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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NCOHLEED_00001	2.48e-244	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NCOHLEED_00002	1.97e-137	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NCOHLEED_00003	0.0	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NCOHLEED_00004	5.2e-253	-	-	-	S	-	-	-	COG NOG26673 non supervised orthologous group
NCOHLEED_00005	4.06e-192	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family
NCOHLEED_00006	0.0	yhgF	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain
NCOHLEED_00007	2.06e-160	-	-	-	-	-	-	-	-
NCOHLEED_00008	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_00009	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NCOHLEED_00010	2.29e-71	-	-	-	-	-	-	-	-
NCOHLEED_00011	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
NCOHLEED_00012	3.21e-211	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
NCOHLEED_00013	1.57e-187	crnA	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
NCOHLEED_00014	9.06e-102	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00015	8.73e-284	-	-	-	S	-	-	-	COG NOG33609 non supervised orthologous group
NCOHLEED_00016	4.24e-310	-	-	-	-	-	-	-	-
NCOHLEED_00017	3.17e-174	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
NCOHLEED_00018	1.27e-274	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NCOHLEED_00019	7.11e-177	-	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyltransferase 26 family
NCOHLEED_00020	6.06e-276	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
NCOHLEED_00021	2.59e-280	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00022	4.05e-269	-	-	-	M	-	-	-	Glycosyltransferase Family 4
NCOHLEED_00023	1.73e-274	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_00024	1.73e-247	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCOHLEED_00025	1.35e-197	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyltransferase K00754
NCOHLEED_00026	1.31e-122	-	-	-	E	-	-	-	Bacterial transferase hexapeptide (six repeats)
NCOHLEED_00027	1.19e-62	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00028	7.16e-232	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00029	1.04e-208	-	-	-	-	-	-	-	-
NCOHLEED_00030	9.81e-281	wbpP	5.1.3.2, 5.1.3.7	-	M	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
NCOHLEED_00031	2.93e-234	-	-	-	G	-	-	-	Acyltransferase family
NCOHLEED_00032	2.02e-144	-	-	-	E	-	-	-	Bacterial transferase hexapeptide (six repeats)
NCOHLEED_00033	6.85e-236	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00034	2.27e-249	-	-	-	-	-	-	-	-
NCOHLEED_00035	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00036	7.35e-290	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00037	0.0	ugd	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NCOHLEED_00039	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
NCOHLEED_00040	7.67e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
NCOHLEED_00041	4.8e-116	-	-	-	L	-	-	-	DNA-binding protein
NCOHLEED_00042	2.35e-08	-	-	-	-	-	-	-	-
NCOHLEED_00043	1.03e-109	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00044	5.04e-127	-	-	-	K	-	-	-	Transcription termination antitermination factor NusG
NCOHLEED_00045	0.0	ptk_3	-	-	DM	-	-	-	Chain length determinant protein
NCOHLEED_00046	3.39e-185	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
NCOHLEED_00047	0.0	wcaJ_2	2.7.8.6	-	M	ko:K00996,ko:K03606	ko05111,map05111	ko00000,ko00001,ko01000,ko01005	Psort location CytoplasmicMembrane, score
NCOHLEED_00048	1.03e-161	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_00049	9.22e-135	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00050	2.49e-312	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00054	1.53e-96	-	-	-	-	-	-	-	-
NCOHLEED_00055	1.06e-148	-	-	-	S	ko:K03975	-	ko00000	Psort location CytoplasmicMembrane, score
NCOHLEED_00056	9.07e-150	-	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
NCOHLEED_00057	4.14e-232	pitA	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
NCOHLEED_00058	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00060	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
NCOHLEED_00061	9.52e-174	-	-	-	S	-	-	-	COG NOG22668 non supervised orthologous group
NCOHLEED_00062	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
NCOHLEED_00063	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location CytoplasmicMembrane, score
NCOHLEED_00064	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00065	3.57e-271	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
NCOHLEED_00066	6.2e-265	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NCOHLEED_00067	6.08e-257	sstT	-	-	U	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NCOHLEED_00068	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NCOHLEED_00069	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NCOHLEED_00070	2.42e-179	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase
NCOHLEED_00071	2.35e-243	yhiM	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00072	7.24e-160	pdxH	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
NCOHLEED_00073	1.68e-156	-	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NCOHLEED_00074	6.58e-161	-	-	-	K	-	-	-	COG3279 Response regulator of the LytR AlgR family
NCOHLEED_00075	2.4e-256	cheA	-	-	T	-	-	-	two-component sensor histidine kinase
NCOHLEED_00076	3.17e-280	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NCOHLEED_00077	2.11e-169	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NCOHLEED_00078	1.04e-236	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_00079	2.61e-314	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	type I secretion outer membrane protein, TolC family
NCOHLEED_00080	4.86e-45	-	-	-	S	-	-	-	COG NOG17489 non supervised orthologous group
NCOHLEED_00081	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1271 Cytochrome bd-type quinol oxidase, subunit 1
NCOHLEED_00082	2.7e-278	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase subunit 2
NCOHLEED_00083	5.22e-163	mtgA	2.4.1.129	GT51	M	ko:K03814	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NCOHLEED_00084	1.14e-120	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
NCOHLEED_00085	1.41e-315	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00086	0.0	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location Periplasmic, score 9.44
NCOHLEED_00087	1.6e-176	ydcV	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
NCOHLEED_00088	1.96e-183	-	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00089	0.0	potA	3.6.3.29, 3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K02017,ko:K10112,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NCOHLEED_00090	7.68e-177	ydfG	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NCOHLEED_00091	0.0	aglC	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	COG3345 Alpha-galactosidase
NCOHLEED_00093	0.0	-	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
NCOHLEED_00094	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
NCOHLEED_00095	0.0	-	-	-	S	-	-	-	Phosphatase
NCOHLEED_00096	0.0	-	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	COG1864 DNA RNA endonuclease G, NUC1
NCOHLEED_00097	0.0	dbpA	3.6.4.13	-	L	ko:K05591	-	ko00000,ko01000,ko03009	ATP-independent RNA helicase DbpA
NCOHLEED_00098	2.5e-258	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NCOHLEED_00099	2.97e-214	serA	1.1.1.399, 1.1.1.95	-	C	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCOHLEED_00100	3.48e-309	-	-	-	S	-	-	-	Conserved protein
NCOHLEED_00101	4.79e-140	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00102	3.22e-94	mip	5.2.1.8	-	O	ko:K01802	-	ko00000,ko01000	COG COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
NCOHLEED_00103	5.25e-37	-	-	-	-	-	-	-	-
NCOHLEED_00104	3.54e-311	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00105	1.36e-267	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NCOHLEED_00106	5.95e-133	yigZ	-	-	S	-	-	-	YigZ family
NCOHLEED_00107	2.11e-271	hpaIIR	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	COG NOG26934 non supervised orthologous group
NCOHLEED_00108	2.38e-138	-	-	-	C	-	-	-	Nitroreductase family
NCOHLEED_00109	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score 9.52
NCOHLEED_00110	1.03e-09	-	-	-	-	-	-	-	-
NCOHLEED_00111	3.1e-80	-	-	-	K	-	-	-	Bacterial regulatory proteins, gntR family
NCOHLEED_00112	5.24e-187	-	-	-	-	-	-	-	-
NCOHLEED_00113	1.38e-187	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NCOHLEED_00114	8.22e-164	hly-III	-	-	S	ko:K11068	-	ko00000,ko02042	membrane protein, hemolysin III homolog
NCOHLEED_00115	0.0	gcvP	1.4.4.2	-	E	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NCOHLEED_00116	1.07e-160	-	-	-	P	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00117	8.81e-148	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NCOHLEED_00118	1.78e-206	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
NCOHLEED_00119	0.0	-	-	-	P	-	-	-	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
NCOHLEED_00120	7.55e-59	-	-	-	P	ko:K08364	-	ko00000,ko02000	Heavy metal-associated domain protein
NCOHLEED_00121	0.0	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00122	1.3e-198	-	-	-	K	-	-	-	COG2207 AraC-type DNA-binding domain-containing
NCOHLEED_00123	0.0	-	-	-	P	-	-	-	TonB dependent receptor
NCOHLEED_00124	6.53e-154	lipB	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
NCOHLEED_00125	4.41e-139	acpH	-	-	S	-	-	-	Acyl carrier protein phosphodiesterase
NCOHLEED_00126	4.19e-183	-	-	-	L	-	-	-	COG NOG19076 non supervised orthologous group
NCOHLEED_00127	3.06e-79	-	-	-	S	-	-	-	WYL_2, Sm-like SH3 beta-barrel fold
NCOHLEED_00129	1.16e-122	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00130	3.93e-111	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00131	8.55e-249	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00132	1.09e-250	vioA	2.6.1.33	-	E	ko:K20429	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
NCOHLEED_00133	1.62e-184	-	-	-	O	-	-	-	peptidase U32
NCOHLEED_00134	6.88e-157	-	-	-	G	-	-	-	Citrate lyase beta subunit
NCOHLEED_00135	1.27e-106	-	-	-	C	-	-	-	aldo keto reductase
NCOHLEED_00136	3.34e-129	-	-	-	S	-	-	-	PFAM MmgE PrpD family protein
NCOHLEED_00137	1.28e-125	aepY	4.1.1.82	-	EH	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NCOHLEED_00138	2.05e-126	-	-	-	F	ko:K16181	ko00300,ko01120,map00300,map01120	ko00000,ko00001	phosphoribosylamine-glycine ligase activity
NCOHLEED_00139	5.21e-73	-	4.2.1.2	-	C	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
NCOHLEED_00141	1.37e-129	-	4.2.1.2	-	C	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	tartrate metabolic process
NCOHLEED_00142	2.25e-71	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family
NCOHLEED_00143	2.22e-41	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NCOHLEED_00144	7.12e-05	wzy	-	-	S	ko:K19419	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
NCOHLEED_00145	1.12e-86	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_00146	1.67e-232	-	5.1.3.2	-	M	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Polysaccharide biosynthesis protein C-terminal
NCOHLEED_00147	7.45e-164	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NCOHLEED_00148	7.59e-249	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
NCOHLEED_00149	7.37e-174	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_00150	2.4e-106	wcgX	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00152	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00153	4.62e-182	-	-	-	I	-	-	-	Protein of unknown function (DUF1460)
NCOHLEED_00154	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
NCOHLEED_00155	2.47e-221	-	-	-	I	-	-	-	pectin acetylesterase
NCOHLEED_00156	0.0	-	-	-	S	-	-	-	oligopeptide transporter, OPT family
NCOHLEED_00157	8.25e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
NCOHLEED_00158	6.06e-163	-	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG2243 Precorrin-2 methylase
NCOHLEED_00159	1.94e-193	-	-	-	K	-	-	-	COG COG2207 AraC-type DNA-binding domain-containing proteins
NCOHLEED_00160	4.38e-134	ykgB	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_00161	0.0	merA	-	-	C	ko:K21739	-	ko00000	COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NCOHLEED_00162	6.35e-276	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NCOHLEED_00163	1.69e-222	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NCOHLEED_00164	5.12e-243	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NCOHLEED_00165	0.0	norM	-	-	V	-	-	-	MATE efflux family protein
NCOHLEED_00166	3.57e-261	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NCOHLEED_00167	7.15e-156	-	-	-	M	-	-	-	COG NOG19089 non supervised orthologous group
NCOHLEED_00168	0.0	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NCOHLEED_00169	0.0	cobM	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG2875 Precorrin-4 methylase
NCOHLEED_00170	6.3e-306	cbiE	2.1.1.132	-	H	ko:K00595	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE
NCOHLEED_00171	0.0	cobJ	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG1010 Precorrin-3B methylase
NCOHLEED_00172	1.54e-217	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
NCOHLEED_00173	1.18e-188	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	CbiX
NCOHLEED_00174	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
NCOHLEED_00175	6.09e-70	-	-	-	S	-	-	-	Conserved protein
NCOHLEED_00176	3.27e-127	-	-	-	U	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_00177	2.56e-123	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00178	0.0	-	6.6.1.2	-	H	ko:K02230	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG1429 Cobalamin biosynthesis protein CobN and related
NCOHLEED_00179	0.0	-	-	-	S	-	-	-	domain protein
NCOHLEED_00180	8.02e-228	-	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG4822 Cobalamin biosynthesis protein CbiK Co2 chelatase
NCOHLEED_00181	1.4e-314	-	-	-	-	-	-	-	-
NCOHLEED_00182	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00183	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
NCOHLEED_00184	1.84e-116	-	6.4.1.1	-	I	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Biotin-requiring enzyme
NCOHLEED_00185	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
NCOHLEED_00186	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00187	2.91e-181	hddC	-	-	JM	-	-	-	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
NCOHLEED_00188	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00189	0.0	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
NCOHLEED_00190	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00191	6.22e-34	-	-	-	-	-	-	-	-
NCOHLEED_00192	1.59e-141	-	-	-	S	-	-	-	Zeta toxin
NCOHLEED_00193	1e-131	-	-	-	S	-	-	-	ATP cob(I)alamin adenosyltransferase
NCOHLEED_00194	6.08e-297	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NCOHLEED_00195	2.06e-33	-	-	-	-	-	-	-	-
NCOHLEED_00196	1.53e-154	-	-	-	L	-	-	-	Phage integrase SAM-like domain
NCOHLEED_00198	9.07e-94	-	-	-	S	-	-	-	dihydrofolate reductase family protein K00287
NCOHLEED_00199	2.44e-36	-	-	-	-	-	-	-	-
NCOHLEED_00200	2.97e-76	-	-	-	L	-	-	-	RNA-DNA hybrid ribonuclease activity
NCOHLEED_00201	3.63e-105	-	-	-	-	-	-	-	-
NCOHLEED_00202	1.08e-122	-	-	-	-	-	-	-	-
NCOHLEED_00203	1.36e-51	-	-	-	S	-	-	-	MutS domain I
NCOHLEED_00204	7.45e-36	-	-	-	-	-	-	-	-
NCOHLEED_00205	4.26e-46	-	-	-	-	-	-	-	-
NCOHLEED_00206	9e-115	-	-	-	-	-	-	-	-
NCOHLEED_00207	4.94e-52	-	-	-	-	-	-	-	-
NCOHLEED_00212	7.8e-58	-	-	-	-	-	-	-	-
NCOHLEED_00213	1.01e-64	-	-	-	-	-	-	-	-
NCOHLEED_00214	2.07e-64	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00216	5.8e-16	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00218	1.21e-43	-	-	-	-	-	-	-	-
NCOHLEED_00219	3.45e-31	-	-	-	-	-	-	-	-
NCOHLEED_00220	7.47e-112	-	-	-	-	-	-	-	-
NCOHLEED_00221	1.53e-84	-	-	-	-	-	-	-	-
NCOHLEED_00222	7.18e-59	-	-	-	-	-	-	-	-
NCOHLEED_00223	1.35e-78	-	-	-	-	-	-	-	-
NCOHLEED_00224	3.67e-153	-	-	-	-	-	-	-	-
NCOHLEED_00225	1.36e-186	-	-	-	S	-	-	-	DpnD/PcfM-like protein
NCOHLEED_00226	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00227	1.94e-114	-	-	-	-	-	-	-	-
NCOHLEED_00228	4.03e-98	-	-	-	-	-	-	-	-
NCOHLEED_00229	3.41e-106	-	-	-	L	-	-	-	Phage integrase family
NCOHLEED_00230	1.7e-205	-	-	-	-	-	-	-	-
NCOHLEED_00231	1.18e-138	-	-	-	-	-	-	-	-
NCOHLEED_00232	1.83e-190	-	-	-	-	-	-	-	-
NCOHLEED_00233	8.52e-41	-	-	-	-	-	-	-	-
NCOHLEED_00234	1.74e-113	-	-	-	-	-	-	-	-
NCOHLEED_00235	3.34e-199	-	-	-	-	-	-	-	-
NCOHLEED_00238	2.25e-39	-	-	-	-	-	-	-	-
NCOHLEED_00240	9.32e-128	-	-	-	-	-	-	-	-
NCOHLEED_00241	2.06e-31	-	-	-	-	-	-	-	-
NCOHLEED_00242	1.65e-198	-	-	-	-	-	-	-	-
NCOHLEED_00243	4.53e-126	-	-	-	-	-	-	-	-
NCOHLEED_00247	2.9e-29	-	-	-	-	-	-	-	-
NCOHLEED_00248	2.14e-32	-	-	-	-	-	-	-	-
NCOHLEED_00249	2.91e-256	-	-	-	-	-	-	-	-
NCOHLEED_00250	7.41e-117	-	-	-	-	-	-	-	-
NCOHLEED_00252	1.03e-250	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
NCOHLEED_00255	1.36e-46	-	-	-	-	-	-	-	-
NCOHLEED_00257	4.04e-66	-	-	-	-	-	-	-	-
NCOHLEED_00258	1.78e-90	-	-	-	-	-	-	-	-
NCOHLEED_00259	8.53e-59	-	-	-	S	-	-	-	Domain of unknown function (DUF3846)
NCOHLEED_00260	3.06e-108	-	-	-	-	-	-	-	-
NCOHLEED_00261	2.47e-160	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00262	4.98e-222	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00263	4.99e-107	-	-	-	-	-	-	-	-
NCOHLEED_00264	1.02e-41	-	-	-	-	-	-	-	-
NCOHLEED_00265	8.99e-31	-	-	-	-	-	-	-	-
NCOHLEED_00267	5.94e-79	-	-	-	-	-	-	-	-
NCOHLEED_00270	3.06e-127	-	-	-	-	-	-	-	-
NCOHLEED_00271	1.73e-72	-	-	-	-	-	-	-	-
NCOHLEED_00272	2.07e-32	-	-	-	-	-	-	-	-
NCOHLEED_00273	1.59e-84	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00274	1.03e-246	-	-	-	S	-	-	-	Phage antirepressor protein KilAC domain
NCOHLEED_00275	2.1e-71	-	-	-	-	-	-	-	-
NCOHLEED_00276	6.9e-92	-	-	-	-	-	-	-	-
NCOHLEED_00277	1.07e-286	-	-	-	S	-	-	-	Protein of unknown function (DUF935)
NCOHLEED_00278	1.08e-117	-	-	-	S	-	-	-	Phage Mu protein F like protein
NCOHLEED_00279	9.73e-100	-	-	-	-	-	-	-	-
NCOHLEED_00280	3.71e-141	-	-	-	-	-	-	-	-
NCOHLEED_00281	9.88e-255	-	-	-	OU	-	-	-	Clp protease
NCOHLEED_00282	6.28e-249	-	-	-	-	-	-	-	-
NCOHLEED_00283	1.07e-37	-	-	-	-	-	-	-	-
NCOHLEED_00284	1.24e-313	-	-	-	-	-	-	-	-
NCOHLEED_00285	4.19e-101	-	-	-	-	-	-	-	-
NCOHLEED_00286	2.56e-110	-	-	-	L	-	-	-	DNA N-6-adenine-methyltransferase (Dam)
NCOHLEED_00287	4.55e-165	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NCOHLEED_00288	4.87e-151	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00289	2.95e-158	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00290	5.61e-69	-	-	-	-	-	-	-	-
NCOHLEED_00291	0.0	-	-	-	S	-	-	-	Phage-related minor tail protein
NCOHLEED_00292	4.71e-216	-	-	-	-	-	-	-	-
NCOHLEED_00293	7.33e-306	-	-	-	S	-	-	-	Late control gene D protein
NCOHLEED_00295	1.56e-202	-	-	-	S	-	-	-	Protein of unknown function DUF262
NCOHLEED_00296	2.4e-183	-	-	-	-	-	-	-	-
NCOHLEED_00297	9.06e-313	-	-	-	-	-	-	-	-
NCOHLEED_00298	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00299	1.48e-275	-	-	-	-	-	-	-	-
NCOHLEED_00300	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00301	1.41e-09	-	-	-	-	-	-	-	-
NCOHLEED_00302	1.51e-53	-	-	-	-	-	-	-	-
NCOHLEED_00303	7.1e-104	-	-	-	-	-	-	-	-
NCOHLEED_00304	2.79e-147	-	-	-	-	-	-	-	-
NCOHLEED_00305	2.65e-192	-	-	-	-	-	-	-	-
NCOHLEED_00306	5.33e-122	-	-	-	-	-	-	-	-
NCOHLEED_00307	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00308	2.14e-91	-	-	-	-	-	-	-	-
NCOHLEED_00309	1.06e-264	-	-	-	-	-	-	-	-
NCOHLEED_00310	1.65e-215	-	-	-	-	ko:K03547	-	ko00000,ko03400	-
NCOHLEED_00311	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00312	5.14e-100	-	-	-	L	-	-	-	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NCOHLEED_00313	2.97e-125	-	-	-	K	-	-	-	DNA-templated transcription, initiation
NCOHLEED_00314	5.77e-123	-	-	-	-	-	-	-	-
NCOHLEED_00315	5.65e-275	-	-	-	S	-	-	-	DnaB-like helicase C terminal domain
NCOHLEED_00317	8.83e-39	-	-	-	K	ko:K07727	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00318	2.49e-47	-	-	-	-	-	-	-	-
NCOHLEED_00319	9.63e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
NCOHLEED_00320	3.41e-144	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_00321	4.37e-141	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_00322	2.11e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_00323	9e-183	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family
NCOHLEED_00324	1.32e-111	-	-	-	S	-	-	-	Family of unknown function (DUF3836)
NCOHLEED_00326	3.65e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin biosynthesis protein
NCOHLEED_00327	5.31e-149	yihX	3.1.3.10	-	S	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00328	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00329	8.1e-18	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
NCOHLEED_00330	3.81e-36	rubR	-	-	C	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00331	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00332	0.0	udk2	2.7.1.48	-	FJ	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphoribulokinase Uridine kinase family
NCOHLEED_00333	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_00334	4.67e-95	-	-	-	S	-	-	-	Tetratricopeptide repeat
NCOHLEED_00335	2.61e-39	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
NCOHLEED_00336	5.2e-33	-	-	-	-	-	-	-	-
NCOHLEED_00337	1.31e-299	-	-	-	CO	-	-	-	Thioredoxin
NCOHLEED_00338	2.36e-217	-	-	-	O	-	-	-	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NCOHLEED_00339	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NCOHLEED_00340	3.54e-244	-	-	-	M	ko:K02022	-	ko00000	HlyD family secretion protein
NCOHLEED_00342	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
NCOHLEED_00343	0.0	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog
NCOHLEED_00344	2.21e-148	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00345	6.1e-87	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NCOHLEED_00346	1.29e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NCOHLEED_00347	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NCOHLEED_00348	1.38e-253	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NCOHLEED_00349	3.44e-194	-	-	-	S	-	-	-	Phospholipase/Carboxylesterase
NCOHLEED_00350	0.0	-	-	-	CP	-	-	-	COG3119 Arylsulfatase A
NCOHLEED_00351	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
NCOHLEED_00352	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
NCOHLEED_00353	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	COG COG3119 Arylsulfatase A and related enzymes
NCOHLEED_00354	0.0	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
NCOHLEED_00355	1.64e-204	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
NCOHLEED_00356	0.0	-	-	-	S	-	-	-	Putative glucoamylase
NCOHLEED_00357	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_00358	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00359	1.2e-286	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
NCOHLEED_00360	2.8e-303	-	-	-	S	-	-	-	COG NOG11699 non supervised orthologous group
NCOHLEED_00361	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
NCOHLEED_00362	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NCOHLEED_00363	0.0	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
NCOHLEED_00364	0.0	-	-	-	KT	-	-	-	COG NOG11230 non supervised orthologous group
NCOHLEED_00366	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00367	0.0	prc	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NCOHLEED_00368	3.36e-228	-	-	-	G	-	-	-	Kinase, PfkB family
NCOHLEED_00371	2.74e-142	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NCOHLEED_00372	1.02e-169	comF	2.4.2.14	-	S	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	ComF family
NCOHLEED_00373	6.68e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_00374	1.1e-108	-	-	-	O	-	-	-	Heat shock protein
NCOHLEED_00375	2.46e-121	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00377	3.81e-109	-	-	-	S	-	-	-	CHAT domain
NCOHLEED_00378	0.0	hcpC	-	-	KLT	ko:K07126	-	ko00000	COG0790 FOG TPR repeat, SEL1 subfamily
NCOHLEED_00379	7.34e-99	-	-	-	L	-	-	-	DNA-binding protein
NCOHLEED_00380	2.67e-121	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III epsilon subunit and related 3'-5'
NCOHLEED_00381	7.75e-131	-	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00382	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_00383	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00384	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NCOHLEED_00385	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Psort location Cytoplasmic, score
NCOHLEED_00386	1.7e-50	hupB	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NCOHLEED_00387	2.06e-161	-	3.4.21.105	-	S	ko:K09650	-	ko00000,ko01000,ko01002,ko03029	Psort location CytoplasmicMembrane, score
NCOHLEED_00388	9.49e-206	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00389	1.41e-265	-	-	-	L	-	-	-	Endonuclease Exonuclease phosphatase family
NCOHLEED_00390	0.0	dcp	3.4.15.5	-	E	ko:K01284	-	ko00000,ko01000,ko01002	Peptidase family M3
NCOHLEED_00391	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NCOHLEED_00393	0.0	porA	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid acceptor oxidoreductase, alpha subunit
NCOHLEED_00394	2.03e-251	oorB	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
NCOHLEED_00395	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00396	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
NCOHLEED_00397	0.0	-	-	-	Q	-	-	-	AMP-binding enzyme
NCOHLEED_00398	6.73e-51	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
NCOHLEED_00399	0.0	-	-	-	M	-	-	-	MBOAT, membrane-bound O-acyltransferase family
NCOHLEED_00400	9.61e-271	-	-	-	-	-	-	-	-
NCOHLEED_00401	4.64e-155	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	uracil phosphoribosyltransferase
NCOHLEED_00402	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NCOHLEED_00403	8.97e-141	-	-	-	C	-	-	-	Nitroreductase family
NCOHLEED_00404	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NCOHLEED_00405	4.82e-55	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NCOHLEED_00406	2.22e-205	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
NCOHLEED_00407	4.1e-111	-	-	-	S	-	-	-	COG NOG30135 non supervised orthologous group
NCOHLEED_00408	0.0	-	-	-	H	-	-	-	Outer membrane protein beta-barrel family
NCOHLEED_00409	5.34e-128	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00410	0.0	-	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	Psort location Cytoplasmic, score 9.97
NCOHLEED_00411	1.53e-117	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NCOHLEED_00412	6.15e-171	mtnN	3.2.2.9	-	F	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NCOHLEED_00413	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00414	7.85e-69	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NCOHLEED_00415	6.78e-289	lolE	-	-	M	ko:K09808,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4591 ABC-type transport system, involved in lipoprotein release, permease component
NCOHLEED_00416	8.13e-150	mdmC	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_00417	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
NCOHLEED_00418	6.15e-95	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
NCOHLEED_00419	3.82e-227	xerC	-	-	D	ko:K04763	-	ko00000,ko03036	Tyrosine recombinase XerC
NCOHLEED_00420	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_00421	1.25e-243	-	-	-	CO	-	-	-	AhpC TSA family
NCOHLEED_00422	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI
NCOHLEED_00423	0.0	-	-	-	C	ko:K09181	-	ko00000	CoA binding domain protein
NCOHLEED_00424	1.03e-218	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00425	7.8e-238	-	-	-	T	-	-	-	Histidine kinase
NCOHLEED_00426	2.05e-178	-	-	-	K	-	-	-	LytTr DNA-binding domain protein
NCOHLEED_00427	7.41e-222	-	-	-	-	-	-	-	-
NCOHLEED_00428	7.63e-106	-	-	-	S	-	-	-	COG NOG19145 non supervised orthologous group
NCOHLEED_00429	2.59e-160	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
NCOHLEED_00430	1.48e-246	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_00431	9.68e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NCOHLEED_00432	6.16e-48	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NCOHLEED_00433	3.7e-149	spk1	2.7.11.1, 6.3.2.4	-	S	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01001,ko01011	PASTA domain protein
NCOHLEED_00434	1.58e-266	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NCOHLEED_00435	3.86e-236	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NCOHLEED_00436	1.45e-279	-	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00437	1.34e-159	-	-	-	S	-	-	-	COG NOG31798 non supervised orthologous group
NCOHLEED_00438	1.86e-87	glpE	-	-	P	-	-	-	Rhodanese-like protein
NCOHLEED_00439	7.48e-234	argF	2.1.3.11, 2.1.3.9	-	E	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NCOHLEED_00440	2.32e-298	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NCOHLEED_00441	3.42e-258	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NCOHLEED_00442	1.38e-45	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00443	4.04e-203	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NCOHLEED_00444	8.68e-84	-	-	-	M	ko:K06142	-	ko00000	Membrane
NCOHLEED_00445	2.49e-105	ompH	-	-	M	ko:K06142	-	ko00000	membrane
NCOHLEED_00446	0.0	yaeT	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Outer membrane protein assembly complex, YaeT protein
NCOHLEED_00447	3.99e-179	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NCOHLEED_00448	0.0	-	-	-	G	-	-	-	COG NOG27066 non supervised orthologous group
NCOHLEED_00449	9.73e-254	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NCOHLEED_00450	8.44e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NCOHLEED_00451	3.14e-109	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
NCOHLEED_00452	5.07e-150	pyrE	2.4.2.10, 4.1.1.23	-	F	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NCOHLEED_00453	9.16e-91	-	-	-	S	-	-	-	Polyketide cyclase
NCOHLEED_00454	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score
NCOHLEED_00457	0.0	-	-	-	NU	-	-	-	Lipid A 3-O-deacylase (PagL)
NCOHLEED_00458	0.0	acsA	6.2.1.1, 6.2.1.32	-	I	ko:K01895,ko:K08295	ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score
NCOHLEED_00459	8.98e-128	-	-	-	K	-	-	-	Cupin domain protein
NCOHLEED_00460	2.37e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NCOHLEED_00461	7.39e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NCOHLEED_00462	5.09e-239	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NCOHLEED_00463	1.4e-44	-	-	-	KT	-	-	-	PspC domain protein
NCOHLEED_00464	4.11e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate synthase
NCOHLEED_00465	3.81e-134	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00466	8.01e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NCOHLEED_00470	2.26e-243	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the LDH MDH superfamily
NCOHLEED_00471	8.44e-200	yitL	-	-	S	ko:K00243	-	ko00000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00472	3.56e-168	-	-	-	J	-	-	-	Domain of unknown function (DUF4476)
NCOHLEED_00473	7.71e-166	-	-	-	S	-	-	-	COG NOG36047 non supervised orthologous group
NCOHLEED_00474	8.28e-308	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	Psort location OuterMembrane, score 10.00
NCOHLEED_00475	1.16e-244	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_00476	2.21e-295	macB_3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NCOHLEED_00477	2.83e-301	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NCOHLEED_00478	1.89e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NCOHLEED_00479	5.49e-236	glk	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.26
NCOHLEED_00480	4e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NCOHLEED_00481	1.74e-177	ushA	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
NCOHLEED_00482	2.67e-221	-	3.1.3.5, 3.6.1.45	-	F	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Ser Thr phosphatase family protein
NCOHLEED_00483	0.0	nagA	-	-	M	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding
NCOHLEED_00484	0.0	nagA	-	-	G	-	-	-	b-glycosidase, glycoside hydrolase family 3 protein
NCOHLEED_00485	2.63e-155	-	-	-	M	-	-	-	COG NOG27406 non supervised orthologous group
NCOHLEED_00486	4.03e-156	-	-	-	S	-	-	-	COG NOG26965 non supervised orthologous group
NCOHLEED_00487	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
NCOHLEED_00488	2.18e-246	gpr	-	-	C	ko:K19265	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
NCOHLEED_00489	0.0	cepA	2.4.1.20	GT36	G	ko:K00702	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Putative carbohydrate binding domain
NCOHLEED_00490	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	hydrolase family 2, sugar binding
NCOHLEED_00492	3.78e-217	-	-	-	K	-	-	-	Transcriptional regulator, AraC family
NCOHLEED_00493	0.0	-	-	-	Q	-	-	-	COG3458 Acetyl esterase (deacetylase)
NCOHLEED_00494	0.0	-	3.2.1.78	-	G	ko:K19355	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NCOHLEED_00495	1.08e-251	eglS	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NCOHLEED_00496	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00497	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_00498	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00499	0.0	-	-	-	U	-	-	-	domain, Protein
NCOHLEED_00500	0.0	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Glycosyl hydrolase family 26
NCOHLEED_00501	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00502	0.0	-	-	-	GM	-	-	-	SusD family
NCOHLEED_00503	8.8e-211	-	-	-	-	-	-	-	-
NCOHLEED_00504	3.7e-175	-	-	-	-	-	-	-	-
NCOHLEED_00505	8.23e-154	-	-	-	L	-	-	-	Bacterial DNA-binding protein
NCOHLEED_00506	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
NCOHLEED_00507	2.48e-275	-	-	-	J	-	-	-	endoribonuclease L-PSP
NCOHLEED_00508	3.18e-140	-	-	-	S	-	-	-	Domain of unknown function (DUF4369)
NCOHLEED_00509	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00510	0.0	-	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
NCOHLEED_00511	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00512	0.0	-	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
NCOHLEED_00513	3.35e-276	-	3.2.1.78	GH26	G	ko:K01218,ko:K19355	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
NCOHLEED_00514	2.11e-295	-	2.4.1.281	-	G	ko:K16212	-	ko00000,ko01000	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NCOHLEED_00515	0.0	yicJ_1	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00516	1.5e-302	bfce	5.1.3.11	-	G	ko:K16213	-	ko00000,ko01000	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
NCOHLEED_00517	7.54e-200	-	-	-	S	-	-	-	GDSL-like Lipase/Acylhydrolase
NCOHLEED_00518	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NCOHLEED_00519	0.0	-	-	-	T	ko:K02481	-	ko00000,ko02022	acetoacetate metabolism regulatory protein AtoC
NCOHLEED_00520	4.84e-40	-	-	-	-	-	-	-	-
NCOHLEED_00521	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NCOHLEED_00522	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NCOHLEED_00523	1.32e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NCOHLEED_00524	6.35e-182	-	-	-	S	-	-	-	COG NOG26951 non supervised orthologous group
NCOHLEED_00525	5.69e-259	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Psort location Cytoplasmic, score 8.96
NCOHLEED_00526	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_00527	1.12e-209	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
NCOHLEED_00528	0.0	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00529	2.36e-247	-	-	-	V	ko:K03543	-	ko00000,ko00002,ko02000	Auxiliary transport protein, membrane fusion protein
NCOHLEED_00530	9.36e-317	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00532	8.36e-90	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00533	0.0	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
NCOHLEED_00534	3.66e-294	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NCOHLEED_00535	1.79e-286	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	COG0436 Aspartate tyrosine aromatic aminotransferase
NCOHLEED_00536	1.02e-19	-	-	-	C	-	-	-	4Fe-4S binding domain
NCOHLEED_00537	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
NCOHLEED_00538	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_00539	0.0	dnaX	2.7.7.7	-	H	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NCOHLEED_00540	1.01e-62	-	-	-	D	-	-	-	Septum formation initiator
NCOHLEED_00541	4.21e-72	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_00542	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5121)
NCOHLEED_00543	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
NCOHLEED_00544	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_00545	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00546	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00547	0.0	-	-	-	S	-	-	-	MAC/Perforin domain
NCOHLEED_00549	1e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
NCOHLEED_00550	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NCOHLEED_00551	0.0	msbA	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NCOHLEED_00552	2.76e-273	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00553	0.0	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
NCOHLEED_00554	4.37e-206	-	-	-	G	-	-	-	COG NOG16664 non supervised orthologous group
NCOHLEED_00555	1.27e-221	-	-	-	M	-	-	-	COG COG1082 Sugar phosphate isomerases epimerases
NCOHLEED_00556	1.53e-158	rnhA	3.1.26.4	-	C	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	double-stranded RNA RNA-DNA hybrid binding protein
NCOHLEED_00557	1.86e-146	-	-	-	S	ko:K07078	-	ko00000	oxidoreductase related to nitroreductase
NCOHLEED_00558	3.43e-123	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NCOHLEED_00559	0.0	speA	4.1.1.19	-	H	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the biosynthesis of agmatine from arginine
NCOHLEED_00560	2.79e-178	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NCOHLEED_00561	1.03e-112	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NCOHLEED_00562	1.27e-104	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00563	0.0	-	-	-	KT	-	-	-	response regulator
NCOHLEED_00564	5.55e-91	-	-	-	-	-	-	-	-
NCOHLEED_00565	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score 9.52
NCOHLEED_00566	7.57e-131	-	-	-	S	-	-	-	COG NOG16223 non supervised orthologous group
NCOHLEED_00567	2.05e-155	-	-	-	S	ko:K07043	-	ko00000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00568	6.04e-85	-	-	-	S	-	-	-	COG NOG29451 non supervised orthologous group
NCOHLEED_00569	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
NCOHLEED_00570	0.0	-	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
NCOHLEED_00571	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00572	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_00573	0.0	-	-	-	G	-	-	-	Fibronectin type III-like domain
NCOHLEED_00574	2.67e-220	xynZ	-	-	S	-	-	-	Esterase
NCOHLEED_00575	1.26e-297	-	-	-	P	ko:K07214	-	ko00000	Putative esterase
NCOHLEED_00576	7.13e-298	-	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase
NCOHLEED_00577	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
NCOHLEED_00578	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycoside hydrolase, family 3
NCOHLEED_00579	7.46e-106	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NCOHLEED_00580	3.96e-293	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NCOHLEED_00581	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NCOHLEED_00582	2.84e-55	cvpA	-	-	S	ko:K03558	-	ko00000	Psort location CytoplasmicMembrane, score
NCOHLEED_00583	0.0	sufB	-	-	O	ko:K09014	-	ko00000	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
NCOHLEED_00584	1.05e-175	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component
NCOHLEED_00585	0.0	sufD	-	-	O	ko:K09015	-	ko00000	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
NCOHLEED_00586	1.31e-307	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family
NCOHLEED_00587	1.25e-67	-	-	-	S	-	-	-	Belongs to the UPF0145 family
NCOHLEED_00588	0.0	-	-	-	S	-	-	-	COG NOG28036 non supervised orthologous group
NCOHLEED_00589	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
NCOHLEED_00590	0.0	-	-	-	S	-	-	-	COG NOG26858 non supervised orthologous group
NCOHLEED_00591	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00592	6.85e-227	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
NCOHLEED_00593	1.19e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
NCOHLEED_00594	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NCOHLEED_00595	7.68e-274	-	-	-	O	-	-	-	COG NOG14454 non supervised orthologous group
NCOHLEED_00596	5.89e-98	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NCOHLEED_00597	7.99e-89	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family
NCOHLEED_00598	2.97e-269	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
NCOHLEED_00600	3.36e-206	-	-	-	K	-	-	-	Fic/DOC family
NCOHLEED_00601	0.0	-	-	-	T	-	-	-	PAS fold
NCOHLEED_00602	8.04e-230	-	-	-	S	-	-	-	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
NCOHLEED_00603	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00604	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_00605	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00606	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00607	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NCOHLEED_00608	0.0	celA	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NCOHLEED_00609	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_00610	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
NCOHLEED_00611	0.0	bga	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NCOHLEED_00612	0.0	bglB_3	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
NCOHLEED_00613	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
NCOHLEED_00614	0.0	-	-	-	V	-	-	-	beta-lactamase
NCOHLEED_00615	7.22e-149	-	-	-	S	-	-	-	COG NOG23394 non supervised orthologous group
NCOHLEED_00616	3.66e-127	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Conserved protein
NCOHLEED_00617	9.33e-48	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00618	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00619	1.33e-84	-	-	-	S	-	-	-	Protein of unknown function, DUF488
NCOHLEED_00620	1.63e-179	ric	-	-	C	ko:K07322	-	ko00000	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NCOHLEED_00621	5.36e-122	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00622	4.96e-131	-	-	-	M	-	-	-	COG NOG27749 non supervised orthologous group
NCOHLEED_00623	8.12e-123	-	-	-	-	-	-	-	-
NCOHLEED_00624	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
NCOHLEED_00625	4.94e-114	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_00626	1.22e-139	-	-	-	-	-	-	-	-
NCOHLEED_00627	0.0	-	-	-	D	ko:K19171	-	ko00000,ko02048	AAA ATPase domain
NCOHLEED_00628	9e-46	-	-	-	-	-	-	-	-
NCOHLEED_00629	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
NCOHLEED_00630	2.06e-12	-	2.7.11.1	-	T	ko:K13412	ko04626,ko05145,map04626,map05145	ko00000,ko00001,ko01000,ko01001	Protein kinase domain protein
NCOHLEED_00631	2.23e-148	-	-	-	U	-	-	-	Protein of unknown function DUF262
NCOHLEED_00632	4.46e-205	-	-	-	EH	-	-	-	Phosphoadenosine phosphosulfate reductase
NCOHLEED_00633	0.0	-	-	-	LO	-	-	-	Belongs to the peptidase S16 family
NCOHLEED_00634	6.84e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF4007)
NCOHLEED_00635	7.01e-231	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
NCOHLEED_00636	1.2e-136	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00637	7.79e-102	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_00638	4.6e-78	-	-	-	KT	-	-	-	COG COG3279 Response regulator of the LytR AlgR family
NCOHLEED_00639	1.7e-99	-	-	-	-	-	-	-	-
NCOHLEED_00640	1.04e-98	-	-	-	S	-	-	-	COG NOG30410 non supervised orthologous group
NCOHLEED_00641	3.17e-279	madB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	COG COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NCOHLEED_00642	4.45e-260	-	-	-	S	-	-	-	Peptidase M50
NCOHLEED_00643	2.14e-188	ddpX	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NCOHLEED_00644	1.46e-301	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00645	0.0	-	-	-	M	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00646	1.83e-230	-	3.1.3.2	-	S	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	ko00000,ko00001,ko01000	Purple acid phosphatase
NCOHLEED_00647	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4784)
NCOHLEED_00648	0.0	mscM	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00649	1.23e-232	yrbG	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger
NCOHLEED_00650	4.84e-279	yghO	-	-	K	-	-	-	COG NOG07967 non supervised orthologous group
NCOHLEED_00651	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit
NCOHLEED_00652	3.44e-105	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NCOHLEED_00653	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NCOHLEED_00655	7.85e-139	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score
NCOHLEED_00656	1.24e-202	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
NCOHLEED_00657	8.05e-166	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	Succinate dehydrogenase cytochrome B subunit, b558 family
NCOHLEED_00658	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit
NCOHLEED_00659	3.71e-185	frdB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0479 Succinate dehydrogenase fumarate reductase Fe-S protein subunit
NCOHLEED_00660	9.08e-234	-	-	-	K	-	-	-	Transcriptional regulator, AraC family
NCOHLEED_00661	6.03e-222	-	-	-	S	-	-	-	COG NOG31846 non supervised orthologous group
NCOHLEED_00662	1.27e-241	-	-	-	S	-	-	-	COG NOG26135 non supervised orthologous group
NCOHLEED_00663	1.31e-154	-	-	-	M	-	-	-	COG NOG24980 non supervised orthologous group
NCOHLEED_00664	2.06e-190	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	COG0584 Glycerophosphoryl diester phosphodiesterase
NCOHLEED_00665	4.07e-268	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
NCOHLEED_00666	2.3e-98	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
NCOHLEED_00667	4.8e-310	prtC	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
NCOHLEED_00668	5.49e-236	dus	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NCOHLEED_00670	5.91e-233	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00671	1.22e-248	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
NCOHLEED_00672	3.43e-237	fieF	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NCOHLEED_00673	0.0	rnr	-	-	J	ko:K12573,ko:K12585	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NCOHLEED_00674	8.53e-96	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase family protein
NCOHLEED_00675	2.76e-219	cysK	2.5.1.47	-	E	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NCOHLEED_00676	2.55e-216	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.97
NCOHLEED_00677	7.16e-315	rlmL	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NCOHLEED_00678	0.0	pepX2	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
NCOHLEED_00679	7.06e-309	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NCOHLEED_00680	1.99e-236	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00681	1.18e-104	yqaA	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_00682	4.87e-164	mnmC	-	-	S	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00683	2.36e-217	mntA	-	-	P	ko:K09815,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin
NCOHLEED_00684	3.18e-195	znuC	-	-	P	ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NCOHLEED_00685	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00686	0.0	-	-	-	M	-	-	-	Cellulase N-terminal ig-like domain
NCOHLEED_00687	2.55e-314	-	5.1.3.11	-	M	ko:K16213	-	ko00000,ko01000	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
NCOHLEED_00688	0.0	-	-	-	K	-	-	-	Pfam:SusD
NCOHLEED_00689	0.0	-	-	-	P	-	-	-	TonB dependent receptor
NCOHLEED_00690	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
NCOHLEED_00691	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
NCOHLEED_00692	0.0	-	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Cellulase N-terminal ig-like domain
NCOHLEED_00693	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00694	0.0	-	5.1.3.11	-	M	ko:K16213	-	ko00000,ko01000	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
NCOHLEED_00695	0.0	-	-	-	G	-	-	-	Cellulase N-terminal ig-like domain
NCOHLEED_00696	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
NCOHLEED_00697	2.38e-273	-	-	-	S	-	-	-	ATPase (AAA superfamily)
NCOHLEED_00698	1.62e-118	-	-	-	-	-	-	-	-
NCOHLEED_00699	0.0	-	-	-	N	-	-	-	Putative binding domain, N-terminal
NCOHLEED_00702	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00703	1.35e-166	pgdA_1	-	-	G	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00704	3.65e-220	-	-	-	S	-	-	-	Domain of unknown function (DUF4595) with porin-like fold
NCOHLEED_00706	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_00707	1.1e-143	-	-	-	T	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_00708	8.44e-303	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	COG NOG24911 non supervised orthologous group
NCOHLEED_00709	1.84e-193	idnO	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	Oxidoreductase, short chain dehydrogenase reductase family protein
NCOHLEED_00710	5.7e-30	-	-	-	G	-	-	-	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NCOHLEED_00712	7.73e-316	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NCOHLEED_00713	4.33e-160	-	-	-	L	ko:K03424	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00714	7.04e-52	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NCOHLEED_00715	2.71e-84	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NCOHLEED_00716	7.15e-178	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
NCOHLEED_00717	2.38e-168	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_00718	3.93e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NCOHLEED_00719	3.31e-199	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
NCOHLEED_00720	2.4e-120	-	-	-	C	-	-	-	Flavodoxin
NCOHLEED_00721	8.59e-273	-	-	-	S	ko:K06889	-	ko00000	of the alpha beta superfamily
NCOHLEED_00722	6.94e-263	-	-	-	S	-	-	-	COG NOG15865 non supervised orthologous group
NCOHLEED_00723	9.58e-267	-	-	-	S	-	-	-	NPCBM-associated, NEW3 domain of alpha-galactosidase
NCOHLEED_00724	3.41e-175	yxlF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location Cytoplasmic, score 9.12
NCOHLEED_00725	6.73e-217	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NCOHLEED_00727	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
NCOHLEED_00728	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_00729	8.05e-167	-	-	-	S	-	-	-	COG NOG31568 non supervised orthologous group
NCOHLEED_00730	4.28e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
NCOHLEED_00731	1.03e-302	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
NCOHLEED_00732	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3
NCOHLEED_00733	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
NCOHLEED_00734	9.11e-181	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NCOHLEED_00735	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
NCOHLEED_00737	2.01e-209	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
NCOHLEED_00738	5.25e-142	-	-	-	K	-	-	-	Bacterial regulatory protein, Fis family
NCOHLEED_00739	0.0	-	-	-	S	-	-	-	COG NOG28036 non supervised orthologous group
NCOHLEED_00740	3.49e-247	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NCOHLEED_00741	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
NCOHLEED_00742	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00744	2.23e-281	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
NCOHLEED_00745	2.74e-208	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NCOHLEED_00746	2.53e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NCOHLEED_00747	0.0	-	3.1.6.6	-	P	ko:K01133	-	ko00000,ko01000	COG COG3119 Arylsulfatase A and related enzymes
NCOHLEED_00748	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NCOHLEED_00749	2.2e-189	-	-	-	C	-	-	-	4Fe-4S binding domain protein
NCOHLEED_00750	8.14e-303	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NCOHLEED_00751	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NCOHLEED_00752	2.41e-45	-	-	-	-	-	-	-	-
NCOHLEED_00754	3.84e-126	-	-	-	CO	-	-	-	Redoxin family
NCOHLEED_00755	1.5e-172	cypM_1	-	-	H	-	-	-	Methyltransferase domain protein
NCOHLEED_00756	4.09e-32	-	-	-	-	-	-	-	-
NCOHLEED_00757	2.83e-91	gloA	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00758	3.43e-260	-	-	-	S	-	-	-	COG NOG25895 non supervised orthologous group
NCOHLEED_00759	1.34e-179	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00760	3.17e-173	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
NCOHLEED_00761	2.53e-240	ldhA	1.1.1.28	-	C	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCOHLEED_00762	0.0	-	-	-	I	ko:K06076	-	ko00000,ko02000	COG COG2067 Long-chain fatty acid transport protein
NCOHLEED_00763	8.84e-309	-	-	-	S	-	-	-	COG NOG10142 non supervised orthologous group
NCOHLEED_00764	4.86e-282	-	-	-	G	-	-	-	Glyco_18
NCOHLEED_00765	7e-183	-	-	-	-	-	-	-	-
NCOHLEED_00766	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_00767	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00769	9.73e-155	yhhQ	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NCOHLEED_00770	5.24e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NCOHLEED_00771	5.68e-113	queF	1.7.1.13	-	H	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NCOHLEED_00772	5.57e-307	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NCOHLEED_00774	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00775	0.0	-	-	-	E	-	-	-	Domain of unknown function (DUF4374)
NCOHLEED_00776	1.59e-287	piuB	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_00778	6.03e-150	nrfH	-	-	C	ko:K15876	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002	COG COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit
NCOHLEED_00779	0.0	nrfA	1.7.2.2	-	C	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NCOHLEED_00780	1.41e-303	ccs1	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00781	1.52e-199	ycf	-	-	O	-	-	-	COG COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
NCOHLEED_00782	0.0	-	-	-	M	-	-	-	COG NOG37029 non supervised orthologous group
NCOHLEED_00783	5.42e-158	-	-	-	K	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NCOHLEED_00784	7.75e-145	-	-	-	K	-	-	-	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCOHLEED_00785	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
NCOHLEED_00786	1.47e-211	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00787	1.23e-264	romA	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00789	7.49e-198	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Formamidopyrimidine-DNA glycosylase H2TH domain
NCOHLEED_00790	7.68e-112	-	-	-	S	-	-	-	Domain of unknown function (DUF4251)
NCOHLEED_00791	2.67e-164	-	-	-	S	-	-	-	serine threonine protein kinase
NCOHLEED_00792	1.96e-226	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00793	1.05e-202	-	-	-	-	-	-	-	-
NCOHLEED_00794	3.72e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4129)
NCOHLEED_00795	2.57e-291	-	-	-	S	-	-	-	COG NOG26634 non supervised orthologous group
NCOHLEED_00796	7.87e-219	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NCOHLEED_00797	9.35e-311	-	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NCOHLEED_00798	1.33e-227	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
NCOHLEED_00799	9.06e-186	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
NCOHLEED_00800	9.3e-40	-	-	-	T	-	-	-	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCOHLEED_00802	3.71e-67	-	-	-	-	-	-	-	-
NCOHLEED_00803	4.34e-76	-	-	-	-	-	-	-	-
NCOHLEED_00804	1.34e-13	-	-	-	-	-	-	-	-
NCOHLEED_00805	3.14e-157	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
NCOHLEED_00806	3.06e-81	-	-	-	-	-	-	-	-
NCOHLEED_00807	8.85e-131	-	-	-	S	-	-	-	RteC protein
NCOHLEED_00808	2.24e-68	-	-	-	S	-	-	-	Helix-turn-helix domain
NCOHLEED_00809	1.11e-95	-	-	-	-	-	-	-	-
NCOHLEED_00810	2.83e-281	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_00811	1.24e-264	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_00813	2.88e-132	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00814	6.14e-29	-	-	-	-	-	-	-	-
NCOHLEED_00815	9e-181	-	-	-	O	ko:K05801	-	ko00000,ko03110	Psort location Cytoplasmic, score
NCOHLEED_00816	0.0	-	-	-	M	ko:K08676	-	ko00000,ko01000,ko01002	Tricorn protease homolog
NCOHLEED_00817	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00818	5.56e-245	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	COG COG0147 Anthranilate para-aminobenzoate synthases component I
NCOHLEED_00819	9.55e-146	-	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00820	9.71e-76	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_00821	3.27e-312	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NCOHLEED_00822	9.72e-93	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00823	2.67e-183	znuB	-	-	P	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NCOHLEED_00824	3.03e-96	yjeE	-	-	S	ko:K06925	-	ko00000,ko03016	Psort location Cytoplasmic, score
NCOHLEED_00825	5.69e-44	-	-	-	S	-	-	-	COG NOG34862 non supervised orthologous group
NCOHLEED_00826	1.55e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00827	2.02e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NCOHLEED_00828	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
NCOHLEED_00829	4.48e-161	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NCOHLEED_00830	7.14e-166	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NCOHLEED_00831	8.82e-58	-	-	-	S	-	-	-	Domain of unknown function (DUF4834)
NCOHLEED_00832	1.75e-97	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NCOHLEED_00833	7.45e-49	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00834	0.0	-	-	-	M	-	-	-	COG0793 Periplasmic protease
NCOHLEED_00835	5.37e-85	-	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
NCOHLEED_00836	1.97e-81	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00837	2.81e-183	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	biotin acetyl-CoA-carboxylase ligase
NCOHLEED_00838	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 2, sugar binding domain protein
NCOHLEED_00839	0.0	-	-	-	M	-	-	-	COG NOG07608 non supervised orthologous group
NCOHLEED_00840	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_00841	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00842	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00843	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_00844	2.18e-153	-	-	-	S	-	-	-	COG NOG28155 non supervised orthologous group
NCOHLEED_00845	0.0	dinF	-	-	V	ko:K03327	-	ko00000,ko02000	MATE efflux family protein
NCOHLEED_00846	0.0	actP	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00847	1.19e-207	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00848	1.78e-123	-	-	-	M	-	-	-	Nucleoside 2-deoxyribosyltransferase like
NCOHLEED_00849	3.67e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NCOHLEED_00850	4.88e-133	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NCOHLEED_00851	2.14e-217	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NCOHLEED_00852	6.02e-248	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_00853	0.0	bepE_4	-	-	V	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_00854	1.88e-308	tolC	-	-	MU	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00855	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
NCOHLEED_00856	1.66e-294	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00857	0.0	fumB	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
NCOHLEED_00858	0.0	-	-	-	JM	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00859	6.48e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NCOHLEED_00861	1.46e-190	-	-	-	-	-	-	-	-
NCOHLEED_00862	0.0	-	-	-	S	-	-	-	SusD family
NCOHLEED_00863	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00865	2.17e-35	-	-	-	-	-	-	-	-
NCOHLEED_00866	2.46e-98	-	-	-	S	-	-	-	Zeta toxin
NCOHLEED_00867	6.51e-259	-	-	-	G	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_00868	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00869	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	COG NOG25454 non supervised orthologous group
NCOHLEED_00870	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00871	8.86e-35	-	-	-	-	-	-	-	-
NCOHLEED_00872	4.27e-138	-	-	-	S	-	-	-	Zeta toxin
NCOHLEED_00873	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_00874	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00875	0.0	-	-	-	KT	-	-	-	COG NOG11230 non supervised orthologous group
NCOHLEED_00876	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00877	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_00878	0.0	-	-	-	-	-	-	-	-
NCOHLEED_00879	0.0	-	-	-	G	-	-	-	Psort location Extracellular, score
NCOHLEED_00880	1.45e-315	-	-	-	G	-	-	-	beta-galactosidase activity
NCOHLEED_00881	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
NCOHLEED_00882	1.73e-307	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NCOHLEED_00883	1.28e-66	-	-	-	S	-	-	-	Pentapeptide repeat protein
NCOHLEED_00884	8.46e-84	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCOHLEED_00885	2.47e-107	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00886	0.0	susB	3.2.1.20, 3.2.1.3	GH31,GH97	G	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
NCOHLEED_00887	5.04e-230	-	-	-	C	-	-	-	4Fe-4S dicluster domain
NCOHLEED_00888	1.46e-195	-	-	-	K	-	-	-	Transcriptional regulator
NCOHLEED_00889	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine phosphoribosylpyrophosphate amidotransferase
NCOHLEED_00890	7.16e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NCOHLEED_00891	2.56e-275	gcvT	2.1.2.10	-	H	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
NCOHLEED_00892	0.0	-	-	-	S	-	-	-	Peptidase family M48
NCOHLEED_00893	7.19e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NCOHLEED_00894	4.43e-251	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
NCOHLEED_00895	4.94e-244	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_00896	0.0	amyA2	3.2.1.135	GH13	G	ko:K21575	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 13 family
NCOHLEED_00897	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_00898	1.27e-269	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	sodium ion-translocating decarboxylase, beta subunit
NCOHLEED_00899	3.57e-76	mmdC	-	-	I	-	-	-	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NCOHLEED_00900	1.56e-222	-	-	-	C	-	-	-	COG NOG19100 non supervised orthologous group
NCOHLEED_00901	0.0	mmdA	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NCOHLEED_00902	2.84e-115	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00903	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
NCOHLEED_00904	0.0	-	-	-	T	ko:K02481	-	ko00000,ko02022	acetoacetate metabolism regulatory protein AtoC K07714
NCOHLEED_00905	1.13e-307	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_00906	0.0	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	COG COG0436 Aspartate tyrosine aromatic aminotransferase
NCOHLEED_00907	0.0	aspT	-	-	S	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00908	0.0	-	-	-	M	-	-	-	COG NOG06397 non supervised orthologous group
NCOHLEED_00909	0.0	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Inositol-3-phosphate synthase
NCOHLEED_00910	2.61e-106	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_00911	1.51e-126	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_00912	7.45e-150	pgsA1	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NCOHLEED_00913	1.56e-227	-	-	-	I	-	-	-	Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media
NCOHLEED_00914	1.26e-287	-	-	-	C	ko:K19955	-	ko00000,ko01000	Psort location Cytoplasmic, score
NCOHLEED_00915	0.0	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	S1 RNA binding domain
NCOHLEED_00916	6.76e-56	hupA	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
NCOHLEED_00917	9.25e-258	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG1194 A G-specific DNA glycosylase
NCOHLEED_00918	3.19e-105	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
NCOHLEED_00919	1.67e-315	gldE	-	-	S	-	-	-	Gliding motility-associated protein GldE
NCOHLEED_00920	2.08e-152	sfp	-	-	H	-	-	-	Belongs to the P-Pant transferase superfamily
NCOHLEED_00921	0.0	tnaA	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00922	0.0	-	2.7.13.3	-	T	ko:K02484,ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_00923	3.98e-160	srrA	-	-	K	ko:K07657,ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NCOHLEED_00924	5.31e-284	-	-	-	T	-	-	-	COG NOG06399 non supervised orthologous group
NCOHLEED_00926	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_00927	0.0	-	-	-	H	-	-	-	Susd and RagB outer membrane lipoprotein
NCOHLEED_00928	3.89e-194	-	-	-	S	-	-	-	COG NOG25193 non supervised orthologous group
NCOHLEED_00929	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NCOHLEED_00930	1.08e-212	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_00931	3.97e-97	-	-	-	O	-	-	-	Thioredoxin
NCOHLEED_00932	2.34e-66	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Psort location Cytoplasmic, score
NCOHLEED_00933	0.0	-	-	-	S	-	-	-	COG NOG06390 non supervised orthologous group
NCOHLEED_00934	0.0	dpp11	-	-	E	-	-	-	COG NOG04781 non supervised orthologous group
NCOHLEED_00935	0.0	atsB	-	-	C	ko:K06871	-	ko00000	COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
NCOHLEED_00936	2.03e-169	-	-	-	CO	-	-	-	Domain of unknown function (DUF4369)
NCOHLEED_00937	4.19e-65	-	-	-	S	-	-	-	Nucleotidyltransferase domain
NCOHLEED_00938	7.11e-46	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00940	8.64e-276	-	-	-	S	ko:K06921	-	ko00000	ATPase (AAA superfamily)
NCOHLEED_00941	6.24e-78	-	-	-	-	-	-	-	-
NCOHLEED_00942	0.0	-	-	-	N	-	-	-	COG NOG14601 non supervised orthologous group
NCOHLEED_00943	4.84e-230	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_00944	2.49e-180	-	-	-	-	-	-	-	-
NCOHLEED_00945	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
NCOHLEED_00946	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NCOHLEED_00947	1.07e-303	waaA	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Psort location Cytoplasmic, score 8.96
NCOHLEED_00948	7.94e-97	dapH	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
NCOHLEED_00949	0.0	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
NCOHLEED_00950	1.73e-32	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NCOHLEED_00951	5.11e-209	xerC	-	-	D	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NCOHLEED_00952	2.63e-59	raiA	-	-	J	ko:K05808	-	ko00000,ko03009	Ribosomal subunit interface protein
NCOHLEED_00956	8.89e-290	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NCOHLEED_00958	2.49e-123	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NCOHLEED_00959	1.04e-99	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NCOHLEED_00960	5.85e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NCOHLEED_00961	1.24e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L10
NCOHLEED_00962	6.3e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NCOHLEED_00963	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCOHLEED_00964	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCOHLEED_00965	1.18e-66	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_00966	1.66e-87	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NCOHLEED_00967	5.42e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NCOHLEED_00968	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NCOHLEED_00969	6.63e-63	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NCOHLEED_00970	3.19e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NCOHLEED_00971	1.76e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NCOHLEED_00972	8.23e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NCOHLEED_00973	1.34e-194	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NCOHLEED_00974	1.49e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NCOHLEED_00975	3.59e-88	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NCOHLEED_00976	4.12e-169	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NCOHLEED_00977	1.32e-96	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NCOHLEED_00978	8.68e-36	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NCOHLEED_00979	9.63e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NCOHLEED_00980	3.93e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NCOHLEED_00981	2.16e-68	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NCOHLEED_00982	1.73e-121	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NCOHLEED_00983	9.52e-62	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NCOHLEED_00984	2.47e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NCOHLEED_00985	2.88e-131	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NCOHLEED_00986	2.09e-72	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NCOHLEED_00987	3.17e-113	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NCOHLEED_00988	3e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L30
NCOHLEED_00989	1.72e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NCOHLEED_00990	2.12e-308	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NCOHLEED_00991	5.08e-195	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
NCOHLEED_00992	1.98e-44	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NCOHLEED_00993	1.06e-18	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NCOHLEED_00994	1.77e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NCOHLEED_00995	1.01e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NCOHLEED_00996	1.07e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NCOHLEED_00997	3.41e-232	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCOHLEED_00998	4.95e-90	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NCOHLEED_00999	4.97e-86	-	-	-	S	-	-	-	COG NOG31702 non supervised orthologous group
NCOHLEED_01000	2.19e-117	-	-	-	S	-	-	-	COG NOG27987 non supervised orthologous group
NCOHLEED_01001	0.0	mutS_2	-	-	L	-	-	-	DNA mismatch repair protein MutS
NCOHLEED_01002	6.38e-167	-	-	-	S	-	-	-	COG NOG29571 non supervised orthologous group
NCOHLEED_01003	1.3e-108	-	-	-	-	-	-	-	-
NCOHLEED_01004	2.15e-139	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01005	1.72e-54	-	-	-	S	-	-	-	COG NOG18433 non supervised orthologous group
NCOHLEED_01006	1.39e-11	-	-	-	-	-	-	-	-
NCOHLEED_01007	5.19e-105	-	-	-	S	-	-	-	Lipocalin-like
NCOHLEED_01008	0.0	hutU	4.2.1.49	-	H	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NCOHLEED_01009	1.07e-210	ftcD	2.1.2.5, 4.3.1.4	-	E	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	ko00000,ko00001,ko01000,ko03036,ko04147	Glutamate formiminotransferase
NCOHLEED_01010	4.19e-302	hutI	3.5.2.7	-	F	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
NCOHLEED_01011	1.01e-134	fchA	-	-	E	-	-	-	COG3404 Methenyl tetrahydrofolate cyclohydrolase
NCOHLEED_01012	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
NCOHLEED_01013	4.32e-155	-	-	-	K	-	-	-	transcriptional regulator, TetR family
NCOHLEED_01014	3.15e-312	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
NCOHLEED_01015	1.18e-236	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_01016	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_01017	1.37e-60	-	-	-	E	-	-	-	COG NOG19114 non supervised orthologous group
NCOHLEED_01018	0.0	-	-	-	E	-	-	-	COG COG2755 Lysophospholipase L1 and related esterases
NCOHLEED_01019	3.71e-226	-	-	-	E	-	-	-	COG NOG14456 non supervised orthologous group
NCOHLEED_01020	0.0	algI	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01021	0.0	nagZ2	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
NCOHLEED_01022	2.07e-200	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
NCOHLEED_01023	4.73e-249	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_01024	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_01025	6.42e-315	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
NCOHLEED_01026	1.06e-178	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NCOHLEED_01027	1.05e-40	-	-	-	-	-	-	-	-
NCOHLEED_01028	9.92e-143	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01029	8.58e-139	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01030	4.97e-40	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NCOHLEED_01031	4.59e-248	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NCOHLEED_01032	5.52e-208	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NCOHLEED_01033	3.16e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NCOHLEED_01034	6.38e-184	metN	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NCOHLEED_01035	3.78e-167	mlaE	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01036	1.39e-195	lptB	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score 9.12
NCOHLEED_01037	6.63e-52	-	-	-	S	-	-	-	COG COG0724 RNA-binding proteins (RRM domain)
NCOHLEED_01038	1.28e-311	tig	-	-	O	ko:K03545	-	ko00000	peptidyl-prolyl cis-trans isomerase (trigger factor)
NCOHLEED_01039	5.04e-154	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NCOHLEED_01040	1.24e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NCOHLEED_01041	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NCOHLEED_01043	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NCOHLEED_01044	0.0	-	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	COG COG0760 Parvulin-like peptidyl-prolyl isomerase
NCOHLEED_01045	1.59e-206	-	-	-	O	-	-	-	COG NOG23400 non supervised orthologous group
NCOHLEED_01046	0.0	surA	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	peptidylprolyl isomerase
NCOHLEED_01047	2.97e-312	lptD	-	-	M	-	-	-	COG NOG06415 non supervised orthologous group
NCOHLEED_01048	2.67e-62	-	-	-	S	-	-	-	COG NOG23401 non supervised orthologous group
NCOHLEED_01049	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NCOHLEED_01050	9.05e-281	-	-	-	M	-	-	-	Psort location OuterMembrane, score
NCOHLEED_01051	1.03e-266	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NCOHLEED_01052	5.57e-149	-	-	-	L	-	-	-	COG NOG29822 non supervised orthologous group
NCOHLEED_01053	1.26e-17	-	-	-	-	-	-	-	-
NCOHLEED_01054	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
NCOHLEED_01055	0.0	-	-	-	-	-	-	-	-
NCOHLEED_01056	0.0	-	-	-	L	-	-	-	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
NCOHLEED_01057	4.79e-308	-	-	-	D	-	-	-	plasmid recombination enzyme
NCOHLEED_01058	2.84e-241	-	-	-	L	-	-	-	Toprim-like
NCOHLEED_01059	8.41e-300	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01060	1.76e-86	-	-	-	S	-	-	-	COG3943, virulence protein
NCOHLEED_01061	1.7e-300	-	-	-	L	-	-	-	COG4974 Site-specific recombinase XerD
NCOHLEED_01062	9.63e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Psort location Cytoplasmic, score 9.97
NCOHLEED_01065	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_01066	7.96e-249	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NCOHLEED_01067	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
NCOHLEED_01068	9.57e-119	-	-	-	S	-	-	-	COG NOG27649 non supervised orthologous group
NCOHLEED_01069	4.7e-108	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NCOHLEED_01070	3.54e-82	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NCOHLEED_01071	3.51e-187	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NCOHLEED_01072	4.26e-226	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NCOHLEED_01073	8.75e-78	-	-	-	J	ko:K03113	ko03013,map03013	ko00000,ko00001,ko03012	COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related
NCOHLEED_01074	8.38e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NCOHLEED_01075	1.21e-149	fahA	-	-	Q	-	-	-	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, fumarylacetoacetate hydrolase family K01828
NCOHLEED_01076	5.04e-244	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01077	0.0	-	-	-	P	ko:K21573	-	ko00000,ko02000	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_01078	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_01079	1.12e-261	-	-	-	G	-	-	-	Histidine acid phosphatase
NCOHLEED_01080	3.01e-107	ispF	4.6.1.12	-	H	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NCOHLEED_01081	1.43e-253	-	-	-	S	-	-	-	Ser Thr phosphatase family protein
NCOHLEED_01082	7.91e-262	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NCOHLEED_01083	1.52e-206	-	-	-	S	-	-	-	COG NOG24904 non supervised orthologous group
NCOHLEED_01084	8.75e-260	-	-	-	P	-	-	-	phosphate-selective porin
NCOHLEED_01085	0.0	-	-	-	S	-	-	-	candidate xyloglucanase, glycoside hydrolase family 74 protein K01238
NCOHLEED_01086	0.0	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
NCOHLEED_01088	0.0	-	-	-	S	-	-	-	Carboxypeptidase regulatory-like domain
NCOHLEED_01089	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 76
NCOHLEED_01090	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_01091	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	COG NOG30008 non supervised orthologous group
NCOHLEED_01092	1.29e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF3823)
NCOHLEED_01093	0.0	-	-	-	S	-	-	-	COG NOG26804 non supervised orthologous group
NCOHLEED_01094	0.0	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
NCOHLEED_01095	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
NCOHLEED_01096	4e-255	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
NCOHLEED_01097	0.0	-	-	-	S	ko:K09704	-	ko00000	Conserved protein
NCOHLEED_01098	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
NCOHLEED_01099	3.91e-270	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01100	3.77e-250	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NCOHLEED_01101	0.0	aprN	-	-	M	-	-	-	Belongs to the peptidase S8 family
NCOHLEED_01102	1.88e-290	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NCOHLEED_01103	2.03e-92	-	-	-	S	-	-	-	Lipocalin-like domain
NCOHLEED_01104	1.42e-39	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NCOHLEED_01105	3.97e-256	ilvE	2.6.1.42	-	EH	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase
NCOHLEED_01106	4.87e-186	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NCOHLEED_01107	3.88e-251	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NCOHLEED_01108	0.0	-	-	-	U	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NCOHLEED_01109	1.32e-80	-	-	-	K	-	-	-	Transcriptional regulator
NCOHLEED_01110	1.23e-29	-	-	-	-	-	-	-	-
NCOHLEED_01111	0.0	-	-	-	S	-	-	-	Oxidoreductase NAD-binding domain protein
NCOHLEED_01112	0.0	-	-	-	CO	-	-	-	COG NOG24773 non supervised orthologous group
NCOHLEED_01113	1.24e-258	-	-	-	E	-	-	-	COG NOG09493 non supervised orthologous group
NCOHLEED_01114	5.87e-295	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01115	2.33e-282	-	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01116	3.18e-216	-	-	-	M	ko:K01993	-	ko00000	Auxiliary transport protein, membrane fusion protein (MFP) family protein
NCOHLEED_01117	3.23e-311	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
NCOHLEED_01118	7.02e-190	-	-	-	S	-	-	-	COG NOG11650 non supervised orthologous group
NCOHLEED_01119	3.92e-218	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
NCOHLEED_01120	0.0	-	-	-	M	-	-	-	Tricorn protease homolog
NCOHLEED_01121	0.0	-	-	-	G	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NCOHLEED_01122	0.0	-	-	-	K	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_01123	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_01124	9.12e-246	-	-	-	PT	-	-	-	COG3712 Fe2 -dicitrate sensor, membrane component
NCOHLEED_01125	4.28e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog
NCOHLEED_01126	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
NCOHLEED_01127	1.29e-183	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 35 family
NCOHLEED_01128	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
NCOHLEED_01129	0.0	-	3.2.1.31	-	M	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
NCOHLEED_01130	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
NCOHLEED_01131	0.0	-	-	-	G	-	-	-	COG COG3345 Alpha-galactosidase
NCOHLEED_01132	0.0	-	-	-	Q	-	-	-	FAD dependent oxidoreductase
NCOHLEED_01133	1.33e-241	-	-	-	PT	-	-	-	COG3712 Fe2 -dicitrate sensor, membrane component
NCOHLEED_01134	6.21e-128	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
NCOHLEED_01135	1.21e-209	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NCOHLEED_01136	1.9e-171	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NCOHLEED_01137	5.21e-165	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
NCOHLEED_01138	2.16e-89	-	-	-	U	ko:K03559	-	ko00000,ko02000	Transport energizing protein, ExbD TolR family
NCOHLEED_01139	2.86e-163	-	-	-	M	-	-	-	TonB family domain protein
NCOHLEED_01140	1.33e-129	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
NCOHLEED_01141	1.57e-159	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NCOHLEED_01142	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NCOHLEED_01143	8.46e-211	mepM_1	-	-	M	-	-	-	Peptidase, M23
NCOHLEED_01144	5.23e-125	-	-	-	S	-	-	-	COG NOG27206 non supervised orthologous group
NCOHLEED_01145	1.83e-314	doxX	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01146	1.49e-175	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NCOHLEED_01147	1.64e-103	-	-	-	S	-	-	-	Sporulation and cell division repeat protein
NCOHLEED_01148	3.1e-138	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase I
NCOHLEED_01149	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NCOHLEED_01150	1.28e-179	tyrA	1.3.1.12	-	E	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
NCOHLEED_01151	5.26e-260	pheB	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01152	7.13e-300	dapL	2.6.1.83	-	E	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	COG0436 Aspartate tyrosine aromatic aminotransferase
NCOHLEED_01153	4.55e-206	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_01154	8.05e-179	-	-	-	S	-	-	-	phosphatase family
NCOHLEED_01155	9.43e-160	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01156	0.0	recQ2	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NCOHLEED_01157	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	single-stranded-DNA-specific exonuclease recJ
NCOHLEED_01158	9.1e-189	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NCOHLEED_01159	8.2e-245	-	4.6.1.13	-	U	ko:K01771	ko00562,map00562	ko00000,ko00001,ko01000	Phosphatidylinositol-specific phospholipase C, X domain
NCOHLEED_01160	3.77e-194	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NCOHLEED_01161	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_01162	0.0	-	-	-	J	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_01163	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
NCOHLEED_01164	5.57e-214	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
NCOHLEED_01165	2.34e-273	phoA	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
NCOHLEED_01166	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 63 C-terminal domain
NCOHLEED_01167	0.0	-	-	-	S	ko:K09704	-	ko00000	Conserved protein
NCOHLEED_01168	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
NCOHLEED_01169	0.0	-	-	-	S	-	-	-	PA14 domain protein
NCOHLEED_01170	1.53e-288	-	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional regulator (AraC family)
NCOHLEED_01171	8.62e-102	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
NCOHLEED_01172	3.03e-120	rimN	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
NCOHLEED_01173	0.0	-	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01174	1.45e-234	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NCOHLEED_01175	1.45e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01176	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01177	7.72e-257	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHH family
NCOHLEED_01178	3.73e-143	-	-	-	S	-	-	-	COG NOG30041 non supervised orthologous group
NCOHLEED_01179	0.0	glmM	5.4.2.8	-	G	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01180	4.79e-307	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
NCOHLEED_01181	8.88e-122	idi	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01182	2.72e-303	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NCOHLEED_01183	1.95e-252	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01184	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NCOHLEED_01185	1.82e-254	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
NCOHLEED_01186	0.0	-	-	-	T	-	-	-	Forkhead associated domain
NCOHLEED_01187	0.0	-	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NCOHLEED_01188	3.48e-143	-	-	-	S	-	-	-	Double zinc ribbon
NCOHLEED_01189	2.79e-178	-	-	-	S	-	-	-	Putative binding domain, N-terminal
NCOHLEED_01190	0.0	-	2.7.11.1	-	KLT	ko:K08838,ko:K12132	-	ko00000,ko01000,ko01001,ko04131	Protein tyrosine kinase
NCOHLEED_01191	0.0	-	-	-	T	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_01192	8.03e-179	-	-	-	T	ko:K02477	-	ko00000,ko02022	COG3279 Response regulator of the LytR AlgR family
NCOHLEED_01193	2.32e-75	-	-	-	S	-	-	-	COG NOG30654 non supervised orthologous group
NCOHLEED_01194	5.51e-235	-	-	-	S	-	-	-	COG NOG27441 non supervised orthologous group
NCOHLEED_01195	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
NCOHLEED_01196	5.71e-116	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
NCOHLEED_01197	1.23e-119	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
NCOHLEED_01198	1.24e-280	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NCOHLEED_01200	0.0	-	-	-	O	-	-	-	protein conserved in bacteria
NCOHLEED_01201	0.0	-	-	-	S	-	-	-	COG NOG19133 non supervised orthologous group
NCOHLEED_01202	5.32e-295	-	-	-	E	-	-	-	Glycosyl Hydrolase Family 88
NCOHLEED_01203	0.0	-	-	-	G	-	-	-	hydrolase, family 43
NCOHLEED_01204	0.0	-	-	-	G	-	-	-	COG NOG26813 non supervised orthologous group
NCOHLEED_01205	0.0	-	-	-	G	-	-	-	Carbohydrate binding domain protein
NCOHLEED_01206	0.0	-	-	-	S	ko:K09955	-	ko00000	protein conserved in bacteria
NCOHLEED_01207	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Carbohydrate binding domain protein
NCOHLEED_01208	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
NCOHLEED_01209	1.82e-295	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
NCOHLEED_01210	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
NCOHLEED_01211	8.24e-110	-	-	-	S	-	-	-	COG NOG19145 non supervised orthologous group
NCOHLEED_01212	0.0	-	-	-	T	-	-	-	adenylate cyclase carring two-component hybrid sensor and regulator domains
NCOHLEED_01213	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_01214	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_01215	1.09e-298	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NCOHLEED_01216	2.47e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG COG2818 3-methyladenine DNA glycosylase
NCOHLEED_01217	1.73e-291	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
NCOHLEED_01218	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 35 family
NCOHLEED_01219	0.0	-	3.4.13.19	-	E	ko:K01273,ko:K01274	-	ko00000,ko00537,ko01000,ko01002,ko04147	Renal dipeptidase family protein
NCOHLEED_01220	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Psort location Cytoplasmic, score 9.26
NCOHLEED_01221	0.0	rprX	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	two-component regulatory system, sensor kinase protein
NCOHLEED_01222	3.54e-165	rprY	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NCOHLEED_01223	5.66e-29	-	-	-	-	-	-	-	-
NCOHLEED_01224	3.21e-99	ohrR	-	-	K	-	-	-	Transcriptional regulator, MarR family
NCOHLEED_01225	3.6e-73	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NCOHLEED_01226	1.54e-56	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NCOHLEED_01227	6.19e-93	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NCOHLEED_01229	1.03e-50	-	-	-	S	-	-	-	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
NCOHLEED_01230	3.27e-19	-	-	-	S	-	-	-	COG NOG38865 non supervised orthologous group
NCOHLEED_01231	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location CytoplasmicMembrane, score 9.82
NCOHLEED_01232	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	Psort location Cytoplasmic, score 8.96
NCOHLEED_01233	2.06e-212	waaM	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Lipid A biosynthesis (KDO)2-(Lauroyl)-lipid IVA acyltransferase
NCOHLEED_01234	7.32e-247	-	-	-	S	ko:K07011	-	ko00000	Glycosyl transferase family group 2
NCOHLEED_01235	2.73e-123	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
NCOHLEED_01236	4.25e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NCOHLEED_01237	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.26
NCOHLEED_01238	0.0	nrd	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
NCOHLEED_01239	7.76e-187	-	1.5.1.38, 1.5.1.39	-	C	ko:K19285,ko:K19286	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Nitroreductase family
NCOHLEED_01240	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NCOHLEED_01241	2.08e-189	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
NCOHLEED_01242	5.69e-265	amiA	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
NCOHLEED_01243	8.99e-226	-	-	-	S	ko:K03453	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01244	2.09e-52	-	-	-	-	-	-	-	-
NCOHLEED_01245	3.08e-128	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NCOHLEED_01247	7.8e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NCOHLEED_01248	6.35e-56	-	-	-	-	-	-	-	-
NCOHLEED_01249	8.76e-236	ykoT	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NCOHLEED_01250	2.32e-72	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_01251	0.0	arnT	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01252	3.56e-131	-	-	-	H	ko:K06950	-	ko00000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01254	0.0	-	-	-	M	-	-	-	Psort location OuterMembrane, score 9.49
NCOHLEED_01255	9.51e-168	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NCOHLEED_01256	1.66e-307	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 10.00
NCOHLEED_01258	1.11e-152	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NCOHLEED_01259	8.68e-106	-	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCOHLEED_01260	9.16e-203	-	-	-	KT	-	-	-	MerR, DNA binding
NCOHLEED_01261	6.25e-214	-	-	-	S	ko:K07017	-	ko00000	Putative esterase
NCOHLEED_01262	2.11e-98	-	-	-	S	-	-	-	COG NOG14442 non supervised orthologous group
NCOHLEED_01263	7.21e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01264	1.42e-212	yfbT	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NCOHLEED_01265	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NCOHLEED_01266	1.78e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NCOHLEED_01267	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NCOHLEED_01268	2.71e-313	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01269	8.78e-150	-	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01270	1.1e-234	-	-	-	M	-	-	-	Right handed beta helix region
NCOHLEED_01271	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01272	0.0	mutA	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	methylmalonyl-CoA mutase small subunit
NCOHLEED_01273	0.0	mutB	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01274	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	COG0550 Topoisomerase IA
NCOHLEED_01275	1.38e-131	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01276	3.09e-270	anmK	2.7.1.170	-	F	ko:K09001	-	ko00000,ko01000	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NCOHLEED_01277	0.0	dapE	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01278	2.07e-263	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NCOHLEED_01279	5.73e-311	-	-	-	S	-	-	-	Domain of unknown function (DUF4925)
NCOHLEED_01280	3.17e-297	-	-	-	S	-	-	-	Belongs to the UPF0597 family
NCOHLEED_01281	1.8e-130	slyD	5.2.1.8	-	G	ko:K03775	-	ko00000,ko01000,ko03110	Psort location Cytoplasmic, score
NCOHLEED_01282	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
NCOHLEED_01283	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase, large subunit
NCOHLEED_01284	1.36e-126	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG0440 Acetolactate synthase, small (regulatory) subunit
NCOHLEED_01285	9.44e-183	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NCOHLEED_01286	3.53e-254	ilvC	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ketol-acid reductoisomerase
NCOHLEED_01287	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01288	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_01289	1.25e-285	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_01290	0.0	prpC	2.3.3.1, 2.3.3.5	-	C	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_01291	9.83e-188	-	1.3.1.22	-	S	ko:K12343	ko00140,map00140	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01292	7.79e-302	-	-	-	C	-	-	-	Oxidoreductase, FAD FMN-binding protein
NCOHLEED_01293	7.49e-199	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
NCOHLEED_01294	1.45e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NCOHLEED_01295	1.71e-204	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NCOHLEED_01296	4.13e-189	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NCOHLEED_01297	1.38e-155	-	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NCOHLEED_01298	5.56e-246	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NCOHLEED_01299	4.49e-168	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01300	4.51e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NCOHLEED_01302	6.82e-164	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
NCOHLEED_01303	4.59e-103	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01304	6.69e-129	-	-	-	U	-	-	-	COG NOG14449 non supervised orthologous group
NCOHLEED_01305	2.62e-89	-	-	-	U	ko:K03559	-	ko00000,ko02000	COG NOG14448 non supervised orthologous group
NCOHLEED_01306	7.47e-133	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01307	0.0	-	-	-	S	-	-	-	IgA Peptidase M64
NCOHLEED_01308	8.67e-111	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	transcriptional regulator, AsnC family
NCOHLEED_01309	6.55e-117	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NCOHLEED_01310	2.84e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NCOHLEED_01311	9.9e-288	cls	-	-	M	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NCOHLEED_01312	5.26e-70	-	-	-	S	-	-	-	Domain of unknown function (DUF5056)
NCOHLEED_01313	4.27e-126	rpoE	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NCOHLEED_01314	2.07e-140	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01315	1.19e-18	-	-	-	-	-	-	-	-
NCOHLEED_01317	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
NCOHLEED_01318	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
NCOHLEED_01319	4.01e-301	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
NCOHLEED_01320	9.11e-281	-	-	-	MU	-	-	-	outer membrane efflux protein
NCOHLEED_01321	0.0	czcA	-	-	P	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_01322	9.84e-252	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_01323	2e-94	-	-	-	S	-	-	-	COG NOG32090 non supervised orthologous group
NCOHLEED_01324	0.0	merA	-	-	C	ko:K21739	-	ko00000	COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NCOHLEED_01325	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	Psort location CytoplasmicMembrane, score
NCOHLEED_01326	1.48e-90	divK	-	-	T	-	-	-	Response regulator receiver domain protein
NCOHLEED_01327	3.03e-192	-	-	-	-	-	-	-	-
NCOHLEED_01328	0.0	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
NCOHLEED_01329	0.0	-	-	-	U	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01330	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NCOHLEED_01331	2.37e-120	-	-	-	S	ko:K07095	-	ko00000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01332	1.5e-180	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NCOHLEED_01333	2.52e-283	-	-	-	S	ko:K07098	-	ko00000	Ser Thr phosphatase family protein
NCOHLEED_01334	2.36e-128	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01335	5.77e-105	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NCOHLEED_01337	1.83e-224	metH_2	-	-	E	-	-	-	Vitamin B12 dependent methionine synthase, activation domain
NCOHLEED_01338	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_01339	1.29e-185	dpm1	2.4.1.83	GT2	S	ko:K00721	ko00510,ko01100,map00510,map01100	ko00000,ko00001,ko01000,ko01003	b-glycosyltransferase, glycosyltransferase family 2 protein
NCOHLEED_01340	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NCOHLEED_01341	6.45e-163	-	-	-	-	-	-	-	-
NCOHLEED_01342	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01343	2.49e-47	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
NCOHLEED_01344	1.08e-67	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01345	0.0	xly	-	-	M	-	-	-	fibronectin type III domain protein
NCOHLEED_01346	4.56e-211	-	-	-	S	-	-	-	Domain of unknown function (DUF4886)
NCOHLEED_01347	0.0	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01348	2.2e-159	-	-	-	S	ko:K09797	-	ko00000	Protein of unknown function (DUF541)
NCOHLEED_01349	4.35e-197	ramA_1	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	hydrolase, carbon-nitrogen family
NCOHLEED_01350	3.67e-136	-	-	-	I	-	-	-	Acyltransferase
NCOHLEED_01351	2.48e-57	-	-	-	S	-	-	-	COG NOG23371 non supervised orthologous group
NCOHLEED_01352	7.95e-290	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_01353	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_01354	0.0	-	-	-	M	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Efflux transporter, outer membrane factor lipoprotein, NodT family
NCOHLEED_01355	4.01e-99	cspG	-	-	K	-	-	-	Cold-shock DNA-binding domain protein
NCOHLEED_01356	2.92e-66	-	-	-	S	-	-	-	RNA recognition motif
NCOHLEED_01357	0.0	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
NCOHLEED_01358	2.53e-200	acm	-	-	M	ko:K07273	-	ko00000	phage tail component domain protein
NCOHLEED_01359	4.54e-205	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
NCOHLEED_01360	2.48e-180	-	-	-	S	-	-	-	Psort location OuterMembrane, score
NCOHLEED_01361	0.0	-	-	-	I	-	-	-	Psort location OuterMembrane, score
NCOHLEED_01362	7.11e-224	-	-	-	-	-	-	-	-
NCOHLEED_01363	5.23e-102	-	-	-	-	-	-	-	-
NCOHLEED_01364	4.34e-99	-	-	-	C	-	-	-	lyase activity
NCOHLEED_01365	5.92e-119	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NCOHLEED_01366	2.79e-136	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01367	2.2e-104	fur	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NCOHLEED_01368	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NCOHLEED_01369	7.44e-193	-	-	-	ET	-	-	-	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain
NCOHLEED_01370	0.0	-	-	-	H	-	-	-	COG NOG07963 non supervised orthologous group
NCOHLEED_01371	1.38e-125	porG	1.2.7.3	-	C	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid ferredoxin flavodoxin oxidoreductase, gamma subunit
NCOHLEED_01372	4.51e-187	vorA	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
NCOHLEED_01373	1.91e-31	-	-	-	-	-	-	-	-
NCOHLEED_01374	2.31e-257	vorB	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
NCOHLEED_01375	2.57e-37	oorD	1.2.7.3	-	C	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	4Fe-4S binding domain protein
NCOHLEED_01376	1.04e-59	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_01377	2.56e-108	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
NCOHLEED_01378	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
NCOHLEED_01379	0.0	abf2	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase domain protein
NCOHLEED_01380	0.0	araB	-	-	G	-	-	-	Carbohydrate kinase, FGGY family protein
NCOHLEED_01381	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NCOHLEED_01382	6.41e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NCOHLEED_01383	2.06e-160	-	-	-	F	-	-	-	NUDIX domain
NCOHLEED_01384	0.0	-	-	-	S	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NCOHLEED_01385	2.75e-281	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
NCOHLEED_01386	3.58e-284	galK	2.7.1.6	-	H	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
NCOHLEED_01387	5.79e-305	gluP	-	-	G	ko:K02429	-	ko00000,ko02000	Transporter, major facilitator family protein
NCOHLEED_01388	2.29e-296	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
NCOHLEED_01389	2.15e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01390	1.07e-52	-	-	-	S	-	-	-	COG NOG35393 non supervised orthologous group
NCOHLEED_01391	1.8e-54	-	-	-	S	-	-	-	COG NOG30994 non supervised orthologous group
NCOHLEED_01392	1.69e-37	-	-	-	S	-	-	-	COG NOG35214 non supervised orthologous group
NCOHLEED_01393	2.25e-301	rhlE	3.6.4.13	-	JKL	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Belongs to the DEAD box helicase family
NCOHLEED_01394	3.08e-95	-	-	-	S	-	-	-	Lipocalin-like domain
NCOHLEED_01395	1.03e-106	-	-	-	D	-	-	-	Sporulation and cell division repeat protein
NCOHLEED_01396	2.63e-201	cysQ	3.1.3.7	-	P	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	ko00000,ko00001,ko01000,ko03016	3'(2'),5'-bisphosphate nucleotidase
NCOHLEED_01397	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01398	8.47e-139	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
NCOHLEED_01399	2.78e-222	cysD	2.7.7.4	-	H	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase
NCOHLEED_01400	0.0	cysN	2.7.1.25, 2.7.7.4	-	H	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
NCOHLEED_01401	1.09e-279	-	-	-	S	-	-	-	COG NOG10884 non supervised orthologous group
NCOHLEED_01402	1.24e-237	-	-	-	S	-	-	-	COG NOG26583 non supervised orthologous group
NCOHLEED_01403	0.0	-	-	-	M	ko:K02014	-	ko00000,ko02000	Psort location OuterMembrane, score 10.00
NCOHLEED_01404	4.82e-254	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01405	0.0	prtQ	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
NCOHLEED_01406	1.5e-227	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NCOHLEED_01407	0.0	-	-	-	S	-	-	-	Fibrobacter succinogenes major domain (Fib_succ_major)
NCOHLEED_01408	2.55e-233	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_01409	1.05e-276	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG2812 DNA polymerase III gamma tau subunits
NCOHLEED_01410	1.29e-276	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
NCOHLEED_01411	5.9e-112	gldH	-	-	M	-	-	-	Gliding motility-associated lipoprotein, GldH
NCOHLEED_01412	0.0	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NCOHLEED_01413	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein 2
NCOHLEED_01414	6.98e-110	mreD	-	-	S	-	-	-	rod shape-determining protein MreD
NCOHLEED_01415	5.28e-200	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NCOHLEED_01416	2.63e-241	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
NCOHLEED_01417	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	bifunctional purine biosynthesis protein PurH
NCOHLEED_01418	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NCOHLEED_01419	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NCOHLEED_01420	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_01421	1.46e-202	-	-	-	K	-	-	-	Helix-turn-helix domain
NCOHLEED_01422	2.15e-192	-	-	-	Q	-	-	-	COG NOG10855 non supervised orthologous group
NCOHLEED_01423	1.27e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF3795)
NCOHLEED_01424	2.33e-236	-	-	-	CO	-	-	-	COG NOG24939 non supervised orthologous group
NCOHLEED_01425	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4906)
NCOHLEED_01427	8.39e-233	-	-	-	S	-	-	-	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
NCOHLEED_01428	4.92e-270	-	-	-	-	-	-	-	-
NCOHLEED_01429	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
NCOHLEED_01430	8.23e-142	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
NCOHLEED_01431	1.89e-226	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_01432	1.82e-227	-	-	-	JM	-	-	-	COG NOG09722 non supervised orthologous group
NCOHLEED_01433	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
NCOHLEED_01434	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.49
NCOHLEED_01435	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_01436	0.0	norM	-	-	V	ko:K03327	-	ko00000,ko02000	MATE efflux family protein
NCOHLEED_01437	5.71e-302	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Peptidase M16 inactive domain protein
NCOHLEED_01438	1.02e-196	ppiA	5.2.1.8	-	M	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NCOHLEED_01439	0.0	-	-	-	T	ko:K07713	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
NCOHLEED_01440	4.59e-06	-	-	-	-	-	-	-	-
NCOHLEED_01441	0.0	-	-	-	EU	-	-	-	Peptidase, S9A B C family, catalytic domain protein
NCOHLEED_01442	1.76e-160	rluC	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	ribosomal pseudouridine synthase C, large subunit
NCOHLEED_01443	5.8e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	with different specificities (related to short-chain alcohol
NCOHLEED_01444	6.23e-133	qacR	-	-	K	-	-	-	transcriptional regulator, TetR family
NCOHLEED_01446	2.87e-289	dcuB	-	-	S	ko:K07791,ko:K07792	ko02020,map02020	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01447	1.92e-200	-	-	-	-	-	-	-	-
NCOHLEED_01448	5.35e-81	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01449	9.55e-205	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01450	2.93e-198	cbiO	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
NCOHLEED_01451	1.05e-224	-	-	-	K	ko:K18954	-	ko00000,ko03000	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family) K00567
NCOHLEED_01452	0.0	-	-	-	S	-	-	-	tetratricopeptide repeat
NCOHLEED_01453	4.42e-221	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	COG0226 ABC-type phosphate transport system, periplasmic component
NCOHLEED_01454	2.47e-184	tonB2	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NCOHLEED_01455	1.05e-144	exbD2	-	-	U	-	-	-	Biopolymer transport protein ExbD/TolR
NCOHLEED_01456	9.85e-123	exbD1	-	-	U	-	-	-	Biopolymer transport protein ExbD/TolR
NCOHLEED_01457	2.56e-181	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
NCOHLEED_01458	3.09e-97	-	-	-	-	-	-	-	-
NCOHLEED_01460	0.0	-	-	-	M	-	-	-	TIGRFAM YD repeat
NCOHLEED_01462	1.42e-110	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
NCOHLEED_01463	1.85e-98	-	-	-	L	-	-	-	COG NOG31286 non supervised orthologous group
NCOHLEED_01464	3.99e-198	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
NCOHLEED_01465	2.38e-70	-	-	-	-	-	-	-	-
NCOHLEED_01466	5.1e-29	-	-	-	-	-	-	-	-
NCOHLEED_01467	1.83e-175	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
NCOHLEED_01468	0.0	-	-	-	T	-	-	-	histidine kinase DNA gyrase B
NCOHLEED_01469	1.95e-309	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NCOHLEED_01470	1.44e-109	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
NCOHLEED_01471	9.4e-257	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NCOHLEED_01472	2.78e-172	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NCOHLEED_01473	1.56e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NCOHLEED_01474	1.8e-50	fjo13	-	-	S	-	-	-	COG NOG19122 non supervised orthologous group
NCOHLEED_01475	8.27e-193	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
NCOHLEED_01476	4.14e-231	-	-	-	H	-	-	-	Methyltransferase domain protein
NCOHLEED_01477	2.75e-116	-	-	-	S	-	-	-	COG NOG29882 non supervised orthologous group
NCOHLEED_01478	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NCOHLEED_01479	1.15e-77	-	-	-	-	-	-	-	-
NCOHLEED_01480	0.0	scpC	2.8.3.18, 3.1.2.1	-	C	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0427 Acetyl-CoA hydrolase
NCOHLEED_01481	0.0	oprM_1	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
NCOHLEED_01482	0.0	bepE_1	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_01483	8.85e-267	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_01484	8.3e-224	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01485	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
NCOHLEED_01486	0.0	-	-	-	E	-	-	-	Peptidase family M1 domain
NCOHLEED_01487	8.71e-100	-	-	-	S	-	-	-	COG NOG29214 non supervised orthologous group
NCOHLEED_01488	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)
NCOHLEED_01489	2.02e-237	-	-	-	-	-	-	-	-
NCOHLEED_01490	3.81e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4907)
NCOHLEED_01491	3.22e-272	nanM	-	-	S	-	-	-	COG NOG23382 non supervised orthologous group
NCOHLEED_01492	0.0	-	-	-	S	-	-	-	COG NOG26034 non supervised orthologous group
NCOHLEED_01493	6.83e-294	-	-	-	I	-	-	-	COG NOG24984 non supervised orthologous group
NCOHLEED_01494	7.76e-181	-	-	-	K	-	-	-	COG3279 Response regulator of the LytR AlgR family
NCOHLEED_01496	1.74e-83	-	-	-	S	-	-	-	COG NOG29403 non supervised orthologous group
NCOHLEED_01497	1.21e-78	-	-	-	-	-	-	-	-
NCOHLEED_01498	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NCOHLEED_01499	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
NCOHLEED_01500	0.0	-	-	-	E	-	-	-	COG COG1305 Transglutaminase-like enzymes
NCOHLEED_01501	0.0	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3857)
NCOHLEED_01502	1.42e-137	rbr	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01503	0.0	sulP	-	-	P	ko:K03321	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01504	3.35e-211	nucA_1	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	Psort location Extracellular, score
NCOHLEED_01505	5.81e-123	-	-	-	S	-	-	-	COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NCOHLEED_01506	1.29e-188	-	-	-	C	-	-	-	radical SAM domain protein
NCOHLEED_01507	1.26e-91	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01508	6.81e-26	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
NCOHLEED_01509	0.0	-	-	-	L	-	-	-	Psort location OuterMembrane, score
NCOHLEED_01510	1.91e-144	-	-	-	S	-	-	-	COG NOG14459 non supervised orthologous group
NCOHLEED_01511	1.58e-188	-	-	-	S	-	-	-	COG4422 Bacteriophage protein gp37
NCOHLEED_01512	3.25e-225	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01513	1.99e-122	spoU	-	-	J	-	-	-	RNA methylase, SpoU family K00599
NCOHLEED_01514	7.61e-09	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NCOHLEED_01515	2.04e-224	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NCOHLEED_01516	2.87e-137	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NCOHLEED_01517	7.91e-216	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01518	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NCOHLEED_01519	1.08e-215	eamA	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01520	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4185)
NCOHLEED_01521	8.45e-140	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NCOHLEED_01522	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01523	0.0	-	-	-	S	ko:K07137	-	ko00000	FAD-dependent
NCOHLEED_01524	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NCOHLEED_01525	5.44e-127	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NCOHLEED_01526	3.02e-254	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
NCOHLEED_01527	0.0	thrA	1.1.1.3, 2.7.2.4	-	E	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NCOHLEED_01528	3.12e-314	-	5.4.2.12	-	G	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	homoserine kinase
NCOHLEED_01529	2.88e-316	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NCOHLEED_01531	1.29e-74	-	-	-	S	-	-	-	Plasmid stabilization system
NCOHLEED_01532	2.14e-29	-	-	-	-	-	-	-	-
NCOHLEED_01533	6.62e-218	-	-	-	EG	-	-	-	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NCOHLEED_01534	3.04e-162	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamine diphosphokinase
NCOHLEED_01535	5.22e-145	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NCOHLEED_01536	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	COG COG1629 Outer membrane receptor proteins, mostly Fe transport
NCOHLEED_01537	5.55e-168	mscS	-	-	M	ko:K03442	-	ko00000,ko02000	Small-conductance mechanosensitive channel
NCOHLEED_01538	1.86e-48	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01539	7.99e-120	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01540	3.27e-65	-	-	-	K	-	-	-	stress protein (general stress protein 26)
NCOHLEED_01541	1.7e-115	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01542	4.54e-95	-	-	-	J	-	-	-	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NCOHLEED_01543	2.67e-43	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
NCOHLEED_01544	1.82e-310	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
NCOHLEED_01545	6.97e-204	-	-	-	K	-	-	-	COG COG2207 AraC-type DNA-binding domain-containing proteins
NCOHLEED_01546	6.95e-193	-	-	-	M	-	-	-	COG NOG10981 non supervised orthologous group
NCOHLEED_01547	1.18e-30	-	-	-	S	-	-	-	RteC protein
NCOHLEED_01548	1.36e-50	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_01550	0.0	-	-	-	LO	-	-	-	Belongs to the peptidase S16 family
NCOHLEED_01551	1.32e-139	-	-	-	-	-	-	-	-
NCOHLEED_01552	6.61e-119	-	-	-	-	-	-	-	-
NCOHLEED_01553	9.74e-67	-	-	-	S	-	-	-	Helix-turn-helix domain
NCOHLEED_01554	8.71e-18	-	-	-	-	-	-	-	-
NCOHLEED_01555	9.1e-141	-	-	-	H	-	-	-	Methyltransferase domain
NCOHLEED_01556	1.16e-102	-	-	-	K	-	-	-	acetyltransferase
NCOHLEED_01557	2.35e-71	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
NCOHLEED_01558	1.54e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
NCOHLEED_01559	1.21e-63	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3876)
NCOHLEED_01560	1.48e-64	-	-	-	S	-	-	-	MerR HTH family regulatory protein
NCOHLEED_01561	2.39e-42	-	-	-	L	-	-	-	Phage integrase SAM-like domain
NCOHLEED_01562	1.77e-166	-	-	-	L	-	-	-	Phage integrase SAM-like domain
NCOHLEED_01563	1.86e-239	-	-	-	L	-	-	-	Arm DNA-binding domain
NCOHLEED_01564	5.92e-78	-	-	-	K	-	-	-	Arabinose-binding domain of AraC transcription regulator, N-term
NCOHLEED_01565	1.28e-32	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
NCOHLEED_01566	3.97e-36	-	-	-	-	-	-	-	-
NCOHLEED_01567	1.61e-34	-	-	-	S	-	-	-	RteC protein
NCOHLEED_01568	1.7e-72	-	-	-	S	-	-	-	Helix-turn-helix domain
NCOHLEED_01569	5.81e-113	-	-	-	-	-	-	-	-
NCOHLEED_01570	2.75e-143	-	-	-	-	-	-	-	-
NCOHLEED_01573	1.13e-74	-	-	-	S	-	-	-	AAA ATPase domain
NCOHLEED_01574	7.45e-255	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_01576	3.79e-252	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01577	2.08e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NCOHLEED_01578	2.68e-104	-	-	-	S	-	-	-	COG NOG23390 non supervised orthologous group
NCOHLEED_01579	3.54e-156	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NCOHLEED_01580	5.34e-155	-	-	-	S	-	-	-	Transposase
NCOHLEED_01581	4.47e-163	yjjG	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, TIGR02254 family
NCOHLEED_01582	3.39e-148	-	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
NCOHLEED_01583	0.0	-	-	-	K	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_01584	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_01586	3.44e-46	-	-	-	-	-	-	-	-
NCOHLEED_01588	4.12e-19	-	-	-	-	-	-	-	-
NCOHLEED_01589	2.35e-223	-	-	-	-	-	-	-	-
NCOHLEED_01590	0.0	-	-	-	S	-	-	-	Phage terminase large subunit
NCOHLEED_01591	1.67e-90	-	-	-	-	-	-	-	-
NCOHLEED_01592	3.09e-22	-	-	-	-	-	-	-	-
NCOHLEED_01593	5.97e-16	-	-	-	S	-	-	-	Histone H1-like protein Hc1
NCOHLEED_01594	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01595	8.17e-220	-	-	-	M	ko:K01993	-	ko00000	Auxiliary transport protein, membrane fusion protein
NCOHLEED_01596	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
NCOHLEED_01597	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NCOHLEED_01598	3.26e-253	-	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase
NCOHLEED_01599	8.34e-229	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NCOHLEED_01600	0.0	-	-	-	T	-	-	-	histidine kinase DNA gyrase B
NCOHLEED_01601	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
NCOHLEED_01602	1.29e-129	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01603	9.8e-179	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NCOHLEED_01604	9.68e-251	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NCOHLEED_01605	9.87e-122	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	bifunctional cobalamin biosynthesis protein
NCOHLEED_01607	4.26e-169	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
NCOHLEED_01608	0.0	-	-	-	E	ko:K03307	-	ko00000	alkaline phosphatase synthesis sensor protein phoR K07636
NCOHLEED_01609	2.29e-222	-	4.1.3.3, 4.2.1.41, 4.3.3.7	-	EM	ko:K01639,ko:K01707,ko:K01714	ko00053,ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapA family
NCOHLEED_01610	0.0	-	-	-	P	-	-	-	TonB dependent receptor
NCOHLEED_01611	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_01612	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat protein
NCOHLEED_01613	3.59e-173	-	-	-	S	-	-	-	Pfam:DUF1498
NCOHLEED_01614	3.51e-277	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
NCOHLEED_01615	4.09e-275	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NCOHLEED_01616	1.62e-135	tabA_1	-	-	G	-	-	-	COG COG2731 Beta-galactosidase, beta subunit
NCOHLEED_01617	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
NCOHLEED_01618	2.45e-71	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
NCOHLEED_01619	7.45e-49	-	-	-	-	-	-	-	-
NCOHLEED_01620	2.6e-37	-	-	-	-	-	-	-	-
NCOHLEED_01621	8.45e-288	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01622	2.39e-11	-	-	-	-	-	-	-	-
NCOHLEED_01623	4.15e-103	-	-	-	L	-	-	-	Bacterial DNA-binding protein
NCOHLEED_01624	1.35e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
NCOHLEED_01625	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
NCOHLEED_01626	1.51e-73	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01627	1.47e-116	-	-	-	K	-	-	-	Transcription termination antitermination factor NusG
NCOHLEED_01628	2.55e-19	-	-	-	-	-	-	-	-
NCOHLEED_01629	4.39e-83	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NCOHLEED_01630	8.07e-22	-	-	-	S	-	-	-	EpsG family
NCOHLEED_01631	1.94e-73	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_01632	1.69e-69	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCOHLEED_01634	1.02e-211	wbpP	5.1.3.2, 5.1.3.7	-	M	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
NCOHLEED_01635	6.28e-274	wbpO	1.1.1.136	-	M	ko:K02474,ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NCOHLEED_01636	2.18e-157	-	-	GT4	M	ko:K13004	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 1 family protein
NCOHLEED_01638	3.23e-60	-	-	-	-	-	-	-	-
NCOHLEED_01640	2.69e-165	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG COG0120 Ribose 5-phosphate isomerase
NCOHLEED_01641	0.0	ydaH	-	-	H	ko:K12942	-	ko00000	Psort location CytoplasmicMembrane, score
NCOHLEED_01642	4.64e-170	-	-	-	T	-	-	-	Response regulator receiver domain
NCOHLEED_01643	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_01644	7.31e-218	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG0462 Phosphoribosylpyrophosphate synthetase
NCOHLEED_01645	2.88e-36	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	phosphatidylinositol-4-phosphate 5-kinase family protein K00889
NCOHLEED_01646	9.35e-312	-	-	-	S	-	-	-	Peptidase M16 inactive domain
NCOHLEED_01647	1.62e-179	kdsB	2.7.7.38	-	H	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NCOHLEED_01648	2.88e-80	folK2	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	COG NOG22185 non supervised orthologous group
NCOHLEED_01649	0.0	mrcA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	COG5009 Membrane carboxypeptidase penicillin-binding protein
NCOHLEED_01651	9.76e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NCOHLEED_01652	5.07e-108	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Involved in allosteric regulation of aspartate carbamoyltransferase
NCOHLEED_01653	3.25e-141	-	-	-	S	-	-	-	COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NCOHLEED_01654	5.69e-187	-	-	-	S	-	-	-	COG NOG27381 non supervised orthologous group
NCOHLEED_01655	5.2e-312	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NCOHLEED_01656	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formyltetrahydrofolate synthetase
NCOHLEED_01657	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
NCOHLEED_01658	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_01659	5.02e-168	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NCOHLEED_01660	7.52e-198	-	-	-	-	-	-	-	-
NCOHLEED_01661	1.47e-142	-	-	-	S	-	-	-	COG NOG28927 non supervised orthologous group
NCOHLEED_01662	3.5e-219	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NCOHLEED_01663	0.0	uvrD2	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01664	1.02e-200	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NCOHLEED_01665	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NCOHLEED_01666	1.81e-128	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NCOHLEED_01667	1.59e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NCOHLEED_01668	3.35e-33	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NCOHLEED_01669	1.44e-253	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NCOHLEED_01670	1.02e-93	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01671	2.12e-53	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase, delta epsilon subunit, beta-sandwich domain protein
NCOHLEED_01672	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NCOHLEED_01673	1.42e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NCOHLEED_01674	1.39e-120	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
NCOHLEED_01675	3.26e-122	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
NCOHLEED_01676	4.13e-135	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
NCOHLEED_01677	3.27e-230	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
NCOHLEED_01678	5.54e-303	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
NCOHLEED_01679	4.99e-171	rnfB	-	-	C	ko:K03616	-	ko00000	electron transport complex, RnfABCDGE type, B subunit
NCOHLEED_01680	3.56e-94	-	-	-	T	ko:K03803	-	ko00000,ko03021	Positive regulator of sigma(E), RseC MucC
NCOHLEED_01681	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3078)
NCOHLEED_01682	1.69e-41	-	-	-	-	-	-	-	-
NCOHLEED_01683	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NCOHLEED_01684	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
NCOHLEED_01685	2.4e-312	-	-	-	V	-	-	-	MATE efflux family protein
NCOHLEED_01686	0.0	pop	-	-	EU	-	-	-	Peptidase, S9A B C family, catalytic domain protein
NCOHLEED_01687	3.42e-53	-	-	-	NT	-	-	-	type I restriction enzyme
NCOHLEED_01688	4.83e-102	wcgX	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01689	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_01690	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_01691	1.98e-117	nusG	-	-	K	ko:K02601,ko:K05785	-	ko00000,ko03000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NCOHLEED_01692	9.28e-317	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
NCOHLEED_01693	2.36e-219	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
NCOHLEED_01696	2.43e-264	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NCOHLEED_01697	5.56e-125	-	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase WecB/TagA/CpsF family
NCOHLEED_01698	1.02e-67	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
NCOHLEED_01699	1.16e-84	-	-	-	M	-	-	-	glycosyltransferase involved in LPS biosynthesis
NCOHLEED_01700	2.62e-93	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01701	4.86e-11	-	-	-	S	-	-	-	transferase hexapeptide repeat
NCOHLEED_01702	9.88e-54	-	-	-	-	-	-	-	-
NCOHLEED_01703	4.52e-138	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_01704	1.24e-19	-	-	-	H	-	-	-	Bacterial transferase hexapeptide (six repeats)
NCOHLEED_01705	2.65e-118	-	-	-	-	-	-	-	-
NCOHLEED_01706	3.72e-12	-	-	-	G	-	-	-	Acyltransferase family
NCOHLEED_01707	6.62e-118	-	-	-	-	-	-	-	-
NCOHLEED_01708	8.26e-66	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCOHLEED_01709	1.44e-43	-	-	-	C	-	-	-	hydrogenase beta subunit
NCOHLEED_01710	8.08e-116	-	-	-	C	-	-	-	coenzyme F420-reducing hydrogenase beta subunit
NCOHLEED_01711	8.75e-157	-	-	-	V	-	-	-	COG NOG25117 non supervised orthologous group
NCOHLEED_01712	4.86e-266	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NCOHLEED_01715	5.66e-137	-	-	-	GM	-	-	-	COG COG4464 Capsular polysaccharide biosynthesis protein
NCOHLEED_01716	0.0	-	-	-	DM	-	-	-	Chain length determinant protein
NCOHLEED_01717	1.01e-179	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	BexD CtrA VexA family polysaccharide export protein
NCOHLEED_01718	5.04e-258	wecA	-	-	M	-	-	-	UDP-N-acetylmuramyl pentapeptide phosphotransferase
NCOHLEED_01719	4.62e-131	-	-	-	K	-	-	-	Transcription termination factor nusG
NCOHLEED_01720	8.62e-293	-	-	-	L	-	-	-	COG NOG11942 non supervised orthologous group
NCOHLEED_01721	1.89e-155	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_01722	2.8e-206	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
NCOHLEED_01723	1.31e-75	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
NCOHLEED_01724	1.53e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
NCOHLEED_01725	2.47e-68	-	-	-	K	-	-	-	COG NOG34759 non supervised orthologous group
NCOHLEED_01726	3.6e-67	-	-	-	S	-	-	-	MerR HTH family regulatory protein
NCOHLEED_01727	2.79e-89	-	-	-	-	-	-	-	-
NCOHLEED_01728	9.7e-133	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01729	2.98e-147	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01730	1.33e-28	-	-	-	-	-	-	-	-
NCOHLEED_01731	3.86e-97	-	-	-	-	-	-	-	-
NCOHLEED_01732	1.07e-303	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_01733	7.97e-261	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_01734	7.48e-310	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
NCOHLEED_01735	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4434)
NCOHLEED_01736	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_01737	3.3e-166	-	4.2.2.5	PL8	N	ko:K19049	-	ko00000,ko01000	Polysaccharide lyase family 8, super-sandwich domain protein
NCOHLEED_01738	9.52e-264	-	-	-	Q	-	-	-	Domain of unknown function (DUF4838)
NCOHLEED_01739	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_01740	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_01741	5.48e-312	ce	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
NCOHLEED_01742	0.0	araE	-	-	P	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NCOHLEED_01743	2.68e-279	-	-	-	S	-	-	-	Domain of unknown function (DUF5109)
NCOHLEED_01744	3e-292	nagC	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_01745	9.48e-108	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
NCOHLEED_01746	6.59e-70	-	-	-	K	-	-	-	Transcription termination antitermination factor NusG
NCOHLEED_01747	6.33e-254	-	-	-	M	-	-	-	Chain length determinant protein
NCOHLEED_01748	0.0	kpsD	-	-	M	-	-	-	COG1596 Periplasmic protein involved in polysaccharide export
NCOHLEED_01749	0.0	wbpM	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
NCOHLEED_01751	1.32e-197	tolB3	-	-	U	-	-	-	WD40-like Beta Propeller Repeat
NCOHLEED_01752	2.48e-252	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NCOHLEED_01753	0.0	iorA	1.2.7.8	-	C	ko:K00179	-	br01601,ko00000,ko01000	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
NCOHLEED_01754	1.17e-132	iorB	1.2.7.8	-	C	ko:K00180	-	br01601,ko00000,ko01000	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
NCOHLEED_01755	1.15e-315	paaK	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NCOHLEED_01756	8.76e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NCOHLEED_01757	7.41e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NCOHLEED_01758	5.24e-128	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NCOHLEED_01759	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NCOHLEED_01760	1.51e-201	-	-	-	S	-	-	-	COG COG0457 FOG TPR repeat
NCOHLEED_01761	1.13e-126	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NCOHLEED_01762	6.87e-93	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NCOHLEED_01764	0.0	-	-	-	S	-	-	-	Phage-related minor tail protein
NCOHLEED_01765	2.7e-127	-	-	-	-	-	-	-	-
NCOHLEED_01766	2.62e-131	-	-	-	S	-	-	-	Predicted Peptidoglycan domain
NCOHLEED_01768	1.77e-05	-	-	-	M	-	-	-	COG3209 Rhs family protein
NCOHLEED_01769	4.3e-111	-	-	-	-	-	-	-	-
NCOHLEED_01770	1.9e-188	-	-	-	-	-	-	-	-
NCOHLEED_01771	3.65e-250	-	-	-	-	-	-	-	-
NCOHLEED_01772	0.0	-	-	-	-	-	-	-	-
NCOHLEED_01773	1.7e-63	-	-	-	-	-	-	-	-
NCOHLEED_01774	7.81e-262	-	-	-	-	-	-	-	-
NCOHLEED_01775	2.65e-118	-	-	-	-	-	-	-	-
NCOHLEED_01776	4.58e-127	-	-	-	S	-	-	-	Bacteriophage holin family
NCOHLEED_01777	2.07e-65	-	-	-	-	-	-	-	-
NCOHLEED_01778	1.93e-46	-	-	-	-	-	-	-	-
NCOHLEED_01779	2.05e-42	-	-	-	-	-	-	-	-
NCOHLEED_01780	1.56e-60	-	-	-	-	-	-	-	-
NCOHLEED_01781	1.47e-91	-	-	-	N	-	-	-	PFAM Uncharacterised protein family UPF0150
NCOHLEED_01782	1.38e-49	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
NCOHLEED_01783	8.83e-134	radC	-	-	L	ko:K03630	-	ko00000	COG2003 DNA repair
NCOHLEED_01784	1.58e-118	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01785	0.0	-	-	-	-	-	-	-	-
NCOHLEED_01786	7.03e-44	-	-	-	-	-	-	-	-
NCOHLEED_01787	2.01e-141	-	-	-	-	-	-	-	-
NCOHLEED_01788	3.81e-59	-	-	-	-	-	-	-	-
NCOHLEED_01789	1.73e-139	-	-	-	-	-	-	-	-
NCOHLEED_01790	1.06e-202	-	-	-	-	-	-	-	-
NCOHLEED_01791	2.09e-143	-	-	-	-	-	-	-	-
NCOHLEED_01792	7.71e-295	-	-	-	-	-	-	-	-
NCOHLEED_01793	2.52e-262	-	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp
NCOHLEED_01794	1.89e-115	-	-	-	-	-	-	-	-
NCOHLEED_01795	7.63e-143	-	-	-	-	-	-	-	-
NCOHLEED_01796	1.44e-72	-	-	-	-	-	-	-	-
NCOHLEED_01797	4.9e-74	-	-	-	-	-	-	-	-
NCOHLEED_01798	0.0	-	-	-	L	-	-	-	DNA primase
NCOHLEED_01801	1.68e-137	-	-	-	K	-	-	-	transcriptional regulator, LuxR family
NCOHLEED_01804	3e-17	-	-	-	-	-	-	-	-
NCOHLEED_01806	2.54e-288	-	-	-	S	-	-	-	Rhs element Vgr protein
NCOHLEED_01807	1.32e-223	-	-	-	S	-	-	-	Tetratricopeptide repeat
NCOHLEED_01808	3.69e-59	-	-	-	S	-	-	-	Immunity protein 17
NCOHLEED_01809	0.0	-	-	-	M	-	-	-	RHS repeat-associated core domain
NCOHLEED_01810	4.97e-70	-	-	-	S	-	-	-	SMI1 / KNR4 family
NCOHLEED_01811	0.00024	-	-	-	-	-	-	-	-
NCOHLEED_01812	6.8e-229	-	-	-	-	-	-	-	-
NCOHLEED_01813	1.93e-80	-	-	-	S	-	-	-	Bacterial toxin 44
NCOHLEED_01814	5.28e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4948)
NCOHLEED_01816	1.05e-61	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
NCOHLEED_01817	2.99e-70	-	-	-	-	-	-	-	-
NCOHLEED_01818	1.64e-124	-	-	-	H	-	-	-	Thiamine biosynthesis protein ThiF
NCOHLEED_01819	2.52e-101	-	-	-	K	-	-	-	Transcriptional regulator, LuxR family
NCOHLEED_01820	8.43e-71	-	-	-	-	-	-	-	-
NCOHLEED_01824	5.75e-137	-	-	-	C	-	-	-	Elongator protein 3, MiaB family, Radical SAM
NCOHLEED_01825	4.41e-251	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
NCOHLEED_01826	0.0	lktB	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NCOHLEED_01827	1.61e-95	-	-	-	-	-	-	-	-
NCOHLEED_01828	1.41e-31	-	-	-	-	-	-	-	-
NCOHLEED_01829	4.37e-58	-	-	-	-	-	-	-	-
NCOHLEED_01831	6.52e-100	-	-	-	-	-	-	-	-
NCOHLEED_01832	5.56e-59	-	-	-	-	-	-	-	-
NCOHLEED_01833	1.76e-160	-	-	-	L	-	-	-	Exonuclease
NCOHLEED_01834	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA-directed DNA polymerase
NCOHLEED_01835	5.18e-116	-	-	-	L	-	-	-	NUMOD4 motif
NCOHLEED_01836	1.72e-167	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
NCOHLEED_01837	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Bacterial DNA polymerase III alpha subunit
NCOHLEED_01838	4.5e-220	-	-	-	S	-	-	-	TOPRIM
NCOHLEED_01842	1.15e-234	-	-	-	E	-	-	-	Alpha/beta hydrolase family
NCOHLEED_01843	1.1e-50	-	-	-	S	-	-	-	COG NOG14112 non supervised orthologous group
NCOHLEED_01844	1.33e-162	-	-	-	S	ko:K02651	ko04112,map04112	ko00000,ko00001,ko02035,ko02044	COG NOG28004 non supervised orthologous group
NCOHLEED_01845	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	1,4-alpha-glucan branching enzyme
NCOHLEED_01846	4.94e-103	tabA_2	-	-	G	-	-	-	YhcH YjgK YiaL family protein
NCOHLEED_01847	3.58e-168	-	-	-	S	-	-	-	TIGR02453 family
NCOHLEED_01848	6.93e-49	-	-	-	-	-	-	-	-
NCOHLEED_01849	0.0	amyA2	-	-	G	-	-	-	Alpha amylase, catalytic domain
NCOHLEED_01850	3.86e-196	-	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
NCOHLEED_01851	3.86e-108	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_01852	3.36e-262	-	-	-	C	ko:K07138	-	ko00000	Fe-S center protein
NCOHLEED_01853	1.1e-150	-	-	-	J	-	-	-	Domain of unknown function (DUF4476)
NCOHLEED_01854	6.42e-198	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	COG0351 Hydroxymethylpyrimidine phosphomethylpyrimidine kinase
NCOHLEED_01855	7.28e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase TENI
NCOHLEED_01856	4.49e-167	moeZ	2.7.7.80, 2.8.1.11	-	H	ko:K21029,ko:K21147	ko04122,map04122	ko00000,ko00001,ko01000	involved in molybdopterin and thiamine biosynthesis family 2
NCOHLEED_01857	1.2e-283	thiH	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiH
NCOHLEED_01858	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NCOHLEED_01859	1.49e-181	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NCOHLEED_01860	4.03e-147	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NCOHLEED_01861	2.1e-39	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine biosynthesis protein ThiS
NCOHLEED_01862	1e-125	-	-	-	S	-	-	-	COG NOG35345 non supervised orthologous group
NCOHLEED_01863	3.19e-208	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
NCOHLEED_01864	8.54e-171	-	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01865	0.0	xylB_2	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Carbohydrate kinase, FGGY family protein
NCOHLEED_01866	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
NCOHLEED_01867	0.0	-	-	-	P	ko:K08138	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NCOHLEED_01868	0.0	ramA_2	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_01870	3.03e-188	-	-	-	-	-	-	-	-
NCOHLEED_01871	2.19e-217	-	2.1.1.72	-	L	ko:K00571,ko:K07319	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
NCOHLEED_01872	7.23e-124	-	-	-	-	-	-	-	-
NCOHLEED_01873	1.36e-209	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1
NCOHLEED_01874	2.08e-228	dam	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	COG0338 Site-specific DNA methylase
NCOHLEED_01875	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NCOHLEED_01876	5.93e-80	yocK	-	-	T	-	-	-	RNA polymerase-binding protein DksA
NCOHLEED_01877	5.74e-155	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NCOHLEED_01878	4.28e-224	-	-	-	S	-	-	-	COG NOG25370 non supervised orthologous group
NCOHLEED_01879	4.08e-82	-	-	-	-	-	-	-	-
NCOHLEED_01880	2.69e-179	aviRb	-	-	J	ko:K03437	-	ko00000,ko03016	RNA methyltransferase, TrmH
NCOHLEED_01881	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
NCOHLEED_01882	9.34e-130	-	-	-	S	-	-	-	COG NOG23374 non supervised orthologous group
NCOHLEED_01883	1.35e-75	-	-	-	S	ko:K15977	-	ko00000	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_01884	8.95e-313	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase, FAD-containing subunit
NCOHLEED_01885	4.11e-300	-	-	-	M	-	-	-	COG NOG06295 non supervised orthologous group
NCOHLEED_01886	0.0	eptA	-	-	S	-	-	-	lipid A phosphoethanolamine transferase, associated with polymyxin resistance
NCOHLEED_01887	3.3e-94	-	-	-	S	-	-	-	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
NCOHLEED_01888	0.0	-	-	-	S	ko:K07079	-	ko00000	4Fe-4S dicluster domain
NCOHLEED_01889	0.0	yccM	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01890	1.01e-145	otsB	2.4.1.15, 3.1.3.12	GT20	G	ko:K16055	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Trehalose-phosphatase
NCOHLEED_01892	2.16e-06	otsB	2.4.1.15, 3.1.3.12	GT20	G	ko:K16055	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Trehalose-phosphatase
NCOHLEED_01893	1.43e-129	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
NCOHLEED_01895	5.65e-196	vicX	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
NCOHLEED_01896	0.0	dtpD	-	-	E	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01897	2.71e-167	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
NCOHLEED_01898	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
NCOHLEED_01899	1.15e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
NCOHLEED_01900	0.0	uxaB	1.1.1.17, 1.1.1.58	-	C	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the mannitol dehydrogenase family. UxaB subfamily
NCOHLEED_01901	3.42e-124	-	-	-	T	-	-	-	FHA domain protein
NCOHLEED_01902	1.72e-266	-	-	-	S	-	-	-	Sporulation and cell division repeat protein
NCOHLEED_01903	0.0	-	-	-	S	-	-	-	Capsule assembly protein Wzi
NCOHLEED_01904	1.33e-128	rfbC	5.1.3.13	-	G	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NCOHLEED_01905	2.66e-315	ugd	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NCOHLEED_01906	9.87e-189	-	-	-	S	-	-	-	COG NOG26711 non supervised orthologous group
NCOHLEED_01907	2.29e-291	deaD	-	-	L	-	-	-	Belongs to the DEAD box helicase family
NCOHLEED_01908	1.49e-291	serB	3.1.3.3	-	ET	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	Psort location Cytoplasmic, score 8.96
NCOHLEED_01910	4.23e-102	-	-	-	O	-	-	-	COG NOG28456 non supervised orthologous group
NCOHLEED_01911	4.09e-271	lptG	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
NCOHLEED_01912	9.08e-283	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NCOHLEED_01913	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NCOHLEED_01914	4.17e-174	smtA	2.1.1.223	-	J	ko:K15460	-	ko00000,ko01000,ko03016	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NCOHLEED_01916	3.17e-212	zraS_1	-	-	T	-	-	-	GHKL domain
NCOHLEED_01917	4.55e-316	-	-	-	T	-	-	-	Sigma-54 interaction domain protein
NCOHLEED_01918	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
NCOHLEED_01919	3.27e-294	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
NCOHLEED_01920	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01921	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01922	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
NCOHLEED_01923	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NCOHLEED_01924	9.74e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
NCOHLEED_01925	5.2e-64	-	-	-	P	-	-	-	RyR domain
NCOHLEED_01927	0.0	-	-	-	P	-	-	-	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NCOHLEED_01928	2.3e-286	-	-	-	-	-	-	-	-
NCOHLEED_01929	5.45e-162	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01930	2.05e-186	loiP	-	-	M	ko:K07387	-	ko00000,ko01000,ko01002	COG0501 Zn-dependent protease with chaperone function
NCOHLEED_01931	1.17e-290	-	2.3.1.47	-	E	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Psort location Cytoplasmic, score
NCOHLEED_01932	2.66e-249	-	-	-	I	-	-	-	lipid kinase, YegS Rv2252 BmrU family
NCOHLEED_01933	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NCOHLEED_01934	5.49e-85	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_01935	6.07e-222	-	3.5.1.53	-	S	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	hydrolase, carbon-nitrogen family
NCOHLEED_01936	3.71e-279	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_01937	3.16e-125	-	-	-	S	-	-	-	protein containing a ferredoxin domain
NCOHLEED_01938	1.84e-145	-	3.6.3.21	-	V	ko:K02028,ko:K02068	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
NCOHLEED_01939	7.92e-180	-	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01940	2.25e-91	-	-	-	S	-	-	-	Domain of unknown function (DUF4891)
NCOHLEED_01941	1.58e-194	-	-	-	S	-	-	-	Domain of unknown function (DUF4377)
NCOHLEED_01942	3.09e-268	yqfO	-	-	C	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NCOHLEED_01943	1.89e-160	-	-	-	S	ko:K07164	-	ko00000	Zinc ribbon domain protein
NCOHLEED_01944	9.2e-289	-	-	-	S	-	-	-	non supervised orthologous group
NCOHLEED_01945	1.98e-189	-	-	-	S	-	-	-	COG NOG19137 non supervised orthologous group
NCOHLEED_01946	0.0	-	-	-	M	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
NCOHLEED_01947	1.29e-257	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_01948	0.0	bpeF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_01949	1.86e-212	per1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	COG2367 Beta-lactamase class A
NCOHLEED_01950	4.74e-106	-	-	-	V	-	-	-	COG NOG14438 non supervised orthologous group
NCOHLEED_01951	4.87e-189	amn	3.2.2.4	-	F	ko:K01241	ko00230,map00230	ko00000,ko00001,ko01000	COG COG0775 Nucleoside phosphorylase
NCOHLEED_01952	3.31e-239	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG1466 DNA polymerase III, delta subunit
NCOHLEED_01954	2.61e-105	-	-	-	K	-	-	-	COG NOG19093 non supervised orthologous group
NCOHLEED_01955	1.02e-190	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NCOHLEED_01956	8.21e-215	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NCOHLEED_01957	7.47e-163	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NCOHLEED_01958	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NCOHLEED_01959	4.74e-211	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NCOHLEED_01962	0.0	-	-	-	M	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
NCOHLEED_01963	0.0	htpG	-	-	T	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_01964	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
NCOHLEED_01965	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCOHLEED_01966	4.49e-279	-	-	-	S	-	-	-	tetratricopeptide repeat
NCOHLEED_01967	5.8e-270	uspA	-	-	T	-	-	-	COG0589 Universal stress protein UspA and related nucleotide-binding
NCOHLEED_01968	5.07e-61	-	-	-	S	-	-	-	COG NOG19094 non supervised orthologous group
NCOHLEED_01969	8.63e-190	batE	-	-	T	-	-	-	COG NOG22299 non supervised orthologous group
NCOHLEED_01970	0.0	batD	-	-	S	-	-	-	COG NOG06393 non supervised orthologous group
NCOHLEED_01971	9.73e-118	batC	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_01972	2.42e-238	batB	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
NCOHLEED_01973	2.9e-227	batA	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
NCOHLEED_01974	2.76e-248	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_01975	5.75e-208	-	-	-	S	-	-	-	protein (some members contain a von Willebrand factor type A (vWA) domain)
NCOHLEED_01976	1.01e-229	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NCOHLEED_01977	7.5e-243	-	-	-	L	-	-	-	Belongs to the bacterial histone-like protein family
NCOHLEED_01978	5.18e-55	himA	-	-	L	ko:K03530,ko:K04764	-	ko00000,ko03032,ko03036,ko03400	COG0776 Bacterial nucleoid DNA-binding protein
NCOHLEED_01979	0.0	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
NCOHLEED_01980	1.6e-220	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NCOHLEED_01981	5.37e-29	-	-	-	S	-	-	-	Domain of unknown function (DUF4295)
NCOHLEED_01982	3.49e-36	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NCOHLEED_01983	2.83e-57	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NCOHLEED_01984	1.97e-101	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NCOHLEED_01985	3.49e-246	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NCOHLEED_01986	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.49
NCOHLEED_01987	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NCOHLEED_01988	1.2e-203	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NCOHLEED_01989	5.16e-115	-	-	-	S	-	-	-	COG NOG29454 non supervised orthologous group
NCOHLEED_01990	4.89e-284	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NCOHLEED_01991	0.0	-	-	-	H	-	-	-	COG NOG06391 non supervised orthologous group
NCOHLEED_01992	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NCOHLEED_01993	3.75e-77	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score
NCOHLEED_01994	1.1e-214	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
NCOHLEED_01995	2.13e-190	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NCOHLEED_01996	1.03e-155	pgmB	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NCOHLEED_01997	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_01998	0.0	-	-	-	V	-	-	-	ABC transporter, permease protein
NCOHLEED_01999	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02000	1.28e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
NCOHLEED_02001	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02002	1.84e-206	-	-	-	S	-	-	-	Ser Thr phosphatase family protein
NCOHLEED_02003	2.72e-184	-	-	-	S	-	-	-	COG NOG27188 non supervised orthologous group
NCOHLEED_02004	0.0	zraR_2	-	-	T	-	-	-	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
NCOHLEED_02005	2.48e-310	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_02006	0.0	cvrA	-	-	P	ko:K11105	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02007	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
NCOHLEED_02008	0.0	susB	3.2.1.20, 3.2.1.3	GH31,GH97	G	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
NCOHLEED_02009	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
NCOHLEED_02010	0.0	-	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	COG NOG34737 non supervised orthologous group
NCOHLEED_02011	0.0	-	-	-	S	ko:K21571	-	ko00000	Outer membrane protein SusF_SusE
NCOHLEED_02012	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_02013	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02015	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02016	0.0	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_02017	1.29e-106	-	-	-	J	-	-	-	Threonine alanine tRNA ligase second additional domain protein
NCOHLEED_02018	2.01e-99	hsp20	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NCOHLEED_02019	1.78e-290	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02020	1.68e-255	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02021	5.03e-239	ybhS	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02022	0.0	-	-	-	G	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NCOHLEED_02023	1.44e-200	-	-	-	M	ko:K01993	-	ko00000	COG COG0845 Membrane-fusion protein
NCOHLEED_02024	1.34e-295	-	-	-	MU	-	-	-	COG NOG26656 non supervised orthologous group
NCOHLEED_02025	4.67e-216	-	-	-	K	-	-	-	Transcriptional regulator
NCOHLEED_02026	6.6e-129	ogt	2.1.1.63	-	H	ko:K00567,ko:K10778	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NCOHLEED_02027	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
NCOHLEED_02028	8.9e-274	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NCOHLEED_02029	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
NCOHLEED_02030	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NCOHLEED_02031	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Class II glutamine amidotransferase
NCOHLEED_02032	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related
NCOHLEED_02033	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase, glutamine-hydrolyzing
NCOHLEED_02034	3.15e-06	-	-	-	-	-	-	-	-
NCOHLEED_02035	2.34e-108	-	-	-	L	-	-	-	COG NOG29624 non supervised orthologous group
NCOHLEED_02036	1.15e-254	ugd	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NCOHLEED_02037	3.47e-210	-	-	-	M	-	-	-	GDP-mannose 4,6 dehydratase
NCOHLEED_02038	2.7e-267	pglE	-	-	E	-	-	-	Belongs to the DegT DnrJ EryC1 family
NCOHLEED_02039	3.86e-42	neuD	-	-	S	ko:K19429	-	ko00000,ko01000	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family
NCOHLEED_02040	1.08e-121	pglC	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02041	1.06e-144	-	-	GT4	M	ko:K13004	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase 4-like
NCOHLEED_02042	2.39e-108	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NCOHLEED_02044	6.52e-266	-	-	-	E	-	-	-	COG NOG11940 non supervised orthologous group
NCOHLEED_02046	7.14e-94	-	-	-	G	ko:K13663	-	ko00000,ko01000	nodulation
NCOHLEED_02047	1.62e-138	-	-	-	JM	-	-	-	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NCOHLEED_02048	5.09e-239	-	-	-	M	-	-	-	NAD dependent epimerase dehydratase family protein
NCOHLEED_02049	1.29e-176	-	-	-	T	-	-	-	COG COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases
NCOHLEED_02050	2.48e-275	aepY	-	-	EH	-	-	-	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NCOHLEED_02051	0.0	aepX	2.7.7.15, 2.7.7.39, 5.4.2.9	-	GIM	ko:K00968,ko:K00980,ko:K01841	ko00440,ko00564,ko01100,ko01120,ko01130,ko05231,map00440,map00564,map01100,map01120,map01130,map05231	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate phosphomutase
NCOHLEED_02052	1.78e-63	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_02054	2.06e-64	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NCOHLEED_02055	3.66e-238	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NCOHLEED_02056	1.33e-101	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NCOHLEED_02057	2.31e-97	-	-	-	L	-	-	-	Transposase IS66 family
NCOHLEED_02058	3.91e-34	-	-	-	L	-	-	-	Transposase IS66 family
NCOHLEED_02059	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02060	6.52e-103	-	-	-	S	-	-	-	UpxZ family of transcription anti-terminator antagonists
NCOHLEED_02061	8.73e-122	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02062	3.26e-76	-	-	-	-	-	-	-	-
NCOHLEED_02063	7.06e-81	-	-	-	S	-	-	-	WYL_2, Sm-like SH3 beta-barrel fold
NCOHLEED_02064	6.58e-161	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
NCOHLEED_02065	4.01e-186	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NCOHLEED_02066	1.83e-205	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NCOHLEED_02067	7.33e-313	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
NCOHLEED_02068	9.42e-174	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.52
NCOHLEED_02069	6.12e-76	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
NCOHLEED_02070	1.05e-306	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02071	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
NCOHLEED_02072	0.0	-	-	-	S	-	-	-	PS-10 peptidase S37
NCOHLEED_02073	1.79e-126	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02074	8.55e-17	-	-	-	-	-	-	-	-
NCOHLEED_02075	5.99e-289	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NCOHLEED_02076	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I
NCOHLEED_02077	2.91e-146	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Glutamine amidotransferase, class I
NCOHLEED_02078	1.78e-239	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NCOHLEED_02079	3.36e-184	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
NCOHLEED_02080	4.37e-153	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
NCOHLEED_02081	9.78e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NCOHLEED_02082	2.8e-255	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
NCOHLEED_02083	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4842)
NCOHLEED_02084	1.44e-79	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NCOHLEED_02085	2.68e-273	-	-	-	M	-	-	-	COG COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NCOHLEED_02086	7.02e-185	-	-	-	MU	-	-	-	COG NOG27134 non supervised orthologous group
NCOHLEED_02087	0.0	-	-	-	M	-	-	-	COG NOG36677 non supervised orthologous group
NCOHLEED_02088	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02089	8.89e-289	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02090	7.71e-278	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_02091	4.82e-297	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_02092	3.79e-251	-	-	-	F	-	-	-	Phosphoribosyl transferase domain
NCOHLEED_02093	1.34e-257	-	-	-	I	-	-	-	Acyltransferase family
NCOHLEED_02094	1.33e-39	-	-	-	-	-	-	-	-
NCOHLEED_02095	3.46e-241	-	-	-	S	-	-	-	Domain of unknown function (DUF4373)
NCOHLEED_02096	7.15e-51	-	3.6.4.12	-	L	ko:K17680	-	ko00000,ko01000,ko03029	Psort location Cytoplasmic, score 8.96
NCOHLEED_02097	2.44e-106	-	3.6.4.12	-	L	ko:K17680	-	ko00000,ko01000,ko03029	Psort location Cytoplasmic, score 8.96
NCOHLEED_02098	5.64e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
NCOHLEED_02099	1.63e-110	-	-	-	L	-	-	-	COG NOG31453 non supervised orthologous group
NCOHLEED_02100	3.62e-109	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02101	1.69e-284	-	-	-	S	-	-	-	Predicted AAA-ATPase
NCOHLEED_02102	1.98e-263	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCOHLEED_02103	3.22e-245	-	-	GT2	M	ko:K19354	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase like family 2
NCOHLEED_02104	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02105	1.82e-298	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
NCOHLEED_02106	2.39e-256	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCOHLEED_02107	3.12e-251	-	-	-	M	-	-	-	Glycosyltransferase
NCOHLEED_02108	0.0	-	-	-	E	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_02109	9.9e-285	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02110	1.02e-163	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
NCOHLEED_02111	2.36e-53	-	-	-	S	-	-	-	23S rRNA-intervening sequence protein
NCOHLEED_02112	1.37e-248	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
NCOHLEED_02113	6.38e-259	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
NCOHLEED_02114	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02115	4.75e-304	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
NCOHLEED_02116	1.61e-88	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NCOHLEED_02117	8.8e-264	-	-	-	O	-	-	-	Antioxidant, AhpC TSA family
NCOHLEED_02118	1.3e-237	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02119	0.0	nrdD	1.1.98.6	-	FK	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02120	8.86e-127	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NCOHLEED_02121	1.58e-315	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02122	8.37e-172	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02123	1.99e-183	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NCOHLEED_02124	2.68e-51	-	-	-	-	-	-	-	-
NCOHLEED_02125	4.56e-120	fldA	-	-	C	ko:K03839	-	ko00000	Low-potential electron donor to a number of redox enzymes
NCOHLEED_02126	0.0	glgP	2.4.1.1, 2.4.1.11, 2.4.1.8	GH65,GT3,GT35	G	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	COG0058 Glucan phosphorylase
NCOHLEED_02127	0.0	-	2.4.1.11	GT3	G	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	Starch synthase
NCOHLEED_02129	7.76e-89	ntpK	-	-	C	ko:K02124	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG COG0636 F0F1-type ATP synthase, subunit c Archaeal vacuolar-type H -ATPase, subunit K
NCOHLEED_02130	0.0	-	-	-	C	ko:K02123	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Belongs to the V-ATPase 116 kDa subunit family
NCOHLEED_02131	2.15e-132	-	-	-	C	ko:K02120	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Psort location Cytoplasmic, score 8.96
NCOHLEED_02132	0.0	ntpB	-	-	C	ko:K02118	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	ATP synthase alpha beta family, nucleotide-binding domain protein
NCOHLEED_02133	0.0	atpA	3.6.3.14, 3.6.3.15	-	C	ko:K02117	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NCOHLEED_02134	1.19e-195	-	-	-	C	-	-	-	Protein of unknown function (DUF2764)
NCOHLEED_02135	4.63e-104	-	-	-	C	ko:K02121	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG NOG11642 non supervised orthologous group
NCOHLEED_02136	2.84e-21	-	-	-	-	-	-	-	-
NCOHLEED_02137	2.52e-204	-	-	-	S	-	-	-	Putative beta-lactamase-inhibitor-like, PepSY-like
NCOHLEED_02138	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NCOHLEED_02139	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02140	5.22e-227	-	-	-	S	-	-	-	Core-2 I-Branching enzyme
NCOHLEED_02141	2.57e-220	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
NCOHLEED_02142	1.1e-257	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02143	0.0	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
NCOHLEED_02144	5.46e-181	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
NCOHLEED_02145	2.14e-173	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NCOHLEED_02146	3.61e-138	fklB	5.2.1.8	-	G	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
NCOHLEED_02147	8.11e-203	-	5.2.1.8	-	M	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
NCOHLEED_02148	2.06e-107	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	Transcriptional regulator, AsnC family
NCOHLEED_02149	1.54e-71	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02151	8.83e-19	-	-	-	-	-	-	-	-
NCOHLEED_02152	5.51e-69	-	-	-	-	-	-	-	-
NCOHLEED_02153	1.52e-08	-	-	-	L	ko:K03630	-	ko00000	DNA repair
NCOHLEED_02154	3.58e-66	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02155	4.48e-09	-	-	-	L	-	-	-	Transposase DDE domain
NCOHLEED_02156	7.11e-99	-	-	-	S	-	-	-	Lipocalin-like domain
NCOHLEED_02157	1.52e-151	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
NCOHLEED_02158	8.3e-77	-	-	-	-	-	-	-	-
NCOHLEED_02159	0.0	-	-	-	L	-	-	-	Phage integrase SAM-like domain
NCOHLEED_02160	1.47e-305	-	-	-	-	-	-	-	-
NCOHLEED_02161	3.08e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF3853)
NCOHLEED_02162	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
NCOHLEED_02163	2.89e-79	-	-	-	-	-	-	-	-
NCOHLEED_02164	4.13e-80	-	-	-	-	-	-	-	-
NCOHLEED_02165	2.53e-80	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02166	5.76e-287	-	-	-	U	-	-	-	relaxase mobilization nuclease domain protein
NCOHLEED_02167	6.23e-42	-	-	-	-	-	-	-	-
NCOHLEED_02171	1.05e-21	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02172	3.82e-94	-	-	-	S	-	-	-	Family of unknown function (DUF5457)
NCOHLEED_02173	0.0	-	-	-	S	-	-	-	oxidoreductase activity
NCOHLEED_02174	1.05e-190	-	-	-	S	-	-	-	Pkd domain
NCOHLEED_02175	1.53e-72	-	-	-	S	-	-	-	Family of unknown function (DUF5469)
NCOHLEED_02176	1.6e-78	-	-	-	-	-	-	-	-
NCOHLEED_02177	7.7e-211	-	-	-	S	-	-	-	type VI secretion protein
NCOHLEED_02178	2.68e-167	-	-	-	S	-	-	-	Family of unknown function (DUF5467)
NCOHLEED_02179	2.1e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02180	0.0	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
NCOHLEED_02181	5.33e-305	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02182	7.57e-71	-	-	-	S	-	-	-	Gene 25-like lysozyme
NCOHLEED_02183	5.62e-76	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02184	2.04e-273	-	-	-	S	-	-	-	this gene contains a nucleotide ambiguity which may be the result of a sequencing error
NCOHLEED_02187	3.6e-236	-	-	-	L	-	-	-	AAA ATPase domain
NCOHLEED_02189	4.37e-249	-	-	-	-	-	-	-	-
NCOHLEED_02190	0.0	-	-	-	G	-	-	-	cog cog3537
NCOHLEED_02191	1.3e-198	-	-	-	S	-	-	-	Domain of unknown function (DUF5040)
NCOHLEED_02192	0.0	-	-	-	S	ko:K09704	-	ko00000	Conserved protein
NCOHLEED_02193	3.68e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF3823)
NCOHLEED_02194	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	COG NOG30008 non supervised orthologous group
NCOHLEED_02195	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02196	3.07e-240	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
NCOHLEED_02197	2.35e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase
NCOHLEED_02198	2.23e-158	-	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related
NCOHLEED_02200	2.22e-232	-	-	-	S	-	-	-	VirE N-terminal domain
NCOHLEED_02201	5.22e-153	-	-	-	L	-	-	-	DNA photolyase activity
NCOHLEED_02203	0.0	-	3.2.1.45	GH116	G	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	ko00000,ko00001,ko01000	Pfam:GBA2_N
NCOHLEED_02204	0.0	-	-	-	-	-	-	-	-
NCOHLEED_02205	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4185)
NCOHLEED_02206	1.05e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4945)
NCOHLEED_02207	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_02208	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02209	2.22e-303	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
NCOHLEED_02210	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_02211	4.55e-303	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02212	4.22e-243	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02213	1.45e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF3853)
NCOHLEED_02214	3.04e-257	-	-	-	T	-	-	-	COG NOG25714 non supervised orthologous group
NCOHLEED_02215	2.97e-236	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02216	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02217	1.08e-142	-	-	-	S	-	-	-	COG NOG23408 non supervised orthologous group
NCOHLEED_02218	1.74e-105	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NCOHLEED_02219	5.38e-131	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NCOHLEED_02220	6.43e-203	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NCOHLEED_02221	1.14e-84	-	-	-	S	-	-	-	SnoaL-like polyketide cyclase
NCOHLEED_02222	7.03e-40	-	5.3.2.6	-	S	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Tautomerase enzyme
NCOHLEED_02223	1.52e-282	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_02224	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02225	3.07e-312	-	-	-	J	ko:K21572	-	ko00000,ko02000	COG NOG25454 non supervised orthologous group
NCOHLEED_02226	4.28e-294	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
NCOHLEED_02227	3.78e-271	-	-	-	S	-	-	-	ATPase domain predominantly from Archaea
NCOHLEED_02228	3.26e-226	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA-like C-terminal domain
NCOHLEED_02229	5.01e-75	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	domain protein
NCOHLEED_02230	1.88e-43	-	-	-	K	-	-	-	transcriptional regulator, y4mF family
NCOHLEED_02231	1.01e-76	-	-	-	-	-	-	-	-
NCOHLEED_02232	0.0	-	-	-	N	-	-	-	COG NOG14601 non supervised orthologous group
NCOHLEED_02234	7.69e-226	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_02235	1.53e-95	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
NCOHLEED_02236	3.49e-126	-	-	-	-	-	-	-	-
NCOHLEED_02237	0.0	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
NCOHLEED_02239	2.74e-112	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
NCOHLEED_02240	5.81e-300	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
NCOHLEED_02242	3.81e-83	-	-	-	-	-	-	-	-
NCOHLEED_02243	2.63e-56	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
NCOHLEED_02245	0.0	-	-	-	G	ko:K02429	-	ko00000,ko02000	L-fucose H symporter permease
NCOHLEED_02246	8.12e-304	-	-	-	-	-	-	-	-
NCOHLEED_02247	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NCOHLEED_02248	1.39e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.26
NCOHLEED_02249	5.57e-275	-	-	-	-	-	-	-	-
NCOHLEED_02250	0.0	-	-	-	N	-	-	-	COG NOG14601 non supervised orthologous group
NCOHLEED_02251	1.97e-34	-	-	-	-	-	-	-	-
NCOHLEED_02252	5.07e-143	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02254	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
NCOHLEED_02255	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NCOHLEED_02256	3.7e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NCOHLEED_02257	7.48e-189	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02258	1.39e-164	-	-	-	S	-	-	-	COG NOG19144 non supervised orthologous group
NCOHLEED_02259	0.0	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
NCOHLEED_02260	1.35e-196	-	-	-	-	-	-	-	-
NCOHLEED_02261	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NCOHLEED_02262	4.69e-235	-	-	-	M	-	-	-	Peptidase, M23
NCOHLEED_02263	2.39e-85	ycgE	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02264	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NCOHLEED_02265	0.0	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	Transglycosylase SLT domain
NCOHLEED_02266	5.9e-186	-	-	-	-	-	-	-	-
NCOHLEED_02267	1.51e-201	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NCOHLEED_02268	2.57e-174	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain
NCOHLEED_02269	1.31e-75	-	-	-	S	ko:K09793	-	ko00000	Psort location CytoplasmicMembrane, score
NCOHLEED_02270	0.0	-	-	-	E	-	-	-	Domain of Unknown Function (DUF1080)
NCOHLEED_02271	9.13e-192	surE	3.1.3.5	-	S	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NCOHLEED_02272	3.96e-275	lpxB	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NCOHLEED_02273	5.4e-183	-	-	-	S	-	-	-	COG NOG29298 non supervised orthologous group
NCOHLEED_02274	4.01e-199	cdsA	2.7.7.41	-	M	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NCOHLEED_02275	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NCOHLEED_02276	1.28e-82	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NCOHLEED_02278	2.88e-294	purH2	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
NCOHLEED_02279	0.0	-	-	-	A	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02280	5.98e-288	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
NCOHLEED_02281	8.08e-191	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NCOHLEED_02282	4.87e-215	-	-	-	S	ko:K07027	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02283	0.0	pepD_2	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Xaa-His dipeptidase
NCOHLEED_02285	0.0	-	-	-	S	-	-	-	COG2373 Large extracellular alpha-helical protein
NCOHLEED_02286	3.14e-253	-	-	-	S	-	-	-	COG NOG19146 non supervised orthologous group
NCOHLEED_02287	1.2e-262	argK	-	-	E	ko:K07588	-	ko00000,ko01000	Lao Ao transport system ATPase
NCOHLEED_02288	3.17e-129	-	-	-	T	-	-	-	Cyclic nucleotide-binding domain
NCOHLEED_02289	1.99e-206	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02290	1.07e-201	-	-	-	P	-	-	-	ATP-binding protein involved in virulence
NCOHLEED_02291	2.76e-246	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02292	1.11e-301	ybdG_2	-	-	M	ko:K16053	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
NCOHLEED_02293	3.4e-93	-	-	-	L	-	-	-	regulation of translation
NCOHLEED_02294	2.71e-279	-	-	-	N	-	-	-	COG NOG06100 non supervised orthologous group
NCOHLEED_02295	0.0	-	-	-	M	-	-	-	TonB-dependent receptor
NCOHLEED_02296	0.0	-	-	-	T	-	-	-	PAS domain S-box protein
NCOHLEED_02297	0.0	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCOHLEED_02298	0.0	nuoM	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	proton-translocating NADH-quinone oxidoreductase, chain M
NCOHLEED_02299	0.0	nuoL	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit
NCOHLEED_02300	1.01e-62	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCOHLEED_02301	3.57e-109	nuoJ	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG0839 NADH ubiquinone oxidoreductase subunit 6 (chain J)
NCOHLEED_02302	8.77e-104	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCOHLEED_02303	6.91e-259	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NCOHLEED_02304	0.0	nuoC	1.6.5.3	-	C	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCOHLEED_02305	2.37e-141	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCOHLEED_02306	2.07e-73	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NCOHLEED_02307	4.56e-87	-	-	-	-	-	-	-	-
NCOHLEED_02308	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02309	0.0	trkA	-	-	C	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems NAD-binding component
NCOHLEED_02310	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NCOHLEED_02312	7.55e-268	-	-	-	-	-	-	-	-
NCOHLEED_02313	5.39e-240	-	-	-	E	-	-	-	GSCFA family
NCOHLEED_02314	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NCOHLEED_02315	2.2e-25	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NCOHLEED_02316	1.62e-190	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NCOHLEED_02317	0.0	-	3.6.4.12	-	L	ko:K10742	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG COG1112 Superfamily I DNA and RNA helicases and helicase subunits
NCOHLEED_02318	0.0	exuT	-	-	G	ko:K08191	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02319	3.58e-237	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NCOHLEED_02320	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02321	4.96e-127	-	-	-	K	ko:K03088	-	ko00000,ko03021	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NCOHLEED_02322	2.32e-279	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
NCOHLEED_02323	0.0	-	-	-	P	-	-	-	non supervised orthologous group
NCOHLEED_02324	0.0	-	-	-	J	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_02325	2.09e-289	-	-	-	T	-	-	-	COG COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases
NCOHLEED_02326	2.41e-155	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
NCOHLEED_02328	7.82e-204	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NCOHLEED_02329	7.18e-170	rsmI_1	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Psort location Cytoplasmic, score 8.96
NCOHLEED_02330	7.86e-266	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02331	1.13e-216	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NCOHLEED_02332	0.0	dpp	3.4.14.5	-	EU	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
NCOHLEED_02333	1.57e-187	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02334	6.63e-259	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02335	6.96e-240	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_02336	1.5e-229	-	-	-	S	ko:K07139	-	ko00000	radical SAM protein, TIGR01212 family
NCOHLEED_02337	1.07e-298	fprA	1.6.3.4	-	C	ko:K22405	-	ko00000,ko01000	anaerobic nitric oxide reductase flavorubredoxin
NCOHLEED_02338	1.4e-194	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NCOHLEED_02339	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02340	6.5e-134	-	-	-	-	-	-	-	-
NCOHLEED_02341	2.89e-29	-	-	-	S	-	-	-	NVEALA protein
NCOHLEED_02342	2.26e-243	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
NCOHLEED_02343	8.21e-17	-	-	-	S	-	-	-	NVEALA protein
NCOHLEED_02345	1.05e-110	-	-	-	M	-	-	-	TolB-like 6-blade propeller-like
NCOHLEED_02346	2.87e-79	-	-	-	S	-	-	-	protein BT4048 SWALL AAO79153 (EMBL AE016943) (373 aa) fasta scores E()
NCOHLEED_02347	1e-216	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NCOHLEED_02348	0.0	-	-	-	E	-	-	-	non supervised orthologous group
NCOHLEED_02349	0.0	-	-	-	E	-	-	-	non supervised orthologous group
NCOHLEED_02350	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02351	2.18e-249	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_02352	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_02353	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
NCOHLEED_02354	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_02355	1.71e-159	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02356	4.33e-36	-	-	-	-	-	-	-	-
NCOHLEED_02358	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_02359	7.65e-101	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
NCOHLEED_02360	5.15e-262	-	-	-	M	-	-	-	N-terminal domain of galactosyltransferase
NCOHLEED_02361	4.01e-258	-	-	-	-	-	-	-	-
NCOHLEED_02363	4.26e-307	-	-	-	S	-	-	-	Domain of unknown function (DUF4934)
NCOHLEED_02364	0.0	-	-	-	C	ko:K06871	-	ko00000	4Fe-4S single cluster domain
NCOHLEED_02365	1.37e-313	-	-	-	S	-	-	-	radical SAM domain protein
NCOHLEED_02366	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NCOHLEED_02367	1.89e-294	-	-	-	V	-	-	-	HlyD family secretion protein
NCOHLEED_02368	4.3e-208	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
NCOHLEED_02369	9.75e-301	-	-	-	S	-	-	-	protein BT3056 SWALL AAO78162 (EMBL AE016938) (409 aa) fasta scores E()
NCOHLEED_02370	7.42e-232	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02371	5.32e-148	yciO	-	-	J	-	-	-	Belongs to the SUA5 family
NCOHLEED_02372	0.0	-	-	-	L	-	-	-	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
NCOHLEED_02373	4.91e-194	-	-	-	S	-	-	-	of the HAD superfamily
NCOHLEED_02374	2.35e-211	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02375	4.55e-149	-	-	-	S	ko:K07052	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02376	1.74e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NCOHLEED_02377	0.0	-	-	-	KT	-	-	-	response regulator
NCOHLEED_02378	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
NCOHLEED_02379	3e-189	celA	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Cellulase (glycosyl hydrolase family 5)
NCOHLEED_02380	1.21e-309	-	-	-	T	-	-	-	COG COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain
NCOHLEED_02381	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02382	1.05e-284	-	-	-	S	-	-	-	COG NOG26077 non supervised orthologous group
NCOHLEED_02383	2.43e-184	-	-	-	-	-	-	-	-
NCOHLEED_02384	0.0	bglB_3	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
NCOHLEED_02385	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 C-terminal domain protein
NCOHLEED_02386	1.52e-213	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
NCOHLEED_02387	0.0	-	-	-	O	ko:K06889	-	ko00000	COG COG1073 Hydrolases of the alpha beta superfamily
NCOHLEED_02388	1.63e-39	-	-	-	S	-	-	-	COG NOG17292 non supervised orthologous group
NCOHLEED_02389	2.76e-20	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02390	4.51e-56	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02391	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score
NCOHLEED_02392	5.04e-279	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.97
NCOHLEED_02393	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
NCOHLEED_02394	9.04e-299	-	-	-	P	-	-	-	Psort location OuterMembrane, score
NCOHLEED_02395	5.43e-167	-	-	-	-	-	-	-	-
NCOHLEED_02396	1.52e-285	-	-	-	J	-	-	-	endoribonuclease L-PSP
NCOHLEED_02397	0.0	ccsA	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02398	1.3e-139	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NCOHLEED_02399	3.99e-167	-	-	-	D	ko:K07322	-	ko00000	Hemerythrin HHE cation binding domain protein
NCOHLEED_02400	6.16e-81	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
NCOHLEED_02401	0.0	-	-	-	CO	-	-	-	COG NOG24773 non supervised orthologous group
NCOHLEED_02402	0.0	-	-	-	KT	-	-	-	COG NOG25147 non supervised orthologous group
NCOHLEED_02403	2.49e-181	-	-	-	CO	-	-	-	AhpC TSA family
NCOHLEED_02404	3.91e-309	-	-	-	M	-	-	-	Linear amide C-N hydrolases, choloylglycine hydrolase family
NCOHLEED_02405	4.11e-223	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NCOHLEED_02406	4.45e-128	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02407	4.85e-148	lpxA	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NCOHLEED_02408	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
NCOHLEED_02409	1.28e-161	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NCOHLEED_02410	3.53e-294	-	-	-	S	ko:K06885	-	ko00000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02411	1.99e-197	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
NCOHLEED_02412	2.25e-264	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NCOHLEED_02413	4.54e-285	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_02414	1.56e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NCOHLEED_02415	2.62e-190	-	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
NCOHLEED_02416	7.1e-255	-	-	-	S	ko:K06889	-	ko00000	of the alpha beta superfamily
NCOHLEED_02417	3.16e-180	aroE	1.1.1.25	-	C	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	COG0169 Shikimate 5-dehydrogenase
NCOHLEED_02418	1.75e-134	-	-	-	-	-	-	-	-
NCOHLEED_02419	3.83e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NCOHLEED_02420	8.35e-229	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NCOHLEED_02421	6.28e-225	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein
NCOHLEED_02422	3.84e-152	nlpD_2	-	-	M	-	-	-	COG COG0739 Membrane proteins related to metalloendopeptidases
NCOHLEED_02423	3.42e-157	-	-	-	S	-	-	-	B3 4 domain protein
NCOHLEED_02424	3.21e-207	-	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
NCOHLEED_02425	3.21e-287	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NCOHLEED_02426	1.08e-131	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NCOHLEED_02427	1.44e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NCOHLEED_02428	0.0	-	-	-	P	ko:K03305	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02429	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NCOHLEED_02430	1.96e-137	-	-	-	S	-	-	-	protein conserved in bacteria
NCOHLEED_02431	9.77e-160	-	-	-	S	-	-	-	COG NOG26960 non supervised orthologous group
NCOHLEED_02432	3.87e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NCOHLEED_02433	5.3e-209	-	-	-	EG	ko:K08978	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02434	7.45e-111	msrC	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02435	1.7e-156	-	-	-	S	-	-	-	COG NOG19149 non supervised orthologous group
NCOHLEED_02436	8.13e-207	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02437	1.79e-214	rhaR_1	-	-	K	-	-	-	transcriptional regulator (AraC family)
NCOHLEED_02438	2.36e-141	-	5.3.1.9	-	G	ko:K06859	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucose-6-phosphate isomerase (GPI)
NCOHLEED_02439	2.24e-236	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NCOHLEED_02440	0.0	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02441	3.46e-204	-	5.3.1.9	-	G	ko:K06859	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucose-6-phosphate isomerase (GPI)
NCOHLEED_02442	0.0	araE	-	-	P	ko:K02100	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NCOHLEED_02443	0.0	-	3.2.1.45	GH116	G	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term
NCOHLEED_02444	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02445	0.0	-	-	-	K	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_02446	1.83e-300	-	-	-	G	-	-	-	BNR repeat-like domain
NCOHLEED_02447	8.9e-302	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
NCOHLEED_02448	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
NCOHLEED_02449	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Chitobiase/beta-hexosaminidase C-terminal domain
NCOHLEED_02450	0.0	-	3.2.1.45	GH116	G	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	ko00000,ko00001,ko01000	Pfam:GBA2_N
NCOHLEED_02451	2.37e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
NCOHLEED_02452	5.32e-287	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02453	7.37e-133	-	-	-	T	-	-	-	Cyclic nucleotide-binding domain protein
NCOHLEED_02454	5.33e-63	-	-	-	-	-	-	-	-
NCOHLEED_02457	9.28e-118	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NCOHLEED_02458	4.51e-140	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_02459	2.69e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NCOHLEED_02460	1.27e-60	-	-	-	S	-	-	-	COG NOG38282 non supervised orthologous group
NCOHLEED_02461	2.38e-190	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NCOHLEED_02462	9.5e-114	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02463	0.0	ctp	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NCOHLEED_02464	1.45e-104	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
NCOHLEED_02465	1.99e-111	-	-	-	S	-	-	-	COG NOG30732 non supervised orthologous group
NCOHLEED_02466	0.0	dcp	3.4.15.5, 3.4.24.70	-	E	ko:K01284,ko:K01414	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
NCOHLEED_02467	6.04e-221	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NCOHLEED_02468	2.51e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NCOHLEED_02470	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NCOHLEED_02471	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Psort location Cytoplasmic, score
NCOHLEED_02472	2.31e-163	-	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related
NCOHLEED_02473	2.3e-150	-	-	-	K	-	-	-	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCOHLEED_02474	2e-144	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02476	0.0	-	-	-	G	-	-	-	glycogen debranching enzyme, archaeal type
NCOHLEED_02477	0.0	gmhA	2.4.1.346	GT4	M	ko:K13668	-	ko00000,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NCOHLEED_02478	0.0	amyA	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 57 family
NCOHLEED_02479	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4270)
NCOHLEED_02480	7.53e-201	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Starch synthase, catalytic domain
NCOHLEED_02481	2.73e-204	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NCOHLEED_02482	1.45e-78	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NCOHLEED_02483	0.0	-	-	-	M	-	-	-	Peptidase family S41
NCOHLEED_02484	0.0	gltA	1.3.1.1, 1.4.1.13, 1.4.1.14	-	C	ko:K00266,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.97
NCOHLEED_02485	0.0	-	-	-	H	-	-	-	Outer membrane protein beta-barrel family
NCOHLEED_02486	1e-248	-	-	-	T	-	-	-	Histidine kinase
NCOHLEED_02487	2.6e-167	-	-	-	K	-	-	-	LytTr DNA-binding domain
NCOHLEED_02488	2.87e-308	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
NCOHLEED_02489	8.63e-58	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NCOHLEED_02490	4.06e-68	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NCOHLEED_02491	0.0	ppaX	3.1.3.18	-	V	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
NCOHLEED_02492	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
NCOHLEED_02493	1.35e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog
NCOHLEED_02494	6.34e-233	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
NCOHLEED_02495	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
NCOHLEED_02496	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02497	0.0	-	-	-	H	-	-	-	Susd and RagB outer membrane lipoprotein
NCOHLEED_02498	1.03e-241	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
NCOHLEED_02499	9.04e-278	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
NCOHLEED_02500	0.0	-	-	-	G	-	-	-	Psort location Extracellular, score
NCOHLEED_02502	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
NCOHLEED_02503	2.75e-294	ampG	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02504	3.64e-253	-	2.4.1.319, 2.4.1.320	-	G	ko:K18785	-	ko00000,ko01000	glycosylase
NCOHLEED_02505	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
NCOHLEED_02506	0.0	-	-	-	T	-	-	-	COG COG0642 Signal transduction histidine kinase
NCOHLEED_02507	7.47e-202	-	-	-	S	ko:K09973	-	ko00000	GumN protein
NCOHLEED_02508	1.25e-118	mepS	3.4.17.13	-	M	ko:K13694	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
NCOHLEED_02509	2.96e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system ATPase component
NCOHLEED_02510	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02511	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Belongs to the peptidase M16 family
NCOHLEED_02512	6.11e-187	kdsA	2.5.1.55	-	H	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the KdsA family
NCOHLEED_02513	2.8e-229	-	-	-	I	-	-	-	lipid kinase, YegS Rv2252 BmrU family
NCOHLEED_02514	3.25e-222	miaA2	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NCOHLEED_02516	1.74e-284	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
NCOHLEED_02517	1.26e-156	-	-	-	S	ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide repeat protein
NCOHLEED_02518	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	COG COG3973 Superfamily I DNA and RNA helicases
NCOHLEED_02519	2.1e-140	-	-	-	S	-	-	-	COG NOG23385 non supervised orthologous group
NCOHLEED_02520	6.38e-183	-	-	-	K	-	-	-	COG NOG38984 non supervised orthologous group
NCOHLEED_02521	2.64e-108	-	-	-	S	-	-	-	COG NOG17277 non supervised orthologous group
NCOHLEED_02522	2.01e-74	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02523	5.58e-219	-	-	-	L	-	-	-	COG COG3464 Transposase and inactivated derivatives
NCOHLEED_02525	3.25e-251	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NCOHLEED_02526	2.06e-191	deoD	2.4.2.1	-	F	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NCOHLEED_02527	3.04e-281	lpxK	2.7.1.130	-	F	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
NCOHLEED_02528	0.0	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA, 67K type
NCOHLEED_02529	6.95e-192	-	-	-	S	-	-	-	Domain of unknown function (DUF3869)
NCOHLEED_02530	2.04e-225	-	-	-	-	-	-	-	-
NCOHLEED_02531	2.49e-277	-	-	-	L	-	-	-	Arm DNA-binding domain
NCOHLEED_02533	2.72e-313	-	-	-	-	-	-	-	-
NCOHLEED_02534	3.3e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF3869)
NCOHLEED_02535	6.94e-110	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCOHLEED_02536	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NCOHLEED_02537	0.0	-	-	-	D	-	-	-	Domain of unknown function
NCOHLEED_02538	2.67e-272	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_02539	1.07e-58	-	-	-	-	-	-	-	-
NCOHLEED_02540	2.86e-39	-	-	-	-	-	-	-	-
NCOHLEED_02541	2.4e-41	-	-	-	-	-	-	-	-
NCOHLEED_02543	2.29e-34	-	-	-	-	-	-	-	-
NCOHLEED_02547	4.64e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF5053)
NCOHLEED_02549	0.0	-	-	-	-	-	-	-	-
NCOHLEED_02550	1.33e-312	-	-	-	S	-	-	-	Rhs element Vgr protein
NCOHLEED_02554	1.98e-79	-	-	-	-	-	-	-	-
NCOHLEED_02555	0.0	-	-	-	DN	-	-	-	COG NOG14601 non supervised orthologous group
NCOHLEED_02556	7.01e-114	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_02560	3.09e-178	-	-	-	S	-	-	-	NigD-like N-terminal OB domain
NCOHLEED_02561	1.56e-120	-	-	-	L	-	-	-	DNA-binding protein
NCOHLEED_02562	3.55e-95	-	-	-	S	-	-	-	YjbR
NCOHLEED_02563	6.39e-260	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NCOHLEED_02564	3.31e-89	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02565	3e-44	-	-	-	H	-	-	-	Psort location OuterMembrane, score
NCOHLEED_02566	4.51e-207	-	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase family
NCOHLEED_02567	4.46e-227	-	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NCOHLEED_02568	0.0	-	-	-	NU	-	-	-	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
NCOHLEED_02569	2.38e-83	-	-	-	-	-	-	-	-
NCOHLEED_02570	7.08e-74	-	-	-	S	-	-	-	IS66 Orf2 like protein
NCOHLEED_02571	0.0	-	-	-	L	-	-	-	Transposase IS66 family
NCOHLEED_02572	0.0	-	-	-	L	-	-	-	Integrase core domain
NCOHLEED_02573	7.14e-182	-	-	-	L	-	-	-	IstB-like ATP binding protein
NCOHLEED_02574	1.12e-210	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NCOHLEED_02575	1.41e-288	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NCOHLEED_02576	7.64e-220	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
NCOHLEED_02577	2.13e-245	-	-	-	S	ko:K07098	-	ko00000	Ser Thr phosphatase family protein
NCOHLEED_02578	0.0	ppsA	-	-	GKT	-	-	-	Pyruvate phosphate dikinase, PEP pyruvate binding domain
NCOHLEED_02579	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_02580	1.14e-226	-	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
NCOHLEED_02581	9.72e-178	-	3.5.99.6	-	G	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko01000	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase
NCOHLEED_02582	1.92e-300	gluP	-	-	G	ko:K02429	-	ko00000,ko02000	Transporter, major facilitator family protein
NCOHLEED_02583	0.0	-	3.2.1.14	GH18	G	ko:K01183,ko:K09992	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 18 family
NCOHLEED_02584	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02585	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_02586	1.75e-205	-	-	-	S	-	-	-	Trehalose utilisation
NCOHLEED_02587	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 9
NCOHLEED_02588	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02589	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02590	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_02591	1.09e-298	-	-	-	S	-	-	-	Starch-binding module 26
NCOHLEED_02593	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme, glucanotransferase domain
NCOHLEED_02594	0.0	-	3.2.1.20, 3.2.1.3	GH31,GH97	G	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
NCOHLEED_02595	0.0	gdh	1.4.1.4	-	C	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NCOHLEED_02596	5.91e-280	pepQ	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	xaa-pro dipeptidase K01271
NCOHLEED_02597	1.04e-251	-	-	-	S	-	-	-	COG NOG26961 non supervised orthologous group
NCOHLEED_02598	5.47e-130	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NCOHLEED_02599	4.41e-217	ddh	1.4.1.16	-	E	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NCOHLEED_02600	0.0	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NCOHLEED_02601	3.64e-271	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NCOHLEED_02602	1.98e-197	nlpD_1	-	-	M	-	-	-	Peptidase, M23 family
NCOHLEED_02603	1.1e-125	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NCOHLEED_02604	2.59e-312	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NCOHLEED_02605	1.35e-142	-	-	-	S	-	-	-	COG NOG11645 non supervised orthologous group
NCOHLEED_02606	6.55e-155	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
NCOHLEED_02607	1.3e-186	-	-	-	S	-	-	-	stress-induced protein
NCOHLEED_02608	9.66e-129	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NCOHLEED_02609	1.96e-49	-	-	-	-	-	-	-	-
NCOHLEED_02610	1.43e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NCOHLEED_02611	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
NCOHLEED_02612	9.69e-273	cobW	-	-	S	-	-	-	CobW P47K family protein
NCOHLEED_02613	0.0	gdhA	1.4.1.4	-	C	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NCOHLEED_02614	0.0	maeB	1.1.1.38, 1.1.1.40	-	C	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_02615	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
NCOHLEED_02616	0.0	metZ	2.5.1.49	-	E	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
NCOHLEED_02617	5.31e-242	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
NCOHLEED_02618	1.97e-199	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02619	4.68e-209	-	-	-	K	ko:K13652	-	ko00000,ko03000	methylphosphotriester-DNA alkyltransferase (AraC XylS family)
NCOHLEED_02620	8.41e-174	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02621	1.3e-165	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NCOHLEED_02622	8.09e-80	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NCOHLEED_02623	1.42e-62	-	-	-	-	-	-	-	-
NCOHLEED_02624	1.42e-57	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NCOHLEED_02625	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02626	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
NCOHLEED_02627	0.0	-	-	-	KT	-	-	-	Y_Y_Y domain
NCOHLEED_02628	3.18e-282	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02629	8.75e-152	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system ATPase component
NCOHLEED_02630	0.0	-	-	-	S	-	-	-	COG NOG26882 non supervised orthologous group
NCOHLEED_02631	2.5e-169	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NCOHLEED_02632	2.34e-128	-	-	-	S	ko:K08999	-	ko00000	Conserved protein
NCOHLEED_02633	1.24e-299	nupG	-	-	G	ko:K03289,ko:K11537	-	ko00000,ko02000	transport of nucleosides, permease protein K03289
NCOHLEED_02634	2.56e-293	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	SAM-dependent
NCOHLEED_02635	2.24e-146	rnd	-	-	L	-	-	-	3'-5' exonuclease
NCOHLEED_02636	2.57e-127	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02637	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
NCOHLEED_02638	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
NCOHLEED_02639	3.95e-23	-	-	-	S	-	-	-	COG3943 Virulence protein
NCOHLEED_02642	1.77e-05	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
NCOHLEED_02643	1.03e-140	-	-	-	L	-	-	-	regulation of translation
NCOHLEED_02644	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related
NCOHLEED_02645	2.41e-150	lolA	-	-	M	ko:K03634	-	ko00000	COG NOG19151 non supervised orthologous group
NCOHLEED_02646	7.12e-227	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NCOHLEED_02647	2.45e-157	-	-	-	K	ko:K21556	-	ko00000,ko03000	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCOHLEED_02648	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
NCOHLEED_02649	0.0	-	-	-	S	-	-	-	COG NOG25960 non supervised orthologous group
NCOHLEED_02650	1.34e-195	-	2.7.1.33	-	H	ko:K09680	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenate kinase
NCOHLEED_02651	1.25e-203	-	-	-	I	-	-	-	COG0657 Esterase lipase
NCOHLEED_02652	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
NCOHLEED_02653	4.28e-181	-	-	-	-	-	-	-	-
NCOHLEED_02654	1.43e-220	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NCOHLEED_02655	1.49e-126	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NCOHLEED_02656	2.46e-81	-	-	-	S	-	-	-	COG NOG23405 non supervised orthologous group
NCOHLEED_02657	7.97e-111	-	-	-	S	-	-	-	COG NOG28735 non supervised orthologous group
NCOHLEED_02658	1.94e-191	mazG	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02659	9.57e-247	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02660	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NCOHLEED_02661	0.0	-	-	-	G	-	-	-	Cellulase N-terminal ig-like domain
NCOHLEED_02662	9.13e-240	-	-	-	S	-	-	-	Trehalose utilisation
NCOHLEED_02663	3.78e-117	-	-	-	-	-	-	-	-
NCOHLEED_02664	1.6e-134	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
NCOHLEED_02665	2.19e-230	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
NCOHLEED_02666	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02667	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	COG NOG30008 non supervised orthologous group
NCOHLEED_02668	1.69e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF3823)
NCOHLEED_02669	0.0	-	3.1.1.17	-	G	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	ko00000,ko00001,ko00002,ko01000,ko04147	SMP-30/Gluconolaconase/LRE-like region
NCOHLEED_02670	0.0	-	-	-	G	-	-	-	SMP-30/Gluconolaconase/LRE-like region
NCOHLEED_02671	2.17e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02672	1.84e-261	-	-	-	S	-	-	-	COG NOG26558 non supervised orthologous group
NCOHLEED_02673	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NCOHLEED_02674	0.0	pafA	-	-	P	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
NCOHLEED_02675	2.6e-270	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02676	5.23e-172	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NCOHLEED_02677	2.35e-305	-	-	-	I	-	-	-	Psort location OuterMembrane, score
NCOHLEED_02678	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_02679	7.23e-148	-	-	-	S	-	-	-	Lipopolysaccharide-assembly, LptC-related
NCOHLEED_02680	2.26e-286	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
NCOHLEED_02681	0.0	ppiD	5.2.1.8	-	O	ko:K01802,ko:K03770	-	ko00000,ko01000,ko03110	COG NOG26630 non supervised orthologous group
NCOHLEED_02682	9.99e-250	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NCOHLEED_02683	4.31e-257	-	-	-	L	-	-	-	COG NOG11654 non supervised orthologous group
NCOHLEED_02684	2.52e-263	pdxA	1.1.1.262	-	C	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the PdxA family
NCOHLEED_02685	7.69e-293	fhlA	-	-	K	-	-	-	Sigma-54 interaction domain protein
NCOHLEED_02686	5.68e-117	lptE	-	-	S	-	-	-	COG NOG14471 non supervised orthologous group
NCOHLEED_02687	1.6e-173	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02688	1.85e-64	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
NCOHLEED_02689	0.0	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NCOHLEED_02690	4.66e-84	pqqD	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02691	2.63e-244	-	-	-	S	-	-	-	COG NOG25792 non supervised orthologous group
NCOHLEED_02692	6.35e-278	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG2706 3-carboxymuconate cyclase
NCOHLEED_02693	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
NCOHLEED_02695	1.09e-13	-	-	-	-	-	-	-	-
NCOHLEED_02696	5.5e-141	-	-	-	-	-	-	-	-
NCOHLEED_02700	9.09e-315	-	-	-	D	-	-	-	Plasmid recombination enzyme
NCOHLEED_02701	4.74e-244	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02702	6.59e-254	-	-	-	T	-	-	-	COG NOG25714 non supervised orthologous group
NCOHLEED_02703	6.58e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF3853)
NCOHLEED_02704	8.93e-35	-	-	-	-	-	-	-	-
NCOHLEED_02705	3.95e-244	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02706	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_02707	7.66e-111	-	-	-	K	-	-	-	Helix-turn-helix domain
NCOHLEED_02708	1.71e-197	-	-	-	H	-	-	-	Methyltransferase domain
NCOHLEED_02709	8.54e-264	-	-	-	K	ko:K03088	-	ko00000,ko03021	Outer membrane protein beta-barrel domain
NCOHLEED_02710	2.89e-100	-	-	-	P	ko:K03711	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02711	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02712	1.61e-130	-	-	-	-	-	-	-	-
NCOHLEED_02713	9.49e-314	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02714	3.39e-183	phnX	3.11.1.1	-	S	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
NCOHLEED_02715	9.34e-253	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
NCOHLEED_02716	1.96e-309	mepA_7	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02717	1.73e-257	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NCOHLEED_02718	1.06e-83	yccF	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02720	4.69e-167	-	-	-	P	-	-	-	TonB-dependent receptor
NCOHLEED_02721	0.0	-	-	-	M	-	-	-	CarboxypepD_reg-like domain
NCOHLEED_02722	4.98e-297	-	-	-	S	-	-	-	Domain of unknown function (DUF4249)
NCOHLEED_02723	9.52e-290	-	-	-	S	-	-	-	Domain of unknown function (DUF4249)
NCOHLEED_02724	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
NCOHLEED_02725	6.01e-24	-	-	-	-	-	-	-	-
NCOHLEED_02726	1.8e-136	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NCOHLEED_02727	4.53e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
NCOHLEED_02728	1.4e-215	-	-	-	KT	-	-	-	COG3279 Response regulator of the LytR AlgR family
NCOHLEED_02729	0.0	-	-	-	H	-	-	-	TonB-dependent receptor plug domain
NCOHLEED_02730	2.95e-92	-	-	-	S	-	-	-	protein conserved in bacteria
NCOHLEED_02731	0.0	-	-	-	E	-	-	-	Transglutaminase-like protein
NCOHLEED_02732	1.97e-187	spoU	-	-	H	ko:K03437	-	ko00000,ko03016	RNA methyltransferase TrmH family
NCOHLEED_02733	1.9e-257	yjmD_2	-	-	E	ko:K18369	ko00640,map00640	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
NCOHLEED_02734	2.86e-139	-	-	-	-	-	-	-	-
NCOHLEED_02735	1.49e-101	-	-	-	S	-	-	-	Lipocalin-like domain
NCOHLEED_02736	1.59e-162	-	-	-	-	-	-	-	-
NCOHLEED_02737	8.15e-94	-	-	-	-	-	-	-	-
NCOHLEED_02738	3.28e-52	-	-	-	-	-	-	-	-
NCOHLEED_02739	6.46e-31	-	-	-	-	-	-	-	-
NCOHLEED_02740	4.22e-136	-	-	-	L	-	-	-	Phage integrase family
NCOHLEED_02741	4.23e-141	-	-	-	L	-	-	-	ScaI restriction endonuclease
NCOHLEED_02742	5.55e-209	-	2.1.1.72	-	L	ko:K00571,ko:K07319	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
NCOHLEED_02743	3.63e-248	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02744	0.0	-	-	-	-	-	-	-	-
NCOHLEED_02745	2.23e-156	-	-	-	-	-	-	-	-
NCOHLEED_02746	7.83e-38	-	-	-	-	-	-	-	-
NCOHLEED_02747	4.93e-69	-	-	-	-	-	-	-	-
NCOHLEED_02748	5.72e-243	-	-	-	-	-	-	-	-
NCOHLEED_02749	4.36e-42	-	-	-	-	-	-	-	-
NCOHLEED_02750	9.09e-201	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02752	2.03e-292	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_02753	4.3e-278	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_02754	8.37e-296	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
NCOHLEED_02755	2.4e-134	-	-	-	S	-	-	-	RloB-like protein
NCOHLEED_02756	2.82e-235	-	-	-	S	-	-	-	COG NOG06093 non supervised orthologous group
NCOHLEED_02757	0.0	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
NCOHLEED_02758	7.41e-59	-	-	-	S	-	-	-	Helix-turn-helix domain
NCOHLEED_02759	2.05e-63	-	-	-	K	-	-	-	COG NOG34759 non supervised orthologous group
NCOHLEED_02760	2.46e-126	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02761	1.2e-91	-	-	-	-	-	-	-	-
NCOHLEED_02762	1.07e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
NCOHLEED_02763	8.71e-84	wcfX	5.1.3.6	-	M	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	NAD dependent epimerase dehydratase family
NCOHLEED_02764	1.04e-215	-	-	-	M	-	-	-	glycosyl transferase family 8
NCOHLEED_02765	3.36e-102	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCOHLEED_02766	6.56e-67	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
NCOHLEED_02768	1.34e-126	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
NCOHLEED_02769	2.55e-218	-	-	GT4	G	ko:K00754	-	ko00000,ko01000	polysaccharide deacetylase
NCOHLEED_02770	2.64e-73	-	-	-	-	-	-	-	-
NCOHLEED_02771	1.15e-117	moaA	4.1.99.22, 4.6.1.17	-	H	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	4Fe-4S single cluster domain
NCOHLEED_02772	1.29e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF512)
NCOHLEED_02774	6.34e-137	-	-	-	C	-	-	-	Iron-sulfur cluster-binding domain
NCOHLEED_02775	1.87e-120	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family
NCOHLEED_02776	4.67e-143	wbpO	1.1.1.136	-	M	ko:K02474,ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NCOHLEED_02777	1.11e-26	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
NCOHLEED_02778	3.26e-251	-	-	-	L	-	-	-	Phage integrase SAM-like domain
NCOHLEED_02780	2.32e-170	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02781	4.89e-111	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02782	7.46e-141	-	-	-	S	-	-	-	COG NOG34011 non supervised orthologous group
NCOHLEED_02783	8.9e-131	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02784	6.45e-100	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NCOHLEED_02785	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_02786	0.0	mltF	-	-	M	ko:K18691	-	ko00000,ko01000,ko01011	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
NCOHLEED_02787	1.85e-143	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
NCOHLEED_02788	6.36e-66	-	-	-	S	-	-	-	Stress responsive A B barrel domain
NCOHLEED_02789	0.0	dsbD	1.8.1.8	-	CO	ko:K04084	-	ko00000,ko01000,ko03110	cytochrome c biogenesis protein transmembrane region
NCOHLEED_02790	7.18e-170	-	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	COG4845 Chloramphenicol O-acetyltransferase
NCOHLEED_02791	6.18e-164	-	-	-	S	-	-	-	Protein of unknown function (DUF2490)
NCOHLEED_02792	7.13e-280	-	-	-	N	-	-	-	Psort location OuterMembrane, score
NCOHLEED_02793	6.75e-120	-	-	-	Q	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02794	1.62e-195	hisG	2.4.2.17	-	F	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
NCOHLEED_02795	1.02e-295	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NCOHLEED_02796	1.09e-252	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NCOHLEED_02797	8.51e-291	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis bifunctional protein HisB
NCOHLEED_02798	0.0	nhaA	-	-	P	ko:K03455	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02799	7.34e-251	-	-	-	S	-	-	-	Oxidoreductase, NAD-binding domain protein
NCOHLEED_02800	5.91e-93	hslR	-	-	J	ko:K04762	-	ko00000,ko03110	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NCOHLEED_02801	2.29e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NCOHLEED_02802	1.71e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NCOHLEED_02803	1.22e-78	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02804	2.62e-06	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02805	1.08e-217	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NCOHLEED_02806	1.88e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	COG1862 Preprotein translocase subunit YajC
NCOHLEED_02807	3.34e-243	-	-	-	S	-	-	-	COG NOG14472 non supervised orthologous group
NCOHLEED_02808	2.31e-132	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NCOHLEED_02809	3.95e-93	-	-	-	S	-	-	-	COG NOG14473 non supervised orthologous group
NCOHLEED_02810	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NCOHLEED_02811	2.86e-140	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02812	7.52e-207	cysL	-	-	K	-	-	-	LysR substrate binding domain protein
NCOHLEED_02813	2.32e-235	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02814	3.64e-70	-	-	-	K	-	-	-	Transcription termination factor nusG
NCOHLEED_02815	5.02e-132	-	-	-	-	-	-	-	-
NCOHLEED_02816	1.41e-70	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NCOHLEED_02817	1.11e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog
NCOHLEED_02818	3.84e-115	-	-	-	-	-	-	-	-
NCOHLEED_02819	2.77e-159	-	-	-	S	-	-	-	Domain of unknown function (DUF4252)
NCOHLEED_02820	5.06e-237	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NCOHLEED_02821	1.47e-104	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	bacterioferritin comigratory protein
NCOHLEED_02822	1.83e-304	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	COG1748 Saccharopine dehydrogenase and related
NCOHLEED_02823	1.62e-185	-	-	-	O	-	-	-	COG COG3187 Heat shock protein
NCOHLEED_02824	8.85e-133	-	-	-	T	-	-	-	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
NCOHLEED_02825	0.0	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
NCOHLEED_02826	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NCOHLEED_02827	6.39e-71	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	domain shared with the mammalian protein Schlafen
NCOHLEED_02828	1.35e-23	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	domain shared with the mammalian protein Schlafen
NCOHLEED_02829	5.86e-294	ydiI	3.1.2.28	-	Q	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02831	0.0	-	-	-	H	-	-	-	COG4206 Outer membrane cobalamin receptor protein
NCOHLEED_02832	1.79e-268	-	-	-	S	-	-	-	amine dehydrogenase activity
NCOHLEED_02833	1.58e-263	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NCOHLEED_02834	1.67e-229	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NCOHLEED_02835	3.81e-08	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02836	5.3e-302	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
NCOHLEED_02837	1.61e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
NCOHLEED_02838	4.19e-204	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
NCOHLEED_02839	0.0	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
NCOHLEED_02840	6.97e-51	-	-	-	S	-	-	-	COG NOG17973 non supervised orthologous group
NCOHLEED_02841	0.0	-	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02842	0.0	trpB	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NCOHLEED_02844	0.0	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02845	1.75e-158	ktrA	-	-	C	ko:K03499	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02846	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3843)
NCOHLEED_02847	4.19e-146	-	-	-	L	-	-	-	COG NOG29822 non supervised orthologous group
NCOHLEED_02849	7.99e-37	-	-	-	-	-	-	-	-
NCOHLEED_02850	8.99e-109	-	-	-	L	-	-	-	DNA-binding protein
NCOHLEED_02851	3.31e-51	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
NCOHLEED_02852	7.48e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF4890)
NCOHLEED_02853	3.67e-126	-	-	-	S	-	-	-	COG NOG28695 non supervised orthologous group
NCOHLEED_02854	7.72e-156	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NCOHLEED_02855	8.22e-306	qseC	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02856	7.93e-99	-	-	-	S	-	-	-	COG NOG31508 non supervised orthologous group
NCOHLEED_02857	3.62e-121	-	-	-	S	-	-	-	COG NOG31242 non supervised orthologous group
NCOHLEED_02858	5.61e-293	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	COG1760 L-serine deaminase
NCOHLEED_02859	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NCOHLEED_02861	3.32e-148	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
NCOHLEED_02862	1.74e-164	-	-	-	S	-	-	-	Glycosyl transferase family 11
NCOHLEED_02863	6.49e-245	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
NCOHLEED_02865	1.17e-210	-	-	-	L	-	-	-	COG COG2801 Transposase and inactivated derivatives
NCOHLEED_02866	1.77e-81	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02867	1.35e-195	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
NCOHLEED_02868	1.19e-128	-	-	-	M	ko:K03286	-	ko00000,ko02000	OmpA family
NCOHLEED_02870	3.4e-184	-	5.1.3.26	-	M	ko:K19997	-	ko00000,ko01000	to Edwardsiella ictaluri UDP-glucose 4-epimerase WbeIT SWALL Q937X6 (EMBL AY057452) (323 aa) fasta scores E()
NCOHLEED_02872	4.27e-293	-	-	-	L	-	-	-	Transposase, Mutator family
NCOHLEED_02873	2.26e-164	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family
NCOHLEED_02874	1.51e-215	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02876	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NCOHLEED_02877	0.0	leuC	4.2.1.33, 4.2.1.35	-	H	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NCOHLEED_02878	8.2e-145	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NCOHLEED_02879	0.0	leuA_1	2.3.1.182	-	E	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the alpha-IPM synthase homocitrate synthase family
NCOHLEED_02880	5.83e-57	-	-	-	-	-	-	-	-
NCOHLEED_02881	2.71e-261	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NCOHLEED_02882	6.83e-236	cysK	2.5.1.47	-	E	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NCOHLEED_02883	2.13e-145	-	-	-	S	-	-	-	COG COG0457 FOG TPR repeat
NCOHLEED_02884	0.0	recQ3	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NCOHLEED_02885	3.54e-105	-	-	-	K	-	-	-	transcriptional regulator (AraC
NCOHLEED_02886	0.0	-	3.4.14.4	-	S	ko:K01277	-	ko00000,ko01000,ko01002	Peptidase family M49
NCOHLEED_02887	5.24e-158	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02888	1.05e-113	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NCOHLEED_02889	1.49e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NCOHLEED_02890	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NCOHLEED_02891	9.96e-152	-	-	-	S	ko:K06973	-	ko00000	neutral zinc metallopeptidase
NCOHLEED_02892	7.64e-286	-	-	-	E	-	-	-	Transglutaminase-like superfamily
NCOHLEED_02893	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
NCOHLEED_02894	4.82e-55	-	-	-	-	-	-	-	-
NCOHLEED_02895	1.12e-176	-	-	-	C	-	-	-	4Fe-4S binding domain protein
NCOHLEED_02896	4.82e-112	-	-	-	T	-	-	-	LytTr DNA-binding domain
NCOHLEED_02897	3.22e-101	-	-	-	T	-	-	-	Histidine kinase
NCOHLEED_02898	7.4e-205	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
NCOHLEED_02899	5.3e-183	-	-	-	S	ko:K03453	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02900	7.64e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NCOHLEED_02901	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NCOHLEED_02902	1.19e-45	-	-	-	S	-	-	-	COG NOG33517 non supervised orthologous group
NCOHLEED_02903	1.66e-252	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_02904	0.0	-	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	polysaccharide deacetylase
NCOHLEED_02905	3.12e-224	dnaJ2	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	Psort location Cytoplasmic, score
NCOHLEED_02906	3.11e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02907	0.0	acd	-	-	C	-	-	-	Acyl-CoA dehydrogenase, C-terminal domain
NCOHLEED_02908	8.84e-163	-	-	-	M	ko:K03832	-	ko00000,ko02000	MORN repeat variant
NCOHLEED_02909	7.59e-245	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Psort location Cytoplasmic, score 8.96
NCOHLEED_02910	1.77e-206	etfB	-	-	C	ko:K03521	-	ko00000	COG2086 Electron transfer flavoprotein beta subunit
NCOHLEED_02911	0.0	dxs2	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NCOHLEED_02912	3.04e-302	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NCOHLEED_02913	5.33e-205	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02914	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02915	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	COG NOG27574 non supervised orthologous group
NCOHLEED_02916	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 32 family
NCOHLEED_02917	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NCOHLEED_02918	0.0	-	-	-	S	-	-	-	COG NOG11699 non supervised orthologous group
NCOHLEED_02919	0.0	-	3.2.1.80	-	M	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
NCOHLEED_02920	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NCOHLEED_02921	3.12e-271	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NCOHLEED_02922	8.89e-215	ydjH_1	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family
NCOHLEED_02923	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_02924	1.48e-37	-	-	-	-	-	-	-	-
NCOHLEED_02925	0.0	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NCOHLEED_02926	2.76e-292	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
NCOHLEED_02927	2.95e-308	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_02928	0.0	yngK	-	-	S	-	-	-	lipoprotein YddW precursor K01189
NCOHLEED_02929	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02930	1.23e-43	-	-	-	S	-	-	-	COG NOG34202 non supervised orthologous group
NCOHLEED_02931	2.28e-117	-	-	-	MU	-	-	-	COG NOG29365 non supervised orthologous group
NCOHLEED_02932	6.92e-64	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein, HigA
NCOHLEED_02933	8.2e-68	-	-	-	S	ko:K07334	-	ko00000,ko02048	Plasmid maintenance system killer protein
NCOHLEED_02934	3.61e-288	-	-	-	M	ko:K03832	-	ko00000,ko02000	Gram-negative bacterial TonB protein C-terminal
NCOHLEED_02935	0.0	uvrA1	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NCOHLEED_02936	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_02937	0.0	yngK	-	-	S	-	-	-	lipoprotein YddW precursor
NCOHLEED_02938	2.76e-129	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02939	8.3e-123	chrA	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
NCOHLEED_02940	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02941	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
NCOHLEED_02942	0.0	nagZ3	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
NCOHLEED_02943	1.24e-148	-	-	-	E	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02944	4.83e-126	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_02945	4.37e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NCOHLEED_02946	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NCOHLEED_02947	8.28e-176	-	-	-	S	-	-	-	Tetratricopeptide repeat
NCOHLEED_02948	8.01e-64	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
NCOHLEED_02949	1.14e-24	-	-	-	L	-	-	-	domain protein
NCOHLEED_02950	1.41e-281	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	COG2189 Adenine specific DNA methylase Mod
NCOHLEED_02951	9.67e-74	-	-	-	S	-	-	-	COG3943 Virulence protein
NCOHLEED_02952	0.0	-	3.1.21.5	-	V	ko:K01156	-	ko00000,ko01000,ko02048	to Salmonella typhimurium type III restriction-modification system Stylti enzyme Res or STM0358 SWALL T3RE_SALTY (SWALL P40815) (990 aa) fasta scores E()
NCOHLEED_02953	6.35e-92	-	-	-	L	-	-	-	DNA-binding protein
NCOHLEED_02954	7.95e-41	-	4.1.1.3	-	C	ko:K01573	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Sodium pump decarboxylase gamma subunit
NCOHLEED_02955	0.0	cfiA	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG5016 Pyruvate oxaloacetate carboxyltransferase
NCOHLEED_02956	8.84e-285	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	sodium ion-translocating decarboxylase, beta subunit
NCOHLEED_02957	8.1e-299	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
NCOHLEED_02958	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_02959	7.21e-241	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_02960	0.0	-	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
NCOHLEED_02961	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02962	1.84e-238	cytR	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.97
NCOHLEED_02963	5.92e-303	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan endo-1,4-beta-galactosidase
NCOHLEED_02964	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NCOHLEED_02965	0.0	-	-	-	P	ko:K21573	-	ko00000,ko02000	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02966	0.0	susD	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_02967	0.0	-	-	-	S	ko:K21571	-	ko00000	SusE outer membrane protein
NCOHLEED_02968	0.0	-	-	-	G	-	-	-	Maltogenic Amylase, C-terminal domain
NCOHLEED_02969	0.0	treZ_2	-	-	M	-	-	-	branching enzyme
NCOHLEED_02970	5.82e-250	-	-	-	V	-	-	-	COG NOG22551 non supervised orthologous group
NCOHLEED_02971	3.38e-313	-	-	-	S	-	-	-	Protein of unknown function (DUF4026)
NCOHLEED_02972	3.4e-120	-	-	-	C	-	-	-	Nitroreductase family
NCOHLEED_02973	9.32e-70	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02974	5.74e-178	-	-	-	S	-	-	-	NADP oxidoreductase coenzyme F420-dependent
NCOHLEED_02975	2.82e-127	kdsC	3.1.3.45	-	S	ko:K03270	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family
NCOHLEED_02976	6.76e-139	maf	-	-	D	ko:K06287	-	ko00000	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
NCOHLEED_02977	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_02978	7.08e-251	-	-	-	P	-	-	-	phosphate-selective porin O and P
NCOHLEED_02979	2.93e-298	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score
NCOHLEED_02980	6.92e-163	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NCOHLEED_02981	2.94e-281	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02982	6.04e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NCOHLEED_02983	0.0	-	-	-	O	-	-	-	non supervised orthologous group
NCOHLEED_02984	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_02985	1.87e-310	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_02986	5.95e-265	fsr	-	-	G	ko:K08223	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02987	2.33e-87	-	-	-	E	ko:K08717	-	ko00000,ko02000	urea transporter
NCOHLEED_02988	1.16e-110	-	-	-	E	ko:K08717	-	ko00000,ko02000	urea transporter
NCOHLEED_02990	2.13e-68	-	-	-	S	-	-	-	COG NOG30624 non supervised orthologous group
NCOHLEED_02991	4.43e-135	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NCOHLEED_02992	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NCOHLEED_02993	0.0	modF	-	-	P	ko:K05776	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC molybdenum transporter, ATP-binding subunit modF
NCOHLEED_02994	1.84e-155	tal	2.2.1.2	-	F	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NCOHLEED_02995	0.0	ltaS2	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_02996	2.21e-163	ybjG	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_02997	0.0	-	-	-	P	-	-	-	CarboxypepD_reg-like domain
NCOHLEED_02998	1.66e-211	-	-	-	S	-	-	-	Protein of unknown function (Porph_ging)
NCOHLEED_02999	0.0	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	histidine kinase DNA gyrase B
NCOHLEED_03000	5.66e-159	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NCOHLEED_03001	2.54e-281	ybdG_1	-	-	M	ko:K16053	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03002	3.72e-263	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
NCOHLEED_03003	0.0	pepD_1	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
NCOHLEED_03004	2.46e-43	-	-	-	S	-	-	-	COG NOG35566 non supervised orthologous group
NCOHLEED_03005	9.45e-131	-	-	-	M	ko:K06142	-	ko00000	membrane
NCOHLEED_03006	6.12e-182	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NCOHLEED_03007	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NCOHLEED_03008	2.57e-60	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NCOHLEED_03009	4.97e-64	-	-	-	S	-	-	-	COG NOG23407 non supervised orthologous group
NCOHLEED_03011	3.95e-116	-	-	-	-	-	-	-	-
NCOHLEED_03012	3.89e-136	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03013	3.7e-139	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03014	4.43e-61	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NCOHLEED_03015	3.12e-172	-	-	-	NU	-	-	-	Type IV pilus biogenesis stability protein PilW
NCOHLEED_03016	2.46e-138	mtnN	3.2.2.9	-	F	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NCOHLEED_03017	3.97e-77	-	-	-	S	ko:K09790	-	ko00000	Psort location CytoplasmicMembrane, score
NCOHLEED_03018	4.95e-214	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Pyridoxal kinase
NCOHLEED_03019	2.06e-195	-	-	-	G	-	-	-	COG COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NCOHLEED_03020	1.18e-76	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	Psort location Cytoplasmic, score
NCOHLEED_03021	5.04e-137	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NCOHLEED_03023	1.92e-138	mug	-	-	L	-	-	-	COG3663 G T U mismatch-specific DNA glycosylase
NCOHLEED_03024	0.0	eam	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	KamA family
NCOHLEED_03025	8.45e-147	-	-	-	S	-	-	-	COG NOG25304 non supervised orthologous group
NCOHLEED_03026	0.0	agcS	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
NCOHLEED_03027	3.83e-149	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03028	1.14e-28	-	-	-	S	-	-	-	COG NOG16623 non supervised orthologous group
NCOHLEED_03029	2.77e-309	-	-	-	S	-	-	-	DNA-binding protein with the Helix-hairpin-helix motif
NCOHLEED_03030	1.11e-189	-	-	-	L	-	-	-	DNA metabolism protein
NCOHLEED_03031	6.27e-145	-	-	-	S	ko:K07507	-	ko00000,ko02000	Mg2 transporter-C family protein
NCOHLEED_03032	4.38e-242	mltD_2	-	-	M	-	-	-	Transglycosylase SLT domain protein
NCOHLEED_03033	1.5e-170	-	-	-	S	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
NCOHLEED_03034	1.78e-97	yjbQ	-	-	S	-	-	-	Secondary thiamine-phosphate synthase enzyme
NCOHLEED_03035	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
NCOHLEED_03036	1.58e-189	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NCOHLEED_03037	1.4e-105	nodN	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03038	3.8e-47	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03039	8.03e-81	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03040	1.46e-64	-	-	-	S	-	-	-	COG NOG23408 non supervised orthologous group
NCOHLEED_03041	7.82e-111	yvbK	2.3.1.82	-	K	ko:K18815	-	br01600,ko00000,ko01000,ko01504	Psort location Cytoplasmic, score 8.96
NCOHLEED_03042	6.3e-105	-	-	-	S	-	-	-	COG NOG29454 non supervised orthologous group
NCOHLEED_03043	4.72e-76	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
NCOHLEED_03044	1.93e-206	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NCOHLEED_03045	3.27e-92	gloA	4.4.1.5	-	E	ko:K01759,ko:K03827	ko00620,map00620	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
NCOHLEED_03046	4.84e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase, gnat family
NCOHLEED_03047	0.0	rluA	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	Pseudouridine synthase, RluA family
NCOHLEED_03048	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_03049	2.54e-209	-	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
NCOHLEED_03050	3.88e-165	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NCOHLEED_03051	0.0	clpA	-	-	O	ko:K03694	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NCOHLEED_03052	1.32e-63	clpS	-	-	S	ko:K06891	-	ko00000	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NCOHLEED_03053	5.45e-126	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_03054	1.21e-207	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
NCOHLEED_03055	8.74e-260	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03056	2.78e-107	-	-	-	S	-	-	-	COG NOG19145 non supervised orthologous group
NCOHLEED_03057	7.34e-99	-	-	-	MP	ko:K06079	ko01503,map01503	ko00000,ko00001	COG NOG29769 non supervised orthologous group
NCOHLEED_03058	5.63e-293	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
NCOHLEED_03059	1.65e-202	-	3.1.2.12	CE1	S	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	ko00000,ko00001,ko01000	esterase
NCOHLEED_03060	6.02e-216	-	-	-	S	-	-	-	COG NOG30864 non supervised orthologous group
NCOHLEED_03061	0.0	-	-	-	M	-	-	-	peptidase S41
NCOHLEED_03062	9.66e-309	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
NCOHLEED_03063	6.71e-267	trmU	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NCOHLEED_03064	9.77e-152	narL	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NCOHLEED_03065	6.18e-109	-	-	-	S	-	-	-	COG NOG27363 non supervised orthologous group
NCOHLEED_03066	1.17e-305	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03067	4.67e-279	ynfM	-	-	EGP	ko:K08224	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03068	0.0	-	-	-	T	-	-	-	helix_turn_helix, arabinose operon control protein
NCOHLEED_03069	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NCOHLEED_03070	6.03e-216	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
NCOHLEED_03071	9.32e-211	-	-	-	S	-	-	-	UPF0365 protein
NCOHLEED_03072	5.63e-97	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03073	0.0	-	-	-	S	-	-	-	COG NOG11656 non supervised orthologous group
NCOHLEED_03074	3.83e-177	ttcA	-	-	H	ko:K14058	-	ko00000,ko03016	Belongs to the TtcA family
NCOHLEED_03075	5.57e-83	-	-	-	S	ko:K09922	-	ko00000	Psort location CytoplasmicMembrane, score
NCOHLEED_03076	1.48e-246	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NCOHLEED_03077	1.11e-125	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NCOHLEED_03078	5.13e-193	-	-	-	S	-	-	-	COG NOG28307 non supervised orthologous group
NCOHLEED_03079	1.55e-110	-	-	-	S	-	-	-	COG NOG30522 non supervised orthologous group
NCOHLEED_03080	2.5e-232	arnC	-	-	M	-	-	-	involved in cell wall biogenesis
NCOHLEED_03081	4.13e-127	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03084	1.4e-239	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NCOHLEED_03085	1.99e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_03086	6.31e-222	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03087	4.62e-311	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_03088	7.81e-239	-	-	-	S	-	-	-	Glycosyl transferase family 2
NCOHLEED_03089	6.58e-285	-	-	-	S	-	-	-	Glycosyltransferase WbsX
NCOHLEED_03090	1.32e-248	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCOHLEED_03091	3.19e-225	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NCOHLEED_03092	0.0	-	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score
NCOHLEED_03093	1.76e-182	-	-	-	T	-	-	-	Lipopolysaccharide kinase (Kdo/WaaP) family
NCOHLEED_03094	4.95e-134	gmhA	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
NCOHLEED_03095	1.88e-116	gmhB	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
NCOHLEED_03096	0.0	rfaE	2.7.1.167, 2.7.7.70	-	H	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NCOHLEED_03097	9.25e-247	-	-	GT9	M	ko:K02843	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyltransferase family 9
NCOHLEED_03098	1.56e-229	-	-	-	S	-	-	-	Glycosyl transferase family 2
NCOHLEED_03099	4.75e-209	-	-	-	M	ko:K07271	-	ko00000,ko01000	COG COG3475 LPS biosynthesis protein
NCOHLEED_03100	5.01e-170	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03101	8.29e-252	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	COG COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase
NCOHLEED_03102	4.31e-279	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
NCOHLEED_03104	2.1e-34	-	-	-	-	-	-	-	-
NCOHLEED_03105	1.61e-250	pdxB	1.1.1.290	-	H	ko:K03473	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
NCOHLEED_03106	0.0	-	-	-	S	ko:K07014	-	ko00000	Domain of unknown function (DUF3413)
NCOHLEED_03107	3.57e-141	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NCOHLEED_03108	7.43e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NCOHLEED_03109	2.96e-304	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NCOHLEED_03110	8.81e-201	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NCOHLEED_03111	5.76e-243	pfkA	2.7.1.11, 2.7.1.90	-	F	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NCOHLEED_03112	0.0	-	-	-	H	-	-	-	GH3 auxin-responsive promoter
NCOHLEED_03113	1.32e-215	-	-	-	M	-	-	-	COG NOG19097 non supervised orthologous group
NCOHLEED_03114	4.95e-259	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NCOHLEED_03115	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NCOHLEED_03116	0.0	-	-	-	M	ko:K07001	-	ko00000	Phospholipase, patatin family
NCOHLEED_03117	0.0	aslA	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
NCOHLEED_03118	1.05e-295	-	-	-	O	-	-	-	Glycosyl Hydrolase Family 88
NCOHLEED_03119	1.17e-96	paaI	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	phenylacetic acid degradation protein
NCOHLEED_03120	1.6e-206	-	-	-	S	-	-	-	Protein of unknown function (DUF3108)
NCOHLEED_03121	0.0	-	-	-	S	-	-	-	COG NOG07965 non supervised orthologous group
NCOHLEED_03122	1.99e-248	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCOHLEED_03123	0.0	mexF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NCOHLEED_03124	0.0	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
NCOHLEED_03125	1.29e-187	lpxA2	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NCOHLEED_03126	1.06e-176	-	-	-	T	-	-	-	Carbohydrate-binding family 9
NCOHLEED_03127	4.19e-264	mdsC	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03128	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_03129	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
NCOHLEED_03130	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03131	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_03132	0.0	-	4.2.2.5	PL8	N	ko:K19049	-	ko00000,ko01000	Polysaccharide lyase family 8, super-sandwich domain protein
NCOHLEED_03133	2.85e-291	-	-	-	G	-	-	-	beta-fructofuranosidase activity
NCOHLEED_03134	7.54e-241	dus	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NCOHLEED_03135	0.0	-	4.2.2.20, 4.2.2.21	-	H	ko:K08961	-	ko00000,ko01000	Chondroitin sulfate ABC lyase
NCOHLEED_03136	2.07e-171	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03137	1.93e-122	-	-	-	S	-	-	-	COG NOG28211 non supervised orthologous group
NCOHLEED_03138	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03139	2.22e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapB family
NCOHLEED_03140	0.0	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	signal peptidase i
NCOHLEED_03141	5.81e-221	lepB_1	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NCOHLEED_03142	5.3e-157	-	-	-	C	-	-	-	WbqC-like protein
NCOHLEED_03143	1.59e-307	-	-	-	S	-	-	-	Glycosyl Hydrolase Family 88
NCOHLEED_03144	1.18e-186	uxuB	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
NCOHLEED_03145	1.94e-291	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
NCOHLEED_03146	7.65e-142	aqpZ	-	-	G	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NCOHLEED_03147	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
NCOHLEED_03148	0.0	-	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NCOHLEED_03149	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03150	6e-288	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03151	4.58e-140	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NCOHLEED_03152	2.69e-228	-	-	-	S	-	-	-	Metalloenzyme superfamily
NCOHLEED_03153	2.63e-304	-	-	-	S	-	-	-	Belongs to the peptidase M16 family
NCOHLEED_03154	1.2e-138	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	sugar phosphate isomerase involved in capsule formation
NCOHLEED_03155	3.39e-226	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG COG0524 Sugar kinases, ribokinase family
NCOHLEED_03156	0.0	-	-	-	-	-	-	-	-
NCOHLEED_03157	3.74e-148	-	-	-	S	-	-	-	Domain of unknown function (DUF5043)
NCOHLEED_03158	1.11e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF5043)
NCOHLEED_03159	6.09e-254	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_03160	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
NCOHLEED_03161	1.05e-113	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NCOHLEED_03162	6.25e-217	oxyR	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	Psort location Cytoplasmic, score 9.97
NCOHLEED_03163	2.47e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
NCOHLEED_03164	0.0	ahpF	-	-	C	ko:K03387	-	ko00000,ko01000	alkyl hydroperoxide reductase subunit F
NCOHLEED_03165	0.0	-	-	-	E	-	-	-	COG NOG04781 non supervised orthologous group
NCOHLEED_03166	1.22e-307	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03167	3.83e-155	dinD	-	-	S	ko:K14623	-	ko00000,ko03400	DNA-damage-inducible protein D
NCOHLEED_03168	0.0	cap	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NCOHLEED_03169	1.51e-280	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NCOHLEED_03170	0.0	-	-	-	O	-	-	-	COG NOG08360 non supervised orthologous group
NCOHLEED_03171	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_03172	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03173	1.07e-237	-	-	-	G	ko:K05340	-	ko00000,ko02000	COG NOG04879 non supervised orthologous group
NCOHLEED_03174	9.21e-216	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCOHLEED_03175	1.92e-211	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCOHLEED_03176	0.0	-	-	-	-	-	-	-	-
NCOHLEED_03177	5.9e-184	-	-	-	L	-	-	-	DNA alkylation repair enzyme
NCOHLEED_03178	7.38e-254	-	-	-	S	-	-	-	Psort location Extracellular, score
NCOHLEED_03179	2.15e-280	spmA	-	-	S	ko:K06373	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03180	3.19e-96	ybeY	-	-	S	-	-	-	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NCOHLEED_03181	1.76e-131	-	-	-	-	-	-	-	-
NCOHLEED_03182	4.81e-278	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
NCOHLEED_03183	0.0	-	-	-	O	-	-	-	COG NOG25094 non supervised orthologous group
NCOHLEED_03184	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
NCOHLEED_03185	1.1e-260	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	hydrolase, family 43
NCOHLEED_03186	1.59e-242	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
NCOHLEED_03187	6e-247	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
NCOHLEED_03188	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
NCOHLEED_03189	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_03190	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03191	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_03192	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
NCOHLEED_03193	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_03194	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03195	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NCOHLEED_03196	8.76e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NCOHLEED_03197	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NCOHLEED_03198	1.21e-104	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NCOHLEED_03199	1.6e-75	ypjD	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
NCOHLEED_03200	8.14e-209	deoC	4.1.2.4	-	H	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NCOHLEED_03201	1.27e-224	ispB	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NCOHLEED_03202	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NCOHLEED_03203	1.68e-90	-	-	-	S	-	-	-	COG NOG29882 non supervised orthologous group
NCOHLEED_03204	6.7e-148	-	-	-	S	ko:K06950	-	ko00000	Psort location Cytoplasmic, score 8.96
NCOHLEED_03206	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 43
NCOHLEED_03207	6.95e-262	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NCOHLEED_03208	1.2e-52	-	-	-	S	-	-	-	Virulence protein RhuM family
NCOHLEED_03209	1.46e-198	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NCOHLEED_03210	4.21e-60	-	-	-	S	-	-	-	ORF6N domain
NCOHLEED_03211	1.33e-228	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NCOHLEED_03212	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
NCOHLEED_03213	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
NCOHLEED_03214	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	COG NOG04002 non supervised orthologous group
NCOHLEED_03215	0.0	-	-	-	G	-	-	-	cog cog3537
NCOHLEED_03216	1.58e-288	-	-	-	G	-	-	-	Glycosyl hydrolase
NCOHLEED_03217	5.68e-280	-	-	-	S	ko:K21571	-	ko00000	SusE outer membrane protein
NCOHLEED_03218	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_03219	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03220	0.0	-	-	-	S	ko:K09704	-	ko00000	Conserved protein
NCOHLEED_03221	1.86e-310	-	-	-	G	-	-	-	Glycosyl hydrolase
NCOHLEED_03222	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
NCOHLEED_03223	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
NCOHLEED_03224	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
NCOHLEED_03225	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
NCOHLEED_03226	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
NCOHLEED_03227	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NCOHLEED_03228	5.42e-44	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
NCOHLEED_03229	3.1e-119	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
NCOHLEED_03231	1.67e-113	-	-	-	S	-	-	-	Family of unknown function (DUF3836)
NCOHLEED_03232	3.49e-27	fic	-	-	D	ko:K04095	-	ko00000,ko03036	FIC family
NCOHLEED_03233	3.68e-77	-	-	-	S	-	-	-	Cupin domain
NCOHLEED_03234	3.23e-308	-	-	-	M	-	-	-	tail specific protease
NCOHLEED_03235	1.19e-93	-	-	-	S	-	-	-	COG NOG29882 non supervised orthologous group
NCOHLEED_03236	3.44e-204	-	-	-	S	-	-	-	COG NOG34575 non supervised orthologous group
NCOHLEED_03237	4.47e-163	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NCOHLEED_03238	5.47e-120	-	-	-	S	-	-	-	Putative zincin peptidase
NCOHLEED_03239	0.0	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_03240	0.0	-	-	-	S	-	-	-	COG NOG11699 non supervised orthologous group
NCOHLEED_03241	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolase family 38 C-terminal domain protein
NCOHLEED_03242	9.73e-38	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolase family 38 C-terminal domain protein
NCOHLEED_03243	3.6e-278	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
NCOHLEED_03244	1.04e-296	-	-	-	G	-	-	-	Domain of unknown function (DUF4185)
NCOHLEED_03245	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
NCOHLEED_03246	3.76e-302	-	-	-	S	-	-	-	COG NOG11699 non supervised orthologous group
NCOHLEED_03247	0.0	-	-	-	S	ko:K09704	-	ko00000	Pfam:DUF1237
NCOHLEED_03248	2.03e-67	yitW	-	-	S	-	-	-	FeS assembly SUF system protein
NCOHLEED_03249	1.3e-191	lpxH	3.6.1.54	-	S	ko:K03269	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Psort location Cytoplasmic, score
NCOHLEED_03250	0.0	-	-	-	G	-	-	-	YdjC-like protein
NCOHLEED_03251	1.37e-41	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03252	0.0	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
NCOHLEED_03253	6.74e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NCOHLEED_03254	3.55e-234	pta	2.3.1.8	-	C	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_03256	2.1e-71	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
NCOHLEED_03257	3.09e-149	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03258	7.15e-230	-	-	-	S	ko:K01163	-	ko00000	Conserved protein
NCOHLEED_03259	5.37e-249	-	-	-	S	-	-	-	acetyltransferase involved in intracellular survival and related
NCOHLEED_03260	0.0	tldD3	-	-	S	ko:K03592	-	ko00000,ko01002	Psort location Cytoplasmic, score 9.26
NCOHLEED_03261	0.0	tldD1	-	-	S	ko:K03568	-	ko00000,ko01002	and their inactivated homologs
NCOHLEED_03262	4.96e-171	dacA	-	-	S	-	-	-	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NCOHLEED_03263	1.19e-197	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_03264	7.41e-315	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NCOHLEED_03265	1.18e-90	fjo27	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
NCOHLEED_03266	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NCOHLEED_03267	3.15e-230	comEA	-	-	L	-	-	-	COG COG1555 DNA uptake protein and related DNA-binding proteins
NCOHLEED_03268	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
NCOHLEED_03269	5.45e-153	lolD	-	-	V	ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner
NCOHLEED_03270	8.04e-168	hypB	-	-	H	ko:K22132	-	ko00000,ko03016	involved in molybdopterin and thiamine biosynthesis family 1
NCOHLEED_03271	0.0	ybaL_1	-	-	PT	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03272	1.99e-238	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NCOHLEED_03273	0.0	-	-	-	S	-	-	-	pyrogenic exotoxin B
NCOHLEED_03274	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG25802 non supervised orthologous group
NCOHLEED_03275	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03276	9.18e-31	-	-	-	-	-	-	-	-
NCOHLEED_03277	2.42e-201	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03278	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03279	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_03280	0.0	-	-	-	-	-	-	-	-
NCOHLEED_03281	1.94e-59	-	-	-	H	-	-	-	Nucleotidyltransferase substrate-binding family protein
NCOHLEED_03282	2.79e-69	-	-	-	S	-	-	-	Nucleotidyltransferase domain
NCOHLEED_03283	2.62e-145	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03284	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
NCOHLEED_03285	8.92e-310	-	-	-	S	-	-	-	protein conserved in bacteria
NCOHLEED_03286	0.0	-	-	-	E	-	-	-	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NCOHLEED_03287	0.0	-	-	-	M	-	-	-	fibronectin type III domain protein
NCOHLEED_03288	0.0	-	-	-	M	-	-	-	PQQ enzyme repeat
NCOHLEED_03289	0.0	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NCOHLEED_03290	3.28e-229	-	-	-	F	-	-	-	Domain of unknown function (DUF4922)
NCOHLEED_03291	0.0	lytB	-	-	D	ko:K06381	-	ko00000	SpoIID LytB domain protein
NCOHLEED_03292	0.0	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03293	2.1e-309	-	-	-	S	-	-	-	Protein of unknown function (DUF1343)
NCOHLEED_03294	0.0	-	-	-	C	ko:K18930	-	ko00000	FAD binding domain
NCOHLEED_03295	1.32e-291	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03296	6.69e-202	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03297	3.27e-188	murQ	4.2.1.126	-	H	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NCOHLEED_03298	0.0	estA	-	-	EV	-	-	-	beta-lactamase
NCOHLEED_03299	6.68e-156	-	5.2.1.8	-	M	ko:K01802,ko:K03773	-	ko00000,ko01000,ko03110	FkbP-type peptidyl-prolyl cis-trans
NCOHLEED_03300	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
NCOHLEED_03301	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
NCOHLEED_03302	1.06e-299	-	-	-	P	ko:K07214	-	ko00000	Putative esterase
NCOHLEED_03303	0.0	-	-	-	E	-	-	-	Protein of unknown function (DUF1593)
NCOHLEED_03304	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_03305	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03306	5.32e-201	-	-	-	G	ko:K05340	-	ko00000,ko02000	COG NOG04879 non supervised orthologous group
NCOHLEED_03307	0.0	-	-	-	G	-	-	-	L-fucose isomerase, C-terminal domain
NCOHLEED_03308	0.0	-	-	-	G	-	-	-	FGGY family of carbohydrate kinases, N-terminal domain
NCOHLEED_03309	8.94e-221	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
NCOHLEED_03310	2.72e-200	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	XFP N-terminal domain
NCOHLEED_03311	1.41e-143	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NCOHLEED_03312	5.36e-170	-	-	-	K	ko:K02081	-	ko00000,ko03000	DeoR C terminal sensor domain
NCOHLEED_03313	0.0	-	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	DNA mismatch repair protein
NCOHLEED_03314	4.45e-278	-	-	-	M	-	-	-	Glycosyl hydrolases family 43
NCOHLEED_03315	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NCOHLEED_03316	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_03317	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03318	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_03319	0.0	-	-	-	-	-	-	-	-
NCOHLEED_03320	0.0	-	-	-	G	-	-	-	Cellulase (glycosyl hydrolase family 5)
NCOHLEED_03321	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
NCOHLEED_03322	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
NCOHLEED_03323	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
NCOHLEED_03324	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG COG3250 Beta-galactosidase beta-glucuronidase
NCOHLEED_03325	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NCOHLEED_03326	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
NCOHLEED_03327	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
NCOHLEED_03329	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit
NCOHLEED_03330	7.14e-195	-	-	-	S	-	-	-	COG NOG19130 non supervised orthologous group
NCOHLEED_03331	2.28e-256	-	-	-	M	-	-	-	peptidase S41
NCOHLEED_03333	0.0	-	-	-	KT	-	-	-	COG NOG11230 non supervised orthologous group
NCOHLEED_03334	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03335	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
NCOHLEED_03336	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
NCOHLEED_03337	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
NCOHLEED_03338	0.0	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
NCOHLEED_03339	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03340	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG26302 non supervised orthologous group
NCOHLEED_03341	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
NCOHLEED_03342	4.94e-191	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
NCOHLEED_03343	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
NCOHLEED_03344	0.0	-	-	-	M	-	-	-	TonB-dependent receptor
NCOHLEED_03345	1.63e-297	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03346	2.71e-108	cyaA	4.6.1.1	-	S	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_03347	1.14e-09	-	-	-	-	-	-	-	-
NCOHLEED_03348	5.73e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NCOHLEED_03349	1.15e-183	-	-	-	T	-	-	-	COG NOG17272 non supervised orthologous group
NCOHLEED_03350	0.0	-	-	-	Q	-	-	-	depolymerase
NCOHLEED_03351	1.63e-309	-	-	-	S	-	-	-	Domain of unknown function (DUF5009)
NCOHLEED_03352	0.0	-	-	-	M	-	-	-	Cellulase N-terminal ig-like domain
NCOHLEED_03353	2.86e-254	-	-	-	O	-	-	-	Dual-action HEIGH metallo-peptidase
NCOHLEED_03354	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
NCOHLEED_03355	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03356	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
NCOHLEED_03357	1.58e-146	-	-	-	M	-	-	-	COG NOG19089 non supervised orthologous group
NCOHLEED_03358	1.56e-257	argE	3.5.1.16	-	E	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related
NCOHLEED_03359	2.9e-239	envC	-	-	D	-	-	-	Peptidase, M23
NCOHLEED_03360	2.82e-125	-	-	-	S	-	-	-	COG NOG29315 non supervised orthologous group
NCOHLEED_03361	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
NCOHLEED_03362	1.04e-98	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NCOHLEED_03363	0.0	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
NCOHLEED_03364	3.06e-237	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03365	4.6e-201	-	-	-	I	-	-	-	Acyl-transferase
NCOHLEED_03366	1.22e-116	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NCOHLEED_03367	4.75e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NCOHLEED_03368	0.0	-	-	-	S	ko:K09704	-	ko00000	Conserved protein
NCOHLEED_03369	2.13e-111	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NCOHLEED_03370	1.17e-216	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NCOHLEED_03371	3.3e-70	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03372	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Cell division protein FtsI penicillin-binding protein
NCOHLEED_03373	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NCOHLEED_03374	5.94e-300	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NCOHLEED_03375	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NCOHLEED_03376	6.77e-305	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NCOHLEED_03377	2.42e-291	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NCOHLEED_03378	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NCOHLEED_03379	1.44e-170	ftsQ	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Psort location Cytoplasmic, score 8.96
NCOHLEED_03380	2.96e-305	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NCOHLEED_03381	4.71e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NCOHLEED_03382	4.18e-91	-	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NCOHLEED_03383	8.71e-175	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NCOHLEED_03385	8.63e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NCOHLEED_03386	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCOHLEED_03387	3.36e-141	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03388	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NCOHLEED_03389	5.68e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.96
NCOHLEED_03390	7.27e-145	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NCOHLEED_03391	0.0	-	-	-	KT	-	-	-	tetratricopeptide repeat
NCOHLEED_03392	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03393	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
NCOHLEED_03394	2.85e-53	-	-	-	S	-	-	-	COG NOG18433 non supervised orthologous group
NCOHLEED_03395	2.52e-135	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03396	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
NCOHLEED_03397	0.0	ygjK	-	GH63	G	ko:K03931	-	ko00000	Glycoside hydrolase
NCOHLEED_03398	9.87e-263	buk	2.7.2.7	-	H	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
NCOHLEED_03399	7.09e-222	-	2.3.1.19, 2.3.1.8	-	C	ko:K00625,ko:K00634	ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
NCOHLEED_03400	4.16e-233	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
NCOHLEED_03401	7.27e-242	ywaD	-	-	S	-	-	-	glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683
NCOHLEED_03402	4.14e-94	sufE	-	-	S	ko:K02426	-	ko00000	COG2166 SufE protein probably involved in Fe-S center assembly
NCOHLEED_03403	1.76e-69	-	-	-	-	-	-	-	-
NCOHLEED_03404	1.07e-179	-	-	-	-	-	-	-	-
NCOHLEED_03405	1.58e-126	-	-	-	-	-	-	-	-
NCOHLEED_03406	1.15e-70	-	-	-	S	-	-	-	Helix-turn-helix domain
NCOHLEED_03407	5.24e-58	-	-	-	S	-	-	-	RteC protein
NCOHLEED_03408	2.39e-37	-	-	-	-	-	-	-	-
NCOHLEED_03409	2.59e-187	-	2.1.1.266	-	S	ko:K07115	-	ko00000,ko01000,ko03009	COG COG2961 Protein involved in catabolism of external DNA
NCOHLEED_03410	7.26e-120	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NCOHLEED_03411	0.000285	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
NCOHLEED_03412	3.78e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
NCOHLEED_03413	2.4e-65	-	-	-	K	-	-	-	Helix-turn-helix domain
NCOHLEED_03414	3.31e-58	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3876)
NCOHLEED_03415	2.88e-53	-	-	-	S	-	-	-	MerR HTH family regulatory protein
NCOHLEED_03417	6e-24	-	-	-	-	-	-	-	-
NCOHLEED_03418	6.88e-297	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_03419	6.27e-290	-	-	-	L	-	-	-	Arm DNA-binding domain
NCOHLEED_03420	2.1e-64	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03421	6.79e-20	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03422	0.0	-	-	-	LV	-	-	-	COG COG1002 Type II restriction enzyme, methylase subunits
NCOHLEED_03423	1.37e-285	-	-	-	LV	-	-	-	COG COG1002 Type II restriction enzyme, methylase subunits
NCOHLEED_03424	5.41e-146	-	-	-	LV	-	-	-	COG COG1002 Type II restriction enzyme, methylase subunits
NCOHLEED_03425	2.32e-169	-	-	-	L	-	-	-	Transposase domain (DUF772)
NCOHLEED_03426	5.58e-59	-	-	-	L	-	-	-	Transposase, Mutator family
NCOHLEED_03427	0.0	-	-	-	C	-	-	-	lyase activity
NCOHLEED_03428	0.0	-	-	-	C	-	-	-	HEAT repeats
NCOHLEED_03429	0.0	-	-	-	C	-	-	-	lyase activity
NCOHLEED_03430	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score
NCOHLEED_03431	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4876)
NCOHLEED_03432	0.0	-	-	-	P	-	-	-	COG NOG11715 non supervised orthologous group
NCOHLEED_03435	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03436	1.56e-198	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03439	2.18e-88	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03440	2.22e-186	-	-	-	D	-	-	-	ATPase involved in chromosome partitioning K01529
NCOHLEED_03441	5.66e-88	-	-	-	S	-	-	-	COG NOG29850 non supervised orthologous group
NCOHLEED_03442	4.88e-96	-	-	-	S	-	-	-	COG NOG28168 non supervised orthologous group
NCOHLEED_03443	1.39e-128	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
NCOHLEED_03444	1.7e-200	-	-	-	E	-	-	-	Belongs to the arginase family
NCOHLEED_03445	0.0	glgP	2.4.1.1, 2.4.1.11, 2.4.1.8	GH65,GT3,GT35	G	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	Protein of unknown function (DUF3417)
NCOHLEED_03446	0.0	-	-	-	P	ko:K03455	-	ko00000	PTS system, fructose-specific IIABC component K02768 K02769
NCOHLEED_03447	4.15e-232	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NCOHLEED_03448	7.6e-113	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-directed RNA polymerase sigma subunit PrtI (ECF sigma factor) K00960
NCOHLEED_03449	2.78e-88	hsp20	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NCOHLEED_03450	5.48e-186	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NCOHLEED_03451	3.84e-259	fbaB	4.1.2.13	-	G	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
NCOHLEED_03452	9.33e-109	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
NCOHLEED_03453	6.2e-146	-	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
NCOHLEED_03454	2.28e-101	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
NCOHLEED_03455	1.37e-49	-	-	-	-	-	-	-	-
NCOHLEED_03456	1.93e-34	-	-	-	-	-	-	-	-
NCOHLEED_03457	3.68e-73	-	-	-	-	-	-	-	-
NCOHLEED_03458	1.12e-107	-	-	-	L	-	-	-	COG COG3666 Transposase and inactivated derivatives
NCOHLEED_03459	2.35e-44	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03460	1.41e-59	-	-	-	S	-	-	-	COG NOG30576 non supervised orthologous group
NCOHLEED_03461	5.98e-91	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03462	1.03e-150	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NCOHLEED_03463	3.08e-08	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_03464	2.84e-32	-	-	-	-	-	-	-	-
NCOHLEED_03466	1.94e-249	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_03468	2.85e-206	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NCOHLEED_03469	2.97e-140	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NCOHLEED_03470	3.04e-174	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NCOHLEED_03471	2.58e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NCOHLEED_03472	2.44e-147	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
NCOHLEED_03473	7.44e-168	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Psort location CytoplasmicMembrane, score 7.88
NCOHLEED_03474	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NCOHLEED_03476	1.07e-286	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NCOHLEED_03477	3.38e-109	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
NCOHLEED_03478	7.26e-285	kbl	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
NCOHLEED_03479	3.16e-231	ltd	-	-	M	-	-	-	NAD dependent epimerase dehydratase family
NCOHLEED_03480	9.18e-206	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03481	1.03e-241	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NCOHLEED_03482	2.99e-176	lipB	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_03483	0.0	-	-	-	S	-	-	-	COG NOG25407 non supervised orthologous group
NCOHLEED_03484	1.72e-86	-	-	-	L	-	-	-	COG NOG19098 non supervised orthologous group
NCOHLEED_03485	1.63e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NCOHLEED_03486	3.29e-186	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III epsilon subunit and related 3'-5'
NCOHLEED_03487	6.32e-293	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NCOHLEED_03488	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NCOHLEED_03489	2.8e-173	trmH	2.1.1.185	-	J	ko:K03218,ko:K03437	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NCOHLEED_03490	0.0	-	-	-	O	-	-	-	COG COG0457 FOG TPR repeat
NCOHLEED_03491	2.08e-79	ridA	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
NCOHLEED_03492	5.32e-305	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Folylpolyglutamate synthase
NCOHLEED_03493	0.0	ybeZ_1	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
NCOHLEED_03494	0.0	wbpM	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
NCOHLEED_03495	1.9e-231	preA	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
NCOHLEED_03496	2.51e-159	yggS	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NCOHLEED_03497	8.08e-105	-	-	-	S	-	-	-	COG NOG14445 non supervised orthologous group
NCOHLEED_03498	7.14e-117	-	-	-	K	-	-	-	Transcription termination factor nusG
NCOHLEED_03499	2.48e-111	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03500	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03501	9.11e-237	-	-	-	M	-	-	-	TupA-like ATPgrasp
NCOHLEED_03502	4.76e-316	-	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NCOHLEED_03503	7.9e-246	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NCOHLEED_03504	1.66e-291	-	-	-	S	-	-	-	Glycosyl transferase, family 2
NCOHLEED_03505	1.57e-166	icaB	-	-	G	ko:K21478	-	ko00000,ko01000	polysaccharide deacetylase
NCOHLEED_03506	4.74e-267	-	-	-	-	-	-	-	-
NCOHLEED_03507	2.08e-298	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_03508	2.54e-244	-	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_03509	6.6e-255	-	5.1.3.2	-	M	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Polysaccharide biosynthesis protein
NCOHLEED_03510	2.62e-285	-	1.1.1.367	-	GM	ko:K19068	-	ko00000,ko01000	NAD dependent epimerase dehydratase family
NCOHLEED_03511	4.59e-292	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
NCOHLEED_03512	1.38e-298	wbuB	-	-	M	-	-	-	Glycosyl transferases group 1
NCOHLEED_03513	2.54e-145	pglC	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03514	4.65e-129	-	-	-	S	-	-	-	maltose O-acetyltransferase activity
NCOHLEED_03515	3.1e-311	pglE	-	-	E	-	-	-	Belongs to the DegT DnrJ EryC1 family
NCOHLEED_03516	5.29e-131	-	-	-	L	-	-	-	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
NCOHLEED_03517	4.71e-135	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03518	2.45e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NCOHLEED_03519	1.07e-151	dedA	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03520	3.8e-309	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03521	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glutamine--tRNA ligase
NCOHLEED_03522	6.29e-183	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	COG0226 ABC-type phosphate transport system, periplasmic component
NCOHLEED_03523	9.6e-269	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NCOHLEED_03524	7.99e-193	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03525	6.61e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NCOHLEED_03526	2.37e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NCOHLEED_03527	1.21e-142	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	COG0307 Riboflavin synthase alpha chain
NCOHLEED_03528	1.75e-07	-	-	-	C	-	-	-	Nitroreductase family
NCOHLEED_03529	1.13e-308	yihY	-	-	S	ko:K07058	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03530	1.13e-309	ykfC	-	-	M	-	-	-	NlpC P60 family protein
NCOHLEED_03531	2.33e-283	ykfB	5.1.1.20, 5.1.1.3	-	M	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the mandelate racemase muconate lactonizing enzyme family
NCOHLEED_03532	0.0	-	-	-	E	-	-	-	Transglutaminase-like
NCOHLEED_03533	0.0	htrA	-	-	O	-	-	-	Psort location Periplasmic, score
NCOHLEED_03534	1.27e-189	rpoD	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NCOHLEED_03535	3.64e-86	-	-	-	S	-	-	-	COG NOG31446 non supervised orthologous group
NCOHLEED_03536	4.67e-195	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
NCOHLEED_03537	0.0	cdr	-	-	P	-	-	-	Belongs to the sulfur carrier protein TusA family
NCOHLEED_03538	1.14e-71	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NCOHLEED_03539	0.0	fkp	-	-	S	-	-	-	GHMP kinase, N-terminal domain protein
NCOHLEED_03540	6.46e-116	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NCOHLEED_03541	3.96e-89	-	-	-	S	-	-	-	COG NOG32209 non supervised orthologous group
NCOHLEED_03542	1.99e-200	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
NCOHLEED_03543	1.28e-164	-	-	-	-	-	-	-	-
NCOHLEED_03544	1.23e-161	-	-	-	-	-	-	-	-
NCOHLEED_03545	9.14e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NCOHLEED_03546	4.92e-266	-	-	-	K	-	-	-	COG NOG25837 non supervised orthologous group
NCOHLEED_03547	4.13e-138	-	-	-	S	-	-	-	COG NOG28799 non supervised orthologous group
NCOHLEED_03548	1.25e-163	-	-	-	S	-	-	-	COG NOG28261 non supervised orthologous group
NCOHLEED_03549	1.09e-221	fabK	1.3.1.9	-	C	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	related to 2-nitropropane dioxygenase
NCOHLEED_03550	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03551	5.79e-172	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03552	7.72e-229	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NCOHLEED_03553	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
NCOHLEED_03554	2.87e-288	-	-	-	P	-	-	-	Transporter, major facilitator family protein
NCOHLEED_03555	7.51e-262	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
NCOHLEED_03556	0.0	-	-	-	M	-	-	-	Peptidase, M23 family
NCOHLEED_03557	0.0	-	-	-	M	-	-	-	Dipeptidase
NCOHLEED_03558	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
NCOHLEED_03559	4.21e-204	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	COG COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
NCOHLEED_03560	1.54e-145	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03561	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NCOHLEED_03562	3.47e-113	-	-	-	K	ko:K14623	-	ko00000,ko03400	BRO family, N-terminal domain
NCOHLEED_03563	1.07e-209	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NCOHLEED_03564	1.28e-71	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NCOHLEED_03565	0.0	ravA_1	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NCOHLEED_03566	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03567	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
NCOHLEED_03568	0.0	-	-	-	S	ko:K07079	-	ko00000	of the aldo keto reductase family
NCOHLEED_03569	0.0	yccM	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03570	8.71e-128	ywqN	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03571	0.0	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NCOHLEED_03572	1.96e-108	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NCOHLEED_03573	8.32e-226	lytG	-	-	MNU	-	-	-	COG1705 Muramidase (flagellum-specific)
NCOHLEED_03574	1.06e-278	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
NCOHLEED_03575	2.91e-311	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system permease component
NCOHLEED_03576	4.71e-316	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03577	7.43e-152	ytrE_3	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 7.88
NCOHLEED_03578	1.25e-302	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system permease component
NCOHLEED_03579	1e-310	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
NCOHLEED_03580	1.68e-132	-	-	-	S	-	-	-	COG NOG30399 non supervised orthologous group
NCOHLEED_03581	1.48e-305	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03582	1.57e-299	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
NCOHLEED_03583	3.63e-288	-	-	-	V	-	-	-	MacB-like periplasmic core domain
NCOHLEED_03584	7.87e-306	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NCOHLEED_03585	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03586	8.05e-297	-	-	-	G	-	-	-	COG2407 L-fucose isomerase and related
NCOHLEED_03587	1.27e-292	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
NCOHLEED_03588	1.55e-291	lolE_1	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4591 ABC-type transport system, involved in lipoprotein release, permease component
NCOHLEED_03589	8.48e-286	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NCOHLEED_03590	1.52e-157	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NCOHLEED_03591	4e-188	bioC	2.1.1.197, 3.1.1.85	-	H	ko:K02169,ko:K09789	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway
NCOHLEED_03592	8.77e-173	-	3.1.1.85	-	S	ko:K09789	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Protein of unknown function (DUF452)
NCOHLEED_03593	4.54e-284	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	COG COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
NCOHLEED_03594	0.0	bioA	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a
NCOHLEED_03595	3.97e-112	-	-	-	-	-	-	-	-
NCOHLEED_03596	9.94e-14	-	-	-	-	-	-	-	-
NCOHLEED_03597	0.0	-	-	-	S	-	-	-	COG NOG28036 non supervised orthologous group
NCOHLEED_03598	1.37e-94	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03599	6.9e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
NCOHLEED_03600	3.52e-158	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03601	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NCOHLEED_03602	3.42e-107	-	-	-	L	-	-	-	DNA-binding protein
NCOHLEED_03603	1.79e-06	-	-	-	-	-	-	-	-
NCOHLEED_03604	1.62e-119	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	COG COG3023 Negative regulator of beta-lactamase expression
NCOHLEED_03607	5.7e-263	-	2.4.1.348	GT4	M	ko:K12995	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase 4-like
NCOHLEED_03608	2.77e-58	-	-	-	I	-	-	-	Acyltransferase family
NCOHLEED_03609	0.000131	csaB	-	-	M	-	-	-	Polysaccharide pyruvyl transferase
NCOHLEED_03610	3.92e-37	-	-	-	M	-	-	-	Glycosyltransferase Family 4
NCOHLEED_03611	2.52e-32	-	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
NCOHLEED_03612	3.53e-78	-	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
NCOHLEED_03613	1.17e-60	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NCOHLEED_03614	3.59e-13	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NCOHLEED_03616	0.0	-	-	-	L	-	-	-	COG NOG25561 non supervised orthologous group
NCOHLEED_03617	6.11e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
NCOHLEED_03618	1.13e-103	-	-	-	L	-	-	-	regulation of translation
NCOHLEED_03619	1.04e-105	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_03620	4.96e-152	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
NCOHLEED_03621	4.87e-142	neuB	2.5.1.101, 2.5.1.97	-	M	ko:K15898,ko:K18430	ko00520,map00520	ko00000,ko00001,ko01000	NeuB family
NCOHLEED_03622	3.73e-76	-	-	-	S	-	-	-	transferase activity, transferring acyl groups
NCOHLEED_03623	1.1e-135	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NCOHLEED_03624	1.57e-208	-	-	-	IQ	-	-	-	AMP-binding enzyme C-terminal domain
NCOHLEED_03625	1.76e-30	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
NCOHLEED_03626	7.32e-159	pseG	-	-	M	-	-	-	COG3980 Spore coat polysaccharide biosynthesis protein
NCOHLEED_03627	6.91e-61	-	-	-	S	-	-	-	Protein of unknown function DUF86
NCOHLEED_03628	1.17e-61	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
NCOHLEED_03629	3.41e-160	pseF	-	-	M	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_03630	4.78e-295	pseC	-	-	E	-	-	-	Belongs to the DegT DnrJ EryC1 family
NCOHLEED_03631	3.49e-246	pseB	4.2.1.115	-	M	ko:K15894	ko00520,map00520	ko00000,ko00001,ko01000	Male sterility protein
NCOHLEED_03632	7.36e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03633	2.6e-124	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03634	8.17e-246	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03635	2.31e-73	-	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
NCOHLEED_03636	6.61e-277	hydF	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03637	0.0	hydG	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Iron-only hydrogenase maturation rSAM protein HydG
NCOHLEED_03638	7.41e-254	hydE	2.8.1.6	-	C	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Iron-only hydrogenase maturation rSAM protein HydE
NCOHLEED_03639	0.0	-	-	-	C	-	-	-	4Fe-4S binding domain protein
NCOHLEED_03640	8.91e-121	paiA	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03641	0.0	-	-	-	P	ko:K03305	-	ko00000	amino acid peptide transporter
NCOHLEED_03642	7.13e-115	ybaK	-	-	H	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NCOHLEED_03643	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NCOHLEED_03644	0.0	lysM	-	-	M	-	-	-	LysM domain
NCOHLEED_03645	1.34e-169	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
NCOHLEED_03646	1.91e-98	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03647	1.38e-71	rpoZ	-	-	S	-	-	-	COG NOG14434 non supervised orthologous group
NCOHLEED_03648	7.14e-189	yfiO	-	-	S	ko:K05807	-	ko00000,ko02000	outer membrane assembly lipoprotein YfiO
NCOHLEED_03649	5.03e-95	-	-	-	S	-	-	-	ACT domain protein
NCOHLEED_03650	0.0	-	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NCOHLEED_03651	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NCOHLEED_03652	6.12e-257	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NCOHLEED_03653	0.0	addA	-	-	L	-	-	-	Belongs to the helicase family. UvrD subfamily
NCOHLEED_03654	0.0	-	-	-	L	-	-	-	DNA-dependent ATPase I and helicase II
NCOHLEED_03655	9.13e-262	pleD	2.7.13.3	-	T	ko:K11527	-	ko00000,ko01000,ko01001,ko02022	Response regulator receiver domain protein
NCOHLEED_03656	4.49e-232	-	4.1.1.35	-	GM	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
NCOHLEED_03657	1.69e-124	ibrB	-	-	K	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_03658	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase family
NCOHLEED_03659	1.49e-89	-	-	-	S	-	-	-	COG NOG32529 non supervised orthologous group
NCOHLEED_03660	5.95e-117	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
NCOHLEED_03661	1.4e-117	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
NCOHLEED_03662	4.69e-287	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	L-fucose H symporter permease
NCOHLEED_03663	7.05e-216	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family) K00567
NCOHLEED_03664	1.34e-98	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase like
NCOHLEED_03665	1.43e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NCOHLEED_03666	0.0	-	-	-	V	-	-	-	MATE efflux family protein
NCOHLEED_03667	2.07e-150	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03668	2.11e-132	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
NCOHLEED_03669	3.38e-116	-	-	-	I	-	-	-	sulfurtransferase activity
NCOHLEED_03670	3.31e-198	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	protein contains double-stranded beta-helix domain
NCOHLEED_03671	4.19e-238	-	-	-	S	-	-	-	Flavin reductase like domain
NCOHLEED_03673	0.0	alaC	-	-	E	-	-	-	Aminotransferase, class I II
NCOHLEED_03674	0.0	-	-	-	S	-	-	-	COG NOG26858 non supervised orthologous group
NCOHLEED_03675	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
NCOHLEED_03676	3.43e-144	-	-	-	K	ko:K07735	-	ko00000,ko03000	Belongs to the UPF0301 (AlgH) family
NCOHLEED_03677	1.27e-127	speG	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase, gnat family
NCOHLEED_03678	5.07e-98	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03679	3.58e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NCOHLEED_03681	2e-142	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NCOHLEED_03682	1.06e-126	-	-	-	S	-	-	-	COG NOG28221 non supervised orthologous group
NCOHLEED_03689	2.42e-285	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
NCOHLEED_03690	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NCOHLEED_03691	1.93e-151	sodB	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NCOHLEED_03692	9.2e-148	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase TENI
NCOHLEED_03693	5.63e-197	-	-	-	T	-	-	-	histidine kinase DNA gyrase B
NCOHLEED_03694	2.34e-305	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_03695	2.78e-82	-	-	-	S	-	-	-	COG3943, virulence protein
NCOHLEED_03696	8.69e-68	-	-	-	S	-	-	-	DNA binding domain, excisionase family
NCOHLEED_03697	3.71e-63	-	-	-	S	-	-	-	Helix-turn-helix domain
NCOHLEED_03698	4.95e-76	-	-	-	S	-	-	-	DNA binding domain, excisionase family
NCOHLEED_03699	7.79e-78	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NCOHLEED_03700	0.0	-	-	-	S	-	-	-	COG NOG09947 non supervised orthologous group
NCOHLEED_03701	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
NCOHLEED_03702	1.11e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03703	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NCOHLEED_03704	0.0	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
NCOHLEED_03705	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NCOHLEED_03706	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	N-terminal domain of reverse transcriptase
NCOHLEED_03707	2.1e-288	-	-	-	KL	-	-	-	helicase C-terminal domain protein
NCOHLEED_03708	0.0	tetP	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation Factor G, domain II
NCOHLEED_03709	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_03710	0.0	zraR	-	-	T	ko:K07713	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Sigma-54 interaction domain protein
NCOHLEED_03711	1.83e-101	-	-	-	H	-	-	-	dihydrofolate reductase family protein K00287
NCOHLEED_03712	6.37e-140	rteC	-	-	S	-	-	-	RteC protein
NCOHLEED_03713	3.35e-269	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score 8.96
NCOHLEED_03714	0.0	-	-	-	S	-	-	-	KAP family P-loop domain
NCOHLEED_03715	0.0	-	-	-	U	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03716	5.69e-299	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
NCOHLEED_03717	6.34e-94	-	-	-	-	-	-	-	-
NCOHLEED_03718	5.35e-179	-	-	-	D	-	-	-	COG NOG26689 non supervised orthologous group
NCOHLEED_03719	7.32e-95	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03720	5e-78	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03721	2.02e-163	-	-	-	S	-	-	-	Conjugal transfer protein traD
NCOHLEED_03722	2.18e-63	-	-	-	S	-	-	-	Conjugative transposon protein TraE
NCOHLEED_03723	7.4e-71	-	-	-	S	-	-	-	Conjugative transposon protein TraF
NCOHLEED_03724	0.0	-	-	-	U	-	-	-	conjugation system ATPase, TraG family
NCOHLEED_03725	3.1e-71	-	-	-	-	-	-	-	-
NCOHLEED_03726	0.0	-	-	-	L	-	-	-	COG COG3344 Retron-type reverse transcriptase
NCOHLEED_03727	3.93e-214	-	-	-	U	-	-	-	conjugation system ATPase, TraG family
NCOHLEED_03728	2.82e-87	-	-	-	S	-	-	-	COG NOG30362 non supervised orthologous group
NCOHLEED_03729	2.15e-145	-	-	-	U	-	-	-	COG NOG09946 non supervised orthologous group
NCOHLEED_03730	4.77e-225	traJ	-	-	S	-	-	-	Conjugative transposon TraJ protein
NCOHLEED_03731	2.51e-143	-	-	-	U	-	-	-	Conjugative transposon TraK protein
NCOHLEED_03732	4.7e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3989)
NCOHLEED_03733	1.27e-306	traM	-	-	S	-	-	-	Conjugative transposon TraM protein
NCOHLEED_03734	9.5e-238	-	-	-	U	-	-	-	Conjugative transposon TraN protein
NCOHLEED_03735	1.95e-139	-	-	-	S	-	-	-	COG NOG19079 non supervised orthologous group
NCOHLEED_03736	6.05e-220	-	-	-	L	-	-	-	CHC2 zinc finger domain protein
NCOHLEED_03737	2.01e-118	-	-	-	S	-	-	-	COG NOG28378 non supervised orthologous group
NCOHLEED_03738	1.54e-74	-	3.2.1.17	-	S	ko:K01185	-	ko00000,ko01000	lysozyme
NCOHLEED_03739	5.16e-103	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NCOHLEED_03740	4.16e-113	-	-	-	L	-	-	-	Phage integrase family
NCOHLEED_03741	3.61e-78	-	-	-	L	-	-	-	Phage integrase family
NCOHLEED_03742	2.03e-40	-	3.2.1.17	-	S	ko:K01185	-	ko00000,ko01000	lysozyme
NCOHLEED_03743	3.18e-50	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NCOHLEED_03744	1.9e-68	-	-	-	-	-	-	-	-
NCOHLEED_03745	1.29e-53	-	-	-	-	-	-	-	-
NCOHLEED_03746	7.72e-51	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03747	6.23e-56	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03748	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03749	4.17e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03750	6.56e-48	-	-	-	S	-	-	-	COG NOG33922 non supervised orthologous group
NCOHLEED_03751	4.22e-41	-	-	-	-	-	-	-	-
NCOHLEED_03752	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
NCOHLEED_03753	0.0	rumA	2.1.1.190	-	H	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NCOHLEED_03754	2.67e-220	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NCOHLEED_03755	1.63e-100	-	-	-	-	-	-	-	-
NCOHLEED_03756	3.25e-106	-	-	-	-	-	-	-	-
NCOHLEED_03757	2.37e-271	araJ	-	-	EGP	ko:K08156	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03758	1.61e-225	lacX	-	-	G	-	-	-	COG COG2017 Galactose mutarotase and related enzymes
NCOHLEED_03759	8e-79	-	-	-	KT	-	-	-	PAS domain
NCOHLEED_03760	9.23e-254	-	-	-	-	-	-	-	-
NCOHLEED_03761	3.31e-149	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03762	7.12e-296	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NCOHLEED_03763	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
NCOHLEED_03764	2.01e-210	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
NCOHLEED_03765	5.28e-281	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
NCOHLEED_03766	5.33e-312	nqrF	1.6.5.8	-	C	ko:K00351	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
NCOHLEED_03767	5.94e-122	nqrE	1.6.5.8	-	C	ko:K00350	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NCOHLEED_03768	1.31e-142	nqrD	1.6.5.8	-	C	ko:K00349	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NCOHLEED_03769	1.97e-160	nqrC	1.6.5.8	-	C	ko:K00348	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NCOHLEED_03770	3.52e-273	nqrB	1.6.5.8	-	C	ko:K00347	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NCOHLEED_03771	0.0	nqrA	1.6.5.8	-	C	ko:K00346	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NCOHLEED_03772	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NCOHLEED_03773	7.15e-299	-	-	-	M	-	-	-	COG NOG26016 non supervised orthologous group
NCOHLEED_03774	7.02e-288	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
NCOHLEED_03775	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
NCOHLEED_03776	0.0	-	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG5016 Pyruvate oxaloacetate carboxyltransferase
NCOHLEED_03777	3.34e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NCOHLEED_03778	0.0	-	-	-	S	-	-	-	Peptidase M16 inactive domain
NCOHLEED_03779	6.65e-149	yadS	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NCOHLEED_03780	2.14e-259	wecB	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NCOHLEED_03781	0.0	-	-	-	M	-	-	-	COG NOG06397 non supervised orthologous group
NCOHLEED_03782	7.3e-306	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NCOHLEED_03783	2.7e-232	hprA	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCOHLEED_03784	4.73e-266	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family protein
NCOHLEED_03785	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
NCOHLEED_03786	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NCOHLEED_03787	1.11e-299	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	) H( ) antiporter that extrudes sodium in exchange for external protons
NCOHLEED_03788	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NCOHLEED_03789	2.09e-41	-	-	-	S	-	-	-	COG NOG33517 non supervised orthologous group
NCOHLEED_03790	8.08e-105	-	-	-	S	-	-	-	COG NOG16874 non supervised orthologous group
NCOHLEED_03791	9.51e-194	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score 9.97
NCOHLEED_03792	1.73e-287	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family
NCOHLEED_03793	1.91e-55	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NCOHLEED_03794	1.39e-177	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NCOHLEED_03795	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
NCOHLEED_03796	8.9e-11	-	-	-	-	-	-	-	-
NCOHLEED_03797	9.2e-110	-	-	-	L	-	-	-	DNA-binding protein
NCOHLEED_03798	2.28e-152	wcgX	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Psort location CytoplasmicMembrane, score 10.00