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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
GKDNICOF_00001	2.06e-18	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
GKDNICOF_00002	5.23e-13	-	-	-	T	ko:K07172	-	ko00000,ko02048	SpoVT / AbrB like domain
GKDNICOF_00003	2.04e-205	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GKDNICOF_00004	4.52e-66	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
GKDNICOF_00005	7e-54	-	-	-	-	-	-	-	-
GKDNICOF_00006	1.08e-79	-	-	-	-	-	-	-	-
GKDNICOF_00008	3.17e-107	-	-	-	-	-	-	-	-
GKDNICOF_00009	0.0	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
GKDNICOF_00010	1.79e-119	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2313)
GKDNICOF_00011	2.11e-271	-	-	-	S	-	-	-	Baseplate J-like protein
GKDNICOF_00012	2.09e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
GKDNICOF_00013	2.34e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF2577)
GKDNICOF_00014	1.62e-255	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
GKDNICOF_00015	8.91e-154	xkdP	-	-	S	-	-	-	protein containing LysM domain
GKDNICOF_00016	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
GKDNICOF_00017	3.69e-87	-	-	-	S	-	-	-	Pfam:Phage_TAC_5
GKDNICOF_00018	1.45e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2001)
GKDNICOF_00019	2.04e-308	-	-	-	S	-	-	-	Phage tail sheath C-terminal domain
GKDNICOF_00020	1.35e-42	-	-	-	-	-	-	-	-
GKDNICOF_00021	3.47e-90	-	-	-	-	-	-	-	-
GKDNICOF_00022	1.09e-95	-	-	-	-	-	-	-	-
GKDNICOF_00023	1.38e-82	-	-	-	-	-	-	-	-
GKDNICOF_00024	1.18e-85	-	-	-	-	-	-	-	-
GKDNICOF_00025	1.95e-231	-	-	-	-	-	-	-	-
GKDNICOF_00026	6.6e-67	-	-	-	S	-	-	-	Phage minor structural protein GP20
GKDNICOF_00027	1.08e-244	-	-	-	S	-	-	-	Phage Mu protein F like protein
GKDNICOF_00028	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
GKDNICOF_00029	1.91e-306	-	-	-	S	-	-	-	Terminase-like family
GKDNICOF_00030	5.27e-181	-	-	-	L	-	-	-	NUMOD1 domain
GKDNICOF_00031	3.94e-103	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
GKDNICOF_00032	1.24e-153	-	-	-	-	-	-	-	-
GKDNICOF_00034	4.56e-154	-	-	-	C	-	-	-	Domain of unknown function (DUF4145)
GKDNICOF_00036	4.31e-25	-	-	-	K	-	-	-	chromosome segregation
GKDNICOF_00038	3.85e-125	-	-	-	-	-	-	-	-
GKDNICOF_00039	8.75e-34	-	-	-	-	-	-	-	-
GKDNICOF_00040	3.07e-39	-	-	-	-	-	-	-	-
GKDNICOF_00041	2.91e-50	-	-	-	-	-	-	-	-
GKDNICOF_00043	7.2e-103	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
GKDNICOF_00046	9.65e-09	-	-	-	S	-	-	-	Pfam:DUF5406
GKDNICOF_00047	4.45e-42	-	-	-	-	-	-	-	-
GKDNICOF_00048	2.62e-157	-	-	-	S	-	-	-	AntA/AntB antirepressor
GKDNICOF_00050	2.54e-38	-	-	-	S	-	-	-	sequence-specific DNA binding
GKDNICOF_00051	3.03e-201	-	-	-	S	-	-	-	Conserved phage C-terminus (Phg_2220_C)
GKDNICOF_00052	4.78e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
GKDNICOF_00054	2.81e-74	-	-	-	-	-	-	-	-
GKDNICOF_00055	1.58e-27	-	-	-	-	-	-	-	-
GKDNICOF_00059	5.38e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
GKDNICOF_00061	2.05e-74	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
GKDNICOF_00062	4.21e-105	-	-	-	S	-	-	-	Pfam:Peptidase_M78
GKDNICOF_00063	3.1e-126	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
GKDNICOF_00065	1.22e-154	-	-	-	S	-	-	-	Phage integrase family
GKDNICOF_00066	1.71e-75	-	-	-	-	-	-	-	-
GKDNICOF_00067	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
GKDNICOF_00068	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GKDNICOF_00069	8.32e-125	-	-	-	S	-	-	-	PFAM Archaeal ATPase
GKDNICOF_00070	1.17e-185	-	-	-	EG	-	-	-	EamA-like transporter family
GKDNICOF_00071	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_00072	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GKDNICOF_00073	8.88e-199	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
GKDNICOF_00074	1.6e-96	-	-	-	M	-	-	-	Rib/alpha-like repeat
GKDNICOF_00075	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
GKDNICOF_00076	9.36e-317	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
GKDNICOF_00077	0.0	-	-	-	S	-	-	-	TerB-C domain
GKDNICOF_00078	4.94e-131	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
GKDNICOF_00079	2.18e-75	-	-	-	-	-	-	-	-
GKDNICOF_00080	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
GKDNICOF_00081	4.12e-295	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GKDNICOF_00082	2.88e-191	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GKDNICOF_00083	1.32e-41	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GKDNICOF_00084	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKDNICOF_00085	3.02e-230	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKDNICOF_00086	8.91e-248	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
GKDNICOF_00087	7.59e-271	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
GKDNICOF_00099	1.32e-71	-	-	-	-	-	-	-	-
GKDNICOF_00100	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
GKDNICOF_00101	6.94e-59	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
GKDNICOF_00102	2.25e-111	-	-	-	-	-	-	-	-
GKDNICOF_00103	8.5e-55	-	-	-	-	-	-	-	-
GKDNICOF_00104	8.13e-77	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
GKDNICOF_00105	7.59e-48	-	-	-	-	-	-	-	-
GKDNICOF_00107	8.89e-276	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKDNICOF_00108	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
GKDNICOF_00109	2.56e-145	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
GKDNICOF_00110	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
GKDNICOF_00111	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
GKDNICOF_00112	1.69e-258	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
GKDNICOF_00113	9.87e-159	-	-	-	-	-	-	-	-
GKDNICOF_00114	1.76e-181	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKDNICOF_00115	7.91e-152	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
GKDNICOF_00116	3.68e-200	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GKDNICOF_00117	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
GKDNICOF_00118	3.12e-220	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
GKDNICOF_00119	1.31e-55	-	-	-	-	-	-	-	-
GKDNICOF_00120	2.06e-39	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
GKDNICOF_00121	2.68e-73	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
GKDNICOF_00123	5.89e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
GKDNICOF_00124	2.42e-162	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
GKDNICOF_00125	1.61e-136	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
GKDNICOF_00126	8.12e-104	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
GKDNICOF_00127	1.99e-236	-	-	-	S	-	-	-	Bacteriocin helveticin-J
GKDNICOF_00128	3.81e-126	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
GKDNICOF_00129	7.79e-195	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GKDNICOF_00130	1.2e-165	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
GKDNICOF_00131	2.22e-186	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GKDNICOF_00132	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
GKDNICOF_00133	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
GKDNICOF_00134	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
GKDNICOF_00135	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
GKDNICOF_00136	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
GKDNICOF_00137	2.05e-98	-	-	-	K	-	-	-	acetyltransferase
GKDNICOF_00138	1.46e-167	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
GKDNICOF_00139	1.09e-181	-	-	-	S	-	-	-	hydrolase
GKDNICOF_00140	3.67e-171	-	-	-	K	-	-	-	Transcriptional regulator
GKDNICOF_00141	1.25e-33	-	-	-	S	-	-	-	PFAM Archaeal ATPase
GKDNICOF_00142	4.95e-305	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
GKDNICOF_00143	2.11e-172	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
GKDNICOF_00144	9.37e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
GKDNICOF_00145	1.17e-136	-	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
GKDNICOF_00146	5.07e-166	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
GKDNICOF_00147	2e-110	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKDNICOF_00148	1.81e-67	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GKDNICOF_00149	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
GKDNICOF_00150	3.59e-52	-	-	-	-	-	-	-	-
GKDNICOF_00151	1.12e-140	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
GKDNICOF_00152	1.02e-74	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
GKDNICOF_00153	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
GKDNICOF_00154	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_00155	3.08e-210	-	-	-	K	-	-	-	LysR family
GKDNICOF_00156	0.0	-	-	-	C	-	-	-	FMN_bind
GKDNICOF_00157	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
GKDNICOF_00158	6.7e-211	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
GKDNICOF_00159	3.76e-124	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
GKDNICOF_00160	4.03e-301	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GKDNICOF_00161	2.28e-252	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
GKDNICOF_00162	1.26e-186	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
GKDNICOF_00163	2.03e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
GKDNICOF_00164	2.57e-263	-	-	-	E	-	-	-	Phospholipase B
GKDNICOF_00165	1.06e-313	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
GKDNICOF_00166	7.73e-191	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKDNICOF_00167	4.2e-191	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GKDNICOF_00168	2.51e-152	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GKDNICOF_00169	1.27e-138	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GKDNICOF_00170	2.94e-88	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_00171	0.0	-	-	-	E	-	-	-	Amino acid permease
GKDNICOF_00172	8.59e-272	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
GKDNICOF_00173	1.81e-41	-	-	-	-	-	-	-	-
GKDNICOF_00174	2.67e-91	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GKDNICOF_00175	3.03e-104	-	-	-	-	-	-	-	-
GKDNICOF_00176	2.51e-261	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
GKDNICOF_00177	0.0	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
GKDNICOF_00178	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
GKDNICOF_00179	5e-311	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
GKDNICOF_00180	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
GKDNICOF_00181	5.57e-110	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GKDNICOF_00182	1.9e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
GKDNICOF_00183	9.62e-191	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
GKDNICOF_00184	1.09e-90	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
GKDNICOF_00185	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
GKDNICOF_00186	3.78e-223	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
GKDNICOF_00187	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Glycosyl hydrolases family 31
GKDNICOF_00188	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
GKDNICOF_00189	4.45e-262	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
GKDNICOF_00190	4.52e-187	-	-	-	S	-	-	-	Alpha beta hydrolase
GKDNICOF_00191	1.07e-87	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
GKDNICOF_00192	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_00193	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
GKDNICOF_00194	1.74e-185	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKDNICOF_00195	4.37e-176	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_00196	6.28e-187	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKDNICOF_00197	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKDNICOF_00198	9.28e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKDNICOF_00199	2.35e-54	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_00200	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
GKDNICOF_00201	1.52e-161	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
GKDNICOF_00202	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GKDNICOF_00203	1.08e-112	-	-	-	S	-	-	-	Putative adhesin
GKDNICOF_00204	5.37e-145	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
GKDNICOF_00205	1.42e-259	-	-	-	EGP	-	-	-	Major facilitator superfamily
GKDNICOF_00207	1.85e-236	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
GKDNICOF_00208	1.2e-156	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
GKDNICOF_00209	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GKDNICOF_00210	2.14e-106	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
GKDNICOF_00212	3.91e-41	-	-	-	S	-	-	-	Enterocin A Immunity
GKDNICOF_00216	6.29e-68	-	-	-	S	-	-	-	Enterocin A Immunity
GKDNICOF_00217	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
GKDNICOF_00218	3.16e-197	-	-	-	S	-	-	-	Phospholipase, patatin family
GKDNICOF_00219	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GKDNICOF_00220	1.17e-164	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_00221	8.38e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GKDNICOF_00222	9.27e-203	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
GKDNICOF_00223	1.15e-214	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
GKDNICOF_00224	4.2e-74	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
GKDNICOF_00225	9.89e-113	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
GKDNICOF_00226	3.84e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKDNICOF_00227	2.13e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKDNICOF_00228	1.67e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
GKDNICOF_00229	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GKDNICOF_00230	6.64e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
GKDNICOF_00232	2.06e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKDNICOF_00233	1.01e-159	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GKDNICOF_00234	1.62e-214	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
GKDNICOF_00235	2.4e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
GKDNICOF_00236	3.3e-64	-	-	-	S	-	-	-	Enterocin A Immunity
GKDNICOF_00237	2.31e-165	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
GKDNICOF_00238	7.14e-61	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GKDNICOF_00239	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
GKDNICOF_00240	2.31e-149	-	-	-	C	-	-	-	nitroreductase
GKDNICOF_00241	3.95e-164	-	-	-	-	-	-	-	-
GKDNICOF_00242	6.34e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
GKDNICOF_00243	9.63e-130	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
GKDNICOF_00244	1.21e-294	-	-	-	E	ko:K03294	-	ko00000	amino acid
GKDNICOF_00245	1.69e-174	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GKDNICOF_00246	3.13e-261	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
GKDNICOF_00247	1.5e-315	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKDNICOF_00249	2.13e-273	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKDNICOF_00250	4.59e-108	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
GKDNICOF_00251	3.21e-99	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
GKDNICOF_00252	4.92e-206	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
GKDNICOF_00253	1.13e-198	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
GKDNICOF_00254	1.94e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
GKDNICOF_00255	2.38e-88	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_00256	1.6e-76	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_00257	4.25e-223	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_00258	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GKDNICOF_00259	7.25e-88	-	-	-	O	-	-	-	OsmC-like protein
GKDNICOF_00260	1.12e-144	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
GKDNICOF_00261	5.85e-149	dltr	-	-	K	-	-	-	response regulator
GKDNICOF_00262	4.41e-290	sptS	-	-	T	-	-	-	Histidine kinase
GKDNICOF_00263	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GKDNICOF_00264	7.54e-103	-	-	-	-	-	-	-	-
GKDNICOF_00265	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
GKDNICOF_00266	2.87e-171	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GKDNICOF_00267	1.09e-156	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GKDNICOF_00269	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKDNICOF_00270	1.47e-87	-	-	-	-	-	-	-	-
GKDNICOF_00271	8.69e-130	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
GKDNICOF_00272	2.75e-268	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
GKDNICOF_00273	7.19e-159	pnb	-	-	C	-	-	-	nitroreductase
GKDNICOF_00274	2.15e-111	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
GKDNICOF_00275	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
GKDNICOF_00276	2.98e-89	-	-	-	K	-	-	-	MerR HTH family regulatory protein
GKDNICOF_00277	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GKDNICOF_00278	4.01e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
GKDNICOF_00279	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
GKDNICOF_00280	5.28e-208	-	-	-	GK	-	-	-	ROK family
GKDNICOF_00281	5.48e-203	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GKDNICOF_00282	1.18e-222	-	-	-	I	-	-	-	Carboxylesterase family
GKDNICOF_00283	3.9e-256	-	-	-	P	-	-	-	Major Facilitator Superfamily
GKDNICOF_00284	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
GKDNICOF_00285	3.9e-72	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GKDNICOF_00286	2.03e-69	-	-	-	-	-	-	-	-
GKDNICOF_00287	2.85e-151	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
GKDNICOF_00288	3.35e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
GKDNICOF_00289	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
GKDNICOF_00290	1.17e-17	-	-	-	-	-	-	-	-
GKDNICOF_00291	4.19e-287	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
GKDNICOF_00292	3.01e-189	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKDNICOF_00293	1.33e-79	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
GKDNICOF_00294	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
GKDNICOF_00295	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
GKDNICOF_00296	6.58e-251	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GKDNICOF_00297	6.05e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKDNICOF_00298	1.47e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
GKDNICOF_00299	1.6e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKDNICOF_00300	3.54e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKDNICOF_00301	9.12e-317	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKDNICOF_00302	1.93e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKDNICOF_00303	9.08e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GKDNICOF_00304	4.68e-193	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
GKDNICOF_00305	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
GKDNICOF_00306	3.49e-63	-	-	-	-	-	-	-	-
GKDNICOF_00307	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
GKDNICOF_00308	1.63e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GKDNICOF_00309	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKDNICOF_00310	8.91e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKDNICOF_00311	6.07e-292	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKDNICOF_00312	7.45e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
GKDNICOF_00313	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
GKDNICOF_00314	1.15e-202	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GKDNICOF_00315	2.41e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
GKDNICOF_00316	3.66e-148	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
GKDNICOF_00317	9.04e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
GKDNICOF_00318	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
GKDNICOF_00319	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
GKDNICOF_00320	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKDNICOF_00321	2.18e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GKDNICOF_00322	6.2e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKDNICOF_00323	5.08e-243	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GKDNICOF_00324	2.91e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GKDNICOF_00325	3.16e-232	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKDNICOF_00326	2.24e-208	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GKDNICOF_00327	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GKDNICOF_00328	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GKDNICOF_00329	3.54e-157	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GKDNICOF_00330	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
GKDNICOF_00331	5.26e-219	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKDNICOF_00332	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GKDNICOF_00333	1.17e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKDNICOF_00334	4.67e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKDNICOF_00335	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
GKDNICOF_00336	2.51e-115	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKDNICOF_00337	3.36e-170	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
GKDNICOF_00338	3.71e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GKDNICOF_00339	2.49e-149	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GKDNICOF_00340	3.02e-92	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
GKDNICOF_00341	4.88e-142	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
GKDNICOF_00342	3.88e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKDNICOF_00343	2.31e-44	ynzC	-	-	S	-	-	-	UPF0291 protein
GKDNICOF_00344	4.85e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
GKDNICOF_00345	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKDNICOF_00346	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKDNICOF_00347	2.64e-286	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
GKDNICOF_00348	3.48e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
GKDNICOF_00349	6.78e-244	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
GKDNICOF_00350	4.34e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
GKDNICOF_00351	2.8e-232	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKDNICOF_00352	7.13e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
GKDNICOF_00353	2.87e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GKDNICOF_00354	3.53e-168	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKDNICOF_00355	1.37e-177	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
GKDNICOF_00356	3.5e-290	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
GKDNICOF_00357	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GKDNICOF_00358	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKDNICOF_00359	1.62e-106	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
GKDNICOF_00360	1.63e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
GKDNICOF_00361	1.08e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
GKDNICOF_00362	8.97e-62	-	-	-	J	-	-	-	ribosomal protein
GKDNICOF_00363	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKDNICOF_00364	6.74e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKDNICOF_00365	1.03e-205	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKDNICOF_00366	1.8e-218	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
GKDNICOF_00367	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
GKDNICOF_00368	1.15e-144	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
GKDNICOF_00369	4.59e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GKDNICOF_00370	2.65e-108	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKDNICOF_00371	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
GKDNICOF_00372	6.72e-250	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GKDNICOF_00373	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GKDNICOF_00374	5.2e-156	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
GKDNICOF_00375	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
GKDNICOF_00376	1.7e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKDNICOF_00377	0.0	potE	-	-	E	-	-	-	Amino Acid
GKDNICOF_00378	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKDNICOF_00379	5.93e-236	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKDNICOF_00380	1.57e-112	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKDNICOF_00381	1.68e-311	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GKDNICOF_00382	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
GKDNICOF_00383	6.12e-195	lysR5	-	-	K	-	-	-	LysR substrate binding domain
GKDNICOF_00385	2e-129	-	-	-	I	-	-	-	PAP2 superfamily
GKDNICOF_00386	6.08e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKDNICOF_00387	6.93e-41	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
GKDNICOF_00388	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
GKDNICOF_00389	3e-208	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GKDNICOF_00390	1.35e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
GKDNICOF_00391	1.53e-184	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
GKDNICOF_00392	4.71e-94	-	-	-	L	-	-	-	nuclease
GKDNICOF_00393	2.71e-199	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GKDNICOF_00394	1.7e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKDNICOF_00395	7.36e-126	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKDNICOF_00396	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GKDNICOF_00397	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
GKDNICOF_00398	4.22e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GKDNICOF_00399	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
GKDNICOF_00400	6.92e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
GKDNICOF_00401	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
GKDNICOF_00402	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
GKDNICOF_00403	9.43e-111	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKDNICOF_00404	6.22e-216	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
GKDNICOF_00405	2.32e-86	-	-	-	-	-	-	-	-
GKDNICOF_00406	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKDNICOF_00407	1.6e-93	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GKDNICOF_00408	2.37e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
GKDNICOF_00409	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GKDNICOF_00410	1.14e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GKDNICOF_00411	1.23e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
GKDNICOF_00412	8.3e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
GKDNICOF_00413	7.25e-129	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKDNICOF_00414	1.71e-206	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKDNICOF_00415	3.84e-200	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GKDNICOF_00416	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
GKDNICOF_00417	7.69e-77	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
GKDNICOF_00418	2.37e-222	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
GKDNICOF_00419	3.57e-125	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKDNICOF_00420	6.75e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKDNICOF_00421	4.63e-174	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
GKDNICOF_00422	3.68e-228	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
GKDNICOF_00423	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
GKDNICOF_00424	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKDNICOF_00425	2.29e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKDNICOF_00426	2.25e-140	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
GKDNICOF_00427	1.05e-182	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKDNICOF_00428	4.24e-310	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
GKDNICOF_00429	4.24e-78	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
GKDNICOF_00430	2.22e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
GKDNICOF_00431	3.36e-164	-	-	-	-	-	-	-	-
GKDNICOF_00432	2.19e-147	-	-	-	-	-	-	-	-
GKDNICOF_00433	1.45e-30	-	-	-	-	-	-	-	-
GKDNICOF_00434	4.43e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GKDNICOF_00435	2.17e-162	-	-	-	-	-	-	-	-
GKDNICOF_00436	3.87e-215	-	-	-	-	-	-	-	-
GKDNICOF_00437	7.99e-296	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
GKDNICOF_00438	4.01e-65	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
GKDNICOF_00439	2.17e-209	-	-	-	S	-	-	-	DUF218 domain
GKDNICOF_00440	1.74e-185	yxeH	-	-	S	-	-	-	hydrolase
GKDNICOF_00441	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
GKDNICOF_00442	1.11e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKDNICOF_00443	3.96e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GKDNICOF_00444	5.91e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GKDNICOF_00445	9.72e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKDNICOF_00446	7.72e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
GKDNICOF_00447	1.45e-297	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GKDNICOF_00448	1.47e-265	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GKDNICOF_00449	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GKDNICOF_00450	9.76e-120	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKDNICOF_00451	3.83e-132	pncA	-	-	Q	-	-	-	Isochorismatase family
GKDNICOF_00452	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GKDNICOF_00453	1.05e-152	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
GKDNICOF_00455	2.87e-158	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_00456	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
GKDNICOF_00457	8.69e-118	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
GKDNICOF_00458	1.58e-59	-	-	-	K	-	-	-	LysR substrate binding domain
GKDNICOF_00459	2.92e-305	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GKDNICOF_00460	5.55e-85	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GKDNICOF_00461	5.77e-25	-	-	-	-	-	-	-	-
GKDNICOF_00462	1.53e-118	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
GKDNICOF_00463	7.37e-17	-	-	-	-	-	-	-	-
GKDNICOF_00464	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
GKDNICOF_00465	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GKDNICOF_00466	6.08e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKDNICOF_00467	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
GKDNICOF_00468	2.72e-266	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
GKDNICOF_00469	4.58e-188	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GKDNICOF_00470	6.19e-294	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKDNICOF_00471	2.18e-199	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
GKDNICOF_00472	9.64e-185	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
GKDNICOF_00473	7.32e-211	purR13	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
GKDNICOF_00474	0.0	-	-	-	G	-	-	-	isomerase
GKDNICOF_00475	9.09e-270	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
GKDNICOF_00476	6.73e-182	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
GKDNICOF_00477	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GKDNICOF_00478	1.24e-204	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GKDNICOF_00479	1.64e-167	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
GKDNICOF_00480	1.74e-220	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
GKDNICOF_00481	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5060)
GKDNICOF_00483	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
GKDNICOF_00484	7.75e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GKDNICOF_00485	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain
GKDNICOF_00486	2.04e-225	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
GKDNICOF_00487	8.96e-128	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
GKDNICOF_00488	9.73e-213	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
GKDNICOF_00489	1.58e-07	nlhH_1	-	-	I	ko:K01066	-	ko00000,ko01000	acetylesterase activity
GKDNICOF_00490	0.0	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
GKDNICOF_00491	1.61e-173	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GKDNICOF_00492	9.9e-44	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
GKDNICOF_00493	3.7e-151	-	-	-	C	-	-	-	nitroreductase
GKDNICOF_00494	8.32e-35	-	-	-	-	-	-	-	-
GKDNICOF_00495	4.32e-46	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GKDNICOF_00496	3.03e-37	-	-	-	K	ko:K03488	-	ko00000,ko03000	Psort location Cytoplasmic, score
GKDNICOF_00497	1.31e-132	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GKDNICOF_00498	1.99e-68	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GKDNICOF_00499	2.84e-110	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
GKDNICOF_00500	1.64e-16	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
GKDNICOF_00501	1.31e-86	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
GKDNICOF_00502	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GKDNICOF_00503	5.25e-151	-	-	-	-	-	-	-	-
GKDNICOF_00504	2.79e-125	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
GKDNICOF_00505	5.83e-89	-	-	-	K	-	-	-	sequence-specific DNA binding
GKDNICOF_00506	5.26e-171	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
GKDNICOF_00507	1.82e-180	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
GKDNICOF_00508	5.07e-173	-	-	-	K	-	-	-	Helix-turn-helix domain
GKDNICOF_00509	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
GKDNICOF_00510	4.26e-103	yfhC	-	-	C	-	-	-	nitroreductase
GKDNICOF_00511	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
GKDNICOF_00512	5.63e-63	-	-	-	-	-	-	-	-
GKDNICOF_00513	5.12e-96	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GKDNICOF_00514	4.34e-63	-	-	-	S	-	-	-	MazG-like family
GKDNICOF_00515	1.62e-76	-	-	-	-	-	-	-	-
GKDNICOF_00516	1.32e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
GKDNICOF_00517	9.95e-25	-	-	-	S	-	-	-	Fic/DOC family
GKDNICOF_00518	4.16e-119	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GKDNICOF_00519	3.38e-109	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
GKDNICOF_00521	1.14e-52	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
GKDNICOF_00522	7.37e-61	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
GKDNICOF_00523	5.82e-244	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
GKDNICOF_00524	2.11e-80	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
GKDNICOF_00525	1.31e-153	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
GKDNICOF_00527	3.39e-55	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
GKDNICOF_00528	1.91e-107	-	-	-	S	-	-	-	AAA domain
GKDNICOF_00529	9.25e-86	-	-	-	F	-	-	-	NUDIX domain
GKDNICOF_00530	4.08e-170	-	-	-	F	-	-	-	Phosphorylase superfamily
GKDNICOF_00531	9.93e-99	-	-	-	S	-	-	-	ASCH
GKDNICOF_00532	1.09e-82	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GKDNICOF_00533	1.06e-202	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
GKDNICOF_00534	1.92e-196	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
GKDNICOF_00535	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
GKDNICOF_00536	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
GKDNICOF_00537	5.4e-230	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GKDNICOF_00538	4.68e-256	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
GKDNICOF_00539	5.73e-215	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
GKDNICOF_00540	2.06e-204	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
GKDNICOF_00541	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GKDNICOF_00542	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
GKDNICOF_00543	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
GKDNICOF_00544	2.36e-111	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
GKDNICOF_00545	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
GKDNICOF_00546	9.3e-138	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
GKDNICOF_00547	7.5e-146	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKDNICOF_00548	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
GKDNICOF_00549	3.29e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKDNICOF_00550	4.43e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
GKDNICOF_00551	7.32e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GKDNICOF_00552	5.79e-269	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
GKDNICOF_00553	3.53e-295	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GKDNICOF_00554	1.46e-216	degV1	-	-	S	-	-	-	DegV family
GKDNICOF_00555	1.65e-69	-	-	-	-	-	-	-	-
GKDNICOF_00556	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
GKDNICOF_00557	4.84e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKDNICOF_00558	2.97e-213	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GKDNICOF_00559	3.8e-251	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GKDNICOF_00560	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GKDNICOF_00561	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
GKDNICOF_00562	5.5e-83	-	-	-	-	-	-	-	-
GKDNICOF_00563	1.07e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
GKDNICOF_00564	6.17e-189	-	-	-	-	-	-	-	-
GKDNICOF_00565	1.77e-186	lysR	-	-	K	-	-	-	Transcriptional regulator
GKDNICOF_00566	1.32e-249	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
GKDNICOF_00567	1.5e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
GKDNICOF_00568	2.65e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKDNICOF_00569	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
GKDNICOF_00570	3.5e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
GKDNICOF_00571	6.78e-221	-	-	-	K	-	-	-	Transcriptional regulator
GKDNICOF_00572	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKDNICOF_00573	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKDNICOF_00574	5.86e-148	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKDNICOF_00575	5.49e-146	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
GKDNICOF_00576	7.95e-140	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
GKDNICOF_00577	4.35e-204	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
GKDNICOF_00578	1.65e-58	-	-	-	C	-	-	-	Aldo/keto reductase family
GKDNICOF_00579	4.5e-150	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
GKDNICOF_00580	1.12e-239	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
GKDNICOF_00581	2.15e-186	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
GKDNICOF_00582	2.35e-38	-	-	-	-	-	-	-	-
GKDNICOF_00583	4.37e-37	-	-	-	-	-	-	-	-
GKDNICOF_00584	2.45e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
GKDNICOF_00585	1.34e-136	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
GKDNICOF_00586	7.29e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
GKDNICOF_00587	6.15e-154	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GKDNICOF_00588	2.87e-107	-	-	-	K	-	-	-	GNAT family
GKDNICOF_00589	1.06e-257	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
GKDNICOF_00590	1.64e-19	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
GKDNICOF_00591	8.4e-96	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
GKDNICOF_00592	1.27e-39	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	general stress protein
GKDNICOF_00593	1.14e-95	ogt	2.1.1.63	-	L	ko:K00567,ko:K10778	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
GKDNICOF_00594	2.64e-62	-	-	-	K	-	-	-	Transcriptional regulator
GKDNICOF_00595	3.23e-18	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
GKDNICOF_00596	4.62e-33	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
GKDNICOF_00597	7.03e-111	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
GKDNICOF_00598	3.44e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
GKDNICOF_00599	1.02e-143	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
GKDNICOF_00600	1.09e-123	dpsB	-	-	P	-	-	-	Belongs to the Dps family
GKDNICOF_00601	3.88e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
GKDNICOF_00602	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
GKDNICOF_00603	2.69e-12	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
GKDNICOF_00604	4.05e-137	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_00605	1.39e-88	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
GKDNICOF_00606	3.78e-219	yobV3	-	-	K	-	-	-	WYL domain
GKDNICOF_00607	4.15e-36	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GKDNICOF_00608	1.7e-101	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GKDNICOF_00609	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
GKDNICOF_00610	1.22e-39	-	-	-	G	ko:K03292	-	ko00000	Major facilitator Superfamily
GKDNICOF_00611	2.2e-77	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
GKDNICOF_00612	1.27e-272	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
GKDNICOF_00613	5.47e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
GKDNICOF_00614	8.22e-292	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF1100)
GKDNICOF_00615	1.24e-129	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
GKDNICOF_00617	3.82e-189	-	-	-	C	-	-	-	Aldo keto reductase
GKDNICOF_00618	3.56e-204	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
GKDNICOF_00619	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
GKDNICOF_00620	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
GKDNICOF_00621	1.04e-15	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GKDNICOF_00622	7.39e-95	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GKDNICOF_00623	0.0	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
GKDNICOF_00624	4.53e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GKDNICOF_00625	3.04e-312	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GKDNICOF_00626	7.82e-97	-	-	-	S	-	-	-	Cupin domain
GKDNICOF_00627	7.02e-141	-	-	-	S	-	-	-	Fic/DOC family
GKDNICOF_00628	2.55e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
GKDNICOF_00629	6.93e-61	-	-	-	K	-	-	-	LytTr DNA-binding domain
GKDNICOF_00630	2.54e-117	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
GKDNICOF_00631	3.44e-146	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKDNICOF_00632	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
GKDNICOF_00633	0.0	-	-	-	P	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
GKDNICOF_00634	1.27e-271	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
GKDNICOF_00635	1.89e-62	-	-	-	-	-	-	-	-
GKDNICOF_00636	1.27e-84	-	-	-	K	-	-	-	HxlR family
GKDNICOF_00637	9.31e-120	-	3.1.1.81	-	S	ko:K13075	ko02024,map02024	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
GKDNICOF_00638	8.75e-317	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GKDNICOF_00639	5.75e-78	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
GKDNICOF_00640	1.07e-153	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
GKDNICOF_00641	1.47e-138	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
GKDNICOF_00642	0.0	-	-	-	-	-	-	-	-
GKDNICOF_00643	0.0	-	-	-	M	-	-	-	domain protein
GKDNICOF_00644	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKDNICOF_00645	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKDNICOF_00648	0.0	-	-	-	S	-	-	-	domain, Protein
GKDNICOF_00649	9.72e-135	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
GKDNICOF_00650	9.65e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
GKDNICOF_00651	1.02e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
GKDNICOF_00652	7.29e-146	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
GKDNICOF_00653	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GKDNICOF_00654	1.85e-163	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
GKDNICOF_00655	1.42e-131	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_00656	6.43e-152	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_00657	4.23e-54	-	-	-	-	-	-	-	-
GKDNICOF_00658	1.55e-62	-	-	-	-	-	-	-	-
GKDNICOF_00659	1.05e-285	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
GKDNICOF_00660	2.1e-47	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
GKDNICOF_00661	3.6e-242	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
GKDNICOF_00662	1.43e-112	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
GKDNICOF_00663	4.72e-186	-	-	-	K	-	-	-	Transcriptional regulator
GKDNICOF_00664	6.71e-243	tanA	-	-	S	-	-	-	alpha beta
GKDNICOF_00665	2.09e-26	-	-	-	K	-	-	-	LysR substrate binding domain
GKDNICOF_00666	2.02e-226	-	-	-	S	-	-	-	Conserved hypothetical protein 698
GKDNICOF_00667	3.58e-78	-	-	-	-	-	-	-	-
GKDNICOF_00669	7.94e-128	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
GKDNICOF_00670	6.2e-121	-	-	-	K	-	-	-	LysR substrate binding domain
GKDNICOF_00671	3.81e-225	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
GKDNICOF_00672	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GKDNICOF_00673	7.75e-115	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GKDNICOF_00674	4.07e-217	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
GKDNICOF_00675	2.21e-310	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GKDNICOF_00676	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKDNICOF_00677	1.14e-194	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
GKDNICOF_00678	2.76e-166	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKDNICOF_00679	4.71e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKDNICOF_00680	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
GKDNICOF_00681	7.56e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
GKDNICOF_00682	2.88e-190	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
GKDNICOF_00683	6.55e-146	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
GKDNICOF_00684	6.92e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKDNICOF_00685	2.23e-204	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKDNICOF_00686	5.87e-229	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
GKDNICOF_00688	1.99e-211	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
GKDNICOF_00689	0.0	-	-	-	C	-	-	-	FMN_bind
GKDNICOF_00690	1.85e-30	-	-	-	S	-	-	-	Carotenoid biosynthesis protein
GKDNICOF_00692	4.01e-115	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
GKDNICOF_00693	6.67e-188	-	-	-	-	-	-	-	-
GKDNICOF_00694	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
GKDNICOF_00696	1.8e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
GKDNICOF_00697	7.91e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKDNICOF_00698	5.59e-307	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
GKDNICOF_00699	5.27e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
GKDNICOF_00700	2.42e-150	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
GKDNICOF_00701	2.52e-124	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKDNICOF_00702	3.83e-84	-	-	-	M	-	-	-	Lysin motif
GKDNICOF_00703	1.65e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GKDNICOF_00704	4.87e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKDNICOF_00705	1.18e-170	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKDNICOF_00706	3.25e-81	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
GKDNICOF_00707	3.22e-216	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
GKDNICOF_00708	2.25e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
GKDNICOF_00709	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
GKDNICOF_00710	1.69e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GKDNICOF_00711	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
GKDNICOF_00712	1.57e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
GKDNICOF_00713	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GKDNICOF_00714	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
GKDNICOF_00715	1.89e-61	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
GKDNICOF_00716	1.61e-181	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
GKDNICOF_00717	3.12e-222	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GKDNICOF_00718	0.0	oatA	-	-	I	-	-	-	Acyltransferase
GKDNICOF_00719	7.29e-304	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKDNICOF_00720	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GKDNICOF_00721	1.54e-217	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
GKDNICOF_00722	3.86e-136	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
GKDNICOF_00723	8.52e-139	-	-	-	GM	-	-	-	NmrA-like family
GKDNICOF_00724	5.05e-313	yagE	-	-	E	-	-	-	amino acid
GKDNICOF_00725	9.05e-123	-	-	-	S	-	-	-	Rib/alpha-like repeat
GKDNICOF_00726	2.11e-74	-	-	-	S	-	-	-	Domain of unknown function DUF1828
GKDNICOF_00727	1.74e-86	-	-	-	-	-	-	-	-
GKDNICOF_00728	2.87e-48	-	-	-	-	-	-	-	-
GKDNICOF_00729	1.87e-102	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
GKDNICOF_00730	1.67e-102	-	-	-	-	-	-	-	-
GKDNICOF_00731	3.29e-206	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
GKDNICOF_00732	9.04e-98	-	-	-	S	-	-	-	HIRAN
GKDNICOF_00733	6.67e-129	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
GKDNICOF_00734	6.27e-249	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_00735	2.13e-71	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
GKDNICOF_00736	2e-103	-	-	-	-	-	-	-	-
GKDNICOF_00737	3.09e-62	-	-	-	L	-	-	-	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKDNICOF_00740	2.88e-112	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
GKDNICOF_00741	3.84e-83	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
GKDNICOF_00742	5.44e-129	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKDNICOF_00743	1.22e-105	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKDNICOF_00744	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GKDNICOF_00745	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKDNICOF_00746	1.12e-166	-	-	-	S	-	-	-	membrane
GKDNICOF_00747	2.48e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
GKDNICOF_00748	2.27e-126	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
GKDNICOF_00749	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKDNICOF_00750	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
GKDNICOF_00751	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
GKDNICOF_00752	0.0	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GKDNICOF_00753	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
GKDNICOF_00754	8.4e-185	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GKDNICOF_00755	6.29e-296	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GKDNICOF_00756	1.96e-69	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
GKDNICOF_00757	2.75e-64	-	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
GKDNICOF_00758	3.2e-95	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
GKDNICOF_00759	6.32e-311	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKDNICOF_00760	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKDNICOF_00761	5.74e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKDNICOF_00762	6.65e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
GKDNICOF_00763	4.12e-62	-	-	-	-	-	-	-	-
GKDNICOF_00764	3.5e-282	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GKDNICOF_00765	3.16e-137	-	-	-	-	-	-	-	-
GKDNICOF_00766	2.88e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKDNICOF_00767	1.34e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
GKDNICOF_00768	1.09e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
GKDNICOF_00769	2.33e-112	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
GKDNICOF_00770	5.81e-165	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
GKDNICOF_00771	1.62e-196	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKDNICOF_00772	1.12e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
GKDNICOF_00773	1.28e-193	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GKDNICOF_00774	1.66e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
GKDNICOF_00775	1.87e-142	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKDNICOF_00776	3.68e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
GKDNICOF_00777	4.38e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKDNICOF_00778	5.45e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKDNICOF_00779	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKDNICOF_00780	1.2e-104	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GKDNICOF_00781	6.96e-33	-	-	-	-	-	-	-	-
GKDNICOF_00782	8.07e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
GKDNICOF_00783	1.32e-43	-	-	-	-	-	-	-	-
GKDNICOF_00784	1.01e-194	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
GKDNICOF_00785	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GKDNICOF_00786	2.35e-126	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKDNICOF_00787	2.04e-169	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
GKDNICOF_00788	8.36e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
GKDNICOF_00789	5.35e-140	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GKDNICOF_00790	6.1e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GKDNICOF_00791	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKDNICOF_00792	6.09e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
GKDNICOF_00793	9.78e-18	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GKDNICOF_00794	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GKDNICOF_00795	1.55e-54	-	-	-	S	-	-	-	CAAX protease self-immunity
GKDNICOF_00797	5.93e-237	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GKDNICOF_00798	5.98e-285	-	-	-	G	-	-	-	Major Facilitator Superfamily
GKDNICOF_00799	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKDNICOF_00800	4.58e-250	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
GKDNICOF_00801	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
GKDNICOF_00802	5.9e-46	-	-	-	-	-	-	-	-
GKDNICOF_00803	6.82e-128	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
GKDNICOF_00804	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_00805	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
GKDNICOF_00806	9e-74	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
GKDNICOF_00807	2.67e-191	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
GKDNICOF_00808	5.44e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKDNICOF_00809	8.55e-99	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKDNICOF_00810	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GKDNICOF_00811	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKDNICOF_00812	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKDNICOF_00813	3.02e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
GKDNICOF_00814	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
GKDNICOF_00815	8.09e-235	-	-	-	S	-	-	-	AAA domain
GKDNICOF_00816	1.74e-162	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKDNICOF_00817	1.28e-33	-	-	-	-	-	-	-	-
GKDNICOF_00818	1.54e-55	-	-	-	-	-	-	-	-
GKDNICOF_00819	1.96e-197	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
GKDNICOF_00820	4.57e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
GKDNICOF_00821	2.92e-162	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
GKDNICOF_00822	2.1e-140	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
GKDNICOF_00823	4.13e-196	-	-	-	GM	-	-	-	NmrA-like family
GKDNICOF_00824	1e-110	-	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
GKDNICOF_00825	3.19e-89	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
GKDNICOF_00826	1.35e-133	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_00827	7.96e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
GKDNICOF_00828	7.82e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKDNICOF_00829	6.38e-190	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GKDNICOF_00830	8.53e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKDNICOF_00831	4.62e-193	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKDNICOF_00832	1.11e-184	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKDNICOF_00833	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
GKDNICOF_00834	4.41e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKDNICOF_00835	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKDNICOF_00836	4.53e-72	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKDNICOF_00837	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
GKDNICOF_00838	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKDNICOF_00839	1.98e-154	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GKDNICOF_00840	2.42e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKDNICOF_00841	5.78e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GKDNICOF_00842	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
GKDNICOF_00843	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKDNICOF_00844	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKDNICOF_00845	1.69e-119	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKDNICOF_00846	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKDNICOF_00847	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKDNICOF_00848	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKDNICOF_00849	1.67e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKDNICOF_00850	8.55e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKDNICOF_00851	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKDNICOF_00852	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
GKDNICOF_00853	4.26e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKDNICOF_00854	3.04e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKDNICOF_00855	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKDNICOF_00856	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKDNICOF_00857	4.01e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKDNICOF_00858	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GKDNICOF_00859	3.16e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
GKDNICOF_00860	8.75e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKDNICOF_00861	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
GKDNICOF_00862	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKDNICOF_00863	1.62e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GKDNICOF_00864	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKDNICOF_00865	5.75e-142	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
GKDNICOF_00866	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKDNICOF_00867	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKDNICOF_00868	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GKDNICOF_00871	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
GKDNICOF_00872	1.25e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKDNICOF_00873	8.83e-203	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKDNICOF_00874	0.0	-	-	-	S	-	-	-	membrane
GKDNICOF_00875	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKDNICOF_00876	2.89e-291	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GKDNICOF_00877	6.12e-76	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
GKDNICOF_00878	5.29e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
GKDNICOF_00879	1.75e-46	yabO	-	-	J	-	-	-	S4 domain protein
GKDNICOF_00880	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKDNICOF_00881	6.33e-133	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GKDNICOF_00882	2.31e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GKDNICOF_00883	5.46e-161	-	-	-	S	-	-	-	(CBS) domain
GKDNICOF_00884	1e-270	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKDNICOF_00885	2.39e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GKDNICOF_00886	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GKDNICOF_00887	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GKDNICOF_00888	1.28e-54	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
GKDNICOF_00889	0.0	-	-	-	E	-	-	-	amino acid
GKDNICOF_00890	3.5e-171	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_00891	1.4e-181	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
GKDNICOF_00892	2.57e-222	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
GKDNICOF_00893	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
GKDNICOF_00894	2.88e-290	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKDNICOF_00895	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GKDNICOF_00897	1.51e-89	-	-	-	-	-	-	-	-
GKDNICOF_00898	2.61e-76	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
GKDNICOF_00899	6.52e-41	-	-	-	-	-	-	-	-
GKDNICOF_00900	3.31e-264	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GKDNICOF_00901	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GKDNICOF_00902	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GKDNICOF_00903	1.97e-123	-	-	-	-	-	-	-	-
GKDNICOF_00904	4.73e-67	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKDNICOF_00905	1.69e-97	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
GKDNICOF_00906	9.59e-45	-	-	-	-	-	-	-	-
GKDNICOF_00909	2.55e-136	-	-	-	S	-	-	-	Flavodoxin-like fold
GKDNICOF_00910	4.14e-115	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GKDNICOF_00911	3.2e-10	-	-	-	-	-	-	-	-
GKDNICOF_00912	3.71e-16	-	-	-	-	-	-	-	-
GKDNICOF_00913	5.33e-222	-	-	-	K	-	-	-	Helix-turn-helix
GKDNICOF_00915	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
GKDNICOF_00916	1.98e-166	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
GKDNICOF_00917	1.31e-133	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GKDNICOF_00918	1.79e-302	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
GKDNICOF_00919	9.93e-164	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
GKDNICOF_00920	8.5e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKDNICOF_00921	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GKDNICOF_00922	3.78e-92	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GKDNICOF_00923	1.85e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
GKDNICOF_00924	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GKDNICOF_00925	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
GKDNICOF_00926	4.16e-199	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKDNICOF_00927	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GKDNICOF_00928	6.43e-293	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
GKDNICOF_00929	4.76e-269	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GKDNICOF_00930	2.58e-147	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
GKDNICOF_00931	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
GKDNICOF_00932	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
GKDNICOF_00933	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
GKDNICOF_00934	2.48e-226	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
GKDNICOF_00935	3.75e-222	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKDNICOF_00936	4.64e-310	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKDNICOF_00937	7.45e-194	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
GKDNICOF_00938	2.99e-49	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
GKDNICOF_00939	1.66e-195	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GKDNICOF_00940	1.08e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKDNICOF_00941	1.75e-181	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
GKDNICOF_00942	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKDNICOF_00943	7.23e-67	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
GKDNICOF_00944	1.71e-34	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
GKDNICOF_00945	2.82e-125	-	-	-	S	ko:K06872	-	ko00000	TPM domain
GKDNICOF_00946	6.82e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
GKDNICOF_00947	1.36e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GKDNICOF_00948	7.24e-141	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
GKDNICOF_00950	2.18e-139	-	-	-	-	-	-	-	-
GKDNICOF_00951	5.91e-190	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
GKDNICOF_00952	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_00953	9.79e-187	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKDNICOF_00954	3.91e-117	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKDNICOF_00955	3.44e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GKDNICOF_00956	1.34e-51	-	-	-	-	-	-	-	-
GKDNICOF_00957	1.76e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
GKDNICOF_00958	3.39e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
GKDNICOF_00959	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_00960	3.67e-162	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
GKDNICOF_00961	4.62e-316	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKDNICOF_00962	6.64e-102	-	-	-	-	-	-	-	-
GKDNICOF_00963	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_00964	1.47e-100	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GKDNICOF_00965	1.63e-99	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKDNICOF_00966	5.81e-55	-	-	-	-	-	-	-	-
GKDNICOF_00967	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
GKDNICOF_00968	3.53e-53	-	-	-	K	-	-	-	sequence-specific DNA binding
GKDNICOF_00969	7.76e-152	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GKDNICOF_00970	1.06e-314	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
GKDNICOF_00972	2.42e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKDNICOF_00973	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
GKDNICOF_00974	7.62e-144	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKDNICOF_00975	4.09e-254	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GKDNICOF_00976	2.08e-210	-	-	-	G	-	-	-	Aldose 1-epimerase
GKDNICOF_00977	1.49e-193	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
GKDNICOF_00978	1.53e-146	-	-	-	-	-	-	-	-
GKDNICOF_00979	1.56e-227	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
GKDNICOF_00980	3.78e-92	-	-	-	S	-	-	-	GtrA-like protein
GKDNICOF_00981	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKDNICOF_00982	1.03e-58	-	-	-	V	-	-	-	Abi-like protein
GKDNICOF_00983	1.11e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKDNICOF_00984	4.49e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
GKDNICOF_00985	1.03e-178	-	-	-	-	-	-	-	-
GKDNICOF_00986	8.06e-164	-	-	-	-	-	-	-	-
GKDNICOF_00987	7.86e-217	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
GKDNICOF_00988	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
GKDNICOF_00989	5.99e-184	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
GKDNICOF_00990	3.67e-26	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GKDNICOF_00997	2.2e-308	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
GKDNICOF_00998	2.81e-197	yvgN	-	-	C	-	-	-	Aldo keto reductase
GKDNICOF_01000	2.21e-172	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_01001	2.44e-97	-	-	-	K	-	-	-	acetyltransferase
GKDNICOF_01002	5.37e-64	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
GKDNICOF_01003	2.61e-150	-	-	-	S	-	-	-	Putative ABC-transporter type IV
GKDNICOF_01004	3.96e-154	-	-	-	M	-	-	-	LysM domain protein
GKDNICOF_01005	3.52e-144	-	-	-	M	-	-	-	LysM domain protein
GKDNICOF_01007	8.77e-77	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
GKDNICOF_01008	2.92e-235	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
GKDNICOF_01009	2.9e-71	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GKDNICOF_01010	3.22e-168	-	-	-	K	-	-	-	SIS domain
GKDNICOF_01011	3.87e-208	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
GKDNICOF_01014	3.98e-67	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
GKDNICOF_01015	9.35e-241	-	-	-	-	-	-	-	-
GKDNICOF_01016	5.19e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
GKDNICOF_01017	2.31e-87	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
GKDNICOF_01018	4.42e-165	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GKDNICOF_01019	2.46e-250	-	-	-	M	-	-	-	Glycosyl transferases group 1
GKDNICOF_01020	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
GKDNICOF_01021	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKDNICOF_01022	8.39e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GKDNICOF_01023	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GKDNICOF_01024	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
GKDNICOF_01025	1.01e-186	-	-	-	-	-	-	-	-
GKDNICOF_01026	6.91e-281	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GKDNICOF_01027	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
GKDNICOF_01028	3.03e-166	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
GKDNICOF_01029	6.18e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
GKDNICOF_01031	1.2e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
GKDNICOF_01032	8.45e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
GKDNICOF_01033	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
GKDNICOF_01034	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKDNICOF_01035	3.81e-264	camS	-	-	S	-	-	-	sex pheromone
GKDNICOF_01036	1.29e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKDNICOF_01037	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GKDNICOF_01038	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKDNICOF_01039	1.79e-213	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
GKDNICOF_01041	4.85e-191	-	-	-	S	-	-	-	hydrolase
GKDNICOF_01042	7.35e-173	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
GKDNICOF_01043	7.7e-166	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
GKDNICOF_01044	3.76e-236	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
GKDNICOF_01045	8.72e-70	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
GKDNICOF_01046	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKDNICOF_01047	3.6e-264	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GKDNICOF_01048	3.85e-237	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GKDNICOF_01050	0.0	-	-	-	UW	-	-	-	Tetratricopeptide repeat
GKDNICOF_01052	9.16e-110	-	-	-	M	-	-	-	family 8
GKDNICOF_01053	8.48e-117	-	-	-	M	-	-	-	family 8
GKDNICOF_01054	5.11e-279	-	-	-	M	-	-	-	family 8
GKDNICOF_01055	1.35e-139	-	-	-	S	-	-	-	glycosyl transferase family 2
GKDNICOF_01056	7.47e-194	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
GKDNICOF_01057	3.97e-119	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
GKDNICOF_01058	4.86e-113	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
GKDNICOF_01059	5.04e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
GKDNICOF_01060	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
GKDNICOF_01061	4.65e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
GKDNICOF_01062	1.59e-182	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
GKDNICOF_01063	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01064	1.04e-122	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
GKDNICOF_01065	3.07e-206	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
GKDNICOF_01066	2.12e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
GKDNICOF_01067	5.66e-167	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01068	8.51e-145	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
GKDNICOF_01069	9.24e-317	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKDNICOF_01070	4.78e-232	flp	-	-	V	-	-	-	Beta-lactamase
GKDNICOF_01071	3.03e-112	-	-	-	L	-	-	-	NUDIX domain
GKDNICOF_01072	4.67e-83	-	-	-	-	-	-	-	-
GKDNICOF_01073	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
GKDNICOF_01075	8.55e-189	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
GKDNICOF_01076	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
GKDNICOF_01077	1.29e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
GKDNICOF_01078	9.01e-276	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
GKDNICOF_01079	0.0	yhaN	-	-	L	-	-	-	AAA domain
GKDNICOF_01080	3.72e-238	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
GKDNICOF_01081	1.44e-201	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GKDNICOF_01082	2.65e-51	-	-	-	S	-	-	-	YtxH-like protein
GKDNICOF_01083	3.22e-83	-	-	-	-	-	-	-	-
GKDNICOF_01084	8.29e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
GKDNICOF_01085	8.97e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01086	1.85e-282	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
GKDNICOF_01087	1.07e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GKDNICOF_01088	2.09e-29	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_01091	2.53e-67	ytpP	-	-	CO	-	-	-	Thioredoxin
GKDNICOF_01092	1.77e-156	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKDNICOF_01093	4.96e-87	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
GKDNICOF_01094	1.28e-62	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
GKDNICOF_01095	3.35e-305	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
GKDNICOF_01096	2.47e-223	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
GKDNICOF_01097	1.83e-113	-	-	-	S	-	-	-	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
GKDNICOF_01098	9.63e-247	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKDNICOF_01099	1.8e-135	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
GKDNICOF_01100	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
GKDNICOF_01101	3.03e-122	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
GKDNICOF_01102	1.55e-161	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GKDNICOF_01103	8.83e-234	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
GKDNICOF_01104	8.24e-146	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
GKDNICOF_01105	1.59e-262	degS	2.7.13.3	-	F	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
GKDNICOF_01106	3.31e-186	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
GKDNICOF_01107	1.41e-88	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
GKDNICOF_01108	5.35e-123	levB	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GKDNICOF_01109	4.37e-183	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
GKDNICOF_01110	1.19e-192	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
GKDNICOF_01111	1.68e-61	-	-	-	-	-	-	-	-
GKDNICOF_01112	1.84e-80	-	-	-	K	-	-	-	Transcriptional regulator
GKDNICOF_01113	2.57e-274	-	-	-	EGP	-	-	-	Major Facilitator
GKDNICOF_01114	2.59e-277	dpaL	4.3.1.15	-	E	ko:K01751	-	ko00000,ko01000	Pyridoxal-phosphate dependent enzyme
GKDNICOF_01115	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKDNICOF_01116	2.42e-198	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GKDNICOF_01117	3.07e-135	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKDNICOF_01118	5.92e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKDNICOF_01119	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
GKDNICOF_01120	1.07e-208	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
GKDNICOF_01121	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKDNICOF_01122	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKDNICOF_01123	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
GKDNICOF_01124	3.54e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKDNICOF_01125	1.53e-221	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GKDNICOF_01126	3.44e-117	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
GKDNICOF_01127	4.38e-266	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
GKDNICOF_01128	1.16e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKDNICOF_01129	6.98e-137	yqeK	-	-	H	-	-	-	Hydrolase, HD family
GKDNICOF_01130	7.25e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GKDNICOF_01131	1.28e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
GKDNICOF_01132	1.61e-120	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
GKDNICOF_01133	3.11e-169	csrR	-	-	K	-	-	-	response regulator
GKDNICOF_01134	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GKDNICOF_01135	1.06e-213	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKDNICOF_01136	4.07e-57	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
GKDNICOF_01137	7.62e-170	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKDNICOF_01138	1.01e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GKDNICOF_01139	1.29e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKDNICOF_01140	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKDNICOF_01141	1.06e-259	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKDNICOF_01142	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKDNICOF_01143	0.0	-	-	-	S	-	-	-	membrane
GKDNICOF_01144	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GKDNICOF_01145	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GKDNICOF_01146	8.64e-106	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKDNICOF_01147	5.17e-151	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
GKDNICOF_01148	3.31e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
GKDNICOF_01149	4.22e-76	yqhL	-	-	P	-	-	-	Rhodanese-like protein
GKDNICOF_01150	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
GKDNICOF_01151	4.28e-203	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKDNICOF_01152	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
GKDNICOF_01153	6.81e-255	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GKDNICOF_01154	8.69e-189	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GKDNICOF_01156	1.85e-212	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
GKDNICOF_01157	4.94e-268	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
GKDNICOF_01158	6.44e-264	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
GKDNICOF_01159	2.37e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
GKDNICOF_01160	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKDNICOF_01161	8.48e-176	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
GKDNICOF_01162	2.13e-145	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
GKDNICOF_01163	3.1e-112	-	-	-	-	-	-	-	-
GKDNICOF_01164	2.82e-100	-	-	-	-	-	-	-	-
GKDNICOF_01165	6.39e-200	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
GKDNICOF_01166	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKDNICOF_01167	1.26e-58	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
GKDNICOF_01168	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
GKDNICOF_01169	4.33e-36	-	-	-	-	-	-	-	-
GKDNICOF_01170	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
GKDNICOF_01171	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKDNICOF_01172	5.79e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKDNICOF_01173	1.91e-152	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GKDNICOF_01174	3.13e-196	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
GKDNICOF_01175	1e-135	yjbH	-	-	Q	-	-	-	Thioredoxin
GKDNICOF_01176	4.87e-141	-	-	-	S	-	-	-	CYTH
GKDNICOF_01177	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
GKDNICOF_01178	2.24e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKDNICOF_01179	3.34e-212	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GKDNICOF_01180	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
GKDNICOF_01181	2.57e-282	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
GKDNICOF_01182	5.61e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
GKDNICOF_01183	6.3e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
GKDNICOF_01184	4.04e-265	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
GKDNICOF_01185	2.2e-134	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GKDNICOF_01186	1.13e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
GKDNICOF_01187	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
GKDNICOF_01188	2.33e-281	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
GKDNICOF_01189	4.03e-284	ymfH	-	-	S	-	-	-	Peptidase M16
GKDNICOF_01190	8.86e-159	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
GKDNICOF_01191	1.9e-164	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
GKDNICOF_01192	4.23e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKDNICOF_01193	3.49e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKDNICOF_01194	9.25e-311	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
GKDNICOF_01195	9.48e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
GKDNICOF_01196	1.75e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
GKDNICOF_01197	4.4e-289	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
GKDNICOF_01198	1.61e-147	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
GKDNICOF_01199	2.35e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKDNICOF_01200	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKDNICOF_01201	1.39e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKDNICOF_01202	6.23e-48	-	-	-	-	-	-	-	-
GKDNICOF_01203	1.17e-222	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKDNICOF_01204	3.3e-197	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKDNICOF_01205	1.48e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
GKDNICOF_01206	1.94e-217	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GKDNICOF_01207	1.67e-44	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_01208	4.51e-38	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
GKDNICOF_01209	4.35e-255	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKDNICOF_01210	1.33e-51	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GKDNICOF_01212	8.14e-239	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GKDNICOF_01213	3.48e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GKDNICOF_01214	1.86e-211	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKDNICOF_01215	5e-268	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GKDNICOF_01216	1.02e-283	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
GKDNICOF_01217	1.03e-26	-	-	-	-	-	-	-	-
GKDNICOF_01220	1.65e-29	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
GKDNICOF_01221	5.65e-67	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
GKDNICOF_01223	7.98e-87	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GKDNICOF_01224	9.02e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GKDNICOF_01225	3.6e-223	-	-	-	S	-	-	-	Acyltransferase family
GKDNICOF_01226	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
GKDNICOF_01227	3.39e-276	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
GKDNICOF_01228	8.91e-270	-	-	-	-	-	-	-	-
GKDNICOF_01229	2.53e-240	-	-	-	M	-	-	-	Glycosyl transferase family 2
GKDNICOF_01230	1.55e-251	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
GKDNICOF_01231	1.49e-252	-	-	-	M	-	-	-	Glycosyl transferases group 1
GKDNICOF_01232	2.38e-204	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
GKDNICOF_01233	7.2e-235	-	-	-	H	-	-	-	Glycosyl transferase family 11
GKDNICOF_01234	4.75e-158	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
GKDNICOF_01235	1.65e-112	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
GKDNICOF_01236	7e-108	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
GKDNICOF_01237	1.23e-149	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
GKDNICOF_01238	2.6e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
GKDNICOF_01239	7.42e-162	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
GKDNICOF_01240	2.15e-181	epsB	-	-	M	-	-	-	biosynthesis protein
GKDNICOF_01241	7.74e-215	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GKDNICOF_01242	5.83e-100	-	-	-	K	-	-	-	DNA-templated transcription, initiation
GKDNICOF_01243	2.84e-206	-	-	-	-	-	-	-	-
GKDNICOF_01244	1.54e-149	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
GKDNICOF_01245	1.67e-274	-	-	-	-	-	-	-	-
GKDNICOF_01246	8.46e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
GKDNICOF_01247	5.03e-105	-	-	-	-	-	-	-	-
GKDNICOF_01248	5.02e-110	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKDNICOF_01249	7.58e-134	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
GKDNICOF_01250	3.4e-294	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKDNICOF_01251	2.55e-278	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GKDNICOF_01252	2.86e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKDNICOF_01253	2.51e-200	-	-	-	-	-	-	-	-
GKDNICOF_01254	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKDNICOF_01255	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKDNICOF_01256	1.97e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
GKDNICOF_01257	3.62e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
GKDNICOF_01258	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
GKDNICOF_01259	3.72e-109	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
GKDNICOF_01260	5.34e-223	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
GKDNICOF_01261	6.22e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKDNICOF_01262	4.42e-118	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
GKDNICOF_01263	8.28e-64	ylbG	-	-	S	-	-	-	UPF0298 protein
GKDNICOF_01264	6.47e-267	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
GKDNICOF_01265	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
GKDNICOF_01266	2.79e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKDNICOF_01267	8.85e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
GKDNICOF_01268	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKDNICOF_01269	6.37e-207	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
GKDNICOF_01270	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GKDNICOF_01271	1.5e-143	-	-	-	S	-	-	-	repeat protein
GKDNICOF_01272	1.96e-56	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
GKDNICOF_01273	1.82e-88	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
GKDNICOF_01274	5.56e-274	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GKDNICOF_01275	1.8e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
GKDNICOF_01276	3.47e-266	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GKDNICOF_01277	1.14e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKDNICOF_01278	1.29e-25	-	-	-	-	-	-	-	-
GKDNICOF_01279	5.19e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
GKDNICOF_01280	6.55e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
GKDNICOF_01281	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKDNICOF_01282	7.62e-159	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
GKDNICOF_01283	2.65e-176	ylmH	-	-	S	-	-	-	S4 domain protein
GKDNICOF_01284	1.93e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
GKDNICOF_01285	1.49e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GKDNICOF_01286	5.53e-302	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKDNICOF_01287	5.8e-306	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GKDNICOF_01288	1.04e-190	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GKDNICOF_01289	3.06e-262	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKDNICOF_01290	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKDNICOF_01291	3.01e-225	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKDNICOF_01292	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GKDNICOF_01293	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
GKDNICOF_01294	3.13e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GKDNICOF_01295	1.55e-99	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
GKDNICOF_01296	1.81e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
GKDNICOF_01297	1.66e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
GKDNICOF_01298	1.9e-121	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
GKDNICOF_01299	1.67e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
GKDNICOF_01300	4.23e-223	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
GKDNICOF_01301	1.39e-141	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
GKDNICOF_01302	8.33e-156	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
GKDNICOF_01303	5.5e-283	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
GKDNICOF_01304	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GKDNICOF_01305	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GKDNICOF_01306	1.13e-235	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
GKDNICOF_01307	7.69e-140	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GKDNICOF_01308	6.03e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKDNICOF_01309	6.53e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GKDNICOF_01310	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKDNICOF_01312	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKDNICOF_01313	7.77e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
GKDNICOF_01314	2.15e-298	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
GKDNICOF_01315	5.27e-07	-	-	-	-	-	-	-	-
GKDNICOF_01316	2.26e-105	uspA	-	-	T	-	-	-	universal stress protein
GKDNICOF_01317	5.31e-284	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
GKDNICOF_01318	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
GKDNICOF_01319	2.74e-69	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
GKDNICOF_01320	2.09e-21	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
GKDNICOF_01321	5.85e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
GKDNICOF_01322	1.2e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
GKDNICOF_01323	2.1e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
GKDNICOF_01324	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKDNICOF_01325	2.86e-218	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKDNICOF_01326	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKDNICOF_01327	1.09e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKDNICOF_01328	1.25e-75	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKDNICOF_01329	9.31e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKDNICOF_01330	1.01e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
GKDNICOF_01331	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKDNICOF_01332	3.04e-236	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GKDNICOF_01333	6.38e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GKDNICOF_01334	2.56e-250	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKDNICOF_01335	2.75e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
GKDNICOF_01336	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
GKDNICOF_01337	2.42e-248	ampC	-	-	V	-	-	-	Beta-lactamase
GKDNICOF_01340	1.03e-85	-	-	-	-	-	-	-	-
GKDNICOF_01341	2.07e-276	-	-	-	EGP	-	-	-	Major Facilitator
GKDNICOF_01342	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
GKDNICOF_01343	1.46e-134	vanZ	-	-	V	-	-	-	VanZ like family
GKDNICOF_01344	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKDNICOF_01345	0.0	yclK	-	-	T	-	-	-	Histidine kinase
GKDNICOF_01346	6.34e-165	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
GKDNICOF_01347	6.62e-87	-	-	-	S	-	-	-	SdpI/YhfL protein family
GKDNICOF_01348	1.03e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
GKDNICOF_01349	4.4e-239	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
GKDNICOF_01350	5.55e-102	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
GKDNICOF_01351	8.68e-283	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
GKDNICOF_01354	4.21e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKDNICOF_01355	4.31e-232	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
GKDNICOF_01356	1.2e-106	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
GKDNICOF_01357	1.15e-85	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
GKDNICOF_01358	5.14e-52	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
GKDNICOF_01359	5.41e-216	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
GKDNICOF_01360	5.27e-209	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
GKDNICOF_01361	6.1e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
GKDNICOF_01362	9.17e-126	-	-	-	S	-	-	-	VanZ like family
GKDNICOF_01363	1.18e-261	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKDNICOF_01364	9.02e-200	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GKDNICOF_01365	2.13e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase family
GKDNICOF_01366	3.52e-141	-	-	-	-	-	-	-	-
GKDNICOF_01367	2.5e-230	-	-	-	S	-	-	-	Putative adhesin
GKDNICOF_01368	4.27e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKDNICOF_01369	8.02e-84	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKDNICOF_01370	3.09e-177	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GKDNICOF_01371	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKDNICOF_01372	3.49e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
GKDNICOF_01373	1.83e-196	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKDNICOF_01374	6.42e-262	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GKDNICOF_01375	5.35e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKDNICOF_01376	2.35e-177	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKDNICOF_01377	1.99e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GKDNICOF_01378	9.47e-209	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
GKDNICOF_01379	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GKDNICOF_01380	1.89e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
GKDNICOF_01381	3.94e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
GKDNICOF_01382	4.61e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKDNICOF_01383	2.14e-197	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GKDNICOF_01384	8.14e-120	-	-	-	-	-	-	-	-
GKDNICOF_01385	3.5e-132	-	-	-	-	-	-	-	-
GKDNICOF_01387	5.18e-134	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
GKDNICOF_01388	8.46e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GKDNICOF_01389	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GKDNICOF_01390	1.07e-39	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GKDNICOF_01391	1.18e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKDNICOF_01392	2.4e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKDNICOF_01393	1.42e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
GKDNICOF_01394	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKDNICOF_01395	1.02e-235	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
GKDNICOF_01397	0.0	ycaM	-	-	E	-	-	-	amino acid
GKDNICOF_01398	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GKDNICOF_01399	1.12e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
GKDNICOF_01400	1.88e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
GKDNICOF_01401	3.19e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
GKDNICOF_01402	4.11e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
GKDNICOF_01403	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GKDNICOF_01404	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GKDNICOF_01405	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GKDNICOF_01406	8.14e-239	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
GKDNICOF_01407	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
GKDNICOF_01408	2.93e-285	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKDNICOF_01409	2.1e-223	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
GKDNICOF_01411	8.96e-179	-	-	-	I	-	-	-	Acyl-transferase
GKDNICOF_01412	4.18e-198	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
GKDNICOF_01413	1.1e-228	-	-	-	M	-	-	-	Glycosyl transferase family 8
GKDNICOF_01414	3.38e-225	-	-	-	M	-	-	-	Glycosyl transferase family 8
GKDNICOF_01415	3.59e-205	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
GKDNICOF_01416	1.29e-299	-	-	-	P	-	-	-	Major Facilitator Superfamily
GKDNICOF_01417	3.3e-314	-	-	-	P	-	-	-	Major Facilitator Superfamily
GKDNICOF_01418	4.17e-235	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
GKDNICOF_01419	1.48e-118	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
GKDNICOF_01420	1.14e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GKDNICOF_01421	3.12e-161	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GKDNICOF_01422	3.35e-304	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GKDNICOF_01423	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
GKDNICOF_01424	2.44e-214	-	-	-	K	-	-	-	LysR substrate binding domain
GKDNICOF_01425	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
GKDNICOF_01426	0.0	-	-	-	M	-	-	-	domain protein
GKDNICOF_01427	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKDNICOF_01428	0.0	-	-	-	S	-	-	-	domain, Protein
GKDNICOF_01429	1.71e-246	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKDNICOF_01430	3.09e-127	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
GKDNICOF_01431	7.62e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKDNICOF_01432	5.4e-293	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
GKDNICOF_01433	1.52e-224	ydbI	-	-	K	-	-	-	AI-2E family transporter
GKDNICOF_01434	2.12e-53	-	-	-	-	-	-	-	-
GKDNICOF_01435	4.99e-196	-	-	-	S	-	-	-	Alpha beta hydrolase
GKDNICOF_01436	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
GKDNICOF_01437	2.96e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
GKDNICOF_01438	1.29e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
GKDNICOF_01439	1.84e-18	-	-	-	S	-	-	-	CsbD-like
GKDNICOF_01440	3.41e-205	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
GKDNICOF_01441	0.0	fusA1	-	-	J	-	-	-	elongation factor G
GKDNICOF_01442	7.84e-26	-	-	-	-	-	-	-	-
GKDNICOF_01443	2.31e-193	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
GKDNICOF_01444	8.76e-176	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
GKDNICOF_01445	1.28e-167	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
GKDNICOF_01446	6.87e-145	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
GKDNICOF_01447	3.39e-256	-	-	-	S	-	-	-	Sterol carrier protein domain
GKDNICOF_01449	1.11e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
GKDNICOF_01450	4e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
GKDNICOF_01451	4.18e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
GKDNICOF_01452	5.26e-141	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
GKDNICOF_01454	2.08e-148	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
GKDNICOF_01455	0.0	-	-	-	-	-	-	-	-
GKDNICOF_01456	3.01e-274	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
GKDNICOF_01457	1e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
GKDNICOF_01458	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
GKDNICOF_01459	1.58e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GKDNICOF_01460	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
GKDNICOF_01461	3.9e-214	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
GKDNICOF_01462	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKDNICOF_01463	7.47e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKDNICOF_01464	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
GKDNICOF_01465	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKDNICOF_01466	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKDNICOF_01467	8.09e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKDNICOF_01468	1.04e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
GKDNICOF_01469	2.32e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKDNICOF_01470	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKDNICOF_01471	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
GKDNICOF_01472	3.62e-79	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GKDNICOF_01473	9.81e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKDNICOF_01474	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKDNICOF_01475	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GKDNICOF_01476	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
GKDNICOF_01477	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKDNICOF_01478	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GKDNICOF_01479	1.97e-135	pncA	-	-	Q	-	-	-	Isochorismatase family
GKDNICOF_01480	4.57e-259	-	-	-	EGP	-	-	-	Major facilitator Superfamily
GKDNICOF_01481	1.73e-193	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
GKDNICOF_01482	3.26e-135	-	-	-	-	-	-	-	-
GKDNICOF_01483	4.21e-149	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
GKDNICOF_01484	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKDNICOF_01485	1.87e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
GKDNICOF_01486	8.8e-301	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
GKDNICOF_01487	2.35e-91	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GKDNICOF_01488	2.46e-308	ynbB	-	-	P	-	-	-	aluminum resistance
GKDNICOF_01489	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
GKDNICOF_01490	0.0	-	-	-	E	-	-	-	Amino acid permease
GKDNICOF_01491	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
GKDNICOF_01492	1.24e-181	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
GKDNICOF_01493	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
GKDNICOF_01494	1.23e-62	-	-	-	S	-	-	-	Cupredoxin-like domain
GKDNICOF_01495	1.77e-85	-	-	-	S	-	-	-	Cupredoxin-like domain
GKDNICOF_01496	3.09e-102	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
GKDNICOF_01497	7.74e-107	-	-	-	-	-	-	-	-
GKDNICOF_01498	5.64e-100	-	-	-	-	-	-	-	-
GKDNICOF_01499	1.07e-96	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
GKDNICOF_01500	1.37e-277	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
GKDNICOF_01501	3.21e-242	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_01502	1.22e-165	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKDNICOF_01503	1.64e-89	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
GKDNICOF_01504	1.01e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GKDNICOF_01505	4.54e-60	-	-	-	I	-	-	-	bis(5'-adenosyl)-triphosphatase activity
GKDNICOF_01506	5.76e-296	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GKDNICOF_01507	3.38e-118	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GKDNICOF_01509	1.55e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GKDNICOF_01510	5.44e-299	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
GKDNICOF_01511	2.4e-161	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
GKDNICOF_01512	4.16e-153	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
GKDNICOF_01513	1.26e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKDNICOF_01514	2.6e-126	-	-	-	S	-	-	-	Aldo/keto reductase family
GKDNICOF_01515	2.34e-62	-	-	-	S	-	-	-	Aldo/keto reductase family
GKDNICOF_01516	1.28e-89	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_01517	1.54e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GKDNICOF_01518	7.59e-192	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKDNICOF_01519	7.21e-154	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
GKDNICOF_01520	2.49e-237	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
GKDNICOF_01521	8.49e-111	XK27_11925	-	-	V	-	-	-	Beta-lactamase
GKDNICOF_01522	8.11e-69	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GKDNICOF_01523	3.44e-152	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
GKDNICOF_01524	1.38e-127	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
GKDNICOF_01525	4.74e-217	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
GKDNICOF_01526	2.93e-215	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GKDNICOF_01527	3.44e-241	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
GKDNICOF_01528	2.01e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
GKDNICOF_01529	2.64e-308	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
GKDNICOF_01533	2.47e-223	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
GKDNICOF_01534	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GKDNICOF_01535	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GKDNICOF_01536	1.18e-228	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
GKDNICOF_01537	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
GKDNICOF_01538	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01539	3.19e-245	-	-	-	S	-	-	-	DUF218 domain
GKDNICOF_01540	9.21e-134	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GKDNICOF_01541	2.84e-117	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
GKDNICOF_01542	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
GKDNICOF_01543	2.1e-290	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
GKDNICOF_01544	1.12e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
GKDNICOF_01545	4.79e-200	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
GKDNICOF_01546	9.45e-152	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GKDNICOF_01547	4.78e-42	-	-	-	-	-	-	-	-
GKDNICOF_01548	3.71e-167	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
GKDNICOF_01549	1.97e-201	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GKDNICOF_01550	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
GKDNICOF_01551	4.76e-74	-	-	-	S	-	-	-	Putative adhesin
GKDNICOF_01552	6.29e-254	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
GKDNICOF_01553	0.0	cadA	-	-	P	-	-	-	P-type ATPase
GKDNICOF_01554	7.94e-109	ykuL	-	-	S	-	-	-	(CBS) domain
GKDNICOF_01557	3.67e-256	-	-	-	S	-	-	-	Membrane
GKDNICOF_01558	3.97e-59	-	-	-	-	-	-	-	-
GKDNICOF_01559	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
GKDNICOF_01560	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKDNICOF_01561	2.61e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
GKDNICOF_01562	3.63e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKDNICOF_01563	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKDNICOF_01564	1.37e-220	pbpX2	-	-	V	-	-	-	Beta-lactamase
GKDNICOF_01565	2.93e-272	-	-	-	E	-	-	-	Major Facilitator Superfamily
GKDNICOF_01566	1.74e-52	-	-	-	-	-	-	-	-
GKDNICOF_01567	2.01e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKDNICOF_01568	2.23e-166	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GKDNICOF_01569	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
GKDNICOF_01570	1.79e-316	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
GKDNICOF_01571	3.23e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKDNICOF_01572	4.39e-209	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
GKDNICOF_01573	1.13e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
GKDNICOF_01574	1.74e-308	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKDNICOF_01575	4.36e-105	-	-	-	L	-	-	-	MgsA AAA+ ATPase C terminal
GKDNICOF_01576	2.8e-159	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GKDNICOF_01577	3.14e-167	-	-	-	S	-	-	-	Peptidase_C39 like family
GKDNICOF_01579	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
GKDNICOF_01580	4.34e-152	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
GKDNICOF_01582	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
GKDNICOF_01583	9.56e-178	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GKDNICOF_01584	1.14e-164	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GKDNICOF_01585	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GKDNICOF_01586	2.24e-184	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
GKDNICOF_01587	3.89e-68	-	-	-	-	-	-	-	-
GKDNICOF_01588	8.21e-33	-	-	-	-	-	-	-	-
GKDNICOF_01589	5.49e-156	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
GKDNICOF_01590	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
GKDNICOF_01591	7.37e-170	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01592	0.0	-	-	-	E	-	-	-	Amino Acid
GKDNICOF_01593	3.4e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKDNICOF_01594	2.31e-286	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
GKDNICOF_01595	2.55e-156	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
GKDNICOF_01596	2.78e-125	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
GKDNICOF_01597	3.52e-58	-	-	-	-	-	-	-	-
GKDNICOF_01598	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
GKDNICOF_01599	7.47e-141	-	-	-	-	-	-	-	-
GKDNICOF_01600	2.61e-105	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
GKDNICOF_01601	1.16e-221	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKDNICOF_01602	6.23e-102	-	-	-	-	-	-	-	-
GKDNICOF_01603	8.86e-78	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
GKDNICOF_01604	1.75e-52	-	-	-	-	-	-	-	-
GKDNICOF_01605	1.1e-103	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
GKDNICOF_01606	6.3e-177	-	-	-	S	-	-	-	Putative threonine/serine exporter
GKDNICOF_01607	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
GKDNICOF_01608	6.28e-78	-	-	-	-	-	-	-	-
GKDNICOF_01609	5.23e-50	-	-	-	-	-	-	-	-
GKDNICOF_01610	1.42e-269	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GKDNICOF_01611	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
GKDNICOF_01612	5.12e-88	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_01613	2.25e-05	-	-	-	D	-	-	-	nuclear chromosome segregation
GKDNICOF_01614	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
GKDNICOF_01615	1.11e-167	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
GKDNICOF_01616	5.02e-149	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GKDNICOF_01617	1.6e-203	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GKDNICOF_01618	4.8e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
GKDNICOF_01619	1.3e-175	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
GKDNICOF_01620	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GKDNICOF_01621	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
GKDNICOF_01622	1.21e-212	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GKDNICOF_01623	6.31e-173	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
GKDNICOF_01624	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
GKDNICOF_01625	6.26e-259	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
GKDNICOF_01626	3.17e-205	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01627	3.05e-183	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
GKDNICOF_01628	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKDNICOF_01629	5.3e-264	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
GKDNICOF_01630	2.39e-156	vanR	-	-	K	-	-	-	response regulator
GKDNICOF_01631	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
GKDNICOF_01632	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01633	1.33e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
GKDNICOF_01634	2.68e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GKDNICOF_01635	2.12e-57	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
GKDNICOF_01636	9.01e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GKDNICOF_01637	3.52e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
GKDNICOF_01638	1.95e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GKDNICOF_01639	1.27e-161	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
GKDNICOF_01640	3.03e-123	cvpA	-	-	S	-	-	-	Colicin V production protein
GKDNICOF_01641	9e-226	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GKDNICOF_01642	1.62e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GKDNICOF_01643	2.03e-248	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
GKDNICOF_01644	2.12e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
GKDNICOF_01645	5.44e-127	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
GKDNICOF_01646	1.4e-140	-	-	-	K	-	-	-	WHG domain
GKDNICOF_01647	6.73e-51	-	-	-	-	-	-	-	-
GKDNICOF_01648	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GKDNICOF_01649	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GKDNICOF_01650	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GKDNICOF_01651	2.07e-202	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
GKDNICOF_01652	1.79e-145	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01653	3.11e-229	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
GKDNICOF_01654	2.12e-51	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GKDNICOF_01655	2.75e-53	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GKDNICOF_01656	1.03e-138	-	-	-	G	-	-	-	phosphoglycerate mutase
GKDNICOF_01657	3.86e-143	-	-	-	G	-	-	-	Phosphoglycerate mutase family
GKDNICOF_01658	2.33e-176	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
GKDNICOF_01659	1.15e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
GKDNICOF_01660	9.53e-169	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
GKDNICOF_01661	4.81e-69	-	-	-	-	-	-	-	-
GKDNICOF_01662	2.8e-160	-	-	-	-	-	-	-	-
GKDNICOF_01663	2.59e-200	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GKDNICOF_01664	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
GKDNICOF_01665	1.82e-177	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
GKDNICOF_01666	9.8e-197	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GKDNICOF_01667	2.97e-210	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
GKDNICOF_01668	7.45e-67	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
GKDNICOF_01669	4.82e-199	-	-	-	-	-	-	-	-
GKDNICOF_01670	8.48e-284	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
GKDNICOF_01671	2.21e-156	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
GKDNICOF_01672	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
GKDNICOF_01673	1.47e-116	ymdB	-	-	S	-	-	-	Macro domain protein
GKDNICOF_01674	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GKDNICOF_01675	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
GKDNICOF_01676	2.81e-235	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
GKDNICOF_01677	7.98e-65	-	-	-	G	-	-	-	polysaccharide catabolic process
GKDNICOF_01678	1.08e-73	ptsD	-	-	G	ko:K02796,ko:K19509	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
GKDNICOF_01679	3.6e-46	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
GKDNICOF_01680	3.34e-41	-	-	-	G	-	-	-	PTS system sorbose subfamily IIB component
GKDNICOF_01681	4.07e-28	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
GKDNICOF_01682	5.14e-238	-	-	-	K	-	-	-	Sigma-54 interaction domain
GKDNICOF_01683	2.42e-39	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
GKDNICOF_01684	1.57e-185	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GKDNICOF_01685	1.26e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GKDNICOF_01686	5.7e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
GKDNICOF_01687	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
GKDNICOF_01688	1.52e-207	-	-	-	EG	-	-	-	EamA-like transporter family
GKDNICOF_01689	1.61e-244	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
GKDNICOF_01690	2.55e-270	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GKDNICOF_01691	2.71e-300	-	-	-	E	-	-	-	amino acid
GKDNICOF_01692	7.74e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
GKDNICOF_01693	1.52e-290	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
GKDNICOF_01694	8.98e-317	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
GKDNICOF_01695	6.05e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
GKDNICOF_01696	2.46e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
GKDNICOF_01697	1.75e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
GKDNICOF_01698	7.19e-235	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GKDNICOF_01699	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKDNICOF_01700	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
GKDNICOF_01701	1.39e-36	-	-	-	-	-	-	-	-
GKDNICOF_01702	2.8e-148	-	-	-	-	-	-	-	-
GKDNICOF_01703	1.24e-94	-	-	-	-	-	-	-	-
GKDNICOF_01704	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
GKDNICOF_01705	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
GKDNICOF_01706	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
GKDNICOF_01708	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
GKDNICOF_01709	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
GKDNICOF_01711	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKDNICOF_01712	2.8e-204	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
GKDNICOF_01713	3.29e-173	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GKDNICOF_01714	5.5e-275	-	-	-	D	-	-	-	transport
GKDNICOF_01715	1.56e-236	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
GKDNICOF_01716	8.53e-288	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
GKDNICOF_01717	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKDNICOF_01718	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKDNICOF_01719	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GKDNICOF_01720	2.7e-277	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
GKDNICOF_01721	1.24e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GKDNICOF_01722	6.16e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKDNICOF_01723	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
GKDNICOF_01724	6.6e-83	-	-	-	-	-	-	-	-
GKDNICOF_01725	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
GKDNICOF_01726	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
GKDNICOF_01727	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GKDNICOF_01728	6.97e-107	-	-	-	-	-	-	-	-
GKDNICOF_01729	1.23e-188	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GKDNICOF_01730	2.46e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GKDNICOF_01731	2.12e-180	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GKDNICOF_01732	1.59e-215	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
GKDNICOF_01734	1.66e-111	usp5	-	-	T	-	-	-	universal stress protein
GKDNICOF_01735	1.76e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GKDNICOF_01736	3.2e-156	-	-	-	K	-	-	-	UTRA domain
GKDNICOF_01737	1.62e-126	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKDNICOF_01738	2.21e-113	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
GKDNICOF_01739	7.46e-220	-	-	-	-	-	-	-	-
GKDNICOF_01740	4.7e-222	-	-	-	S	-	-	-	zinc-ribbon domain
GKDNICOF_01741	4.95e-19	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_01742	1.6e-89	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
GKDNICOF_01743	6.12e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
GKDNICOF_01744	1.87e-196	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
GKDNICOF_01745	3.23e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GKDNICOF_01746	7.27e-289	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKDNICOF_01747	1.48e-269	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
GKDNICOF_01748	1.22e-159	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
GKDNICOF_01749	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
GKDNICOF_01750	2.22e-192	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GKDNICOF_01751	3.63e-152	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
GKDNICOF_01752	1.23e-233	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
GKDNICOF_01753	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GKDNICOF_01754	8.62e-144	-	-	-	-	-	-	-	-
GKDNICOF_01755	1.05e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
GKDNICOF_01756	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
GKDNICOF_01757	4.69e-177	-	-	-	-	-	-	-	-
GKDNICOF_01758	1.38e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GKDNICOF_01759	3.22e-304	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GKDNICOF_01760	3.46e-43	-	-	-	S	-	-	-	CAAX protease self-immunity
GKDNICOF_01761	2.41e-202	-	-	-	S	-	-	-	CAAX protease self-immunity
GKDNICOF_01762	9e-230	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKDNICOF_01763	1.74e-76	-	-	-	-	-	-	-	-
GKDNICOF_01764	1.63e-159	-	-	-	S	-	-	-	Alpha/beta hydrolase family
GKDNICOF_01765	2.63e-202	-	-	-	M	-	-	-	Glycosyltransferase like family 2
GKDNICOF_01766	4.55e-217	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
GKDNICOF_01767	3.14e-177	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKDNICOF_01768	3.79e-220	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GKDNICOF_01769	8.59e-158	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
GKDNICOF_01770	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKDNICOF_01771	7.71e-104	-	-	-	-	-	-	-	-
GKDNICOF_01772	1.5e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
GKDNICOF_01773	5.26e-123	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
GKDNICOF_01774	7.22e-167	terC	-	-	P	-	-	-	Integral membrane protein TerC family
GKDNICOF_01775	1.23e-83	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
GKDNICOF_01776	4.84e-137	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
GKDNICOF_01777	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GKDNICOF_01778	1.22e-175	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01779	4.56e-215	-	-	-	L	-	-	-	HNH nucleases
GKDNICOF_01780	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
GKDNICOF_01781	2.27e-249	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
GKDNICOF_01782	1.47e-302	-	-	-	M	-	-	-	Glycosyl transferase
GKDNICOF_01784	9.55e-185	-	-	-	-	-	-	-	-
GKDNICOF_01785	1.14e-23	-	-	-	-	-	-	-	-
GKDNICOF_01786	1.78e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
GKDNICOF_01787	2.31e-240	ysdE	-	-	P	-	-	-	Citrate transporter
GKDNICOF_01788	1.8e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
GKDNICOF_01789	2.25e-188	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
GKDNICOF_01790	1.06e-204	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GKDNICOF_01791	1.18e-121	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
GKDNICOF_01792	6.85e-295	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GKDNICOF_01793	1.7e-130	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
GKDNICOF_01794	4.28e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKDNICOF_01795	1.29e-257	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
GKDNICOF_01796	1.45e-189	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
GKDNICOF_01797	4.1e-184	yycI	-	-	S	-	-	-	YycH protein
GKDNICOF_01798	7.46e-312	yycH	-	-	S	-	-	-	YycH protein
GKDNICOF_01799	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GKDNICOF_01800	3.03e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
GKDNICOF_01801	6.19e-300	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKDNICOF_01802	1.18e-125	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GKDNICOF_01803	4.21e-138	-	-	-	S	-	-	-	SNARE associated Golgi protein
GKDNICOF_01804	2.49e-184	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GKDNICOF_01805	5.77e-183	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
GKDNICOF_01806	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
GKDNICOF_01807	6.5e-224	-	-	-	-	-	-	-	-
GKDNICOF_01808	7.32e-156	-	-	-	S	-	-	-	SNARE associated Golgi protein
GKDNICOF_01809	5.84e-158	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GKDNICOF_01810	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
GKDNICOF_01811	1.16e-123	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GKDNICOF_01812	2.3e-206	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
GKDNICOF_01813	1.59e-214	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
GKDNICOF_01814	1.08e-96	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
GKDNICOF_01815	1.05e-107	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
GKDNICOF_01816	1.06e-90	yybA	-	-	K	-	-	-	Transcriptional regulator
GKDNICOF_01817	6.5e-73	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
GKDNICOF_01818	3.12e-308	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
GKDNICOF_01819	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
GKDNICOF_01820	2.79e-188	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GKDNICOF_01821	2.51e-201	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
GKDNICOF_01822	8.06e-258	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
GKDNICOF_01823	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GKDNICOF_01824	5.24e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
GKDNICOF_01825	1.01e-189	dkgB	-	-	S	-	-	-	reductase
GKDNICOF_01826	1.95e-251	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
GKDNICOF_01827	3.69e-231	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
GKDNICOF_01828	3.25e-181	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GKDNICOF_01829	4.85e-143	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
GKDNICOF_01830	3.73e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
GKDNICOF_01831	6.17e-299	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
GKDNICOF_01832	2.77e-110	-	-	-	S	-	-	-	PAS domain
GKDNICOF_01833	1.4e-187	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
GKDNICOF_01834	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GKDNICOF_01835	6.4e-70	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GKDNICOF_01836	2.75e-53	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GKDNICOF_01837	1.05e-165	-	-	-	S	-	-	-	PAS domain
GKDNICOF_01838	1.74e-310	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKDNICOF_01839	1.16e-264	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
GKDNICOF_01840	3.63e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GKDNICOF_01841	5.59e-78	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
GKDNICOF_01842	7.45e-222	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
GKDNICOF_01843	8.39e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
GKDNICOF_01844	4.27e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
GKDNICOF_01845	1.34e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GKDNICOF_01846	3.97e-125	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
GKDNICOF_01847	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GKDNICOF_01848	3.99e-74	-	-	-	-	-	-	-	-
GKDNICOF_01849	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
GKDNICOF_01850	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
GKDNICOF_01851	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
GKDNICOF_01852	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
GKDNICOF_01853	6.06e-221	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
GKDNICOF_01854	7.31e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GKDNICOF_01855	1.47e-67	-	-	-	-	-	-	-	-
GKDNICOF_01856	2.21e-34	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKDNICOF_01857	2.39e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
GKDNICOF_01858	4.15e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKDNICOF_01859	5.51e-147	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKDNICOF_01860	9.62e-179	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
GKDNICOF_01861	2.57e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
GKDNICOF_01862	6.29e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
GKDNICOF_01863	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKDNICOF_01864	4.44e-117	cvpA	-	-	S	-	-	-	Colicin V production protein
GKDNICOF_01865	5.16e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
GKDNICOF_01866	1.43e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKDNICOF_01867	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
GKDNICOF_01868	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKDNICOF_01869	2.03e-294	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GKDNICOF_01870	6.98e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
GKDNICOF_01871	8.73e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKDNICOF_01872	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKDNICOF_01873	9.39e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GKDNICOF_01874	5.49e-238	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GKDNICOF_01875	2.44e-129	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GKDNICOF_01876	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKDNICOF_01877	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKDNICOF_01878	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
GKDNICOF_01879	2.22e-279	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein