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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
CMHMHKIO_00001	6.79e-295	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
CMHMHKIO_00002	1.09e-220	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
CMHMHKIO_00003	9.82e-111	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
CMHMHKIO_00005	5.18e-104	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
CMHMHKIO_00006	1.53e-19	-	-	-	-	-	-	-	-
CMHMHKIO_00007	9.73e-275	yttB	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_00008	4.36e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CMHMHKIO_00009	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CMHMHKIO_00012	2.58e-166	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
CMHMHKIO_00013	6.41e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_00014	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_00015	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CMHMHKIO_00016	1.29e-181	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CMHMHKIO_00017	8.21e-212	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
CMHMHKIO_00018	9.13e-252	ampC	-	-	V	-	-	-	Beta-lactamase
CMHMHKIO_00019	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
CMHMHKIO_00020	7.61e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
CMHMHKIO_00021	8.62e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMHMHKIO_00022	2.32e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CMHMHKIO_00023	1.2e-238	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CMHMHKIO_00024	1.57e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMHMHKIO_00025	3.05e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CMHMHKIO_00026	1.23e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
CMHMHKIO_00027	2.57e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMHMHKIO_00028	1.13e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMHMHKIO_00029	3.37e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMHMHKIO_00030	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMHMHKIO_00031	1.92e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMHMHKIO_00032	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMHMHKIO_00033	1.88e-91	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
CMHMHKIO_00034	8.38e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
CMHMHKIO_00035	4.12e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
CMHMHKIO_00036	1.37e-26	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
CMHMHKIO_00037	1.14e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
CMHMHKIO_00038	8.37e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
CMHMHKIO_00039	1.41e-285	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
CMHMHKIO_00040	4.19e-65	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
CMHMHKIO_00041	3.19e-284	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CMHMHKIO_00042	1.88e-186	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CMHMHKIO_00043	8.04e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CMHMHKIO_00044	2.09e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMHMHKIO_00045	9.25e-150	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_00046	4.15e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
CMHMHKIO_00047	4.72e-244	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
CMHMHKIO_00048	6.46e-285	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CMHMHKIO_00049	1.72e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
CMHMHKIO_00050	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
CMHMHKIO_00051	4.73e-31	-	-	-	-	-	-	-	-
CMHMHKIO_00052	9.85e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CMHMHKIO_00053	3.03e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
CMHMHKIO_00054	1.29e-150	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
CMHMHKIO_00055	2.7e-200	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMHMHKIO_00056	2.86e-108	uspA	-	-	T	-	-	-	universal stress protein
CMHMHKIO_00057	9.94e-54	-	-	-	-	-	-	-	-
CMHMHKIO_00059	1.66e-306	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CMHMHKIO_00060	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
CMHMHKIO_00061	1.17e-100	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CMHMHKIO_00062	5.99e-143	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
CMHMHKIO_00063	1.02e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
CMHMHKIO_00064	1.61e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CMHMHKIO_00065	4.65e-158	-	-	-	G	-	-	-	alpha-ribazole phosphatase activity
CMHMHKIO_00066	7.23e-200	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMHMHKIO_00067	1.81e-222	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
CMHMHKIO_00068	2.93e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
CMHMHKIO_00069	2.05e-173	-	-	-	F	-	-	-	deoxynucleoside kinase
CMHMHKIO_00070	4.04e-203	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
CMHMHKIO_00071	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMHMHKIO_00072	1.24e-202	-	-	-	T	-	-	-	GHKL domain
CMHMHKIO_00073	2.69e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
CMHMHKIO_00074	1.17e-217	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CMHMHKIO_00075	4.43e-143	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMHMHKIO_00076	1.46e-207	-	-	-	K	-	-	-	Transcriptional regulator
CMHMHKIO_00077	9.46e-103	yphH	-	-	S	-	-	-	Cupin domain
CMHMHKIO_00078	1.07e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
CMHMHKIO_00079	2.72e-149	-	-	-	GM	-	-	-	NAD(P)H-binding
CMHMHKIO_00080	1.94e-54	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMHMHKIO_00081	4.73e-158	gst	2.5.1.18	-	O	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	ko00000,ko00001,ko01000,ko02000	Glutathione S-transferase, C-terminal domain
CMHMHKIO_00082	2.07e-149	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
CMHMHKIO_00083	7.95e-219	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_00084	3.03e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_00085	5.91e-199	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
CMHMHKIO_00086	2.07e-135	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
CMHMHKIO_00087	2.43e-264	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMHMHKIO_00088	1.17e-169	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
CMHMHKIO_00089	4.87e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_00090	1.07e-281	-	-	-	-	-	-	-	-
CMHMHKIO_00091	6.49e-90	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMHMHKIO_00092	4.87e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
CMHMHKIO_00093	4.9e-151	-	-	-	S	-	-	-	Protein of unknown function C-terminus (DUF2399)
CMHMHKIO_00094	5.07e-157	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_00095	1.23e-57	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CMHMHKIO_00096	8.76e-63	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
CMHMHKIO_00098	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
CMHMHKIO_00099	0.0	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CMHMHKIO_00100	5.05e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
CMHMHKIO_00101	1.12e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
CMHMHKIO_00102	4.22e-273	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
CMHMHKIO_00103	1.15e-150	yjbH	-	-	Q	-	-	-	Thioredoxin
CMHMHKIO_00104	1.79e-138	-	-	-	S	-	-	-	CYTH
CMHMHKIO_00105	1.19e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
CMHMHKIO_00106	1.05e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMHMHKIO_00107	1.22e-219	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CMHMHKIO_00108	4.86e-259	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMHMHKIO_00109	2.24e-148	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
CMHMHKIO_00110	2.39e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CMHMHKIO_00111	2.39e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
CMHMHKIO_00112	3.87e-80	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
CMHMHKIO_00113	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMHMHKIO_00114	2.45e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMHMHKIO_00115	1.94e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
CMHMHKIO_00116	1.46e-201	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
CMHMHKIO_00117	3.21e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CMHMHKIO_00118	4.04e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
CMHMHKIO_00119	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CMHMHKIO_00120	3.28e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
CMHMHKIO_00121	4.8e-310	ymfH	-	-	S	-	-	-	Peptidase M16
CMHMHKIO_00122	3.01e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
CMHMHKIO_00123	1.15e-169	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
CMHMHKIO_00124	3.46e-136	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMHMHKIO_00125	3.67e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
CMHMHKIO_00126	5.55e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMHMHKIO_00127	7.95e-317	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
CMHMHKIO_00128	5.06e-152	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
CMHMHKIO_00129	1.47e-304	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
CMHMHKIO_00130	4.32e-104	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
CMHMHKIO_00131	3.24e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMHMHKIO_00132	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMHMHKIO_00133	8.69e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMHMHKIO_00134	1.56e-161	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
CMHMHKIO_00135	1.9e-200	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CMHMHKIO_00136	7.77e-259	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
CMHMHKIO_00137	1.83e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CMHMHKIO_00138	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMHMHKIO_00139	4.5e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CMHMHKIO_00140	4.48e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CMHMHKIO_00141	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
CMHMHKIO_00142	1.57e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMHMHKIO_00143	2.49e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMHMHKIO_00144	3.82e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
CMHMHKIO_00145	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
CMHMHKIO_00146	5.23e-50	-	-	-	-	-	-	-	-
CMHMHKIO_00147	3.07e-50	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
CMHMHKIO_00148	8.27e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CMHMHKIO_00149	7.94e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMHMHKIO_00150	6.29e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
CMHMHKIO_00151	3.41e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMHMHKIO_00152	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CMHMHKIO_00153	1.51e-148	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
CMHMHKIO_00154	4.14e-225	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
CMHMHKIO_00155	8.85e-47	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
CMHMHKIO_00156	2.03e-96	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_00157	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CMHMHKIO_00158	1.99e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
CMHMHKIO_00159	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CMHMHKIO_00160	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CMHMHKIO_00161	2.56e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
CMHMHKIO_00162	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
CMHMHKIO_00163	2.99e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
CMHMHKIO_00164	2.88e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
CMHMHKIO_00165	7.84e-106	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
CMHMHKIO_00166	5.97e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMHMHKIO_00168	8.72e-280	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMHMHKIO_00169	2.5e-184	-	-	-	-	-	-	-	-
CMHMHKIO_00170	9.85e-49	-	-	-	-	-	-	-	-
CMHMHKIO_00171	5.99e-154	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
CMHMHKIO_00172	3.75e-98	-	-	-	E	-	-	-	Zn peptidase
CMHMHKIO_00173	1.9e-72	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMHMHKIO_00175	1.39e-183	-	-	-	K	-	-	-	ORF6N domain
CMHMHKIO_00176	4.68e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
CMHMHKIO_00182	6.5e-109	-	-	-	S	-	-	-	Siphovirus Gp157
CMHMHKIO_00184	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
CMHMHKIO_00185	1.89e-171	-	-	-	L	-	-	-	AAA domain
CMHMHKIO_00186	4.92e-120	-	-	-	-	-	-	-	-
CMHMHKIO_00187	6.41e-193	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
CMHMHKIO_00188	1.59e-302	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
CMHMHKIO_00189	1.66e-71	-	-	-	S	-	-	-	VRR_NUC
CMHMHKIO_00190	5.25e-59	-	-	-	-	-	-	-	-
CMHMHKIO_00192	7.3e-137	-	-	-	S	-	-	-	HNH endonuclease
CMHMHKIO_00194	2.86e-93	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
CMHMHKIO_00195	2.61e-92	-	-	-	V	-	-	-	HNH endonuclease
CMHMHKIO_00196	1.73e-83	-	-	-	-	-	-	-	-
CMHMHKIO_00197	7.23e-244	ysdE	-	-	P	-	-	-	Citrate transporter
CMHMHKIO_00198	3.35e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
CMHMHKIO_00199	8.39e-21	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
CMHMHKIO_00200	7.48e-197	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CMHMHKIO_00201	4.68e-189	-	-	-	-	-	-	-	-
CMHMHKIO_00202	1.38e-274	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
CMHMHKIO_00203	6.84e-186	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
CMHMHKIO_00204	8.58e-159	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_00205	6.3e-42	-	-	-	-	-	-	-	-
CMHMHKIO_00206	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CMHMHKIO_00207	1.14e-151	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMHMHKIO_00208	4.24e-226	-	-	-	S	-	-	-	Cell surface protein
CMHMHKIO_00209	1.78e-58	-	-	-	-	-	-	-	-
CMHMHKIO_00210	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CMHMHKIO_00211	1.66e-154	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMHMHKIO_00212	4.82e-78	-	-	-	-	-	-	-	-
CMHMHKIO_00213	3.82e-142	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
CMHMHKIO_00214	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CMHMHKIO_00215	4.19e-226	yicL	-	-	EG	-	-	-	EamA-like transporter family
CMHMHKIO_00216	0.0	-	-	-	-	-	-	-	-
CMHMHKIO_00217	3.03e-186	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_00218	4.07e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
CMHMHKIO_00219	1.83e-192	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
CMHMHKIO_00220	7.88e-211	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
CMHMHKIO_00221	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CMHMHKIO_00222	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_00223	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_00224	3.34e-286	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
CMHMHKIO_00225	5.43e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
CMHMHKIO_00226	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CMHMHKIO_00227	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMHMHKIO_00228	2.25e-285	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CMHMHKIO_00229	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
CMHMHKIO_00230	3.94e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
CMHMHKIO_00231	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
CMHMHKIO_00232	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
CMHMHKIO_00233	1.54e-91	-	-	-	-	-	-	-	-
CMHMHKIO_00234	1.37e-99	-	-	-	O	-	-	-	OsmC-like protein
CMHMHKIO_00235	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
CMHMHKIO_00236	2.73e-147	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
CMHMHKIO_00238	4.04e-204	-	-	-	S	-	-	-	Aldo/keto reductase family
CMHMHKIO_00239	9.04e-317	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
CMHMHKIO_00240	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
CMHMHKIO_00241	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CMHMHKIO_00242	2.72e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
CMHMHKIO_00243	2.95e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
CMHMHKIO_00244	3.79e-192	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
CMHMHKIO_00245	6.73e-211	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_00246	6.41e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMHMHKIO_00247	3.43e-162	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
CMHMHKIO_00248	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
CMHMHKIO_00249	1.35e-208	-	-	-	C	-	-	-	nadph quinone reductase
CMHMHKIO_00250	3.8e-316	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
CMHMHKIO_00251	2.05e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
CMHMHKIO_00252	2.22e-154	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
CMHMHKIO_00253	4.52e-160	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
CMHMHKIO_00254	0.000673	-	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Psort location CytoplasmicMembrane, score
CMHMHKIO_00255	1.62e-159	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	proteolysis
CMHMHKIO_00256	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
CMHMHKIO_00257	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
CMHMHKIO_00258	3.79e-147	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
CMHMHKIO_00259	1.9e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMHMHKIO_00260	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
CMHMHKIO_00261	3.83e-86	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
CMHMHKIO_00262	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CMHMHKIO_00263	1.72e-140	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
CMHMHKIO_00264	7.74e-163	kdgR	-	-	K	-	-	-	FCD domain
CMHMHKIO_00265	3.45e-74	ps105	-	-	-	-	-	-	-
CMHMHKIO_00266	3.38e-210	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
CMHMHKIO_00267	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
CMHMHKIO_00268	6.85e-310	-	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_00270	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
CMHMHKIO_00271	2.34e-140	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
CMHMHKIO_00273	3.93e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_00274	3.55e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CMHMHKIO_00275	2.28e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_00276	8.51e-286	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_00277	0.000666	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMHMHKIO_00279	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
CMHMHKIO_00280	3.61e-46	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
CMHMHKIO_00281	3.09e-133	dpsB	-	-	P	-	-	-	Belongs to the Dps family
CMHMHKIO_00282	2.13e-150	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
CMHMHKIO_00283	2.39e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CMHMHKIO_00284	1.74e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CMHMHKIO_00285	6.7e-135	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
CMHMHKIO_00286	7.66e-178	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
CMHMHKIO_00287	1.84e-237	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CMHMHKIO_00288	1.02e-298	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CMHMHKIO_00289	1.47e-60	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_00290	8.8e-103	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_00291	6.16e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
CMHMHKIO_00292	3.34e-268	-	-	-	-	-	-	-	-
CMHMHKIO_00293	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_00294	1.04e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_00296	1.28e-166	-	-	-	-	-	-	-	-
CMHMHKIO_00297	2.19e-289	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
CMHMHKIO_00298	9.92e-212	-	-	-	-	-	-	-	-
CMHMHKIO_00299	1.38e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMHMHKIO_00300	7.63e-85	-	-	-	S	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
CMHMHKIO_00302	7.65e-61	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
CMHMHKIO_00303	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
CMHMHKIO_00305	5.43e-180	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CMHMHKIO_00306	4.95e-215	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMHMHKIO_00307	6.4e-282	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CMHMHKIO_00308	4.4e-116	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CMHMHKIO_00309	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CMHMHKIO_00310	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CMHMHKIO_00311	4.38e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CMHMHKIO_00312	1.74e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMHMHKIO_00313	8.46e-84	-	-	-	-	-	-	-	-
CMHMHKIO_00314	1.35e-97	-	-	-	L	-	-	-	NUDIX domain
CMHMHKIO_00315	4.62e-193	-	-	-	EG	-	-	-	EamA-like transporter family
CMHMHKIO_00316	3.35e-125	-	-	-	S	-	-	-	Phospholipase A2
CMHMHKIO_00318	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
CMHMHKIO_00319	1.35e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CMHMHKIO_00320	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
CMHMHKIO_00321	2.31e-277	-	-	-	-	-	-	-	-
CMHMHKIO_00323	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMHMHKIO_00324	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
CMHMHKIO_00325	4.34e-75	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
CMHMHKIO_00326	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
CMHMHKIO_00327	1.78e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
CMHMHKIO_00328	3.32e-263	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMHMHKIO_00329	1.91e-46	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
CMHMHKIO_00330	2.26e-215	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_00331	3.78e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CMHMHKIO_00332	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
CMHMHKIO_00333	1.45e-172	-	-	-	-	-	-	-	-
CMHMHKIO_00334	4e-133	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
CMHMHKIO_00335	0.0	-	-	-	-	-	-	-	-
CMHMHKIO_00336	4.68e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
CMHMHKIO_00337	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
CMHMHKIO_00338	4.19e-65	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
CMHMHKIO_00339	1.35e-88	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
CMHMHKIO_00340	1.24e-14	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
CMHMHKIO_00341	3.72e-218	-	-	-	S	-	-	-	Putative esterase
CMHMHKIO_00342	1.83e-256	-	-	-	-	-	-	-	-
CMHMHKIO_00343	1.47e-136	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
CMHMHKIO_00344	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
CMHMHKIO_00345	4.68e-109	-	-	-	F	-	-	-	NUDIX domain
CMHMHKIO_00346	4.68e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMHMHKIO_00347	9.57e-30	-	-	-	-	-	-	-	-
CMHMHKIO_00348	1.09e-209	-	-	-	S	-	-	-	zinc-ribbon domain
CMHMHKIO_00349	5.93e-262	pbpX	-	-	V	-	-	-	Beta-lactamase
CMHMHKIO_00350	4.01e-240	ydbI	-	-	K	-	-	-	AI-2E family transporter
CMHMHKIO_00351	4.31e-166	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CMHMHKIO_00352	1.41e-85	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
CMHMHKIO_00353	2.58e-226	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CMHMHKIO_00354	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CMHMHKIO_00355	3.51e-216	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
CMHMHKIO_00356	2.03e-189	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
CMHMHKIO_00357	9.19e-285	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
CMHMHKIO_00358	1.39e-176	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
CMHMHKIO_00359	2.6e-96	usp1	-	-	T	-	-	-	Universal stress protein family
CMHMHKIO_00360	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
CMHMHKIO_00361	7.73e-196	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CMHMHKIO_00362	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
CMHMHKIO_00363	7.09e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
CMHMHKIO_00364	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CMHMHKIO_00365	2.16e-275	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
CMHMHKIO_00366	7.64e-51	-	-	-	-	-	-	-	-
CMHMHKIO_00367	2.23e-224	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
CMHMHKIO_00368	3.03e-227	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMHMHKIO_00369	3.99e-278	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CMHMHKIO_00370	3.74e-69	-	-	-	-	-	-	-	-
CMHMHKIO_00371	9.39e-166	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
CMHMHKIO_00372	2.8e-94	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
CMHMHKIO_00373	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
CMHMHKIO_00375	8.65e-182	mprF	2.3.2.3	-	M	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	lysyltransferase activity
CMHMHKIO_00377	6.9e-262	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CMHMHKIO_00378	6.42e-208	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
CMHMHKIO_00379	3.26e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CMHMHKIO_00380	1.92e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMHMHKIO_00381	9.96e-212	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
CMHMHKIO_00382	2.61e-280	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMHMHKIO_00383	6.81e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
CMHMHKIO_00384	9.19e-209	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_00385	1.28e-144	-	-	-	I	-	-	-	ABC-2 family transporter protein
CMHMHKIO_00386	2.06e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
CMHMHKIO_00387	1.84e-260	ald1	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
CMHMHKIO_00388	3.18e-240	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CMHMHKIO_00389	2.56e-162	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
CMHMHKIO_00390	1.06e-262	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
CMHMHKIO_00391	8.34e-83	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
CMHMHKIO_00392	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CMHMHKIO_00393	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
CMHMHKIO_00394	0.0	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
CMHMHKIO_00395	4.96e-127	-	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Bacterial regulatory proteins, tetR family
CMHMHKIO_00396	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMHMHKIO_00397	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMHMHKIO_00398	2.51e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
CMHMHKIO_00399	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
CMHMHKIO_00400	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
CMHMHKIO_00401	3.15e-98	-	-	-	S	-	-	-	NusG domain II
CMHMHKIO_00402	4.1e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMHMHKIO_00403	1.98e-172	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
CMHMHKIO_00404	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
CMHMHKIO_00405	1.7e-190	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
CMHMHKIO_00406	2.39e-109	-	-	-	-	-	-	-	-
CMHMHKIO_00407	1.09e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
CMHMHKIO_00408	3.77e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
CMHMHKIO_00409	1.62e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
CMHMHKIO_00410	7.79e-11	-	-	-	-	-	-	-	-
CMHMHKIO_00411	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHMHKIO_00412	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
CMHMHKIO_00413	1.34e-176	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
CMHMHKIO_00414	3.16e-180	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
CMHMHKIO_00415	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
CMHMHKIO_00416	5.16e-17	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
CMHMHKIO_00417	1.25e-102	-	-	-	-	-	-	-	-
CMHMHKIO_00418	5.33e-76	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMHMHKIO_00419	4.13e-187	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
CMHMHKIO_00420	0.0	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
CMHMHKIO_00421	9.15e-264	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
CMHMHKIO_00422	8.79e-283	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
CMHMHKIO_00423	1.44e-186	-	-	-	-	-	-	-	-
CMHMHKIO_00424	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
CMHMHKIO_00425	1.17e-261	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
CMHMHKIO_00426	1.23e-223	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMHMHKIO_00427	7.59e-122	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
CMHMHKIO_00428	4.23e-219	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
CMHMHKIO_00429	1.01e-165	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
CMHMHKIO_00430	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
CMHMHKIO_00431	2.47e-136	-	-	-	-	-	-	-	-
CMHMHKIO_00432	0.0	-	-	-	-	-	-	-	-
CMHMHKIO_00433	3.5e-271	-	-	-	-	-	-	-	-
CMHMHKIO_00434	6.8e-95	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMHMHKIO_00435	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMHMHKIO_00436	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CMHMHKIO_00437	3.69e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
CMHMHKIO_00438	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
CMHMHKIO_00439	5.14e-212	-	-	-	GM	-	-	-	NmrA-like family
CMHMHKIO_00440	4.81e-298	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
CMHMHKIO_00441	1.19e-184	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
CMHMHKIO_00442	3.05e-194	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CMHMHKIO_00443	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
CMHMHKIO_00444	2.76e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CMHMHKIO_00445	8.8e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CMHMHKIO_00446	6.98e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CMHMHKIO_00447	2.03e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
CMHMHKIO_00448	1.52e-212	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
CMHMHKIO_00449	5.55e-221	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
CMHMHKIO_00450	1.38e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMHMHKIO_00451	1.96e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMHMHKIO_00452	2.44e-99	-	-	-	K	-	-	-	Winged helix DNA-binding domain
CMHMHKIO_00453	6.79e-95	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
CMHMHKIO_00454	7.3e-246	-	-	-	E	-	-	-	Alpha/beta hydrolase family
CMHMHKIO_00455	5.57e-290	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
CMHMHKIO_00456	6.58e-227	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
CMHMHKIO_00457	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
CMHMHKIO_00458	1.2e-302	-	-	-	I	-	-	-	Acyltransferase family
CMHMHKIO_00459	1.17e-154	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMHMHKIO_00460	1.02e-192	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_00461	7.94e-175	XK27_06950	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMHMHKIO_00462	2.2e-175	XK27_06945	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMHMHKIO_00463	2.04e-175	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_00464	1.17e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
CMHMHKIO_00465	1.28e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
CMHMHKIO_00466	9.26e-146	-	-	-	-	-	-	-	-
CMHMHKIO_00467	1.29e-74	-	-	-	-	-	-	-	-
CMHMHKIO_00468	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
CMHMHKIO_00469	2.98e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMHMHKIO_00470	1.46e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_00471	2.61e-238	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CMHMHKIO_00472	3.14e-165	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMHMHKIO_00473	1.5e-44	-	-	-	-	-	-	-	-
CMHMHKIO_00474	3.24e-171	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
CMHMHKIO_00475	1.39e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMHMHKIO_00476	1.13e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMHMHKIO_00477	4.71e-203	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMHMHKIO_00478	1.15e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMHMHKIO_00479	9.02e-154	-	-	-	-	-	-	-	-
CMHMHKIO_00480	5.46e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
CMHMHKIO_00481	1.26e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMHMHKIO_00482	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMHMHKIO_00483	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMHMHKIO_00484	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
CMHMHKIO_00485	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMHMHKIO_00486	1.11e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CMHMHKIO_00487	4.24e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CMHMHKIO_00488	4.07e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CMHMHKIO_00489	2.6e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
CMHMHKIO_00490	5.74e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMHMHKIO_00491	1.62e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMHMHKIO_00492	2.61e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMHMHKIO_00493	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMHMHKIO_00494	8.67e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMHMHKIO_00495	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMHMHKIO_00496	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMHMHKIO_00497	5.93e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMHMHKIO_00498	3.55e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
CMHMHKIO_00499	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMHMHKIO_00500	2.8e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMHMHKIO_00501	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMHMHKIO_00502	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMHMHKIO_00503	7.23e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMHMHKIO_00504	1.02e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CMHMHKIO_00505	1.98e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
CMHMHKIO_00506	4.01e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMHMHKIO_00507	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
CMHMHKIO_00508	3.63e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
CMHMHKIO_00509	2.38e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
CMHMHKIO_00510	3.54e-257	-	-	-	K	-	-	-	WYL domain
CMHMHKIO_00511	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMHMHKIO_00512	2.4e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CMHMHKIO_00513	1.11e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMHMHKIO_00514	0.0	-	-	-	M	-	-	-	domain protein
CMHMHKIO_00515	1.47e-46	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
CMHMHKIO_00516	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMHMHKIO_00517	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMHMHKIO_00518	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMHMHKIO_00519	4.32e-105	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
CMHMHKIO_00528	1.33e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMHMHKIO_00529	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
CMHMHKIO_00530	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
CMHMHKIO_00531	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
CMHMHKIO_00533	4.15e-170	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
CMHMHKIO_00534	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
CMHMHKIO_00535	8.32e-128	-	-	-	-	-	-	-	-
CMHMHKIO_00536	2.94e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CMHMHKIO_00537	3e-249	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
CMHMHKIO_00538	8.02e-114	-	-	-	-	-	-	-	-
CMHMHKIO_00539	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CMHMHKIO_00540	3.08e-152	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CMHMHKIO_00541	2.44e-208	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CMHMHKIO_00542	1.25e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CMHMHKIO_00543	1.61e-41	-	-	-	-	-	-	-	-
CMHMHKIO_00544	7.43e-97	-	-	-	-	-	-	-	-
CMHMHKIO_00545	1.99e-199	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CMHMHKIO_00546	4.14e-163	citR	-	-	K	-	-	-	FCD
CMHMHKIO_00547	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
CMHMHKIO_00548	1.18e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CMHMHKIO_00549	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
CMHMHKIO_00550	7.46e-201	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
CMHMHKIO_00551	3.41e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
CMHMHKIO_00552	4.66e-232	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CMHMHKIO_00553	3.26e-07	-	-	-	-	-	-	-	-
CMHMHKIO_00554	5.58e-251	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
CMHMHKIO_00555	1.71e-62	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
CMHMHKIO_00556	3.17e-71	-	-	-	-	-	-	-	-
CMHMHKIO_00557	1.43e-307	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
CMHMHKIO_00558	1.72e-53	-	-	-	-	-	-	-	-
CMHMHKIO_00559	2.68e-135	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CMHMHKIO_00560	2.1e-114	-	-	-	K	-	-	-	GNAT family
CMHMHKIO_00561	6.93e-140	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
CMHMHKIO_00562	1.13e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
CMHMHKIO_00563	7.71e-192	ORF00048	-	-	-	-	-	-	-
CMHMHKIO_00564	6.35e-177	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
CMHMHKIO_00565	1.42e-216	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_00566	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
CMHMHKIO_00567	1.7e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
CMHMHKIO_00568	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_00569	2.86e-161	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CMHMHKIO_00570	6.95e-239	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMHMHKIO_00571	4.73e-209	-	-	-	S	-	-	-	Alpha beta hydrolase
CMHMHKIO_00572	8.13e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
CMHMHKIO_00573	1.23e-163	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMHMHKIO_00574	4.41e-20	-	-	-	-	-	-	-	-
CMHMHKIO_00575	6.6e-134	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CMHMHKIO_00576	1.71e-206	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
CMHMHKIO_00577	3.16e-262	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
CMHMHKIO_00579	7.11e-228	-	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMHMHKIO_00580	2.54e-216	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_00581	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CMHMHKIO_00582	1.19e-164	-	-	-	S	-	-	-	DJ-1/PfpI family
CMHMHKIO_00583	2.12e-70	-	-	-	K	-	-	-	Transcriptional
CMHMHKIO_00584	6.68e-52	-	-	-	-	-	-	-	-
CMHMHKIO_00585	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
CMHMHKIO_00586	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
CMHMHKIO_00588	3.24e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
CMHMHKIO_00589	7.96e-20	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
CMHMHKIO_00590	0.0	-	-	-	M	-	-	-	LysM domain
CMHMHKIO_00591	3.38e-173	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
CMHMHKIO_00592	2.49e-167	mga	-	-	K	ko:K02538	-	ko00000,ko03000	transcriptional antiterminator
CMHMHKIO_00593	3.39e-156	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CMHMHKIO_00594	2.57e-109	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CMHMHKIO_00595	3.33e-265	-	-	-	S	-	-	-	DUF218 domain
CMHMHKIO_00596	5.63e-177	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
CMHMHKIO_00597	2.62e-261	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
CMHMHKIO_00598	3.82e-278	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
CMHMHKIO_00599	3.79e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
CMHMHKIO_00600	4.1e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
CMHMHKIO_00601	1.1e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
CMHMHKIO_00602	2.66e-53	-	-	-	S	-	-	-	Glycine-rich SFCGS
CMHMHKIO_00603	1.82e-74	-	-	-	S	-	-	-	PRD domain
CMHMHKIO_00604	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
CMHMHKIO_00605	8.74e-161	-	-	-	H	-	-	-	Pfam:Transaldolase
CMHMHKIO_00606	2.24e-84	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
CMHMHKIO_00607	3.58e-262	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
CMHMHKIO_00608	5.81e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
CMHMHKIO_00609	2.63e-115	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
CMHMHKIO_00610	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
CMHMHKIO_00611	4.13e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
CMHMHKIO_00612	1.57e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
CMHMHKIO_00613	2.51e-194	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMHMHKIO_00614	1.53e-212	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
CMHMHKIO_00615	8.64e-178	-	-	-	K	-	-	-	DeoR C terminal sensor domain
CMHMHKIO_00616	3.17e-149	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
CMHMHKIO_00617	3.36e-61	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_00618	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CMHMHKIO_00619	4.89e-105	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_00620	4.59e-275	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
CMHMHKIO_00621	2.92e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CMHMHKIO_00622	1.1e-254	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
CMHMHKIO_00623	4.26e-91	-	-	-	G	-	-	-	DeoC/LacD family aldolase
CMHMHKIO_00624	3.93e-58	-	4.1.2.13	-	G	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	lyase activity
CMHMHKIO_00625	1.15e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
CMHMHKIO_00626	1.29e-201	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_00627	1.95e-172	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_00628	2.79e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_00629	1.23e-95	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_00630	3.07e-263	-	1.1.1.405	-	E	ko:K05352	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
CMHMHKIO_00631	1.67e-173	-	-	-	K	-	-	-	DeoR C terminal sensor domain
CMHMHKIO_00632	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
CMHMHKIO_00633	5.08e-207	-	-	-	GK	-	-	-	ROK family
CMHMHKIO_00634	6.65e-234	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
CMHMHKIO_00635	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
CMHMHKIO_00636	2.59e-170	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
CMHMHKIO_00637	0.0	-	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase
CMHMHKIO_00638	1.67e-272	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
CMHMHKIO_00639	2.07e-265	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
CMHMHKIO_00640	1.07e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF4428)
CMHMHKIO_00641	0.0	-	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
CMHMHKIO_00642	6.91e-261	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
CMHMHKIO_00643	1.34e-199	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_00644	3.52e-176	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_00645	5.64e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_00646	1.03e-92	ahaA	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_00647	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_00648	9.31e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
CMHMHKIO_00649	1.2e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
CMHMHKIO_00650	3.71e-146	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMHMHKIO_00651	8.68e-74	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
CMHMHKIO_00652	1.93e-80	-	-	-	-	-	-	-	-
CMHMHKIO_00653	2.2e-178	-	-	-	-	-	-	-	-
CMHMHKIO_00654	6.69e-61	-	-	-	S	-	-	-	Enterocin A Immunity
CMHMHKIO_00655	2.22e-60	-	-	-	S	-	-	-	Enterocin A Immunity
CMHMHKIO_00656	3.61e-61	spiA	-	-	K	-	-	-	TRANSCRIPTIONal
CMHMHKIO_00657	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
CMHMHKIO_00659	5.75e-72	-	-	-	-	-	-	-	-
CMHMHKIO_00660	5.05e-313	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
CMHMHKIO_00661	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMHMHKIO_00662	2.95e-50	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
CMHMHKIO_00665	1.35e-174	-	2.7.13.3	-	T	ko:K02476,ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
CMHMHKIO_00666	7.99e-184	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
CMHMHKIO_00668	1.27e-15	-	-	-	-	-	-	-	-
CMHMHKIO_00671	1.66e-188	-	-	-	S	-	-	-	CAAX protease self-immunity
CMHMHKIO_00673	5.62e-75	-	-	-	-	-	-	-	-
CMHMHKIO_00674	1.66e-05	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
CMHMHKIO_00675	1.18e-72	-	-	-	S	-	-	-	Enterocin A Immunity
CMHMHKIO_00676	7.86e-138	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CMHMHKIO_00680	8.37e-231	ydhF	-	-	S	-	-	-	Aldo keto reductase
CMHMHKIO_00681	3.51e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMHMHKIO_00682	1.98e-278	yqiG	-	-	C	-	-	-	Oxidoreductase
CMHMHKIO_00683	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CMHMHKIO_00684	1.88e-174	-	-	-	-	-	-	-	-
CMHMHKIO_00685	6.42e-28	-	-	-	-	-	-	-	-
CMHMHKIO_00686	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CMHMHKIO_00687	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CMHMHKIO_00688	1.14e-72	-	-	-	-	-	-	-	-
CMHMHKIO_00689	4.42e-306	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMHMHKIO_00690	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
CMHMHKIO_00691	1.53e-35	-	-	-	-	-	-	-	-
CMHMHKIO_00692	2.22e-144	-	-	-	P	-	-	-	Cation efflux family
CMHMHKIO_00693	1.23e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
CMHMHKIO_00694	6.58e-226	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CMHMHKIO_00695	1.07e-187	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
CMHMHKIO_00696	3.38e-170	-	3.6.3.35	-	P	ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CMHMHKIO_00697	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
CMHMHKIO_00698	2.9e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMHMHKIO_00700	3.6e-42	-	-	-	L	ko:K07481	-	ko00000	Transposase
CMHMHKIO_00701	1.29e-151	-	-	-	L	-	-	-	Transposase
CMHMHKIO_00702	2.47e-125	-	-	-	L	-	-	-	Transposase
CMHMHKIO_00703	4.95e-134	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
CMHMHKIO_00704	2.47e-251	-	-	-	S	ko:K06915	-	ko00000	helicase activity
CMHMHKIO_00705	1.1e-227	-	-	-	S	-	-	-	SIR2-like domain
CMHMHKIO_00707	0.0	-	-	-	-	-	-	-	-
CMHMHKIO_00708	7.29e-06	-	-	-	-	-	-	-	-
CMHMHKIO_00709	1.55e-10	-	-	-	L	-	-	-	Transposase IS66 family
CMHMHKIO_00710	1.6e-10	-	-	-	L	ko:K07484	-	ko00000	PFAM transposase IS66
CMHMHKIO_00711	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMHMHKIO_00712	1.23e-111	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
CMHMHKIO_00713	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CMHMHKIO_00714	6.1e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CMHMHKIO_00715	6.03e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CMHMHKIO_00716	1.24e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CMHMHKIO_00717	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CMHMHKIO_00718	3.79e-309	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CMHMHKIO_00719	1.98e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
CMHMHKIO_00720	1.97e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
CMHMHKIO_00721	4.82e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
CMHMHKIO_00722	3.25e-192	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
CMHMHKIO_00723	1.23e-112	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
CMHMHKIO_00724	2.31e-149	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CMHMHKIO_00725	8.63e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
CMHMHKIO_00726	4.79e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CMHMHKIO_00727	3.29e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
CMHMHKIO_00728	2.32e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
CMHMHKIO_00729	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMHMHKIO_00730	7.11e-60	-	-	-	-	-	-	-	-
CMHMHKIO_00731	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
CMHMHKIO_00732	1.66e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CMHMHKIO_00733	1.6e-68	ftsL	-	-	D	-	-	-	cell division protein FtsL
CMHMHKIO_00734	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CMHMHKIO_00735	1.33e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMHMHKIO_00736	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMHMHKIO_00737	4e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMHMHKIO_00738	3.57e-201	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CMHMHKIO_00739	1.44e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CMHMHKIO_00740	3.25e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMHMHKIO_00741	7.24e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CMHMHKIO_00742	5.58e-60	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	integral membrane protein
CMHMHKIO_00743	2.14e-188	ylmH	-	-	S	-	-	-	S4 domain protein
CMHMHKIO_00744	2.12e-122	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
CMHMHKIO_00745	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMHMHKIO_00746	4.62e-48	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CMHMHKIO_00747	5.93e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CMHMHKIO_00748	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_00749	7.29e-270	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
CMHMHKIO_00750	2.8e-151	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CMHMHKIO_00751	1.83e-124	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
CMHMHKIO_00752	1.42e-39	-	-	-	-	-	-	-	-
CMHMHKIO_00753	1.95e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMHMHKIO_00754	1.39e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CMHMHKIO_00755	1.21e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
CMHMHKIO_00756	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
CMHMHKIO_00757	0.0	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CMHMHKIO_00759	8.1e-160	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
CMHMHKIO_00760	1.62e-151	-	-	-	S	-	-	-	repeat protein
CMHMHKIO_00761	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CMHMHKIO_00762	2.86e-312	-	-	-	S	-	-	-	Sterol carrier protein domain
CMHMHKIO_00763	2.55e-46	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CMHMHKIO_00764	3.58e-145	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CMHMHKIO_00765	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMHMHKIO_00766	2.02e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
CMHMHKIO_00767	1.11e-95	-	-	-	-	-	-	-	-
CMHMHKIO_00768	4.23e-64	-	-	-	-	-	-	-	-
CMHMHKIO_00769	4.82e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMHMHKIO_00770	5.13e-112	-	-	-	S	-	-	-	E1-E2 ATPase
CMHMHKIO_00771	1.42e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
CMHMHKIO_00772	1.15e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
CMHMHKIO_00773	0.0	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CMHMHKIO_00774	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
CMHMHKIO_00775	4.32e-202	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
CMHMHKIO_00776	6.15e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
CMHMHKIO_00777	3.56e-189	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
CMHMHKIO_00778	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
CMHMHKIO_00779	1.66e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CMHMHKIO_00780	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CMHMHKIO_00781	8.46e-84	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
CMHMHKIO_00782	9.93e-130	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
CMHMHKIO_00783	1.08e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMHMHKIO_00784	9.02e-234	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
CMHMHKIO_00785	1.09e-151	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
CMHMHKIO_00786	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
CMHMHKIO_00787	5.08e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CMHMHKIO_00788	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
CMHMHKIO_00790	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMHMHKIO_00791	3.82e-62	-	-	-	-	-	-	-	-
CMHMHKIO_00792	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMHMHKIO_00793	1.93e-213	-	-	-	S	-	-	-	Tetratricopeptide repeat
CMHMHKIO_00794	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMHMHKIO_00795	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
CMHMHKIO_00796	9.55e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CMHMHKIO_00797	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMHMHKIO_00798	2.74e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
CMHMHKIO_00799	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
CMHMHKIO_00800	3.33e-28	-	-	-	-	-	-	-	-
CMHMHKIO_00801	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CMHMHKIO_00802	6.58e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_00803	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CMHMHKIO_00804	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
CMHMHKIO_00805	2.76e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CMHMHKIO_00806	1.61e-169	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
CMHMHKIO_00807	5.83e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMHMHKIO_00808	0.0	oatA	-	-	I	-	-	-	Acyltransferase
CMHMHKIO_00809	2.71e-233	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CMHMHKIO_00810	1.83e-183	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
CMHMHKIO_00811	2.47e-65	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
CMHMHKIO_00812	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMHMHKIO_00813	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
CMHMHKIO_00814	6.3e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
CMHMHKIO_00815	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
CMHMHKIO_00816	1.49e-185	-	-	-	-	-	-	-	-
CMHMHKIO_00817	3.31e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
CMHMHKIO_00818	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
CMHMHKIO_00819	2.21e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CMHMHKIO_00820	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
CMHMHKIO_00821	2.6e-96	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
CMHMHKIO_00822	1.03e-207	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
CMHMHKIO_00823	9.95e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
CMHMHKIO_00824	1.59e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMHMHKIO_00825	5.33e-160	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CMHMHKIO_00826	8.74e-139	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CMHMHKIO_00827	1.1e-175	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CMHMHKIO_00828	1.52e-123	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CMHMHKIO_00829	1.16e-60	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
CMHMHKIO_00830	2.72e-236	-	-	-	S	-	-	-	Helix-turn-helix domain
CMHMHKIO_00831	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CMHMHKIO_00832	6.76e-111	-	-	-	M	-	-	-	Lysin motif
CMHMHKIO_00833	2.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
CMHMHKIO_00834	1.72e-303	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
CMHMHKIO_00835	7.41e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
CMHMHKIO_00836	1.2e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMHMHKIO_00837	1.52e-302	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
CMHMHKIO_00838	8.71e-200	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMHMHKIO_00839	5.31e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CMHMHKIO_00840	2.95e-110	-	-	-	-	-	-	-	-
CMHMHKIO_00841	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_00842	2.96e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMHMHKIO_00843	3.64e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMHMHKIO_00844	1.83e-148	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
CMHMHKIO_00845	4.9e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
CMHMHKIO_00846	2.93e-197	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CMHMHKIO_00847	3.18e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
CMHMHKIO_00848	4.47e-113	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMHMHKIO_00849	1.03e-54	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
CMHMHKIO_00850	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
CMHMHKIO_00851	1.3e-52	XK27_02555	-	-	-	-	-	-	-
CMHMHKIO_00853	7.6e-246	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
CMHMHKIO_00854	2.52e-195	-	-	-	K	-	-	-	Helix-turn-helix domain
CMHMHKIO_00856	2.53e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CMHMHKIO_00857	2.49e-179	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMHMHKIO_00858	3.27e-189	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
CMHMHKIO_00859	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMHMHKIO_00860	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CMHMHKIO_00861	1.66e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
CMHMHKIO_00862	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CMHMHKIO_00863	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CMHMHKIO_00864	1.32e-219	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CMHMHKIO_00865	2.14e-140	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMHMHKIO_00866	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMHMHKIO_00867	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMHMHKIO_00868	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
CMHMHKIO_00869	1.27e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMHMHKIO_00870	2.6e-232	-	-	-	K	-	-	-	LysR substrate binding domain
CMHMHKIO_00871	5.59e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
CMHMHKIO_00872	3.63e-270	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
CMHMHKIO_00873	7.18e-79	-	-	-	-	-	-	-	-
CMHMHKIO_00874	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
CMHMHKIO_00875	2.68e-176	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_00876	1.09e-222	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
CMHMHKIO_00877	1.75e-159	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
CMHMHKIO_00878	5.52e-243	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
CMHMHKIO_00879	1.07e-43	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_00880	6.04e-94	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_00881	2.92e-144	-	-	-	C	-	-	-	Nitroreductase family
CMHMHKIO_00882	2.07e-261	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CMHMHKIO_00883	8.66e-70	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
CMHMHKIO_00884	1.01e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CMHMHKIO_00885	7.36e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CMHMHKIO_00886	1.37e-160	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CMHMHKIO_00887	4.89e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CMHMHKIO_00888	3.22e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
CMHMHKIO_00889	4.33e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CMHMHKIO_00890	2.06e-144	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CMHMHKIO_00891	3.83e-278	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CMHMHKIO_00892	6.2e-264	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CMHMHKIO_00893	9.68e-134	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
CMHMHKIO_00894	6.21e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
CMHMHKIO_00895	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
CMHMHKIO_00896	6.51e-69	-	-	-	S	-	-	-	MazG-like family
CMHMHKIO_00897	1.42e-250	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
CMHMHKIO_00898	2.13e-227	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CMHMHKIO_00899	9.61e-289	bfmBB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
CMHMHKIO_00900	2.14e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
CMHMHKIO_00901	9.14e-239	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
CMHMHKIO_00902	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
CMHMHKIO_00903	6.69e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Acetokinase family
CMHMHKIO_00904	1.74e-190	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Phosphate acetyl/butaryl transferase
CMHMHKIO_00905	1.02e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMHMHKIO_00906	4.62e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CMHMHKIO_00907	5.67e-200	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMHMHKIO_00908	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CMHMHKIO_00909	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CMHMHKIO_00910	5.35e-307	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CMHMHKIO_00911	9.29e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CMHMHKIO_00912	1.64e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
CMHMHKIO_00913	1.05e-125	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMHMHKIO_00914	6.3e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CMHMHKIO_00915	2.41e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMHMHKIO_00916	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
CMHMHKIO_00917	8.5e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
CMHMHKIO_00918	2.37e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
CMHMHKIO_00919	5.13e-144	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
CMHMHKIO_00920	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMHMHKIO_00921	3.85e-63	-	-	-	-	-	-	-	-
CMHMHKIO_00922	0.0	-	-	-	S	-	-	-	Mga helix-turn-helix domain
CMHMHKIO_00923	8.72e-52	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
CMHMHKIO_00924	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMHMHKIO_00925	8.83e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMHMHKIO_00926	2.26e-212	lysR	-	-	K	-	-	-	Transcriptional regulator
CMHMHKIO_00927	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
CMHMHKIO_00928	3.5e-249	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
CMHMHKIO_00929	8.85e-47	-	-	-	-	-	-	-	-
CMHMHKIO_00930	2.2e-223	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
CMHMHKIO_00931	2.31e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
CMHMHKIO_00932	7.09e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CMHMHKIO_00933	6.54e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
CMHMHKIO_00934	5.12e-157	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CMHMHKIO_00935	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
CMHMHKIO_00936	5.94e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
CMHMHKIO_00937	7.61e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMHMHKIO_00938	3.19e-146	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
CMHMHKIO_00939	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
CMHMHKIO_00940	9.84e-281	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
CMHMHKIO_00941	3.5e-112	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
CMHMHKIO_00943	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
CMHMHKIO_00944	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
CMHMHKIO_00945	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CMHMHKIO_00946	7.89e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
CMHMHKIO_00947	1.62e-232	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
CMHMHKIO_00948	5.56e-245	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CMHMHKIO_00949	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
CMHMHKIO_00950	4.61e-224	-	-	-	-	-	-	-	-
CMHMHKIO_00951	5.49e-185	-	-	-	-	-	-	-	-
CMHMHKIO_00952	2.32e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CMHMHKIO_00953	1.48e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
CMHMHKIO_00954	1.4e-191	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CMHMHKIO_00955	1.61e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
CMHMHKIO_00956	9.19e-249	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CMHMHKIO_00957	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMHMHKIO_00958	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
CMHMHKIO_00959	1.48e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
CMHMHKIO_00960	4.99e-72	-	-	-	-	-	-	-	-
CMHMHKIO_00961	7.92e-74	-	-	-	-	-	-	-	-
CMHMHKIO_00962	2.11e-183	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
CMHMHKIO_00963	1.17e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMHMHKIO_00964	1.38e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CMHMHKIO_00965	6.78e-82	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
CMHMHKIO_00966	5.09e-107	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMHMHKIO_00967	8.02e-230	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
CMHMHKIO_00969	1.81e-88	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
CMHMHKIO_00970	3.98e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
CMHMHKIO_00971	8.44e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CMHMHKIO_00972	1.05e-211	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CMHMHKIO_00973	3.1e-216	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMHMHKIO_00974	7.56e-108	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
CMHMHKIO_00975	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CMHMHKIO_00976	3.25e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
CMHMHKIO_00978	7.04e-217	-	-	-	C	-	-	-	nadph quinone reductase
CMHMHKIO_00979	2.55e-100	-	-	-	-	-	-	-	-
CMHMHKIO_00980	5.67e-191	-	-	-	K	-	-	-	Helix-turn-helix
CMHMHKIO_00981	0.0	-	-	-	-	-	-	-	-
CMHMHKIO_00982	2.41e-201	-	-	-	V	-	-	-	ABC transporter
CMHMHKIO_00983	2.36e-109	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
CMHMHKIO_00984	1.98e-314	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
CMHMHKIO_00985	1.35e-150	-	-	-	J	-	-	-	HAD-hyrolase-like
CMHMHKIO_00986	5.55e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMHMHKIO_00987	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMHMHKIO_00988	5.49e-58	-	-	-	-	-	-	-	-
CMHMHKIO_00989	3.13e-170	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CMHMHKIO_00990	1.74e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
CMHMHKIO_00991	3.49e-113	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
CMHMHKIO_00992	1.54e-144	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
CMHMHKIO_00993	2.23e-50	-	-	-	-	-	-	-	-
CMHMHKIO_00994	8.05e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
CMHMHKIO_00995	6.1e-27	-	-	-	-	-	-	-	-
CMHMHKIO_00996	1.72e-64	-	-	-	-	-	-	-	-
CMHMHKIO_00997	9.31e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_00999	3.1e-143	-	-	-	S	-	-	-	Flavodoxin-like fold
CMHMHKIO_01000	1.54e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_01001	7.25e-200	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
CMHMHKIO_01002	1.66e-71	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
CMHMHKIO_01003	2.01e-118	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMHMHKIO_01004	1.7e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMHMHKIO_01005	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
CMHMHKIO_01006	8.85e-76	-	-	-	-	-	-	-	-
CMHMHKIO_01007	2.05e-109	-	-	-	S	-	-	-	ASCH
CMHMHKIO_01008	1.32e-33	-	-	-	-	-	-	-	-
CMHMHKIO_01009	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CMHMHKIO_01010	9.45e-261	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CMHMHKIO_01011	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
CMHMHKIO_01012	3.18e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMHMHKIO_01013	5.57e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CMHMHKIO_01014	1.01e-229	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
CMHMHKIO_01015	1.22e-39	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
CMHMHKIO_01016	2.3e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
CMHMHKIO_01017	2.83e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMHMHKIO_01018	4.46e-183	terC	-	-	P	-	-	-	Integral membrane protein TerC family
CMHMHKIO_01019	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMHMHKIO_01020	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMHMHKIO_01021	1.29e-60	ylxQ	-	-	J	-	-	-	ribosomal protein
CMHMHKIO_01022	9.63e-61	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
CMHMHKIO_01023	4.13e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
CMHMHKIO_01024	1.33e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
CMHMHKIO_01025	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMHMHKIO_01026	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CMHMHKIO_01027	3.52e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
CMHMHKIO_01028	7.66e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
CMHMHKIO_01029	6.38e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMHMHKIO_01030	1.73e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CMHMHKIO_01031	5.86e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
CMHMHKIO_01032	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMHMHKIO_01033	1.18e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
CMHMHKIO_01034	1.88e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
CMHMHKIO_01035	2.05e-168	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
CMHMHKIO_01036	8.45e-160	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
CMHMHKIO_01037	1.17e-293	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
CMHMHKIO_01038	4.28e-181	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
CMHMHKIO_01039	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_01040	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_01041	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
CMHMHKIO_01042	2.84e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
CMHMHKIO_01043	9.42e-28	-	-	-	-	-	-	-	-
CMHMHKIO_01044	2e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CMHMHKIO_01045	6.15e-186	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
CMHMHKIO_01046	2.16e-120	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMHMHKIO_01047	1.55e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
CMHMHKIO_01048	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
CMHMHKIO_01049	2.16e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMHMHKIO_01050	1.26e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CMHMHKIO_01051	7.91e-70	-	-	-	-	-	-	-	-
CMHMHKIO_01052	1.57e-233	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CMHMHKIO_01053	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
CMHMHKIO_01054	6.59e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CMHMHKIO_01055	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CMHMHKIO_01056	1.8e-197	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_01057	3.2e-216	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_01058	5.65e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMHMHKIO_01059	4.24e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMHMHKIO_01060	3.21e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMHMHKIO_01061	1.41e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CMHMHKIO_01062	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMHMHKIO_01063	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
CMHMHKIO_01064	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CMHMHKIO_01065	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
CMHMHKIO_01066	2.62e-166	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
CMHMHKIO_01067	4.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
CMHMHKIO_01068	1.38e-221	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CMHMHKIO_01069	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
CMHMHKIO_01070	7.73e-176	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
CMHMHKIO_01071	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMHMHKIO_01072	9.71e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMHMHKIO_01073	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMHMHKIO_01074	3.4e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMHMHKIO_01075	1.77e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CMHMHKIO_01076	2.52e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CMHMHKIO_01077	6.35e-46	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
CMHMHKIO_01078	3.99e-56	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
CMHMHKIO_01079	2.32e-67	-	-	-	-	-	-	-	-
CMHMHKIO_01081	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
CMHMHKIO_01082	7.24e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CMHMHKIO_01083	8.09e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
CMHMHKIO_01084	1.56e-190	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CMHMHKIO_01085	1.42e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMHMHKIO_01086	1.56e-295	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMHMHKIO_01087	4.46e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMHMHKIO_01088	2.34e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMHMHKIO_01089	9.44e-99	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
CMHMHKIO_01090	6.06e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMHMHKIO_01092	2.14e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CMHMHKIO_01093	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
CMHMHKIO_01094	1.77e-74	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
CMHMHKIO_01095	5.83e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
CMHMHKIO_01096	4.92e-18	-	-	-	-	-	-	-	-
CMHMHKIO_01099	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CMHMHKIO_01100	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CMHMHKIO_01101	1.32e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
CMHMHKIO_01102	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
CMHMHKIO_01103	1.41e-305	ynbB	-	-	P	-	-	-	aluminum resistance
CMHMHKIO_01104	3.25e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMHMHKIO_01105	3.33e-35	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
CMHMHKIO_01106	1.93e-96	yqhL	-	-	P	-	-	-	Rhodanese-like protein
CMHMHKIO_01107	1.13e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
CMHMHKIO_01108	6.79e-55	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
CMHMHKIO_01109	2.3e-158	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
CMHMHKIO_01110	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CMHMHKIO_01111	2.14e-80	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
CMHMHKIO_01113	9.51e-168	-	-	-	-	-	-	-	-
CMHMHKIO_01114	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
CMHMHKIO_01115	8e-226	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
CMHMHKIO_01116	2.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_01117	1.44e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_01118	1.23e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CMHMHKIO_01119	6.35e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_01120	8.02e-230	-	-	-	-	-	-	-	-
CMHMHKIO_01122	3.91e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
CMHMHKIO_01123	9.35e-15	-	-	-	-	-	-	-	-
CMHMHKIO_01124	7.28e-144	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
CMHMHKIO_01125	7.28e-92	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_01126	1.99e-197	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
CMHMHKIO_01127	1.55e-312	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMHMHKIO_01128	1.32e-221	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMHMHKIO_01129	5.83e-73	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMHMHKIO_01130	3.12e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMHMHKIO_01131	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
CMHMHKIO_01132	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CMHMHKIO_01133	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
CMHMHKIO_01134	1.45e-281	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
CMHMHKIO_01135	1.18e-255	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CMHMHKIO_01136	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CMHMHKIO_01137	1.06e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
CMHMHKIO_01138	5.01e-136	-	-	-	M	-	-	-	Sortase family
CMHMHKIO_01139	2.29e-187	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMHMHKIO_01140	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
CMHMHKIO_01141	1.94e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
CMHMHKIO_01142	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
CMHMHKIO_01143	4.87e-187	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
CMHMHKIO_01144	1.11e-205	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CMHMHKIO_01145	3.21e-243	-	-	-	-	-	-	-	-
CMHMHKIO_01146	6.93e-169	-	-	-	L	-	-	-	Transposase and inactivated derivatives
CMHMHKIO_01147	3.02e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CMHMHKIO_01148	2.2e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
CMHMHKIO_01149	2.51e-98	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CMHMHKIO_01151	3.96e-274	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
CMHMHKIO_01152	1.04e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
CMHMHKIO_01153	2.87e-11	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
CMHMHKIO_01154	2.9e-153	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
CMHMHKIO_01155	3.01e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
CMHMHKIO_01156	2.35e-159	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_01157	7.59e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMHMHKIO_01158	6.06e-308	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHMHKIO_01159	4.1e-152	-	-	-	G	-	-	-	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CMHMHKIO_01160	1.01e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CMHMHKIO_01161	3.24e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CMHMHKIO_01162	3.82e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
CMHMHKIO_01163	2.38e-212	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CMHMHKIO_01167	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
CMHMHKIO_01168	4.55e-206	-	-	-	-	-	-	-	-
CMHMHKIO_01169	3.03e-158	-	-	-	-	-	-	-	-
CMHMHKIO_01170	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
CMHMHKIO_01171	1.73e-307	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMHMHKIO_01172	1.2e-121	-	-	-	-	-	-	-	-
CMHMHKIO_01173	0.0	strH	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Gram-positive signal peptide protein, YSIRK family
CMHMHKIO_01174	9.12e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CMHMHKIO_01175	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
CMHMHKIO_01176	9.86e-282	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
CMHMHKIO_01177	2.26e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMHMHKIO_01178	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
CMHMHKIO_01179	5.61e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_01180	4.68e-206	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_01181	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_01182	2.72e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_01183	1.23e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
CMHMHKIO_01184	1.01e-55	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CMHMHKIO_01185	9.35e-225	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
CMHMHKIO_01186	1.33e-252	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CMHMHKIO_01187	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHMHKIO_01188	2.96e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_01189	2.04e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
CMHMHKIO_01190	6.02e-242	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
CMHMHKIO_01191	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_01192	4.24e-310	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
CMHMHKIO_01193	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMHMHKIO_01194	2.16e-156	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
CMHMHKIO_01196	4.57e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
CMHMHKIO_01197	6.91e-314	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMHMHKIO_01198	2.8e-144	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
CMHMHKIO_01199	1.76e-168	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CMHMHKIO_01200	1.07e-108	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
CMHMHKIO_01201	6.12e-194	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CMHMHKIO_01202	5.42e-141	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CMHMHKIO_01203	2.31e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CMHMHKIO_01204	0.0	-	-	-	E	-	-	-	Amino acid permease
CMHMHKIO_01205	7e-47	-	-	-	-	-	-	-	-
CMHMHKIO_01206	2.08e-240	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
CMHMHKIO_01207	5.41e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CMHMHKIO_01208	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMHMHKIO_01209	4.84e-198	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CMHMHKIO_01210	1.71e-215	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
CMHMHKIO_01211	3.3e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMHMHKIO_01212	3.09e-56	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
CMHMHKIO_01213	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
CMHMHKIO_01214	7.42e-311	-	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_01215	3.79e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CMHMHKIO_01216	4.65e-134	-	-	-	-	-	-	-	-
CMHMHKIO_01217	4.22e-41	-	-	-	-	-	-	-	-
CMHMHKIO_01218	1.49e-84	-	-	-	-	-	-	-	-
CMHMHKIO_01219	4.54e-91	-	-	-	-	-	-	-	-
CMHMHKIO_01220	1.28e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
CMHMHKIO_01221	1.29e-122	-	-	-	-	-	-	-	-
CMHMHKIO_01222	1.38e-49	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CMHMHKIO_01223	1.4e-09	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
CMHMHKIO_01224	5.78e-32	-	-	-	-	-	-	-	-
CMHMHKIO_01225	2.56e-86	-	-	-	-	-	-	-	-
CMHMHKIO_01227	1.35e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
CMHMHKIO_01228	3e-294	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMHMHKIO_01229	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
CMHMHKIO_01230	8.03e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
CMHMHKIO_01232	3.38e-56	-	-	-	-	-	-	-	-
CMHMHKIO_01233	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CMHMHKIO_01234	1.5e-111	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
CMHMHKIO_01235	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CMHMHKIO_01236	2.51e-28	-	-	-	-	-	-	-	-
CMHMHKIO_01237	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
CMHMHKIO_01238	1.97e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CMHMHKIO_01239	1.11e-106	yjhE	-	-	S	-	-	-	Phage tail protein
CMHMHKIO_01240	1.09e-307	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CMHMHKIO_01241	4.91e-241	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
CMHMHKIO_01242	4.03e-164	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
CMHMHKIO_01243	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CMHMHKIO_01244	2.68e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_01245	0.0	-	-	-	E	-	-	-	Amino Acid
CMHMHKIO_01246	8.52e-212	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CMHMHKIO_01247	4.57e-304	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMHMHKIO_01248	4.67e-215	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
CMHMHKIO_01249	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
CMHMHKIO_01250	4.68e-300	-	-	-	-	-	-	-	-
CMHMHKIO_01251	3.07e-124	-	-	-	-	-	-	-	-
CMHMHKIO_01252	1.19e-234	-	-	-	M	-	-	-	Peptidase_C39 like family
CMHMHKIO_01253	1.12e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CMHMHKIO_01254	6.86e-182	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CMHMHKIO_01255	4.89e-186	-	-	-	S	-	-	-	Cell surface protein
CMHMHKIO_01257	0.0	-	-	-	N	-	-	-	domain, Protein
CMHMHKIO_01258	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMHMHKIO_01259	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMHMHKIO_01260	7.44e-193	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
CMHMHKIO_01261	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
CMHMHKIO_01262	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CMHMHKIO_01263	1.48e-220	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
CMHMHKIO_01264	3.64e-134	-	-	-	-	-	-	-	-
CMHMHKIO_01265	3.61e-218	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
CMHMHKIO_01266	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CMHMHKIO_01267	4.8e-109	yvbK	-	-	K	-	-	-	GNAT family
CMHMHKIO_01268	1.45e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
CMHMHKIO_01269	2.27e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CMHMHKIO_01270	6.23e-303	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
CMHMHKIO_01271	1.15e-261	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMHMHKIO_01272	1.16e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMHMHKIO_01273	3.79e-136	-	-	-	-	-	-	-	-
CMHMHKIO_01274	6.04e-137	-	-	-	-	-	-	-	-
CMHMHKIO_01275	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMHMHKIO_01276	7.87e-144	vanZ	-	-	V	-	-	-	VanZ like family
CMHMHKIO_01277	4.66e-196	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
CMHMHKIO_01278	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
CMHMHKIO_01279	8.38e-186	-	-	-	S	-	-	-	Domain of unknown function DUF1829
CMHMHKIO_01280	2.12e-63	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
CMHMHKIO_01282	1.69e-197	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
CMHMHKIO_01283	2.7e-103	-	-	-	S	-	-	-	Pfam Transposase IS66
CMHMHKIO_01287	3.98e-91	-	-	-	-	-	-	-	-
CMHMHKIO_01288	7.89e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMHMHKIO_01289	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_01290	2.92e-108	-	-	-	K	-	-	-	MerR HTH family regulatory protein
CMHMHKIO_01291	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CMHMHKIO_01292	6.46e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
CMHMHKIO_01293	1.89e-157	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
CMHMHKIO_01294	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
CMHMHKIO_01295	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CMHMHKIO_01296	2.3e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CMHMHKIO_01297	9.15e-45	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
CMHMHKIO_01298	3.37e-183	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMHMHKIO_01299	4.57e-124	-	-	-	F	-	-	-	NUDIX domain
CMHMHKIO_01301	6.11e-278	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMHMHKIO_01302	1.64e-263	-	-	-	V	-	-	-	Abi-like protein
CMHMHKIO_01303	1.68e-94	-	-	-	-	-	-	-	-
CMHMHKIO_01304	4.14e-15	-	-	-	-	-	-	-	-
CMHMHKIO_01305	1.09e-23	-	-	-	-	-	-	-	-
CMHMHKIO_01307	0.000185	-	-	-	K	-	-	-	sequence-specific DNA binding
CMHMHKIO_01309	1.01e-163	-	-	-	K	-	-	-	Transcriptional regulator
CMHMHKIO_01311	3.74e-52	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
CMHMHKIO_01314	4.78e-217	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
CMHMHKIO_01316	1.65e-210	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
CMHMHKIO_01317	2.43e-49	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
CMHMHKIO_01318	1.64e-178	-	-	-	L	-	-	-	Transcriptional regulator
CMHMHKIO_01319	1.57e-197	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
CMHMHKIO_01321	2.14e-58	-	-	-	-	-	-	-	-
CMHMHKIO_01323	7.92e-135	-	-	-	S	-	-	-	HNH endonuclease
CMHMHKIO_01324	2.31e-97	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
CMHMHKIO_01325	2.83e-53	-	-	-	-	-	-	-	-
CMHMHKIO_01327	1.93e-105	-	-	-	-	-	-	-	-
CMHMHKIO_01328	1.57e-91	-	-	-	V	-	-	-	HNH endonuclease
CMHMHKIO_01329	1.25e-200	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
CMHMHKIO_01334	6.78e-42	-	-	-	-	-	-	-	-
CMHMHKIO_01335	1.71e-283	-	-	-	-	-	-	-	-
CMHMHKIO_01336	5.11e-312	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
CMHMHKIO_01339	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
CMHMHKIO_01340	0.0	-	-	-	S	-	-	-	domain, Protein
CMHMHKIO_01342	1.77e-137	-	-	-	-	-	-	-	-
CMHMHKIO_01343	0.0	-	-	-	S	-	-	-	COG0433 Predicted ATPase
CMHMHKIO_01344	2.45e-244	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	cysteine-type peptidase activity
CMHMHKIO_01349	0.000934	-	-	-	S	-	-	-	Ribbon-helix-helix protein, copG family
CMHMHKIO_01351	4.83e-295	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
CMHMHKIO_01353	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
CMHMHKIO_01355	1.05e-88	-	-	-	-	-	-	-	-
CMHMHKIO_01356	4.79e-21	-	-	-	-	-	-	-	-
CMHMHKIO_01357	3.24e-64	-	-	-	-	-	-	-	-
CMHMHKIO_01358	3.16e-23	-	-	-	-	-	-	-	-
CMHMHKIO_01360	1.72e-103	-	-	-	-	-	-	-	-
CMHMHKIO_01361	4.66e-200	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
CMHMHKIO_01363	1.56e-154	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CMHMHKIO_01365	1.1e-155	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
CMHMHKIO_01366	2.84e-62	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMHMHKIO_01367	2.98e-216	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMHMHKIO_01368	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CMHMHKIO_01369	1.68e-183	-	-	-	-	-	-	-	-
CMHMHKIO_01370	2.28e-276	-	-	-	S	-	-	-	Membrane
CMHMHKIO_01371	6.76e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
CMHMHKIO_01372	6.43e-66	-	-	-	-	-	-	-	-
CMHMHKIO_01373	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CMHMHKIO_01374	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CMHMHKIO_01375	2.5e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
CMHMHKIO_01376	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
CMHMHKIO_01378	1.73e-305	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
CMHMHKIO_01379	1.86e-245	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CMHMHKIO_01380	6.98e-53	-	-	-	-	-	-	-	-
CMHMHKIO_01381	1.22e-112	-	-	-	-	-	-	-	-
CMHMHKIO_01382	6.71e-34	-	-	-	-	-	-	-	-
CMHMHKIO_01383	1.72e-213	-	-	-	EG	-	-	-	EamA-like transporter family
CMHMHKIO_01384	2.96e-145	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
CMHMHKIO_01385	9.59e-101	usp5	-	-	T	-	-	-	universal stress protein
CMHMHKIO_01386	3.25e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
CMHMHKIO_01387	6.37e-187	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CMHMHKIO_01388	6.69e-287	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
CMHMHKIO_01389	1.54e-84	-	-	-	-	-	-	-	-
CMHMHKIO_01390	4.13e-94	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
CMHMHKIO_01391	7.56e-208	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
CMHMHKIO_01392	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
CMHMHKIO_01393	2.93e-133	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
CMHMHKIO_01394	7.01e-286	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
CMHMHKIO_01395	8.31e-234	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CMHMHKIO_01396	1.14e-276	-	-	-	M	-	-	-	Glycosyl transferases group 1
CMHMHKIO_01397	3.79e-295	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
CMHMHKIO_01398	3.75e-165	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
CMHMHKIO_01399	1.43e-186	epsB	-	-	M	-	-	-	biosynthesis protein
CMHMHKIO_01400	3.68e-170	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
CMHMHKIO_01401	4.2e-106	ccl	-	-	S	-	-	-	QueT transporter
CMHMHKIO_01402	4.62e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
CMHMHKIO_01403	2.1e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
CMHMHKIO_01404	6.56e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
CMHMHKIO_01405	1.07e-151	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
CMHMHKIO_01406	3.15e-230	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMHMHKIO_01407	4.99e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMHMHKIO_01408	3.01e-227	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMHMHKIO_01409	1.4e-208	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMHMHKIO_01410	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMHMHKIO_01411	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMHMHKIO_01412	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
CMHMHKIO_01413	1.4e-173	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
CMHMHKIO_01414	1.29e-233	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
CMHMHKIO_01415	4.97e-220	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
CMHMHKIO_01416	1.08e-63	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_01417	8.68e-106	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_01418	4.44e-224	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
CMHMHKIO_01419	3.15e-103	ptsN	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
CMHMHKIO_01420	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
CMHMHKIO_01421	1.91e-303	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
CMHMHKIO_01422	0.0	-	-	-	K	ko:K19505	-	ko00000,ko03000	Sigma-54 interaction domain
CMHMHKIO_01423	8.5e-91	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_01424	1.12e-116	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_01425	3.94e-173	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_01426	1.23e-193	-	-	-	G	ko:K02796,ko:K17467	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
CMHMHKIO_01427	2.85e-205	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
CMHMHKIO_01428	2.91e-175	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
CMHMHKIO_01429	2.36e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
CMHMHKIO_01430	7.79e-301	dcuC	-	-	C	ko:K03326	-	ko00000,ko02000	Tripartite ATP-independent periplasmic transporter, DctM component
CMHMHKIO_01431	4.26e-221	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
CMHMHKIO_01432	1.91e-253	ydeM3	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
CMHMHKIO_01433	2.97e-170	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
CMHMHKIO_01434	8.68e-211	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
CMHMHKIO_01435	9.57e-14	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
CMHMHKIO_01436	2.4e-20	licR	-	-	G	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_01437	3.46e-207	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
CMHMHKIO_01438	0.0	-	-	-	G	-	-	-	FGGY family of carbohydrate kinases, C-terminal domain
CMHMHKIO_01439	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CMHMHKIO_01440	9.89e-64	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_01441	6.52e-103	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_01442	2.63e-206	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
CMHMHKIO_01443	1.97e-173	farR	-	-	K	-	-	-	Helix-turn-helix domain
CMHMHKIO_01444	1.66e-116	-	-	-	M	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CMHMHKIO_01445	2.16e-132	laaE	-	-	K	-	-	-	Transcriptional regulator PadR-like family
CMHMHKIO_01446	0.0	chaT1	-	-	U	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
CMHMHKIO_01447	2.75e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_01448	3.62e-121	yveA	-	-	Q	-	-	-	Isochorismatase family
CMHMHKIO_01449	9.53e-76	ps105	-	-	-	-	-	-	-
CMHMHKIO_01451	5.38e-125	-	-	-	K	-	-	-	Helix-turn-helix domain
CMHMHKIO_01452	3.37e-140	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
CMHMHKIO_01453	3.87e-97	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMHMHKIO_01454	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMHMHKIO_01455	2.92e-192	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_01456	3.19e-211	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
CMHMHKIO_01457	7.33e-271	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
CMHMHKIO_01458	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMHMHKIO_01459	1.89e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
CMHMHKIO_01460	3.28e-175	-	-	-	F	-	-	-	NUDIX domain
CMHMHKIO_01461	1.45e-187	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
CMHMHKIO_01462	9.61e-247	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
CMHMHKIO_01463	1.13e-251	-	-	-	V	-	-	-	Beta-lactamase
CMHMHKIO_01464	1.43e-197	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CMHMHKIO_01465	1.58e-211	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CMHMHKIO_01466	1.67e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_01467	1.56e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_01468	8.76e-177	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_01469	1.06e-259	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
CMHMHKIO_01470	2.28e-220	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
CMHMHKIO_01471	1.18e-134	-	-	-	Q	-	-	-	Methyltransferase
CMHMHKIO_01472	2.16e-68	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
CMHMHKIO_01473	2.69e-22	-	-	-	-	-	-	-	-
CMHMHKIO_01474	2.45e-59	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
CMHMHKIO_01475	3.22e-65	-	-	-	S	-	-	-	alpha beta
CMHMHKIO_01476	3.81e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
CMHMHKIO_01477	5.44e-174	-	-	-	S	-	-	-	-acetyltransferase
CMHMHKIO_01478	1.17e-121	yfbM	-	-	K	-	-	-	FR47-like protein
CMHMHKIO_01479	2.42e-122	-	-	-	E	-	-	-	HAD-hyrolase-like
CMHMHKIO_01480	4.93e-244	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
CMHMHKIO_01481	8.05e-180	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CMHMHKIO_01482	1.7e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_01483	5.73e-110	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CMHMHKIO_01484	2.61e-105	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CMHMHKIO_01485	8.99e-300	-	-	-	K	-	-	-	Putative DNA-binding domain
CMHMHKIO_01486	1.06e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
CMHMHKIO_01487	1.74e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMHMHKIO_01488	9.37e-255	ysdE	-	-	P	-	-	-	Citrate transporter
CMHMHKIO_01489	8.69e-91	-	-	-	-	-	-	-	-
CMHMHKIO_01490	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
CMHMHKIO_01491	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMHMHKIO_01493	2.96e-134	-	-	-	-	-	-	-	-
CMHMHKIO_01494	0.0	cadA	-	-	P	-	-	-	P-type ATPase
CMHMHKIO_01495	2.19e-100	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CMHMHKIO_01496	2.35e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
CMHMHKIO_01497	1.7e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
CMHMHKIO_01499	4.32e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
CMHMHKIO_01500	1.05e-182	yycI	-	-	S	-	-	-	YycH protein
CMHMHKIO_01501	0.0	yycH	-	-	S	-	-	-	YycH protein
CMHMHKIO_01502	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMHMHKIO_01503	3.03e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CMHMHKIO_01504	1.06e-157	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
CMHMHKIO_01505	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CMHMHKIO_01506	1.39e-299	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
CMHMHKIO_01507	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
CMHMHKIO_01508	4.78e-273	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
CMHMHKIO_01509	9.09e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
CMHMHKIO_01510	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHMHKIO_01511	1.97e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
CMHMHKIO_01512	5.01e-69	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_01513	8.36e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
CMHMHKIO_01514	1.82e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_01515	1.84e-110	-	-	-	F	-	-	-	NUDIX domain
CMHMHKIO_01516	1.35e-119	-	-	-	S	-	-	-	AAA domain
CMHMHKIO_01517	3.32e-148	ycaC	-	-	Q	-	-	-	Isochorismatase family
CMHMHKIO_01518	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMHMHKIO_01519	1.38e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
CMHMHKIO_01520	2.11e-220	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
CMHMHKIO_01521	1.08e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
CMHMHKIO_01522	1.73e-216	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
CMHMHKIO_01523	1.57e-171	manM	-	-	G	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
CMHMHKIO_01524	1.44e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_01525	9.77e-279	-	-	-	EGP	-	-	-	Major facilitator Superfamily
CMHMHKIO_01526	1.31e-245	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
CMHMHKIO_01527	8.33e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMHMHKIO_01528	6.17e-204	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
CMHMHKIO_01530	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_01531	6.58e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_01532	4.51e-41	-	-	-	-	-	-	-	-
CMHMHKIO_01533	2.97e-305	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMHMHKIO_01534	1.33e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
CMHMHKIO_01535	2.15e-21	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
CMHMHKIO_01536	1.4e-69	-	-	-	-	-	-	-	-
CMHMHKIO_01537	6.11e-106	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
CMHMHKIO_01538	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
CMHMHKIO_01539	7.76e-186	-	-	-	S	-	-	-	AAA ATPase domain
CMHMHKIO_01540	5.81e-217	-	-	-	G	-	-	-	Phosphotransferase enzyme family
CMHMHKIO_01541	1.09e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_01542	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_01543	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_01544	9.37e-129	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CMHMHKIO_01545	7.75e-138	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
CMHMHKIO_01546	1.51e-90	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
CMHMHKIO_01547	6.74e-112	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
CMHMHKIO_01548	5.5e-238	-	-	-	S	-	-	-	Protein of unknown function DUF58
CMHMHKIO_01549	1.77e-51	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
CMHMHKIO_01550	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
CMHMHKIO_01551	2.11e-273	-	-	-	M	-	-	-	Glycosyl transferases group 1
CMHMHKIO_01552	1.34e-126	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CMHMHKIO_01553	9.44e-190	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
CMHMHKIO_01554	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
CMHMHKIO_01555	8.59e-149	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
CMHMHKIO_01556	4.66e-30	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
CMHMHKIO_01557	1.09e-273	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
CMHMHKIO_01558	5.39e-292	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
CMHMHKIO_01559	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
CMHMHKIO_01560	1.62e-159	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
CMHMHKIO_01561	6.61e-196	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
CMHMHKIO_01562	5.33e-124	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
CMHMHKIO_01563	1.58e-86	-	-	-	-	-	-	-	-
CMHMHKIO_01564	2.35e-286	yagE	-	-	E	-	-	-	Amino acid permease
CMHMHKIO_01565	7.05e-219	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CMHMHKIO_01566	3.09e-212	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMHMHKIO_01567	2.54e-55	-	-	-	L	-	-	-	DNA integration
CMHMHKIO_01568	6.37e-144	-	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
CMHMHKIO_01570	7.41e-45	-	-	-	-	-	-	-	-
CMHMHKIO_01571	5.45e-26	-	-	-	-	-	-	-	-
CMHMHKIO_01572	3.31e-39	-	-	-	-	-	-	-	-
CMHMHKIO_01574	7.72e-35	-	-	-	-	-	-	-	-
CMHMHKIO_01575	1.64e-205	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
CMHMHKIO_01576	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
CMHMHKIO_01577	9.69e-72	-	-	-	S	-	-	-	Phage head-tail joining protein
CMHMHKIO_01579	1.06e-28	-	-	-	L	-	-	-	HNH endonuclease
CMHMHKIO_01580	9.78e-107	terS	-	-	L	-	-	-	Phage terminase, small subunit
CMHMHKIO_01581	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
CMHMHKIO_01582	3e-29	-	-	-	-	-	-	-	-
CMHMHKIO_01583	5.1e-284	-	-	-	S	-	-	-	Phage portal protein
CMHMHKIO_01584	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
CMHMHKIO_01585	8.23e-62	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
CMHMHKIO_01586	2.3e-23	-	-	-	-	-	-	-	-
CMHMHKIO_01587	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
CMHMHKIO_01589	3.23e-218	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMHMHKIO_01590	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
CMHMHKIO_01591	5.29e-239	lipA	-	-	I	-	-	-	Carboxylesterase family
CMHMHKIO_01592	1.68e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
CMHMHKIO_01593	9.2e-101	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHMHKIO_01594	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
CMHMHKIO_01595	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_01596	2.05e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMHMHKIO_01597	3.86e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
CMHMHKIO_01598	8.43e-59	-	-	-	-	-	-	-	-
CMHMHKIO_01599	6.72e-19	-	-	-	-	-	-	-	-
CMHMHKIO_01600	3.71e-239	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMHMHKIO_01601	7.13e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_01602	2.53e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CMHMHKIO_01603	1.77e-220	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
CMHMHKIO_01604	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
CMHMHKIO_01605	3.28e-257	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
CMHMHKIO_01606	5.35e-289	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
CMHMHKIO_01607	1.48e-104	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CMHMHKIO_01608	3.8e-175	labL	-	-	S	-	-	-	Putative threonine/serine exporter
CMHMHKIO_01610	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CMHMHKIO_01611	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CMHMHKIO_01613	1.73e-171	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
CMHMHKIO_01614	4.53e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMHMHKIO_01615	2.99e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CMHMHKIO_01616	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
CMHMHKIO_01617	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMHMHKIO_01618	1.02e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMHMHKIO_01620	4.07e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
CMHMHKIO_01621	9.09e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMHMHKIO_01622	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMHMHKIO_01623	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMHMHKIO_01624	5.22e-163	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CMHMHKIO_01625	5.2e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMHMHKIO_01626	1.36e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
CMHMHKIO_01627	7.5e-111	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMHMHKIO_01628	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMHMHKIO_01629	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CMHMHKIO_01631	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
CMHMHKIO_01632	8.08e-229	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
CMHMHKIO_01633	1.21e-48	-	-	-	-	-	-	-	-
CMHMHKIO_01634	9.81e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CMHMHKIO_01637	5.26e-183	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMHMHKIO_01641	4.92e-201	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
CMHMHKIO_01642	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CMHMHKIO_01643	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_01644	4.12e-128	-	-	-	K	-	-	-	transcriptional regulator
CMHMHKIO_01645	4.35e-197	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMHMHKIO_01646	4.92e-65	-	-	-	-	-	-	-	-
CMHMHKIO_01649	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
CMHMHKIO_01650	2.08e-188	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CMHMHKIO_01651	6.97e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CMHMHKIO_01652	8.19e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
CMHMHKIO_01653	3.29e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_01655	2.37e-306	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CMHMHKIO_01657	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CMHMHKIO_01658	1.02e-144	-	-	-	S	-	-	-	Membrane
CMHMHKIO_01659	4.98e-68	-	-	-	-	-	-	-	-
CMHMHKIO_01661	4.32e-133	-	-	-	-	-	-	-	-
CMHMHKIO_01662	2.3e-101	-	-	-	-	-	-	-	-
CMHMHKIO_01663	4.97e-70	-	-	-	-	-	-	-	-
CMHMHKIO_01664	1.95e-159	azlC	-	-	E	-	-	-	branched-chain amino acid
CMHMHKIO_01665	1.83e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
CMHMHKIO_01667	2.44e-40	-	-	-	-	-	-	-	-
CMHMHKIO_01668	2.25e-185	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMHMHKIO_01669	1.19e-150	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
CMHMHKIO_01674	1.44e-61	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
CMHMHKIO_01675	6.87e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
CMHMHKIO_01676	1.3e-154	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
CMHMHKIO_01677	1.74e-21	-	-	-	-	-	-	-	-
CMHMHKIO_01678	1.47e-33	-	-	-	-	-	-	-	-
CMHMHKIO_01679	2.54e-21	-	-	-	U	-	-	-	PrgI family protein
CMHMHKIO_01680	6.91e-314	-	-	-	U	-	-	-	AAA-like domain
CMHMHKIO_01681	8.57e-43	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
CMHMHKIO_01685	1.21e-74	-	-	-	L	-	-	-	IrrE N-terminal-like domain
CMHMHKIO_01688	1.03e-08	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
CMHMHKIO_01689	4e-112	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
CMHMHKIO_01690	2.74e-81	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
CMHMHKIO_01691	6.75e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CMHMHKIO_01692	2.83e-152	-	-	-	GM	-	-	-	NmrA-like family
CMHMHKIO_01693	5.94e-148	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
CMHMHKIO_01694	7.04e-102	-	-	-	-	-	-	-	-
CMHMHKIO_01695	0.0	-	-	-	M	-	-	-	domain protein
CMHMHKIO_01696	1.26e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CMHMHKIO_01697	2.1e-27	-	-	-	-	-	-	-	-
CMHMHKIO_01698	8.26e-104	-	-	-	-	-	-	-	-
CMHMHKIO_01700	0.0	-	-	-	L	-	-	-	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CMHMHKIO_01701	6.39e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMHMHKIO_01702	1.58e-91	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMHMHKIO_01704	1.72e-49	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	phosphopyruvate hydratase activity
CMHMHKIO_01705	1.99e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
CMHMHKIO_01706	1.49e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CMHMHKIO_01707	2.46e-174	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_01708	1.97e-188	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_01709	6.45e-91	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CMHMHKIO_01710	9.65e-163	-	-	-	-	-	-	-	-
CMHMHKIO_01711	8.53e-139	-	-	-	-	-	-	-	-
CMHMHKIO_01712	1.17e-173	-	-	-	-	-	-	-	-
CMHMHKIO_01713	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
CMHMHKIO_01714	7.29e-267	-	-	-	GKT	-	-	-	transcriptional antiterminator
CMHMHKIO_01715	1.7e-224	-	-	-	GKT	-	-	-	transcriptional antiterminator
CMHMHKIO_01716	4.1e-67	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_01717	6.84e-293	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CMHMHKIO_01718	2.22e-93	-	-	-	-	-	-	-	-
CMHMHKIO_01719	6.47e-208	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
CMHMHKIO_01720	1.4e-152	-	-	-	S	-	-	-	Zeta toxin
CMHMHKIO_01721	3.2e-203	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
CMHMHKIO_01722	9.64e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
CMHMHKIO_01723	5.02e-230	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
CMHMHKIO_01724	1.91e-191	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
CMHMHKIO_01729	4.63e-309	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
CMHMHKIO_01731	2.37e-91	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
CMHMHKIO_01732	5.11e-93	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
CMHMHKIO_01733	2.13e-194	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
CMHMHKIO_01734	6.93e-110	-	-	-	-	-	-	-	-
CMHMHKIO_01736	7.42e-230	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CMHMHKIO_01737	1.22e-181	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_01738	3.24e-167	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_01739	6.11e-229	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
CMHMHKIO_01740	2.78e-25	-	-	-	L	ko:K07483	-	ko00000	transposase activity
CMHMHKIO_01741	1e-205	-	-	-	LM	-	-	-	gp58-like protein
CMHMHKIO_01742	2.91e-94	-	-	-	-	-	-	-	-
CMHMHKIO_01743	1.62e-53	-	-	-	-	-	-	-	-
CMHMHKIO_01744	5.45e-86	-	-	-	-	-	-	-	-
CMHMHKIO_01746	6.86e-92	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
CMHMHKIO_01747	1.51e-261	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
CMHMHKIO_01749	5.52e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
CMHMHKIO_01750	2.1e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMHMHKIO_01751	2.16e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
CMHMHKIO_01752	2.81e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CMHMHKIO_01753	2.11e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMHMHKIO_01754	6.34e-294	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
CMHMHKIO_01755	1.33e-63	-	-	-	-	-	-	-	-
CMHMHKIO_01757	4.68e-53	-	-	-	-	-	-	-	-
CMHMHKIO_01758	2.66e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
CMHMHKIO_01759	1.64e-237	yveB	-	-	I	-	-	-	PAP2 superfamily
CMHMHKIO_01760	2.35e-269	mccF	-	-	V	-	-	-	LD-carboxypeptidase
CMHMHKIO_01761	6.55e-57	-	-	-	-	-	-	-	-
CMHMHKIO_01762	2.61e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
CMHMHKIO_01763	2.47e-117	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
CMHMHKIO_01764	1.17e-245	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMHMHKIO_01765	1.21e-59	-	-	-	-	-	-	-	-
CMHMHKIO_01766	2.74e-112	-	-	-	K	-	-	-	Transcriptional regulator
CMHMHKIO_01767	1.07e-239	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	alcohol dehydrogenase
CMHMHKIO_01768	1.61e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
CMHMHKIO_01769	2.42e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
CMHMHKIO_01770	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
CMHMHKIO_01771	5.52e-61	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
CMHMHKIO_01772	8.3e-123	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
CMHMHKIO_01773	0.0	ybeC	-	-	E	-	-	-	amino acid
CMHMHKIO_01774	1.09e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CMHMHKIO_01775	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CMHMHKIO_01776	1.58e-220	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMHMHKIO_01778	1.63e-279	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CMHMHKIO_01779	1.52e-57	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
CMHMHKIO_01780	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMHMHKIO_01781	8.92e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
CMHMHKIO_01782	1.21e-98	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_01783	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_01784	2.7e-291	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
CMHMHKIO_01785	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_01786	0.0	-	-	-	K	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_01787	8.51e-204	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
CMHMHKIO_01788	0.0	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMHMHKIO_01789	1.23e-176	-	-	-	K	-	-	-	DeoR C terminal sensor domain
CMHMHKIO_01791	7.74e-68	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
CMHMHKIO_01792	9.14e-129	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
CMHMHKIO_01793	1.35e-192	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMHMHKIO_01794	2.09e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMHMHKIO_01795	8.4e-150	-	-	-	-	-	-	-	-
CMHMHKIO_01797	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMHMHKIO_01798	8.37e-108	-	-	-	L	-	-	-	Transposase DDE domain
CMHMHKIO_01799	1.16e-248	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CMHMHKIO_01800	2.22e-212	-	-	-	LM	-	-	-	gp58-like protein
CMHMHKIO_01801	2.91e-94	-	-	-	-	-	-	-	-
CMHMHKIO_01802	2.21e-51	-	-	-	-	-	-	-	-
CMHMHKIO_01803	4.88e-59	-	-	-	-	-	-	-	-
CMHMHKIO_01804	2.93e-75	hol	-	-	S	-	-	-	Bacteriophage holin
CMHMHKIO_01806	3.23e-252	-	-	-	M	-	-	-	Bacteriophage peptidoglycan hydrolase
CMHMHKIO_01807	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CMHMHKIO_01808	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CMHMHKIO_01809	9.78e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
CMHMHKIO_01812	7.73e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
CMHMHKIO_01813	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
CMHMHKIO_01814	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMHMHKIO_01815	5.11e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CMHMHKIO_01816	1.59e-210	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMHMHKIO_01818	4.22e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
CMHMHKIO_01819	1.18e-250	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
CMHMHKIO_01820	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CMHMHKIO_01821	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMHMHKIO_01822	1.38e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CMHMHKIO_01823	2.68e-310	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMHMHKIO_01824	1.17e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
CMHMHKIO_01825	7.17e-87	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
CMHMHKIO_01826	1.99e-53	yabO	-	-	J	-	-	-	S4 domain protein
CMHMHKIO_01827	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CMHMHKIO_01828	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMHMHKIO_01829	4.28e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CMHMHKIO_01830	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CMHMHKIO_01831	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
CMHMHKIO_01832	4.14e-126	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
CMHMHKIO_01833	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
CMHMHKIO_01834	2.45e-150	-	-	-	S	-	-	-	Flavodoxin-like fold
CMHMHKIO_01835	3.08e-124	-	-	-	S	-	-	-	(CBS) domain
CMHMHKIO_01836	1.02e-169	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CMHMHKIO_01837	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
CMHMHKIO_01838	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
CMHMHKIO_01839	1.39e-112	queT	-	-	S	-	-	-	QueT transporter
CMHMHKIO_01840	5.68e-83	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
CMHMHKIO_01841	1.9e-43	-	-	-	-	-	-	-	-
CMHMHKIO_01842	2.8e-278	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMHMHKIO_01843	2.63e-82	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CMHMHKIO_01844	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CMHMHKIO_01845	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CMHMHKIO_01846	2.07e-188	-	-	-	-	-	-	-	-
CMHMHKIO_01847	3.18e-161	-	-	-	S	-	-	-	Tetratricopeptide repeat
CMHMHKIO_01848	2.61e-163	-	-	-	-	-	-	-	-
CMHMHKIO_01849	2.29e-87	-	-	-	-	-	-	-	-
CMHMHKIO_01850	2.28e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
CMHMHKIO_01851	1.64e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMHMHKIO_01852	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CMHMHKIO_01853	3.42e-202	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CMHMHKIO_01854	1.15e-111	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CMHMHKIO_01855	4.23e-104	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
CMHMHKIO_01856	2.07e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
CMHMHKIO_01857	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
CMHMHKIO_01858	3.75e-40	mutT	3.5.4.33, 3.6.1.13, 3.6.1.55	-	L	ko:K01515,ko:K03574,ko:K11991	ko00230,map00230	ko00000,ko00001,ko01000,ko03016,ko03400	nUDIX hydrolase
CMHMHKIO_01859	2.14e-237	-	-	-	S	-	-	-	DUF218 domain
CMHMHKIO_01860	1.31e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CMHMHKIO_01861	1.68e-104	-	-	-	E	-	-	-	glutamate:sodium symporter activity
CMHMHKIO_01862	1.32e-74	nudA	-	-	S	-	-	-	ASCH
CMHMHKIO_01863	1.81e-35	-	-	-	-	-	-	-	-
CMHMHKIO_01864	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMHMHKIO_01865	3.29e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMHMHKIO_01866	1.79e-286	ysaA	-	-	V	-	-	-	RDD family
CMHMHKIO_01867	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
CMHMHKIO_01868	2.24e-155	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_01869	8.36e-158	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
CMHMHKIO_01870	1.4e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
CMHMHKIO_01871	6.63e-232	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CMHMHKIO_01872	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
CMHMHKIO_01873	1.75e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CMHMHKIO_01874	6.78e-130	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CMHMHKIO_01875	9.1e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
CMHMHKIO_01876	2.57e-104	manR	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
CMHMHKIO_01877	1.35e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
CMHMHKIO_01878	1.49e-221	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
CMHMHKIO_01879	8.65e-162	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
CMHMHKIO_01880	5.31e-211	-	-	-	T	-	-	-	GHKL domain
CMHMHKIO_01881	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CMHMHKIO_01882	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CMHMHKIO_01883	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMHMHKIO_01884	4.11e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CMHMHKIO_01885	1.25e-197	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
CMHMHKIO_01886	1.09e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
CMHMHKIO_01887	3.11e-218	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CMHMHKIO_01888	9.14e-139	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CMHMHKIO_01889	5.67e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
CMHMHKIO_01890	6.41e-24	-	-	-	-	-	-	-	-
CMHMHKIO_01891	5.59e-220	-	-	-	-	-	-	-	-
CMHMHKIO_01893	3.21e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
CMHMHKIO_01894	4.7e-50	-	-	-	-	-	-	-	-
CMHMHKIO_01895	4.34e-196	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
CMHMHKIO_01896	2.57e-223	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CMHMHKIO_01897	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CMHMHKIO_01898	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CMHMHKIO_01899	1.74e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
CMHMHKIO_01900	5.94e-198	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
CMHMHKIO_01901	2.76e-120	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
CMHMHKIO_01902	9.66e-307	dinF	-	-	V	-	-	-	MatE
CMHMHKIO_01903	8.78e-158	-	-	-	S	ko:K06872	-	ko00000	TPM domain
CMHMHKIO_01904	8.42e-135	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
CMHMHKIO_01905	1.48e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CMHMHKIO_01906	5.94e-262	-	-	-	V	-	-	-	efflux transmembrane transporter activity
CMHMHKIO_01907	1.95e-225	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
CMHMHKIO_01909	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
CMHMHKIO_01910	6.07e-225	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_01911	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CMHMHKIO_01913	0.0	-	-	-	L	-	-	-	DNA helicase
CMHMHKIO_01914	2.93e-195	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
CMHMHKIO_01915	1.6e-222	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
CMHMHKIO_01916	5.68e-148	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMHMHKIO_01918	3.62e-149	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CMHMHKIO_01919	1.91e-93	-	-	-	K	-	-	-	MarR family
CMHMHKIO_01920	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
CMHMHKIO_01921	7.61e-247	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
CMHMHKIO_01922	5.86e-187	-	-	-	S	-	-	-	hydrolase
CMHMHKIO_01923	4.04e-79	-	-	-	-	-	-	-	-
CMHMHKIO_01924	4.9e-17	-	-	-	-	-	-	-	-
CMHMHKIO_01925	3.55e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
CMHMHKIO_01926	1.63e-163	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
CMHMHKIO_01927	5.08e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
CMHMHKIO_01928	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMHMHKIO_01929	1.08e-213	-	-	-	K	-	-	-	LysR substrate binding domain
CMHMHKIO_01930	6.04e-291	-	-	-	EK	-	-	-	Aminotransferase, class I
CMHMHKIO_01931	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_01932	8.61e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_01933	2.13e-246	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMHMHKIO_01934	4.42e-154	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
CMHMHKIO_01935	5.24e-116	-	-	-	-	-	-	-	-
CMHMHKIO_01936	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_01937	1.88e-223	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
CMHMHKIO_01938	2.36e-167	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CMHMHKIO_01939	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CMHMHKIO_01940	5.44e-175	-	-	-	K	-	-	-	UTRA domain
CMHMHKIO_01941	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
CMHMHKIO_01942	1.72e-216	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_01943	9.8e-169	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_01944	2.84e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_01945	5.34e-64	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
CMHMHKIO_01946	5.16e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_01947	0.0	bgl	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMHMHKIO_01948	1.77e-203	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CMHMHKIO_01949	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
CMHMHKIO_01950	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
CMHMHKIO_01951	1.54e-307	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHMHKIO_01952	1.9e-173	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
CMHMHKIO_01954	3.7e-176	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
CMHMHKIO_01956	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CMHMHKIO_01957	4.54e-70	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_01958	1.89e-110	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_01959	1.62e-186	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
CMHMHKIO_01960	4.06e-209	-	-	-	J	-	-	-	Methyltransferase domain
CMHMHKIO_01961	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CMHMHKIO_01964	3.65e-46	-	-	-	M	-	-	-	Right handed beta helix region
CMHMHKIO_01965	0.0	-	-	-	M	-	-	-	Right handed beta helix region
CMHMHKIO_01966	3.76e-96	-	-	-	-	-	-	-	-
CMHMHKIO_01967	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
CMHMHKIO_01969	5.89e-108	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_01970	8.63e-185	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_01971	6.84e-186	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_01972	1.72e-114	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_01973	8.01e-301	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
CMHMHKIO_01974	1.65e-205	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CMHMHKIO_01975	1.1e-179	-	-	-	K	-	-	-	Bacterial transcriptional regulator
CMHMHKIO_01976	4.76e-212	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CMHMHKIO_01977	6.38e-193	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMHMHKIO_01978	2.32e-153	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
CMHMHKIO_01979	3.36e-248	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
CMHMHKIO_01980	4.7e-156	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
CMHMHKIO_01981	8.71e-164	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CMHMHKIO_01982	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CMHMHKIO_01983	2.46e-221	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
CMHMHKIO_01984	1.56e-154	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
CMHMHKIO_01985	8.38e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
CMHMHKIO_01986	1.8e-316	kinE	-	-	T	-	-	-	Histidine kinase
CMHMHKIO_01987	1.97e-162	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
CMHMHKIO_01988	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
CMHMHKIO_01989	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CMHMHKIO_01990	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
CMHMHKIO_01991	0.0	-	-	-	-	-	-	-	-
CMHMHKIO_01993	2.63e-27	-	-	-	-	-	-	-	-
CMHMHKIO_01995	2.08e-214	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
CMHMHKIO_01996	9.99e-25	-	-	-	-	-	-	-	-
CMHMHKIO_01998	5.81e-130	-	-	-	D	-	-	-	AAA domain
CMHMHKIO_01999	2.09e-101	repA	-	-	S	-	-	-	Replication initiator protein A
CMHMHKIO_02008	3.3e-315	xylP	-	-	G	-	-	-	MFS/sugar transport protein
CMHMHKIO_02009	3.33e-133	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
CMHMHKIO_02011	9.41e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
CMHMHKIO_02012	2.3e-169	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CMHMHKIO_02013	5.68e-91	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_02014	2.1e-114	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_02015	1.65e-184	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_02016	5.86e-190	-	-	-	G	-	-	-	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_02017	3.25e-224	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CMHMHKIO_02018	2.99e-122	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
CMHMHKIO_02019	2.93e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
CMHMHKIO_02020	6.02e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CMHMHKIO_02021	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
CMHMHKIO_02022	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
CMHMHKIO_02023	6.22e-102	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
CMHMHKIO_02024	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
CMHMHKIO_02025	4.31e-165	-	-	-	S	-	-	-	phage tail
CMHMHKIO_02027	7.31e-97	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CMHMHKIO_02028	1.69e-107	-	-	-	L	-	-	-	Transposase DDE domain
CMHMHKIO_02029	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMHMHKIO_02030	7.52e-87	repA	-	-	S	-	-	-	Replication initiator protein A
CMHMHKIO_02031	4.59e-58	-	-	-	-	-	-	-	-
CMHMHKIO_02032	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CMHMHKIO_02033	9.5e-312	-	-	-	D	-	-	-	Phage tail tape measure protein
CMHMHKIO_02034	1.5e-165	-	-	-	S	-	-	-	phage tail
CMHMHKIO_02036	2.08e-207	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
CMHMHKIO_02037	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
CMHMHKIO_02038	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMHMHKIO_02039	2.65e-67	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
CMHMHKIO_02040	5.71e-58	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
CMHMHKIO_02042	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMHMHKIO_02043	6e-269	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
CMHMHKIO_02044	3.74e-204	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
CMHMHKIO_02045	3.96e-224	-	-	-	I	-	-	-	Alpha/beta hydrolase family
CMHMHKIO_02046	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
CMHMHKIO_02047	8.3e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
CMHMHKIO_02048	2.04e-149	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
CMHMHKIO_02049	1.39e-233	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMHMHKIO_02050	1.9e-165	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
CMHMHKIO_02051	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMHMHKIO_02052	3.43e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
CMHMHKIO_02053	1.82e-265	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CMHMHKIO_02054	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMHMHKIO_02055	1.24e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMHMHKIO_02056	1.2e-87	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CMHMHKIO_02057	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CMHMHKIO_02058	4.47e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMHMHKIO_02059	4.17e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
CMHMHKIO_02060	8.99e-229	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMHMHKIO_02061	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMHMHKIO_02062	1.01e-157	csrR	-	-	K	-	-	-	response regulator
CMHMHKIO_02063	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CMHMHKIO_02064	1.9e-53	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CMHMHKIO_02065	3.82e-128	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
CMHMHKIO_02066	1.67e-270	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
CMHMHKIO_02067	8.74e-181	yccK	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
CMHMHKIO_02068	1.18e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CMHMHKIO_02069	1.31e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
CMHMHKIO_02070	5.06e-168	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMHMHKIO_02071	3.95e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
CMHMHKIO_02072	3.02e-262	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
CMHMHKIO_02073	6.63e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
CMHMHKIO_02074	4.11e-222	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMHMHKIO_02075	1.93e-243	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMHMHKIO_02076	2.14e-157	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
CMHMHKIO_02077	4.5e-233	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
CMHMHKIO_02078	1.01e-130	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
CMHMHKIO_02079	1.02e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMHMHKIO_02080	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
CMHMHKIO_02081	7.46e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMHMHKIO_02082	2.31e-167	-	-	-	S	-	-	-	SseB protein N-terminal domain
CMHMHKIO_02083	5.3e-70	-	-	-	-	-	-	-	-
CMHMHKIO_02084	4.61e-137	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
CMHMHKIO_02085	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMHMHKIO_02087	2.02e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
CMHMHKIO_02088	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
CMHMHKIO_02089	2.06e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMHMHKIO_02090	2.82e-132	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CMHMHKIO_02091	7.86e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CMHMHKIO_02092	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMHMHKIO_02093	4.41e-156	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
CMHMHKIO_02094	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
CMHMHKIO_02095	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CMHMHKIO_02096	5.48e-150	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMHMHKIO_02097	5.32e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
CMHMHKIO_02099	8.13e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CMHMHKIO_02100	4.51e-189	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
CMHMHKIO_02101	6.39e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_02102	2.4e-172	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_02103	1.67e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
CMHMHKIO_02104	2.44e-82	-	-	-	S	-	-	-	YtxH-like protein
CMHMHKIO_02105	5.26e-205	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMHMHKIO_02106	8.42e-232	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
CMHMHKIO_02107	1.03e-72	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
CMHMHKIO_02108	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
CMHMHKIO_02109	1.3e-198	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
CMHMHKIO_02110	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CMHMHKIO_02111	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
CMHMHKIO_02113	1.97e-88	-	-	-	-	-	-	-	-
CMHMHKIO_02114	4.04e-32	-	-	-	-	-	-	-	-
CMHMHKIO_02115	3.67e-227	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
CMHMHKIO_02116	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
CMHMHKIO_02117	3.53e-158	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CMHMHKIO_02118	1.13e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CMHMHKIO_02119	3.42e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
CMHMHKIO_02120	7.88e-121	traP	1.14.99.57, 6.2.1.3	-	S	ko:K01897,ko:K21481	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	heme oxygenase (decyclizing) activity
CMHMHKIO_02121	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
CMHMHKIO_02122	1.14e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_02123	1.57e-159	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
CMHMHKIO_02124	1.21e-266	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
CMHMHKIO_02125	1.54e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMHMHKIO_02126	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
CMHMHKIO_02127	2.87e-101	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
CMHMHKIO_02128	4.69e-301	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
CMHMHKIO_02129	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
CMHMHKIO_02130	2.36e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CMHMHKIO_02131	7.52e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
CMHMHKIO_02132	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMHMHKIO_02133	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMHMHKIO_02134	3.05e-168	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMHMHKIO_02135	7.25e-56	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMHMHKIO_02136	1.63e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
CMHMHKIO_02137	8.98e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMHMHKIO_02138	2.66e-102	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMHMHKIO_02139	6.68e-136	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
CMHMHKIO_02140	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CMHMHKIO_02141	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMHMHKIO_02142	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
CMHMHKIO_02143	9.5e-39	-	-	-	-	-	-	-	-
CMHMHKIO_02144	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
CMHMHKIO_02145	1.17e-61	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
CMHMHKIO_02147	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CMHMHKIO_02148	1.44e-311	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
CMHMHKIO_02149	4.17e-262	yueF	-	-	S	-	-	-	AI-2E family transporter
CMHMHKIO_02150	1.13e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
CMHMHKIO_02151	1.92e-123	-	-	-	-	-	-	-	-
CMHMHKIO_02152	1.1e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
CMHMHKIO_02153	3.39e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
CMHMHKIO_02154	0.0	frvR	-	-	K	ko:K02538,ko:K03483,ko:K09685,ko:K18531	-	ko00000,ko03000	transcriptional antiterminator
CMHMHKIO_02155	6.46e-83	-	-	-	-	-	-	-	-
CMHMHKIO_02156	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMHMHKIO_02157	4.13e-104	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
CMHMHKIO_02158	2.13e-172	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
CMHMHKIO_02159	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMHMHKIO_02160	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHMHKIO_02161	2.36e-111	-	-	-	-	-	-	-	-
CMHMHKIO_02162	1.94e-66	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
CMHMHKIO_02163	6.27e-67	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_02164	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CMHMHKIO_02165	2.6e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
CMHMHKIO_02166	1.63e-267	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
CMHMHKIO_02167	1.41e-265	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
CMHMHKIO_02168	7.23e-66	-	-	-	-	-	-	-	-
CMHMHKIO_02169	3.47e-207	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
CMHMHKIO_02170	4.44e-134	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
CMHMHKIO_02171	2.25e-201	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	converts alpha-aldose to the beta-anomer
CMHMHKIO_02172	1.88e-272	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CMHMHKIO_02173	4.33e-132	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CMHMHKIO_02175	1.4e-105	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
CMHMHKIO_02176	1.65e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
CMHMHKIO_02177	2.36e-167	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_02178	2.83e-188	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CMHMHKIO_02179	2.53e-48	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_02180	7.4e-165	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_02182	2.88e-96	-	-	-	-	-	-	-	-
CMHMHKIO_02183	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CMHMHKIO_02184	4.84e-278	-	-	-	V	-	-	-	Beta-lactamase
CMHMHKIO_02185	2.51e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CMHMHKIO_02186	3.31e-282	-	-	-	V	-	-	-	Beta-lactamase
CMHMHKIO_02187	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMHMHKIO_02188	1.62e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
CMHMHKIO_02189	7.45e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMHMHKIO_02190	1.13e-177	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMHMHKIO_02191	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
CMHMHKIO_02194	2.17e-205	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CMHMHKIO_02195	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
CMHMHKIO_02196	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_02197	1.71e-87	-	-	-	-	-	-	-	-
CMHMHKIO_02198	6.13e-100	-	-	-	S	-	-	-	function, without similarity to other proteins
CMHMHKIO_02199	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
CMHMHKIO_02200	4.07e-296	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
CMHMHKIO_02201	8.15e-77	-	-	-	-	-	-	-	-
CMHMHKIO_02202	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
CMHMHKIO_02203	6.28e-25	-	-	-	S	-	-	-	Virus attachment protein p12 family
CMHMHKIO_02204	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
CMHMHKIO_02205	8.65e-56	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
CMHMHKIO_02206	2.02e-168	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
CMHMHKIO_02209	3.72e-152	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
CMHMHKIO_02210	8.14e-79	-	-	-	S	-	-	-	MucBP domain
CMHMHKIO_02211	9.73e-109	-	-	-	-	-	-	-	-
CMHMHKIO_02214	5.93e-12	-	-	-	-	-	-	-	-
CMHMHKIO_02215	3.83e-61	-	-	-	L	-	-	-	BRCA1 C Terminus (BRCT) domain
CMHMHKIO_02216	1.14e-148	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
CMHMHKIO_02218	3.06e-133	is18	-	-	L	-	-	-	Integrase core domain
CMHMHKIO_02219	8.39e-21	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
CMHMHKIO_02220	2.19e-57	-	-	-	M	-	-	-	Cna protein B-type domain
CMHMHKIO_02221	6.2e-28	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
CMHMHKIO_02222	2.36e-288	-	-	-	S	-	-	-	Phage capsid family
CMHMHKIO_02224	9.08e-71	-	-	-	-	-	-	-	-
CMHMHKIO_02225	3.92e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
CMHMHKIO_02226	1.28e-75	-	-	-	-	-	-	-	-
CMHMHKIO_02227	9.07e-89	-	-	-	-	-	-	-	-
CMHMHKIO_02228	5.7e-153	-	-	-	-	-	-	-	-
CMHMHKIO_02229	1.73e-81	-	-	-	-	-	-	-	-
CMHMHKIO_02230	3.03e-192	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
CMHMHKIO_02231	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMHMHKIO_02232	6.2e-175	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CMHMHKIO_02233	5.34e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
CMHMHKIO_02234	4.77e-89	-	-	-	-	-	-	-	-
CMHMHKIO_02236	3.3e-144	-	-	-	-	-	-	-	-
CMHMHKIO_02237	6.42e-112	-	-	-	-	-	-	-	-
CMHMHKIO_02238	2.49e-182	-	-	-	K	-	-	-	M protein trans-acting positive regulator
CMHMHKIO_02239	5.16e-210	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMHMHKIO_02240	2.73e-140	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CMHMHKIO_02241	2.99e-309	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
CMHMHKIO_02242	1.65e-241	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMHMHKIO_02243	4.21e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CMHMHKIO_02244	5.89e-183	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CMHMHKIO_02245	0.000324	-	-	-	S	-	-	-	CsbD-like
CMHMHKIO_02247	4.05e-206	-	-	-	-	-	-	-	-
CMHMHKIO_02248	3.44e-64	-	-	-	-	-	-	-	-
CMHMHKIO_02249	8.29e-74	-	-	-	-	-	-	-	-
CMHMHKIO_02250	2.11e-69	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
CMHMHKIO_02253	2.44e-210	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
CMHMHKIO_02254	2.6e-188	-	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
CMHMHKIO_02255	5.33e-98	-	2.7.1.191, 2.7.1.203	-	G	ko:K02793,ko:K17464	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_02256	5.98e-111	-	2.7.1.203	-	G	ko:K17465	ko00030,ko01120,ko02060,map00030,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_02257	5.6e-170	-	-	-	G	ko:K17466	ko00030,ko01120,ko02060,map00030,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_02258	2.58e-196	-	-	-	G	ko:K02796,ko:K17467	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
CMHMHKIO_02259	1.83e-279	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
CMHMHKIO_02260	1.05e-146	dhaL	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	S	ko:K00863,ko:K05879	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak2
CMHMHKIO_02261	1.77e-237	-	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
CMHMHKIO_02262	5.39e-152	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
CMHMHKIO_02263	5.82e-130	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	sugar phosphate isomerase involved in capsule formation
CMHMHKIO_02264	5.41e-171	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
CMHMHKIO_02265	7.05e-312	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
CMHMHKIO_02266	6.55e-224	-	-	-	K	-	-	-	sugar-binding domain protein
CMHMHKIO_02267	5.02e-186	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
CMHMHKIO_02268	1.24e-89	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_02269	4.08e-112	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_02270	3.93e-184	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_02271	4.49e-197	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
CMHMHKIO_02272	2.01e-212	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
CMHMHKIO_02273	0.0	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	transporter
CMHMHKIO_02274	1.16e-303	-	-	-	C	-	-	-	FAD dependent oxidoreductase
CMHMHKIO_02275	2.07e-204	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
CMHMHKIO_02276	1.12e-205	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
CMHMHKIO_02277	1.05e-127	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
CMHMHKIO_02278	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_02279	3.99e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
CMHMHKIO_02280	2.39e-28	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CMHMHKIO_02281	4.98e-68	-	-	-	-	-	-	-	-
CMHMHKIO_02283	0.0	-	-	-	K	-	-	-	Sigma-54 interaction domain
CMHMHKIO_02284	1.17e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_02285	2.66e-117	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_02286	6.62e-197	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_02287	7.5e-200	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_02288	4.22e-70	-	-	-	-	-	-	-	-
CMHMHKIO_02290	2.94e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
CMHMHKIO_02291	8.29e-174	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
CMHMHKIO_02292	5.04e-147	-	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
CMHMHKIO_02293	2.35e-125	-	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
CMHMHKIO_02294	0.0	-	2.7.1.197	-	G	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_02295	5.75e-286	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
CMHMHKIO_02296	1.27e-248	-	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
CMHMHKIO_02297	2.48e-173	yxeO	-	-	E	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMHMHKIO_02298	5.72e-205	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
CMHMHKIO_02299	6.06e-147	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_02300	1.32e-153	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_02301	1.12e-304	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
CMHMHKIO_02303	1.33e-17	-	-	-	S	-	-	-	YvrJ protein family
CMHMHKIO_02304	2e-185	-	-	-	M	-	-	-	hydrolase, family 25
CMHMHKIO_02305	2.9e-171	ypiA	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMHMHKIO_02306	1.25e-148	-	-	-	C	-	-	-	Flavodoxin
CMHMHKIO_02307	6.23e-113	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_02308	5.69e-238	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CMHMHKIO_02309	6.07e-155	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_02310	3.74e-53	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMHMHKIO_02311	9.99e-86	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
CMHMHKIO_02312	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
CMHMHKIO_02313	2.62e-194	-	-	-	S	-	-	-	hydrolase
CMHMHKIO_02314	6.3e-60	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
CMHMHKIO_02315	1.15e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
CMHMHKIO_02316	1.48e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMHMHKIO_02317	2.18e-177	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMHMHKIO_02318	7.9e-196	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMHMHKIO_02319	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
CMHMHKIO_02320	1.51e-90	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_02321	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CMHMHKIO_02322	1.18e-157	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CMHMHKIO_02323	1.94e-248	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CMHMHKIO_02324	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
CMHMHKIO_02326	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
CMHMHKIO_02327	1.91e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CMHMHKIO_02328	5.84e-253	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
CMHMHKIO_02329	4.99e-105	-	-	-	-	-	-	-	-
CMHMHKIO_02330	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
CMHMHKIO_02331	7.24e-23	-	-	-	-	-	-	-	-
CMHMHKIO_02332	2.11e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_02333	2.1e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
CMHMHKIO_02334	4.95e-134	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
CMHMHKIO_02335	1.03e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
CMHMHKIO_02336	1.05e-101	-	-	-	O	-	-	-	OsmC-like protein
CMHMHKIO_02337	0.0	-	-	-	L	-	-	-	Exonuclease
CMHMHKIO_02338	5.14e-65	yczG	-	-	K	-	-	-	Helix-turn-helix domain
CMHMHKIO_02339	4.02e-262	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
CMHMHKIO_02340	2.07e-140	ydfF	-	-	K	-	-	-	Transcriptional
CMHMHKIO_02341	6.8e-140	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
CMHMHKIO_02342	2.65e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
CMHMHKIO_02343	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CMHMHKIO_02345	1.22e-249	pbpE	-	-	V	-	-	-	Beta-lactamase
CMHMHKIO_02346	1.35e-186	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
CMHMHKIO_02347	1.15e-183	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
CMHMHKIO_02348	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
CMHMHKIO_02349	6.16e-285	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
CMHMHKIO_02350	0.0	-	-	-	E	-	-	-	Amino acid permease
CMHMHKIO_02351	1.68e-98	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMHMHKIO_02352	9.58e-211	-	-	-	S	-	-	-	reductase
CMHMHKIO_02353	1.5e-256	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
CMHMHKIO_02354	4.55e-76	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CMHMHKIO_02355	1.68e-124	-	-	-	-	-	-	-	-
CMHMHKIO_02356	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMHMHKIO_02357	1.54e-75	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
CMHMHKIO_02358	3.96e-293	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMHMHKIO_02359	4.8e-66	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_02360	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
CMHMHKIO_02361	7.9e-136	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
CMHMHKIO_02362	0.0	yvcC	-	-	M	-	-	-	Cna protein B-type domain
CMHMHKIO_02363	8.54e-213	yvcC	-	-	M	-	-	-	Cna protein B-type domain
CMHMHKIO_02364	8.63e-164	-	-	-	M	-	-	-	domain protein
CMHMHKIO_02365	1.25e-236	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
CMHMHKIO_02366	3.16e-258	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CMHMHKIO_02367	1.05e-167	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMHMHKIO_02368	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CMHMHKIO_02369	9.4e-165	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
CMHMHKIO_02370	3.6e-253	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
CMHMHKIO_02372	9.72e-182	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
CMHMHKIO_02373	2.77e-271	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
CMHMHKIO_02374	2.15e-122	-	-	-	-	-	-	-	-
CMHMHKIO_02375	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
CMHMHKIO_02376	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
CMHMHKIO_02377	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
CMHMHKIO_02378	0.0	ycaM	-	-	E	-	-	-	amino acid
CMHMHKIO_02379	5.77e-118	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
CMHMHKIO_02380	8.19e-212	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
CMHMHKIO_02381	8.24e-143	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
CMHMHKIO_02382	2.09e-115	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
CMHMHKIO_02383	2.15e-44	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
CMHMHKIO_02384	1.53e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMHMHKIO_02385	2.21e-275	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMHMHKIO_02386	3.63e-216	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMHMHKIO_02387	1.65e-207	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
CMHMHKIO_02388	2.2e-222	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CMHMHKIO_02389	2.14e-24	-	-	-	-	-	-	-	-
CMHMHKIO_02391	5.52e-286	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMHMHKIO_02396	4.87e-173	-	-	-	-	-	-	-	-
CMHMHKIO_02397	2.33e-25	-	-	-	E	-	-	-	Zn peptidase
CMHMHKIO_02398	1.51e-80	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMHMHKIO_02401	4.03e-202	ps305	-	-	S	-	-	-	Protein of unknown function (Hypoth_ymh)
CMHMHKIO_02402	2.23e-179	-	-	-	S	-	-	-	ORF6N domain
CMHMHKIO_02404	1.66e-59	-	-	-	S	-	-	-	Domain of unknown function (DUF1883)
CMHMHKIO_02410	7.76e-181	-	-	-	L	-	-	-	Helix-turn-helix domain
CMHMHKIO_02411	5.09e-199	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
CMHMHKIO_02413	3.84e-94	-	-	-	-	-	-	-	-
CMHMHKIO_02414	6.1e-172	-	-	-	-	-	-	-	-
CMHMHKIO_02417	4.76e-105	-	-	-	-	-	-	-	-
CMHMHKIO_02419	2.96e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
CMHMHKIO_02420	4.5e-50	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Natural resistance-associated macrophage protein
CMHMHKIO_02421	4.68e-71	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMHMHKIO_02446	3.8e-39	-	-	-	-	-	-	-	-
CMHMHKIO_02447	6.37e-82	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
CMHMHKIO_02448	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
CMHMHKIO_02449	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
CMHMHKIO_02450	1.4e-58	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
CMHMHKIO_02451	1.5e-107	-	-	-	-	-	-	-	-
CMHMHKIO_02452	2.44e-143	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives, IS30 family
CMHMHKIO_02453	2.5e-174	-	-	-	L	-	-	-	Helix-turn-helix domain
CMHMHKIO_02454	2.46e-215	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CMHMHKIO_02455	0.0	-	-	-	L	-	-	-	Transposase DDE domain
CMHMHKIO_02456	1.07e-97	-	-	-	S	-	-	-	Phage portal protein
CMHMHKIO_02457	2.83e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CMHMHKIO_02458	4.24e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CMHMHKIO_02459	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
CMHMHKIO_02460	1.02e-219	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CMHMHKIO_02461	8.63e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
CMHMHKIO_02464	2.36e-111	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMHMHKIO_02465	2.68e-67	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_02466	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CMHMHKIO_02467	9.83e-37	-	-	-	-	-	-	-	-
CMHMHKIO_02468	1.98e-163	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
CMHMHKIO_02469	4.29e-226	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
CMHMHKIO_02470	4.19e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
CMHMHKIO_02471	4.53e-122	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
CMHMHKIO_02472	7.23e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
CMHMHKIO_02473	4.13e-181	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
CMHMHKIO_02474	3.73e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
CMHMHKIO_02475	3.37e-272	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CMHMHKIO_02476	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
CMHMHKIO_02477	6.8e-21	-	-	-	-	-	-	-	-
CMHMHKIO_02478	7.42e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CMHMHKIO_02480	4.59e-272	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
CMHMHKIO_02481	1.91e-192	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CMHMHKIO_02482	1.06e-156	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
CMHMHKIO_02484	1.83e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
CMHMHKIO_02485	1.92e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CMHMHKIO_02486	9.5e-199	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CMHMHKIO_02487	3.35e-252	-	-	-	-	-	-	-	-
CMHMHKIO_02489	1.39e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
CMHMHKIO_02490	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
CMHMHKIO_02491	6.45e-215	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
CMHMHKIO_02492	1.77e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_02493	6.83e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CMHMHKIO_02494	2.89e-181	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_02495	3.01e-225	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
CMHMHKIO_02496	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
CMHMHKIO_02497	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
CMHMHKIO_02498	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
CMHMHKIO_02499	1.53e-93	-	-	-	S	-	-	-	GtrA-like protein
CMHMHKIO_02500	3.91e-159	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
CMHMHKIO_02501	3.66e-310	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
CMHMHKIO_02502	9.85e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
CMHMHKIO_02503	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
CMHMHKIO_02504	1.12e-208	-	-	-	S	-	-	-	KR domain
CMHMHKIO_02505	1.71e-205	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
CMHMHKIO_02506	1.77e-158	ydgI	-	-	C	-	-	-	Nitroreductase family
CMHMHKIO_02507	3.19e-263	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
CMHMHKIO_02510	5.8e-248	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
CMHMHKIO_02511	1.17e-77	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
CMHMHKIO_02512	1.14e-63	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
CMHMHKIO_02513	4.91e-55	-	-	-	-	-	-	-	-
CMHMHKIO_02514	2.1e-247	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
CMHMHKIO_02515	2.78e-73	-	-	-	-	-	-	-	-
CMHMHKIO_02516	1.79e-104	-	-	-	-	-	-	-	-
CMHMHKIO_02517	5.77e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
CMHMHKIO_02518	6.44e-33	-	-	-	-	-	-	-	-
CMHMHKIO_02519	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMHMHKIO_02520	4.2e-65	-	-	-	-	-	-	-	-
CMHMHKIO_02521	5.96e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
CMHMHKIO_02522	8.76e-82	ywrF	-	-	S	-	-	-	Flavin reductase like domain
CMHMHKIO_02523	9.67e-91	-	-	-	-	-	-	-	-
CMHMHKIO_02524	6.56e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CMHMHKIO_02525	1.7e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
CMHMHKIO_02526	2.2e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
CMHMHKIO_02527	3.19e-206	mleR	-	-	K	-	-	-	LysR family
CMHMHKIO_02528	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
CMHMHKIO_02529	3.58e-217	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
CMHMHKIO_02530	8.23e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CMHMHKIO_02531	2.28e-113	-	-	-	C	-	-	-	FMN binding
CMHMHKIO_02532	1.32e-223	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
CMHMHKIO_02533	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
CMHMHKIO_02534	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
CMHMHKIO_02535	9.47e-79	-	-	-	-	-	-	-	-
CMHMHKIO_02536	3.81e-170	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMHMHKIO_02537	4.06e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
CMHMHKIO_02538	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
CMHMHKIO_02539	6.63e-232	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	carboxylic ester hydrolase activity
CMHMHKIO_02540	1.69e-58	-	-	-	-	-	-	-	-
CMHMHKIO_02541	4.89e-122	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMHMHKIO_02542	1.38e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CMHMHKIO_02543	9.07e-158	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
CMHMHKIO_02544	2.24e-101	-	-	-	K	-	-	-	Transcriptional regulator
CMHMHKIO_02545	2.4e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
CMHMHKIO_02546	3.28e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
CMHMHKIO_02547	4.36e-200	dkgB	-	-	S	-	-	-	reductase
CMHMHKIO_02548	4.98e-203	-	-	-	-	-	-	-	-
CMHMHKIO_02549	6.16e-199	-	-	-	S	-	-	-	Alpha beta hydrolase
CMHMHKIO_02550	1.29e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
CMHMHKIO_02551	4.49e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
CMHMHKIO_02552	4.17e-284	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
CMHMHKIO_02553	1.69e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CMHMHKIO_02554	1.3e-136	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
CMHMHKIO_02555	2.95e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CMHMHKIO_02556	1.59e-241	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CMHMHKIO_02557	1.11e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CMHMHKIO_02558	1.71e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CMHMHKIO_02559	4.49e-88	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CMHMHKIO_02560	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
CMHMHKIO_02561	2.06e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
CMHMHKIO_02562	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CMHMHKIO_02563	1.25e-264	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMHMHKIO_02564	1.13e-307	ytoI	-	-	K	-	-	-	DRTGG domain
CMHMHKIO_02565	3.03e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
CMHMHKIO_02566	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CMHMHKIO_02567	2.29e-225	-	-	-	-	-	-	-	-
CMHMHKIO_02568	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMHMHKIO_02570	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
CMHMHKIO_02571	2.67e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMHMHKIO_02572	1.3e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
CMHMHKIO_02573	2.84e-48	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CMHMHKIO_02574	1.89e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
CMHMHKIO_02575	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CMHMHKIO_02576	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CMHMHKIO_02577	1.04e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
CMHMHKIO_02578	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMHMHKIO_02579	9.86e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
CMHMHKIO_02580	6.97e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMHMHKIO_02581	2.04e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CMHMHKIO_02582	2.02e-112	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
CMHMHKIO_02583	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CMHMHKIO_02584	1.15e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
CMHMHKIO_02585	1.9e-175	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
CMHMHKIO_02586	6.56e-112	ykuL	-	-	S	-	-	-	CBS domain
CMHMHKIO_02587	3.55e-203	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
CMHMHKIO_02588	6.86e-198	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
CMHMHKIO_02589	1.49e-46	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CMHMHKIO_02590	1.69e-114	ytxH	-	-	S	-	-	-	YtxH-like protein
CMHMHKIO_02591	7.49e-117	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
CMHMHKIO_02592	3.25e-276	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CMHMHKIO_02593	3.03e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
CMHMHKIO_02594	3.35e-247	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
CMHMHKIO_02595	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
CMHMHKIO_02596	1.78e-240	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
CMHMHKIO_02597	1.06e-163	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
CMHMHKIO_02598	5.87e-177	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CMHMHKIO_02599	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
CMHMHKIO_02600	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
CMHMHKIO_02601	5.84e-51	-	-	-	-	-	-	-	-
CMHMHKIO_02602	1.46e-241	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
CMHMHKIO_02603	5.42e-150	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
CMHMHKIO_02604	2.58e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CMHMHKIO_02605	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CMHMHKIO_02606	6.42e-154	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
CMHMHKIO_02607	1.34e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CMHMHKIO_02608	6.43e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
CMHMHKIO_02609	1.83e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
CMHMHKIO_02610	2.26e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
CMHMHKIO_02611	2.84e-239	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
CMHMHKIO_02612	4.42e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMHMHKIO_02613	1.17e-82	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
CMHMHKIO_02614	3.42e-227	-	-	-	S	-	-	-	overlaps another CDS with the same product name
CMHMHKIO_02615	1.2e-227	-	-	-	S	-	-	-	overlaps another CDS with the same product name
CMHMHKIO_02618	1.55e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CMHMHKIO_02619	4.82e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMHMHKIO_02620	5.14e-195	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
CMHMHKIO_02622	2.5e-67	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
CMHMHKIO_02624	7.09e-113	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
CMHMHKIO_02625	5.77e-93	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMHMHKIO_02626	2.31e-110	-	-	-	C	-	-	-	Flavodoxin
CMHMHKIO_02627	1.33e-253	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
CMHMHKIO_02628	2.75e-148	-	-	-	GM	-	-	-	NmrA-like family
CMHMHKIO_02630	5.62e-132	-	-	-	Q	-	-	-	methyltransferase
CMHMHKIO_02631	7.76e-143	-	-	-	T	-	-	-	Sh3 type 3 domain protein
CMHMHKIO_02632	8.17e-153	-	-	-	F	-	-	-	glutamine amidotransferase
CMHMHKIO_02633	2.59e-174	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
CMHMHKIO_02634	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
CMHMHKIO_02635	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CMHMHKIO_02636	8.38e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
CMHMHKIO_02637	2.04e-129	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
CMHMHKIO_02638	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMHMHKIO_02639	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMHMHKIO_02640	0.0	ydaO	-	-	E	-	-	-	amino acid
CMHMHKIO_02641	1.31e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
CMHMHKIO_02642	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CMHMHKIO_02643	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMHMHKIO_02644	2.13e-143	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMHMHKIO_02645	1.01e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CMHMHKIO_02646	1.2e-238	-	-	-	-	-	-	-	-
CMHMHKIO_02647	5.93e-204	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_02648	4.97e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
CMHMHKIO_02649	1.1e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CMHMHKIO_02650	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
CMHMHKIO_02651	3.12e-68	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMHMHKIO_02652	5.99e-243	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMHMHKIO_02653	8.44e-130	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
CMHMHKIO_02654	3.82e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
CMHMHKIO_02655	8.43e-96	-	-	-	-	-	-	-	-
CMHMHKIO_02656	2.42e-117	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
CMHMHKIO_02657	7.46e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
CMHMHKIO_02658	3.86e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
CMHMHKIO_02659	1.49e-192	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMHMHKIO_02660	7.92e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
CMHMHKIO_02661	2.28e-223	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CMHMHKIO_02662	1.14e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
CMHMHKIO_02663	7.2e-151	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMHMHKIO_02664	2.95e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
CMHMHKIO_02665	1.26e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMHMHKIO_02666	7e-49	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CMHMHKIO_02667	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMHMHKIO_02668	4.38e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CMHMHKIO_02669	9.05e-67	-	-	-	-	-	-	-	-
CMHMHKIO_02670	8.53e-142	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
CMHMHKIO_02671	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMHMHKIO_02672	3.3e-59	-	-	-	-	-	-	-	-
CMHMHKIO_02673	1.49e-225	ccpB	-	-	K	-	-	-	lacI family
CMHMHKIO_02674	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
CMHMHKIO_02675	7.22e-207	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMHMHKIO_02676	1.37e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CMHMHKIO_02677	7.23e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMHMHKIO_02678	8.17e-285	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
CMHMHKIO_02679	3.64e-201	-	-	-	K	-	-	-	acetyltransferase
CMHMHKIO_02680	3.45e-87	-	-	-	-	-	-	-	-
CMHMHKIO_02681	4.33e-280	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
CMHMHKIO_02682	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CMHMHKIO_02683	1.89e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CMHMHKIO_02684	6.87e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMHMHKIO_02685	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
CMHMHKIO_02686	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
CMHMHKIO_02687	4.39e-89	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
CMHMHKIO_02688	7.84e-123	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
CMHMHKIO_02689	9.98e-128	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
CMHMHKIO_02690	4.31e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
CMHMHKIO_02691	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
CMHMHKIO_02692	3.77e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
CMHMHKIO_02693	1.71e-205	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMHMHKIO_02694	2.29e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
CMHMHKIO_02695	2.09e-30	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CMHMHKIO_02696	4.4e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CMHMHKIO_02697	1.13e-220	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
CMHMHKIO_02698	2.44e-216	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
CMHMHKIO_02699	2.2e-252	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMHMHKIO_02700	4.15e-188	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
CMHMHKIO_02701	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CMHMHKIO_02702	4.76e-105	-	-	-	S	-	-	-	NusG domain II
CMHMHKIO_02703	1.03e-127	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
CMHMHKIO_02704	3.28e-232	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CMHMHKIO_02706	2.3e-158	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
CMHMHKIO_02707	3.12e-250	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
CMHMHKIO_02709	5.04e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
CMHMHKIO_02710	9.39e-183	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMHMHKIO_02711	2.39e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CMHMHKIO_02712	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CMHMHKIO_02713	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
CMHMHKIO_02714	2.65e-139	-	-	-	-	-	-	-	-
CMHMHKIO_02716	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMHMHKIO_02717	3.45e-239	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
CMHMHKIO_02718	3.15e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
CMHMHKIO_02719	1.73e-182	-	-	-	K	-	-	-	SIS domain
CMHMHKIO_02720	8.77e-147	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
CMHMHKIO_02721	2.27e-225	-	-	-	S	-	-	-	Membrane
CMHMHKIO_02722	9.18e-83	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
CMHMHKIO_02723	3.39e-227	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMHMHKIO_02724	6.11e-186	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_02725	1.72e-169	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
CMHMHKIO_02726	5.59e-174	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
CMHMHKIO_02727	4.76e-288	inlJ	-	-	M	-	-	-	MucBP domain
CMHMHKIO_02728	5.79e-172	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMHMHKIO_02729	6.18e-206	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_02730	2.54e-211	-	-	-	K	-	-	-	sequence-specific DNA binding
CMHMHKIO_02731	5.49e-261	yacL	-	-	S	-	-	-	domain protein
CMHMHKIO_02732	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMHMHKIO_02733	4.85e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
CMHMHKIO_02734	1.22e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
CMHMHKIO_02735	5.93e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
CMHMHKIO_02736	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
CMHMHKIO_02737	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CMHMHKIO_02738	1.97e-256	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
CMHMHKIO_02739	3.84e-279	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMHMHKIO_02740	5.79e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMHMHKIO_02741	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CMHMHKIO_02742	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
CMHMHKIO_02743	3.68e-136	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
CMHMHKIO_02744	1.19e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMHMHKIO_02745	4.71e-263	-	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
CMHMHKIO_02746	5.25e-61	-	-	-	-	-	-	-	-
CMHMHKIO_02747	2.08e-265	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
CMHMHKIO_02748	1.59e-28	yhjA	-	-	K	-	-	-	CsbD-like
CMHMHKIO_02749	2.28e-293	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CMHMHKIO_02750	3.02e-275	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
CMHMHKIO_02751	1.45e-180	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
CMHMHKIO_02752	6.53e-272	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
CMHMHKIO_02753	9.8e-247	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
CMHMHKIO_02755	1.5e-44	-	-	-	-	-	-	-	-
CMHMHKIO_02756	6.09e-53	-	-	-	-	-	-	-	-
CMHMHKIO_02757	4.23e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
CMHMHKIO_02758	5.68e-280	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CMHMHKIO_02759	4.65e-192	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CMHMHKIO_02761	2.57e-55	-	-	-	-	-	-	-	-
CMHMHKIO_02762	1.38e-295	-	-	-	S	-	-	-	Membrane
CMHMHKIO_02763	2.81e-192	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
CMHMHKIO_02764	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
CMHMHKIO_02765	5.21e-310	-	-	-	-	-	-	-	-
CMHMHKIO_02766	0.0	-	-	-	M	-	-	-	domain protein
CMHMHKIO_02767	2.09e-89	-	-	-	S	-	-	-	Phage portal protein
CMHMHKIO_02768	8.87e-99	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CMHMHKIO_02769	5.04e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CMHMHKIO_02770	2.82e-181	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
CMHMHKIO_02771	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CMHMHKIO_02772	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CMHMHKIO_02773	2.3e-228	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CMHMHKIO_02774	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
CMHMHKIO_02775	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
CMHMHKIO_02776	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
CMHMHKIO_02777	1.8e-157	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CMHMHKIO_02778	2.35e-270	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMHMHKIO_02779	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
CMHMHKIO_02780	1.96e-292	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMHMHKIO_02781	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_02782	4.66e-196	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_02783	1.34e-22	-	-	-	-	-	-	-	-
CMHMHKIO_02784	2.46e-36	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
CMHMHKIO_02785	2.99e-310	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
CMHMHKIO_02786	4.3e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMHMHKIO_02787	3.82e-189	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMHMHKIO_02788	1.42e-212	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
CMHMHKIO_02789	3.08e-248	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMHMHKIO_02790	3.63e-136	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
CMHMHKIO_02791	7.57e-119	-	-	-	-	-	-	-	-
CMHMHKIO_02792	4e-203	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMHMHKIO_02793	1.45e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMHMHKIO_02794	5.22e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
CMHMHKIO_02795	1.35e-107	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
CMHMHKIO_02797	1.6e-214	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMHMHKIO_02798	2.2e-276	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMHMHKIO_02799	1.97e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CMHMHKIO_02800	8.14e-194	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
CMHMHKIO_02801	4.74e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
CMHMHKIO_02802	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CMHMHKIO_02803	1.97e-124	-	-	-	K	-	-	-	Cupin domain
CMHMHKIO_02804	9.1e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CMHMHKIO_02805	2.49e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_02806	7.08e-188	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMHMHKIO_02807	8.49e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMHMHKIO_02809	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
CMHMHKIO_02810	1.82e-144	-	-	-	K	-	-	-	Transcriptional regulator
CMHMHKIO_02811	1.69e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CMHMHKIO_02812	1.09e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CMHMHKIO_02813	3.82e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CMHMHKIO_02814	1.36e-217	ybbR	-	-	S	-	-	-	YbbR-like protein
CMHMHKIO_02815	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMHMHKIO_02816	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CMHMHKIO_02818	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
CMHMHKIO_02819	3.35e-106	-	-	-	S	-	-	-	VanZ like family
CMHMHKIO_02820	5.85e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
CMHMHKIO_02821	1.02e-196	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
CMHMHKIO_02822	7.91e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
CMHMHKIO_02823	1e-35	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
CMHMHKIO_02825	8.98e-30	-	-	-	-	-	-	-	-
CMHMHKIO_02826	2.01e-24	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
CMHMHKIO_02828	3.73e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
CMHMHKIO_02829	2.1e-81	-	-	-	-	-	-	-	-
CMHMHKIO_02830	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CMHMHKIO_02831	7.51e-191	arbV	-	-	I	-	-	-	Phosphate acyltransferases
CMHMHKIO_02832	2.02e-212	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
CMHMHKIO_02833	2.41e-235	arbY	-	-	M	-	-	-	family 8
CMHMHKIO_02834	9.24e-214	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
CMHMHKIO_02835	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
CMHMHKIO_02838	6.55e-93	-	-	-	S	-	-	-	SdpI/YhfL protein family
CMHMHKIO_02839	3.55e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
CMHMHKIO_02840	0.0	yclK	-	-	T	-	-	-	Histidine kinase
CMHMHKIO_02841	5.76e-22	-	-	-	S	-	-	-	acetyltransferase
CMHMHKIO_02842	2.45e-75	-	-	-	S	-	-	-	acetyltransferase
CMHMHKIO_02843	1.16e-19	-	-	-	-	-	-	-	-
CMHMHKIO_02844	1.27e-94	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
CMHMHKIO_02845	1.53e-88	-	-	-	-	-	-	-	-
CMHMHKIO_02846	8.56e-74	-	-	-	-	-	-	-	-
CMHMHKIO_02847	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
CMHMHKIO_02849	3.92e-270	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
CMHMHKIO_02850	1.28e-182	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
CMHMHKIO_02851	5.65e-46	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
CMHMHKIO_02852	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
CMHMHKIO_02853	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMHMHKIO_02854	3e-271	camS	-	-	S	-	-	-	sex pheromone
CMHMHKIO_02855	3.61e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMHMHKIO_02856	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CMHMHKIO_02857	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMHMHKIO_02858	4.97e-248	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
CMHMHKIO_02859	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMHMHKIO_02860	7.92e-282	yttB	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_02861	6.2e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMHMHKIO_02862	8.52e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
CMHMHKIO_02863	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
CMHMHKIO_02864	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_02865	4.37e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
CMHMHKIO_02866	2.87e-213	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
CMHMHKIO_02867	3.38e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
CMHMHKIO_02868	4.3e-40	-	-	-	-	-	-	-	-
CMHMHKIO_02869	6.15e-181	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
CMHMHKIO_02870	9.39e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
CMHMHKIO_02871	1.9e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
CMHMHKIO_02872	2.69e-227	mocA	-	-	S	-	-	-	Oxidoreductase
CMHMHKIO_02873	1.79e-304	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
CMHMHKIO_02874	2.76e-74	chbA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
CMHMHKIO_02875	4.49e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
CMHMHKIO_02877	6.45e-06	-	-	-	-	-	-	-	-
CMHMHKIO_02878	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CMHMHKIO_02879	3.61e-309	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
CMHMHKIO_02880	2.96e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_02881	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
CMHMHKIO_02882	9.73e-230	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
CMHMHKIO_02883	1.24e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
CMHMHKIO_02884	4.05e-205	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
CMHMHKIO_02885	3.86e-261	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CMHMHKIO_02887	5.92e-20	-	-	-	-	-	-	-	-
CMHMHKIO_02888	1.09e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
CMHMHKIO_02889	4.58e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CMHMHKIO_02890	4.04e-76	-	-	-	-	-	-	-	-
CMHMHKIO_02891	5.96e-28	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
CMHMHKIO_02894	1.01e-225	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMHMHKIO_02895	6.64e-39	-	-	-	-	-	-	-	-
CMHMHKIO_02896	1.8e-135	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMHMHKIO_02897	0.0	-	-	-	-	-	-	-	-
CMHMHKIO_02899	3.46e-168	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMHMHKIO_02900	5.01e-172	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMHMHKIO_02901	2.17e-245	ynjC	-	-	S	-	-	-	Cell surface protein
CMHMHKIO_02903	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
CMHMHKIO_02904	1.45e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
CMHMHKIO_02905	1.1e-76	-	-	-	-	-	-	-	-
CMHMHKIO_02906	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CMHMHKIO_02907	6.45e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMHMHKIO_02908	2.01e-205	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
CMHMHKIO_02909	8.09e-180	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
CMHMHKIO_02910	8.86e-62	-	-	-	S	-	-	-	Thiamine-binding protein
CMHMHKIO_02911	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
CMHMHKIO_02912	4.77e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMHMHKIO_02913	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
CMHMHKIO_02915	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
CMHMHKIO_02916	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMHMHKIO_02917	1.15e-25	-	-	-	-	-	-	-	-
CMHMHKIO_02919	8.72e-105	-	-	-	S	-	-	-	NUDIX domain
CMHMHKIO_02920	1.33e-276	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
CMHMHKIO_02921	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
CMHMHKIO_02922	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
CMHMHKIO_02923	6.18e-150	-	-	-	-	-	-	-	-
CMHMHKIO_02924	2.18e-289	-	-	-	S	ko:K06872	-	ko00000	TPM domain
CMHMHKIO_02925	8.76e-178	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
CMHMHKIO_02926	6.45e-74	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
CMHMHKIO_02927	1.47e-07	-	-	-	-	-	-	-	-
CMHMHKIO_02928	5.12e-117	-	-	-	-	-	-	-	-
CMHMHKIO_02929	4.85e-65	-	-	-	-	-	-	-	-
CMHMHKIO_02930	1.63e-109	-	-	-	C	-	-	-	Flavodoxin
CMHMHKIO_02931	5.54e-50	-	-	-	-	-	-	-	-
CMHMHKIO_02932	2.82e-36	-	-	-	-	-	-	-	-
CMHMHKIO_02933	2.86e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMHMHKIO_02934	2.27e-94	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
CMHMHKIO_02935	1.93e-52	-	-	-	S	-	-	-	Transglycosylase associated protein
CMHMHKIO_02936	5.77e-113	-	-	-	S	-	-	-	Protein conserved in bacteria
CMHMHKIO_02937	4.15e-34	-	-	-	-	-	-	-	-
CMHMHKIO_02938	8.12e-90	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CMHMHKIO_02939	1.97e-92	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CMHMHKIO_02940	9.28e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
CMHMHKIO_02941	1.42e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
CMHMHKIO_02942	1.2e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CMHMHKIO_02943	3.05e-139	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
CMHMHKIO_02944	6.67e-165	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
CMHMHKIO_02945	4.01e-87	-	-	-	-	-	-	-	-
CMHMHKIO_02946	3.36e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
CMHMHKIO_02947	6.84e-189	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CMHMHKIO_02948	1.49e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
CMHMHKIO_02949	1.11e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CMHMHKIO_02950	3.26e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
CMHMHKIO_02951	9.76e-237	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CMHMHKIO_02952	7.77e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
CMHMHKIO_02953	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMHMHKIO_02954	1.23e-157	-	-	-	-	-	-	-	-
CMHMHKIO_02955	1.68e-156	vanR	-	-	K	-	-	-	response regulator
CMHMHKIO_02956	2.81e-278	hpk31	-	-	T	-	-	-	Histidine kinase
CMHMHKIO_02957	4.75e-304	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CMHMHKIO_02958	1.02e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMHMHKIO_02959	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMHMHKIO_02960	2.71e-182	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
CMHMHKIO_02961	3.48e-212	yvgN	-	-	C	-	-	-	Aldo keto reductase
CMHMHKIO_02962	3.54e-187	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
CMHMHKIO_02963	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CMHMHKIO_02964	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CMHMHKIO_02965	8.47e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CMHMHKIO_02966	6.58e-228	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CMHMHKIO_02967	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CMHMHKIO_02968	9.62e-247	-	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
CMHMHKIO_02969	3.37e-249	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
CMHMHKIO_02970	1.27e-223	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CMHMHKIO_02971	1.4e-204	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
CMHMHKIO_02972	8.67e-88	yodA	-	-	S	-	-	-	Tautomerase enzyme
CMHMHKIO_02973	3.12e-187	gntR	-	-	K	-	-	-	rpiR family
CMHMHKIO_02974	1.27e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
CMHMHKIO_02975	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
CMHMHKIO_02976	6.55e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
CMHMHKIO_02977	3.01e-315	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
CMHMHKIO_02978	6.41e-196	-	-	-	S	-	-	-	Glycosyl transferase family 2
CMHMHKIO_02979	7.56e-165	welB	-	-	S	-	-	-	Glycosyltransferase like family 2
CMHMHKIO_02980	4.2e-208	-	-	-	S	-	-	-	Glycosyltransferase like family 2
CMHMHKIO_02981	1.99e-192	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
CMHMHKIO_02982	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CMHMHKIO_02983	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
CMHMHKIO_02984	1.85e-207	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
CMHMHKIO_02985	6.33e-254	-	-	-	S	-	-	-	Protein conserved in bacteria
CMHMHKIO_02986	3.74e-75	-	-	-	-	-	-	-	-
CMHMHKIO_02987	1.01e-167	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMHMHKIO_02988	5.98e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
CMHMHKIO_02989	3.1e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
CMHMHKIO_02990	2.25e-207	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
CMHMHKIO_02991	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
CMHMHKIO_02992	4.84e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CMHMHKIO_02993	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CMHMHKIO_02994	2.43e-103	-	-	-	T	-	-	-	Sh3 type 3 domain protein
CMHMHKIO_02995	7.68e-174	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
CMHMHKIO_02996	2.32e-188	-	-	-	M	-	-	-	Glycosyltransferase like family 2
CMHMHKIO_02997	1.32e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
CMHMHKIO_02998	2.19e-54	-	-	-	-	-	-	-	-
CMHMHKIO_02999	1.26e-139	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CMHMHKIO_03000	6.35e-228	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
CMHMHKIO_03001	0.0	-	-	-	S	-	-	-	ABC transporter
CMHMHKIO_03002	3.54e-176	ypaC	-	-	Q	-	-	-	Methyltransferase domain