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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
GNFHJPHE_00001	1.15e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GNFHJPHE_00002	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
GNFHJPHE_00003	6.64e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GNFHJPHE_00004	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GNFHJPHE_00005	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GNFHJPHE_00006	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
GNFHJPHE_00007	1.34e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GNFHJPHE_00008	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GNFHJPHE_00009	1.31e-97	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GNFHJPHE_00010	6.39e-23	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
GNFHJPHE_00011	1.14e-66	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
GNFHJPHE_00012	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
GNFHJPHE_00013	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GNFHJPHE_00014	7.36e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
GNFHJPHE_00015	2.17e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
GNFHJPHE_00016	7.71e-81	-	-	-	-	-	-	-	-
GNFHJPHE_00017	2.53e-208	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
GNFHJPHE_00018	5.2e-156	-	-	-	S	-	-	-	Fic/DOC family
GNFHJPHE_00020	1.55e-95	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
GNFHJPHE_00021	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
GNFHJPHE_00023	3.4e-166	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
GNFHJPHE_00024	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFHJPHE_00025	1.89e-312	yycH	-	-	S	-	-	-	YycH protein
GNFHJPHE_00026	2.05e-192	yycI	-	-	S	-	-	-	YycH protein
GNFHJPHE_00027	1.46e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
GNFHJPHE_00028	7.56e-286	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
GNFHJPHE_00030	1.47e-110	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
GNFHJPHE_00031	1e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
GNFHJPHE_00032	7.54e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GNFHJPHE_00034	1.56e-125	-	-	-	S	-	-	-	reductase
GNFHJPHE_00035	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
GNFHJPHE_00036	5.67e-198	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
GNFHJPHE_00037	1.52e-192	-	-	-	E	-	-	-	Glyoxalase-like domain
GNFHJPHE_00038	2.13e-189	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GNFHJPHE_00039	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
GNFHJPHE_00040	1.36e-198	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GNFHJPHE_00041	3.99e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
GNFHJPHE_00042	1.31e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
GNFHJPHE_00043	1.35e-45	-	-	-	-	-	-	-	-
GNFHJPHE_00044	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
GNFHJPHE_00047	3.99e-68	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GNFHJPHE_00048	1.79e-111	-	-	-	K	-	-	-	FR47-like protein
GNFHJPHE_00049	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
GNFHJPHE_00050	4.23e-222	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNFHJPHE_00051	1.13e-272	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GNFHJPHE_00052	2.49e-43	-	-	-	-	-	-	-	-
GNFHJPHE_00053	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
GNFHJPHE_00055	3.76e-134	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
GNFHJPHE_00056	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GNFHJPHE_00057	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GNFHJPHE_00058	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
GNFHJPHE_00059	5.18e-222	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
GNFHJPHE_00060	2.2e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
GNFHJPHE_00061	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GNFHJPHE_00062	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
GNFHJPHE_00063	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
GNFHJPHE_00064	5.97e-92	-	-	-	-	-	-	-	-
GNFHJPHE_00065	1.02e-111	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
GNFHJPHE_00066	3.15e-153	dltr	-	-	K	-	-	-	response regulator
GNFHJPHE_00067	7.94e-290	sptS	-	-	T	-	-	-	Histidine kinase
GNFHJPHE_00068	4.12e-274	-	-	-	P	-	-	-	Voltage gated chloride channel
GNFHJPHE_00069	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
GNFHJPHE_00070	2.5e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
GNFHJPHE_00071	2.1e-214	-	-	-	C	-	-	-	Aldo keto reductase
GNFHJPHE_00072	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
GNFHJPHE_00073	6.51e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
GNFHJPHE_00074	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
GNFHJPHE_00075	2.95e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GNFHJPHE_00076	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GNFHJPHE_00077	3.46e-114	-	-	-	-	-	-	-	-
GNFHJPHE_00078	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GNFHJPHE_00080	1.11e-16	-	-	-	E	-	-	-	amino acid
GNFHJPHE_00081	2.53e-17	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
GNFHJPHE_00082	6.53e-96	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
GNFHJPHE_00083	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_00084	8.53e-95	-	-	-	-	-	-	-	-
GNFHJPHE_00085	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GNFHJPHE_00086	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
GNFHJPHE_00087	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
GNFHJPHE_00088	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
GNFHJPHE_00089	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GNFHJPHE_00090	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_00091	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GNFHJPHE_00092	6.68e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GNFHJPHE_00093	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GNFHJPHE_00094	3.48e-225	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
GNFHJPHE_00095	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GNFHJPHE_00096	3.33e-129	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
GNFHJPHE_00097	6.57e-262	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
GNFHJPHE_00098	5.64e-225	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GNFHJPHE_00099	5.2e-35	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_00101	1.67e-45	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_00102	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GNFHJPHE_00103	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_00104	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GNFHJPHE_00105	1.9e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_00106	1.02e-284	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GNFHJPHE_00107	2.4e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
GNFHJPHE_00108	1.43e-219	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
GNFHJPHE_00109	1.47e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
GNFHJPHE_00110	3.34e-158	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
GNFHJPHE_00111	7.65e-193	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GNFHJPHE_00112	8.34e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
GNFHJPHE_00113	8e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GNFHJPHE_00114	2.37e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
GNFHJPHE_00115	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GNFHJPHE_00116	8.95e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
GNFHJPHE_00117	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GNFHJPHE_00118	3.81e-297	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GNFHJPHE_00119	2.24e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
GNFHJPHE_00120	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
GNFHJPHE_00121	3.92e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
GNFHJPHE_00122	1.47e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GNFHJPHE_00123	9.76e-161	vanR	-	-	K	-	-	-	response regulator
GNFHJPHE_00124	3.73e-264	hpk31	-	-	T	-	-	-	Histidine kinase
GNFHJPHE_00125	9.75e-186	-	-	-	E	-	-	-	AzlC protein
GNFHJPHE_00126	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
GNFHJPHE_00127	2.63e-164	-	-	-	K	-	-	-	LysR substrate binding domain
GNFHJPHE_00128	2.57e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
GNFHJPHE_00129	3.53e-312	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GNFHJPHE_00130	1.95e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GNFHJPHE_00131	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GNFHJPHE_00132	1.51e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GNFHJPHE_00133	6.14e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
GNFHJPHE_00134	1.52e-121	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GNFHJPHE_00135	1.11e-289	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
GNFHJPHE_00136	3.86e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
GNFHJPHE_00137	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
GNFHJPHE_00138	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GNFHJPHE_00139	1.05e-164	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
GNFHJPHE_00140	5.74e-24	mocA	-	-	S	-	-	-	Oxidoreductase
GNFHJPHE_00141	1.36e-30	rhaS4	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GNFHJPHE_00142	5.9e-231	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
GNFHJPHE_00143	3.61e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
GNFHJPHE_00144	8.62e-128	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GNFHJPHE_00145	1.43e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GNFHJPHE_00146	5.01e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GNFHJPHE_00147	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GNFHJPHE_00148	5.23e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
GNFHJPHE_00149	4.5e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GNFHJPHE_00150	1.98e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GNFHJPHE_00151	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GNFHJPHE_00152	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GNFHJPHE_00153	4.6e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
GNFHJPHE_00154	2.37e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GNFHJPHE_00155	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
GNFHJPHE_00156	2.36e-309	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
GNFHJPHE_00157	2.15e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GNFHJPHE_00158	1.12e-226	-	-	-	-	-	-	-	-
GNFHJPHE_00159	6.7e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GNFHJPHE_00161	6.17e-54	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_00162	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
GNFHJPHE_00163	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GNFHJPHE_00164	1.63e-81	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GNFHJPHE_00165	2.52e-68	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNFHJPHE_00166	2.46e-108	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNFHJPHE_00167	1.69e-267	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
GNFHJPHE_00168	2.83e-227	-	-	-	S	-	-	-	FRG
GNFHJPHE_00169	3.48e-133	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GNFHJPHE_00170	1.99e-216	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GNFHJPHE_00171	3.35e-59	-	-	-	S	-	-	-	Pfam:DUF59
GNFHJPHE_00172	4.48e-90	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GNFHJPHE_00173	3.32e-95	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_00174	1.85e-78	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_00175	2.76e-84	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFHJPHE_00176	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
GNFHJPHE_00177	9.63e-306	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
GNFHJPHE_00178	8.25e-166	-	-	-	IQ	-	-	-	dehydrogenase reductase
GNFHJPHE_00179	1.3e-48	-	-	-	-	-	-	-	-
GNFHJPHE_00180	1.56e-146	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
GNFHJPHE_00181	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
GNFHJPHE_00182	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
GNFHJPHE_00183	1.62e-231	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GNFHJPHE_00185	1.9e-127	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
GNFHJPHE_00186	6.75e-34	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
GNFHJPHE_00187	1.44e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GNFHJPHE_00189	6.6e-228	ydhF	-	-	S	-	-	-	Aldo keto reductase
GNFHJPHE_00190	9.9e-105	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
GNFHJPHE_00191	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
GNFHJPHE_00193	4.48e-312	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
GNFHJPHE_00194	1.85e-69	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
GNFHJPHE_00195	8.65e-162	-	-	-	-	-	-	-	-
GNFHJPHE_00196	2.27e-162	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
GNFHJPHE_00197	0.0	cadA	-	-	P	-	-	-	P-type ATPase
GNFHJPHE_00198	5.7e-280	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
GNFHJPHE_00199	4.44e-11	-	-	-	-	-	-	-	-
GNFHJPHE_00200	1.89e-45	-	-	-	GM	-	-	-	NAD(P)H-binding
GNFHJPHE_00201	7.59e-66	-	-	-	GM	-	-	-	NAD(P)H-binding
GNFHJPHE_00202	2.24e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
GNFHJPHE_00203	1.85e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
GNFHJPHE_00204	3.2e-137	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GNFHJPHE_00205	1.23e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_00206	1.32e-136	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
GNFHJPHE_00207	7.7e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
GNFHJPHE_00208	7.41e-83	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_00209	2.48e-274	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_00210	1.63e-238	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GNFHJPHE_00211	2.1e-270	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
GNFHJPHE_00212	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GNFHJPHE_00213	3.47e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GNFHJPHE_00214	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GNFHJPHE_00215	4.93e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
GNFHJPHE_00216	5.93e-281	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
GNFHJPHE_00217	5.74e-54	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
GNFHJPHE_00218	2.83e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GNFHJPHE_00219	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
GNFHJPHE_00220	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GNFHJPHE_00222	7.77e-261	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GNFHJPHE_00223	0.0	-	-	-	L	-	-	-	DNA helicase
GNFHJPHE_00224	4.08e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
GNFHJPHE_00225	8.74e-234	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
GNFHJPHE_00226	9.18e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GNFHJPHE_00227	3.08e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
GNFHJPHE_00228	9.64e-289	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
GNFHJPHE_00229	1.74e-224	-	-	-	-	-	-	-	-
GNFHJPHE_00230	2.81e-166	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
GNFHJPHE_00232	3.2e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
GNFHJPHE_00233	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GNFHJPHE_00234	3.58e-198	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
GNFHJPHE_00235	7.04e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GNFHJPHE_00236	8.07e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GNFHJPHE_00237	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
GNFHJPHE_00238	1.71e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GNFHJPHE_00239	2.26e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GNFHJPHE_00240	1.98e-157	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GNFHJPHE_00241	6.12e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
GNFHJPHE_00242	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
GNFHJPHE_00243	3.04e-312	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GNFHJPHE_00244	2.04e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GNFHJPHE_00245	8.76e-303	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
GNFHJPHE_00246	1.19e-98	-	-	-	-	-	-	-	-
GNFHJPHE_00247	3.14e-188	yidA	-	-	S	-	-	-	hydrolase
GNFHJPHE_00248	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
GNFHJPHE_00249	3.54e-190	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
GNFHJPHE_00250	3.15e-71	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
GNFHJPHE_00251	2.44e-84	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GNFHJPHE_00252	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GNFHJPHE_00253	1.11e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GNFHJPHE_00254	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
GNFHJPHE_00255	2.16e-301	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GNFHJPHE_00256	1.78e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GNFHJPHE_00257	1.18e-159	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
GNFHJPHE_00258	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GNFHJPHE_00259	3.7e-192	-	-	-	G	-	-	-	Right handed beta helix region
GNFHJPHE_00260	8.28e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GNFHJPHE_00261	5.32e-208	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
GNFHJPHE_00262	1.84e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
GNFHJPHE_00263	5.7e-114	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GNFHJPHE_00264	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
GNFHJPHE_00265	3.7e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
GNFHJPHE_00266	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GNFHJPHE_00267	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GNFHJPHE_00268	1.57e-195	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GNFHJPHE_00269	1.56e-212	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
GNFHJPHE_00270	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GNFHJPHE_00271	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFHJPHE_00272	1.1e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
GNFHJPHE_00273	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GNFHJPHE_00274	4.54e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
GNFHJPHE_00275	8.96e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GNFHJPHE_00276	1.41e-265	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GNFHJPHE_00277	5.31e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
GNFHJPHE_00278	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
GNFHJPHE_00279	1.59e-308	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
GNFHJPHE_00280	3.27e-185	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
GNFHJPHE_00281	3.29e-146	-	-	-	S	-	-	-	(CBS) domain
GNFHJPHE_00282	9.32e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GNFHJPHE_00283	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GNFHJPHE_00284	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
GNFHJPHE_00285	4.14e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
GNFHJPHE_00286	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
GNFHJPHE_00287	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GNFHJPHE_00288	8.67e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
GNFHJPHE_00289	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GNFHJPHE_00290	3.1e-216	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GNFHJPHE_00291	6.21e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GNFHJPHE_00292	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
GNFHJPHE_00293	6.04e-109	-	-	-	-	-	-	-	-
GNFHJPHE_00297	2.4e-19	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
GNFHJPHE_00299	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
GNFHJPHE_00300	4.13e-190	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GNFHJPHE_00303	1.09e-143	-	-	-	-	-	-	-	-
GNFHJPHE_00304	1.61e-315	-	-	-	EGP	-	-	-	Major Facilitator
GNFHJPHE_00305	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
GNFHJPHE_00306	1.18e-166	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
GNFHJPHE_00307	5.03e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
GNFHJPHE_00308	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GNFHJPHE_00309	1.45e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GNFHJPHE_00310	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
GNFHJPHE_00311	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
GNFHJPHE_00313	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
GNFHJPHE_00314	5.05e-233	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
GNFHJPHE_00315	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
GNFHJPHE_00316	2.92e-170	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GNFHJPHE_00317	4.95e-213	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GNFHJPHE_00318	8.63e-274	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
GNFHJPHE_00319	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GNFHJPHE_00320	1.01e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_00321	1.95e-177	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
GNFHJPHE_00322	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
GNFHJPHE_00323	1.45e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GNFHJPHE_00324	4.04e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
GNFHJPHE_00325	8.07e-128	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
GNFHJPHE_00326	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GNFHJPHE_00327	9.5e-263	yacL	-	-	S	-	-	-	domain protein
GNFHJPHE_00328	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GNFHJPHE_00329	2.95e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GNFHJPHE_00330	7.41e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GNFHJPHE_00331	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GNFHJPHE_00332	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GNFHJPHE_00333	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
GNFHJPHE_00334	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GNFHJPHE_00335	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GNFHJPHE_00336	4.39e-287	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
GNFHJPHE_00337	2.66e-272	-	-	-	M	-	-	-	Glycosyl transferase family group 2
GNFHJPHE_00338	1.26e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GNFHJPHE_00339	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GNFHJPHE_00340	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GNFHJPHE_00341	8.34e-65	-	-	-	-	-	-	-	-
GNFHJPHE_00343	3.29e-62	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GNFHJPHE_00344	4.63e-74	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
GNFHJPHE_00345	2.57e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
GNFHJPHE_00346	9.28e-170	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
GNFHJPHE_00347	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
GNFHJPHE_00348	7.68e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GNFHJPHE_00349	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GNFHJPHE_00350	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
GNFHJPHE_00351	1.16e-114	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GNFHJPHE_00352	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GNFHJPHE_00353	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GNFHJPHE_00354	1.65e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GNFHJPHE_00355	2.71e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
GNFHJPHE_00356	1.97e-143	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GNFHJPHE_00357	1.64e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
GNFHJPHE_00358	1.02e-232	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GNFHJPHE_00359	1.77e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
GNFHJPHE_00360	1.76e-197	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GNFHJPHE_00361	9.68e-173	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
GNFHJPHE_00362	1.41e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_00363	4.42e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_00364	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
GNFHJPHE_00365	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GNFHJPHE_00366	5.13e-219	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
GNFHJPHE_00367	5.54e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
GNFHJPHE_00368	1.04e-161	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
GNFHJPHE_00369	8e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
GNFHJPHE_00370	3.23e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GNFHJPHE_00371	1.47e-169	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GNFHJPHE_00372	6.03e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GNFHJPHE_00373	1.48e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GNFHJPHE_00374	8.63e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
GNFHJPHE_00375	5.13e-288	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GNFHJPHE_00376	4.85e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNFHJPHE_00377	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
GNFHJPHE_00378	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GNFHJPHE_00380	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GNFHJPHE_00381	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GNFHJPHE_00382	7.03e-103	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
GNFHJPHE_00383	0.0	-	-	-	E	-	-	-	amino acid
GNFHJPHE_00384	0.0	ydaO	-	-	E	-	-	-	amino acid
GNFHJPHE_00385	1.53e-52	-	-	-	-	-	-	-	-
GNFHJPHE_00386	5.12e-132	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GNFHJPHE_00387	1.02e-139	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
GNFHJPHE_00388	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
GNFHJPHE_00389	4.08e-147	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
GNFHJPHE_00390	3.01e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GNFHJPHE_00391	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GNFHJPHE_00392	1.3e-237	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GNFHJPHE_00393	4.27e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
GNFHJPHE_00394	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
GNFHJPHE_00395	3.96e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GNFHJPHE_00396	9.5e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GNFHJPHE_00397	9.42e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
GNFHJPHE_00398	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
GNFHJPHE_00399	8.71e-176	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
GNFHJPHE_00400	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
GNFHJPHE_00401	3.22e-214	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
GNFHJPHE_00402	1.37e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GNFHJPHE_00403	7.43e-259	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
GNFHJPHE_00404	2.83e-206	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
GNFHJPHE_00405	9.93e-115	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
GNFHJPHE_00406	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GNFHJPHE_00407	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
GNFHJPHE_00408	2.12e-19	-	-	-	-	-	-	-	-
GNFHJPHE_00409	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GNFHJPHE_00410	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GNFHJPHE_00411	3.67e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
GNFHJPHE_00412	1.63e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
GNFHJPHE_00413	1.11e-236	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
GNFHJPHE_00414	1.59e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
GNFHJPHE_00416	1.83e-21	-	-	-	-	-	-	-	-
GNFHJPHE_00417	2.74e-171	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_00418	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GNFHJPHE_00420	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GNFHJPHE_00421	4.41e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
GNFHJPHE_00422	1.45e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GNFHJPHE_00423	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GNFHJPHE_00424	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
GNFHJPHE_00425	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GNFHJPHE_00426	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GNFHJPHE_00427	2.49e-182	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
GNFHJPHE_00428	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GNFHJPHE_00429	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GNFHJPHE_00430	6.49e-135	-	-	-	-	-	-	-	-
GNFHJPHE_00431	7.51e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GNFHJPHE_00432	2.79e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
GNFHJPHE_00433	1.2e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
GNFHJPHE_00434	6.2e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GNFHJPHE_00435	2.06e-98	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
GNFHJPHE_00436	2.5e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GNFHJPHE_00437	1.31e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
GNFHJPHE_00438	1.57e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GNFHJPHE_00439	8.28e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GNFHJPHE_00440	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
GNFHJPHE_00441	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GNFHJPHE_00442	5.7e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
GNFHJPHE_00443	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GNFHJPHE_00444	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GNFHJPHE_00445	3e-69	-	-	-	-	-	-	-	-
GNFHJPHE_00446	0.0	oatA	-	-	I	-	-	-	Acyltransferase
GNFHJPHE_00447	6.2e-103	-	-	-	K	-	-	-	Transcriptional regulator
GNFHJPHE_00448	5.46e-191	-	-	-	S	-	-	-	Cof-like hydrolase
GNFHJPHE_00449	6.22e-107	lytE	-	-	M	-	-	-	Lysin motif
GNFHJPHE_00451	4e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
GNFHJPHE_00452	0.0	yclK	-	-	T	-	-	-	Histidine kinase
GNFHJPHE_00453	2.14e-197	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
GNFHJPHE_00454	1.11e-140	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
GNFHJPHE_00455	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
GNFHJPHE_00456	1.1e-35	-	-	-	-	-	-	-	-
GNFHJPHE_00457	1.24e-221	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_00459	3.42e-41	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
GNFHJPHE_00460	1.06e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
GNFHJPHE_00461	5.33e-243	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GNFHJPHE_00462	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
GNFHJPHE_00463	1.62e-203	-	-	-	EG	-	-	-	EamA-like transporter family
GNFHJPHE_00464	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
GNFHJPHE_00465	4.39e-71	-	-	-	S	-	-	-	Cupredoxin-like domain
GNFHJPHE_00466	5.2e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
GNFHJPHE_00467	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
GNFHJPHE_00468	1.75e-110	-	-	-	-	-	-	-	-
GNFHJPHE_00470	1.5e-74	-	-	-	-	-	-	-	-
GNFHJPHE_00471	6.5e-184	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GNFHJPHE_00472	2.16e-58	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GNFHJPHE_00474	1.6e-132	-	-	-	-	-	-	-	-
GNFHJPHE_00475	2.83e-123	-	-	-	M	-	-	-	domain protein
GNFHJPHE_00476	2.21e-176	-	-	-	M	-	-	-	domain protein
GNFHJPHE_00477	2.05e-171	-	-	-	M	-	-	-	domain protein
GNFHJPHE_00478	1.41e-71	-	-	-	M	-	-	-	domain protein
GNFHJPHE_00479	3.5e-64	-	-	-	-	-	-	-	-
GNFHJPHE_00480	8.72e-235	ampC	-	-	V	-	-	-	Beta-lactamase
GNFHJPHE_00481	1.96e-292	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
GNFHJPHE_00482	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
GNFHJPHE_00483	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
GNFHJPHE_00484	6.27e-294	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
GNFHJPHE_00485	3.29e-171	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
GNFHJPHE_00486	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
GNFHJPHE_00487	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
GNFHJPHE_00488	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GNFHJPHE_00489	5.54e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GNFHJPHE_00490	1.55e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GNFHJPHE_00491	1.22e-291	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GNFHJPHE_00492	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GNFHJPHE_00493	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GNFHJPHE_00494	3.33e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
GNFHJPHE_00495	4.04e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
GNFHJPHE_00496	2.57e-292	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
GNFHJPHE_00497	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
GNFHJPHE_00498	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GNFHJPHE_00499	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GNFHJPHE_00500	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GNFHJPHE_00501	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GNFHJPHE_00502	4.34e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GNFHJPHE_00503	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GNFHJPHE_00504	2.11e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
GNFHJPHE_00505	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
GNFHJPHE_00506	4.97e-307	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GNFHJPHE_00507	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
GNFHJPHE_00508	3.77e-56	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
GNFHJPHE_00509	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
GNFHJPHE_00510	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
GNFHJPHE_00511	8.55e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
GNFHJPHE_00512	7.38e-274	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
GNFHJPHE_00513	2.12e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GNFHJPHE_00514	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
GNFHJPHE_00515	5.13e-61	-	-	-	-	-	-	-	-
GNFHJPHE_00516	6.29e-308	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
GNFHJPHE_00517	8.27e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
GNFHJPHE_00518	9.32e-27	-	-	-	-	-	-	-	-
GNFHJPHE_00519	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
GNFHJPHE_00520	4.16e-180	-	-	-	S	-	-	-	Membrane
GNFHJPHE_00521	8.05e-179	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
GNFHJPHE_00522	1.23e-233	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GNFHJPHE_00523	1.23e-41	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GNFHJPHE_00524	4.52e-39	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GNFHJPHE_00525	3.32e-38	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GNFHJPHE_00526	1.25e-177	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_00527	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GNFHJPHE_00528	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GNFHJPHE_00529	7.1e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GNFHJPHE_00530	2.37e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GNFHJPHE_00531	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GNFHJPHE_00532	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
GNFHJPHE_00533	5.45e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
GNFHJPHE_00534	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GNFHJPHE_00535	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GNFHJPHE_00536	2.58e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
GNFHJPHE_00537	9.28e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
GNFHJPHE_00538	4.2e-157	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
GNFHJPHE_00539	4.82e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
GNFHJPHE_00540	3.82e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
GNFHJPHE_00541	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
GNFHJPHE_00542	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GNFHJPHE_00543	1.45e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_00544	3.32e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
GNFHJPHE_00545	6.25e-287	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
GNFHJPHE_00546	2.6e-315	ymfH	-	-	S	-	-	-	Peptidase M16
GNFHJPHE_00547	4.4e-192	-	-	-	S	-	-	-	Helix-turn-helix domain
GNFHJPHE_00548	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GNFHJPHE_00549	1.6e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
GNFHJPHE_00550	3.64e-250	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GNFHJPHE_00551	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
GNFHJPHE_00552	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GNFHJPHE_00553	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GNFHJPHE_00554	4.34e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GNFHJPHE_00555	3.34e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GNFHJPHE_00556	2.41e-239	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GNFHJPHE_00557	2.05e-59	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GNFHJPHE_00558	1.24e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
GNFHJPHE_00559	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GNFHJPHE_00560	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GNFHJPHE_00561	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
GNFHJPHE_00562	8.55e-99	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GNFHJPHE_00563	1.08e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
GNFHJPHE_00564	1.44e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
GNFHJPHE_00565	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GNFHJPHE_00566	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
GNFHJPHE_00567	5.82e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
GNFHJPHE_00568	6.89e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
GNFHJPHE_00569	4.22e-136	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GNFHJPHE_00570	1.65e-120	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
GNFHJPHE_00571	8.55e-99	ykuL	-	-	S	-	-	-	(CBS) domain
GNFHJPHE_00572	1.83e-196	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GNFHJPHE_00573	7.58e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
GNFHJPHE_00574	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GNFHJPHE_00575	2.04e-72	-	-	-	-	-	-	-	-
GNFHJPHE_00576	4.92e-266	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GNFHJPHE_00577	7.72e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
GNFHJPHE_00578	1.05e-174	-	-	-	-	-	-	-	-
GNFHJPHE_00579	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
GNFHJPHE_00580	1.56e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
GNFHJPHE_00581	6.11e-233	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
GNFHJPHE_00582	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
GNFHJPHE_00583	2.12e-102	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
GNFHJPHE_00584	1.96e-55	-	-	-	-	-	-	-	-
GNFHJPHE_00585	1.88e-91	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
GNFHJPHE_00586	1.15e-182	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
GNFHJPHE_00587	4.36e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GNFHJPHE_00588	1.21e-143	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GNFHJPHE_00589	2.66e-120	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
GNFHJPHE_00590	6.76e-170	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GNFHJPHE_00591	2.94e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
GNFHJPHE_00592	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
GNFHJPHE_00615	4.46e-87	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
GNFHJPHE_00616	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
GNFHJPHE_00617	5.33e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
GNFHJPHE_00618	2.87e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GNFHJPHE_00619	4.29e-152	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GNFHJPHE_00620	6.57e-253	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
GNFHJPHE_00621	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GNFHJPHE_00622	3.29e-146	yjbH	-	-	Q	-	-	-	Thioredoxin
GNFHJPHE_00623	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
GNFHJPHE_00624	1.7e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GNFHJPHE_00625	9.29e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GNFHJPHE_00630	2.8e-81	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
GNFHJPHE_00631	3.44e-12	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
GNFHJPHE_00632	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
GNFHJPHE_00634	2.67e-251	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
GNFHJPHE_00635	6.7e-205	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
GNFHJPHE_00636	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GNFHJPHE_00637	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
GNFHJPHE_00638	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
GNFHJPHE_00639	2.32e-75	-	-	-	-	-	-	-	-
GNFHJPHE_00640	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
GNFHJPHE_00641	4.95e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GNFHJPHE_00642	9.94e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
GNFHJPHE_00643	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GNFHJPHE_00644	7.41e-228	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GNFHJPHE_00645	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GNFHJPHE_00646	1.98e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GNFHJPHE_00647	5.77e-184	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GNFHJPHE_00648	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GNFHJPHE_00649	8.44e-284	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GNFHJPHE_00650	6.41e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GNFHJPHE_00651	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
GNFHJPHE_00652	1.76e-188	ylmH	-	-	S	-	-	-	S4 domain protein
GNFHJPHE_00653	3.1e-101	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
GNFHJPHE_00654	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GNFHJPHE_00655	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
GNFHJPHE_00656	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
GNFHJPHE_00657	1.19e-25	-	-	-	-	-	-	-	-
GNFHJPHE_00658	4.64e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GNFHJPHE_00659	1.1e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GNFHJPHE_00660	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
GNFHJPHE_00661	6.17e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GNFHJPHE_00662	5.71e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
GNFHJPHE_00663	5.21e-155	-	-	-	S	-	-	-	repeat protein
GNFHJPHE_00664	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GNFHJPHE_00665	1.42e-221	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GNFHJPHE_00666	2.6e-233	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GNFHJPHE_00667	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GNFHJPHE_00668	3.81e-310	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GNFHJPHE_00669	4.39e-110	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GNFHJPHE_00670	2.32e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GNFHJPHE_00671	1.32e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GNFHJPHE_00672	1.56e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GNFHJPHE_00673	5.91e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GNFHJPHE_00674	4.47e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GNFHJPHE_00675	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
GNFHJPHE_00676	2e-179	-	-	-	L	-	-	-	Integrase core domain
GNFHJPHE_00677	7.04e-88	-	-	-	L	-	-	-	Integrase core domain
GNFHJPHE_00678	8.3e-96	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
GNFHJPHE_00679	3.83e-280	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
GNFHJPHE_00680	5.31e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
GNFHJPHE_00681	2.15e-75	-	-	-	-	-	-	-	-
GNFHJPHE_00683	1.57e-213	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
GNFHJPHE_00684	4.37e-39	-	-	-	-	-	-	-	-
GNFHJPHE_00685	7.16e-231	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
GNFHJPHE_00686	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
GNFHJPHE_00687	4.42e-101	-	-	-	-	-	-	-	-
GNFHJPHE_00688	2.78e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GNFHJPHE_00689	9.54e-265	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
GNFHJPHE_00690	3.83e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
GNFHJPHE_00691	1.23e-310	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GNFHJPHE_00692	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
GNFHJPHE_00693	1.32e-59	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
GNFHJPHE_00694	4.59e-173	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
GNFHJPHE_00695	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
GNFHJPHE_00696	1.07e-283	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
GNFHJPHE_00697	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
GNFHJPHE_00698	4.59e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
GNFHJPHE_00699	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GNFHJPHE_00700	2.03e-250	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
GNFHJPHE_00701	4.83e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
GNFHJPHE_00702	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
GNFHJPHE_00703	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
GNFHJPHE_00704	2.27e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
GNFHJPHE_00705	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
GNFHJPHE_00706	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GNFHJPHE_00707	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GNFHJPHE_00708	1.52e-209	-	-	-	S	-	-	-	Tetratricopeptide repeat
GNFHJPHE_00709	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GNFHJPHE_00710	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GNFHJPHE_00711	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GNFHJPHE_00712	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
GNFHJPHE_00713	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
GNFHJPHE_00714	4.93e-20	-	-	-	-	-	-	-	-
GNFHJPHE_00715	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GNFHJPHE_00716	2.94e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GNFHJPHE_00717	2.79e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GNFHJPHE_00718	9.7e-198	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
GNFHJPHE_00719	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
GNFHJPHE_00720	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GNFHJPHE_00721	5.21e-130	-	-	-	-	-	-	-	-
GNFHJPHE_00723	7.21e-164	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GNFHJPHE_00724	3.75e-266	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
GNFHJPHE_00725	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GNFHJPHE_00726	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
GNFHJPHE_00727	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
GNFHJPHE_00728	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
GNFHJPHE_00729	1.98e-180	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
GNFHJPHE_00730	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
GNFHJPHE_00731	9.78e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNFHJPHE_00732	2.91e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
GNFHJPHE_00733	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GNFHJPHE_00734	9.93e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
GNFHJPHE_00735	8.54e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GNFHJPHE_00736	2.35e-38	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_00737	1.29e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GNFHJPHE_00738	5.83e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
GNFHJPHE_00739	8.1e-299	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
GNFHJPHE_00740	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GNFHJPHE_00741	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GNFHJPHE_00742	6.36e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
GNFHJPHE_00743	1.96e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
GNFHJPHE_00744	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
GNFHJPHE_00745	7.97e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
GNFHJPHE_00746	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GNFHJPHE_00747	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GNFHJPHE_00748	3.07e-209	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GNFHJPHE_00749	3.13e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
GNFHJPHE_00750	3.09e-85	-	-	-	-	-	-	-	-
GNFHJPHE_00751	3.23e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GNFHJPHE_00752	3.69e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GNFHJPHE_00753	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
GNFHJPHE_00754	2.2e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GNFHJPHE_00755	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GNFHJPHE_00756	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GNFHJPHE_00757	2.49e-255	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
GNFHJPHE_00759	7.92e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GNFHJPHE_00760	3.36e-77	-	-	-	-	-	-	-	-
GNFHJPHE_00761	1.89e-228	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
GNFHJPHE_00762	2.65e-162	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GNFHJPHE_00763	1.94e-68	-	-	-	-	-	-	-	-
GNFHJPHE_00764	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GNFHJPHE_00765	7.65e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GNFHJPHE_00766	3.1e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
GNFHJPHE_00767	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GNFHJPHE_00768	2.57e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_00769	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GNFHJPHE_00770	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
GNFHJPHE_00771	6.71e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
GNFHJPHE_00772	1.07e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GNFHJPHE_00773	2.07e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
GNFHJPHE_00774	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
GNFHJPHE_00775	4.44e-112	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
GNFHJPHE_00776	1.26e-219	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GNFHJPHE_00777	1.06e-233	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
GNFHJPHE_00778	4.45e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GNFHJPHE_00779	1.66e-77	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
GNFHJPHE_00780	1.48e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GNFHJPHE_00781	2.5e-188	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
GNFHJPHE_00782	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
GNFHJPHE_00783	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
GNFHJPHE_00784	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GNFHJPHE_00785	1.03e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GNFHJPHE_00786	7.19e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GNFHJPHE_00787	1.27e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
GNFHJPHE_00788	2.07e-198	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GNFHJPHE_00789	6.7e-303	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
GNFHJPHE_00790	1.03e-116	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFHJPHE_00791	5.56e-174	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
GNFHJPHE_00792	7.49e-95	-	-	-	-	-	-	-	-
GNFHJPHE_00793	8.08e-89	-	-	-	-	-	-	-	-
GNFHJPHE_00794	1.37e-41	-	-	-	-	-	-	-	-
GNFHJPHE_00797	9.75e-101	-	-	-	K	-	-	-	Peptidase S24-like
GNFHJPHE_00798	3.17e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GNFHJPHE_00806	2.89e-182	-	-	-	L	-	-	-	DnaD domain protein
GNFHJPHE_00807	2e-113	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
GNFHJPHE_00808	2.6e-177	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFHJPHE_00811	2.18e-54	-	-	-	S	-	-	-	HNH endonuclease
GNFHJPHE_00813	4.65e-91	-	-	-	-	-	-	-	-
GNFHJPHE_00814	1.78e-161	-	-	-	-	-	-	-	-
GNFHJPHE_00820	2.79e-102	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
GNFHJPHE_00822	1.96e-06	-	-	-	-	-	-	-	-
GNFHJPHE_00823	5.65e-07	-	-	-	-	-	-	-	-
GNFHJPHE_00825	1.06e-193	-	-	-	L	-	-	-	HNH nucleases
GNFHJPHE_00826	1.62e-100	-	-	-	L	-	-	-	Phage terminase, small subunit
GNFHJPHE_00827	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
GNFHJPHE_00829	2.64e-306	-	-	-	S	-	-	-	Phage portal protein
GNFHJPHE_00830	3.4e-146	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
GNFHJPHE_00831	8.49e-265	-	-	-	S	-	-	-	Phage capsid family
GNFHJPHE_00832	1.15e-89	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
GNFHJPHE_00833	4.51e-54	-	-	-	S	-	-	-	Phage head-tail joining protein
GNFHJPHE_00834	1.52e-81	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
GNFHJPHE_00835	1.4e-100	-	-	-	-	-	-	-	-
GNFHJPHE_00836	3.87e-148	-	-	-	-	-	-	-	-
GNFHJPHE_00838	8.23e-28	-	-	-	-	-	-	-	-
GNFHJPHE_00839	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
GNFHJPHE_00840	1.22e-173	-	-	-	S	-	-	-	Phage tail protein
GNFHJPHE_00841	8.11e-276	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
GNFHJPHE_00843	3.46e-137	-	-	-	M	-	-	-	CotH kinase protein
GNFHJPHE_00844	1.06e-43	-	-	-	-	-	-	-	-
GNFHJPHE_00845	7.81e-71	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
GNFHJPHE_00846	8.74e-241	-	-	-	M	-	-	-	hydrolase, family 25
GNFHJPHE_00847	3.79e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
GNFHJPHE_00848	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GNFHJPHE_00849	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
GNFHJPHE_00850	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
GNFHJPHE_00851	3.1e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
GNFHJPHE_00852	1.93e-210	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
GNFHJPHE_00853	1.23e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GNFHJPHE_00854	9.25e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GNFHJPHE_00855	5.49e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GNFHJPHE_00856	1.49e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GNFHJPHE_00857	2.09e-130	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GNFHJPHE_00858	1.43e-250	-	-	-	S	-	-	-	Helix-turn-helix domain
GNFHJPHE_00859	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
GNFHJPHE_00860	1.04e-69	-	-	-	M	-	-	-	Lysin motif
GNFHJPHE_00861	2.17e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
GNFHJPHE_00862	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
GNFHJPHE_00863	9.51e-317	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
GNFHJPHE_00864	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GNFHJPHE_00865	3.55e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
GNFHJPHE_00866	7.84e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GNFHJPHE_00867	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_00868	2.85e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GNFHJPHE_00869	1.95e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GNFHJPHE_00870	1.23e-142	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
GNFHJPHE_00871	9.07e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
GNFHJPHE_00872	1.04e-215	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
GNFHJPHE_00873	9.54e-140	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
GNFHJPHE_00874	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
GNFHJPHE_00875	1.99e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GNFHJPHE_00876	7.14e-181	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GNFHJPHE_00877	1.85e-205	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
GNFHJPHE_00878	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GNFHJPHE_00879	1.53e-209	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
GNFHJPHE_00880	1.23e-135	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GNFHJPHE_00881	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GNFHJPHE_00882	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GNFHJPHE_00883	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GNFHJPHE_00884	1.02e-103	-	-	-	F	-	-	-	NUDIX domain
GNFHJPHE_00885	7.36e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
GNFHJPHE_00886	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
GNFHJPHE_00887	2.16e-64	-	-	-	-	-	-	-	-
GNFHJPHE_00889	2.87e-112	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
GNFHJPHE_00890	9.07e-80	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
GNFHJPHE_00891	6.23e-35	-	-	-	-	-	-	-	-
GNFHJPHE_00892	2.58e-121	-	-	-	-	-	-	-	-
GNFHJPHE_00893	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
GNFHJPHE_00894	3.24e-231	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
GNFHJPHE_00895	7.71e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
GNFHJPHE_00896	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
GNFHJPHE_00897	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GNFHJPHE_00898	2.78e-62	-	-	-	-	-	-	-	-
GNFHJPHE_00899	1.81e-41	-	-	-	-	-	-	-	-
GNFHJPHE_00900	1.26e-60	-	-	-	-	-	-	-	-
GNFHJPHE_00901	3.91e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
GNFHJPHE_00902	2.15e-217	-	-	-	S	-	-	-	Protein of unknown function DUF262
GNFHJPHE_00903	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
GNFHJPHE_00904	1.89e-115	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
GNFHJPHE_00905	7.47e-29	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
GNFHJPHE_00906	1.27e-224	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFHJPHE_00907	1.83e-51	hsdS	2.1.1.72, 3.1.21.3	-	V	ko:K01154,ko:K03427	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
GNFHJPHE_00908	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
GNFHJPHE_00909	6.1e-277	-	-	-	L	-	-	-	Integrase core domain
GNFHJPHE_00910	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
GNFHJPHE_00911	0.0	-	-	-	L	-	-	-	PLD-like domain
GNFHJPHE_00913	1.75e-228	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
GNFHJPHE_00914	1.32e-231	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GNFHJPHE_00915	8.33e-125	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
GNFHJPHE_00916	1.63e-209	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GNFHJPHE_00917	2.62e-100	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GNFHJPHE_00918	6.06e-145	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
GNFHJPHE_00919	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
GNFHJPHE_00920	8.99e-258	-	-	-	G	-	-	-	Transporter, major facilitator family protein
GNFHJPHE_00921	1.87e-137	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
GNFHJPHE_00922	2.08e-79	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
GNFHJPHE_00923	1.16e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GNFHJPHE_00924	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GNFHJPHE_00925	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
GNFHJPHE_00926	2.84e-42	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
GNFHJPHE_00927	1.56e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
GNFHJPHE_00928	2.36e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
GNFHJPHE_00929	3.04e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GNFHJPHE_00930	1.24e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
GNFHJPHE_00931	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
GNFHJPHE_00932	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GNFHJPHE_00933	6.4e-204	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
GNFHJPHE_00934	7.15e-148	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
GNFHJPHE_00935	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
GNFHJPHE_00936	3.3e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
GNFHJPHE_00937	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
GNFHJPHE_00938	1.09e-191	-	-	-	O	-	-	-	Band 7 protein
GNFHJPHE_00939	8.21e-108	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
GNFHJPHE_00940	3.36e-144	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GNFHJPHE_00941	7.64e-219	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
GNFHJPHE_00942	9.1e-237	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
GNFHJPHE_00943	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
GNFHJPHE_00944	1.48e-168	-	-	-	L	-	-	-	Transposase
GNFHJPHE_00945	2.78e-123	-	-	-	L	-	-	-	Transposase
GNFHJPHE_00946	1.13e-117	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
GNFHJPHE_00947	3.63e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GNFHJPHE_00948	1.13e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
GNFHJPHE_00949	8.5e-218	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
GNFHJPHE_00950	2.86e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
GNFHJPHE_00951	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
GNFHJPHE_00952	1.57e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
GNFHJPHE_00953	7.96e-158	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
GNFHJPHE_00954	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
GNFHJPHE_00955	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
GNFHJPHE_00956	2.01e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GNFHJPHE_00957	4.8e-130	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
GNFHJPHE_00958	3.25e-72	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GNFHJPHE_00959	3.97e-107	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
GNFHJPHE_00960	5.93e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
GNFHJPHE_00961	1.55e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
GNFHJPHE_00962	7.39e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
GNFHJPHE_00963	1.26e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GNFHJPHE_00964	3.24e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GNFHJPHE_00965	5.29e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
GNFHJPHE_00966	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GNFHJPHE_00967	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
GNFHJPHE_00968	1.72e-147	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GNFHJPHE_00969	2.83e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
GNFHJPHE_00970	4.82e-120	-	-	-	-	-	-	-	-
GNFHJPHE_00971	2.4e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GNFHJPHE_00972	4.69e-199	gspA	-	-	M	-	-	-	family 8
GNFHJPHE_00973	5.06e-198	-	-	-	S	-	-	-	Alpha beta hydrolase
GNFHJPHE_00974	8.31e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GNFHJPHE_00975	2.04e-54	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFHJPHE_00983	5.16e-34	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
GNFHJPHE_00985	2.23e-55	-	-	-	-	-	-	-	-
GNFHJPHE_00989	1.43e-43	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
GNFHJPHE_00990	5.28e-46	-	-	-	V	-	-	-	HNH nucleases
GNFHJPHE_00991	4.14e-37	-	-	-	L	-	-	-	Phage terminase, small subunit
GNFHJPHE_00992	3.13e-210	-	-	-	S	-	-	-	Phage Terminase
GNFHJPHE_00993	2.28e-104	-	-	-	S	-	-	-	Phage portal protein
GNFHJPHE_00994	2.33e-122	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
GNFHJPHE_00995	3.5e-09	-	-	-	-	-	-	-	-
GNFHJPHE_00997	1.69e-30	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
GNFHJPHE_00998	5.74e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
GNFHJPHE_01002	1.05e-73	-	-	-	D	-	-	-	domain protein
GNFHJPHE_01003	4.98e-14	-	-	-	S	-	-	-	Phage tail protein
GNFHJPHE_01004	0.000821	-	-	-	M	-	-	-	Prophage endopeptidase tail
GNFHJPHE_01008	8.43e-18	-	-	-	S	-	-	-	COG5546 Small integral membrane protein
GNFHJPHE_01009	3.15e-168	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
GNFHJPHE_01010	0.000354	-	-	-	-	-	-	-	-
GNFHJPHE_01014	4.27e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
GNFHJPHE_01015	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
GNFHJPHE_01016	2.76e-214	yvgN	-	-	C	-	-	-	Aldo keto reductase
GNFHJPHE_01017	1.34e-200	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
GNFHJPHE_01018	7.69e-105	-	-	-	C	-	-	-	Flavodoxin
GNFHJPHE_01019	1.98e-102	-	-	-	S	-	-	-	Cupin domain
GNFHJPHE_01020	3.87e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
GNFHJPHE_01021	1.67e-308	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
GNFHJPHE_01022	1.68e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
GNFHJPHE_01023	1.84e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
GNFHJPHE_01024	4.94e-133	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GNFHJPHE_01025	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
GNFHJPHE_01026	1.23e-184	-	-	-	S	-	-	-	DUF218 domain
GNFHJPHE_01027	2.79e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GNFHJPHE_01028	1.46e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GNFHJPHE_01029	1.73e-70	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GNFHJPHE_01030	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
GNFHJPHE_01031	9.71e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
GNFHJPHE_01032	8.97e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
GNFHJPHE_01033	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GNFHJPHE_01035	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
GNFHJPHE_01036	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GNFHJPHE_01037	1.99e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
GNFHJPHE_01038	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GNFHJPHE_01039	8.32e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
GNFHJPHE_01040	2.26e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
GNFHJPHE_01041	5.93e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
GNFHJPHE_01042	6.43e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GNFHJPHE_01043	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
GNFHJPHE_01044	5.84e-194	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
GNFHJPHE_01045	1.37e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
GNFHJPHE_01047	4.22e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
GNFHJPHE_01048	2.05e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GNFHJPHE_01049	1.77e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GNFHJPHE_01050	4.14e-146	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
GNFHJPHE_01051	6.69e-275	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_01060	4.56e-167	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
GNFHJPHE_01061	3.64e-175	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
GNFHJPHE_01062	2.81e-182	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GNFHJPHE_01063	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
GNFHJPHE_01064	1.55e-95	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GNFHJPHE_01065	1.98e-91	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GNFHJPHE_01066	7.49e-281	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GNFHJPHE_01067	2.76e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
GNFHJPHE_01068	1.29e-192	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
GNFHJPHE_01069	1.99e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GNFHJPHE_01070	1.46e-214	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GNFHJPHE_01071	1.94e-100	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
GNFHJPHE_01072	1.39e-91	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GNFHJPHE_01074	5.67e-257	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFHJPHE_01075	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
GNFHJPHE_01076	5.79e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
GNFHJPHE_01077	2.83e-201	rssA	-	-	S	-	-	-	Phospholipase, patatin family
GNFHJPHE_01078	9.45e-152	-	-	-	L	-	-	-	Integrase
GNFHJPHE_01079	4.63e-197	-	-	-	EG	-	-	-	EamA-like transporter family
GNFHJPHE_01080	1.69e-48	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
GNFHJPHE_01081	1.18e-103	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
GNFHJPHE_01082	3.85e-167	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
GNFHJPHE_01083	7.01e-129	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
GNFHJPHE_01084	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
GNFHJPHE_01085	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GNFHJPHE_01086	3.71e-236	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
GNFHJPHE_01087	9.96e-109	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
GNFHJPHE_01088	3.2e-284	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
GNFHJPHE_01089	2.25e-97	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
GNFHJPHE_01090	2.55e-130	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GNFHJPHE_01091	9.06e-60	-	-	-	-	-	-	-	-
GNFHJPHE_01092	9.18e-243	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
GNFHJPHE_01093	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
GNFHJPHE_01094	1.26e-25	-	-	-	-	-	-	-	-
GNFHJPHE_01095	8.57e-222	-	-	-	-	-	-	-	-
GNFHJPHE_01096	1.49e-182	-	-	-	H	-	-	-	geranyltranstransferase activity
GNFHJPHE_01097	2.14e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
GNFHJPHE_01098	5.33e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
GNFHJPHE_01099	3.65e-81	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
GNFHJPHE_01100	7.28e-101	-	-	-	S	-	-	-	Flavodoxin
GNFHJPHE_01101	9.14e-166	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GNFHJPHE_01102	4.07e-172	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
GNFHJPHE_01103	1.04e-226	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
GNFHJPHE_01104	2.27e-220	-	-	-	-	-	-	-	-
GNFHJPHE_01105	1.89e-96	-	-	-	-	-	-	-	-
GNFHJPHE_01106	6.97e-174	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GNFHJPHE_01107	4.77e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GNFHJPHE_01108	9.07e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GNFHJPHE_01109	1.96e-292	-	-	-	P	-	-	-	Chloride transporter, ClC family
GNFHJPHE_01110	6.64e-51	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
GNFHJPHE_01111	6.23e-93	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
GNFHJPHE_01112	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
GNFHJPHE_01113	1.97e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
GNFHJPHE_01114	9.61e-202	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
GNFHJPHE_01115	6.61e-80	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
GNFHJPHE_01118	7.69e-75	-	-	-	-	-	-	-	-
GNFHJPHE_01119	1.96e-33	-	-	-	-	-	-	-	-
GNFHJPHE_01120	1.83e-194	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
GNFHJPHE_01121	3.94e-158	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GNFHJPHE_01122	1.95e-131	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
GNFHJPHE_01123	5.24e-92	-	-	-	-	-	-	-	-
GNFHJPHE_01124	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GNFHJPHE_01125	7.31e-129	-	-	-	L	-	-	-	nuclease
GNFHJPHE_01126	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
GNFHJPHE_01127	1.12e-265	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GNFHJPHE_01128	1.44e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
GNFHJPHE_01129	0.0	snf	-	-	KL	-	-	-	domain protein
GNFHJPHE_01131	1.59e-49	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
GNFHJPHE_01132	2.23e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
GNFHJPHE_01133	6.02e-291	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_01134	1.41e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_01136	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
GNFHJPHE_01137	4.6e-220	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
GNFHJPHE_01140	2.08e-15	-	-	-	-	-	-	-	-
GNFHJPHE_01141	7.76e-113	doc	-	-	-	ko:K07341	-	ko00000,ko02048	-
GNFHJPHE_01142	1.24e-221	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_01143	2.3e-75	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
GNFHJPHE_01144	1.64e-34	-	-	-	L	ko:K07487	-	ko00000	Transposase
GNFHJPHE_01145	4.82e-25	-	-	-	L	ko:K07487	-	ko00000	Transposase
GNFHJPHE_01146	4.68e-137	-	-	-	S	-	-	-	AAA domain
GNFHJPHE_01147	8.75e-199	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GNFHJPHE_01148	7.77e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GNFHJPHE_01149	3.93e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GNFHJPHE_01150	2.51e-202	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GNFHJPHE_01151	5.51e-119	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
GNFHJPHE_01152	2.55e-114	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
GNFHJPHE_01153	1.93e-97	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GNFHJPHE_01154	1.52e-139	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
GNFHJPHE_01155	4.34e-46	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
GNFHJPHE_01157	1.97e-49	-	-	-	S	-	-	-	Glycosyltransferase like family 2
GNFHJPHE_01158	3.36e-157	-	-	-	M	-	-	-	Glycosyl transferases group 1
GNFHJPHE_01159	8.71e-114	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
GNFHJPHE_01160	1.85e-166	-	-	-	H	-	-	-	Glycosyl transferase family 11
GNFHJPHE_01161	3.19e-119	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
GNFHJPHE_01162	8.85e-79	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
GNFHJPHE_01163	2.74e-96	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
GNFHJPHE_01164	1.2e-130	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
GNFHJPHE_01165	5.26e-159	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
GNFHJPHE_01166	5.21e-196	epsB	-	-	M	-	-	-	biosynthesis protein
GNFHJPHE_01167	3.33e-220	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GNFHJPHE_01168	1.17e-53	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GNFHJPHE_01169	8.89e-79	-	-	-	K	-	-	-	DNA-templated transcription, initiation
GNFHJPHE_01170	2.69e-47	-	-	-	-	-	-	-	-
GNFHJPHE_01171	1.41e-109	-	-	-	-	-	-	-	-
GNFHJPHE_01172	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GNFHJPHE_01173	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
GNFHJPHE_01174	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
GNFHJPHE_01175	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GNFHJPHE_01176	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
GNFHJPHE_01177	5.4e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
GNFHJPHE_01178	5.58e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GNFHJPHE_01179	6.39e-157	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
GNFHJPHE_01182	3.97e-232	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_01183	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GNFHJPHE_01184	2.87e-214	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
GNFHJPHE_01185	1.81e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
GNFHJPHE_01186	8.7e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GNFHJPHE_01187	1.9e-281	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
GNFHJPHE_01188	3.86e-185	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
GNFHJPHE_01189	8.07e-204	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
GNFHJPHE_01190	6.31e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GNFHJPHE_01191	2.23e-236	-	-	-	D	-	-	-	transport
GNFHJPHE_01192	2.46e-13	-	-	-	D	-	-	-	transport
GNFHJPHE_01193	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
GNFHJPHE_01194	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GNFHJPHE_01195	1.11e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
GNFHJPHE_01196	2.54e-101	-	-	-	L	-	-	-	Integrase core domain
GNFHJPHE_01197	3.63e-157	-	-	-	L	-	-	-	Integrase core domain
GNFHJPHE_01198	1.75e-179	-	-	-	L	-	-	-	Bacterial dnaA protein
GNFHJPHE_01199	6.95e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
GNFHJPHE_01200	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GNFHJPHE_01201	3.99e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GNFHJPHE_01202	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GNFHJPHE_01203	1.86e-14	-	-	-	-	-	-	-	-
GNFHJPHE_01204	2.72e-50	-	-	-	-	-	-	-	-
GNFHJPHE_01205	3.08e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
GNFHJPHE_01206	8.66e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
GNFHJPHE_01207	3.99e-299	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
GNFHJPHE_01208	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_01209	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GNFHJPHE_01210	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
GNFHJPHE_01211	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
GNFHJPHE_01212	1.79e-117	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GNFHJPHE_01213	5.32e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
GNFHJPHE_01214	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
GNFHJPHE_01215	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GNFHJPHE_01216	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GNFHJPHE_01217	3.31e-257	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GNFHJPHE_01218	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
GNFHJPHE_01219	6.38e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GNFHJPHE_01220	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GNFHJPHE_01221	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GNFHJPHE_01222	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GNFHJPHE_01223	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
GNFHJPHE_01224	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
GNFHJPHE_01225	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
GNFHJPHE_01226	1.57e-155	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
GNFHJPHE_01227	4.49e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
GNFHJPHE_01228	4.7e-206	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GNFHJPHE_01229	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
GNFHJPHE_01230	3.36e-165	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
GNFHJPHE_01231	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GNFHJPHE_01232	3.92e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GNFHJPHE_01233	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GNFHJPHE_01234	8.76e-264	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GNFHJPHE_01235	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GNFHJPHE_01236	3.59e-147	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
GNFHJPHE_01237	2.48e-69	-	-	-	-	-	-	-	-
GNFHJPHE_01238	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
GNFHJPHE_01239	8.81e-98	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
GNFHJPHE_01240	2.3e-190	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
GNFHJPHE_01241	1.06e-199	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GNFHJPHE_01242	1.15e-57	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GNFHJPHE_01243	4.6e-279	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GNFHJPHE_01244	1.88e-191	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GNFHJPHE_01245	1.84e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GNFHJPHE_01246	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
GNFHJPHE_01247	1.22e-147	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
GNFHJPHE_01248	1.23e-255	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GNFHJPHE_01249	7.44e-168	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GNFHJPHE_01250	5.93e-60	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
GNFHJPHE_01251	8.44e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
GNFHJPHE_01252	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
GNFHJPHE_01253	9.45e-145	-	-	-	K	-	-	-	Transcriptional regulator
GNFHJPHE_01256	3.19e-111	-	-	-	S	-	-	-	Protein conserved in bacteria
GNFHJPHE_01257	1.67e-229	-	-	-	-	-	-	-	-
GNFHJPHE_01258	8.07e-202	-	-	-	-	-	-	-	-
GNFHJPHE_01259	1.27e-66	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GNFHJPHE_01260	2.72e-129	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GNFHJPHE_01261	1.28e-18	-	-	-	-	-	-	-	-
GNFHJPHE_01262	5.49e-52	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GNFHJPHE_01263	5.74e-40	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GNFHJPHE_01264	6.01e-120	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GNFHJPHE_01265	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GNFHJPHE_01266	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
GNFHJPHE_01267	1.96e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GNFHJPHE_01268	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
GNFHJPHE_01269	5.18e-86	yqhL	-	-	P	-	-	-	Rhodanese-like protein
GNFHJPHE_01270	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
GNFHJPHE_01271	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
GNFHJPHE_01272	1.76e-26	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
GNFHJPHE_01273	7.32e-99	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
GNFHJPHE_01274	8e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GNFHJPHE_01275	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GNFHJPHE_01276	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GNFHJPHE_01277	0.0	-	-	-	S	-	-	-	membrane
GNFHJPHE_01278	2.13e-88	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
GNFHJPHE_01279	3.07e-303	-	-	-	L	-	-	-	Transposase
GNFHJPHE_01280	3.52e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GNFHJPHE_01281	2.8e-150	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
GNFHJPHE_01282	3.29e-146	-	-	-	M	-	-	-	PFAM NLP P60 protein
GNFHJPHE_01283	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GNFHJPHE_01284	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GNFHJPHE_01285	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GNFHJPHE_01286	7.57e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GNFHJPHE_01287	3.16e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GNFHJPHE_01288	2.36e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
GNFHJPHE_01289	2.25e-214	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GNFHJPHE_01290	3.73e-90	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
GNFHJPHE_01291	1.68e-294	-	-	-	V	-	-	-	MatE
GNFHJPHE_01292	0.0	potE	-	-	E	-	-	-	Amino Acid
GNFHJPHE_01293	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GNFHJPHE_01294	1.38e-155	csrR	-	-	K	-	-	-	response regulator
GNFHJPHE_01295	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
GNFHJPHE_01296	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
GNFHJPHE_01297	1.72e-267	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
GNFHJPHE_01298	3.54e-176	yqeM	-	-	Q	-	-	-	Methyltransferase
GNFHJPHE_01299	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GNFHJPHE_01300	6.69e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
GNFHJPHE_01301	3.87e-155	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GNFHJPHE_01302	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
GNFHJPHE_01303	7.72e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
GNFHJPHE_01304	7.78e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
GNFHJPHE_01305	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GNFHJPHE_01306	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
GNFHJPHE_01307	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GNFHJPHE_01308	8.6e-222	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
GNFHJPHE_01309	5.46e-298	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
GNFHJPHE_01310	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GNFHJPHE_01311	2.69e-125	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GNFHJPHE_01312	1.25e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GNFHJPHE_01313	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GNFHJPHE_01314	8.88e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
GNFHJPHE_01315	1.22e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
GNFHJPHE_01316	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
GNFHJPHE_01317	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
GNFHJPHE_01318	5.7e-153	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GNFHJPHE_01319	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
GNFHJPHE_01320	5.37e-74	-	-	-	S	-	-	-	Small secreted protein
GNFHJPHE_01321	1.59e-14	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
GNFHJPHE_01322	1.57e-73	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
GNFHJPHE_01323	6.22e-40	-	-	-	S	-	-	-	YSIRK type signal peptide
GNFHJPHE_01324	4.36e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GNFHJPHE_01325	3.68e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
GNFHJPHE_01326	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01327	4.99e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
GNFHJPHE_01329	4.08e-176	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GNFHJPHE_01330	0.0	yhaN	-	-	L	-	-	-	AAA domain
GNFHJPHE_01331	1.07e-281	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
GNFHJPHE_01332	6.93e-64	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
GNFHJPHE_01333	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
GNFHJPHE_01334	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
GNFHJPHE_01335	6.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GNFHJPHE_01336	8.18e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GNFHJPHE_01338	2.47e-53	-	-	-	-	-	-	-	-
GNFHJPHE_01339	2.67e-60	-	-	-	-	-	-	-	-
GNFHJPHE_01340	1.05e-273	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
GNFHJPHE_01341	2.01e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
GNFHJPHE_01342	2.61e-281	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
GNFHJPHE_01343	1.94e-135	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
GNFHJPHE_01344	1.25e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
GNFHJPHE_01345	8.28e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GNFHJPHE_01346	4.1e-87	-	-	-	-	-	-	-	-
GNFHJPHE_01347	2.69e-180	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFHJPHE_01348	2.23e-11	-	-	-	K	-	-	-	transcriptional
GNFHJPHE_01349	1.99e-20	-	-	-	-	-	-	-	-
GNFHJPHE_01350	7.33e-57	-	-	-	K	-	-	-	COG3617 Prophage antirepressor
GNFHJPHE_01351	5.44e-07	-	-	-	S	-	-	-	Helix-turn-helix domain
GNFHJPHE_01357	1.35e-12	-	-	-	L	-	-	-	DnaD domain protein
GNFHJPHE_01359	2.86e-79	-	-	-	-	-	-	-	-
GNFHJPHE_01361	7.93e-07	-	-	-	-	-	-	-	-
GNFHJPHE_01363	9.17e-59	-	-	-	-	-	-	-	-
GNFHJPHE_01364	8.99e-141	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GNFHJPHE_01365	1.78e-42	-	-	-	-	-	-	-	-
GNFHJPHE_01366	6.94e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GNFHJPHE_01367	1.25e-238	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
GNFHJPHE_01368	3.6e-145	-	-	-	-	-	-	-	-
GNFHJPHE_01369	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
GNFHJPHE_01370	7.77e-223	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GNFHJPHE_01371	2.18e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
GNFHJPHE_01372	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
GNFHJPHE_01373	2.05e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GNFHJPHE_01374	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
GNFHJPHE_01375	1.77e-56	-	-	-	-	-	-	-	-
GNFHJPHE_01376	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
GNFHJPHE_01377	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GNFHJPHE_01378	1.28e-120	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
GNFHJPHE_01379	0.0	-	-	-	EGP	-	-	-	Major Facilitator
GNFHJPHE_01380	1.46e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
GNFHJPHE_01381	2.01e-302	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GNFHJPHE_01382	5.83e-135	-	-	-	V	-	-	-	VanZ like family
GNFHJPHE_01383	7.03e-33	-	-	-	-	-	-	-	-
GNFHJPHE_01384	2.91e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
GNFHJPHE_01385	1.08e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
GNFHJPHE_01386	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
GNFHJPHE_01387	3.81e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GNFHJPHE_01388	3.69e-196	yeaE	-	-	S	-	-	-	Aldo keto
GNFHJPHE_01389	3.25e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
GNFHJPHE_01390	9.02e-295	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GNFHJPHE_01391	5.48e-188	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
GNFHJPHE_01392	4.17e-134	-	-	-	M	-	-	-	LysM domain protein
GNFHJPHE_01393	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
GNFHJPHE_01394	2.14e-146	-	-	-	M	-	-	-	LysM domain protein
GNFHJPHE_01395	2.05e-200	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
GNFHJPHE_01396	1.61e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GNFHJPHE_01397	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
GNFHJPHE_01398	2.89e-309	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
GNFHJPHE_01399	2.37e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GNFHJPHE_01411	5.67e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
GNFHJPHE_01412	9.33e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GNFHJPHE_01413	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
GNFHJPHE_01414	2.1e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
GNFHJPHE_01415	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GNFHJPHE_01416	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
GNFHJPHE_01417	5.62e-37	-	-	-	-	-	-	-	-
GNFHJPHE_01418	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
GNFHJPHE_01419	1.82e-129	-	-	-	S	-	-	-	Pfam:DUF3816
GNFHJPHE_01420	3.86e-182	-	-	-	G	-	-	-	MucBP domain
GNFHJPHE_01421	7.04e-149	-	-	-	-	-	-	-	-
GNFHJPHE_01422	5.04e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01423	1.19e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
GNFHJPHE_01424	1.51e-57	-	-	-	V	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
GNFHJPHE_01425	6.47e-66	-	-	-	M	-	-	-	Peptidase_C39 like family
GNFHJPHE_01426	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GNFHJPHE_01427	2.39e-301	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GNFHJPHE_01428	2.39e-189	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_01429	4.59e-67	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_01430	2.68e-28	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_01431	5.35e-200	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
GNFHJPHE_01432	8.39e-229	yueF	-	-	S	-	-	-	AI-2E family transporter
GNFHJPHE_01433	1.99e-81	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	dextransucrase activity
GNFHJPHE_01434	2.78e-51	-	-	-	S	-	-	-	Acyltransferase family
GNFHJPHE_01435	1.39e-35	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
GNFHJPHE_01437	4.58e-88	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
GNFHJPHE_01438	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
GNFHJPHE_01439	6.1e-277	-	-	-	L	-	-	-	Integrase core domain
GNFHJPHE_01440	6.33e-135	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GNFHJPHE_01441	3.73e-171	-	-	-	M	-	-	-	Glycosyltransferase like family 2
GNFHJPHE_01442	1.75e-40	-	-	-	-	-	-	-	-
GNFHJPHE_01443	2.72e-200	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
GNFHJPHE_01444	5.11e-187	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
GNFHJPHE_01445	1.6e-80	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
GNFHJPHE_01446	1.85e-93	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_01447	8.56e-236	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
GNFHJPHE_01448	3.5e-249	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
GNFHJPHE_01449	1.8e-247	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
GNFHJPHE_01450	1.18e-253	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
GNFHJPHE_01451	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
GNFHJPHE_01452	1.43e-134	-	-	-	M	-	-	-	biosynthesis protein
GNFHJPHE_01453	6.35e-276	cps3F	-	-	-	-	-	-	-
GNFHJPHE_01454	1.88e-273	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
GNFHJPHE_01455	1.91e-151	-	-	-	M	-	-	-	Bacterial sugar transferase
GNFHJPHE_01456	4.08e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
GNFHJPHE_01457	7.79e-189	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
GNFHJPHE_01458	2.1e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
GNFHJPHE_01459	2.53e-42	-	-	-	-	-	-	-	-
GNFHJPHE_01460	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
GNFHJPHE_01461	6.86e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
GNFHJPHE_01462	0.0	potE	-	-	E	-	-	-	Amino Acid
GNFHJPHE_01463	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
GNFHJPHE_01464	1.97e-280	arcT	-	-	E	-	-	-	Aminotransferase
GNFHJPHE_01465	4.96e-216	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
GNFHJPHE_01466	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
GNFHJPHE_01467	2.45e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
GNFHJPHE_01468	7.03e-23	-	-	-	-	-	-	-	-
GNFHJPHE_01469	6.19e-46	-	-	-	-	-	-	-	-
GNFHJPHE_01470	4.92e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GNFHJPHE_01472	6.37e-296	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
GNFHJPHE_01473	6.24e-244	mocA	-	-	S	-	-	-	Oxidoreductase
GNFHJPHE_01474	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
GNFHJPHE_01475	3.07e-137	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
GNFHJPHE_01476	1.15e-207	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
GNFHJPHE_01477	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
GNFHJPHE_01478	1.36e-248	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
GNFHJPHE_01479	4.36e-103	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
GNFHJPHE_01480	3.59e-150	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
GNFHJPHE_01481	6.99e-90	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_01482	2.35e-84	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_01483	3.86e-95	-	-	-	P	-	-	-	Major Facilitator Superfamily
GNFHJPHE_01485	1.46e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
GNFHJPHE_01486	2.03e-100	-	-	-	K	-	-	-	LytTr DNA-binding domain
GNFHJPHE_01487	2.62e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
GNFHJPHE_01488	1e-217	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
GNFHJPHE_01489	1.45e-97	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
GNFHJPHE_01490	2.94e-156	pnb	-	-	C	-	-	-	nitroreductase
GNFHJPHE_01491	4.18e-119	-	-	-	-	-	-	-	-
GNFHJPHE_01492	2.38e-109	yvbK	-	-	K	-	-	-	GNAT family
GNFHJPHE_01493	2.5e-313	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
GNFHJPHE_01494	1.16e-265	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
GNFHJPHE_01495	0.0	-	-	-	L	-	-	-	Transposase
GNFHJPHE_01496	9.18e-242	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_01497	1.01e-165	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
GNFHJPHE_01498	3.31e-135	pncA	-	-	Q	-	-	-	Isochorismatase family
GNFHJPHE_01499	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GNFHJPHE_01500	1.26e-163	-	-	-	F	-	-	-	NUDIX domain
GNFHJPHE_01501	2.99e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GNFHJPHE_01502	4.03e-202	-	-	-	S	-	-	-	Phage capsid family
GNFHJPHE_01503	1.21e-54	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
GNFHJPHE_01504	8.31e-73	-	-	-	S	-	-	-	Phage head-tail joining protein
GNFHJPHE_01505	7.67e-74	-	-	-	S	-	-	-	Bacteriophage holin family
GNFHJPHE_01506	7.96e-27	-	-	-	-	-	-	-	-
GNFHJPHE_01507	4.38e-86	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
GNFHJPHE_01508	2.05e-105	-	-	-	L	-	-	-	Recombinase
GNFHJPHE_01509	2.52e-75	-	-	-	L	ko:K06400	-	ko00000	Recombinase
GNFHJPHE_01510	1.13e-70	-	-	-	L	ko:K06400	-	ko00000	Recombinase
GNFHJPHE_01511	1.96e-30	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
GNFHJPHE_01512	6.94e-80	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
GNFHJPHE_01513	3.49e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
GNFHJPHE_01514	4.13e-147	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
GNFHJPHE_01515	1.23e-121	dpsB	-	-	P	-	-	-	Belongs to the Dps family
GNFHJPHE_01516	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
GNFHJPHE_01517	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
GNFHJPHE_01518	2.48e-178	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GNFHJPHE_01519	1.21e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
GNFHJPHE_01521	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
GNFHJPHE_01522	3.96e-61	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
GNFHJPHE_01523	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GNFHJPHE_01524	2.23e-236	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
GNFHJPHE_01525	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GNFHJPHE_01526	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GNFHJPHE_01527	9.59e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GNFHJPHE_01528	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
GNFHJPHE_01529	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GNFHJPHE_01530	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
GNFHJPHE_01531	4.55e-267	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GNFHJPHE_01532	2.75e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GNFHJPHE_01533	5.09e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
GNFHJPHE_01534	2.58e-179	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
GNFHJPHE_01535	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
GNFHJPHE_01536	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GNFHJPHE_01537	1.75e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GNFHJPHE_01538	2.89e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GNFHJPHE_01539	3.8e-194	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GNFHJPHE_01540	9.88e-177	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GNFHJPHE_01541	1.15e-82	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
GNFHJPHE_01542	1.27e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GNFHJPHE_01543	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GNFHJPHE_01544	2.19e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GNFHJPHE_01545	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
GNFHJPHE_01546	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GNFHJPHE_01547	1.51e-159	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GNFHJPHE_01548	8.24e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GNFHJPHE_01549	7.07e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GNFHJPHE_01550	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
GNFHJPHE_01551	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GNFHJPHE_01552	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GNFHJPHE_01553	6.12e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GNFHJPHE_01554	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GNFHJPHE_01555	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GNFHJPHE_01556	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GNFHJPHE_01557	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GNFHJPHE_01558	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GNFHJPHE_01559	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GNFHJPHE_01560	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
GNFHJPHE_01561	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GNFHJPHE_01562	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GNFHJPHE_01563	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GNFHJPHE_01564	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GNFHJPHE_01565	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GNFHJPHE_01566	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GNFHJPHE_01567	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
GNFHJPHE_01568	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GNFHJPHE_01569	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
GNFHJPHE_01570	3.86e-299	isp	-	-	L	-	-	-	Transposase
GNFHJPHE_01571	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GNFHJPHE_01572	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GNFHJPHE_01573	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GNFHJPHE_01574	8.83e-141	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
GNFHJPHE_01575	1.29e-260	-	-	-	-	-	-	-	-
GNFHJPHE_01576	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GNFHJPHE_01577	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GNFHJPHE_01578	8.51e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GNFHJPHE_01579	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GNFHJPHE_01580	1.62e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
GNFHJPHE_01581	2.56e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
GNFHJPHE_01582	1.13e-193	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
GNFHJPHE_01583	3.64e-147	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_01589	3.04e-147	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
GNFHJPHE_01590	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
GNFHJPHE_01591	1.69e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GNFHJPHE_01592	7.68e-151	-	-	-	I	-	-	-	phosphatase
GNFHJPHE_01593	8.68e-106	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
GNFHJPHE_01594	5.75e-164	-	-	-	S	-	-	-	Putative threonine/serine exporter
GNFHJPHE_01595	2.54e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
GNFHJPHE_01596	1.83e-158	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
GNFHJPHE_01597	1.11e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
GNFHJPHE_01598	1.22e-150	-	-	-	S	-	-	-	membrane
GNFHJPHE_01599	3.18e-140	-	-	-	S	-	-	-	VIT family
GNFHJPHE_01600	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
GNFHJPHE_01601	1.38e-95	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01602	6.98e-58	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01603	3.85e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GNFHJPHE_01604	5.24e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GNFHJPHE_01605	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GNFHJPHE_01606	8.11e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GNFHJPHE_01607	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GNFHJPHE_01608	8.46e-77	-	-	-	-	-	-	-	-
GNFHJPHE_01609	5.98e-95	-	-	-	K	-	-	-	MerR HTH family regulatory protein
GNFHJPHE_01610	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
GNFHJPHE_01611	4.39e-159	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
GNFHJPHE_01612	2.64e-209	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GNFHJPHE_01614	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GNFHJPHE_01615	7.62e-132	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
GNFHJPHE_01616	3.06e-238	-	-	-	I	-	-	-	Alpha beta
GNFHJPHE_01617	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
GNFHJPHE_01618	2.6e-150	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
GNFHJPHE_01619	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
GNFHJPHE_01620	6.91e-203	-	-	-	K	-	-	-	LysR family
GNFHJPHE_01621	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
GNFHJPHE_01622	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
GNFHJPHE_01623	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GNFHJPHE_01624	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
GNFHJPHE_01625	2.9e-202	mleR	-	-	K	-	-	-	LysR family
GNFHJPHE_01626	1.12e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GNFHJPHE_01627	3.17e-262	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
GNFHJPHE_01628	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
GNFHJPHE_01629	4.49e-215	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_01630	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
GNFHJPHE_01631	1.19e-31	-	-	-	-	-	-	-	-
GNFHJPHE_01632	6.09e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
GNFHJPHE_01633	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GNFHJPHE_01634	4.24e-94	-	-	-	-	-	-	-	-
GNFHJPHE_01635	3.8e-292	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GNFHJPHE_01636	1.67e-179	-	-	-	V	-	-	-	Beta-lactamase enzyme family
GNFHJPHE_01637	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
GNFHJPHE_01638	1.28e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
GNFHJPHE_01639	0.0	arcT	-	-	E	-	-	-	Dipeptidase
GNFHJPHE_01640	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GNFHJPHE_01641	1.56e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
GNFHJPHE_01642	3.23e-213	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
GNFHJPHE_01643	1.45e-171	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GNFHJPHE_01644	4.8e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
GNFHJPHE_01645	8.7e-123	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
GNFHJPHE_01646	1.04e-213	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GNFHJPHE_01647	1.1e-227	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
GNFHJPHE_01648	6.31e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
GNFHJPHE_01649	1.12e-112	-	-	-	Q	-	-	-	Methyltransferase
GNFHJPHE_01650	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
GNFHJPHE_01651	1.12e-303	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
GNFHJPHE_01652	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
GNFHJPHE_01653	1.33e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
GNFHJPHE_01654	1.77e-286	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
GNFHJPHE_01655	3.27e-311	-	-	-	M	-	-	-	Glycosyl transferase
GNFHJPHE_01657	1.63e-197	-	-	-	-	-	-	-	-
GNFHJPHE_01658	6.09e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
GNFHJPHE_01659	9.02e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GNFHJPHE_01660	2.7e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
GNFHJPHE_01661	4.58e-194	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
GNFHJPHE_01662	4.02e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
GNFHJPHE_01663	3.98e-168	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
GNFHJPHE_01664	1.51e-21	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GNFHJPHE_01665	6.97e-240	-	-	-	-	-	-	-	-
GNFHJPHE_01666	5.26e-123	-	-	-	K	-	-	-	acetyltransferase
GNFHJPHE_01667	1.42e-85	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
GNFHJPHE_01668	1.56e-41	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
GNFHJPHE_01669	1.71e-89	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
GNFHJPHE_01670	8.83e-77	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GNFHJPHE_01671	3.07e-303	-	-	-	L	-	-	-	Transposase
GNFHJPHE_01672	1.07e-239	-	-	-	-	-	-	-	-
GNFHJPHE_01673	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GNFHJPHE_01674	1.26e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
GNFHJPHE_01675	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GNFHJPHE_01676	0.0	-	-	-	M	-	-	-	Leucine-rich repeat (LRR) protein
GNFHJPHE_01678	2.15e-202	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GNFHJPHE_01679	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GNFHJPHE_01680	7.13e-158	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
GNFHJPHE_01681	2.15e-39	-	-	-	L	-	-	-	Helix-turn-helix domain
GNFHJPHE_01682	8.91e-293	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_01683	1.41e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_01684	5.75e-52	-	-	-	S	-	-	-	Cytochrome B5
GNFHJPHE_01687	3.7e-19	-	-	-	-	-	-	-	-
GNFHJPHE_01688	8.11e-263	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
GNFHJPHE_01689	1.24e-49	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
GNFHJPHE_01690	1.47e-43	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
GNFHJPHE_01691	4.67e-72	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
GNFHJPHE_01692	1.28e-37	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
GNFHJPHE_01693	1.91e-103	-	-	-	-	-	-	-	-
GNFHJPHE_01694	3.49e-158	-	-	-	M	-	-	-	Lysin motif
GNFHJPHE_01695	1.45e-287	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_01696	1.41e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_01697	8.17e-250	-	-	-	EGP	-	-	-	Major Facilitator
GNFHJPHE_01698	1.59e-49	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
GNFHJPHE_01699	3.4e-66	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
GNFHJPHE_01700	3.65e-114	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
GNFHJPHE_01701	9.88e-205	-	-	-	J	-	-	-	Methyltransferase
GNFHJPHE_01702	4.24e-288	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
GNFHJPHE_01703	1.21e-44	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFHJPHE_01704	1.52e-43	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GNFHJPHE_01706	4.94e-133	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GNFHJPHE_01707	3.1e-266	ebh	-	-	D	-	-	-	interspecies interaction between organisms
GNFHJPHE_01708	9.88e-199	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_01709	4.78e-26	-	-	-	-	-	-	-	-
GNFHJPHE_01710	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
GNFHJPHE_01712	2.81e-278	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
GNFHJPHE_01713	8.32e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
GNFHJPHE_01714	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GNFHJPHE_01715	5.07e-202	-	-	-	EG	-	-	-	EamA-like transporter family
GNFHJPHE_01716	4.41e-49	-	-	-	Q	-	-	-	pyridine nucleotide-disulphide oxidoreductase
GNFHJPHE_01717	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
GNFHJPHE_01718	6.35e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
GNFHJPHE_01719	6.69e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
GNFHJPHE_01720	2.8e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GNFHJPHE_01721	5.25e-45	-	-	-	S	-	-	-	Transglycosylase associated protein
GNFHJPHE_01722	6.47e-10	-	-	-	S	-	-	-	CsbD-like
GNFHJPHE_01723	1.24e-229	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNFHJPHE_01724	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
GNFHJPHE_01725	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
GNFHJPHE_01726	6.09e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
GNFHJPHE_01727	5.43e-192	-	-	-	-	-	-	-	-
GNFHJPHE_01728	1.15e-28	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
GNFHJPHE_01729	8.27e-105	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
GNFHJPHE_01730	1.8e-130	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
GNFHJPHE_01731	1.78e-97	-	-	-	F	-	-	-	Nudix hydrolase
GNFHJPHE_01732	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
GNFHJPHE_01733	1.69e-296	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
GNFHJPHE_01734	2.36e-82	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_01735	4.73e-78	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_01736	2.17e-79	-	-	-	-	-	-	-	-
GNFHJPHE_01737	1.52e-66	-	-	-	-	-	-	-	-
GNFHJPHE_01738	1.89e-41	-	-	-	-	-	-	-	-
GNFHJPHE_01739	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GNFHJPHE_01740	2.56e-182	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GNFHJPHE_01741	1.01e-186	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GNFHJPHE_01742	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GNFHJPHE_01743	8.2e-289	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_01744	5.74e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_01745	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GNFHJPHE_01746	6.09e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GNFHJPHE_01747	5.13e-59	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GNFHJPHE_01748	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GNFHJPHE_01749	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
GNFHJPHE_01750	4.48e-63	yagE	-	-	E	-	-	-	amino acid
GNFHJPHE_01751	7.74e-223	yagE	-	-	E	-	-	-	amino acid
GNFHJPHE_01752	2.14e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
GNFHJPHE_01753	3.06e-121	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GNFHJPHE_01754	1.69e-44	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GNFHJPHE_01755	2.41e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
GNFHJPHE_01756	6.65e-234	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
GNFHJPHE_01757	8.2e-289	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_01758	5.74e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_01759	5.68e-12	-	-	-	IQ	-	-	-	KR domain
GNFHJPHE_01760	7.72e-145	-	-	-	IQ	-	-	-	KR domain
GNFHJPHE_01761	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GNFHJPHE_01762	5.18e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
GNFHJPHE_01763	9.45e-314	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01764	1.14e-144	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
GNFHJPHE_01765	6.5e-71	-	-	-	-	-	-	-	-
GNFHJPHE_01766	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GNFHJPHE_01767	7.42e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
GNFHJPHE_01768	1.59e-219	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
GNFHJPHE_01769	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
GNFHJPHE_01770	1.92e-204	-	-	-	-	-	-	-	-
GNFHJPHE_01771	9.72e-167	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNFHJPHE_01772	6.43e-214	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GNFHJPHE_01773	1.4e-109	-	-	-	K	-	-	-	FCD
GNFHJPHE_01774	2.5e-173	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
GNFHJPHE_01775	4.02e-27	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
GNFHJPHE_01776	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
GNFHJPHE_01777	4.58e-269	-	-	-	EGP	-	-	-	Major Facilitator
GNFHJPHE_01778	2.16e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GNFHJPHE_01779	4.72e-151	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
GNFHJPHE_01780	2.31e-11	-	-	-	-	-	-	-	-
GNFHJPHE_01781	1.78e-83	-	-	-	-	-	-	-	-
GNFHJPHE_01782	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
GNFHJPHE_01783	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
GNFHJPHE_01784	0.0	fusA1	-	-	J	-	-	-	elongation factor G
GNFHJPHE_01785	4.21e-211	-	-	-	GK	-	-	-	ROK family
GNFHJPHE_01786	7.66e-308	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GNFHJPHE_01787	4.83e-175	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
GNFHJPHE_01788	1.1e-296	-	-	-	E	-	-	-	amino acid
GNFHJPHE_01789	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
GNFHJPHE_01790	3.48e-161	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
GNFHJPHE_01791	7.53e-110	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GNFHJPHE_01792	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GNFHJPHE_01793	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
GNFHJPHE_01794	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
GNFHJPHE_01795	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01796	1.16e-23	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
GNFHJPHE_01797	1.86e-227	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNFHJPHE_01798	2.23e-13	-	-	-	S	-	-	-	PFAM Archaeal ATPase
GNFHJPHE_01799	2.35e-102	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
GNFHJPHE_01800	4.28e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
GNFHJPHE_01801	1.94e-22	-	-	-	EG	-	-	-	PFAM EamA-like transporter family
GNFHJPHE_01802	1.78e-23	-	-	-	EG	-	-	-	EamA-like transporter family
GNFHJPHE_01803	3.2e-185	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
GNFHJPHE_01804	7.73e-92	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
GNFHJPHE_01805	4.47e-95	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
GNFHJPHE_01806	2.56e-152	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GNFHJPHE_01807	1.41e-98	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
GNFHJPHE_01808	3.91e-305	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
GNFHJPHE_01809	2.77e-223	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
GNFHJPHE_01810	2.67e-173	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GNFHJPHE_01811	1.34e-245	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GNFHJPHE_01812	5.47e-75	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
GNFHJPHE_01813	2.28e-301	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
GNFHJPHE_01814	2.92e-154	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
GNFHJPHE_01815	1.32e-131	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
GNFHJPHE_01816	8.36e-59	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GNFHJPHE_01817	1.11e-157	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GNFHJPHE_01818	5.52e-117	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
GNFHJPHE_01819	3.42e-139	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
GNFHJPHE_01820	2.42e-223	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
GNFHJPHE_01821	1.51e-125	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
GNFHJPHE_01822	2.29e-165	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
GNFHJPHE_01823	3.13e-181	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
GNFHJPHE_01824	5.75e-165	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
GNFHJPHE_01825	7.05e-100	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
GNFHJPHE_01826	6.19e-102	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
GNFHJPHE_01827	1.39e-244	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GNFHJPHE_01828	5.48e-139	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
GNFHJPHE_01829	4.35e-186	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GNFHJPHE_01830	6.68e-258	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
GNFHJPHE_01831	1.63e-214	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
GNFHJPHE_01832	1.72e-102	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
GNFHJPHE_01833	4.92e-147	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
GNFHJPHE_01834	6.45e-95	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
GNFHJPHE_01835	1.44e-90	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
GNFHJPHE_01836	3.45e-87	-	-	-	P	-	-	-	Cadmium resistance transporter
GNFHJPHE_01837	3.03e-96	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
GNFHJPHE_01838	1.08e-147	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
GNFHJPHE_01839	5.3e-71	-	-	-	E	ko:K04031	-	ko00000	BMC
GNFHJPHE_01840	2.06e-277	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GNFHJPHE_01841	2.5e-258	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
GNFHJPHE_01842	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
GNFHJPHE_01843	1.62e-101	pduO	-	-	S	-	-	-	Haem-degrading
GNFHJPHE_01844	3.33e-133	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
GNFHJPHE_01845	5.63e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
GNFHJPHE_01846	6.17e-104	-	-	-	S	-	-	-	Putative propanediol utilisation
GNFHJPHE_01847	1.98e-148	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
GNFHJPHE_01848	3.65e-53	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
GNFHJPHE_01849	2.67e-74	-	-	-	CQ	-	-	-	BMC
GNFHJPHE_01850	4.57e-60	pduH	-	-	S	-	-	-	Dehydratase medium subunit
GNFHJPHE_01851	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
GNFHJPHE_01852	8.85e-97	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
GNFHJPHE_01853	5e-162	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
GNFHJPHE_01854	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
GNFHJPHE_01855	3.41e-170	pduB	-	-	E	-	-	-	BMC
GNFHJPHE_01856	2.33e-50	-	-	-	CQ	-	-	-	BMC
GNFHJPHE_01857	1.69e-202	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GNFHJPHE_01858	4.02e-177	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
GNFHJPHE_01859	9.82e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GNFHJPHE_01860	8.24e-205	-	-	-	-	-	-	-	-
GNFHJPHE_01861	8.07e-199	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
GNFHJPHE_01862	4.09e-235	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
GNFHJPHE_01863	3.53e-169	XK27_07210	-	-	S	-	-	-	B3 4 domain
GNFHJPHE_01864	5.75e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
GNFHJPHE_01865	5.04e-116	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
GNFHJPHE_01866	9.43e-116	-	-	-	GM	-	-	-	epimerase
GNFHJPHE_01867	1.14e-197	-	-	-	V	-	-	-	(ABC) transporter
GNFHJPHE_01868	6.23e-303	yhdP	-	-	S	-	-	-	Transporter associated domain
GNFHJPHE_01869	3.16e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
GNFHJPHE_01870	4.3e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
GNFHJPHE_01871	7.93e-242	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
GNFHJPHE_01872	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GNFHJPHE_01873	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GNFHJPHE_01874	4.67e-39	-	-	-	-	-	-	-	-
GNFHJPHE_01875	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GNFHJPHE_01876	2.56e-292	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GNFHJPHE_01877	1.41e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
GNFHJPHE_01878	1.14e-49	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
GNFHJPHE_01879	1.06e-55	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
GNFHJPHE_01880	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
GNFHJPHE_01881	5.44e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
GNFHJPHE_01882	5.8e-291	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GNFHJPHE_01883	2.6e-141	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
GNFHJPHE_01884	6.19e-115	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GNFHJPHE_01885	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GNFHJPHE_01886	1.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
GNFHJPHE_01887	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
GNFHJPHE_01888	4.92e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GNFHJPHE_01889	1.89e-227	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
GNFHJPHE_01890	4.49e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GNFHJPHE_01891	9.21e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
GNFHJPHE_01892	1.21e-48	-	-	-	-	-	-	-	-
GNFHJPHE_01893	1.76e-68	-	-	-	-	-	-	-	-
GNFHJPHE_01894	4.14e-257	-	-	-	-	-	-	-	-
GNFHJPHE_01895	1.59e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GNFHJPHE_01896	2.68e-173	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
GNFHJPHE_01897	3.44e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
GNFHJPHE_01898	2.51e-160	XK27_10500	-	-	K	-	-	-	response regulator
GNFHJPHE_01899	1.02e-231	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
GNFHJPHE_01900	1.67e-172	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01901	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
GNFHJPHE_01902	9.5e-200	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
GNFHJPHE_01903	3.08e-212	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GNFHJPHE_01904	7.86e-13	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GNFHJPHE_01905	1.04e-219	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GNFHJPHE_01906	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GNFHJPHE_01907	1.16e-249	-	-	-	EGP	-	-	-	Major Facilitator
GNFHJPHE_01908	2.1e-113	ymdB	-	-	S	-	-	-	Macro domain protein
GNFHJPHE_01909	1.51e-137	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GNFHJPHE_01910	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
GNFHJPHE_01911	8.55e-64	-	-	-	-	-	-	-	-
GNFHJPHE_01912	2.5e-296	-	-	-	S	-	-	-	Putative metallopeptidase domain
GNFHJPHE_01913	1.2e-260	-	-	-	S	-	-	-	associated with various cellular activities
GNFHJPHE_01914	8.15e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
GNFHJPHE_01915	2.01e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
GNFHJPHE_01917	1.43e-152	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
GNFHJPHE_01918	2.25e-70	-	-	-	-	-	-	-	-
GNFHJPHE_01920	2.01e-41	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GNFHJPHE_01921	8.04e-63	-	-	-	-	-	-	-	-
GNFHJPHE_01922	2.62e-262	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
GNFHJPHE_01923	3.36e-289	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
GNFHJPHE_01924	9.02e-317	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GNFHJPHE_01925	1.72e-136	-	-	-	NU	-	-	-	mannosyl-glycoprotein
GNFHJPHE_01926	5.75e-123	-	-	-	S	-	-	-	Putative ABC-transporter type IV
GNFHJPHE_01927	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
GNFHJPHE_01928	4.15e-23	-	-	-	K	-	-	-	Helix-turn-helix domain
GNFHJPHE_01931	2.28e-117	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
GNFHJPHE_01932	1.58e-75	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
GNFHJPHE_01933	1.01e-224	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
GNFHJPHE_01934	6.16e-314	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
GNFHJPHE_01935	8.24e-58	ywfI	-	-	S	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	Chlorite dismutase
GNFHJPHE_01936	8.02e-63	ywfI	-	-	S	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	Chlorite dismutase
GNFHJPHE_01937	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
GNFHJPHE_01938	1.73e-56	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
GNFHJPHE_01939	3.07e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
GNFHJPHE_01940	5.36e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GNFHJPHE_01941	7.84e-72	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
GNFHJPHE_01942	9.73e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
GNFHJPHE_01943	2.7e-18	XK27_09155	-	-	K	-	-	-	Transcriptional
GNFHJPHE_01944	3.81e-32	-	-	-	L	-	-	-	Integrase
GNFHJPHE_01945	5.78e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
GNFHJPHE_01946	5.85e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
GNFHJPHE_01947	4.41e-158	-	-	-	M	-	-	-	PFAM NLP P60 protein
GNFHJPHE_01948	8.68e-231	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
GNFHJPHE_01949	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
GNFHJPHE_01950	4.63e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01951	6.27e-125	-	-	-	P	-	-	-	Cadmium resistance transporter
GNFHJPHE_01952	1.33e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
GNFHJPHE_01953	6.64e-297	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
GNFHJPHE_01954	6.46e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
GNFHJPHE_01955	1.08e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
GNFHJPHE_01956	1.21e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
GNFHJPHE_01957	1.93e-214	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
GNFHJPHE_01958	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GNFHJPHE_01959	1.37e-306	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
GNFHJPHE_01960	3.55e-316	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
GNFHJPHE_01961	7.43e-61	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GNFHJPHE_01962	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
GNFHJPHE_01963	1.7e-54	-	-	-	-	-	-	-	-
GNFHJPHE_01964	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GNFHJPHE_01965	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GNFHJPHE_01966	8.15e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
GNFHJPHE_01967	1.73e-227	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
GNFHJPHE_01968	3.07e-303	-	-	-	L	-	-	-	Transposase
GNFHJPHE_01969	2.74e-183	-	-	-	S	-	-	-	Alpha beta hydrolase
GNFHJPHE_01970	2.68e-275	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GNFHJPHE_01971	1.46e-126	-	-	-	-	-	-	-	-
GNFHJPHE_01973	8.11e-159	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
GNFHJPHE_01974	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
GNFHJPHE_01975	2.49e-141	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
GNFHJPHE_01976	8.57e-114	-	-	-	-	-	-	-	-
GNFHJPHE_01977	2.19e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
GNFHJPHE_01978	1.37e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
GNFHJPHE_01979	1.03e-146	-	-	-	-	-	-	-	-
GNFHJPHE_01980	5.24e-33	-	-	-	-	-	-	-	-
GNFHJPHE_01981	1.54e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
GNFHJPHE_01982	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GNFHJPHE_01983	3.07e-303	-	-	-	L	-	-	-	Transposase
GNFHJPHE_01984	2.02e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
GNFHJPHE_01985	1.61e-48	-	-	-	-	-	-	-	-
GNFHJPHE_01986	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01987	2.37e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GNFHJPHE_01988	3.7e-222	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
GNFHJPHE_01989	5.09e-111	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
GNFHJPHE_01990	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
GNFHJPHE_01991	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
GNFHJPHE_01992	7.84e-246	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
GNFHJPHE_01993	9.36e-42	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
GNFHJPHE_01994	1.78e-75	-	-	-	-	-	-	-	-
GNFHJPHE_01995	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GNFHJPHE_01997	2.97e-272	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
GNFHJPHE_01998	1.25e-131	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
GNFHJPHE_01999	6.09e-83	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
GNFHJPHE_02000	1.34e-312	-	-	-	E	ko:K03294	-	ko00000	amino acid
GNFHJPHE_02001	2.33e-87	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNFHJPHE_02002	8.95e-20	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNFHJPHE_02004	4.15e-280	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
GNFHJPHE_02005	3.33e-39	-	-	-	S	-	-	-	Cytochrome B5
GNFHJPHE_02006	4.97e-97	-	-	-	S	ko:K02348	-	ko00000	Gnat family
GNFHJPHE_02007	1.11e-156	-	-	-	GM	-	-	-	NmrA-like family
GNFHJPHE_02008	1.07e-66	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GNFHJPHE_02009	2.63e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
GNFHJPHE_02010	2.17e-107	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GNFHJPHE_02011	2.91e-294	-	-	-	-	-	-	-	-
GNFHJPHE_02012	4.4e-268	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GNFHJPHE_02013	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
GNFHJPHE_02014	8.37e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
GNFHJPHE_02015	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
GNFHJPHE_02016	7.58e-63	ywnA	-	-	K	-	-	-	Transcriptional regulator
GNFHJPHE_02017	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GNFHJPHE_02018	1.96e-53	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
GNFHJPHE_02019	3.51e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
GNFHJPHE_02020	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
GNFHJPHE_02021	2.41e-156	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
GNFHJPHE_02022	2.9e-186	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
GNFHJPHE_02023	5.92e-76	-	-	-	-	-	-	-	-
GNFHJPHE_02024	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
GNFHJPHE_02025	2.92e-178	-	-	-	T	-	-	-	EAL domain
GNFHJPHE_02026	4.69e-165	-	-	-	F	-	-	-	glutamine amidotransferase
GNFHJPHE_02027	2.57e-78	-	-	-	-	-	-	-	-
GNFHJPHE_02028	3.32e-128	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
GNFHJPHE_02029	1.76e-201	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
GNFHJPHE_02030	1.58e-185	-	-	-	K	-	-	-	Transcriptional regulator
GNFHJPHE_02031	4.01e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
GNFHJPHE_02032	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
GNFHJPHE_02033	1.67e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
GNFHJPHE_02034	4.61e-223	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
GNFHJPHE_02035	1.2e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
GNFHJPHE_02036	6.74e-120	-	-	-	S	-	-	-	Alpha beta hydrolase
GNFHJPHE_02037	3.08e-14	-	-	-	S	-	-	-	Alpha beta hydrolase
GNFHJPHE_02038	0.000156	-	-	-	S	-	-	-	Hydrolases of the alpha beta superfamily
GNFHJPHE_02039	1.9e-84	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
GNFHJPHE_02040	6.36e-21	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
GNFHJPHE_02041	1.09e-97	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
GNFHJPHE_02042	6.71e-148	-	-	-	T	-	-	-	GHKL domain
GNFHJPHE_02043	2.02e-104	-	-	-	T	-	-	-	GHKL domain
GNFHJPHE_02044	3.83e-139	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
GNFHJPHE_02045	1.2e-55	-	-	-	H	-	-	-	RibD C-terminal domain
GNFHJPHE_02046	7.93e-56	-	-	-	H	-	-	-	RibD C-terminal domain
GNFHJPHE_02047	1.52e-73	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GNFHJPHE_02048	3.5e-131	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GNFHJPHE_02049	1.78e-132	-	-	-	NU	-	-	-	MucBP domain
GNFHJPHE_02050	2.2e-172	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GNFHJPHE_02051	2.19e-93	-	-	-	L	-	-	-	Helix-turn-helix domain
GNFHJPHE_02052	1.19e-175	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_02053	2.59e-135	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GNFHJPHE_02054	4.96e-248	flp	-	-	V	-	-	-	Beta-lactamase
GNFHJPHE_02055	2.14e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
GNFHJPHE_02056	1.47e-99	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
GNFHJPHE_02057	1.59e-140	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
GNFHJPHE_02058	2.73e-135	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GNFHJPHE_02059	1.58e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
GNFHJPHE_02060	8.93e-153	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
GNFHJPHE_02061	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
GNFHJPHE_02062	1.52e-239	-	-	-	S	-	-	-	amidohydrolase
GNFHJPHE_02063	5.95e-134	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GNFHJPHE_02064	1.73e-48	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_02066	6.64e-67	-	-	-	L	-	-	-	PFAM Integrase catalytic region
GNFHJPHE_02067	2.45e-63	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
GNFHJPHE_02068	5.59e-20	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
GNFHJPHE_02069	3.47e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GNFHJPHE_02070	4.26e-314	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
GNFHJPHE_02071	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GNFHJPHE_02072	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
GNFHJPHE_02073	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GNFHJPHE_02074	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GNFHJPHE_02075	7.62e-171	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
GNFHJPHE_02076	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GNFHJPHE_02077	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GNFHJPHE_02078	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
GNFHJPHE_02079	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GNFHJPHE_02080	8.88e-133	-	-	-	M	-	-	-	MucBP domain
GNFHJPHE_02081	5.91e-38	-	-	-	L	-	-	-	Helix-turn-helix domain
GNFHJPHE_02082	5.82e-34	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GNFHJPHE_02083	1.27e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GNFHJPHE_02084	2.14e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
GNFHJPHE_02085	3.3e-124	-	-	-	L	-	-	-	Integrase
GNFHJPHE_02086	8.94e-70	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
GNFHJPHE_02087	1.22e-49	-	-	-	K	-	-	-	Helix-turn-helix domain
GNFHJPHE_02089	0.0	-	-	-	-	-	-	-	-
GNFHJPHE_02090	6.08e-197	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
GNFHJPHE_02091	8.43e-54	-	-	-	-	-	-	-	-
GNFHJPHE_02092	2.52e-88	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
GNFHJPHE_02093	1.02e-92	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family