.29e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
KPMDMHFH_01148 1.29e-126 - - - V - - - ABC transporter transmembrane region
KPMDMHFH_01149 1.54e-96 - - - P - - - Protein conserved in bacteria
KPMDMHFH_01150 3.59e-70 - - - - - - - -
KPMDMHFH_01152 4.22e-42 - - - - - - - -
KPMDMHFH_01153 5.48e-55 - - - - - - - -
KPMDMHFH_01154 3.18e-290 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPMDMHFH_01155 8.68e-159 - - - K - - - Peptidase S24-like
KPMDMHFH_01156 4.68e-180 - - - E - - - IrrE N-terminal-like domain
KPMDMHFH_01157 1.12e-169 - - - L - - - the current gene model (or a revised gene model) may contain a
KPMDMHFH_01158 2.45e-66 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
KPMDMHFH_01159 4.75e-57 - - - - - - - -
KPMDMHFH_01160 1.44e-93 - - - - - - - -
KPMDMHFH_01161 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
KPMDMHFH_01162 2.24e-282 - - - K - - - Replication initiation factor
KPMDMHFH_01163 1.34e-44 - - - - - - - -
KPMDMHFH_01164 1.71e-112 - - - - - - - -
KPMDMHFH_01165 2e-204 - - - S - - - Conjugative transposon protein TcpC
KPMDMHFH_01166 7.96e-45 - - - - - - - -
KPMDMHFH_01167 4.9e-86 - - - S - - - TcpE family
KPMDMHFH_01168 0.0 yddE - - S - - - AAA-like domain
KPMDMHFH_01169 0.0 - - - - - - - -
KPMDMHFH_01170 4.45e-42 - - - - - - - -
KPMDMHFH_01171 6.97e-220 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
KPMDMHFH_01172 6.73e-22 - - - - - - - -
KPMDMHFH_01173 4.21e-235 - - - L - - - Phage integrase family
KPMDMHFH_01174 4.93e-211 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
KPMDMHFH_01176 1.66e-306 - - - H - - - gamma-glutamylcysteine synthetase
KPMDMHFH_01177 3.03e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
KPMDMHFH_01178 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPMDMHFH_01179 1.63e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KPMDMHFH_01180 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPMDMHFH_01181 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KPMDMHFH_01182 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KPMDMHFH_01183 9.83e-148 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KPMDMHFH_01184 8.65e-293 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KPMDMHFH_01185 8.47e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KPMDMHFH_01186 9.89e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
KPMDMHFH_01187 7e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KPMDMHFH_01188 7.15e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPMDMHFH_01189 5.88e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KPMDMHFH_01190 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPMDMHFH_01191 2.03e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPMDMHFH_01192 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPMDMHFH_01193 5.67e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPMDMHFH_01194 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KPMDMHFH_01195 3.08e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPMDMHFH_01196 6.2e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KPMDMHFH_01197 4.35e-94 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KPMDMHFH_01198 1.91e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KPMDMHFH_01199 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KPMDMHFH_01200 8.13e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KPMDMHFH_01201 1.45e-195 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPMDMHFH_01202 6e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KPMDMHFH_01203 2.13e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KPMDMHFH_01204 3.17e-142 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPMDMHFH_01205 4.29e-64 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KPMDMHFH_01206 4.89e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KPMDMHFH_01207 0.0 XK27_09800 - - I - - - Acyltransferase
KPMDMHFH_01208 3.45e-47 - - - S - - - MORN repeat protein
KPMDMHFH_01209 3.12e-104 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPMDMHFH_01210 3.87e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KPMDMHFH_01211 9.55e-116 flaR - - F - - - topology modulation protein
KPMDMHFH_01212 1.75e-105 - - - S - - - Short repeat of unknown function (DUF308)
KPMDMHFH_01213 1.36e-115 - - - K - - - sequence-specific DNA binding
KPMDMHFH_01214 1.96e-208 - - - L - - - Replication initiation factor
KPMDMHFH_01215 1.95e-26 - - - S - - - Domain of unknown function (DUF3173)
KPMDMHFH_01216 1.44e-276 - - - L - - - Belongs to the 'phage' integrase family
KPMDMHFH_01218 3.43e-299 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
KPMDMHFH_01219 1.73e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KPMDMHFH_01220 9.75e-59 yrzL - - S - - - Belongs to the UPF0297 family
KPMDMHFH_01221 5.68e-91 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPMDMHFH_01222 1.34e-62 yrzB - - S - - - Belongs to the UPF0473 family
KPMDMHFH_01223 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
KPMDMHFH_01224 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
KPMDMHFH_01225 7.68e-20 - - - - - - - -
KPMDMHFH_01226 4.23e-115 - - - K - - - acetyltransferase
KPMDMHFH_01227 8.87e-150 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPMDMHFH_01228 3.38e-158 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
KPMDMHFH_01229 3.6e-214 XK27_01785 - - S - - - cog cog1284
KPMDMHFH_01230 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KPMDMHFH_01232 1.08e-304 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KPMDMHFH_01233 1.01e-95 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KPMDMHFH_01234 9.42e-133 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KPMDMHFH_01235 1.75e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
KPMDMHFH_01236 8.74e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KPMDMHFH_01237 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KPMDMHFH_01238 1.37e-164 - - - P ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KPMDMHFH_01239 1.18e-292 - - - - - - - -
KPMDMHFH_01240 0.0 - - - L - - - DNA integration
KPMDMHFH_01242 9.72e-254 - - - L - - - Replication initiation factor
KPMDMHFH_01243 1.54e-80 - - - - - - - -
KPMDMHFH_01246 6.74e-80 - - - - - - - -
KPMDMHFH_01247 0.0 - - - K - - - Transcriptional regulator
KPMDMHFH_01248 4.56e-275 - - - KLT - - - Protein tyrosine kinase
KPMDMHFH_01249 8.84e-80 - - - L - - - An automated process has identified a potential problem with this gene model
KPMDMHFH_01250 1.02e-236 - - - L - - - Transposase
KPMDMHFH_01251 4.67e-77 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
KPMDMHFH_01252 4.19e-46 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KPMDMHFH_01253 1.07e-217 - - - T - - - Diguanylate cyclase
KPMDMHFH_01254 1.01e-193 - - - M - - - COG0463, glycosyltransferases involved in cell wall biogenesis
KPMDMHFH_01255 0.0 - 2.4.1.12 GT2 M ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
KPMDMHFH_01256 0.0 - - - - - - - -
KPMDMHFH_01260 3.9e-149 XK27_06885 - - L - - - hydrolase
KPMDMHFH_01261 8.74e-69 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator, PadR family
KPMDMHFH_01262 3.47e-98 - - - S - - - Protein of unknown function (DUF1700)
KPMDMHFH_01263 7.24e-145 - - - S - - - Putative adhesin
KPMDMHFH_01264 1.32e-262 XK27_06930 - - V ko:K01421 - ko00000 domain protein
KPMDMHFH_01265 1.69e-125 XK27_06935 - - K - - - transcriptional regulator
KPMDMHFH_01266 1.32e-71 XK27_04840 - - M ko:K08987 - ko00000 Membrane
KPMDMHFH_01267 5.32e-13 - - - - - - - -
KPMDMHFH_01268 1.25e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPMDMHFH_01269 6.16e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
KPMDMHFH_01270 1.35e-314 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KPMDMHFH_01271 1.77e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KPMDMHFH_01272 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KPMDMHFH_01273 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KPMDMHFH_01274 2.58e-130 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
KPMDMHFH_01275 3.27e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KPMDMHFH_01276 0.0 - - - S - - - Bacterial membrane protein, YfhO
KPMDMHFH_01277 1.96e-125 isaA - - M - - - Immunodominant staphylococcal antigen A
KPMDMHFH_01278 3.42e-103 lytE - - M - - - LysM domain protein
KPMDMHFH_01279 4.35e-170 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPMDMHFH_01280 3.85e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPMDMHFH_01281 2.6e-193 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPMDMHFH_01282 2.68e-118 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPMDMHFH_01283 2.87e-167 - - - S ko:K15539 - ko00000 sequence-specific DNA binding
KPMDMHFH_01284 1.02e-297 ymfH - - S - - - Peptidase M16
KPMDMHFH_01285 5.65e-295 albE - - S - - - Peptidase M16
KPMDMHFH_01286 5.94e-75 yaaA - - S - - - S4 domain protein YaaA
KPMDMHFH_01287 3.56e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPMDMHFH_01288 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KPMDMHFH_01289 1.12e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
KPMDMHFH_01290 3.8e-193 XK27_10395 - - S - - - membrane
KPMDMHFH_01291 0.0 ykpA - - S - - - abc transporter atp-binding protein
KPMDMHFH_01292 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
KPMDMHFH_01296 9.43e-155 yoaK - - S - - - Protein of unknown function (DUF1275)
KPMDMHFH_01297 2.89e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPMDMHFH_01298 2.48e-275 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KPMDMHFH_01299 2.28e-172 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KPMDMHFH_01300 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPMDMHFH_01301 1.13e-252 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KPMDMHFH_01302 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
KPMDMHFH_01303 7.47e-259 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KPMDMHFH_01304 1.8e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KPMDMHFH_01305 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPMDMHFH_01306 1.87e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KPMDMHFH_01307 3.9e-79 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KPMDMHFH_01308 1.36e-05 - - - - - - - -
KPMDMHFH_01309 1.35e-300 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
KPMDMHFH_01310 9.1e-299 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KPMDMHFH_01311 3.15e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
KPMDMHFH_01312 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPMDMHFH_01313 4.11e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KPMDMHFH_01314 6.69e-111 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
KPMDMHFH_01315 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KPMDMHFH_01316 2.14e-140 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
KPMDMHFH_01317 3.47e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
KPMDMHFH_01318 1.55e-143 XK27_04065 - - S ko:K04767 - ko00000 CBS domain
KPMDMHFH_01319 4.6e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KPMDMHFH_01320 5.4e-175 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KPMDMHFH_01321 1.64e-184 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KPMDMHFH_01322 1.65e-189 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KPMDMHFH_01323 1.7e-268 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KPMDMHFH_01324 1.51e-62 ylbG - - S - - - UPF0298 protein
KPMDMHFH_01325 9.16e-95 ylbF - - S - - - Belongs to the UPF0342 family
KPMDMHFH_01326 3.75e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KPMDMHFH_01327 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KPMDMHFH_01328 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
KPMDMHFH_01329 0.0 - 3.2.1.26, 3.2.1.65 GH32 G ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KPMDMHFH_01330 1.3e-283 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KPMDMHFH_01331 1.39e-255 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
KPMDMHFH_01332 0.0 pacL - - P - - - cation transport ATPase
KPMDMHFH_01333 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KPMDMHFH_01334 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPMDMHFH_01335 6.8e-129 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KPMDMHFH_01336 5.68e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KPMDMHFH_01337 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPMDMHFH_01338 2.19e-56 ylxQ - - J - - - ribosomal protein
KPMDMHFH_01339 6.47e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
KPMDMHFH_01340 1.51e-260 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KPMDMHFH_01341 1.75e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KPMDMHFH_01342 5.98e-247 brpA - - K - - - Transcriptional
KPMDMHFH_01343 1.29e-117 XK27_05885 2.3.1.82 - M ko:K18816 - br01600,ko00000,ko01000,ko01504 phosphinothricin N-acetyltransferase activity
KPMDMHFH_01344 1.79e-100 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
KPMDMHFH_01345 7.03e-316 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
KPMDMHFH_01346 5.08e-197 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
KPMDMHFH_01347 1.98e-176 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
KPMDMHFH_01348 3.33e-221 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KPMDMHFH_01349 9.8e-168 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
KPMDMHFH_01350 8.01e-202 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
KPMDMHFH_01351 6.62e-87 manO - - S - - - Protein conserved in bacteria
KPMDMHFH_01352 1.39e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KPMDMHFH_01353 6.23e-162 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
KPMDMHFH_01354 1.22e-216 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
KPMDMHFH_01355 7.55e-82 manO - - S - - - protein conserved in bacteria
KPMDMHFH_01356 1.96e-297 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPMDMHFH_01357 2.7e-139 - - - - - - - -
KPMDMHFH_01358 1.45e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KPMDMHFH_01359 2.54e-212 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KPMDMHFH_01360 5.59e-271 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
KPMDMHFH_01361 5.84e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPMDMHFH_01362 0.0 covS - - T - - - Histidine kinase
KPMDMHFH_01363 1.33e-158 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPMDMHFH_01364 4.64e-118 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
KPMDMHFH_01365 1.23e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
KPMDMHFH_01366 3.9e-298 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
KPMDMHFH_01367 3.28e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
KPMDMHFH_01368 3.54e-191 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
KPMDMHFH_01369 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_01370 4.45e-122 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
KPMDMHFH_01371 1.2e-201 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
KPMDMHFH_01372 4.9e-266 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KPMDMHFH_01373 1.04e-151 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_01374 8.45e-241 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KPMDMHFH_01375 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KPMDMHFH_01376 4.91e-210 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
KPMDMHFH_01377 7.14e-194 - - - ET ko:K02030 - ko00000,ko00002,ko02000 amino acid transport
KPMDMHFH_01378 1.39e-169 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPMDMHFH_01379 2.77e-175 nikQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport protein
KPMDMHFH_01380 1.67e-225 - - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biosynthesis protein CbiM
KPMDMHFH_01381 9.51e-202 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KPMDMHFH_01382 4.71e-142 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KPMDMHFH_01383 1.83e-169 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KPMDMHFH_01384 2.74e-101 ureE - - O ko:K03187 - ko00000 enzyme active site formation
KPMDMHFH_01385 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KPMDMHFH_01386 3.78e-72 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
KPMDMHFH_01387 1.02e-61 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
KPMDMHFH_01388 2.16e-124 ureI - - S ko:K03191 ko05120,map05120 ko00000,ko00001,ko02000 AmiS/UreI family transporter
KPMDMHFH_01389 4.49e-316 - - - S - - - Domain of unknown function (DUF4173)
KPMDMHFH_01390 3.14e-72 yhaI - - L - - - Membrane
KPMDMHFH_01391 0.0 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KPMDMHFH_01392 2.48e-198 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KPMDMHFH_01393 5.5e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
KPMDMHFH_01394 4.62e-116 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPMDMHFH_01395 2.17e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KPMDMHFH_01396 7.73e-312 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
KPMDMHFH_01397 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
KPMDMHFH_01398 9.94e-20 yidD - - M ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
KPMDMHFH_01399 1.23e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KPMDMHFH_01400 1.15e-123 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPMDMHFH_01401 8.23e-157 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPMDMHFH_01402 4.25e-168 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KPMDMHFH_01403 1.23e-111 ykuL - - S - - - CBS domain
KPMDMHFH_01404 3.06e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
KPMDMHFH_01405 6.39e-234 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KPMDMHFH_01406 2.92e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KPMDMHFH_01407 2.31e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
KPMDMHFH_01408 8.96e-117 - - - K - - - transcriptional regulator
KPMDMHFH_01409 1.93e-308 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KPMDMHFH_01411 9.49e-143 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KPMDMHFH_01412 2.55e-121 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
KPMDMHFH_01413 2.19e-165 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPMDMHFH_01414 1.58e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KPMDMHFH_01415 2.63e-212 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPMDMHFH_01416 1.17e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPMDMHFH_01417 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KPMDMHFH_01418 2.87e-112 - - - K - - - histone acetyltransferase HPA2 and related acetyltransferases
KPMDMHFH_01419 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KPMDMHFH_01420 4.8e-28 XK27_11680 - - - - - - -
KPMDMHFH_01421 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
KPMDMHFH_01422 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KPMDMHFH_01423 1.45e-281 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KPMDMHFH_01424 3.97e-66 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KPMDMHFH_01425 1.78e-123 ypsA - - S - - - Belongs to the UPF0398 family
KPMDMHFH_01426 2.86e-140 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KPMDMHFH_01427 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KPMDMHFH_01428 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KPMDMHFH_01429 1.42e-97 yhaH - - S - - - Protein of unknown function (DUF805)
KPMDMHFH_01430 2.81e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KPMDMHFH_01431 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPMDMHFH_01432 5.02e-274 - - - V - - - FtsX-like permease family
KPMDMHFH_01433 2.58e-155 - - - V - - - abc transporter atp-binding protein
KPMDMHFH_01434 1.67e-160 mta - - K ko:K21743 - ko00000,ko03000 Transcriptional
KPMDMHFH_01435 3.6e-42 - - - S - - - Protein of unknown function (DUF3021)
KPMDMHFH_01436 9.49e-98 - - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
KPMDMHFH_01437 2.2e-171 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
KPMDMHFH_01438 1.14e-193 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_01439 1.11e-294 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
KPMDMHFH_01440 9.49e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KPMDMHFH_01441 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KPMDMHFH_01442 1.79e-169 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
KPMDMHFH_01443 6.61e-188 cof - - S - - - Sucrose-6F-phosphate phosphohydrolase
KPMDMHFH_01444 1.1e-92 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
KPMDMHFH_01445 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KPMDMHFH_01446 1.05e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
KPMDMHFH_01447 2.73e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KPMDMHFH_01448 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KPMDMHFH_01449 8.51e-210 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KPMDMHFH_01450 5.41e-73 WQ51_06355 - - S - - - TM2 domain
KPMDMHFH_01451 4.19e-60 - - - - - - - -
KPMDMHFH_01453 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KPMDMHFH_01454 7.72e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KPMDMHFH_01455 6.07e-183 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_01456 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
KPMDMHFH_01457 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KPMDMHFH_01458 6.62e-296 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KPMDMHFH_01459 5.02e-185 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KPMDMHFH_01460 3.56e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KPMDMHFH_01461 1.42e-60 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
KPMDMHFH_01462 2.37e-161 yeeN - - K - - - transcriptional regulatory protein
KPMDMHFH_01463 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
KPMDMHFH_01464 8.7e-199 Z012_04635 - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KPMDMHFH_01465 1.4e-280 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
KPMDMHFH_01466 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KPMDMHFH_01467 6.62e-138 - - - L - - - Transposase IS116 IS110 IS902
KPMDMHFH_01468 2.58e-77 B4168_4126 - - L ko:K07493 - ko00000 MULE transposase domain
KPMDMHFH_01469 7.78e-21 - - - L - - - An automated process has identified a potential problem with this gene model
KPMDMHFH_01470 2.58e-77 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 sorbitol-specific, IIA component
KPMDMHFH_01471 4.63e-228 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS sorbitol transporter subunit IIB
KPMDMHFH_01472 6.32e-124 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system glucitol sorbitol-specific
KPMDMHFH_01473 2.45e-109 gutM - - K ko:K02466 - ko00000 phosphoenolpyruvate-dependent sugar phosphotransferase system
KPMDMHFH_01474 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
KPMDMHFH_01475 4.62e-182 sorD 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KPMDMHFH_01476 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KPMDMHFH_01477 1.79e-196 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
KPMDMHFH_01478 0.0 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
KPMDMHFH_01479 1.81e-202 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
KPMDMHFH_01480 7.36e-165 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_01481 3.43e-173 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPMDMHFH_01482 8.68e-93 adcR - - K - - - transcriptional
KPMDMHFH_01483 2.41e-233 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPMDMHFH_01484 1.29e-199 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KPMDMHFH_01485 3.52e-34 - - - - - - - -
KPMDMHFH_01486 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
KPMDMHFH_01487 4.28e-97 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KPMDMHFH_01488 1.57e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KPMDMHFH_01489 1.98e-297 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
KPMDMHFH_01490 1.65e-176 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KPMDMHFH_01491 3.82e-243 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
KPMDMHFH_01492 7.31e-166 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KPMDMHFH_01494 1.75e-195 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KPMDMHFH_01495 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPMDMHFH_01496 3e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_01497 4.34e-61 - - - - - - - -
KPMDMHFH_01498 1.01e-165 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KPMDMHFH_01501 1.88e-66 - - - - - - - -
KPMDMHFH_01502 8.72e-188 agrC 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KPMDMHFH_01503 6.47e-156 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
KPMDMHFH_01506 0.0 - - - D - - - nuclear chromosome segregation
KPMDMHFH_01507 1.84e-126 - - - V - - - VanZ like family
KPMDMHFH_01508 3.52e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KPMDMHFH_01509 5.88e-242 XK27_00055 - - P - - - Major Facilitator
KPMDMHFH_01510 1.1e-144 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KPMDMHFH_01511 5.97e-145 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KPMDMHFH_01512 3.71e-300 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KPMDMHFH_01513 0.0 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
KPMDMHFH_01514 2.35e-96 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KPMDMHFH_01515 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KPMDMHFH_01516 6.05e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
KPMDMHFH_01517 0.0 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KPMDMHFH_01518 4.61e-168 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KPMDMHFH_01519 8.61e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
KPMDMHFH_01520 1.52e-98 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KPMDMHFH_01521 3.55e-109 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
KPMDMHFH_01522 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KPMDMHFH_01523 1.24e-101 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KPMDMHFH_01524 1.81e-292 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KPMDMHFH_01525 7.93e-177 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
KPMDMHFH_01526 3.1e-112 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
KPMDMHFH_01528 3.14e-190 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KPMDMHFH_01529 3.14e-179 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_01530 1.44e-165 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPMDMHFH_01531 2.59e-311 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KPMDMHFH_01532 5.93e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
KPMDMHFH_01533 7.7e-75 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
KPMDMHFH_01534 1.94e-289 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
KPMDMHFH_01535 1.89e-187 XK27_00835 - - S - - - hydrolases of the HAD superfamily
KPMDMHFH_01536 6.72e-186 XK27_00115 - - K - - - Acetyltransferase GNAT family
KPMDMHFH_01537 2.05e-90 ywiB - - S - - - Domain of unknown function (DUF1934)
KPMDMHFH_01538 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
KPMDMHFH_01539 2.36e-166 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
KPMDMHFH_01540 3.65e-196 - - - S - - - Calcineurin-like phosphoesterase
KPMDMHFH_01541 9.18e-265 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KPMDMHFH_01542 4.4e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KPMDMHFH_01543 8.67e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
KPMDMHFH_01544 8.45e-211 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KPMDMHFH_01545 3.39e-118 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KPMDMHFH_01546 2.22e-234 XK27_05220 - - S - - - permease
KPMDMHFH_01547 1.78e-283 XK27_05225 - - G - - - COG0457 FOG TPR repeat
KPMDMHFH_01548 2.19e-124 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KPMDMHFH_01549 0.0 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
KPMDMHFH_01550 2.29e-294 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KPMDMHFH_01551 4.23e-115 ebsA - - S - - - Family of unknown function (DUF5322)
KPMDMHFH_01552 2.36e-38 XK27_09115 - - M - - - LysM domain
KPMDMHFH_01553 3.39e-155 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KPMDMHFH_01554 1.1e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KPMDMHFH_01555 2.36e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KPMDMHFH_01556 1.82e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KPMDMHFH_01557 1.26e-108 XK27_03610 - - K - - - Gnat family
KPMDMHFH_01558 5.49e-119 yybC - - - - - - -
KPMDMHFH_01559 1.38e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
KPMDMHFH_01560 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
KPMDMHFH_01561 6.03e-140 ung2 - - L - - - Uracil-DNA glycosylase
KPMDMHFH_01562 0.0 - - - V - - - Glucan-binding protein C
KPMDMHFH_01563 0.0 - - - V ko:K13732 ko05100,map05100 ko00000,ko00001 Glucan-binding protein C
KPMDMHFH_01564 5.87e-156 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KPMDMHFH_01565 1.75e-296 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
KPMDMHFH_01566 6.6e-124 - - - S - - - Protein of unknown function (DUF1697)
KPMDMHFH_01567 2.8e-189 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KPMDMHFH_01568 1.81e-63 - - - S ko:K03744 - ko00000 LemA family
KPMDMHFH_01569 4.38e-224 - - - P - - - Chloride transporter, ClC family
KPMDMHFH_01570 1.75e-167 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
KPMDMHFH_01571 9.75e-169 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
KPMDMHFH_01572 2.14e-314 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KPMDMHFH_01573 1.01e-169 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
KPMDMHFH_01574 2.52e-143 capA - - M - - - biosynthesis protein
KPMDMHFH_01575 3.69e-153 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
KPMDMHFH_01576 0.0 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KPMDMHFH_01577 2e-284 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 group 1 family protein
KPMDMHFH_01578 1.72e-267 - - - M - - - Glycosyltransferase, group 1 family protein
KPMDMHFH_01579 5.71e-154 - - - M - - - Domain of unknown function (DUF1919)
KPMDMHFH_01580 2.46e-206 - - - M - - - Glycosyltransferase, group 2 family protein
KPMDMHFH_01581 1.25e-194 - - - M - - - Glycosyltransferase like family 2
KPMDMHFH_01582 5.82e-221 - - - - - - - -
KPMDMHFH_01583 1.15e-315 wzx - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KPMDMHFH_01584 2.4e-201 - - - S - - - Acyltransferase family
KPMDMHFH_01585 5.82e-274 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KPMDMHFH_01586 7.49e-236 wefC - - M - - - Stealth protein CR2, conserved region 2
KPMDMHFH_01587 7.46e-237 - - - M - - - transferase activity, transferring glycosyl groups
KPMDMHFH_01589 5.69e-195 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
KPMDMHFH_01590 9.54e-140 XK27_06100 - - G - - - Belongs to the phosphoglycerate mutase family
KPMDMHFH_01591 1.3e-138 - - - G - - - Belongs to the phosphoglycerate mutase family
KPMDMHFH_01592 2.8e-141 - - - G - - - Belongs to the phosphoglycerate mutase family
KPMDMHFH_01593 4.6e-252 XK27_12525 - - S - - - hmm pf01594
KPMDMHFH_01594 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KPMDMHFH_01595 2.35e-52 - - - S - - - granule-associated protein
KPMDMHFH_01596 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
KPMDMHFH_01597 3.24e-132 - - - E - - - Lysophospholipase L1 and related esterases
KPMDMHFH_01598 2.93e-198 - - - S - - - Phospholipase, patatin family
KPMDMHFH_01599 4.58e-230 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
KPMDMHFH_01600 3.15e-315 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
KPMDMHFH_01601 6.08e-274 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPMDMHFH_01602 9.06e-151 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPMDMHFH_01603 2.07e-300 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KPMDMHFH_01604 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
KPMDMHFH_01605 9.63e-289 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KPMDMHFH_01606 9.01e-265 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
KPMDMHFH_01607 1.45e-234 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
KPMDMHFH_01608 1.14e-231 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KPMDMHFH_01609 2.25e-247 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KPMDMHFH_01610 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
KPMDMHFH_01611 0.0 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
KPMDMHFH_01612 0.0 amiA 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-Acetylmuramoyl-L-alanine amidase
KPMDMHFH_01613 0.0 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
KPMDMHFH_01614 2.79e-195 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
KPMDMHFH_01615 2.38e-293 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
KPMDMHFH_01616 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
KPMDMHFH_01617 1.24e-154 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KPMDMHFH_01618 5.62e-33 tatA - - U ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
KPMDMHFH_01619 2.37e-270 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KPMDMHFH_01620 1.5e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_01621 5.52e-316 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_01622 4.11e-292 malX - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPMDMHFH_01623 4.64e-200 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KPMDMHFH_01624 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
KPMDMHFH_01625 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KPMDMHFH_01627 8.8e-239 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
KPMDMHFH_01628 3.75e-248 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KPMDMHFH_01629 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
KPMDMHFH_01630 5.43e-148 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KPMDMHFH_01631 2.49e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPMDMHFH_01632 7.48e-193 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPMDMHFH_01633 3.12e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
KPMDMHFH_01634 1.33e-200 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KPMDMHFH_01635 1.7e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
KPMDMHFH_01636 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
KPMDMHFH_01637 3.26e-184 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
KPMDMHFH_01638 4.17e-60 yktA - - S - - - Belongs to the UPF0223 family
KPMDMHFH_01639 3.58e-93 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KPMDMHFH_01640 1.42e-215 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KPMDMHFH_01641 7.77e-191 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KPMDMHFH_01642 0.0 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
KPMDMHFH_01643 7.18e-47 M1-755 - - P ko:K09155 - ko00000 Hemerythrin HHE cation binding domain protein
KPMDMHFH_01644 3.31e-143 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
KPMDMHFH_01645 1.37e-110 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KPMDMHFH_01646 3.14e-177 - - - S - - - haloacid dehalogenase-like hydrolase
KPMDMHFH_01647 1.64e-304 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
KPMDMHFH_01648 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KPMDMHFH_01649 2.36e-305 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
KPMDMHFH_01650 8.07e-313 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KPMDMHFH_01651 1.83e-223 bglC - - K - - - Transcriptional regulator
KPMDMHFH_01652 0.0 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KPMDMHFH_01653 6.58e-105 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_01654 1.32e-189 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
KPMDMHFH_01655 4.51e-303 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
KPMDMHFH_01656 1.24e-144 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPMDMHFH_01657 5.88e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KPMDMHFH_01658 4.81e-226 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KPMDMHFH_01659 2.21e-185 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KPMDMHFH_01660 2.19e-118 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
KPMDMHFH_01661 5.92e-169 - - - S - - - TraX protein
KPMDMHFH_01662 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
KPMDMHFH_01663 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
KPMDMHFH_01664 2.49e-295 dinF - - V - - - Mate efflux family protein
KPMDMHFH_01665 5.4e-225 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
KPMDMHFH_01666 2.33e-200 - - - S - - - von Willebrand factor (vWF) type A domain
KPMDMHFH_01667 0.0 - - - V - - - Type III restriction enzyme, res subunit
KPMDMHFH_01668 1.24e-141 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
KPMDMHFH_01669 1.37e-307 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
KPMDMHFH_01670 1.02e-236 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Dehydrogenase
KPMDMHFH_01671 1.02e-253 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
KPMDMHFH_01672 4.3e-202 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
KPMDMHFH_01673 4.47e-121 - - - K - - - Transcriptional regulator, TetR family
KPMDMHFH_01674 1.73e-91 - - - S - - - Protein of unknown function with HXXEE motif
KPMDMHFH_01675 1.43e-59 - - - - - - - -
KPMDMHFH_01676 6.63e-61 - - - L - - - Transposase
KPMDMHFH_01677 0.0 - - - S - - - Signal peptide protein, YSIRK family
KPMDMHFH_01678 2.22e-163 saeR - - K ko:K10682 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KPMDMHFH_01679 1.26e-225 saeS 2.7.13.3 - T ko:K10681 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KPMDMHFH_01680 6.95e-132 - - - L - - - Transposase
KPMDMHFH_01681 1.02e-12 ywrO - - S ko:K11748 - ko00000,ko02000 general stress protein
KPMDMHFH_01682 3.68e-27 ywrO - - K ko:K11748 - ko00000,ko02000 NAD(P)H dehydrogenase (quinone) activity
KPMDMHFH_01683 1.69e-37 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KPMDMHFH_01684 9e-101 - - - S - - - RDD family
KPMDMHFH_01685 2.18e-101 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KPMDMHFH_01686 1.82e-189 - - - S - - - Protein of unknown function DUF262
KPMDMHFH_01687 3.62e-249 - - - S - - - Protein of unknown function DUF262
KPMDMHFH_01688 5.22e-167 - - - L ko:K07482 - ko00000 Integrase
KPMDMHFH_01689 0.0 - 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KPMDMHFH_01690 9.5e-275 - - - GKT - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KPMDMHFH_01691 1.45e-56 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG3414 Phosphotransferase system galactitol-specific IIB component
KPMDMHFH_01692 3.67e-282 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KPMDMHFH_01693 3.85e-156 tktN 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 1-deoxy-D-xylulose-5-phosphate synthase
KPMDMHFH_01694 3.89e-156 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
KPMDMHFH_01695 1.31e-188 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KPMDMHFH_01696 9.02e-154 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
KPMDMHFH_01697 4.98e-24 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
KPMDMHFH_01698 1.3e-126 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
KPMDMHFH_01699 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KPMDMHFH_01700 9e-48 - - - P ko:K10716 - ko00000,ko02000 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KPMDMHFH_01701 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
KPMDMHFH_01702 2.27e-192 - - - L - - - PFAM Integrase catalytic region
KPMDMHFH_01703 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPMDMHFH_01704 8.38e-113 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
KPMDMHFH_01705 0.0 clsA_1 - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPMDMHFH_01706 2.24e-160 - - - L - - - DNA alkylation repair enzyme
KPMDMHFH_01707 2.49e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPMDMHFH_01708 1.81e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPMDMHFH_01709 1.25e-158 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KPMDMHFH_01710 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KPMDMHFH_01711 2.03e-118 - - - S - - - Protein of unknown function (DUF3278)
KPMDMHFH_01712 3.7e-32 WQ51_00220 - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
KPMDMHFH_01713 3.95e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KPMDMHFH_01714 1.46e-118 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPMDMHFH_01715 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPMDMHFH_01717 3.78e-74 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
KPMDMHFH_01718 8.14e-302 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KPMDMHFH_01720 2.83e-110 - - - S - - - ECF-type riboflavin transporter, S component
KPMDMHFH_01721 3.99e-197 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
KPMDMHFH_01722 9.29e-108 - - - S - - - ECF-type riboflavin transporter, S component
KPMDMHFH_01723 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
KPMDMHFH_01724 0.0 noxE - - P - - - NADH oxidase
KPMDMHFH_01725 2.92e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KPMDMHFH_01726 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPMDMHFH_01727 3.1e-169 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
KPMDMHFH_01728 3.16e-95 ywkD - - E ko:K08234 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
KPMDMHFH_01729 3.82e-209 ypuA - - S - - - secreted protein
KPMDMHFH_01730 3.08e-20 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
KPMDMHFH_01731 9.9e-259 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
KPMDMHFH_01732 3.52e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
KPMDMHFH_01733 2.09e-216 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KPMDMHFH_01734 1.44e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
KPMDMHFH_01735 1.52e-194 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
KPMDMHFH_01736 2.31e-233 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KPMDMHFH_01737 4.93e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KPMDMHFH_01738 7.92e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPMDMHFH_01739 3.36e-185 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KPMDMHFH_01740 1.11e-136 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KPMDMHFH_01741 9.36e-294 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KPMDMHFH_01742 1.5e-228 - - - S - - - 37-kD nucleoid-associated bacterial protein
KPMDMHFH_01743 3.57e-127 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
KPMDMHFH_01744 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
KPMDMHFH_01745 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
KPMDMHFH_01746 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPMDMHFH_01747 2.07e-301 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
KPMDMHFH_01748 7.07e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPMDMHFH_01749 2.87e-307 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPMDMHFH_01750 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
KPMDMHFH_01751 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
KPMDMHFH_01753 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPMDMHFH_01754 4.05e-209 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
KPMDMHFH_01755 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
KPMDMHFH_01756 7.19e-119 - - - S - - - ECF transporter, substrate-specific component
KPMDMHFH_01757 3.37e-117 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPMDMHFH_01758 1.72e-144 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
KPMDMHFH_01759 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KPMDMHFH_01760 2.39e-154 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPMDMHFH_01761 5.01e-310 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KPMDMHFH_01762 4.36e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KPMDMHFH_01763 4.78e-220 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KPMDMHFH_01764 3.21e-136 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
KPMDMHFH_01765 1.73e-290 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KPMDMHFH_01766 2.03e-144 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KPMDMHFH_01767 1e-83 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KPMDMHFH_01768 4.33e-239 - - - S ko:K07335 - ko00000 membrane
KPMDMHFH_01769 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KPMDMHFH_01770 1.53e-243 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KPMDMHFH_01771 3.34e-217 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KPMDMHFH_01772 3.05e-146 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
KPMDMHFH_01773 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KPMDMHFH_01774 1.32e-106 ypmB - - S - - - Protein conserved in bacteria
KPMDMHFH_01775 1.15e-273 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
KPMDMHFH_01776 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KPMDMHFH_01778 1.21e-253 pmrB - - EGP - - - Major Facilitator Superfamily
KPMDMHFH_01779 9.11e-84 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
KPMDMHFH_01780 4.52e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KPMDMHFH_01781 7.04e-107 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
KPMDMHFH_01782 5.05e-172 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KPMDMHFH_01783 1.61e-122 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KPMDMHFH_01784 8.82e-312 - - - D - - - nuclear chromosome segregation
KPMDMHFH_01785 3.12e-175 yejC - - S - - - cyclic nucleotide-binding protein
KPMDMHFH_01786 1.03e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KPMDMHFH_01787 5.25e-233 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KPMDMHFH_01788 4.01e-206 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KPMDMHFH_01789 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KPMDMHFH_01790 5.2e-187 XK27_10720 - - D - - - peptidase activity
KPMDMHFH_01791 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KPMDMHFH_01794 3.25e-212 yeiH - - S - - - Membrane
KPMDMHFH_01795 9.73e-165 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
KPMDMHFH_01796 5.13e-213 cpsY - - K - - - Transcriptional regulator
KPMDMHFH_01797 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KPMDMHFH_01798 7.1e-78 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
KPMDMHFH_01799 4.78e-135 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_01800 7.5e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_01801 4.34e-200 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KPMDMHFH_01802 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPMDMHFH_01803 3.55e-67 - - - - - - - -
KPMDMHFH_01804 2.51e-61 - - - - - - - -
KPMDMHFH_01805 2.33e-239 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
KPMDMHFH_01806 1.41e-129 - - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KPMDMHFH_01807 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KPMDMHFH_01808 1.5e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
KPMDMHFH_01809 3.35e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KPMDMHFH_01810 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KPMDMHFH_01811 1.33e-111 - - - - ko:K16788 - ko00000,ko02000 -
KPMDMHFH_01812 6.7e-119 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
KPMDMHFH_01813 2.14e-164 - - - K - - - DNA-binding helix-turn-helix protein
KPMDMHFH_01814 3.44e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KPMDMHFH_01815 7.05e-172 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPMDMHFH_01816 2.24e-209 - - - GK - - - ROK family
KPMDMHFH_01817 3.71e-199 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
KPMDMHFH_01818 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPMDMHFH_01819 1.71e-105 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KPMDMHFH_01820 1.32e-68 - - - V ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KPMDMHFH_01822 2.19e-184 - - - S - - - TraX protein
KPMDMHFH_01823 1.56e-152 yycF1 - - T ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPMDMHFH_01824 2.13e-289 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
KPMDMHFH_01825 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KPMDMHFH_01826 2.71e-285 XK27_05470 - - E - - - Methionine synthase
KPMDMHFH_01827 1.8e-94 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KPMDMHFH_01828 1.08e-57 - - - P - - - Rhodanese-like protein
KPMDMHFH_01829 2.2e-174 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
KPMDMHFH_01831 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KPMDMHFH_01834 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KPMDMHFH_01835 1.9e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
KPMDMHFH_01836 1.4e-89 - - - K - - - Transcriptional regulator, MarR family
KPMDMHFH_01837 5.42e-176 - 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 epimerase
KPMDMHFH_01838 4.1e-164 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_01839 0.0 proWX - - P ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KPMDMHFH_01840 9.83e-141 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
KPMDMHFH_01841 7.99e-183 - - - S - - - Phenazine biosynthesis protein
KPMDMHFH_01842 8.69e-127 - 2.7.7.65 - T ko:K16923,ko:K18967 - ko00000,ko00002,ko01000,ko02000 phosphorelay sensor kinase activity
KPMDMHFH_01843 3.45e-169 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KPMDMHFH_01844 1.78e-201 - - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_01845 2.32e-191 - - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Zeta toxin
KPMDMHFH_01846 1.42e-235 - - - S - - - dextransucrase activity
KPMDMHFH_01847 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
KPMDMHFH_01848 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
KPMDMHFH_01849 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
KPMDMHFH_01850 8.33e-200 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KPMDMHFH_01851 1.7e-127 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KPMDMHFH_01852 1.54e-96 - - - - - - - -
KPMDMHFH_01853 3.77e-105 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
KPMDMHFH_01854 7.14e-299 - - - S - - - dextransucrase activity
KPMDMHFH_01855 9.65e-305 - - - S - - - dextransucrase activity
KPMDMHFH_01857 4.11e-71 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
KPMDMHFH_01858 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
KPMDMHFH_01859 0.0 - - - S - - - dextransucrase activity
KPMDMHFH_01861 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
KPMDMHFH_01862 9.79e-153 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
KPMDMHFH_01863 2.01e-57 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
KPMDMHFH_01864 6.1e-14 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KPMDMHFH_01866 1.34e-12 - - - S - - - Enterocin A Immunity
KPMDMHFH_01867 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KPMDMHFH_01868 2.16e-45 - - - S - - - Immunity protein 41
KPMDMHFH_01869 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
KPMDMHFH_01870 8.92e-32 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
KPMDMHFH_01871 4.06e-286 - - - K - - - Psort location CytoplasmicMembrane, score
KPMDMHFH_01872 5.61e-226 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase
KPMDMHFH_01873 1.58e-120 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase
KPMDMHFH_01874 1.65e-76 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 dihydroxyacetone kinase, phosphotransfer subunit
KPMDMHFH_01875 4.8e-226 XK27_10475 - - S - - - oxidoreductase
KPMDMHFH_01876 7e-250 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 glycerol dehydrogenase
KPMDMHFH_01878 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
KPMDMHFH_01879 1.18e-261 vex1 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
KPMDMHFH_01880 4.31e-141 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_01881 1.59e-304 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
KPMDMHFH_01882 7.15e-148 vncR - - K - - - Response regulator receiver domain protein
KPMDMHFH_01883 1.73e-289 vncS 2.7.13.3 - T ko:K10819 - ko00000,ko01000 Histidine kinase
KPMDMHFH_01884 8.7e-115 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
KPMDMHFH_01885 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 COG0366 Glycosidases
KPMDMHFH_01886 4.67e-190 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KPMDMHFH_01887 6.67e-282 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KPMDMHFH_01888 2.26e-308 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDPglucose--hexose-1-phosphate uridylyltransferase
KPMDMHFH_01889 4.75e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KPMDMHFH_01890 1.7e-200 yvgN - - C - - - reductase
KPMDMHFH_01891 9.58e-147 - - - S - - - Protein of unknown function (DUF1275)
KPMDMHFH_01892 2.49e-140 yodC - - C - - - nitroreductase
KPMDMHFH_01893 7.33e-289 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPMDMHFH_01894 2.21e-195 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
KPMDMHFH_01895 8.17e-98 ywnA_2 - - K - - - Transcriptional regulator
KPMDMHFH_01896 7.42e-193 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
KPMDMHFH_01897 1.16e-129 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
KPMDMHFH_01898 1e-217 ydhF - - S - - - Aldo keto reductase
KPMDMHFH_01899 2.67e-125 - - - K - - - WHG domain
KPMDMHFH_01900 5.24e-159 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_01901 3.43e-260 - - - P ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KPMDMHFH_01904 1.16e-56 - - - S - - - Sugar efflux transporter for intercellular exchange
KPMDMHFH_01905 5.84e-110 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
KPMDMHFH_01906 3.92e-223 - 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen decarboxylase (URO-D)
KPMDMHFH_01907 1.17e-211 - - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KPMDMHFH_01908 9.57e-148 - - - P ko:K16958 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
KPMDMHFH_01909 9.58e-147 - - - P ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
KPMDMHFH_01910 1.33e-175 tcyC2 - - E ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
KPMDMHFH_01912 1.03e-61 - - - S - - - dextransucrase activity
KPMDMHFH_01913 0.0 - - - S - - - dextransucrase activity
KPMDMHFH_01914 7.38e-284 yfnA - - E ko:K03294 - ko00000 amino acid
KPMDMHFH_01915 5.94e-67 - - - P - - - Protein conserved in bacteria
KPMDMHFH_01916 2.65e-265 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
KPMDMHFH_01917 3.6e-30 - - - S - - - CsbD-like
KPMDMHFH_01918 2.11e-132 - - - S - - - Protein of unknown function (DUF421)
KPMDMHFH_01919 1.7e-86 - - - S - - - Protein of unknown function (DUF3290)
KPMDMHFH_01920 1.44e-229 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KPMDMHFH_01921 2.37e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KPMDMHFH_01922 1.43e-194 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
KPMDMHFH_01923 2.03e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
KPMDMHFH_01924 8.37e-296 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPMDMHFH_01925 1.1e-13 - - - S - - - Protein of unknown function (DUF1146)
KPMDMHFH_01926 7.06e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KPMDMHFH_01927 7.16e-166 - - - G - - - Domain of unknown function (DUF4832)
KPMDMHFH_01928 2.28e-108 - - - S - - - membrane
KPMDMHFH_01929 3.46e-122 - - - P - - - VTC domain
KPMDMHFH_01930 5.95e-280 - - - M ko:K06330 - ko00000 CotH kinase protein
KPMDMHFH_01931 2.44e-239 - - - M ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
KPMDMHFH_01932 0.0 - 2.4.1.52 GT4 M ko:K00712,ko:K21011 ko02025,map02025 ko00000,ko00001,ko01000,ko01003 Domain of unknown function (DUF3492)
KPMDMHFH_01933 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
KPMDMHFH_01934 1.38e-184 - - - - - - - -
KPMDMHFH_01935 0.0 - 5.1.3.2 - GM ko:K01784,ko:K21009 ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025 ko00000,ko00001,ko00002,ko01000 Psort location CytoplasmicMembrane, score
KPMDMHFH_01936 1.8e-270 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPMDMHFH_01937 2.19e-219 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KPMDMHFH_01938 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPMDMHFH_01939 3.74e-115 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KPMDMHFH_01940 2.16e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPMDMHFH_01941 9.42e-28 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
KPMDMHFH_01944 2.33e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KPMDMHFH_01945 1.05e-272 eriC - - P ko:K03281 - ko00000 Chloride transporter ClC family
KPMDMHFH_01946 3.64e-55 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
KPMDMHFH_01947 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
KPMDMHFH_01948 2.45e-98 ykuP - - C ko:K03839 - ko00000 Flavodoxin
KPMDMHFH_01949 7.17e-26 XK27_08880 - - - - - - -
KPMDMHFH_01950 5.17e-161 XK27_08875 - - O - - - Zinc-dependent metalloprotease
KPMDMHFH_01951 7.21e-192 estA - CE1 S ko:K03930 - ko00000,ko01000 Esterase
KPMDMHFH_01952 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPMDMHFH_01953 2.2e-173 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_01954 1.37e-190 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KPMDMHFH_01955 3.39e-229 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
KPMDMHFH_01957 0.0 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
KPMDMHFH_01958 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KPMDMHFH_01959 1.29e-236 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KPMDMHFH_01960 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KPMDMHFH_01961 5.58e-146 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPMDMHFH_01962 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPMDMHFH_01963 1.36e-241 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KPMDMHFH_01964 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KPMDMHFH_01965 2.15e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KPMDMHFH_01966 1.68e-227 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
KPMDMHFH_01968 3.1e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KPMDMHFH_01969 3.9e-125 ypmS - - S - - - Protein conserved in bacteria
KPMDMHFH_01970 5.29e-205 XK27_03630 - - E - - - COG2755 Lysophospholipase L1 and related esterases
KPMDMHFH_01971 2.29e-189 WQ51_01275 - - S - - - DegV family
KPMDMHFH_01972 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KPMDMHFH_01973 1.26e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KPMDMHFH_01974 6.33e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KPMDMHFH_01975 2.05e-197 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KPMDMHFH_01976 2.44e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPMDMHFH_01977 1.03e-295 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPMDMHFH_01979 1.84e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPMDMHFH_01980 3.15e-163 dnaD - - - ko:K02086 - ko00000 -
KPMDMHFH_01981 6.91e-233 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KPMDMHFH_01982 5.29e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPMDMHFH_01983 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
KPMDMHFH_01984 1.47e-86 GnaT 2.5.1.16 - K ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferase
KPMDMHFH_01985 2.89e-161 - - - Q - - - Methyltransferase domain
KPMDMHFH_01986 8.29e-175 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KPMDMHFH_01987 1.22e-219 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KPMDMHFH_01988 9.37e-142 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
KPMDMHFH_01989 4.39e-305 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPMDMHFH_01990 9.57e-294 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KPMDMHFH_01991 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
KPMDMHFH_01992 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
KPMDMHFH_01993 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
KPMDMHFH_01994 4.79e-228 - - - M - - - glycosyl transferase family 2
KPMDMHFH_01995 4.53e-162 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
KPMDMHFH_01996 9.39e-183 - - - P - - - molecular chaperone
KPMDMHFH_01997 1.38e-134 XK27_05505 - - S - - - Psort location CytoplasmicMembrane, score
KPMDMHFH_01998 0.0 prtA - - O - - - Belongs to the peptidase S8 family
KPMDMHFH_01999 5.92e-102 - - - K - - - Acetyltransferase (GNAT) domain
KPMDMHFH_02000 1.82e-181 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KPMDMHFH_02001 5.16e-182 M1-956 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KPMDMHFH_02002 2.61e-236 - - - S ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_02006 1e-36 yfjR - - K - - - regulation of single-species biofilm formation
KPMDMHFH_02007 1.14e-154 - - - S - - - Protein of unknown function DUF262
KPMDMHFH_02008 1.85e-257 - - - S - - - Protein of unknown function DUF262
KPMDMHFH_02009 1.99e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPMDMHFH_02010 1.77e-240 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KPMDMHFH_02011 2.78e-168 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KPMDMHFH_02012 4.17e-203 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_02015 1.69e-197 yocS - - S ko:K03453 - ko00000 Transporter
KPMDMHFH_02016 3.43e-89 - - - F - - - cytidine deaminase activity
KPMDMHFH_02017 5.18e-148 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transporter
KPMDMHFH_02018 2.7e-199 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
KPMDMHFH_02021 1.17e-120 XK27_05000 - - S ko:K06940 - ko00000 metal cluster binding
KPMDMHFH_02022 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
KPMDMHFH_02023 7.36e-172 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KPMDMHFH_02024 3.27e-209 - - - T - - - Histidine kinase
KPMDMHFH_02025 3.69e-159 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPMDMHFH_02026 7.25e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KPMDMHFH_02027 4.89e-283 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
KPMDMHFH_02028 0.0 - - - V ko:K06148 - ko00000,ko02000 (ABC) transporter
KPMDMHFH_02029 1.23e-187 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KPMDMHFH_02030 4.67e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
KPMDMHFH_02032 4.3e-228 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)