ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HKAHPFCC_00001 2.66e-117 entB - - Q - - - Isochorismatase family
HKAHPFCC_00002 0.0 - 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 EcoEI R protein C-terminal
HKAHPFCC_00003 4.95e-269 - - - V - - - Type I restriction modification DNA specificity domain
HKAHPFCC_00004 1.68e-228 - - - L - - - Belongs to the 'phage' integrase family
HKAHPFCC_00005 7.33e-248 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HKAHPFCC_00006 0.0 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HKAHPFCC_00007 1.83e-302 - - - - - - - -
HKAHPFCC_00008 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKAHPFCC_00010 5.72e-239 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HKAHPFCC_00011 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKAHPFCC_00012 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKAHPFCC_00013 9.59e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKAHPFCC_00014 1.91e-261 camS - - S - - - sex pheromone
HKAHPFCC_00015 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKAHPFCC_00016 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HKAHPFCC_00017 3.24e-272 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKAHPFCC_00018 2.36e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKAHPFCC_00019 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HKAHPFCC_00020 7.72e-181 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HKAHPFCC_00021 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HKAHPFCC_00022 2.27e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKAHPFCC_00023 7.76e-185 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKAHPFCC_00024 3.51e-182 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKAHPFCC_00025 1.1e-200 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKAHPFCC_00026 2.21e-189 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKAHPFCC_00027 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HKAHPFCC_00028 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKAHPFCC_00029 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKAHPFCC_00030 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKAHPFCC_00031 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HKAHPFCC_00032 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKAHPFCC_00033 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKAHPFCC_00034 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKAHPFCC_00035 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HKAHPFCC_00036 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HKAHPFCC_00037 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKAHPFCC_00038 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKAHPFCC_00039 2.6e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKAHPFCC_00040 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKAHPFCC_00041 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKAHPFCC_00042 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKAHPFCC_00043 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKAHPFCC_00044 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKAHPFCC_00045 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKAHPFCC_00046 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HKAHPFCC_00047 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKAHPFCC_00048 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKAHPFCC_00049 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKAHPFCC_00050 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKAHPFCC_00051 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKAHPFCC_00052 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKAHPFCC_00053 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HKAHPFCC_00054 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKAHPFCC_00055 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HKAHPFCC_00056 1.1e-255 - - - L - - - Transposase
HKAHPFCC_00057 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKAHPFCC_00058 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKAHPFCC_00059 3.56e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKAHPFCC_00060 1.44e-155 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HKAHPFCC_00061 3.31e-263 - - - - - - - -
HKAHPFCC_00062 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKAHPFCC_00063 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKAHPFCC_00064 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
HKAHPFCC_00065 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKAHPFCC_00066 1.39e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HKAHPFCC_00067 1.8e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HKAHPFCC_00068 7.53e-191 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HKAHPFCC_00074 7.78e-150 dgk2 - - F - - - deoxynucleoside kinase
HKAHPFCC_00077 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HKAHPFCC_00078 2.01e-206 - - - S - - - Calcineurin-like phosphoesterase
HKAHPFCC_00081 5.92e-150 - - - - - - - -
HKAHPFCC_00082 0.0 - - - EGP - - - Major Facilitator
HKAHPFCC_00083 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
HKAHPFCC_00084 5.9e-170 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HKAHPFCC_00085 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HKAHPFCC_00086 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKAHPFCC_00087 1.84e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKAHPFCC_00088 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HKAHPFCC_00089 2e-112 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HKAHPFCC_00091 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKAHPFCC_00092 9.89e-240 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HKAHPFCC_00093 0.0 - - - S - - - Bacterial membrane protein, YfhO
HKAHPFCC_00094 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKAHPFCC_00095 7.63e-217 - - - I - - - alpha/beta hydrolase fold
HKAHPFCC_00096 4.46e-276 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HKAHPFCC_00097 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKAHPFCC_00098 1.75e-173 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_00099 3.01e-181 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HKAHPFCC_00100 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HKAHPFCC_00101 2.5e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKAHPFCC_00102 1.65e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HKAHPFCC_00103 1.02e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HKAHPFCC_00104 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKAHPFCC_00105 2.54e-266 yacL - - S - - - domain protein
HKAHPFCC_00106 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HKAHPFCC_00107 2.16e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKAHPFCC_00108 1.82e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKAHPFCC_00109 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HKAHPFCC_00110 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKAHPFCC_00111 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HKAHPFCC_00112 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKAHPFCC_00113 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKAHPFCC_00114 9.63e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HKAHPFCC_00116 0.0 - - - M - - - Glycosyl transferase family group 2
HKAHPFCC_00117 4.1e-273 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKAHPFCC_00118 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKAHPFCC_00119 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKAHPFCC_00120 8.34e-65 - - - - - - - -
HKAHPFCC_00122 2.94e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKAHPFCC_00123 1.38e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
HKAHPFCC_00124 5.64e-129 - - - S - - - Protein of unknown function (DUF1700)
HKAHPFCC_00125 3.67e-176 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HKAHPFCC_00126 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HKAHPFCC_00127 1.14e-255 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKAHPFCC_00128 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKAHPFCC_00129 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HKAHPFCC_00130 6.21e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKAHPFCC_00131 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKAHPFCC_00132 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKAHPFCC_00133 4.92e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKAHPFCC_00134 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
HKAHPFCC_00135 1.11e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKAHPFCC_00136 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
HKAHPFCC_00137 2.72e-237 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HKAHPFCC_00138 6.41e-77 yabA - - L - - - Involved in initiation control of chromosome replication
HKAHPFCC_00139 9.87e-204 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKAHPFCC_00140 2.92e-183 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HKAHPFCC_00141 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HKAHPFCC_00142 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKAHPFCC_00143 1.43e-225 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HKAHPFCC_00144 1.48e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HKAHPFCC_00145 1.24e-233 - - - S - - - YSIRK type signal peptide
HKAHPFCC_00146 4.53e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKAHPFCC_00147 2.95e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HKAHPFCC_00148 1.39e-177 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_00149 1.49e-102 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HKAHPFCC_00151 3.01e-178 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKAHPFCC_00152 0.0 yhaN - - L - - - AAA domain
HKAHPFCC_00153 4.1e-295 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HKAHPFCC_00154 3.9e-79 yheA - - S - - - Belongs to the UPF0342 family
HKAHPFCC_00155 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HKAHPFCC_00156 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HKAHPFCC_00157 1.51e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HKAHPFCC_00158 4.93e-216 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HKAHPFCC_00160 1.49e-54 - - - - - - - -
HKAHPFCC_00161 4.61e-61 - - - - - - - -
HKAHPFCC_00162 5.66e-278 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HKAHPFCC_00163 8.88e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HKAHPFCC_00164 5.72e-301 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HKAHPFCC_00165 1.17e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HKAHPFCC_00166 4.05e-124 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKAHPFCC_00167 1.22e-74 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKAHPFCC_00168 5.82e-96 - - - - - - - -
HKAHPFCC_00170 9.17e-59 - - - - - - - -
HKAHPFCC_00171 2.21e-155 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKAHPFCC_00172 1.52e-43 - - - - - - - -
HKAHPFCC_00173 8.45e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKAHPFCC_00174 2.63e-240 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HKAHPFCC_00175 5.33e-147 - - - - - - - -
HKAHPFCC_00176 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
HKAHPFCC_00177 9.46e-242 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKAHPFCC_00178 5.35e-113 - - - T - - - Belongs to the universal stress protein A family
HKAHPFCC_00179 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HKAHPFCC_00180 9.07e-199 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKAHPFCC_00181 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HKAHPFCC_00182 8.74e-57 - - - - - - - -
HKAHPFCC_00183 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HKAHPFCC_00184 9.47e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKAHPFCC_00185 4.49e-130 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HKAHPFCC_00186 7.96e-41 - - - - - - - -
HKAHPFCC_00187 0.0 - - - EGP - - - Major Facilitator
HKAHPFCC_00188 1.25e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HKAHPFCC_00189 8.53e-304 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HKAHPFCC_00190 2.01e-134 - - - V - - - VanZ like family
HKAHPFCC_00191 7.03e-33 - - - - - - - -
HKAHPFCC_00192 2.05e-110 - - - S - - - Short repeat of unknown function (DUF308)
HKAHPFCC_00193 7.91e-104 - - - S - - - Psort location Cytoplasmic, score
HKAHPFCC_00194 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HKAHPFCC_00195 4.63e-101 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HKAHPFCC_00196 2.42e-201 yeaE - - S - - - Aldo keto
HKAHPFCC_00197 2.29e-309 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HKAHPFCC_00198 4.87e-299 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HKAHPFCC_00199 4.36e-194 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HKAHPFCC_00200 2.13e-142 - - - M - - - LysM domain protein
HKAHPFCC_00201 0.0 - - - EP - - - Psort location Cytoplasmic, score
HKAHPFCC_00202 1.32e-131 - - - M - - - LysM domain protein
HKAHPFCC_00203 7.9e-214 - - - O - - - Uncharacterized protein family (UPF0051)
HKAHPFCC_00204 1.37e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKAHPFCC_00205 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HKAHPFCC_00206 9.83e-316 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HKAHPFCC_00207 9.73e-132 - - - K - - - Acetyltransferase (GNAT) domain
HKAHPFCC_00215 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
HKAHPFCC_00216 4.03e-163 pgm3 - - G - - - phosphoglycerate mutase family
HKAHPFCC_00217 1.77e-56 - - - - - - - -
HKAHPFCC_00218 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKAHPFCC_00219 6.52e-270 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
HKAHPFCC_00220 3.54e-181 - - - S - - - Alpha beta hydrolase
HKAHPFCC_00221 6.17e-281 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HKAHPFCC_00222 3.48e-134 - - - - - - - -
HKAHPFCC_00224 5.09e-162 - - - M - - - ErfK YbiS YcfS YnhG
HKAHPFCC_00225 1.4e-120 - - - S - - - Putative peptidoglycan binding domain
HKAHPFCC_00226 1.25e-54 - - - S - - - Putative peptidoglycan binding domain
HKAHPFCC_00227 1.34e-145 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HKAHPFCC_00228 1.8e-115 - - - - - - - -
HKAHPFCC_00229 1.38e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HKAHPFCC_00230 2.7e-277 yttB - - EGP - - - Major Facilitator
HKAHPFCC_00231 1.52e-148 - - - - - - - -
HKAHPFCC_00232 2.6e-33 - - - - - - - -
HKAHPFCC_00233 1.38e-223 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HKAHPFCC_00234 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKAHPFCC_00235 2.75e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HKAHPFCC_00236 2.89e-51 - - - - - - - -
HKAHPFCC_00237 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_00238 2.58e-156 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_00239 2.5e-236 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HKAHPFCC_00240 5.75e-117 - - - K - - - transcriptional regulator (TetR family)
HKAHPFCC_00241 9.96e-244 - - - E - - - Zinc-binding dehydrogenase
HKAHPFCC_00242 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HKAHPFCC_00243 2.09e-86 - - - - - - - -
HKAHPFCC_00244 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKAHPFCC_00246 5.75e-117 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HKAHPFCC_00247 1.36e-141 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HKAHPFCC_00248 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HKAHPFCC_00249 4.54e-316 - - - E ko:K03294 - ko00000 amino acid
HKAHPFCC_00250 1.46e-236 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKAHPFCC_00252 2.33e-39 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HKAHPFCC_00253 9.7e-06 - - - S - - - Protein of unknown function (DUF3278)
HKAHPFCC_00254 2.61e-283 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HKAHPFCC_00255 5.47e-55 - - - S - - - Cytochrome B5
HKAHPFCC_00256 8.47e-08 - - - S - - - Cytochrome B5
HKAHPFCC_00257 2.3e-52 - - - S - - - Cytochrome B5
HKAHPFCC_00258 7.65e-101 - - - S ko:K02348 - ko00000 Gnat family
HKAHPFCC_00259 6.67e-158 - - - GM - - - NmrA-like family
HKAHPFCC_00260 2.74e-69 ydeP - - K - - - Transcriptional regulator, HxlR family
HKAHPFCC_00261 1.41e-141 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HKAHPFCC_00262 1.85e-108 - - - K - - - Transcriptional regulator, HxlR family
HKAHPFCC_00263 6.82e-309 - - - - - - - -
HKAHPFCC_00264 2.28e-270 - - - EGP - - - Major Facilitator Superfamily
HKAHPFCC_00265 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HKAHPFCC_00266 6.4e-149 - - - GM - - - NAD dependent epimerase dehydratase family protein
HKAHPFCC_00267 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HKAHPFCC_00268 1.37e-123 - - - S - - - ECF transporter, substrate-specific component
HKAHPFCC_00269 1.23e-253 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HKAHPFCC_00270 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HKAHPFCC_00271 3.29e-162 - - - T - - - Putative diguanylate phosphodiesterase
HKAHPFCC_00272 1.75e-263 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
HKAHPFCC_00273 7.04e-118 - - - - - - - -
HKAHPFCC_00274 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HKAHPFCC_00275 1.07e-205 - - - T - - - EAL domain
HKAHPFCC_00276 0.0 - - - M - - - Rib/alpha-like repeat
HKAHPFCC_00277 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKAHPFCC_00278 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKAHPFCC_00279 3.99e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_00280 2.25e-288 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HKAHPFCC_00281 1.69e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
HKAHPFCC_00282 2.47e-220 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HKAHPFCC_00283 1.08e-210 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HKAHPFCC_00284 9.71e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HKAHPFCC_00285 3.57e-198 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HKAHPFCC_00286 8.34e-180 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HKAHPFCC_00287 1.68e-198 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HKAHPFCC_00288 8.24e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HKAHPFCC_00289 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKAHPFCC_00290 6.3e-175 - - - S - - - Protein of unknown function (DUF1129)
HKAHPFCC_00291 5.64e-153 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKAHPFCC_00292 6.87e-300 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKAHPFCC_00293 5.15e-306 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HKAHPFCC_00294 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HKAHPFCC_00295 5.59e-221 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HKAHPFCC_00296 1.47e-265 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKAHPFCC_00297 9.76e-161 vanR - - K - - - response regulator
HKAHPFCC_00298 1.36e-266 hpk31 - - T - - - Histidine kinase
HKAHPFCC_00299 6.03e-196 - - - E - - - AzlC protein
HKAHPFCC_00300 4.05e-70 - - - S - - - branched-chain amino acid
HKAHPFCC_00301 1.3e-156 - - - K ko:K09681 - ko00000,ko03000 DNA-binding transcription factor activity
HKAHPFCC_00302 1.56e-20 - - - K - - - LysR substrate binding domain
HKAHPFCC_00303 1.81e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HKAHPFCC_00304 3.19e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKAHPFCC_00305 2.77e-220 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKAHPFCC_00306 1.96e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKAHPFCC_00307 6.66e-151 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKAHPFCC_00308 1.4e-152 - - - S - - - Haloacid dehalogenase-like hydrolase
HKAHPFCC_00309 1.4e-302 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HKAHPFCC_00310 5.53e-223 ydbI - - K - - - AI-2E family transporter
HKAHPFCC_00311 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HKAHPFCC_00312 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HKAHPFCC_00313 4.32e-173 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
HKAHPFCC_00314 8.95e-110 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKAHPFCC_00315 1.75e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKAHPFCC_00316 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKAHPFCC_00317 2.7e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HKAHPFCC_00318 1.34e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKAHPFCC_00319 1.19e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKAHPFCC_00320 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKAHPFCC_00321 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKAHPFCC_00322 8.29e-252 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HKAHPFCC_00323 4.09e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKAHPFCC_00324 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HKAHPFCC_00325 4.44e-314 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HKAHPFCC_00326 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKAHPFCC_00327 4.86e-237 - - - - - - - -
HKAHPFCC_00328 2.97e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKAHPFCC_00329 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HKAHPFCC_00330 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKAHPFCC_00332 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKAHPFCC_00333 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKAHPFCC_00334 3.5e-112 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HKAHPFCC_00335 0.0 - - - E - - - amino acid
HKAHPFCC_00336 0.0 ydaO - - E - - - amino acid
HKAHPFCC_00337 2.63e-53 - - - - - - - -
HKAHPFCC_00338 3.07e-89 - - - K - - - Transcriptional regulator
HKAHPFCC_00339 0.0 - - - EGP - - - Major Facilitator
HKAHPFCC_00340 1.4e-146 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HKAHPFCC_00341 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HKAHPFCC_00342 1.4e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HKAHPFCC_00343 3.01e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKAHPFCC_00344 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKAHPFCC_00345 4.72e-240 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKAHPFCC_00346 3.65e-67 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
HKAHPFCC_00347 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HKAHPFCC_00348 1.38e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKAHPFCC_00349 4.38e-205 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKAHPFCC_00350 5.93e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HKAHPFCC_00351 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HKAHPFCC_00352 4.49e-178 lutC - - S ko:K00782 - ko00000 LUD domain
HKAHPFCC_00353 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
HKAHPFCC_00354 2.37e-216 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
HKAHPFCC_00355 2.04e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKAHPFCC_00356 1.45e-281 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HKAHPFCC_00357 5.33e-211 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
HKAHPFCC_00358 5.98e-116 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HKAHPFCC_00359 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKAHPFCC_00360 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HKAHPFCC_00361 2.12e-19 - - - - - - - -
HKAHPFCC_00362 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKAHPFCC_00363 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKAHPFCC_00364 9.18e-317 steT - - E ko:K03294 - ko00000 amino acid
HKAHPFCC_00365 3.42e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HKAHPFCC_00366 6.97e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HKAHPFCC_00367 6.77e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HKAHPFCC_00369 1.83e-21 - - - - - - - -
HKAHPFCC_00370 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKAHPFCC_00371 1.81e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HKAHPFCC_00372 3.56e-113 - - - F - - - NUDIX domain
HKAHPFCC_00373 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKAHPFCC_00374 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKAHPFCC_00375 1.9e-139 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKAHPFCC_00376 2.19e-218 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HKAHPFCC_00377 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKAHPFCC_00378 2.44e-210 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HKAHPFCC_00379 3.16e-184 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKAHPFCC_00380 2.53e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKAHPFCC_00381 4.62e-48 yozE - - S - - - Belongs to the UPF0346 family
HKAHPFCC_00382 2.01e-141 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HKAHPFCC_00383 1.18e-221 - - - E - - - lipolytic protein G-D-S-L family
HKAHPFCC_00384 9.45e-198 WQ51_01275 - - S - - - EDD domain protein, DegV family
HKAHPFCC_00385 2.59e-144 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HKAHPFCC_00386 4.1e-120 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKAHPFCC_00387 3.61e-247 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKAHPFCC_00388 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_00389 1.8e-289 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKAHPFCC_00390 1.64e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HKAHPFCC_00391 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKAHPFCC_00392 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HKAHPFCC_00393 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HKAHPFCC_00394 4.62e-154 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HKAHPFCC_00395 1.81e-70 - - - M - - - Lysin motif
HKAHPFCC_00396 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HKAHPFCC_00397 8.62e-252 - - - S - - - Helix-turn-helix domain
HKAHPFCC_00398 3.23e-134 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKAHPFCC_00399 2.58e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HKAHPFCC_00400 1.15e-136 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKAHPFCC_00401 1.05e-181 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKAHPFCC_00402 3.67e-86 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKAHPFCC_00403 4.23e-214 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HKAHPFCC_00404 9.26e-216 yitL - - S ko:K00243 - ko00000 S1 domain
HKAHPFCC_00405 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HKAHPFCC_00406 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HKAHPFCC_00407 5.59e-42 - - - S - - - Protein of unknown function (DUF2929)
HKAHPFCC_00408 1.72e-305 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HKAHPFCC_00409 1.93e-203 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKAHPFCC_00410 1.23e-166 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HKAHPFCC_00411 0.0 potE - - E - - - Amino Acid
HKAHPFCC_00412 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HKAHPFCC_00413 5.05e-283 arcT - - E - - - Aminotransferase
HKAHPFCC_00414 1e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HKAHPFCC_00415 1.64e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HKAHPFCC_00416 8.59e-98 gtcA - - S - - - Teichoic acid glycosylation protein
HKAHPFCC_00417 4.07e-72 - - - - - - - -
HKAHPFCC_00418 6.52e-270 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKAHPFCC_00420 3.45e-300 yfmL - - L - - - DEAD DEAH box helicase
HKAHPFCC_00421 1.31e-245 mocA - - S - - - Oxidoreductase
HKAHPFCC_00422 7.97e-82 - - - S - - - Domain of unknown function (DUF4828)
HKAHPFCC_00423 1.66e-142 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HKAHPFCC_00424 2.64e-213 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HKAHPFCC_00425 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HKAHPFCC_00426 1.32e-255 - - - S - - - Protein of unknown function (DUF3114)
HKAHPFCC_00427 3.32e-107 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HKAHPFCC_00428 1.59e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HKAHPFCC_00429 7.31e-27 - - - - - - - -
HKAHPFCC_00430 2.44e-125 - - - K - - - Acetyltransferase (GNAT) family
HKAHPFCC_00431 2.57e-103 - - - K - - - LytTr DNA-binding domain
HKAHPFCC_00432 4.56e-99 - - - S - - - Protein of unknown function (DUF3021)
HKAHPFCC_00433 1.22e-218 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
HKAHPFCC_00434 4.43e-100 XK27_00915 - - C - - - Luciferase-like monooxygenase
HKAHPFCC_00435 1.04e-168 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HKAHPFCC_00436 1.85e-109 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HKAHPFCC_00437 3.87e-161 pnb - - C - - - nitroreductase
HKAHPFCC_00438 5.22e-120 - - - - - - - -
HKAHPFCC_00439 2.89e-110 yvbK - - K - - - GNAT family
HKAHPFCC_00440 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
HKAHPFCC_00441 8.89e-269 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HKAHPFCC_00442 2.27e-62 - - - S - - - PD-(D/E)XK nuclease family transposase
HKAHPFCC_00443 3.01e-92 - - - S - - - PFAM Archaeal ATPase
HKAHPFCC_00444 5.76e-134 - - - S - - - PFAM Archaeal ATPase
HKAHPFCC_00445 0.0 XK27_08510 - - L - - - Type III restriction protein res subunit
HKAHPFCC_00446 1.6e-69 - - - - - - - -
HKAHPFCC_00447 9.52e-204 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKAHPFCC_00448 8.27e-189 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HKAHPFCC_00449 3.2e-100 - - - K - - - LytTr DNA-binding domain
HKAHPFCC_00450 9.77e-80 - - - S - - - Protein of unknown function (DUF3021)
HKAHPFCC_00452 6.17e-236 - - - L - - - Plasmid pRiA4b ORF-3-like protein
HKAHPFCC_00454 2.7e-145 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HKAHPFCC_00455 3.54e-128 dpsB - - P - - - Belongs to the Dps family
HKAHPFCC_00456 2.79e-49 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 PFAM Heavy metal transport detoxification protein
HKAHPFCC_00457 2.66e-110 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HKAHPFCC_00458 2.74e-246 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HKAHPFCC_00459 8.72e-50 - - - F - - - NUDIX domain
HKAHPFCC_00460 6.92e-184 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKAHPFCC_00461 2.03e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HKAHPFCC_00462 9.87e-300 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HKAHPFCC_00463 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKAHPFCC_00464 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKAHPFCC_00465 7.73e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HKAHPFCC_00466 3.54e-276 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HKAHPFCC_00467 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HKAHPFCC_00468 1.96e-65 ylxQ - - J - - - ribosomal protein
HKAHPFCC_00469 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKAHPFCC_00470 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKAHPFCC_00471 1.48e-216 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKAHPFCC_00472 4.14e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HKAHPFCC_00473 3.09e-85 - - - - - - - -
HKAHPFCC_00474 1.37e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKAHPFCC_00475 2.83e-118 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKAHPFCC_00476 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HKAHPFCC_00477 3.81e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKAHPFCC_00478 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKAHPFCC_00479 4.55e-288 int7 - - L - - - Belongs to the 'phage' integrase family
HKAHPFCC_00480 1.7e-182 - - - - - - - -
HKAHPFCC_00481 4.29e-18 - - - - - - - -
HKAHPFCC_00482 2.44e-99 - - - - - - - -
HKAHPFCC_00483 5.09e-107 - - - - - - - -
HKAHPFCC_00484 2.6e-14 - - - K - - - Peptidase S24-like
HKAHPFCC_00485 1.21e-30 - - - K - - - Peptidase S24-like
HKAHPFCC_00486 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKAHPFCC_00487 3.16e-258 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HKAHPFCC_00488 3.37e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HKAHPFCC_00490 3.36e-77 - - - - - - - -
HKAHPFCC_00491 2.15e-234 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HKAHPFCC_00492 1.05e-168 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKAHPFCC_00493 2.38e-72 - - - - - - - -
HKAHPFCC_00494 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKAHPFCC_00495 5.38e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKAHPFCC_00496 2.03e-218 - - - G - - - Phosphotransferase enzyme family
HKAHPFCC_00497 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKAHPFCC_00498 6.11e-44 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
HKAHPFCC_00500 2.69e-36 - - - - - - - -
HKAHPFCC_00501 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HKAHPFCC_00502 2.09e-154 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HKAHPFCC_00503 7.78e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HKAHPFCC_00504 0.0 yclK - - T - - - Histidine kinase
HKAHPFCC_00505 2.06e-176 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HKAHPFCC_00507 2.2e-110 lytE - - M - - - Lysin motif
HKAHPFCC_00508 4.88e-194 - - - S - - - Cof-like hydrolase
HKAHPFCC_00509 7.53e-104 - - - K - - - Transcriptional regulator
HKAHPFCC_00510 0.0 oatA - - I - - - Acyltransferase
HKAHPFCC_00511 5.17e-70 - - - - - - - -
HKAHPFCC_00512 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKAHPFCC_00513 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKAHPFCC_00514 1.99e-165 ybbR - - S - - - YbbR-like protein
HKAHPFCC_00515 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKAHPFCC_00516 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
HKAHPFCC_00517 2.47e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKAHPFCC_00518 2.26e-214 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKAHPFCC_00519 2.36e-216 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HKAHPFCC_00520 6.9e-134 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HKAHPFCC_00521 6.13e-100 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HKAHPFCC_00522 2.63e-115 - - - K - - - Acetyltransferase (GNAT) domain
HKAHPFCC_00523 1.2e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HKAHPFCC_00524 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HKAHPFCC_00525 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKAHPFCC_00526 9.61e-137 - - - - - - - -
HKAHPFCC_00527 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKAHPFCC_00528 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKAHPFCC_00529 6.17e-192 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HKAHPFCC_00530 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HKAHPFCC_00531 0.0 eriC - - P ko:K03281 - ko00000 chloride
HKAHPFCC_00532 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HKAHPFCC_00533 5.59e-54 - - - H - - - RibD C-terminal domain
HKAHPFCC_00534 1.15e-26 - - - S - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKAHPFCC_00535 3.43e-27 - - - L - - - Addiction module antitoxin, RelB DinJ family
HKAHPFCC_00536 6.53e-118 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HKAHPFCC_00537 9.8e-75 - - - S - - - Antibiotic biosynthesis monooxygenase
HKAHPFCC_00538 5.85e-254 flp - - V - - - Beta-lactamase
HKAHPFCC_00539 2.6e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HKAHPFCC_00540 2.81e-158 - - - S ko:K07507 - ko00000,ko02000 MgtC family
HKAHPFCC_00541 4.91e-156 - - - S - - - GyrI-like small molecule binding domain
HKAHPFCC_00543 7.82e-161 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HKAHPFCC_00544 1.58e-66 azlD - - E - - - Branched-chain amino acid transport
HKAHPFCC_00545 5.61e-156 azlC - - E - - - azaleucine resistance protein AzlC
HKAHPFCC_00546 0.0 - - - K - - - Aminotransferase class I and II
HKAHPFCC_00547 0.0 - - - S - - - amidohydrolase
HKAHPFCC_00548 1.86e-212 - - - S - - - reductase
HKAHPFCC_00549 2.55e-120 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
HKAHPFCC_00550 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HKAHPFCC_00551 1.81e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HKAHPFCC_00552 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKAHPFCC_00553 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HKAHPFCC_00554 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKAHPFCC_00555 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKAHPFCC_00556 3.01e-177 jag - - S ko:K06346 - ko00000 R3H domain protein
HKAHPFCC_00557 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKAHPFCC_00558 2.41e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKAHPFCC_00559 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HKAHPFCC_00560 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKAHPFCC_00561 8.49e-265 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKAHPFCC_00562 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HKAHPFCC_00563 2.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKAHPFCC_00564 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKAHPFCC_00565 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKAHPFCC_00566 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HKAHPFCC_00567 1.03e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKAHPFCC_00568 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKAHPFCC_00569 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HKAHPFCC_00570 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HKAHPFCC_00571 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HKAHPFCC_00572 3.37e-272 yttB - - EGP - - - Major Facilitator
HKAHPFCC_00573 1.56e-80 - - - - - - - -
HKAHPFCC_00574 1.36e-212 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
HKAHPFCC_00575 5.2e-132 - - - K - - - DNA-binding helix-turn-helix protein
HKAHPFCC_00577 6.55e-97 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HKAHPFCC_00578 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HKAHPFCC_00580 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HKAHPFCC_00581 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKAHPFCC_00582 0.0 yycH - - S - - - YycH protein
HKAHPFCC_00583 6.38e-196 yycI - - S - - - YycH protein
HKAHPFCC_00584 3.06e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HKAHPFCC_00585 6.24e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HKAHPFCC_00586 5.79e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
HKAHPFCC_00587 1.02e-232 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HKAHPFCC_00588 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKAHPFCC_00590 1.56e-125 - - - S - - - reductase
HKAHPFCC_00591 1.08e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HKAHPFCC_00592 8.4e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HKAHPFCC_00593 3.72e-193 - - - E - - - Glyoxalase-like domain
HKAHPFCC_00594 2.13e-189 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKAHPFCC_00595 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HKAHPFCC_00596 1.06e-202 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKAHPFCC_00597 1.69e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HKAHPFCC_00598 3.16e-278 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HKAHPFCC_00600 7.63e-64 - - - - - - - -
HKAHPFCC_00601 0.0 - - - S - - - Putative peptidoglycan binding domain
HKAHPFCC_00604 1.37e-35 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HKAHPFCC_00605 6.86e-98 - - - O - - - OsmC-like protein
HKAHPFCC_00606 5.24e-232 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKAHPFCC_00607 2.83e-282 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKAHPFCC_00608 8.68e-44 - - - - - - - -
HKAHPFCC_00609 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
HKAHPFCC_00611 1.22e-139 - - - K - - - PFAM GCN5-related N-acetyltransferase
HKAHPFCC_00612 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKAHPFCC_00613 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKAHPFCC_00614 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HKAHPFCC_00615 9.34e-225 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HKAHPFCC_00616 4.84e-277 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HKAHPFCC_00617 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HKAHPFCC_00618 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HKAHPFCC_00619 4.32e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HKAHPFCC_00620 8.58e-94 - - - - - - - -
HKAHPFCC_00621 2.92e-111 - - - T - - - Region found in RelA / SpoT proteins
HKAHPFCC_00622 1.1e-153 dltr - - K - - - response regulator
HKAHPFCC_00623 5.59e-290 sptS - - T - - - Histidine kinase
HKAHPFCC_00624 7.76e-279 - - - P - - - Voltage gated chloride channel
HKAHPFCC_00625 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HKAHPFCC_00626 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HKAHPFCC_00627 1.29e-176 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HKAHPFCC_00628 1.54e-216 - - - C - - - Aldo keto reductase
HKAHPFCC_00629 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HKAHPFCC_00630 6.51e-114 - - - S - - - ECF-type riboflavin transporter, S component
HKAHPFCC_00631 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HKAHPFCC_00632 2.95e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKAHPFCC_00633 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKAHPFCC_00634 2.31e-131 - - - - - - - -
HKAHPFCC_00635 1.14e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKAHPFCC_00637 3.62e-308 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HKAHPFCC_00638 4.72e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
HKAHPFCC_00639 8.71e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HKAHPFCC_00640 5.46e-315 - - - E - - - amino acid
HKAHPFCC_00641 1.64e-18 - - - K - - - Transcriptional regulator, TetR family
HKAHPFCC_00642 4.39e-94 - - - K - - - Transcriptional regulator, TetR family
HKAHPFCC_00643 8.53e-95 - - - - - - - -
HKAHPFCC_00644 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HKAHPFCC_00645 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HKAHPFCC_00646 0.0 - - - M - - - domain protein
HKAHPFCC_00647 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HKAHPFCC_00648 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HKAHPFCC_00649 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HKAHPFCC_00650 3.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HKAHPFCC_00651 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HKAHPFCC_00652 2.07e-236 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HKAHPFCC_00653 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKAHPFCC_00655 6e-132 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HKAHPFCC_00656 3e-274 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HKAHPFCC_00657 2.4e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKAHPFCC_00658 2.98e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HKAHPFCC_00659 4.7e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HKAHPFCC_00660 7.96e-45 - - - S - - - Protein of unknown function (DUF2969)
HKAHPFCC_00661 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HKAHPFCC_00662 7.7e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKAHPFCC_00663 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
HKAHPFCC_00664 8.95e-90 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HKAHPFCC_00665 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKAHPFCC_00666 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKAHPFCC_00667 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKAHPFCC_00668 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKAHPFCC_00669 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKAHPFCC_00670 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKAHPFCC_00671 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HKAHPFCC_00672 9.76e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HKAHPFCC_00673 4.22e-169 yibF - - S - - - overlaps another CDS with the same product name
HKAHPFCC_00674 1.27e-250 yibE - - S - - - overlaps another CDS with the same product name
HKAHPFCC_00675 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKAHPFCC_00676 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKAHPFCC_00677 9.39e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKAHPFCC_00678 6.56e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKAHPFCC_00679 7.63e-217 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKAHPFCC_00680 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKAHPFCC_00681 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HKAHPFCC_00682 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
HKAHPFCC_00683 1.19e-173 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HKAHPFCC_00684 1.07e-301 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
HKAHPFCC_00685 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HKAHPFCC_00686 3.05e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HKAHPFCC_00687 1.25e-304 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HKAHPFCC_00688 3e-251 ampC - - V - - - Beta-lactamase
HKAHPFCC_00689 2.51e-83 - - - - - - - -
HKAHPFCC_00690 2.52e-123 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HKAHPFCC_00691 4.64e-37 - - - Q - - - pyridine nucleotide-disulphide oxidoreductase
HKAHPFCC_00692 6.71e-207 - - - EG - - - EamA-like transporter family
HKAHPFCC_00693 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKAHPFCC_00694 2.04e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HKAHPFCC_00695 4.23e-289 - - - S ko:K07133 - ko00000 cog cog1373
HKAHPFCC_00697 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HKAHPFCC_00698 1.48e-64 - - - V - - - DNA modification
HKAHPFCC_00699 0.0 - - - G - - - Major Facilitator Superfamily
HKAHPFCC_00700 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HKAHPFCC_00701 1.43e-110 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKAHPFCC_00702 3.94e-221 - - - - - - - -
HKAHPFCC_00703 0.0 - - - - - - - -
HKAHPFCC_00705 7.81e-46 - - - S - - - Domain of unknown function (DUF3173)
HKAHPFCC_00706 1.51e-301 - - - L - - - Belongs to the 'phage' integrase family
HKAHPFCC_00707 5.16e-289 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HKAHPFCC_00708 1.03e-206 - - - J - - - Methyltransferase
HKAHPFCC_00709 5.37e-112 ywlG - - S - - - Belongs to the UPF0340 family
HKAHPFCC_00710 1.97e-257 - - - EGP - - - Major Facilitator
HKAHPFCC_00711 1.71e-173 - - - M - - - Lysin motif
HKAHPFCC_00712 9.83e-106 - - - - - - - -
HKAHPFCC_00713 1.52e-125 - - - K - - - PFAM GCN5-related N-acetyltransferase
HKAHPFCC_00714 7.09e-273 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HKAHPFCC_00715 5.26e-19 - - - - - - - -
HKAHPFCC_00716 3.85e-123 - - - S - - - Domain of unknown function (DUF4767)
HKAHPFCC_00717 2.54e-36 - - - - - - - -
HKAHPFCC_00718 9.92e-53 - - - S - - - Cytochrome B5
HKAHPFCC_00719 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
HKAHPFCC_00720 8e-230 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKAHPFCC_00721 4.82e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HKAHPFCC_00722 6.85e-295 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HKAHPFCC_00723 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKAHPFCC_00724 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HKAHPFCC_00725 9.69e-38 - - - - - - - -
HKAHPFCC_00726 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HKAHPFCC_00727 1.56e-130 - - - S - - - Pfam:DUF3816
HKAHPFCC_00728 9.48e-183 - - - G - - - MucBP domain
HKAHPFCC_00729 1.27e-151 - - - - - - - -
HKAHPFCC_00730 2.73e-205 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_00731 1.45e-85 - - - K - - - Transcriptional regulator, GntR family
HKAHPFCC_00732 6.81e-221 - 3.2.1.23, 3.2.1.89 - G ko:K01190,ko:K01224 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 arabinogalactan endo-1,4-beta-galactosidase activity
HKAHPFCC_00733 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HKAHPFCC_00734 8.12e-64 - - - S - - - dextransucrase activity
HKAHPFCC_00735 1.45e-57 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HKAHPFCC_00736 1.08e-209 - - - L ko:K07497 - ko00000 hmm pf00665
HKAHPFCC_00737 2.05e-72 - - - L - - - Helix-turn-helix domain
HKAHPFCC_00738 2.09e-41 - - - L - - - Helix-turn-helix domain
HKAHPFCC_00739 0.0 - - - L - - - Transposase
HKAHPFCC_00740 1.21e-35 - - - L - - - Transposase
HKAHPFCC_00741 9.89e-76 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HKAHPFCC_00742 5.96e-125 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
HKAHPFCC_00743 7.81e-148 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HKAHPFCC_00745 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
HKAHPFCC_00746 7.03e-156 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HKAHPFCC_00747 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKAHPFCC_00748 2.68e-110 - - - - - - - -
HKAHPFCC_00749 5.12e-243 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HKAHPFCC_00750 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HKAHPFCC_00751 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HKAHPFCC_00752 8.36e-231 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKAHPFCC_00753 8.07e-204 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HKAHPFCC_00754 4.7e-186 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Putative cyclase
HKAHPFCC_00755 7.22e-286 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HKAHPFCC_00756 2.22e-168 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKAHPFCC_00757 6.3e-292 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HKAHPFCC_00758 1.73e-215 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HKAHPFCC_00759 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKAHPFCC_00762 8.1e-160 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HKAHPFCC_00763 8.64e-196 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKAHPFCC_00764 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
HKAHPFCC_00765 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HKAHPFCC_00766 3.09e-209 - - - L ko:K07497 - ko00000 hmm pf00665
HKAHPFCC_00767 1.61e-163 - - - L - - - Helix-turn-helix domain
HKAHPFCC_00768 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKAHPFCC_00769 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HKAHPFCC_00770 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HKAHPFCC_00771 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKAHPFCC_00772 8.53e-120 - - - - - - - -
HKAHPFCC_00773 4.1e-51 - - - - - - - -
HKAHPFCC_00774 6.28e-136 - - - K - - - DNA-templated transcription, initiation
HKAHPFCC_00775 7.59e-37 - - - - - - - -
HKAHPFCC_00776 6.85e-115 - - - - - - - -
HKAHPFCC_00777 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HKAHPFCC_00778 2.64e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKAHPFCC_00779 2.77e-219 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKAHPFCC_00780 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKAHPFCC_00781 1.05e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HKAHPFCC_00782 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKAHPFCC_00783 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
HKAHPFCC_00784 4.31e-76 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HKAHPFCC_00785 1.01e-52 yabO - - J - - - S4 domain protein
HKAHPFCC_00786 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKAHPFCC_00787 1.38e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKAHPFCC_00788 8.08e-147 - - - S - - - (CBS) domain
HKAHPFCC_00789 2.06e-188 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HKAHPFCC_00790 9.6e-310 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
HKAHPFCC_00791 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HKAHPFCC_00792 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HKAHPFCC_00793 2.28e-271 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKAHPFCC_00794 2.29e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKAHPFCC_00795 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HKAHPFCC_00796 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKAHPFCC_00797 3.3e-302 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HKAHPFCC_00798 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKAHPFCC_00799 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKAHPFCC_00801 9.88e-239 - - - - - - - -
HKAHPFCC_00802 7.82e-37 - - - - - - - -
HKAHPFCC_00803 7.77e-196 - - - G - - - Belongs to the phosphoglycerate mutase family
HKAHPFCC_00804 1.9e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKAHPFCC_00805 3.82e-133 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HKAHPFCC_00806 5.2e-89 - - - - - - - -
HKAHPFCC_00807 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HKAHPFCC_00808 1.24e-136 - - - L - - - nuclease
HKAHPFCC_00809 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HKAHPFCC_00810 7.33e-271 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKAHPFCC_00811 1.63e-187 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HKAHPFCC_00812 1.77e-203 snf - - KL - - - domain protein
HKAHPFCC_00813 0.0 snf - - KL - - - domain protein
HKAHPFCC_00815 4.51e-192 - - - S - - - Protein of unknown function (DUF3800)
HKAHPFCC_00816 3.07e-05 - - - K - - - sequence-specific DNA binding
HKAHPFCC_00818 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HKAHPFCC_00819 1.49e-225 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HKAHPFCC_00820 9.76e-93 - - - O - - - Preprotein translocase subunit SecB
HKAHPFCC_00821 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKAHPFCC_00822 1.78e-204 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HKAHPFCC_00823 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HKAHPFCC_00825 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKAHPFCC_00826 3.41e-296 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HKAHPFCC_00827 2.9e-158 - - - S - - - SNARE associated Golgi protein
HKAHPFCC_00828 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
HKAHPFCC_00829 1.27e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKAHPFCC_00830 7.82e-80 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKAHPFCC_00831 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKAHPFCC_00832 2.92e-192 - - - S - - - DUF218 domain
HKAHPFCC_00833 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HKAHPFCC_00834 0.0 yhdP - - S - - - Transporter associated domain
HKAHPFCC_00835 1.68e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HKAHPFCC_00836 2.6e-312 - - - U - - - Belongs to the major facilitator superfamily
HKAHPFCC_00837 1.35e-97 - - - S - - - UPF0756 membrane protein
HKAHPFCC_00838 1.42e-82 - - - S - - - Cupin domain
HKAHPFCC_00839 7.72e-114 - - - C - - - Flavodoxin
HKAHPFCC_00840 2.08e-208 rlrB - - K - - - LysR substrate binding domain protein
HKAHPFCC_00841 2.79e-225 yvgN - - C - - - Aldo keto reductase
HKAHPFCC_00842 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HKAHPFCC_00843 9.81e-314 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HKAHPFCC_00846 8.21e-19 - - - LM - - - gp58-like protein
HKAHPFCC_00847 0.0 - - - S - - - Peptidase family M23
HKAHPFCC_00848 1.49e-222 - - - S - - - Phage tail protein
HKAHPFCC_00849 0.0 - - - D - - - domain protein
HKAHPFCC_00850 1.55e-122 - - - S - - - Phage tail assembly chaperone protein, TAC
HKAHPFCC_00851 2.24e-159 - - - - - - - -
HKAHPFCC_00852 5.74e-94 - - - - - - - -
HKAHPFCC_00853 5.18e-128 - - - - - - - -
HKAHPFCC_00854 3.92e-70 - - - - - - - -
HKAHPFCC_00855 1.8e-83 - - - S - - - Phage gp6-like head-tail connector protein
HKAHPFCC_00856 8.1e-261 gpG - - - - - - -
HKAHPFCC_00857 1e-138 - - - S - - - Domain of unknown function (DUF4355)
HKAHPFCC_00859 5.45e-231 - - - S - - - Phage Mu protein F like protein
HKAHPFCC_00860 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HKAHPFCC_00861 0.0 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
HKAHPFCC_00863 1.14e-183 - - - K - - - Belongs to the N(4) N(6)-methyltransferase family
HKAHPFCC_00864 7.15e-95 - - - - - - - -
HKAHPFCC_00865 8.42e-163 - 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 sulfate reduction
HKAHPFCC_00868 2.9e-23 spoIVFA - GT2,GT4 D ko:K05802,ko:K06401,ko:K20444,ko:K22051 - ko00000,ko01000,ko01005,ko02000 peptidase
HKAHPFCC_00869 0.0 - - - M - - - Prophage endopeptidase tail
HKAHPFCC_00870 7.27e-207 - - - S - - - Phage tail protein
HKAHPFCC_00871 0.0 - - - L - - - Phage tail tape measure protein TP901
HKAHPFCC_00872 6.12e-83 - - - S - - - Phage tail assembly chaperone proteins, TAC
HKAHPFCC_00873 4.5e-174 - - - S - - - Phage tail tube protein
HKAHPFCC_00874 3.7e-88 - - - S - - - Protein of unknown function (DUF806)
HKAHPFCC_00875 1.11e-92 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HKAHPFCC_00876 4.51e-77 - - - S - - - Phage head-tail joining protein
HKAHPFCC_00877 4.41e-80 - - - S - - - Phage gp6-like head-tail connector protein
HKAHPFCC_00878 3.68e-276 - - - S - - - Phage capsid family
HKAHPFCC_00879 9.31e-166 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HKAHPFCC_00880 1.85e-283 - - - S - - - Phage portal protein
HKAHPFCC_00881 0.0 - - - S - - - Phage Terminase
HKAHPFCC_00882 1.59e-13 - - - - - - - -
HKAHPFCC_00884 1.1e-108 - - - L - - - Phage terminase, small subunit
HKAHPFCC_00885 1.51e-132 - - - L - - - HNH nucleases
HKAHPFCC_00886 2.71e-14 - - - - - - - -
HKAHPFCC_00887 4.18e-168 - - - F - - - glutamine amidotransferase
HKAHPFCC_00888 1.74e-85 - - - - - - - -
HKAHPFCC_00889 1.15e-147 - - - GM - - - NAD(P)H-binding
HKAHPFCC_00890 6.54e-253 - - - S - - - membrane
HKAHPFCC_00891 6.78e-136 - - - K - - - Transcriptional regulator C-terminal region
HKAHPFCC_00892 5.33e-210 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HKAHPFCC_00893 1.64e-203 - - - K - - - Transcriptional regulator
HKAHPFCC_00894 3.43e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
HKAHPFCC_00895 1.45e-214 ypuA - - S - - - Protein of unknown function (DUF1002)
HKAHPFCC_00896 1.17e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HKAHPFCC_00897 2.28e-223 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HKAHPFCC_00898 1.46e-196 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HKAHPFCC_00899 2.15e-171 - - - S - - - Alpha beta hydrolase
HKAHPFCC_00900 1.48e-05 - - - S - - - Hydrolases of the alpha beta superfamily
HKAHPFCC_00901 2.21e-115 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HKAHPFCC_00902 1.35e-206 lysR - - K - - - Transcriptional regulator
HKAHPFCC_00903 5e-116 - - - C - - - Flavodoxin
HKAHPFCC_00904 1.16e-14 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HKAHPFCC_00905 2e-73 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HKAHPFCC_00906 6.2e-155 - - - M - - - Protein of unknown function (DUF3737)
HKAHPFCC_00907 1.21e-292 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HKAHPFCC_00908 3.3e-208 - - - S ko:K07088 - ko00000 Membrane transport protein
HKAHPFCC_00909 1.76e-161 - - - H - - - RibD C-terminal domain
HKAHPFCC_00911 2.9e-228 - - - L ko:K07455 - ko00000,ko03400 RecT family
HKAHPFCC_00915 3.7e-25 - - - - - - - -
HKAHPFCC_00916 2.73e-181 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HKAHPFCC_00917 2.72e-42 - - - K - - - Helix-turn-helix XRE-family like proteins
HKAHPFCC_00918 2.37e-95 - - - K - - - Cro/C1-type HTH DNA-binding domain
HKAHPFCC_00919 2.76e-108 - - - E - - - IrrE N-terminal-like domain
HKAHPFCC_00920 1.48e-66 - - - M - - - Host cell surface-exposed lipoprotein
HKAHPFCC_00921 2.86e-68 - - - - - - - -
HKAHPFCC_00922 1.66e-269 - - - L - - - Belongs to the 'phage' integrase family
HKAHPFCC_00923 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKAHPFCC_00924 0.0 - - - E ko:K03294 - ko00000 amino acid
HKAHPFCC_00925 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HKAHPFCC_00926 1.86e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKAHPFCC_00927 3.74e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HKAHPFCC_00928 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HKAHPFCC_00929 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKAHPFCC_00930 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKAHPFCC_00931 4.22e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKAHPFCC_00932 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HKAHPFCC_00933 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKAHPFCC_00934 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKAHPFCC_00935 1.41e-242 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKAHPFCC_00936 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKAHPFCC_00937 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HKAHPFCC_00938 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
HKAHPFCC_00939 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HKAHPFCC_00940 6.95e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HKAHPFCC_00941 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HKAHPFCC_00942 1.59e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKAHPFCC_00943 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HKAHPFCC_00944 4.45e-170 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HKAHPFCC_00945 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKAHPFCC_00946 1.81e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKAHPFCC_00947 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKAHPFCC_00948 1.97e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKAHPFCC_00949 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKAHPFCC_00950 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HKAHPFCC_00951 9e-72 - - - - - - - -
HKAHPFCC_00952 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HKAHPFCC_00953 6.71e-102 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HKAHPFCC_00954 1.69e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HKAHPFCC_00955 3.59e-207 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKAHPFCC_00956 9.86e-59 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKAHPFCC_00957 5.04e-283 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKAHPFCC_00958 2.71e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKAHPFCC_00959 9.11e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKAHPFCC_00960 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HKAHPFCC_00961 6.38e-159 - - - J - - - 2'-5' RNA ligase superfamily
HKAHPFCC_00962 2.83e-261 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HKAHPFCC_00963 1.63e-171 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKAHPFCC_00964 5.07e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HKAHPFCC_00965 8.76e-73 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HKAHPFCC_00966 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HKAHPFCC_00967 1.99e-146 - - - K - - - Transcriptional regulator
HKAHPFCC_00970 3.61e-117 - - - S - - - Protein conserved in bacteria
HKAHPFCC_00971 2.07e-239 - - - - - - - -
HKAHPFCC_00972 8.42e-204 - - - - - - - -
HKAHPFCC_00973 7.62e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
HKAHPFCC_00974 6.94e-132 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKAHPFCC_00975 1.51e-200 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HKAHPFCC_00976 1.28e-18 - - - - - - - -
HKAHPFCC_00977 1.31e-286 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKAHPFCC_00978 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKAHPFCC_00979 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HKAHPFCC_00980 1.06e-228 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKAHPFCC_00981 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
HKAHPFCC_00982 2.67e-88 yqhL - - P - - - Rhodanese-like protein
HKAHPFCC_00983 2.51e-235 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HKAHPFCC_00984 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HKAHPFCC_00985 1.44e-148 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HKAHPFCC_00986 9.73e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKAHPFCC_00987 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HKAHPFCC_00988 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HKAHPFCC_00989 0.0 - - - S - - - membrane
HKAHPFCC_00990 4.64e-92 yneR - - S - - - Belongs to the HesB IscA family
HKAHPFCC_00991 6.08e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKAHPFCC_00992 2.06e-152 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HKAHPFCC_00993 6.17e-151 - - - M - - - PFAM NLP P60 protein
HKAHPFCC_00994 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKAHPFCC_00995 3.66e-252 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKAHPFCC_00996 4.77e-77 yodB - - K - - - Transcriptional regulator, HxlR family
HKAHPFCC_00997 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKAHPFCC_00998 6.64e-187 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKAHPFCC_00999 1.07e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HKAHPFCC_01000 9.55e-216 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKAHPFCC_01001 5.74e-94 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKAHPFCC_01002 1.84e-298 - - - V - - - MatE
HKAHPFCC_01003 0.0 potE - - E - - - Amino Acid
HKAHPFCC_01004 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKAHPFCC_01005 1.38e-155 csrR - - K - - - response regulator
HKAHPFCC_01006 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HKAHPFCC_01007 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HKAHPFCC_01008 1.75e-276 ylbM - - S - - - Belongs to the UPF0348 family
HKAHPFCC_01009 9.84e-183 yqeM - - Q - - - Methyltransferase
HKAHPFCC_01010 2.3e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKAHPFCC_01011 1.07e-147 yqeK - - H - - - Hydrolase, HD family
HKAHPFCC_01012 4.36e-161 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKAHPFCC_01013 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HKAHPFCC_01014 1.9e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HKAHPFCC_01015 1.91e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HKAHPFCC_01016 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKAHPFCC_01017 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HKAHPFCC_01018 2.15e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKAHPFCC_01019 2.57e-223 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HKAHPFCC_01020 2.42e-300 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HKAHPFCC_01021 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKAHPFCC_01022 5.5e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKAHPFCC_01023 8.18e-206 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKAHPFCC_01024 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKAHPFCC_01025 5.87e-155 - - - S - - - Protein of unknown function (DUF1275)
HKAHPFCC_01026 4.56e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HKAHPFCC_01027 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HKAHPFCC_01028 3.43e-154 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKAHPFCC_01029 2.95e-75 ytpP - - CO - - - Thioredoxin
HKAHPFCC_01030 2.27e-75 - - - S - - - Small secreted protein
HKAHPFCC_01031 1.53e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HKAHPFCC_01032 5.08e-237 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HKAHPFCC_01033 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKAHPFCC_01034 0.0 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKAHPFCC_01035 1.01e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_01036 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HKAHPFCC_01037 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HKAHPFCC_01038 2.34e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HKAHPFCC_01039 6.44e-239 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKAHPFCC_01040 6.2e-305 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKAHPFCC_01041 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HKAHPFCC_01042 7.55e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HKAHPFCC_01043 4.86e-233 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKAHPFCC_01044 6.39e-235 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HKAHPFCC_01045 1.55e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKAHPFCC_01046 1.8e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HKAHPFCC_01047 2.66e-219 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKAHPFCC_01048 3.71e-190 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HKAHPFCC_01049 6.69e-238 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HKAHPFCC_01050 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HKAHPFCC_01051 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKAHPFCC_01052 2.54e-266 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKAHPFCC_01053 2.51e-280 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKAHPFCC_01054 9.45e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
HKAHPFCC_01055 2.97e-130 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
HKAHPFCC_01056 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HKAHPFCC_01057 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKAHPFCC_01058 2.54e-243 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HKAHPFCC_01059 4.94e-109 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HKAHPFCC_01060 1.27e-290 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
HKAHPFCC_01061 4.66e-26 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HKAHPFCC_01062 1.53e-106 - - - L ko:K07484 - ko00000 Transposase IS66 family
HKAHPFCC_01063 0.0 - - - S - - - SEC-C Motif Domain Protein
HKAHPFCC_01064 6.11e-68 - - - - - - - -
HKAHPFCC_01065 2.03e-182 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKAHPFCC_01066 3e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HKAHPFCC_01067 8.1e-153 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKAHPFCC_01068 6.12e-296 - - - P - - - Chloride transporter, ClC family
HKAHPFCC_01069 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HKAHPFCC_01070 5.8e-149 - - - I - - - Acid phosphatase homologues
HKAHPFCC_01071 5.42e-276 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HKAHPFCC_01072 6.61e-194 - - - K - - - Helix-turn-helix XRE-family like proteins
HKAHPFCC_01073 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKAHPFCC_01074 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
HKAHPFCC_01075 2.32e-179 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKAHPFCC_01076 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HKAHPFCC_01077 2.28e-137 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HKAHPFCC_01078 3.74e-204 yvgN - - S - - - Aldo keto reductase
HKAHPFCC_01079 1.3e-265 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
HKAHPFCC_01080 1.95e-109 uspA - - T - - - universal stress protein
HKAHPFCC_01081 3.61e-61 - - - - - - - -
HKAHPFCC_01082 4.83e-312 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HKAHPFCC_01083 3.65e-114 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HKAHPFCC_01084 1.14e-27 - - - - - - - -
HKAHPFCC_01085 4.92e-99 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
HKAHPFCC_01086 4.16e-180 - - - S - - - Membrane
HKAHPFCC_01087 1.24e-182 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HKAHPFCC_01088 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HKAHPFCC_01089 6.74e-209 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKAHPFCC_01090 2.24e-123 - - - - - - - -
HKAHPFCC_01091 1.37e-90 - - - K - - - Transcriptional regulator, HxlR family
HKAHPFCC_01092 2.91e-230 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HKAHPFCC_01093 1.31e-28 epsB - - M - - - biosynthesis protein
HKAHPFCC_01094 1.55e-224 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKAHPFCC_01095 8.85e-208 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKAHPFCC_01096 0.0 - - - S - - - Protein of unknown function (DUF2971)
HKAHPFCC_01097 0.0 - - - S - - - KAP family P-loop domain
HKAHPFCC_01098 0.0 - - - S ko:K07459 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
HKAHPFCC_01099 1.93e-266 - - - L - - - DNA helicase
HKAHPFCC_01100 2.9e-295 - - - L - - - Integrase core domain
HKAHPFCC_01101 7.45e-181 - - - L - - - Bacterial dnaA protein
HKAHPFCC_01102 1.01e-203 - - - - - - - -
HKAHPFCC_01103 9.94e-148 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HKAHPFCC_01104 8.4e-259 xerS - - L - - - Belongs to the 'phage' integrase family
HKAHPFCC_01106 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKAHPFCC_01107 2.35e-101 - - - K - - - Transcriptional regulator, MarR family
HKAHPFCC_01108 4.83e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKAHPFCC_01109 2.51e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKAHPFCC_01110 2.23e-209 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HKAHPFCC_01111 7.69e-170 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HKAHPFCC_01112 1.27e-288 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKAHPFCC_01113 1.3e-99 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKAHPFCC_01114 1.38e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKAHPFCC_01115 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HKAHPFCC_01116 7.2e-185 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKAHPFCC_01117 5.87e-181 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HKAHPFCC_01118 1.04e-172 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HKAHPFCC_01127 1.57e-73 - - - - - - - -
HKAHPFCC_01128 5.47e-151 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
HKAHPFCC_01129 5.51e-213 - - - I - - - alpha/beta hydrolase fold
HKAHPFCC_01130 6.14e-215 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HKAHPFCC_01131 4.68e-197 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKAHPFCC_01132 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKAHPFCC_01133 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKAHPFCC_01134 1.84e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HKAHPFCC_01135 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
HKAHPFCC_01136 5.7e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKAHPFCC_01137 1.84e-155 - - - G - - - Belongs to the phosphoglycerate mutase family
HKAHPFCC_01138 1.59e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HKAHPFCC_01139 3.01e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKAHPFCC_01140 4.29e-162 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HKAHPFCC_01141 8.23e-216 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKAHPFCC_01142 2.02e-306 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKAHPFCC_01143 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HKAHPFCC_01144 6.72e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKAHPFCC_01145 2.59e-89 - - - S - - - Belongs to the HesB IscA family
HKAHPFCC_01146 4.18e-43 - - - - - - - -
HKAHPFCC_01148 9.65e-120 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HKAHPFCC_01149 1.15e-82 asp1 - - S - - - Asp23 family, cell envelope-related function
HKAHPFCC_01150 3.09e-35 - - - - - - - -
HKAHPFCC_01151 1.38e-125 - - - - - - - -
HKAHPFCC_01152 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HKAHPFCC_01153 2.49e-235 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
HKAHPFCC_01154 8.68e-257 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HKAHPFCC_01155 7.28e-305 int - - L ko:K06400 - ko00000 COG1961 Site-specific recombinases, DNA invertase Pin homologs
HKAHPFCC_01156 4.28e-192 - - - - - - - -
HKAHPFCC_01158 3.75e-98 - - - - - - - -
HKAHPFCC_01159 2.86e-93 - - - S - - - IrrE N-terminal-like domain
HKAHPFCC_01160 3.02e-62 - - - K - - - Helix-turn-helix domain
HKAHPFCC_01161 3.73e-44 - - - K - - - Helix-turn-helix XRE-family like proteins
HKAHPFCC_01162 1.1e-180 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HKAHPFCC_01165 1.98e-44 - - - - - - - -
HKAHPFCC_01166 1.35e-05 - - - K - - - XRE family transcriptional regulator
HKAHPFCC_01170 1.03e-211 - - - L ko:K07455 - ko00000,ko03400 RecT family
HKAHPFCC_01171 8.56e-236 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HKAHPFCC_01172 2.11e-250 - - - S - - - enterobacterial common antigen metabolic process
HKAHPFCC_01173 3.11e-248 - - - M - - - transferase activity, transferring glycosyl groups
HKAHPFCC_01174 1.23e-255 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
HKAHPFCC_01175 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HKAHPFCC_01176 1.82e-137 - - - M - - - biosynthesis protein
HKAHPFCC_01177 2.22e-276 cps3F - - - - - - -
HKAHPFCC_01178 3.84e-282 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HKAHPFCC_01179 3.06e-157 - - - M - - - Bacterial sugar transferase
HKAHPFCC_01180 5.87e-227 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HKAHPFCC_01181 2.95e-193 cps1D - - M - - - Domain of unknown function (DUF4422)
HKAHPFCC_01182 6.84e-183 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HKAHPFCC_01183 6.21e-43 - - - - - - - -
HKAHPFCC_01184 8.85e-47 - - - S - - - Protein of unknown function (DUF2922)
HKAHPFCC_01185 9.09e-204 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HKAHPFCC_01189 6.08e-305 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HKAHPFCC_01190 1.28e-75 - - - - - - - -
HKAHPFCC_01192 2.91e-118 - - - - - - - -
HKAHPFCC_01193 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HKAHPFCC_01194 2.2e-65 - - - S - - - Cupredoxin-like domain
HKAHPFCC_01195 1.53e-71 - - - S - - - Cupredoxin-like domain
HKAHPFCC_01196 1.04e-135 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HKAHPFCC_01197 1.92e-209 - - - EG - - - EamA-like transporter family
HKAHPFCC_01198 1.37e-221 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HKAHPFCC_01199 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKAHPFCC_01200 2.24e-200 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
HKAHPFCC_01201 5.86e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HKAHPFCC_01202 3.02e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HKAHPFCC_01203 1.74e-252 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKAHPFCC_01204 1.87e-172 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKAHPFCC_01205 1.62e-293 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKAHPFCC_01206 2.29e-180 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKAHPFCC_01207 3.05e-189 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HKAHPFCC_01208 1.37e-292 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKAHPFCC_01209 1.92e-238 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKAHPFCC_01210 5.26e-253 - - - S - - - Uncharacterised protein family (UPF0236)
HKAHPFCC_01211 0.0 - - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HKAHPFCC_01212 2.32e-234 - 4.1.1.22 - H ko:K01590 ko00340,ko01100,ko01110,map00340,map01100,map01110 ko00000,ko00001,ko01000 Histidine carboxylase PI chain
HKAHPFCC_01213 5.94e-128 - - - S - - - Family of unknown function (DUF5449)
HKAHPFCC_01214 9.6e-317 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HKAHPFCC_01215 4.33e-315 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HKAHPFCC_01216 5.83e-308 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HKAHPFCC_01217 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKAHPFCC_01218 8.21e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HKAHPFCC_01219 9.37e-227 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HKAHPFCC_01220 3.78e-169 yceF - - P ko:K05794 - ko00000 membrane
HKAHPFCC_01221 6.46e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HKAHPFCC_01222 6.78e-306 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HKAHPFCC_01223 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HKAHPFCC_01224 6.27e-125 - - - P - - - Cadmium resistance transporter
HKAHPFCC_01225 3.96e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_01226 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HKAHPFCC_01227 7.76e-234 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HKAHPFCC_01228 3.5e-186 - - - M - - - PFAM NLP P60 protein
HKAHPFCC_01230 3.01e-19 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HKAHPFCC_01231 1.15e-139 - - - S - - - Protein of unknown function (DUF3278)
HKAHPFCC_01234 0.0 - - - S - - - ABC transporter, ATP-binding protein
HKAHPFCC_01235 1.57e-190 - - - S - - - Putative ABC-transporter type IV
HKAHPFCC_01236 1.79e-138 - - - NU - - - mannosyl-glycoprotein
HKAHPFCC_01237 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HKAHPFCC_01238 2.81e-297 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HKAHPFCC_01239 5.51e-264 yngD - - S ko:K07097 - ko00000 DHHA1 domain
HKAHPFCC_01240 2.48e-66 - - - - - - - -
HKAHPFCC_01241 4.75e-184 - - - S - - - PD-(D/E)XK nuclease family transposase
HKAHPFCC_01243 8.14e-73 - - - - - - - -
HKAHPFCC_01244 2.8e-159 yrkL - - S - - - Flavodoxin-like fold
HKAHPFCC_01246 1.92e-86 yeaO - - S - - - Protein of unknown function, DUF488
HKAHPFCC_01247 8.15e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HKAHPFCC_01248 3.49e-269 - - - S - - - associated with various cellular activities
HKAHPFCC_01249 2.59e-314 - - - S - - - Putative metallopeptidase domain
HKAHPFCC_01250 1.48e-64 - - - - - - - -
HKAHPFCC_01251 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HKAHPFCC_01252 1.03e-146 - - - K - - - Helix-turn-helix XRE-family like proteins
HKAHPFCC_01253 8.53e-120 ymdB - - S - - - Macro domain protein
HKAHPFCC_01254 7.66e-255 - - - EGP - - - Major Facilitator
HKAHPFCC_01255 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKAHPFCC_01256 4.75e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HKAHPFCC_01257 1.78e-204 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HKAHPFCC_01258 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HKAHPFCC_01259 5.22e-176 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_01260 7.79e-236 - - - T - - - Histidine kinase-like ATPases
HKAHPFCC_01261 6.91e-164 XK27_10500 - - K - - - response regulator
HKAHPFCC_01262 2.25e-205 yvgN - - S - - - Aldo keto reductase
HKAHPFCC_01263 5.87e-177 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HKAHPFCC_01264 8.19e-108 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKAHPFCC_01265 2.72e-262 - - - - - - - -
HKAHPFCC_01266 4.33e-69 - - - - - - - -
HKAHPFCC_01267 1.21e-48 - - - - - - - -
HKAHPFCC_01268 1.65e-122 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HKAHPFCC_01269 4.87e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HKAHPFCC_01270 7.24e-239 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
HKAHPFCC_01271 1.08e-289 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKAHPFCC_01272 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HKAHPFCC_01273 5.06e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HKAHPFCC_01274 1.31e-140 - - - L - - - Transposase and inactivated derivatives, IS30 family
HKAHPFCC_01275 8.19e-107 - - - L ko:K07482 - ko00000 transposase and inactivated derivatives, IS30 family
HKAHPFCC_01276 9.09e-142 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
HKAHPFCC_01277 3.7e-297 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKAHPFCC_01278 1.39e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HKAHPFCC_01279 2.32e-104 usp5 - - T - - - universal stress protein
HKAHPFCC_01280 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HKAHPFCC_01281 3.16e-55 - - - - - - - -
HKAHPFCC_01282 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKAHPFCC_01283 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKAHPFCC_01284 1.59e-247 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HKAHPFCC_01285 1.82e-97 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
HKAHPFCC_01286 1.98e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HKAHPFCC_01287 6.04e-309 yhdP - - S - - - Transporter associated domain
HKAHPFCC_01288 1.51e-202 - - - V - - - (ABC) transporter
HKAHPFCC_01289 2.93e-119 - - - GM - - - epimerase
HKAHPFCC_01290 1.51e-117 - - - K - - - Domain of unknown function (DUF1836)
HKAHPFCC_01291 5.75e-103 yybA - - K - - - Transcriptional regulator
HKAHPFCC_01292 7.74e-173 XK27_07210 - - S - - - B3 4 domain
HKAHPFCC_01293 2.08e-245 XK27_12525 - - S - - - AI-2E family transporter
HKAHPFCC_01294 5.33e-208 - - - G - - - Xylose isomerase domain protein TIM barrel
HKAHPFCC_01295 5.87e-213 - - - - - - - -
HKAHPFCC_01296 4.17e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HKAHPFCC_01297 3.27e-192 eutJ - - E ko:K04024 - ko00000 Hsp70 protein
HKAHPFCC_01298 1.69e-258 - - - K - - - helix_turn_helix, arabinose operon control protein
HKAHPFCC_01299 2.72e-56 - - - CQ - - - BMC
HKAHPFCC_01300 3.41e-170 pduB - - E - - - BMC
HKAHPFCC_01301 0.0 pduC 4.2.1.28 - Q ko:K01699 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase large subunit
HKAHPFCC_01302 1.33e-166 pduD 4.2.1.28 - Q ko:K13919 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase medium subunit
HKAHPFCC_01303 5.05e-112 pduE 4.2.1.28 - Q ko:K13920 ko00640,map00640 ko00000,ko00001,ko01000 Dehydratase small subunit
HKAHPFCC_01304 0.0 pduG - - D - - - Diol dehydratase reactivase ATPase-like domain
HKAHPFCC_01305 1.44e-79 pduH - - S - - - Dehydratase medium subunit
HKAHPFCC_01306 1.02e-115 - - - CQ - - - BMC
HKAHPFCC_01307 4.11e-57 pduA_2 - - CQ ko:K04027 - ko00000 BMC
HKAHPFCC_01308 1.77e-151 pduL 2.3.1.222 - Q ko:K13923 ko00640,map00640 ko00000,ko00001,ko01000 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HKAHPFCC_01309 2.75e-116 - - - S - - - Putative propanediol utilisation
HKAHPFCC_01310 1.96e-55 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
HKAHPFCC_01311 1.26e-137 - - - S - - - Cobalamin adenosyltransferase
HKAHPFCC_01312 1.01e-104 pduO - - S - - - Haem-degrading
HKAHPFCC_01313 0.0 pduP 1.2.1.87 - C ko:K13922 ko00640,map00640 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HKAHPFCC_01314 6.52e-270 pduQ - - C ko:K13921 ko00640,map00640 ko00000,ko00001 Iron-containing alcohol dehydrogenase
HKAHPFCC_01315 1.3e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKAHPFCC_01316 3.32e-74 - - - E ko:K04031 - ko00000 BMC
HKAHPFCC_01317 1.7e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
HKAHPFCC_01318 4.9e-158 pgm1 - - G - - - phosphoglycerate mutase
HKAHPFCC_01319 5.79e-120 - - - P - - - Cadmium resistance transporter
HKAHPFCC_01320 2.69e-95 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
HKAHPFCC_01321 6.23e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HKAHPFCC_01322 7.23e-202 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HKAHPFCC_01323 1.37e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
HKAHPFCC_01324 4.28e-225 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKAHPFCC_01325 1.52e-198 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKAHPFCC_01326 9.06e-151 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HKAHPFCC_01327 2.51e-150 yjbH - - Q - - - Thioredoxin
HKAHPFCC_01328 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKAHPFCC_01329 2.15e-267 coiA - - S ko:K06198 - ko00000 Competence protein
HKAHPFCC_01330 5.67e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKAHPFCC_01331 4.08e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKAHPFCC_01332 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HKAHPFCC_01333 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKAHPFCC_01334 7.37e-300 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HKAHPFCC_01335 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
HKAHPFCC_01336 5.17e-252 yueF - - S - - - AI-2E family transporter
HKAHPFCC_01337 1.11e-190 - - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 dextransucrase activity
HKAHPFCC_01338 3.7e-11 - - - K - - - Helix-turn-helix XRE-family like proteins
HKAHPFCC_01339 1.54e-05 - - - K - - - Helix-turn-helix XRE-family like proteins
HKAHPFCC_01340 6.4e-26 - - - S - - - Phage derived protein Gp49-like (DUF891)
HKAHPFCC_01341 3.01e-63 int2 - - L - - - Belongs to the 'phage' integrase family
HKAHPFCC_01343 1.94e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
HKAHPFCC_01344 3.73e-203 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HKAHPFCC_01345 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
HKAHPFCC_01346 5.02e-29 - - - - - - - -
HKAHPFCC_01347 5.57e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKAHPFCC_01348 3.57e-150 - - - S - - - Protein of unknown function (DUF421)
HKAHPFCC_01349 2.7e-39 - - - S - - - Protein of unknown function (DUF3290)
HKAHPFCC_01350 5.07e-39 - - - S - - - Protein of unknown function (DUF3290)
HKAHPFCC_01351 7.11e-57 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
HKAHPFCC_01352 4.49e-102 - - - - - - - -
HKAHPFCC_01355 2.17e-10 - - - - - - - -
HKAHPFCC_01364 2.3e-78 - - - - - - - -
HKAHPFCC_01365 1.65e-205 - - - L - - - Psort location Cytoplasmic, score
HKAHPFCC_01366 9.84e-132 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HKAHPFCC_01367 3.96e-88 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HKAHPFCC_01368 3.2e-68 - - - - - - - -
HKAHPFCC_01369 4.14e-230 - - - M - - - Glycosyltransferase like family 2
HKAHPFCC_01370 6.69e-304 - - - L - - - Integrase core domain
HKAHPFCC_01371 1.23e-171 - - - O - - - Bacterial dnaA protein
HKAHPFCC_01373 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKAHPFCC_01374 3.1e-289 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HKAHPFCC_01375 2.51e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKAHPFCC_01376 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKAHPFCC_01379 1.38e-05 - - - - - - - -
HKAHPFCC_01381 1.6e-94 - - - - - - - -
HKAHPFCC_01383 3.92e-87 - - - - - - - -
HKAHPFCC_01384 1.21e-99 - - - S - - - Flavodoxin
HKAHPFCC_01385 3.25e-84 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
HKAHPFCC_01386 1.65e-47 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
HKAHPFCC_01387 5.25e-279 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
HKAHPFCC_01388 3.34e-213 - - - H - - - geranyltranstransferase activity
HKAHPFCC_01389 2.23e-149 - - - - - - - -
HKAHPFCC_01390 6.1e-247 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HKAHPFCC_01391 6.74e-80 - - - S - - - COG5546 Small integral membrane protein
HKAHPFCC_01392 4.85e-57 - - - - - - - -
HKAHPFCC_01394 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKAHPFCC_01395 3.49e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKAHPFCC_01396 1.95e-90 ywiB - - S - - - Domain of unknown function (DUF1934)
HKAHPFCC_01397 7.69e-88 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HKAHPFCC_01399 6.84e-254 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HKAHPFCC_01400 3.61e-209 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HKAHPFCC_01401 2.64e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKAHPFCC_01402 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HKAHPFCC_01403 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
HKAHPFCC_01404 1.6e-77 - - - - - - - -
HKAHPFCC_01405 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HKAHPFCC_01406 1.61e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKAHPFCC_01407 5.99e-74 ftsL - - D - - - Cell division protein FtsL
HKAHPFCC_01408 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HKAHPFCC_01409 3.83e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKAHPFCC_01410 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKAHPFCC_01411 2.16e-262 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKAHPFCC_01412 7.77e-198 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKAHPFCC_01413 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKAHPFCC_01414 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKAHPFCC_01415 1.57e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKAHPFCC_01416 1.11e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HKAHPFCC_01417 1.84e-190 ylmH - - S - - - S4 domain protein
HKAHPFCC_01418 6.11e-108 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HKAHPFCC_01419 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKAHPFCC_01420 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HKAHPFCC_01421 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HKAHPFCC_01422 1.54e-33 - - - - - - - -
HKAHPFCC_01423 3.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKAHPFCC_01424 1.63e-280 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HKAHPFCC_01425 5.58e-76 XK27_04120 - - S - - - Putative amino acid metabolism
HKAHPFCC_01426 2.15e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKAHPFCC_01427 4.89e-160 pgm6 - - G - - - phosphoglycerate mutase
HKAHPFCC_01428 1.1e-156 - - - S - - - repeat protein
HKAHPFCC_01429 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKAHPFCC_01430 3.64e-224 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKAHPFCC_01431 6.48e-243 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKAHPFCC_01432 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HKAHPFCC_01433 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKAHPFCC_01434 1.2e-114 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKAHPFCC_01435 4.19e-286 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKAHPFCC_01436 5.62e-224 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKAHPFCC_01437 1.62e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKAHPFCC_01438 3.19e-283 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKAHPFCC_01439 1.56e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKAHPFCC_01440 6.43e-05 cdaR_3 - - QT ko:K02647 - ko00000,ko03000 PucR C-terminal helix-turn-helix domain
HKAHPFCC_01441 6.84e-35 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
HKAHPFCC_01442 2.31e-281 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
HKAHPFCC_01443 1.73e-270 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HKAHPFCC_01444 5.28e-76 - - - - - - - -
HKAHPFCC_01446 5.28e-254 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HKAHPFCC_01447 4.37e-39 - - - - - - - -
HKAHPFCC_01448 2.71e-235 - - - I - - - Diacylglycerol kinase catalytic
HKAHPFCC_01449 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
HKAHPFCC_01450 2.79e-107 - - - - - - - -
HKAHPFCC_01451 8.3e-134 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKAHPFCC_01452 2.44e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HKAHPFCC_01453 2.31e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HKAHPFCC_01454 1.34e-314 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKAHPFCC_01455 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HKAHPFCC_01456 2.87e-63 yktA - - S - - - Belongs to the UPF0223 family
HKAHPFCC_01457 2.12e-178 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HKAHPFCC_01458 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HKAHPFCC_01459 2.75e-286 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HKAHPFCC_01460 3.83e-61 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HKAHPFCC_01461 2.37e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HKAHPFCC_01462 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKAHPFCC_01463 6.94e-208 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HKAHPFCC_01464 8.7e-141 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HKAHPFCC_01465 2.47e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HKAHPFCC_01466 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HKAHPFCC_01467 5.84e-203 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HKAHPFCC_01468 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HKAHPFCC_01469 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKAHPFCC_01470 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKAHPFCC_01471 1.3e-210 - - - S - - - Tetratricopeptide repeat
HKAHPFCC_01472 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKAHPFCC_01473 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKAHPFCC_01474 5.06e-298 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKAHPFCC_01475 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HKAHPFCC_01476 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
HKAHPFCC_01477 2.44e-20 - - - - - - - -
HKAHPFCC_01478 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKAHPFCC_01479 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKAHPFCC_01480 2.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKAHPFCC_01481 1.05e-201 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HKAHPFCC_01482 5.25e-106 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HKAHPFCC_01486 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
HKAHPFCC_01489 3.72e-111 - - - L - - - HNH nucleases
HKAHPFCC_01491 1.34e-103 terS - - L - - - Phage terminase, small subunit
HKAHPFCC_01492 0.0 terL - - S - - - overlaps another CDS with the same product name
HKAHPFCC_01494 9.18e-265 - - - S - - - Phage portal protein
HKAHPFCC_01495 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HKAHPFCC_01496 3.04e-100 - - - S - - - Transcriptional regulator, RinA family
HKAHPFCC_01497 6.69e-61 - - - S - - - Phage gp6-like head-tail connector protein
HKAHPFCC_01499 3.18e-167 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKAHPFCC_01500 1.49e-272 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HKAHPFCC_01501 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKAHPFCC_01502 2.7e-47 ynzC - - S - - - UPF0291 protein
HKAHPFCC_01503 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HKAHPFCC_01504 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HKAHPFCC_01505 2.92e-182 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HKAHPFCC_01506 6.79e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HKAHPFCC_01507 8.74e-235 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKAHPFCC_01508 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HKAHPFCC_01509 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKAHPFCC_01510 2.21e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HKAHPFCC_01511 7.32e-124 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKAHPFCC_01512 3.97e-198 - - - EG - - - EamA-like transporter family
HKAHPFCC_01513 1.15e-152 - - - L - - - Integrase
HKAHPFCC_01514 8.81e-205 rssA - - S - - - Phospholipase, patatin family
HKAHPFCC_01515 1.48e-242 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HKAHPFCC_01517 1.5e-85 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HKAHPFCC_01518 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HKAHPFCC_01519 8.5e-266 - - - M - - - Rib/alpha-like repeat
HKAHPFCC_01520 4.45e-47 - - - - - - - -
HKAHPFCC_01521 5.41e-73 - - - S - - - Mazg nucleotide pyrophosphohydrolase
HKAHPFCC_01522 1.31e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HKAHPFCC_01542 4.13e-110 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
HKAHPFCC_01543 7.45e-150 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HKAHPFCC_01544 2.45e-26 - - - - - - - -
HKAHPFCC_01545 1.44e-195 - - - L ko:K15342 - ko00000,ko02048,ko03400 reverse transcriptase
HKAHPFCC_01547 6.49e-268 - - - - - - - -
HKAHPFCC_01548 3.08e-267 cobD 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 Aminotransferase class I and II
HKAHPFCC_01549 0.0 cbiA 6.3.5.11, 6.3.5.9 - F ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HKAHPFCC_01550 3.27e-229 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HKAHPFCC_01551 6.88e-160 cbiC 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-8X methylmutase
HKAHPFCC_01552 6.31e-273 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HKAHPFCC_01553 5.13e-144 cbiE 2.1.1.289 - H ko:K03399 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HKAHPFCC_01554 1.28e-127 cbiT 2.1.1.196 - H ko:K02191 ko00860,map00860 ko00000,ko00001,ko01000 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HKAHPFCC_01555 3.02e-176 cbiF 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HKAHPFCC_01556 1.55e-250 cbiG 3.7.1.12 - H ko:K02189 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalamin synthesis G C-terminus
HKAHPFCC_01557 5.23e-171 cbiH 2.1.1.131 - H ko:K05934 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HKAHPFCC_01558 9.74e-177 cobK 1.3.1.106, 1.3.1.54 - H ko:K05895 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-6x reductase CbiJ/CobK
HKAHPFCC_01559 0.0 cobA 2.1.1.107, 4.2.1.75 - H ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HKAHPFCC_01560 1.51e-188 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalt chelatase (CbiK)
HKAHPFCC_01561 2.2e-161 cbiL 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HKAHPFCC_01562 4.44e-171 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HKAHPFCC_01563 2.56e-70 cbiN - - P ko:K02009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HKAHPFCC_01564 1.43e-151 cbiQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HKAHPFCC_01565 1.24e-191 cbiO - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 part of an ABC transporter complex. Responsible for energy coupling to the transport system
HKAHPFCC_01566 0.0 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HKAHPFCC_01567 9.88e-105 cysG 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Putative NAD(P)-binding
HKAHPFCC_01568 3.46e-303 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HKAHPFCC_01569 1.73e-217 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HKAHPFCC_01570 1.39e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Delta-aminolevulinic acid dehydratase
HKAHPFCC_01571 0.0 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HKAHPFCC_01572 1.47e-132 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobinamide kinase / cobinamide phosphate guanyltransferase
HKAHPFCC_01573 1.05e-176 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HKAHPFCC_01574 3.23e-145 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HKAHPFCC_01575 2.5e-171 - - - H - - - Uroporphyrinogen-III synthase
HKAHPFCC_01576 1.6e-247 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HKAHPFCC_01577 3.57e-81 - - - S - - - Domain of unknown function (DUF4430)
HKAHPFCC_01578 4.13e-116 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
HKAHPFCC_01579 4.05e-242 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKAHPFCC_01580 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_01581 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HKAHPFCC_01582 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKAHPFCC_01583 6.99e-115 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKAHPFCC_01584 2.22e-173 gntR - - K - - - UbiC transcription regulator-associated domain protein
HKAHPFCC_01585 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HKAHPFCC_01586 3.68e-311 - - - E - - - amino acid
HKAHPFCC_01587 2.71e-181 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
HKAHPFCC_01588 1.72e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HKAHPFCC_01589 8.19e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
HKAHPFCC_01590 6.47e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HKAHPFCC_01591 3.22e-215 - - - GK - - - ROK family
HKAHPFCC_01592 0.0 fusA1 - - J - - - elongation factor G
HKAHPFCC_01593 7.46e-106 uspA3 - - T - - - universal stress protein
HKAHPFCC_01594 4.97e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HKAHPFCC_01595 4.37e-84 - - - - - - - -
HKAHPFCC_01596 3.18e-11 - - - - - - - -
HKAHPFCC_01597 6.26e-156 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HKAHPFCC_01598 4.99e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKAHPFCC_01599 1.18e-271 - - - EGP - - - Major Facilitator
HKAHPFCC_01600 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
HKAHPFCC_01601 4.33e-234 - - - C - - - Zinc-binding dehydrogenase
HKAHPFCC_01602 1.26e-209 - - - - - - - -
HKAHPFCC_01603 1.3e-95 - - - K - - - Transcriptional regulator
HKAHPFCC_01604 2.19e-214 ybcH - - D ko:K06889 - ko00000 Alpha beta
HKAHPFCC_01605 6.35e-69 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HKAHPFCC_01606 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HKAHPFCC_01607 6.5e-71 - - - - - - - -
HKAHPFCC_01608 1.5e-149 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HKAHPFCC_01609 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_01610 1.55e-129 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HKAHPFCC_01611 1.26e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
HKAHPFCC_01612 7.72e-178 - - - IQ - - - KR domain
HKAHPFCC_01613 1.1e-232 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HKAHPFCC_01614 1.51e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HKAHPFCC_01615 1.91e-164 - - - L ko:K07497 - ko00000 hmm pf00665
HKAHPFCC_01616 6.11e-111 - - - L - - - Helix-turn-helix domain
HKAHPFCC_01617 3.33e-33 - - - L - - - Helix-turn-helix domain
HKAHPFCC_01618 1.24e-37 - - - S - - - PD-(D/E)XK nuclease family transposase
HKAHPFCC_01619 4.01e-153 - - - S - - - HAD hydrolase, family IA, variant
HKAHPFCC_01620 0.0 yagE - - E - - - amino acid
HKAHPFCC_01621 2.93e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HKAHPFCC_01622 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HKAHPFCC_01623 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HKAHPFCC_01624 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKAHPFCC_01625 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKAHPFCC_01626 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKAHPFCC_01627 5.39e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKAHPFCC_01628 2.54e-268 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKAHPFCC_01629 1.06e-297 - - - - - - - -
HKAHPFCC_01630 5.29e-300 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HKAHPFCC_01631 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HKAHPFCC_01632 2.53e-97 - - - F - - - Nudix hydrolase
HKAHPFCC_01633 5.82e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HKAHPFCC_01634 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HKAHPFCC_01635 1.37e-40 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HKAHPFCC_01636 3.42e-195 - - - - - - - -
HKAHPFCC_01637 6.09e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HKAHPFCC_01638 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
HKAHPFCC_01639 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
HKAHPFCC_01640 1.76e-234 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKAHPFCC_01641 6.22e-10 - - - S - - - CsbD-like
HKAHPFCC_01642 1.34e-47 - - - S - - - Transglycosylase associated protein
HKAHPFCC_01643 1.58e-301 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKAHPFCC_01644 1.64e-162 pgm3 - - G - - - phosphoglycerate mutase
HKAHPFCC_01645 8.39e-151 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HKAHPFCC_01646 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HKAHPFCC_01647 3.87e-112 - - - - - - - -
HKAHPFCC_01649 7.69e-100 - - - - - - - -
HKAHPFCC_01650 1.74e-102 - - - - - - - -
HKAHPFCC_01651 9.86e-200 - - - - - - - -
HKAHPFCC_01653 3.22e-108 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKAHPFCC_01654 3.84e-60 - - - L - - - transposase and inactivated derivatives, IS30 family
HKAHPFCC_01655 6.19e-163 - - - L - - - PFAM Integrase catalytic region
HKAHPFCC_01656 4.74e-223 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HKAHPFCC_01657 6.37e-60 - - - - - - - -
HKAHPFCC_01658 7.98e-223 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HKAHPFCC_01659 8.69e-257 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HKAHPFCC_01660 2.26e-149 - - - S - - - Membrane
HKAHPFCC_01661 2.31e-163 - - - O - - - Zinc-dependent metalloprotease
HKAHPFCC_01662 1.62e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKAHPFCC_01663 1.58e-204 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HKAHPFCC_01665 1.27e-99 - - - L - - - PFAM Integrase catalytic region
HKAHPFCC_01667 2.66e-235 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HKAHPFCC_01668 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKAHPFCC_01669 4.54e-241 - - - - - - - -
HKAHPFCC_01670 3.88e-71 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKAHPFCC_01671 2.09e-268 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HKAHPFCC_01672 1.93e-210 - - - K - - - LysR substrate binding domain
HKAHPFCC_01673 1.54e-147 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HKAHPFCC_01674 4.01e-127 - - - K - - - acetyltransferase
HKAHPFCC_01675 1.66e-247 - - - - - - - -
HKAHPFCC_01677 2.78e-48 - - - L - - - Transposase
HKAHPFCC_01678 1.39e-105 - - - L - - - Transposase
HKAHPFCC_01679 7.47e-173 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
HKAHPFCC_01680 1.71e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HKAHPFCC_01681 1.95e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HKAHPFCC_01682 2.7e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HKAHPFCC_01683 3.14e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKAHPFCC_01684 8.65e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HKAHPFCC_01685 6.17e-202 - - - - - - - -
HKAHPFCC_01686 2.22e-313 - - - M - - - Glycosyl transferase
HKAHPFCC_01687 1.85e-288 - - - G - - - Glycosyl hydrolases family 8
HKAHPFCC_01688 3.28e-180 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HKAHPFCC_01689 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HKAHPFCC_01690 4.98e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HKAHPFCC_01691 2.8e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HKAHPFCC_01692 1.13e-108 - - - Q - - - Methyltransferase
HKAHPFCC_01693 4.85e-296 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HKAHPFCC_01694 9.78e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HKAHPFCC_01695 1.13e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HKAHPFCC_01696 9.06e-125 - - - S - - - NADPH-dependent FMN reductase
HKAHPFCC_01697 2.95e-157 - - - S - - - Conserved hypothetical protein 698
HKAHPFCC_01698 6.66e-177 - - - I - - - alpha/beta hydrolase fold
HKAHPFCC_01699 3.74e-212 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HKAHPFCC_01700 9.01e-132 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HKAHPFCC_01701 1.56e-229 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HKAHPFCC_01702 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
HKAHPFCC_01703 0.0 arcT - - E - - - Dipeptidase
HKAHPFCC_01704 5.43e-276 - - - EGP - - - Transporter, major facilitator family protein
HKAHPFCC_01705 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
HKAHPFCC_01706 1.43e-180 - - - V - - - Beta-lactamase enzyme family
HKAHPFCC_01707 2.79e-294 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HKAHPFCC_01708 5.36e-97 - - - - - - - -
HKAHPFCC_01709 8.05e-259 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HKAHPFCC_01710 1.19e-31 - - - - - - - -
HKAHPFCC_01711 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HKAHPFCC_01712 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
HKAHPFCC_01713 9.87e-266 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
HKAHPFCC_01714 8.22e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKAHPFCC_01715 1.3e-206 mleR - - K - - - LysR family
HKAHPFCC_01716 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HKAHPFCC_01717 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKAHPFCC_01718 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HKAHPFCC_01719 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HKAHPFCC_01720 5.08e-205 - - - K - - - LysR family
HKAHPFCC_01721 0.0 - - - S - - - Putative threonine/serine exporter
HKAHPFCC_01722 2.82e-154 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HKAHPFCC_01723 0.0 qacA - - EGP - - - Major Facilitator
HKAHPFCC_01724 1.16e-242 - - - I - - - Alpha beta
HKAHPFCC_01725 4.55e-121 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HKAHPFCC_01726 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKAHPFCC_01728 3.34e-212 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKAHPFCC_01729 6.51e-161 - - - S - - - Domain of unknown function (DUF4811)
HKAHPFCC_01730 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HKAHPFCC_01731 5.33e-98 - - - K - - - MerR HTH family regulatory protein
HKAHPFCC_01732 8.46e-77 - - - - - - - -
HKAHPFCC_01733 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKAHPFCC_01734 8.11e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKAHPFCC_01735 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKAHPFCC_01736 5.24e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKAHPFCC_01737 9.45e-196 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKAHPFCC_01738 1.39e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_01739 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
HKAHPFCC_01740 4.71e-142 - - - S - - - VIT family
HKAHPFCC_01741 3.11e-153 - - - S - - - membrane
HKAHPFCC_01742 1.72e-213 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HKAHPFCC_01743 2.32e-161 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HKAHPFCC_01744 2.17e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HKAHPFCC_01745 7.95e-171 - - - S - - - Putative threonine/serine exporter
HKAHPFCC_01746 2.59e-107 - - - S - - - Threonine/Serine exporter, ThrE
HKAHPFCC_01747 2.79e-153 - - - I - - - phosphatase
HKAHPFCC_01748 8.71e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HKAHPFCC_01749 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HKAHPFCC_01750 4.89e-203 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKAHPFCC_01751 2.45e-110 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKAHPFCC_01752 8.42e-47 - - - A ko:K12092 ko05120,map05120 ko00000,ko00001,ko00002,ko02044 chlorophyll binding
HKAHPFCC_01755 2.78e-100 - - - - - - - -
HKAHPFCC_01757 2.35e-106 - - - S - - - Bacteriophage holin family
HKAHPFCC_01758 1.5e-247 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HKAHPFCC_01759 8.65e-20 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HKAHPFCC_01760 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HKAHPFCC_01761 2.06e-125 - - - K - - - Acetyltransferase (GNAT) domain
HKAHPFCC_01762 1.1e-55 - - - - - - - -
HKAHPFCC_01763 1.81e-41 - - - - - - - -
HKAHPFCC_01764 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HKAHPFCC_01765 1.26e-60 - - - - - - - -
HKAHPFCC_01766 2.75e-105 - - - S - - - Protein of unknown function (DUF805)
HKAHPFCC_01767 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HKAHPFCC_01768 6.46e-131 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HKAHPFCC_01769 4.33e-146 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HKAHPFCC_01770 3.55e-231 - - - L - - - Belongs to the 'phage' integrase family
HKAHPFCC_01771 6.57e-239 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HKAHPFCC_01772 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HKAHPFCC_01773 1.5e-48 higA - - K ko:K21498 - ko00000,ko02048 addiction module antidote protein HigA
HKAHPFCC_01774 0.0 - - - L - - - PLD-like domain
HKAHPFCC_01776 3.42e-233 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HKAHPFCC_01777 1.19e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKAHPFCC_01778 3.2e-138 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HKAHPFCC_01779 1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HKAHPFCC_01780 2.33e-103 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKAHPFCC_01781 1.81e-146 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
HKAHPFCC_01782 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HKAHPFCC_01783 3.07e-265 - - - G - - - Transporter, major facilitator family protein
HKAHPFCC_01784 3.51e-142 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
HKAHPFCC_01785 4.73e-85 yuxO - - Q - - - Thioesterase superfamily
HKAHPFCC_01786 6.96e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HKAHPFCC_01787 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKAHPFCC_01788 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HKAHPFCC_01789 9.89e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HKAHPFCC_01790 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HKAHPFCC_01791 2.11e-308 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HKAHPFCC_01792 2.43e-303 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKAHPFCC_01793 9.11e-106 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HKAHPFCC_01794 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HKAHPFCC_01795 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
HKAHPFCC_01796 2e-207 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HKAHPFCC_01797 6.38e-151 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HKAHPFCC_01798 7.08e-52 - - - S - - - Cytochrome B5
HKAHPFCC_01799 4.21e-201 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HKAHPFCC_01800 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HKAHPFCC_01801 3.63e-190 - - - O - - - Band 7 protein
HKAHPFCC_01802 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
HKAHPFCC_01803 2.9e-169 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
HKAHPFCC_01804 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HKAHPFCC_01805 4.38e-161 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HKAHPFCC_01806 1.19e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HKAHPFCC_01807 1.7e-101 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HKAHPFCC_01808 4.28e-102 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HKAHPFCC_01809 1.12e-246 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
HKAHPFCC_01810 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HKAHPFCC_01811 8.22e-122 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HKAHPFCC_01812 1.31e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKAHPFCC_01813 4.11e-274 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HKAHPFCC_01814 1.74e-226 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HKAHPFCC_01815 1.09e-221 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HKAHPFCC_01816 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HKAHPFCC_01817 1.15e-115 ypmB - - S - - - Protein conserved in bacteria
HKAHPFCC_01818 2.48e-161 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HKAHPFCC_01819 2.42e-208 - - - EG - - - EamA-like transporter family
HKAHPFCC_01820 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HKAHPFCC_01821 1.21e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKAHPFCC_01822 1.17e-135 ypsA - - S - - - Belongs to the UPF0398 family
HKAHPFCC_01823 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKAHPFCC_01824 6.11e-111 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
HKAHPFCC_01825 6.84e-296 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HKAHPFCC_01826 7.66e-92 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HKAHPFCC_01827 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
HKAHPFCC_01828 8.85e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKAHPFCC_01829 7.11e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKAHPFCC_01830 1.93e-265 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HKAHPFCC_01831 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HKAHPFCC_01832 0.0 FbpA - - K - - - Fibronectin-binding protein
HKAHPFCC_01833 5.11e-208 - - - S - - - EDD domain protein, DegV family
HKAHPFCC_01834 7.18e-126 - - - - - - - -
HKAHPFCC_01835 1.29e-155 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKAHPFCC_01836 9.18e-206 gspA - - M - - - family 8
HKAHPFCC_01837 5.98e-206 - - - S - - - Alpha beta hydrolase
HKAHPFCC_01838 1.11e-123 - - - K - - - Acetyltransferase (GNAT) domain
HKAHPFCC_01841 2.16e-200 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HKAHPFCC_01842 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HKAHPFCC_01843 2.06e-193 yidA - - S - - - hydrolase
HKAHPFCC_01844 2.4e-102 - - - - - - - -
HKAHPFCC_01845 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKAHPFCC_01846 2.74e-316 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKAHPFCC_01847 2.09e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HKAHPFCC_01848 4.31e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HKAHPFCC_01849 4.85e-158 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HKAHPFCC_01850 5.16e-218 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HKAHPFCC_01851 1.71e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKAHPFCC_01852 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
HKAHPFCC_01853 3.73e-208 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKAHPFCC_01854 1.04e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKAHPFCC_01855 5.77e-201 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HKAHPFCC_01856 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKAHPFCC_01857 1.16e-208 yunF - - F - - - Protein of unknown function DUF72
HKAHPFCC_01859 1.51e-170 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HKAHPFCC_01860 1.33e-228 - - - - - - - -
HKAHPFCC_01861 1.98e-297 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HKAHPFCC_01862 2.53e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HKAHPFCC_01863 1.36e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HKAHPFCC_01864 5.96e-241 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
HKAHPFCC_01865 2.02e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HKAHPFCC_01866 0.0 - - - L - - - DNA helicase
HKAHPFCC_01867 1.1e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKAHPFCC_01869 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKAHPFCC_01870 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
HKAHPFCC_01871 4.89e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKAHPFCC_01872 3.07e-58 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
HKAHPFCC_01873 2.41e-280 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HKAHPFCC_01874 1.26e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HKAHPFCC_01875 5.28e-201 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HKAHPFCC_01876 1.04e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKAHPFCC_01877 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKAHPFCC_01878 6.12e-279 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HKAHPFCC_01879 0.0 eriC - - P ko:K03281 - ko00000 chloride
HKAHPFCC_01880 7.7e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HKAHPFCC_01881 6.84e-139 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HKAHPFCC_01882 6.38e-184 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_01883 2.86e-140 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKAHPFCC_01884 1.85e-209 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
HKAHPFCC_01885 1.07e-68 ywnA - - K - - - Transcriptional regulator
HKAHPFCC_01886 5.1e-204 - - - GM - - - NAD(P)H-binding
HKAHPFCC_01887 4.44e-11 - - - - - - - -
HKAHPFCC_01888 5.8e-291 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
HKAHPFCC_01889 0.0 cadA - - P - - - P-type ATPase
HKAHPFCC_01890 3e-167 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HKAHPFCC_01891 2.31e-166 - - - - - - - -
HKAHPFCC_01892 2.84e-73 - - - S - - - Sugar efflux transporter for intercellular exchange
HKAHPFCC_01893 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HKAHPFCC_01895 0.0 - - - L - - - Helicase C-terminal domain protein
HKAHPFCC_01896 1.31e-109 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
HKAHPFCC_01897 3.04e-233 ydhF - - S - - - Aldo keto reductase
HKAHPFCC_01899 6.12e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKAHPFCC_01900 6.25e-83 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HKAHPFCC_01901 3.04e-133 - - - S ko:K07002 - ko00000 Serine hydrolase
HKAHPFCC_01903 1.2e-63 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKAHPFCC_01904 1.86e-136 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKAHPFCC_01905 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HKAHPFCC_01906 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
HKAHPFCC_01907 1.39e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HKAHPFCC_01908 2.33e-51 - - - - - - - -
HKAHPFCC_01909 1.89e-171 - - - IQ - - - dehydrogenase reductase
HKAHPFCC_01910 1.05e-309 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
HKAHPFCC_01911 1.07e-52 hxlR - - K - - - regulation of RNA biosynthetic process
HKAHPFCC_01912 2.09e-213 - - - G - - - Belongs to the carbohydrate kinase PfkB family
HKAHPFCC_01913 0.0 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HKAHPFCC_01914 2.34e-266 - - - O - - - ADP-ribosylglycohydrolase
HKAHPFCC_01915 6.36e-136 pncA - - Q - - - Isochorismatase family
HKAHPFCC_01916 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKAHPFCC_01917 1.69e-170 - - - F - - - NUDIX domain
HKAHPFCC_01918 1.14e-300 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HKAHPFCC_01919 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKAHPFCC_01920 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKAHPFCC_01921 2.59e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HKAHPFCC_01922 4.1e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKAHPFCC_01923 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKAHPFCC_01924 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HKAHPFCC_01925 2.07e-237 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HKAHPFCC_01926 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKAHPFCC_01927 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKAHPFCC_01928 1.09e-295 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HKAHPFCC_01929 9.51e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HKAHPFCC_01930 3.6e-158 radC - - L ko:K03630 - ko00000 DNA repair protein
HKAHPFCC_01931 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HKAHPFCC_01932 7.72e-195 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HKAHPFCC_01933 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HKAHPFCC_01934 3.13e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HKAHPFCC_01935 1.45e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKAHPFCC_01936 2.84e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HKAHPFCC_01937 3.68e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
HKAHPFCC_01938 0.0 ymfH - - S - - - Peptidase M16
HKAHPFCC_01939 7.21e-198 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HKAHPFCC_01940 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKAHPFCC_01941 6.36e-296 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HKAHPFCC_01942 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKAHPFCC_01943 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HKAHPFCC_01944 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKAHPFCC_01945 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKAHPFCC_01946 4.52e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKAHPFCC_01947 9.97e-245 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKAHPFCC_01948 1.11e-260 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKAHPFCC_01949 1.86e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HKAHPFCC_01950 2.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HKAHPFCC_01951 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKAHPFCC_01952 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKAHPFCC_01953 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
HKAHPFCC_01954 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKAHPFCC_01955 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
HKAHPFCC_01956 7.15e-122 cvpA - - S - - - Colicin V production protein
HKAHPFCC_01957 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKAHPFCC_01958 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HKAHPFCC_01959 3.01e-126 yslB - - S - - - Protein of unknown function (DUF2507)
HKAHPFCC_01960 3.41e-189 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HKAHPFCC_01961 1.53e-138 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKAHPFCC_01962 1.16e-124 - - - S ko:K07095 - ko00000 Phosphoesterase
HKAHPFCC_01963 1.79e-100 ykuL - - S - - - (CBS) domain
HKAHPFCC_01964 1.4e-198 - - - S - - - haloacid dehalogenase-like hydrolase
HKAHPFCC_01965 1.6e-190 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HKAHPFCC_01966 1.54e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKAHPFCC_01967 2.93e-58 - - - - - - - -
HKAHPFCC_01968 6.25e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HKAHPFCC_01969 1.7e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HKAHPFCC_01970 1.03e-181 - - - - - - - -
HKAHPFCC_01971 1.22e-168 yebC - - K - - - Transcriptional regulatory protein
HKAHPFCC_01972 8.77e-237 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HKAHPFCC_01973 2.95e-240 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HKAHPFCC_01974 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HKAHPFCC_01975 3.65e-103 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HKAHPFCC_01976 3.65e-60 - - - - - - - -
HKAHPFCC_01977 1.01e-95 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
HKAHPFCC_01979 3.58e-186 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HKAHPFCC_01980 1.36e-286 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKAHPFCC_01981 6.01e-153 - - - S - - - Calcineurin-like phosphoesterase
HKAHPFCC_01982 3.03e-129 yutD - - S - - - Protein of unknown function (DUF1027)
HKAHPFCC_01983 1.44e-180 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKAHPFCC_01984 7.15e-148 - - - S - - - Protein of unknown function (DUF1461)
HKAHPFCC_01985 1.29e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)