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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PAILFIKI_00003	2.54e-77	ykvN	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00004	2.47e-168	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
PAILFIKI_00005	1.24e-50	yoqH	-	-	M	-	-	-	LysM domain
PAILFIKI_00011	2.13e-124	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
PAILFIKI_00012	7.44e-312	yoeA	-	-	V	-	-	-	MATE efflux family protein
PAILFIKI_00013	1.16e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PAILFIKI_00014	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
PAILFIKI_00015	2.61e-299	ybbC	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_00016	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
PAILFIKI_00017	2.56e-308	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
PAILFIKI_00018	5.86e-310	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_00019	3.84e-207	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PAILFIKI_00020	7.13e-110	ybbJ	-	-	J	-	-	-	acetyltransferase
PAILFIKI_00021	1.93e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
PAILFIKI_00023	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_00024	3.31e-281	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
PAILFIKI_00025	1.22e-311	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAILFIKI_00026	7.74e-231	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
PAILFIKI_00027	3.13e-253	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
PAILFIKI_00028	2.62e-286	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
PAILFIKI_00029	1.08e-222	ybaS	-	-	S	-	-	-	Na -dependent transporter
PAILFIKI_00030	1.35e-143	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
PAILFIKI_00031	1.43e-229	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAILFIKI_00032	1.8e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAILFIKI_00033	1.21e-219	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
PAILFIKI_00034	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
PAILFIKI_00035	1.57e-190	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PAILFIKI_00036	1.04e-290	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PAILFIKI_00037	7.51e-287	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PAILFIKI_00038	9.47e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PAILFIKI_00039	2.61e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PAILFIKI_00040	2.05e-121	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PAILFIKI_00042	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
PAILFIKI_00043	3.91e-100	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
PAILFIKI_00044	4.04e-169	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
PAILFIKI_00045	7.27e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
PAILFIKI_00046	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PAILFIKI_00047	1.73e-228	ykvI	-	-	S	-	-	-	membrane
PAILFIKI_00048	6.57e-254	-	-	-	-	-	-	-	-
PAILFIKI_00049	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PAILFIKI_00050	6.25e-103	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
PAILFIKI_00051	1.76e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PAILFIKI_00052	2.44e-287	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PAILFIKI_00053	4.44e-251	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PAILFIKI_00055	1.31e-113	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PAILFIKI_00056	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_00057	3.74e-241	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
PAILFIKI_00058	3.07e-32	ykzE	-	-	-	-	-	-	-
PAILFIKI_00059	3e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
PAILFIKI_00060	1.62e-309	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
PAILFIKI_00061	6.35e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PAILFIKI_00062	1.62e-161	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
PAILFIKI_00063	5.7e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
PAILFIKI_00064	3.6e-250	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
PAILFIKI_00065	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAILFIKI_00066	2.91e-173	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PAILFIKI_00067	1.43e-131	ykoX	-	-	S	-	-	-	membrane-associated protein
PAILFIKI_00068	3.42e-202	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PAILFIKI_00069	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
PAILFIKI_00070	3.81e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
PAILFIKI_00071	5.46e-105	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
PAILFIKI_00072	5.25e-37	ykoL	-	-	-	-	-	-	-
PAILFIKI_00073	1.11e-23	-	-	-	-	-	-	-	-
PAILFIKI_00074	1.23e-69	tnrA	-	-	K	-	-	-	transcriptional
PAILFIKI_00075	3.52e-309	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
PAILFIKI_00077	1.27e-309	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
PAILFIKI_00078	4.66e-126	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PAILFIKI_00079	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_00080	2.18e-169	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PAILFIKI_00081	1.28e-189	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PAILFIKI_00082	2.58e-226	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PAILFIKI_00083	6.38e-183	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
PAILFIKI_00084	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
PAILFIKI_00085	1.95e-102	gerD	-	-	-	ko:K06294	-	ko00000	-
PAILFIKI_00086	9e-254	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PAILFIKI_00087	2.31e-172	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
PAILFIKI_00088	9.25e-103	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
PAILFIKI_00089	9.4e-110	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
PAILFIKI_00090	1.76e-185	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
PAILFIKI_00091	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PAILFIKI_00092	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PAILFIKI_00093	3.56e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PAILFIKI_00094	7.93e-178	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAILFIKI_00095	2.09e-191	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAILFIKI_00096	1.45e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAILFIKI_00097	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PAILFIKI_00098	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAILFIKI_00099	4.61e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PAILFIKI_00100	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PAILFIKI_00101	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PAILFIKI_00102	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PAILFIKI_00103	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
PAILFIKI_00104	4.34e-158	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PAILFIKI_00105	1.34e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PAILFIKI_00106	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
PAILFIKI_00107	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PAILFIKI_00108	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PAILFIKI_00109	8.29e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PAILFIKI_00110	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PAILFIKI_00111	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PAILFIKI_00112	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PAILFIKI_00113	5.43e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PAILFIKI_00114	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PAILFIKI_00115	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PAILFIKI_00116	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PAILFIKI_00117	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PAILFIKI_00118	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PAILFIKI_00119	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PAILFIKI_00120	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PAILFIKI_00121	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PAILFIKI_00122	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PAILFIKI_00123	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PAILFIKI_00124	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PAILFIKI_00125	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PAILFIKI_00126	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PAILFIKI_00127	2.33e-239	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
PAILFIKI_00128	2.35e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PAILFIKI_00129	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PAILFIKI_00130	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PAILFIKI_00131	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PAILFIKI_00132	5.94e-46	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
PAILFIKI_00133	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAILFIKI_00134	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAILFIKI_00135	1.2e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PAILFIKI_00136	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PAILFIKI_00137	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PAILFIKI_00138	8.66e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PAILFIKI_00139	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PAILFIKI_00140	1.28e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PAILFIKI_00141	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PAILFIKI_00142	1.39e-150	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
PAILFIKI_00143	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
PAILFIKI_00144	1.01e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAILFIKI_00145	4.11e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PAILFIKI_00146	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PAILFIKI_00147	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
PAILFIKI_00148	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PAILFIKI_00149	3.02e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PAILFIKI_00150	2.38e-158	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PAILFIKI_00151	8.6e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
PAILFIKI_00152	7.66e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PAILFIKI_00153	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PAILFIKI_00154	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
PAILFIKI_00155	1.63e-258	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PAILFIKI_00156	1.14e-83	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
PAILFIKI_00157	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
PAILFIKI_00158	8.24e-234	yaaC	-	-	S	-	-	-	YaaC-like Protein
PAILFIKI_00159	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PAILFIKI_00160	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PAILFIKI_00161	1.29e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PAILFIKI_00162	2.86e-139	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PAILFIKI_00163	1.3e-284	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PAILFIKI_00164	1.9e-257	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PAILFIKI_00165	7.51e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
PAILFIKI_00166	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
PAILFIKI_00167	5.59e-275	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
PAILFIKI_00168	1.44e-128	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
PAILFIKI_00169	2.48e-111	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PAILFIKI_00170	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAILFIKI_00171	9.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PAILFIKI_00172	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PAILFIKI_00173	5.4e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PAILFIKI_00174	6.44e-50	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
PAILFIKI_00177	6.67e-123	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
PAILFIKI_00178	1.08e-277	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
PAILFIKI_00179	5.61e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
PAILFIKI_00180	2.98e-104	yuaE	-	-	S	-	-	-	DinB superfamily
PAILFIKI_00181	6.79e-141	-	-	-	S	-	-	-	MOSC domain
PAILFIKI_00182	1.74e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
PAILFIKI_00183	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PAILFIKI_00184	7.09e-125	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
PAILFIKI_00185	9.28e-121	yuaB	-	-	-	-	-	-	-
PAILFIKI_00186	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
PAILFIKI_00187	2.58e-191	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PAILFIKI_00188	1.07e-280	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PAILFIKI_00189	3.73e-157	-	-	-	G	-	-	-	Cupin
PAILFIKI_00190	4.37e-68	yjcN	-	-	-	-	-	-	-
PAILFIKI_00192	6.56e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PAILFIKI_00193	9.96e-251	yubA	-	-	S	-	-	-	transporter activity
PAILFIKI_00194	1.29e-235	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
PAILFIKI_00195	6.95e-127	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PAILFIKI_00196	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
PAILFIKI_00197	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
PAILFIKI_00198	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
PAILFIKI_00199	1.32e-315	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
PAILFIKI_00200	2.22e-179	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
PAILFIKI_00201	6.59e-55	-	-	-	-	-	-	-	-
PAILFIKI_00202	2.01e-242	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PAILFIKI_00203	7.72e-98	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
PAILFIKI_00204	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
PAILFIKI_00205	1.63e-296	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
PAILFIKI_00206	1.67e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
PAILFIKI_00207	2.16e-23	-	-	-	-	-	-	-	-
PAILFIKI_00208	4.93e-35	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
PAILFIKI_00209	4.84e-231	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
PAILFIKI_00210	8.53e-95	yugN	-	-	S	-	-	-	YugN-like family
PAILFIKI_00212	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PAILFIKI_00213	1.32e-131	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
PAILFIKI_00214	4.34e-152	ycaC	-	-	Q	-	-	-	Isochorismatase family
PAILFIKI_00215	1.37e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
PAILFIKI_00216	2.24e-284	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
PAILFIKI_00217	3.14e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
PAILFIKI_00218	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
PAILFIKI_00219	1.68e-266	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
PAILFIKI_00220	3.75e-109	alaR	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00221	1.64e-199	yugF	-	-	I	-	-	-	Hydrolase
PAILFIKI_00222	4.25e-55	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
PAILFIKI_00223	1.92e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PAILFIKI_00224	2.88e-289	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_00225	2.81e-88	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
PAILFIKI_00226	3.22e-152	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
PAILFIKI_00227	3.4e-259	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
PAILFIKI_00228	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
PAILFIKI_00229	5.29e-95	yuxK	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_00230	9.25e-101	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
PAILFIKI_00231	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
PAILFIKI_00232	6.58e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
PAILFIKI_00233	4.98e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
PAILFIKI_00234	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_00235	2.72e-238	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PAILFIKI_00236	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PAILFIKI_00238	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PAILFIKI_00239	6.3e-90	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAILFIKI_00240	8.54e-67	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAILFIKI_00241	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAILFIKI_00242	3.43e-87	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAILFIKI_00243	5.47e-52	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAILFIKI_00244	1.21e-78	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
PAILFIKI_00245	4e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
PAILFIKI_00246	8.07e-148	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAILFIKI_00247	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_00249	1.24e-196	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Polyprenyl synthetase
PAILFIKI_00250	2.66e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
PAILFIKI_00252	4.23e-67	yuzC	-	-	-	-	-	-	-
PAILFIKI_00253	5.64e-295	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
PAILFIKI_00254	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PAILFIKI_00255	8.02e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
PAILFIKI_00256	7.94e-90	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PAILFIKI_00257	5.46e-51	yueH	-	-	S	-	-	-	YueH-like protein
PAILFIKI_00258	6.33e-46	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
PAILFIKI_00259	2.67e-238	yueF	-	-	S	-	-	-	transporter activity
PAILFIKI_00260	2.81e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
PAILFIKI_00261	1.57e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
PAILFIKI_00262	2.04e-169	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAILFIKI_00263	8.01e-102	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
PAILFIKI_00264	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
PAILFIKI_00265	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PAILFIKI_00266	6.52e-275	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
PAILFIKI_00267	5.28e-53	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
PAILFIKI_00268	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
PAILFIKI_00269	1.22e-290	yukF	-	-	QT	-	-	-	Transcriptional regulator
PAILFIKI_00270	5.7e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
PAILFIKI_00271	3.06e-171	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
PAILFIKI_00272	9.15e-45	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
PAILFIKI_00273	3.05e-226	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_00274	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_00275	7.94e-220	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
PAILFIKI_00276	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
PAILFIKI_00277	3.2e-285	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
PAILFIKI_00278	2.03e-170	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAILFIKI_00279	1.72e-209	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
PAILFIKI_00280	1.13e-155	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
PAILFIKI_00281	3.73e-131	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
PAILFIKI_00282	8.19e-276	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
PAILFIKI_00283	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PAILFIKI_00284	8.29e-100	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
PAILFIKI_00285	9.86e-153	yuiC	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_00286	2.45e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
PAILFIKI_00287	3.42e-300	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PAILFIKI_00288	4.19e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
PAILFIKI_00290	1.35e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PAILFIKI_00291	2.32e-39	-	-	-	-	-	-	-	-
PAILFIKI_00292	5.92e-93	-	-	-	CP	-	-	-	Membrane
PAILFIKI_00293	2.16e-71	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PAILFIKI_00294	6.03e-70	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PAILFIKI_00296	5.3e-44	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
PAILFIKI_00298	4.15e-122	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
PAILFIKI_00299	9.01e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAILFIKI_00300	3.25e-81	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
PAILFIKI_00301	2.25e-207	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PAILFIKI_00302	1.49e-273	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PAILFIKI_00303	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
PAILFIKI_00304	8.47e-266	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PAILFIKI_00305	1.34e-72	yuzD	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_00306	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
PAILFIKI_00307	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
PAILFIKI_00308	6.76e-217	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PAILFIKI_00309	5.41e-250	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PAILFIKI_00310	8.26e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PAILFIKI_00311	1.55e-250	yutH	-	-	S	-	-	-	Spore coat protein
PAILFIKI_00312	1.75e-108	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
PAILFIKI_00313	1.38e-178	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PAILFIKI_00314	1.55e-95	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
PAILFIKI_00315	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_00316	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PAILFIKI_00317	8.24e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
PAILFIKI_00318	2.75e-167	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
PAILFIKI_00319	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PAILFIKI_00320	3.01e-186	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PAILFIKI_00321	1.8e-217	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
PAILFIKI_00322	3.04e-80	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
PAILFIKI_00323	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
PAILFIKI_00324	8.78e-18	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
PAILFIKI_00326	2.77e-12	-	-	-	-	-	-	-	-
PAILFIKI_00327	3.55e-30	-	-	-	-	-	-	-	-
PAILFIKI_00328	4.28e-274	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_00329	2.32e-299	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PAILFIKI_00330	9.02e-295	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PAILFIKI_00331	4.09e-217	bsn	-	-	L	-	-	-	Ribonuclease
PAILFIKI_00332	4.53e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_00333	4.84e-172	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
PAILFIKI_00334	2.16e-205	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
PAILFIKI_00335	8.84e-210	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
PAILFIKI_00336	1.68e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PAILFIKI_00337	2.12e-312	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
PAILFIKI_00338	1.57e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PAILFIKI_00339	2.73e-211	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PAILFIKI_00341	4.36e-94	-	-	-	-	-	-	-	-
PAILFIKI_00342	1.75e-28	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
PAILFIKI_00344	5.74e-86	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
PAILFIKI_00345	2.72e-261	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
PAILFIKI_00346	1.16e-48	-	-	-	-	-	-	-	-
PAILFIKI_00348	6.17e-104	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
PAILFIKI_00349	2.94e-200	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PAILFIKI_00350	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
PAILFIKI_00351	5.15e-100	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
PAILFIKI_00352	2.31e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PAILFIKI_00353	1.23e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
PAILFIKI_00354	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PAILFIKI_00355	5.13e-84	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PAILFIKI_00356	9e-187	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
PAILFIKI_00357	1.91e-134	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
PAILFIKI_00358	3.71e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PAILFIKI_00359	1.29e-76	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
PAILFIKI_00360	1.64e-72	yusE	-	-	CO	-	-	-	Thioredoxin
PAILFIKI_00361	1.08e-82	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
PAILFIKI_00362	1.8e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
PAILFIKI_00363	4.16e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PAILFIKI_00364	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
PAILFIKI_00365	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
PAILFIKI_00366	1.56e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
PAILFIKI_00367	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
PAILFIKI_00368	8.5e-212	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
PAILFIKI_00369	3.2e-58	-	-	-	-	-	-	-	-
PAILFIKI_00370	5.21e-71	yusN	-	-	M	-	-	-	Coat F domain
PAILFIKI_00371	1.31e-89	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
PAILFIKI_00372	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
PAILFIKI_00373	1.24e-86	yusQ	-	-	S	-	-	-	Tautomerase enzyme
PAILFIKI_00374	1.81e-169	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAILFIKI_00375	4.52e-202	yusT	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
PAILFIKI_00376	2.31e-201	-	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00377	4.14e-176	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
PAILFIKI_00378	2.83e-239	apbA	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAILFIKI_00379	2.15e-52	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
PAILFIKI_00380	1.29e-192	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PAILFIKI_00381	7.61e-60	-	-	-	S	-	-	-	YusW-like protein
PAILFIKI_00382	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
PAILFIKI_00383	1.29e-195	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAILFIKI_00384	2.39e-102	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PAILFIKI_00385	1.26e-303	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAILFIKI_00386	3.7e-163	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_00387	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_00388	2.68e-32	-	-	-	-	-	-	-	-
PAILFIKI_00389	1.8e-200	yuxN	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00390	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PAILFIKI_00391	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
PAILFIKI_00392	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
PAILFIKI_00393	2.16e-244	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
PAILFIKI_00394	2.93e-260	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
PAILFIKI_00395	8.35e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAILFIKI_00396	3.48e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_00397	2.99e-162	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
PAILFIKI_00398	1.43e-192	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
PAILFIKI_00399	9.74e-134	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PAILFIKI_00400	3.14e-66	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
PAILFIKI_00401	2.77e-289	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_00402	1.54e-131	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
PAILFIKI_00403	3.18e-281	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PAILFIKI_00404	7.3e-227	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAILFIKI_00405	1.93e-214	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PAILFIKI_00406	8.63e-181	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAILFIKI_00407	3.79e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
PAILFIKI_00408	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
PAILFIKI_00409	7.74e-172	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_00410	1.67e-50	-	-	-	-	-	-	-	-
PAILFIKI_00411	3.23e-134	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
PAILFIKI_00412	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
PAILFIKI_00413	8.91e-295	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
PAILFIKI_00414	8.36e-89	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
PAILFIKI_00415	1.39e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PAILFIKI_00416	2.27e-224	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAILFIKI_00417	3.29e-238	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAILFIKI_00418	1.28e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PAILFIKI_00419	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
PAILFIKI_00420	1.29e-20	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
PAILFIKI_00421	4.11e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
PAILFIKI_00422	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
PAILFIKI_00423	3.88e-211	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
PAILFIKI_00424	1.95e-178	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
PAILFIKI_00425	2.33e-126	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
PAILFIKI_00426	4.32e-148	yfiK	-	-	K	-	-	-	Regulator
PAILFIKI_00427	7.24e-245	-	-	-	T	-	-	-	Histidine kinase
PAILFIKI_00428	1.66e-218	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
PAILFIKI_00429	1.22e-249	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PAILFIKI_00430	5.2e-255	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
PAILFIKI_00431	7.23e-200	yvgN	-	-	S	-	-	-	reductase
PAILFIKI_00432	1.32e-111	yvgO	-	-	-	-	-	-	-
PAILFIKI_00433	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
PAILFIKI_00434	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PAILFIKI_00435	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PAILFIKI_00436	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PAILFIKI_00437	1.3e-138	yvgT	-	-	S	-	-	-	membrane
PAILFIKI_00438	1.1e-189	-	-	-	S	-	-	-	Metallo-peptidase family M12
PAILFIKI_00439	3.05e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
PAILFIKI_00440	1.84e-137	bdbD	-	-	O	-	-	-	Thioredoxin
PAILFIKI_00441	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
PAILFIKI_00442	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PAILFIKI_00443	1.88e-39	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
PAILFIKI_00444	2.81e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
PAILFIKI_00445	9.62e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
PAILFIKI_00446	1.03e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PAILFIKI_00447	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAILFIKI_00448	3.52e-62	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
PAILFIKI_00449	3.54e-232	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAILFIKI_00450	8.64e-179	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
PAILFIKI_00451	2.36e-155	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PAILFIKI_00452	7.29e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PAILFIKI_00453	2.91e-187	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
PAILFIKI_00454	5.65e-166	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
PAILFIKI_00455	3.69e-129	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PAILFIKI_00456	3.82e-204	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
PAILFIKI_00457	1.13e-179	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAILFIKI_00459	1.88e-06	-	-	-	L	-	-	-	AAA ATPase domain
PAILFIKI_00462	1.06e-39	-	-	-	S	-	-	-	Phage integrase family
PAILFIKI_00464	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PAILFIKI_00465	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PAILFIKI_00466	1.7e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
PAILFIKI_00467	4.58e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
PAILFIKI_00468	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
PAILFIKI_00469	9.53e-93	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
PAILFIKI_00470	3.52e-96	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
PAILFIKI_00471	2.44e-69	yvaP	-	-	K	-	-	-	transcriptional
PAILFIKI_00472	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
PAILFIKI_00473	1.34e-158	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
PAILFIKI_00474	6.04e-173	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
PAILFIKI_00475	1.15e-155	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
PAILFIKI_00476	1.55e-161	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_00477	2.09e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
PAILFIKI_00478	1.8e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PAILFIKI_00479	3.4e-146	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
PAILFIKI_00480	1.66e-267	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PAILFIKI_00481	3.42e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
PAILFIKI_00482	6.21e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
PAILFIKI_00483	4.61e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PAILFIKI_00484	6.76e-88	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
PAILFIKI_00485	6.61e-30	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
PAILFIKI_00486	5.16e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PAILFIKI_00487	6.82e-128	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
PAILFIKI_00488	1.88e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
PAILFIKI_00489	7.3e-155	yvbI	-	-	M	-	-	-	Membrane
PAILFIKI_00490	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
PAILFIKI_00491	1.29e-105	yvbK	-	-	K	-	-	-	acetyltransferase
PAILFIKI_00492	2.56e-268	-	-	-	EGP	-	-	-	Major facilitator Superfamily
PAILFIKI_00493	4.84e-229	-	-	-	-	-	-	-	-
PAILFIKI_00494	1.9e-163	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
PAILFIKI_00495	2.89e-185	-	-	-	C	-	-	-	WbqC-like protein family
PAILFIKI_00496	2.95e-187	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
PAILFIKI_00497	8.99e-293	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PAILFIKI_00498	2.36e-217	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
PAILFIKI_00499	1.83e-277	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
PAILFIKI_00500	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PAILFIKI_00501	1.63e-301	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
PAILFIKI_00502	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PAILFIKI_00503	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
PAILFIKI_00504	2.58e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PAILFIKI_00505	6.6e-276	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PAILFIKI_00506	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PAILFIKI_00507	3.44e-239	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PAILFIKI_00509	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PAILFIKI_00510	4.51e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
PAILFIKI_00511	1.08e-242	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAILFIKI_00513	1.24e-199	yvbU	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00514	6.36e-204	yvbV	-	-	EG	-	-	-	EamA-like transporter family
PAILFIKI_00515	4.71e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
PAILFIKI_00516	1.51e-232	yhjM	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00517	2.47e-146	-	-	-	S	ko:K07149	-	ko00000	Membrane
PAILFIKI_00518	1.79e-214	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
PAILFIKI_00519	1.9e-195	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
PAILFIKI_00520	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PAILFIKI_00521	1.37e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
PAILFIKI_00523	1.44e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PAILFIKI_00524	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PAILFIKI_00525	3.55e-172	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PAILFIKI_00526	3.57e-281	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAILFIKI_00527	3.62e-155	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
PAILFIKI_00528	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
PAILFIKI_00529	2.67e-308	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PAILFIKI_00530	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
PAILFIKI_00531	2.24e-237	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
PAILFIKI_00532	1.11e-281	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
PAILFIKI_00533	7.66e-77	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
PAILFIKI_00534	2.73e-140	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PAILFIKI_00535	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAILFIKI_00536	2.46e-248	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
PAILFIKI_00537	4.86e-247	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
PAILFIKI_00538	6.27e-247	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
PAILFIKI_00539	3.44e-262	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
PAILFIKI_00540	4.98e-272	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PAILFIKI_00541	2.74e-206	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
PAILFIKI_00542	1.23e-277	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
PAILFIKI_00543	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
PAILFIKI_00544	7.67e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
PAILFIKI_00545	1.17e-155	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
PAILFIKI_00546	1.99e-99	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
PAILFIKI_00547	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
PAILFIKI_00548	2.32e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
PAILFIKI_00549	4.16e-143	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
PAILFIKI_00550	1.9e-119	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAILFIKI_00551	1.01e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
PAILFIKI_00553	4.22e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
PAILFIKI_00554	2.29e-52	-	-	-	I	-	-	-	Pfam Lipase (class 3)
PAILFIKI_00555	5e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
PAILFIKI_00556	0.0	-	-	-	I	-	-	-	Pfam Lipase (class 3)
PAILFIKI_00557	1.31e-45	-	-	-	-	-	-	-	-
PAILFIKI_00559	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PAILFIKI_00560	4.05e-285	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
PAILFIKI_00561	3.17e-234	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
PAILFIKI_00562	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PAILFIKI_00563	4.27e-120	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PAILFIKI_00564	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
PAILFIKI_00565	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
PAILFIKI_00566	3.08e-137	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
PAILFIKI_00567	5.29e-178	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
PAILFIKI_00568	1.1e-279	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
PAILFIKI_00569	1.49e-261	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
PAILFIKI_00570	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
PAILFIKI_00571	2.2e-205	yvdE	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00572	8.57e-134	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
PAILFIKI_00573	1.3e-69	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
PAILFIKI_00574	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
PAILFIKI_00575	4.41e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
PAILFIKI_00576	1.69e-232	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAILFIKI_00577	5.54e-105	-	-	-	M	-	-	-	Ribonuclease
PAILFIKI_00578	1.66e-159	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
PAILFIKI_00579	3.23e-49	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
PAILFIKI_00580	7.32e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PAILFIKI_00581	1.28e-225	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PAILFIKI_00582	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PAILFIKI_00583	2.98e-112	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PAILFIKI_00584	3.13e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PAILFIKI_00585	1.19e-78	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
PAILFIKI_00586	6.59e-109	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
PAILFIKI_00587	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
PAILFIKI_00588	1.36e-245	sasA	-	-	T	-	-	-	Histidine kinase
PAILFIKI_00589	3.82e-156	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_00590	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PAILFIKI_00591	9.88e-145	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
PAILFIKI_00592	8e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PAILFIKI_00593	2.67e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PAILFIKI_00594	9.83e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PAILFIKI_00595	1.17e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
PAILFIKI_00596	2.72e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PAILFIKI_00597	2.14e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PAILFIKI_00598	1.22e-269	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PAILFIKI_00599	5.06e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
PAILFIKI_00600	5.93e-111	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
PAILFIKI_00601	9.48e-157	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PAILFIKI_00602	5.27e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PAILFIKI_00603	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PAILFIKI_00604	3.89e-285	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PAILFIKI_00605	6.1e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PAILFIKI_00606	2.13e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
PAILFIKI_00607	1.27e-135	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
PAILFIKI_00608	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
PAILFIKI_00609	7.66e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
PAILFIKI_00610	4.01e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
PAILFIKI_00611	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
PAILFIKI_00612	4.87e-66	yvlA	-	-	-	-	-	-	-
PAILFIKI_00613	3.29e-43	yvkN	-	-	-	-	-	-	-
PAILFIKI_00614	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PAILFIKI_00615	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PAILFIKI_00616	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_00617	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
PAILFIKI_00618	2.32e-144	yvkB	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00619	2.93e-298	yvkA	-	-	P	-	-	-	-transporter
PAILFIKI_00622	9.44e-240	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PAILFIKI_00623	7.21e-281	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAILFIKI_00624	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
PAILFIKI_00625	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
PAILFIKI_00626	7.31e-306	ywoF	-	-	P	-	-	-	Right handed beta helix region
PAILFIKI_00627	2.48e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PAILFIKI_00628	8.68e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
PAILFIKI_00629	5.11e-59	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
PAILFIKI_00630	6.85e-192	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PAILFIKI_00631	6.64e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PAILFIKI_00632	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PAILFIKI_00633	2.28e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PAILFIKI_00634	1.35e-89	-	-	-	-	-	-	-	-
PAILFIKI_00635	4.35e-10	fliT	-	-	N	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
PAILFIKI_00636	5.79e-88	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
PAILFIKI_00637	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PAILFIKI_00638	6.97e-153	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PAILFIKI_00639	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PAILFIKI_00640	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PAILFIKI_00641	2.8e-108	yviE	-	-	-	-	-	-	-
PAILFIKI_00642	1.4e-207	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
PAILFIKI_00643	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
PAILFIKI_00644	3.64e-104	yvyG	-	-	NOU	-	-	-	FlgN protein
PAILFIKI_00645	6.14e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
PAILFIKI_00646	5.47e-98	yvyF	-	-	S	-	-	-	flagellar protein
PAILFIKI_00647	1.01e-99	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
PAILFIKI_00648	3.56e-57	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
PAILFIKI_00649	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PAILFIKI_00650	1.03e-202	degV	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_00651	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAILFIKI_00652	3.44e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PAILFIKI_00653	2.94e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
PAILFIKI_00654	1.16e-235	yvhJ	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00655	3.12e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PAILFIKI_00656	4.67e-303	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
PAILFIKI_00657	4.68e-184	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
PAILFIKI_00658	3.49e-148	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
PAILFIKI_00659	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
PAILFIKI_00660	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PAILFIKI_00661	4.87e-280	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
PAILFIKI_00662	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAILFIKI_00663	4.92e-150	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PAILFIKI_00664	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
PAILFIKI_00665	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
PAILFIKI_00666	1.86e-64	-	-	-	-	-	-	-	-
PAILFIKI_00667	4.48e-204	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PAILFIKI_00668	2.86e-267	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PAILFIKI_00669	2.64e-211	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PAILFIKI_00670	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PAILFIKI_00671	1.45e-194	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
PAILFIKI_00672	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PAILFIKI_00673	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PAILFIKI_00674	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
PAILFIKI_00675	2.13e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PAILFIKI_00676	2.57e-272	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PAILFIKI_00677	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PAILFIKI_00678	1.07e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PAILFIKI_00679	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
PAILFIKI_00680	1.66e-249	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
PAILFIKI_00681	8.96e-274	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
PAILFIKI_00682	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
PAILFIKI_00683	1.99e-314	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PAILFIKI_00684	1.14e-229	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00685	6.43e-203	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
PAILFIKI_00686	6.84e-74	yttA	-	-	S	-	-	-	Pfam Transposase IS66
PAILFIKI_00687	6.43e-303	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PAILFIKI_00688	4.04e-29	ywtC	-	-	-	-	-	-	-
PAILFIKI_00689	1.39e-280	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PAILFIKI_00690	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
PAILFIKI_00691	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
PAILFIKI_00692	1.26e-241	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
PAILFIKI_00693	3.58e-229	-	-	-	E	-	-	-	Spore germination protein
PAILFIKI_00694	5.06e-260	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
PAILFIKI_00695	3.66e-229	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
PAILFIKI_00696	2.94e-203	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAILFIKI_00697	1.38e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PAILFIKI_00698	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PAILFIKI_00699	4.4e-204	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PAILFIKI_00700	1.15e-206	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
PAILFIKI_00701	2.39e-115	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
PAILFIKI_00702	1.75e-123	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
PAILFIKI_00703	5.71e-191	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
PAILFIKI_00704	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PAILFIKI_00705	5.35e-215	alsR	-	-	K	-	-	-	LysR substrate binding domain
PAILFIKI_00707	1.04e-306	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PAILFIKI_00708	3.43e-163	ywrJ	-	-	-	-	-	-	-
PAILFIKI_00709	2.49e-183	cotB	-	-	-	ko:K06325	-	ko00000	-
PAILFIKI_00710	1.5e-226	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
PAILFIKI_00711	6.3e-22	-	-	-	-	-	-	-	-
PAILFIKI_00712	2.33e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PAILFIKI_00714	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
PAILFIKI_00715	3.53e-110	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
PAILFIKI_00716	2e-130	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
PAILFIKI_00717	2.47e-113	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
PAILFIKI_00719	2.58e-121	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
PAILFIKI_00720	5.92e-203	-	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00721	4.84e-170	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
PAILFIKI_00722	7.58e-123	-	-	-	-	-	-	-	-
PAILFIKI_00724	1.66e-65	-	-	-	-	-	-	-	-
PAILFIKI_00725	5.28e-113	-	-	-	-	-	-	-	-
PAILFIKI_00726	0.0	ywqJ	-	-	S	-	-	-	Pre-toxin TG
PAILFIKI_00727	2.97e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
PAILFIKI_00730	1.2e-191	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
PAILFIKI_00731	8.72e-314	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PAILFIKI_00732	5.03e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
PAILFIKI_00733	2.12e-155	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
PAILFIKI_00734	8.29e-151	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
PAILFIKI_00735	1.74e-21	-	-	-	-	-	-	-	-
PAILFIKI_00736	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
PAILFIKI_00737	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
PAILFIKI_00738	1.51e-201	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
PAILFIKI_00739	1.18e-181	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PAILFIKI_00740	1.47e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
PAILFIKI_00741	4.49e-82	ywpG	-	-	-	-	-	-	-
PAILFIKI_00742	1.52e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
PAILFIKI_00743	1.66e-62	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PAILFIKI_00744	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PAILFIKI_00745	1.34e-257	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
PAILFIKI_00746	4.45e-186	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
PAILFIKI_00747	2e-171	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
PAILFIKI_00748	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
PAILFIKI_00749	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
PAILFIKI_00750	3.58e-93	ywoH	-	-	K	-	-	-	transcriptional
PAILFIKI_00751	4.1e-272	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_00752	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
PAILFIKI_00753	2.31e-311	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
PAILFIKI_00754	1.13e-132	yjgF	-	-	Q	-	-	-	Isochorismatase family
PAILFIKI_00755	1.32e-291	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
PAILFIKI_00756	1.07e-75	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
PAILFIKI_00757	1.72e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PAILFIKI_00758	1.17e-131	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
PAILFIKI_00759	4.67e-95	ywnJ	-	-	S	-	-	-	VanZ like family
PAILFIKI_00760	2.17e-187	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
PAILFIKI_00761	2.76e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
PAILFIKI_00763	6.01e-89	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
PAILFIKI_00764	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAILFIKI_00765	6.88e-80	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
PAILFIKI_00766	5.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
PAILFIKI_00768	3.61e-87	ywnA	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00769	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PAILFIKI_00770	1.07e-81	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
PAILFIKI_00771	2.86e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
PAILFIKI_00772	2.01e-16	csbD	-	-	K	-	-	-	CsbD-like
PAILFIKI_00773	3.66e-108	ywmF	-	-	S	-	-	-	Peptidase M50
PAILFIKI_00774	6.28e-116	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
PAILFIKI_00775	3.1e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PAILFIKI_00776	1.06e-185	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PAILFIKI_00778	1.5e-158	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
PAILFIKI_00779	2.59e-160	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
PAILFIKI_00780	4.93e-243	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
PAILFIKI_00781	7.05e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAILFIKI_00782	8.35e-175	ywmB	-	-	S	-	-	-	TATA-box binding
PAILFIKI_00783	2.25e-45	ywzB	-	-	S	-	-	-	membrane
PAILFIKI_00784	4.15e-117	ywmA	-	-	-	-	-	-	-
PAILFIKI_00785	8.24e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PAILFIKI_00786	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PAILFIKI_00787	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PAILFIKI_00788	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PAILFIKI_00789	2.77e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PAILFIKI_00790	1.66e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PAILFIKI_00791	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PAILFIKI_00792	3e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PAILFIKI_00793	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
PAILFIKI_00794	6.42e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PAILFIKI_00795	1.99e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PAILFIKI_00796	3.68e-125	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
PAILFIKI_00797	6.74e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
PAILFIKI_00798	1.2e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAILFIKI_00799	1.36e-118	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
PAILFIKI_00800	3.6e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PAILFIKI_00801	2.02e-97	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
PAILFIKI_00802	1.88e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
PAILFIKI_00803	1.71e-78	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
PAILFIKI_00804	1.4e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PAILFIKI_00805	1.11e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PAILFIKI_00806	6.14e-87	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAILFIKI_00807	8.54e-123	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PAILFIKI_00808	2.02e-202	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PAILFIKI_00809	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
PAILFIKI_00810	5.56e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PAILFIKI_00811	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
PAILFIKI_00812	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PAILFIKI_00813	1.43e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
PAILFIKI_00814	5.55e-304	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAILFIKI_00815	2.22e-144	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PAILFIKI_00816	5.51e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
PAILFIKI_00817	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
PAILFIKI_00818	6.67e-120	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
PAILFIKI_00819	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PAILFIKI_00820	8.4e-76	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PAILFIKI_00821	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
PAILFIKI_00822	6.69e-283	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PAILFIKI_00823	8.09e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PAILFIKI_00824	1.13e-58	ywjC	-	-	-	-	-	-	-
PAILFIKI_00825	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PAILFIKI_00826	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAILFIKI_00827	3.02e-136	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAILFIKI_00828	2.41e-158	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
PAILFIKI_00829	1.48e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
PAILFIKI_00830	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
PAILFIKI_00831	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAILFIKI_00832	2.91e-109	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
PAILFIKI_00833	5.69e-22	ywiC	-	-	S	-	-	-	YwiC-like protein
PAILFIKI_00834	5.43e-167	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
PAILFIKI_00835	4.27e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
PAILFIKI_00836	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PAILFIKI_00837	2.21e-94	ywiB	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_00839	5.82e-307	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
PAILFIKI_00840	3.01e-294	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
PAILFIKI_00841	1.38e-103	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
PAILFIKI_00843	1.73e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
PAILFIKI_00844	1.58e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PAILFIKI_00845	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PAILFIKI_00846	1.23e-69	-	-	-	-	-	-	-	-
PAILFIKI_00847	1.32e-14	-	-	-	-	-	-	-	-
PAILFIKI_00848	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
PAILFIKI_00849	3.84e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
PAILFIKI_00850	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
PAILFIKI_00851	4.16e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00852	9.94e-316	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
PAILFIKI_00853	2.02e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
PAILFIKI_00854	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
PAILFIKI_00855	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
PAILFIKI_00856	2.48e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
PAILFIKI_00857	1.08e-67	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
PAILFIKI_00858	3.78e-120	-	-	-	S	-	-	-	membrane
PAILFIKI_00859	1.65e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_00860	1.79e-216	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
PAILFIKI_00863	1.51e-234	-	-	-	-	-	-	-	-
PAILFIKI_00865	8.76e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PAILFIKI_00866	4.54e-210	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_00867	9.79e-213	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PAILFIKI_00868	2.03e-225	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
PAILFIKI_00869	4.87e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
PAILFIKI_00870	2.94e-181	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
PAILFIKI_00871	2.21e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
PAILFIKI_00872	8.14e-265	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
PAILFIKI_00873	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PAILFIKI_00874	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAILFIKI_00875	1.19e-176	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PAILFIKI_00876	3.85e-144	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PAILFIKI_00877	1.11e-283	ywfA	-	-	EGP	-	-	-	-transporter
PAILFIKI_00878	2.43e-265	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
PAILFIKI_00879	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PAILFIKI_00880	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
PAILFIKI_00881	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
PAILFIKI_00882	3.15e-314	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
PAILFIKI_00883	2.04e-203	-	-	-	T	-	-	-	Histidine kinase
PAILFIKI_00884	6.09e-161	-	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_00885	2.37e-96	-	-	-	-	-	-	-	-
PAILFIKI_00886	1.48e-153	-	-	-	S	-	-	-	ABC-2 family transporter protein
PAILFIKI_00887	1.32e-221	bcrA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_00888	1.15e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
PAILFIKI_00889	4.55e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PAILFIKI_00890	6.14e-232	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PAILFIKI_00891	1.63e-176	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PAILFIKI_00892	5.91e-235	spsG	-	-	M	-	-	-	Spore Coat
PAILFIKI_00893	7.11e-172	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
PAILFIKI_00894	7.09e-274	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
PAILFIKI_00895	6.71e-206	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
PAILFIKI_00896	3.57e-282	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
PAILFIKI_00897	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
PAILFIKI_00898	5.24e-183	spsA	-	-	M	-	-	-	Spore Coat
PAILFIKI_00899	6.51e-88	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PAILFIKI_00900	2.17e-76	ywdK	-	-	S	-	-	-	small membrane protein
PAILFIKI_00901	5.38e-291	ywdJ	-	-	F	-	-	-	Xanthine uracil
PAILFIKI_00902	1.06e-60	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
PAILFIKI_00903	7.22e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PAILFIKI_00904	3.29e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
PAILFIKI_00906	7.67e-85	ywdD	-	-	-	-	-	-	-
PAILFIKI_00908	1.32e-74	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
PAILFIKI_00909	3.39e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PAILFIKI_00910	3.52e-26	ywdA	-	-	-	-	-	-	-
PAILFIKI_00911	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PAILFIKI_00912	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_00913	4.68e-196	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
PAILFIKI_00915	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PAILFIKI_00916	1.34e-235	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAILFIKI_00917	1.14e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
PAILFIKI_00918	7.63e-271	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PAILFIKI_00919	1.24e-99	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
PAILFIKI_00920	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
PAILFIKI_00921	6.76e-84	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
PAILFIKI_00922	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
PAILFIKI_00923	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PAILFIKI_00924	3.14e-228	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PAILFIKI_00925	5.74e-48	ydaS	-	-	S	-	-	-	membrane
PAILFIKI_00926	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PAILFIKI_00927	4.22e-288	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PAILFIKI_00928	2e-80	gtcA	-	-	S	-	-	-	GtrA-like protein
PAILFIKI_00929	6.43e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PAILFIKI_00931	7.2e-166	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
PAILFIKI_00932	1.58e-168	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
PAILFIKI_00933	3.09e-145	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
PAILFIKI_00934	5.15e-308	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
PAILFIKI_00935	5.8e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PAILFIKI_00936	1.02e-172	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PAILFIKI_00937	4.83e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_00938	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PAILFIKI_00939	6.47e-144	ywbG	-	-	M	-	-	-	effector of murein hydrolase
PAILFIKI_00940	9.1e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
PAILFIKI_00941	1.01e-174	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
PAILFIKI_00942	9.24e-217	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
PAILFIKI_00943	5.11e-285	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
PAILFIKI_00944	1.06e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
PAILFIKI_00945	2.71e-314	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAILFIKI_00946	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PAILFIKI_00947	3.64e-208	gspA	-	-	M	-	-	-	General stress
PAILFIKI_00948	1.85e-151	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
PAILFIKI_00949	7.57e-215	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
PAILFIKI_00950	7.08e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PAILFIKI_00951	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_00952	2.56e-293	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
PAILFIKI_00953	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_00954	4.21e-287	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PAILFIKI_00955	1.35e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
PAILFIKI_00956	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PAILFIKI_00957	1.18e-67	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_00958	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAILFIKI_00959	4.46e-66	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
PAILFIKI_00960	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
PAILFIKI_00961	1.08e-143	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PAILFIKI_00962	4.69e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAILFIKI_00963	1.38e-230	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAILFIKI_00964	7.58e-213	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
PAILFIKI_00965	6.17e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
PAILFIKI_00966	6.3e-291	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PAILFIKI_00967	1.18e-66	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_00968	3.22e-65	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_00969	6.11e-237	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAILFIKI_00970	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PAILFIKI_00971	1.93e-139	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
PAILFIKI_00972	1.27e-29	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
PAILFIKI_00973	1.58e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PAILFIKI_00974	8.82e-266	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
PAILFIKI_00975	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
PAILFIKI_00976	8.52e-314	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
PAILFIKI_00978	1.81e-127	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PAILFIKI_00981	6.64e-05	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
PAILFIKI_00983	0.00047	-	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
PAILFIKI_00984	5.75e-131	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PAILFIKI_00985	3.43e-77	-	-	-	S	-	-	-	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PAILFIKI_00986	3.07e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PAILFIKI_00987	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
PAILFIKI_00988	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
PAILFIKI_00989	1.12e-241	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
PAILFIKI_00990	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
PAILFIKI_00991	3.19e-287	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
PAILFIKI_00992	8.1e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
PAILFIKI_00993	2.62e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_00994	2.63e-208	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
PAILFIKI_00995	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAILFIKI_00996	2.68e-120	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
PAILFIKI_00997	2.28e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PAILFIKI_00998	6.94e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PAILFIKI_01001	6.11e-111	yxjI	-	-	S	-	-	-	LURP-one-related
PAILFIKI_01002	6.59e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
PAILFIKI_01003	1.83e-163	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
PAILFIKI_01004	9.51e-267	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PAILFIKI_01005	8.8e-125	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
PAILFIKI_01006	2.68e-67	yxiS	-	-	-	-	-	-	-
PAILFIKI_01007	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
PAILFIKI_01008	1.35e-282	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
PAILFIKI_01009	1.91e-183	bglS	-	-	M	-	-	-	licheninase activity
PAILFIKI_01010	1e-279	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
PAILFIKI_01011	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PAILFIKI_01012	1.05e-254	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
PAILFIKI_01013	8.44e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
PAILFIKI_01014	1.41e-93	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
PAILFIKI_01017	7.64e-53	-	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01019	4.69e-39	-	-	-	-	-	-	-	-
PAILFIKI_01020	5.71e-130	-	-	-	L	-	-	-	Replication protein
PAILFIKI_01021	1.86e-18	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
PAILFIKI_01022	5.59e-58	-	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
PAILFIKI_01023	3.9e-232	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
PAILFIKI_01024	4.36e-225	-	-	-	L	-	-	-	AlwI restriction endonuclease
PAILFIKI_01026	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
PAILFIKI_01027	2.45e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
PAILFIKI_01028	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
PAILFIKI_01029	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PAILFIKI_01030	3.7e-298	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
PAILFIKI_01031	1.32e-222	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
PAILFIKI_01032	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PAILFIKI_01033	1.1e-296	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
PAILFIKI_01034	4.04e-265	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PAILFIKI_01035	1.17e-144	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PAILFIKI_01036	1.12e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PAILFIKI_01037	2.32e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
PAILFIKI_01040	9.43e-34	yxeE	-	-	-	-	-	-	-
PAILFIKI_01041	6.89e-08	yxeD	-	-	-	-	-	-	-
PAILFIKI_01042	2.27e-08	-	-	-	L	-	-	-	Helix-hairpin-helix motif
PAILFIKI_01043	1.61e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
PAILFIKI_01044	4.9e-76	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PAILFIKI_01045	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
PAILFIKI_01046	6.61e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_01047	4.59e-223	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_01048	1.09e-157	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_01049	0.0	-	-	-	T	-	-	-	Histidine kinase
PAILFIKI_01050	1.51e-174	yvrH	-	-	T	-	-	-	Transcriptional regulator
PAILFIKI_01051	7.54e-211	-	-	-	V	ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_01052	9.21e-166	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	permease
PAILFIKI_01053	1.05e-167	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
PAILFIKI_01054	1.35e-202	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PAILFIKI_01055	2.68e-192	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PAILFIKI_01056	6.24e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
PAILFIKI_01057	6.3e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PAILFIKI_01058	1.23e-292	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
PAILFIKI_01059	4.62e-223	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PAILFIKI_01060	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PAILFIKI_01061	5.42e-229	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PAILFIKI_01062	3.45e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PAILFIKI_01063	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PAILFIKI_01064	6.09e-175	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
PAILFIKI_01065	3.94e-221	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
PAILFIKI_01066	4.5e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PAILFIKI_01067	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
PAILFIKI_01069	5.9e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
PAILFIKI_01070	3.72e-132	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAILFIKI_01071	4.12e-255	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_01072	1.01e-254	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
PAILFIKI_01073	5.42e-275	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PAILFIKI_01074	0.0	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PAILFIKI_01075	1.58e-187	yxaL	-	-	S	-	-	-	PQQ-like domain
PAILFIKI_01076	2.5e-85	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
PAILFIKI_01077	1.21e-67	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PAILFIKI_01078	7.67e-256	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PAILFIKI_01079	7.8e-97	yxaI	-	-	S	-	-	-	membrane protein domain
PAILFIKI_01080	1.9e-153	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
PAILFIKI_01081	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
PAILFIKI_01082	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
PAILFIKI_01083	3.95e-292	-	-	-	S	-	-	-	Fic/DOC family
PAILFIKI_01084	1.51e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
PAILFIKI_01085	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
PAILFIKI_01086	4.92e-110	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PAILFIKI_01087	1.91e-197	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PAILFIKI_01088	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PAILFIKI_01089	3.46e-77	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PAILFIKI_01090	3.73e-119	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
PAILFIKI_01091	1.03e-237	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PAILFIKI_01092	9.35e-233	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
PAILFIKI_01093	5.2e-26	-	-	-	-	-	-	-	-
PAILFIKI_01094	0.0	-	-	-	L	-	-	-	AAA domain
PAILFIKI_01095	8.08e-97	-	-	-	F	-	-	-	5-carbamoylmethyl uridine residue modification
PAILFIKI_01096	3.12e-116	-	-	-	K	-	-	-	NAD+ binding
PAILFIKI_01097	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PAILFIKI_01100	2.21e-275	yycP	-	-	-	-	-	-	-
PAILFIKI_01101	6.82e-171	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PAILFIKI_01102	6.14e-233	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
PAILFIKI_01103	2.92e-113	yycN	-	-	K	-	-	-	Acetyltransferase
PAILFIKI_01105	9.49e-262	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
PAILFIKI_01106	1.86e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
PAILFIKI_01107	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PAILFIKI_01108	1.95e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
PAILFIKI_01109	1.99e-89	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
PAILFIKI_01110	9.38e-58	sdpR	-	-	K	-	-	-	transcriptional
PAILFIKI_01111	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PAILFIKI_01112	6.44e-189	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
PAILFIKI_01113	0.0	-	-	-	S	-	-	-	ABC transporter
PAILFIKI_01114	4.27e-257	-	-	-	S	-	-	-	Major Facilitator Superfamily
PAILFIKI_01115	0.0	-	-	-	-	-	-	-	-
PAILFIKI_01116	2.31e-243	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
PAILFIKI_01117	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
PAILFIKI_01118	2.5e-14	phoP1	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_01119	1.63e-278	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAILFIKI_01120	5.69e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PAILFIKI_01121	2.81e-194	yycI	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01122	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01123	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_01124	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_01125	1.06e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PAILFIKI_01126	1.57e-94	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAILFIKI_01127	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PAILFIKI_01128	7.68e-39	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
PAILFIKI_01130	5.12e-25	yycC	-	-	K	-	-	-	YycC-like protein
PAILFIKI_01131	1.79e-305	-	-	-	M	-	-	-	Glycosyltransferase Family 4
PAILFIKI_01132	6.38e-259	-	-	-	S	-	-	-	Ecdysteroid kinase
PAILFIKI_01133	6.57e-297	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
PAILFIKI_01134	5.98e-302	-	-	-	M	-	-	-	Glycosyltransferase Family 4
PAILFIKI_01135	2.15e-157	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
PAILFIKI_01136	1.7e-157	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
PAILFIKI_01137	1.58e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
PAILFIKI_01138	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PAILFIKI_01139	1.95e-201	yybS	-	-	S	-	-	-	membrane
PAILFIKI_01141	3.33e-111	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
PAILFIKI_01142	4.56e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01143	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
PAILFIKI_01144	1.02e-197	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PAILFIKI_01145	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
PAILFIKI_01146	3.47e-260	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
PAILFIKI_01147	3.82e-149	-	-	-	K	-	-	-	FCD domain
PAILFIKI_01148	2.63e-115	-	-	-	S	-	-	-	PFAM DinB family protein
PAILFIKI_01149	5.87e-201	-	-	-	G	-	-	-	Major Facilitator Superfamily
PAILFIKI_01150	1.12e-73	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PAILFIKI_01151	1.62e-145	ydgI	-	-	C	-	-	-	nitroreductase
PAILFIKI_01152	2.77e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
PAILFIKI_01153	1.48e-191	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PAILFIKI_01154	1.3e-99	yybA	-	-	K	-	-	-	transcriptional
PAILFIKI_01155	1.49e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PAILFIKI_01156	3.34e-211	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
PAILFIKI_01157	4.76e-87	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PAILFIKI_01158	4.21e-212	-	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01159	2.35e-176	bdh	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PAILFIKI_01160	2.42e-276	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAILFIKI_01161	6.35e-167	-	-	-	EG	-	-	-	EamA-like transporter family
PAILFIKI_01162	9.99e-30	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
PAILFIKI_01163	1.02e-106	-	-	-	-	-	-	-	-
PAILFIKI_01164	4.54e-91	ynaF	-	-	-	-	-	-	-
PAILFIKI_01167	8.35e-30	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
PAILFIKI_01168	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
PAILFIKI_01169	2.84e-208	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PAILFIKI_01170	1.88e-316	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
PAILFIKI_01171	4.88e-88	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAILFIKI_01172	6.62e-230	ccpB	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01173	3.29e-184	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PAILFIKI_01174	3.38e-128	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PAILFIKI_01175	3.63e-136	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
PAILFIKI_01176	4.51e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PAILFIKI_01177	1.37e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PAILFIKI_01178	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PAILFIKI_01179	5.42e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PAILFIKI_01180	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAILFIKI_01181	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01182	4.77e-225	yyaD	-	-	S	-	-	-	Membrane
PAILFIKI_01183	2.62e-105	yhhY	-	-	K	-	-	-	FR47-like protein
PAILFIKI_01184	8.14e-143	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
PAILFIKI_01185	8.27e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PAILFIKI_01186	1.23e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
PAILFIKI_01187	1.1e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PAILFIKI_01188	2.29e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PAILFIKI_01189	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PAILFIKI_01190	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PAILFIKI_01191	7.7e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
PAILFIKI_01192	2.12e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PAILFIKI_01193	1.99e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PAILFIKI_01195	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PAILFIKI_01196	8.47e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PAILFIKI_01197	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
PAILFIKI_01198	3.2e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PAILFIKI_01199	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
PAILFIKI_01200	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAILFIKI_01201	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAILFIKI_01202	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_01203	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_01205	6.87e-277	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
PAILFIKI_01206	1.88e-223	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
PAILFIKI_01207	3.12e-90	cgeA	-	-	-	ko:K06319	-	ko00000	-
PAILFIKI_01208	1.64e-62	cgeC	-	-	-	ko:K06321	-	ko00000	-
PAILFIKI_01209	8.84e-316	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
PAILFIKI_01210	5.71e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
PAILFIKI_01212	1.19e-83	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
PAILFIKI_01213	1.69e-312	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAILFIKI_01214	1.19e-161	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PAILFIKI_01215	4.64e-160	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PAILFIKI_01216	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
PAILFIKI_01217	9.87e-204	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
PAILFIKI_01218	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
PAILFIKI_01219	8.13e-62	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
PAILFIKI_01220	2.45e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PAILFIKI_01221	1.9e-161	yodN	-	-	-	-	-	-	-
PAILFIKI_01223	9.77e-34	yozD	-	-	S	-	-	-	YozD-like protein
PAILFIKI_01224	5.88e-131	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
PAILFIKI_01225	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
PAILFIKI_01227	1.05e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
PAILFIKI_01228	7.76e-193	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
PAILFIKI_01229	6.87e-50	yodI	-	-	-	-	-	-	-
PAILFIKI_01230	6.12e-166	yodH	-	-	Q	-	-	-	Methyltransferase
PAILFIKI_01231	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
PAILFIKI_01232	5.86e-168	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_01233	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PAILFIKI_01234	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
PAILFIKI_01235	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAILFIKI_01236	1.97e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
PAILFIKI_01237	1.09e-221	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
PAILFIKI_01238	2.43e-140	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
PAILFIKI_01239	1.35e-138	yodC	-	-	C	-	-	-	nitroreductase
PAILFIKI_01240	1.2e-74	yodB	-	-	K	-	-	-	transcriptional
PAILFIKI_01241	2.74e-92	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
PAILFIKI_01242	1.5e-88	iolK	-	-	S	-	-	-	tautomerase
PAILFIKI_01244	4.87e-106	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
PAILFIKI_01245	4.91e-209	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
PAILFIKI_01246	5.2e-31	-	-	-	-	-	-	-	-
PAILFIKI_01247	8.09e-80	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
PAILFIKI_01248	1.57e-162	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
PAILFIKI_01249	1.68e-192	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PAILFIKI_01250	2.39e-310	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
PAILFIKI_01252	4.5e-142	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PAILFIKI_01253	1.13e-276	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
PAILFIKI_01254	3.47e-287	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
PAILFIKI_01255	6.26e-143	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PAILFIKI_01256	4.2e-209	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
PAILFIKI_01257	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
PAILFIKI_01258	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PAILFIKI_01259	7.41e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PAILFIKI_01260	1.98e-179	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
PAILFIKI_01261	1.06e-197	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
PAILFIKI_01262	4.17e-298	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PAILFIKI_01263	8.22e-213	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
PAILFIKI_01264	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
PAILFIKI_01265	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PAILFIKI_01266	1.11e-41	yozC	-	-	-	-	-	-	-
PAILFIKI_01268	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
PAILFIKI_01269	6.36e-50	yocN	-	-	-	-	-	-	-
PAILFIKI_01270	1.87e-57	yozN	-	-	-	-	-	-	-
PAILFIKI_01271	2.29e-116	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PAILFIKI_01272	4.98e-13	yocN	-	-	-	-	-	-	-
PAILFIKI_01273	2.71e-13	yocL	-	-	-	-	-	-	-
PAILFIKI_01274	4.5e-79	yocK	-	-	T	-	-	-	general stress protein
PAILFIKI_01276	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PAILFIKI_01277	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
PAILFIKI_01278	9.79e-168	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
PAILFIKI_01280	3.27e-237	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
PAILFIKI_01281	2.27e-123	yocC	-	-	-	-	-	-	-
PAILFIKI_01282	4.8e-179	-	-	-	J	-	-	-	Protein required for attachment to host cells
PAILFIKI_01283	8.99e-116	yozB	-	-	S	ko:K08976	-	ko00000	membrane
PAILFIKI_01284	1.19e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PAILFIKI_01285	6.33e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
PAILFIKI_01286	1.57e-118	yobW	-	-	-	-	-	-	-
PAILFIKI_01287	1.98e-174	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
PAILFIKI_01288	8.84e-121	yobS	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01289	9.78e-169	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PAILFIKI_01290	1.05e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
PAILFIKI_01291	7.11e-224	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PAILFIKI_01292	3.25e-72	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
PAILFIKI_01293	5.5e-56	-	-	-	-	-	-	-	-
PAILFIKI_01294	1.63e-128	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PAILFIKI_01296	2.99e-22	yoaF	-	-	-	-	-	-	-
PAILFIKI_01297	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAILFIKI_01298	4.74e-243	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAILFIKI_01299	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
PAILFIKI_01300	1.1e-261	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
PAILFIKI_01301	2.12e-176	yoxB	-	-	-	-	-	-	-
PAILFIKI_01302	3.03e-50	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PAILFIKI_01303	1.73e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAILFIKI_01304	8.13e-82	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PAILFIKI_01305	3.42e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAILFIKI_01306	2.82e-259	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PAILFIKI_01307	7.8e-207	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_01308	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
PAILFIKI_01309	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PAILFIKI_01310	1.77e-239	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PAILFIKI_01311	2.6e-199	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_01312	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PAILFIKI_01313	3.29e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
PAILFIKI_01314	1.95e-255	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
PAILFIKI_01315	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
PAILFIKI_01316	6.69e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
PAILFIKI_01317	3.97e-125	-	-	-	L	-	-	-	Integrase
PAILFIKI_01320	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PAILFIKI_01321	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PAILFIKI_01322	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PAILFIKI_01323	7.18e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01324	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PAILFIKI_01325	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PAILFIKI_01326	2.14e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PAILFIKI_01327	1.42e-138	-	-	-	S	-	-	-	ABC-2 family transporter protein
PAILFIKI_01328	8.72e-163	-	-	-	T	ko:K11630	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_01329	2.32e-235	-	-	-	T	ko:K19168	-	ko00000,ko02048	Histidine kinase
PAILFIKI_01330	6.57e-176	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_01331	0.0	-	-	-	V	ko:K02004,ko:K11632	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
PAILFIKI_01332	4.5e-15	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAILFIKI_01333	1.03e-206	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
PAILFIKI_01334	6.05e-135	yxaC	-	-	M	-	-	-	effector of murein hydrolase
PAILFIKI_01335	9.9e-68	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
PAILFIKI_01336	5.62e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PAILFIKI_01337	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
PAILFIKI_01338	1.07e-118	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PAILFIKI_01339	2.38e-253	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
PAILFIKI_01340	2.04e-141	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
PAILFIKI_01341	6.21e-214	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
PAILFIKI_01342	3.18e-263	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
PAILFIKI_01343	1.32e-252	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PAILFIKI_01344	2.34e-35	-	-	-	-	-	-	-	-
PAILFIKI_01345	6.08e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
PAILFIKI_01346	1.01e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
PAILFIKI_01347	4.16e-143	yqeB	-	-	-	-	-	-	-
PAILFIKI_01348	7.84e-55	ybyB	-	-	-	-	-	-	-
PAILFIKI_01349	0.0	ybeC	-	-	E	-	-	-	amino acid
PAILFIKI_01350	5.3e-62	-	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PAILFIKI_01352	6.28e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
PAILFIKI_01353	8.18e-211	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
PAILFIKI_01354	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
PAILFIKI_01355	5.8e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
PAILFIKI_01356	1.66e-266	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
PAILFIKI_01358	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
PAILFIKI_01359	1.14e-25	-	-	-	S	ko:K19169	-	ko00000,ko02048	DNA-sulfur modification-associated
PAILFIKI_01360	8.96e-67	-	-	-	S	ko:K19169	-	ko00000,ko02048	DNA-sulfur modification-associated
PAILFIKI_01362	4.73e-176	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
PAILFIKI_01363	2.1e-71	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
PAILFIKI_01364	1.14e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PAILFIKI_01365	8.67e-255	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
PAILFIKI_01366	1.94e-253	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PAILFIKI_01367	1.56e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PAILFIKI_01368	4.26e-113	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
PAILFIKI_01369	7.49e-195	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PAILFIKI_01370	8.67e-55	ybfN	-	-	-	-	-	-	-
PAILFIKI_01371	5.76e-245	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
PAILFIKI_01372	1.17e-271	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAILFIKI_01373	8.33e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
PAILFIKI_01374	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
PAILFIKI_01375	1.69e-229	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
PAILFIKI_01376	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
PAILFIKI_01377	1.11e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PAILFIKI_01378	1.26e-278	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_01379	5.81e-221	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
PAILFIKI_01380	2.46e-08	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
PAILFIKI_01381	4.85e-35	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
PAILFIKI_01382	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAILFIKI_01383	9.49e-143	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
PAILFIKI_01384	2.06e-233	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
PAILFIKI_01385	1.14e-83	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
PAILFIKI_01386	2.56e-72	ydfQ	-	-	CO	-	-	-	Thioredoxin
PAILFIKI_01387	1.63e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
PAILFIKI_01388	1.44e-99	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
PAILFIKI_01389	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
PAILFIKI_01390	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PAILFIKI_01391	4.24e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PAILFIKI_01392	4.68e-152	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PAILFIKI_01393	1.92e-263	ycbU	-	-	E	-	-	-	Selenocysteine lyase
PAILFIKI_01394	1.68e-311	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
PAILFIKI_01395	1.04e-128	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
PAILFIKI_01396	1.8e-250	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PAILFIKI_01397	3.29e-147	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PAILFIKI_01398	9.7e-252	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
PAILFIKI_01399	6.12e-69	yccK	-	-	C	-	-	-	Aldo keto reductase
PAILFIKI_01400	9e-129	yccK	-	-	C	-	-	-	Aldo keto reductase
PAILFIKI_01401	6.27e-224	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
PAILFIKI_01402	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PAILFIKI_01403	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PAILFIKI_01404	1.79e-121	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
PAILFIKI_01405	5.77e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
PAILFIKI_01406	1.23e-178	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
PAILFIKI_01407	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
PAILFIKI_01408	3.64e-214	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PAILFIKI_01409	5.69e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PAILFIKI_01410	1.19e-174	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PAILFIKI_01411	6.94e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAILFIKI_01412	4.06e-140	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
PAILFIKI_01413	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
PAILFIKI_01414	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
PAILFIKI_01415	2.12e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
PAILFIKI_01416	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
PAILFIKI_01417	4.74e-246	yceH	-	-	P	-	-	-	Belongs to the TelA family
PAILFIKI_01418	2.59e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
PAILFIKI_01419	1.28e-292	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
PAILFIKI_01420	2.45e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
PAILFIKI_01421	2.85e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
PAILFIKI_01422	4.59e-270	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
PAILFIKI_01423	8.03e-294	ycgA	-	-	S	-	-	-	Membrane
PAILFIKI_01424	4.41e-106	ycgB	-	-	-	-	-	-	-
PAILFIKI_01425	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
PAILFIKI_01426	5.7e-32	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
PAILFIKI_01427	6.6e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PAILFIKI_01428	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
PAILFIKI_01429	2.82e-100	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PAILFIKI_01430	1.11e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
PAILFIKI_01431	4.19e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
PAILFIKI_01432	1.15e-314	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
PAILFIKI_01433	3.22e-146	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
PAILFIKI_01434	1.29e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PAILFIKI_01435	2.77e-06	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
PAILFIKI_01436	2.44e-141	tmrB	-	-	S	-	-	-	AAA domain
PAILFIKI_01437	5.46e-188	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
PAILFIKI_01438	2.75e-287	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_01439	1.01e-134	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PAILFIKI_01440	3.29e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
PAILFIKI_01441	8.94e-183	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
PAILFIKI_01442	9.61e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
PAILFIKI_01443	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
PAILFIKI_01444	6.34e-311	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAILFIKI_01445	1.43e-290	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
PAILFIKI_01446	3.33e-242	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PAILFIKI_01447	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
PAILFIKI_01448	3.45e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
PAILFIKI_01449	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PAILFIKI_01450	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAILFIKI_01451	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
PAILFIKI_01452	4.05e-285	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
PAILFIKI_01453	1.73e-290	yciC	-	-	S	-	-	-	GTPases (G3E family)
PAILFIKI_01454	7.17e-281	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PAILFIKI_01455	2.2e-95	yckC	-	-	S	-	-	-	membrane
PAILFIKI_01456	9.5e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
PAILFIKI_01457	1.37e-43	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PAILFIKI_01458	6.79e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
PAILFIKI_01459	1.88e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
PAILFIKI_01460	1.22e-121	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
PAILFIKI_01461	5.21e-138	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
PAILFIKI_01462	4.1e-84	hxlR	-	-	K	-	-	-	transcriptional
PAILFIKI_01464	0.0	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PAILFIKI_01465	1.64e-236	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
PAILFIKI_01466	1.7e-111	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
PAILFIKI_01467	1.04e-212	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
PAILFIKI_01468	0.0	ybeC	-	-	E	-	-	-	amino acid
PAILFIKI_01469	3.63e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01470	4.48e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
PAILFIKI_01471	1.73e-64	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
PAILFIKI_01472	1.23e-276	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
PAILFIKI_01473	1.55e-152	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
PAILFIKI_01474	7.17e-172	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
PAILFIKI_01475	1.29e-246	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
PAILFIKI_01476	2.49e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
PAILFIKI_01478	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
PAILFIKI_01481	1.94e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PAILFIKI_01482	2.67e-153	ydhC	-	-	K	-	-	-	FCD
PAILFIKI_01483	9.74e-209	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Isocitrate/isopropylmalate dehydrogenase
PAILFIKI_01484	1.34e-187	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
PAILFIKI_01485	1.35e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PAILFIKI_01486	2.1e-190	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PAILFIKI_01487	6.89e-192	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PAILFIKI_01488	5.09e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
PAILFIKI_01489	3.66e-157	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PAILFIKI_01490	7.49e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PAILFIKI_01491	3.76e-286	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PAILFIKI_01492	1.59e-267	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
PAILFIKI_01493	6.59e-249	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
PAILFIKI_01494	4.59e-189	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PAILFIKI_01495	7.5e-127	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PAILFIKI_01496	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
PAILFIKI_01497	3.41e-171	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
PAILFIKI_01498	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
PAILFIKI_01499	3.28e-141	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAILFIKI_01500	1.91e-272	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_01501	1.71e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
PAILFIKI_01502	3.35e-84	yraF	-	-	M	-	-	-	Spore coat protein
PAILFIKI_01503	3.04e-282	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PAILFIKI_01504	1.19e-33	yraE	-	-	-	ko:K06440	-	ko00000	-
PAILFIKI_01505	5.09e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
PAILFIKI_01506	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAILFIKI_01507	2.5e-200	ydeK	-	-	EG	-	-	-	-transporter
PAILFIKI_01508	1.2e-132	ydeS	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01509	3.57e-249	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
PAILFIKI_01511	3.59e-147	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_01512	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PAILFIKI_01513	5.68e-281	nhaC_1	-	-	C	-	-	-	antiporter
PAILFIKI_01514	4.93e-85	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
PAILFIKI_01515	9.05e-258	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
PAILFIKI_01516	2.07e-212	-	-	-	S	-	-	-	Sodium Bile acid symporter family
PAILFIKI_01517	1.19e-68	ydeH	-	-	-	-	-	-	-
PAILFIKI_01518	2.9e-254	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
PAILFIKI_01520	3.29e-36	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
PAILFIKI_01521	2.58e-37	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
PAILFIKI_01522	1.88e-98	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
PAILFIKI_01523	1.63e-131	yrkC	-	-	G	-	-	-	Cupin domain
PAILFIKI_01525	9.68e-251	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
PAILFIKI_01526	5.11e-214	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
PAILFIKI_01527	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
PAILFIKI_01530	4.11e-82	-	-	-	G	-	-	-	Cupin domain
PAILFIKI_01531	6.08e-102	-	-	-	S	-	-	-	DinB superfamily
PAILFIKI_01532	1.45e-233	-	-	-	S	-	-	-	Patatin-like phospholipase
PAILFIKI_01533	9.96e-69	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
PAILFIKI_01534	1.48e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
PAILFIKI_01535	8.33e-156	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PAILFIKI_01536	1.7e-151	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PAILFIKI_01537	6.46e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
PAILFIKI_01538	1.6e-251	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
PAILFIKI_01539	3.64e-129	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
PAILFIKI_01540	1.42e-76	-	-	-	P	-	-	-	Rhodanese Homology Domain
PAILFIKI_01541	9.32e-107	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
PAILFIKI_01542	1.53e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01543	8.42e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
PAILFIKI_01544	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
PAILFIKI_01545	1.97e-241	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
PAILFIKI_01546	2.22e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PAILFIKI_01547	4.07e-97	ywnA	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01548	1.59e-85	-	-	-	S	-	-	-	YjbR
PAILFIKI_01549	2.13e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
PAILFIKI_01550	1.41e-93	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
PAILFIKI_01551	1.04e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01552	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
PAILFIKI_01554	3.49e-175	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PAILFIKI_01555	3.81e-56	-	-	-	-	-	-	-	-
PAILFIKI_01557	9.77e-150	-	-	-	S	-	-	-	ATPase (AAA superfamily
PAILFIKI_01563	2.88e-74	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PAILFIKI_01564	1.78e-21	-	-	-	-	-	-	-	-
PAILFIKI_01565	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
PAILFIKI_01566	5.75e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
PAILFIKI_01567	1.61e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAILFIKI_01568	7.1e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PAILFIKI_01569	9.77e-71	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
PAILFIKI_01570	1.25e-241	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
PAILFIKI_01571	1.73e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PAILFIKI_01572	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
PAILFIKI_01573	1.05e-186	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
PAILFIKI_01574	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
PAILFIKI_01575	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PAILFIKI_01576	3.83e-277	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PAILFIKI_01577	1.29e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
PAILFIKI_01578	1.09e-75	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PAILFIKI_01579	2.96e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
PAILFIKI_01580	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
PAILFIKI_01581	1.96e-108	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
PAILFIKI_01582	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PAILFIKI_01583	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PAILFIKI_01584	2.52e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PAILFIKI_01585	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
PAILFIKI_01586	6.66e-159	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAILFIKI_01587	9.35e-14	-	-	-	S	-	-	-	Fur-regulated basic protein A
PAILFIKI_01588	1.13e-15	-	-	-	S	-	-	-	Fur-regulated basic protein B
PAILFIKI_01589	2.15e-261	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
PAILFIKI_01590	5.4e-69	ydbL	-	-	-	-	-	-	-
PAILFIKI_01591	3.47e-167	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PAILFIKI_01592	3.37e-221	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_01593	8.61e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
PAILFIKI_01594	1.59e-286	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAILFIKI_01595	3.67e-153	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
PAILFIKI_01596	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
PAILFIKI_01597	2.58e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PAILFIKI_01598	1.92e-198	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
PAILFIKI_01599	1.01e-79	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
PAILFIKI_01600	2.65e-78	ydbB	-	-	G	-	-	-	Cupin domain
PAILFIKI_01601	1.09e-181	ydbA	-	-	P	-	-	-	EcsC protein family
PAILFIKI_01602	2.87e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
PAILFIKI_01603	5.32e-94	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
PAILFIKI_01604	1.95e-45	ydaT	-	-	-	-	-	-	-
PAILFIKI_01606	1.08e-287	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PAILFIKI_01607	7.45e-54	-	-	-	-	-	-	-	-
PAILFIKI_01608	1.65e-127	-	-	-	-	-	-	-	-
PAILFIKI_01609	2.53e-114	-	-	-	-	-	-	-	-
PAILFIKI_01611	2.69e-12	-	-	-	-	-	-	-	-
PAILFIKI_01613	1.65e-267	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
PAILFIKI_01615	2.27e-101	-	-	-	-	-	-	-	-
PAILFIKI_01616	1.02e-32	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
PAILFIKI_01617	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PAILFIKI_01618	1.04e-74	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
PAILFIKI_01619	0.0	ydaO	-	-	E	-	-	-	amino acid
PAILFIKI_01620	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
PAILFIKI_01621	2.16e-301	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
PAILFIKI_01622	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
PAILFIKI_01623	2.67e-189	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
PAILFIKI_01624	1.34e-256	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PAILFIKI_01625	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PAILFIKI_01626	3.25e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
PAILFIKI_01627	6.54e-63	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
PAILFIKI_01628	2.54e-176	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PAILFIKI_01629	1.83e-101	ydaG	-	-	S	-	-	-	general stress protein
PAILFIKI_01630	1.3e-145	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PAILFIKI_01631	7.9e-125	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
PAILFIKI_01632	9.37e-208	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAILFIKI_01633	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
PAILFIKI_01634	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
PAILFIKI_01635	2.57e-221	ycsN	-	-	S	-	-	-	Oxidoreductase
PAILFIKI_01636	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
PAILFIKI_01637	5.95e-75	yczJ	-	-	S	-	-	-	biosynthesis
PAILFIKI_01639	2.23e-149	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
PAILFIKI_01640	2.69e-166	kipR	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01641	1.03e-241	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
PAILFIKI_01642	2.7e-174	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
PAILFIKI_01643	1.4e-191	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
PAILFIKI_01644	2.66e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
PAILFIKI_01645	8.34e-179	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
PAILFIKI_01646	1.1e-176	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PAILFIKI_01648	1.38e-85	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
PAILFIKI_01649	1.21e-265	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
PAILFIKI_01650	4.11e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PAILFIKI_01651	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
PAILFIKI_01652	1.59e-71	-	-	-	-	-	-	-	-
PAILFIKI_01653	4.26e-138	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
PAILFIKI_01654	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
PAILFIKI_01655	2.05e-131	ycnI	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01656	4.85e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAILFIKI_01657	8.27e-191	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
PAILFIKI_01658	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PAILFIKI_01659	2.17e-287	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAILFIKI_01660	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAILFIKI_01661	2.76e-70	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PAILFIKI_01662	8.02e-59	ycnE	-	-	S	-	-	-	Monooxygenase
PAILFIKI_01663	1.97e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
PAILFIKI_01664	4.47e-197	ycnC	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01665	4.87e-314	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
PAILFIKI_01666	3.24e-222	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
PAILFIKI_01667	4.63e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_01668	1.64e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAILFIKI_01669	3.85e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAILFIKI_01670	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PAILFIKI_01672	1.2e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
PAILFIKI_01673	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
PAILFIKI_01674	2.6e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_01675	6.53e-309	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
PAILFIKI_01676	1.62e-158	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PAILFIKI_01677	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
PAILFIKI_01678	2.3e-275	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
PAILFIKI_01679	2.28e-169	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_01680	6.1e-130	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
PAILFIKI_01681	5.96e-179	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
PAILFIKI_01682	4.43e-120	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAILFIKI_01683	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAILFIKI_01684	1.86e-248	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
PAILFIKI_01685	2.82e-300	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
PAILFIKI_01686	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
PAILFIKI_01688	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
PAILFIKI_01689	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
PAILFIKI_01690	6.81e-100	yclD	-	-	-	-	-	-	-
PAILFIKI_01691	2.83e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
PAILFIKI_01692	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
PAILFIKI_01693	1.4e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PAILFIKI_01694	5.96e-206	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
PAILFIKI_01695	8.63e-121	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PAILFIKI_01696	3.53e-153	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
PAILFIKI_01697	3.24e-168	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
PAILFIKI_01698	3.11e-144	yczE	-	-	S	ko:K07149	-	ko00000	membrane
PAILFIKI_01699	1.3e-167	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
PAILFIKI_01700	5.72e-316	-	-	-	E	-	-	-	Aminotransferase class I and II
PAILFIKI_01701	3.56e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
PAILFIKI_01702	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
PAILFIKI_01703	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_01704	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_01705	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_01706	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_01707	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PAILFIKI_01708	1.9e-279	-	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
PAILFIKI_01709	5.31e-304	-	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
PAILFIKI_01710	1.38e-174	-	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
PAILFIKI_01711	1.95e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAILFIKI_01712	6.83e-224	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
PAILFIKI_01713	2.39e-180	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAILFIKI_01714	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
PAILFIKI_01715	2.58e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PAILFIKI_01716	7.67e-96	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAILFIKI_01718	2.91e-238	yueF	-	-	S	-	-	-	transporter activity
PAILFIKI_01720	9.19e-76	-	-	-	S	-	-	-	YolD-like protein
PAILFIKI_01721	3.1e-177	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PAILFIKI_01722	4.67e-114	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
PAILFIKI_01723	1.71e-80	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
PAILFIKI_01724	1.76e-224	yqkA	-	-	K	-	-	-	GrpB protein
PAILFIKI_01725	2.2e-79	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
PAILFIKI_01726	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
PAILFIKI_01727	2.27e-223	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
PAILFIKI_01728	1.45e-11	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
PAILFIKI_01729	1.08e-216	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
PAILFIKI_01730	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
PAILFIKI_01731	1.04e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
PAILFIKI_01732	6.89e-279	yqxK	-	-	L	-	-	-	DNA helicase
PAILFIKI_01733	1.34e-74	ansR	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01734	1.3e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
PAILFIKI_01735	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
PAILFIKI_01736	2.4e-311	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
PAILFIKI_01737	4.12e-310	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
PAILFIKI_01738	3.39e-31	-	-	-	-	-	-	-	-
PAILFIKI_01739	7.07e-40	yqkK	-	-	-	-	-	-	-
PAILFIKI_01740	3.53e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PAILFIKI_01741	4.56e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PAILFIKI_01742	9.51e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
PAILFIKI_01743	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
PAILFIKI_01744	4.43e-291	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PAILFIKI_01745	1.1e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PAILFIKI_01746	1.43e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PAILFIKI_01747	4.86e-77	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
PAILFIKI_01748	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PAILFIKI_01749	7.94e-173	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAILFIKI_01750	4.63e-130	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
PAILFIKI_01751	2.85e-103	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
PAILFIKI_01752	8.19e-244	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
PAILFIKI_01753	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
PAILFIKI_01754	5.32e-142	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
PAILFIKI_01755	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
PAILFIKI_01756	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PAILFIKI_01757	2.11e-197	ypuA	-	-	S	-	-	-	Secreted protein
PAILFIKI_01758	4.12e-104	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PAILFIKI_01759	1.42e-107	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
PAILFIKI_01760	6.56e-131	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PAILFIKI_01761	4.92e-71	ypuD	-	-	-	-	-	-	-
PAILFIKI_01762	1.08e-267	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PAILFIKI_01763	3.97e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
PAILFIKI_01764	1.8e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PAILFIKI_01765	6.92e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PAILFIKI_01766	2.74e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAILFIKI_01767	4.51e-118	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
PAILFIKI_01769	2.09e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PAILFIKI_01770	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PAILFIKI_01771	6.14e-122	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
PAILFIKI_01772	1.62e-275	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PAILFIKI_01773	3.75e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
PAILFIKI_01774	8.99e-116	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
PAILFIKI_01775	1.49e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PAILFIKI_01776	4.31e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PAILFIKI_01777	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
PAILFIKI_01778	4.39e-252	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PAILFIKI_01779	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_01780	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_01781	3.22e-135	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PAILFIKI_01782	5.62e-254	rsiX	-	-	-	-	-	-	-
PAILFIKI_01783	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAILFIKI_01784	2.16e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PAILFIKI_01785	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
PAILFIKI_01786	7.41e-254	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
PAILFIKI_01787	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
PAILFIKI_01788	1.09e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
PAILFIKI_01789	1.5e-132	ypbE	-	-	M	-	-	-	Lysin motif
PAILFIKI_01790	1.92e-111	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
PAILFIKI_01791	1.15e-189	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
PAILFIKI_01792	3.35e-137	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PAILFIKI_01793	1.81e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
PAILFIKI_01794	1.85e-239	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
PAILFIKI_01795	7.48e-155	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
PAILFIKI_01796	1.92e-204	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
PAILFIKI_01797	4.92e-306	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
PAILFIKI_01798	3.83e-76	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
PAILFIKI_01799	7.86e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
PAILFIKI_01800	5.8e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PAILFIKI_01801	5.73e-264	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PAILFIKI_01802	1.98e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PAILFIKI_01803	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
PAILFIKI_01804	6.19e-136	yphA	-	-	-	-	-	-	-
PAILFIKI_01805	9.53e-317	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PAILFIKI_01806	4.93e-244	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PAILFIKI_01807	3.25e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
PAILFIKI_01808	3.4e-173	yphF	-	-	-	-	-	-	-
PAILFIKI_01809	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PAILFIKI_01810	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PAILFIKI_01811	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
PAILFIKI_01812	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PAILFIKI_01813	3.96e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PAILFIKI_01814	7.76e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PAILFIKI_01815	2.29e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PAILFIKI_01816	8.53e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PAILFIKI_01817	3.54e-181	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
PAILFIKI_01818	9.75e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PAILFIKI_01819	7.47e-259	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PAILFIKI_01820	2.93e-79	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PAILFIKI_01821	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PAILFIKI_01822	2.37e-211	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PAILFIKI_01823	2.46e-169	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
PAILFIKI_01824	2.05e-147	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
PAILFIKI_01825	1.42e-289	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PAILFIKI_01826	7.71e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PAILFIKI_01827	7.15e-256	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PAILFIKI_01828	1.24e-260	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
PAILFIKI_01829	3.46e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PAILFIKI_01830	1.76e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
PAILFIKI_01831	2.6e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
PAILFIKI_01832	3.34e-101	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
PAILFIKI_01833	2.86e-127	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
PAILFIKI_01834	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
PAILFIKI_01835	4.02e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
PAILFIKI_01836	7.24e-134	ypjA	-	-	S	-	-	-	membrane
PAILFIKI_01837	2.05e-182	ypjB	-	-	S	-	-	-	sporulation protein
PAILFIKI_01838	1.97e-55	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
PAILFIKI_01839	5.09e-212	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
PAILFIKI_01840	4.31e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PAILFIKI_01841	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
PAILFIKI_01842	3.98e-188	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PAILFIKI_01843	6.19e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
PAILFIKI_01844	7.44e-169	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
PAILFIKI_01845	2.98e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
PAILFIKI_01846	3.99e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PAILFIKI_01847	7.73e-231	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PAILFIKI_01848	1.14e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PAILFIKI_01849	1.99e-202	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PAILFIKI_01850	2.41e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PAILFIKI_01851	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PAILFIKI_01852	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
PAILFIKI_01853	2.27e-103	ypmB	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01854	1.46e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
PAILFIKI_01855	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
PAILFIKI_01856	3.42e-167	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
PAILFIKI_01857	1.02e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PAILFIKI_01858	1.04e-118	ypoC	-	-	-	-	-	-	-
PAILFIKI_01859	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PAILFIKI_01860	8.84e-146	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PAILFIKI_01861	4.72e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
PAILFIKI_01862	0.000542	-	-	-	-	ko:K06430	-	ko00000	-
PAILFIKI_01866	1.85e-74	yppG	-	-	S	-	-	-	YppG-like protein
PAILFIKI_01867	1.85e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PAILFIKI_01868	1.21e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
PAILFIKI_01869	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PAILFIKI_01870	1.99e-302	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
PAILFIKI_01872	9.36e-48	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
PAILFIKI_01873	1.33e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PAILFIKI_01874	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PAILFIKI_01875	5.46e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PAILFIKI_01876	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
PAILFIKI_01878	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
PAILFIKI_01879	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PAILFIKI_01880	4.72e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PAILFIKI_01881	2.22e-192	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
PAILFIKI_01882	1.57e-82	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
PAILFIKI_01883	1.05e-05	-	-	-	-	-	-	-	-
PAILFIKI_01884	3.79e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
PAILFIKI_01885	1.21e-08	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
PAILFIKI_01886	3.81e-67	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
PAILFIKI_01887	2.52e-136	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PAILFIKI_01888	5.13e-268	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
PAILFIKI_01889	2.09e-116	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
PAILFIKI_01890	0.0	ypbR	-	-	S	-	-	-	Dynamin family
PAILFIKI_01891	8.23e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
PAILFIKI_01892	2.44e-10	-	-	-	-	-	-	-	-
PAILFIKI_01893	3.33e-210	ypcP	-	-	L	-	-	-	5'3' exonuclease
PAILFIKI_01895	7.37e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
PAILFIKI_01896	2.79e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PAILFIKI_01897	2.06e-159	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
PAILFIKI_01898	6.59e-40	ypeQ	-	-	S	-	-	-	Zinc-finger
PAILFIKI_01899	9.27e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
PAILFIKI_01900	5.19e-17	degR	-	-	-	-	-	-	-
PAILFIKI_01901	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
PAILFIKI_01902	1.49e-274	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PAILFIKI_01903	2.3e-227	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PAILFIKI_01904	9.26e-112	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
PAILFIKI_01905	7.66e-127	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
PAILFIKI_01906	5.44e-202	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
PAILFIKI_01907	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
PAILFIKI_01908	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
PAILFIKI_01909	8.22e-171	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
PAILFIKI_01910	6.48e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
PAILFIKI_01911	6.22e-204	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PAILFIKI_01912	6.07e-117	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PAILFIKI_01913	1.35e-147	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PAILFIKI_01914	1.5e-142	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
PAILFIKI_01915	5.8e-224	yplP	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_01916	1.42e-307	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PAILFIKI_01917	8.98e-55	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
PAILFIKI_01918	2.43e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PAILFIKI_01919	6.09e-175	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PAILFIKI_01920	5.59e-126	ypmS	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01921	3.35e-89	ypoP	-	-	K	-	-	-	transcriptional
PAILFIKI_01922	2.82e-132	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PAILFIKI_01923	4.61e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PAILFIKI_01924	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_01925	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_01926	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_01927	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_01928	4.26e-59	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
PAILFIKI_01930	5.67e-205	-	-	-	S	-	-	-	amine dehydrogenase activity
PAILFIKI_01932	2.6e-66	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
PAILFIKI_01933	6.1e-296	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PAILFIKI_01934	4.26e-109	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
PAILFIKI_01935	4.29e-109	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
PAILFIKI_01936	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PAILFIKI_01937	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAILFIKI_01938	8.67e-40	yazB	-	-	K	-	-	-	transcriptional
PAILFIKI_01939	3.34e-117	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PAILFIKI_01940	1.13e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PAILFIKI_01941	2.24e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PAILFIKI_01942	2.83e-206	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
PAILFIKI_01943	2.97e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
PAILFIKI_01944	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PAILFIKI_01945	2.09e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PAILFIKI_01946	2.79e-198	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
PAILFIKI_01947	1.3e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PAILFIKI_01948	6.64e-187	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PAILFIKI_01949	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PAILFIKI_01950	1.05e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
PAILFIKI_01951	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PAILFIKI_01952	3.3e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PAILFIKI_01953	5.38e-166	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
PAILFIKI_01954	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
PAILFIKI_01955	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
PAILFIKI_01956	6.94e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PAILFIKI_01957	1.95e-133	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
PAILFIKI_01958	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
PAILFIKI_01959	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PAILFIKI_01960	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PAILFIKI_01961	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAILFIKI_01962	8.02e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
PAILFIKI_01963	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PAILFIKI_01964	1.1e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
PAILFIKI_01965	1.74e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PAILFIKI_01966	3.57e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PAILFIKI_01967	2.47e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PAILFIKI_01968	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PAILFIKI_01969	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PAILFIKI_01970	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
PAILFIKI_01971	5.67e-197	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PAILFIKI_01972	2.73e-206	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PAILFIKI_01973	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
PAILFIKI_01974	3.08e-52	veg	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01975	6.71e-208	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
PAILFIKI_01976	2.07e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PAILFIKI_01977	7.62e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PAILFIKI_01978	3.23e-306	yabE	-	-	T	-	-	-	protein conserved in bacteria
PAILFIKI_01979	1.02e-182	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
PAILFIKI_01980	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAILFIKI_01981	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
PAILFIKI_01982	1.65e-209	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PAILFIKI_01983	6.96e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
PAILFIKI_01984	3.99e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
PAILFIKI_01985	3.08e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PAILFIKI_01986	9e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
PAILFIKI_01987	4.41e-228	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PAILFIKI_01988	2.98e-94	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
PAILFIKI_01989	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_01990	1.9e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PAILFIKI_01991	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
PAILFIKI_01992	2.32e-242	yaaN	-	-	P	-	-	-	Belongs to the TelA family
PAILFIKI_01993	7.19e-137	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
PAILFIKI_01994	4.46e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
PAILFIKI_01995	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_01998	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PAILFIKI_01999	1.98e-133	-	-	-	S	-	-	-	AAA ATPase domain
PAILFIKI_02000	1.78e-175	-	-	-	M	-	-	-	PFAM Collagen triple helix repeat (20 copies)
PAILFIKI_02001	7.1e-275	-	-	-	M	-	-	-	Glycosyl transferase family 2
PAILFIKI_02003	1.49e-59	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PAILFIKI_02004	3.2e-91	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
PAILFIKI_02005	9.88e-111	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
PAILFIKI_02006	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
PAILFIKI_02007	7.94e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PAILFIKI_02008	1.77e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PAILFIKI_02009	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PAILFIKI_02010	4.97e-64	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
PAILFIKI_02011	2.37e-68	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
PAILFIKI_02012	7.43e-130	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PAILFIKI_02013	3.06e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
PAILFIKI_02014	3.44e-203	ykgA	-	-	E	-	-	-	Amidinotransferase
PAILFIKI_02015	3.43e-262	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
PAILFIKI_02016	6.62e-231	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_02017	2.55e-216	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PAILFIKI_02018	4.3e-255	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
PAILFIKI_02019	1.09e-223	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
PAILFIKI_02020	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PAILFIKI_02021	4.37e-241	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_02022	1.89e-226	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAILFIKI_02023	3.98e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAILFIKI_02024	4.36e-200	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
PAILFIKI_02025	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
PAILFIKI_02026	1.07e-275	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAILFIKI_02028	1.56e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
PAILFIKI_02029	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PAILFIKI_02030	4.3e-228	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
PAILFIKI_02031	2.64e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PAILFIKI_02032	1.2e-140	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
PAILFIKI_02033	1.22e-226	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
PAILFIKI_02034	1.89e-172	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
PAILFIKI_02035	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
PAILFIKI_02036	2.02e-214	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
PAILFIKI_02037	4.7e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
PAILFIKI_02038	3.87e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
PAILFIKI_02039	3.67e-177	xepA	-	-	-	-	-	-	-
PAILFIKI_02040	1.32e-39	xkdX	-	-	-	-	-	-	-
PAILFIKI_02042	4.87e-109	-	-	-	-	-	-	-	-
PAILFIKI_02043	8.92e-38	-	-	-	-	-	-	-	-
PAILFIKI_02044	4.1e-112	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
PAILFIKI_02045	4.38e-212	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PAILFIKI_02046	4.74e-75	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
PAILFIKI_02047	2.51e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
PAILFIKI_02048	2.66e-206	xkdQ	-	-	G	-	-	-	NLP P60 protein
PAILFIKI_02049	6.56e-145	xkdP	-	-	S	-	-	-	Lysin motif
PAILFIKI_02050	4.36e-252	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
PAILFIKI_02051	4.33e-27	-	-	-	-	-	-	-	-
PAILFIKI_02052	2.09e-95	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
PAILFIKI_02053	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
PAILFIKI_02054	2.31e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
PAILFIKI_02055	1.45e-20	-	-	-	-	-	-	-	-
PAILFIKI_02056	1.05e-74	xkdJ	-	-	-	-	-	-	-
PAILFIKI_02057	8.03e-76	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
PAILFIKI_02058	1.42e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
PAILFIKI_02059	3.6e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
PAILFIKI_02060	8.3e-203	xkdG	-	-	S	-	-	-	Phage capsid family
PAILFIKI_02061	8.8e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
PAILFIKI_02062	5.17e-304	xkdE3	-	-	S	-	-	-	portal protein
PAILFIKI_02063	1.36e-262	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
PAILFIKI_02064	1.24e-142	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
PAILFIKI_02065	3.05e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PAILFIKI_02069	2.94e-194	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
PAILFIKI_02071	6.52e-75	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PAILFIKI_02072	6.51e-145	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
PAILFIKI_02073	2.63e-142	yjqB	-	-	S	-	-	-	phage-related replication protein
PAILFIKI_02074	9.51e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
PAILFIKI_02075	1.94e-220	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
PAILFIKI_02077	2.68e-275	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
PAILFIKI_02078	8.38e-103	yjoA	-	-	S	-	-	-	DinB family
PAILFIKI_02079	3.21e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PAILFIKI_02080	3.25e-243	lcnDR2	-	-	V	-	-	-	Domain of unknown function (DUF4135)
PAILFIKI_02083	2.77e-276	lanT	-	-	V	ko:K06148,ko:K13409,ko:K20344,ko:K20386	ko02010,ko02024,ko04626,map02010,map02024,map04626	ko00000,ko00001,ko00002,ko02000,ko02044	Peptidase C39 family
PAILFIKI_02084	0.0	lcnDR2	-	-	V	-	-	-	Lanthionine synthetase C-like protein
PAILFIKI_02086	1.26e-75	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAILFIKI_02087	4.67e-50	-	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_02089	7.74e-86	-	-	-	S	-	-	-	ABC-2 family transporter protein
PAILFIKI_02090	1.11e-132	-	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_02091	4.91e-167	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PAILFIKI_02092	1.83e-112	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PAILFIKI_02093	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
PAILFIKI_02094	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
PAILFIKI_02095	1.24e-235	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
PAILFIKI_02096	0.0	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
PAILFIKI_02097	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
PAILFIKI_02098	1.76e-279	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PAILFIKI_02099	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
PAILFIKI_02100	4.96e-118	yjlB	-	-	S	-	-	-	Cupin domain
PAILFIKI_02101	2.38e-226	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
PAILFIKI_02102	3.08e-166	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_02103	3.6e-158	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
PAILFIKI_02104	4.13e-188	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
PAILFIKI_02105	1.73e-40	-	-	-	-	-	-	-	-
PAILFIKI_02106	1.64e-283	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PAILFIKI_02107	3.25e-291	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
PAILFIKI_02108	2.2e-117	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
PAILFIKI_02109	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
PAILFIKI_02110	3.92e-129	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
PAILFIKI_02111	1.48e-90	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
PAILFIKI_02112	1.91e-31	yjfB	-	-	S	-	-	-	Putative motility protein
PAILFIKI_02114	2.89e-135	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
PAILFIKI_02115	1.19e-68	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PAILFIKI_02116	1.69e-46	-	-	-	-	-	-	-	-
PAILFIKI_02117	1.62e-158	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PAILFIKI_02118	1.62e-176	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
PAILFIKI_02119	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PAILFIKI_02120	8.91e-67	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_02121	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAILFIKI_02122	4.28e-274	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PAILFIKI_02123	2.09e-242	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PAILFIKI_02124	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PAILFIKI_02125	1.34e-281	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
PAILFIKI_02126	1.06e-106	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PAILFIKI_02127	0.0	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
PAILFIKI_02128	3.12e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
PAILFIKI_02129	1.64e-210	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
PAILFIKI_02130	3.27e-78	-	-	-	E	-	-	-	Glyoxalase-like domain
PAILFIKI_02134	5.45e-121	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
PAILFIKI_02136	9.34e-51	-	-	-	-	-	-	-	-
PAILFIKI_02137	1.42e-29	-	-	-	-	-	-	-	-
PAILFIKI_02138	1.14e-26	-	-	-	-	-	-	-	-
PAILFIKI_02140	1.37e-271	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PAILFIKI_02141	3.93e-271	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PAILFIKI_02142	1.23e-164	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
PAILFIKI_02143	6.97e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
PAILFIKI_02144	2.48e-96	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAILFIKI_02145	4.32e-48	-	-	-	K	-	-	-	SpoVT / AbrB like domain
PAILFIKI_02146	3.53e-171	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PAILFIKI_02147	4.59e-160	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PAILFIKI_02148	2.06e-181	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
PAILFIKI_02149	2.48e-48	-	-	-	-	-	-	-	-
PAILFIKI_02150	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PAILFIKI_02151	2.57e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
PAILFIKI_02152	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
PAILFIKI_02155	8.37e-73	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
PAILFIKI_02156	9.7e-71	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
PAILFIKI_02157	4.1e-43	cotW	-	-	-	ko:K06341	-	ko00000	-
PAILFIKI_02158	1.51e-99	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
PAILFIKI_02159	2.48e-120	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
PAILFIKI_02160	2.1e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
PAILFIKI_02161	7.96e-124	yjbX	-	-	S	-	-	-	Spore coat protein
PAILFIKI_02162	6.85e-180	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
PAILFIKI_02163	4.3e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PAILFIKI_02164	1.52e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PAILFIKI_02165	1.81e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PAILFIKI_02166	5.5e-42	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
PAILFIKI_02167	4.57e-268	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
PAILFIKI_02168	6.36e-138	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
PAILFIKI_02169	8.38e-135	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PAILFIKI_02170	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PAILFIKI_02171	3.05e-183	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PAILFIKI_02172	2.35e-211	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PAILFIKI_02173	2.07e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PAILFIKI_02174	1.56e-139	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
PAILFIKI_02175	4.78e-79	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
PAILFIKI_02176	1.72e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_02177	3.12e-152	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PAILFIKI_02178	2.03e-92	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
PAILFIKI_02179	1.22e-219	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
PAILFIKI_02180	1.06e-25	-	-	-	-	-	-	-	-
PAILFIKI_02181	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PAILFIKI_02182	9.45e-281	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PAILFIKI_02183	9.78e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PAILFIKI_02184	4.59e-140	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
PAILFIKI_02185	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PAILFIKI_02186	2.55e-131	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAILFIKI_02187	3.5e-295	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
PAILFIKI_02188	1.42e-216	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_02189	1.5e-256	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_02190	6.93e-208	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAILFIKI_02191	1.46e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAILFIKI_02192	1.48e-92	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PAILFIKI_02193	2.33e-264	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PAILFIKI_02194	4.85e-232	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
PAILFIKI_02195	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
PAILFIKI_02196	1.67e-198	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAILFIKI_02197	5.76e-217	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAILFIKI_02198	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
PAILFIKI_02199	7.23e-238	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_02200	8.37e-232	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_02201	7.48e-190	yjaZ	-	-	O	-	-	-	Zn-dependent protease
PAILFIKI_02202	9.08e-299	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PAILFIKI_02203	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAILFIKI_02204	2.72e-42	yjzB	-	-	-	-	-	-	-
PAILFIKI_02205	6.46e-37	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
PAILFIKI_02206	4.67e-213	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
PAILFIKI_02207	1.67e-134	yjaV	-	-	-	-	-	-	-
PAILFIKI_02208	3.04e-176	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
PAILFIKI_02209	1.24e-31	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PAILFIKI_02210	7.21e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
PAILFIKI_02211	8.28e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PAILFIKI_02212	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
PAILFIKI_02213	2.31e-257	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PAILFIKI_02214	3.98e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
PAILFIKI_02215	5.17e-175	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
PAILFIKI_02216	2.99e-289	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PAILFIKI_02217	5.84e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PAILFIKI_02218	1.18e-121	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
PAILFIKI_02219	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
PAILFIKI_02220	1.12e-103	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PAILFIKI_02221	1.33e-67	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
PAILFIKI_02222	8.73e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
PAILFIKI_02223	5.08e-197	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PAILFIKI_02224	1.49e-11	-	-	-	-	-	-	-	-
PAILFIKI_02225	1.5e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
PAILFIKI_02226	6.41e-106	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
PAILFIKI_02227	4.62e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PAILFIKI_02228	2.68e-184	yitS	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_02230	1.79e-307	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
PAILFIKI_02231	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PAILFIKI_02232	8.51e-219	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
PAILFIKI_02233	7.54e-205	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
PAILFIKI_02234	3.69e-78	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
PAILFIKI_02235	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PAILFIKI_02236	1.8e-104	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PAILFIKI_02237	1.6e-103	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
PAILFIKI_02238	5.57e-238	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAILFIKI_02239	1.71e-95	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
PAILFIKI_02240	1.48e-114	yisT	-	-	S	-	-	-	DinB family
PAILFIKI_02241	4.31e-31	-	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
PAILFIKI_02242	4.72e-206	yisR	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_02243	6.12e-312	yisQ	-	-	V	-	-	-	Mate efflux family protein
PAILFIKI_02244	1.81e-169	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
PAILFIKI_02245	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PAILFIKI_02246	2.17e-123	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
PAILFIKI_02247	2.22e-78	yisL	-	-	S	-	-	-	UPF0344 protein
PAILFIKI_02248	1.54e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PAILFIKI_02249	1.59e-11	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
PAILFIKI_02250	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
PAILFIKI_02251	6.59e-48	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
PAILFIKI_02252	8.51e-109	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
PAILFIKI_02253	3e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
PAILFIKI_02254	1.09e-82	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
PAILFIKI_02255	6.66e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
PAILFIKI_02256	6.24e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
PAILFIKI_02257	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
PAILFIKI_02258	4.7e-283	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PAILFIKI_02259	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PAILFIKI_02260	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
PAILFIKI_02261	5.11e-153	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
PAILFIKI_02262	3.6e-122	yhjR	-	-	S	-	-	-	Rubrerythrin
PAILFIKI_02263	1.06e-139	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
PAILFIKI_02264	1.78e-266	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_02265	9.85e-262	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
PAILFIKI_02266	4.89e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PAILFIKI_02267	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
PAILFIKI_02268	3.32e-119	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PAILFIKI_02269	2.23e-142	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
PAILFIKI_02270	4.12e-79	yhjD	-	-	-	-	-	-	-
PAILFIKI_02271	5.59e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
PAILFIKI_02272	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAILFIKI_02273	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
PAILFIKI_02274	1.23e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
PAILFIKI_02275	1.49e-161	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
PAILFIKI_02276	4.93e-82	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
PAILFIKI_02277	2.09e-87	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
PAILFIKI_02278	1.09e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
PAILFIKI_02279	3.87e-42	yhzC	-	-	S	-	-	-	IDEAL
PAILFIKI_02280	3.88e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAILFIKI_02281	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
PAILFIKI_02282	1.87e-275	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
PAILFIKI_02283	7.56e-116	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
PAILFIKI_02284	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
PAILFIKI_02285	2.38e-251	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PAILFIKI_02286	6.03e-134	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
PAILFIKI_02287	7.33e-192	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PAILFIKI_02288	1.57e-261	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PAILFIKI_02289	3.56e-298	yhfN	-	-	O	-	-	-	Peptidase M48
PAILFIKI_02290	7.96e-85	yhfM	-	-	-	-	-	-	-
PAILFIKI_02291	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
PAILFIKI_02292	1.05e-141	yhfK	-	-	GM	-	-	-	NmrA-like family
PAILFIKI_02293	6.47e-242	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
PAILFIKI_02294	4.01e-181	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PAILFIKI_02296	3.43e-282	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAILFIKI_02297	2.11e-250	yhfE	-	-	G	-	-	-	peptidase M42
PAILFIKI_02299	5.92e-235	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAILFIKI_02300	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
PAILFIKI_02301	4.41e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_02302	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PAILFIKI_02303	4.49e-232	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
PAILFIKI_02304	8.58e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PAILFIKI_02305	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PAILFIKI_02306	3.1e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
PAILFIKI_02307	3.98e-311	yhfA	-	-	C	-	-	-	membrane
PAILFIKI_02308	1.53e-286	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PAILFIKI_02309	1.75e-161	ecsC	-	-	S	-	-	-	EcsC protein family
PAILFIKI_02310	6.41e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PAILFIKI_02311	3.02e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
PAILFIKI_02312	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PAILFIKI_02313	5.91e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PAILFIKI_02314	1.43e-100	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
PAILFIKI_02315	2.55e-24	-	-	-	-	-	-	-	-
PAILFIKI_02316	4.74e-55	yhaH	-	-	S	-	-	-	YtxH-like protein
PAILFIKI_02317	4.73e-146	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
PAILFIKI_02318	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
PAILFIKI_02319	1.29e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
PAILFIKI_02320	1.36e-183	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PAILFIKI_02321	4.95e-44	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
PAILFIKI_02322	2.48e-226	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
PAILFIKI_02323	0.0	yhaN	-	-	L	-	-	-	AAA domain
PAILFIKI_02324	7.47e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
PAILFIKI_02325	4.82e-277	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
PAILFIKI_02326	3.92e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_02327	5.99e-21	-	-	-	S	-	-	-	YhzD-like protein
PAILFIKI_02328	1.18e-174	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
PAILFIKI_02330	3.62e-111	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
PAILFIKI_02331	1.41e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
PAILFIKI_02332	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
PAILFIKI_02333	2.95e-205	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PAILFIKI_02334	1.74e-258	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
PAILFIKI_02335	2.32e-70	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PAILFIKI_02336	7.84e-264	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
PAILFIKI_02337	1.54e-272	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
PAILFIKI_02338	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
PAILFIKI_02339	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
PAILFIKI_02340	3.3e-39	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
PAILFIKI_02342	7.8e-142	yheG	-	-	GM	-	-	-	NAD(P)H-binding
PAILFIKI_02343	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
PAILFIKI_02344	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
PAILFIKI_02346	2.49e-110	-	-	-	T	-	-	-	universal stress protein
PAILFIKI_02347	3.12e-123	ymcC	-	-	S	-	-	-	Membrane
PAILFIKI_02348	1.43e-113	pksA	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_02349	3.99e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PAILFIKI_02350	4.01e-200	nodB1	-	-	G	-	-	-	deacetylase
PAILFIKI_02351	7.18e-181	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PAILFIKI_02352	4.51e-260	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
PAILFIKI_02353	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
PAILFIKI_02354	1.49e-164	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PAILFIKI_02355	4.97e-79	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAILFIKI_02356	2.9e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAILFIKI_02357	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
PAILFIKI_02358	9.1e-300	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PAILFIKI_02359	4.05e-286	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
PAILFIKI_02360	1.19e-93	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
PAILFIKI_02361	2.28e-306	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
PAILFIKI_02362	9.21e-142	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PAILFIKI_02363	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PAILFIKI_02364	6.88e-257	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
PAILFIKI_02365	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
PAILFIKI_02366	8.02e-265	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PAILFIKI_02367	1.78e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
PAILFIKI_02368	1.58e-205	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAILFIKI_02369	6.39e-259	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
PAILFIKI_02370	8.17e-209	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_02371	2.8e-171	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
PAILFIKI_02372	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
PAILFIKI_02373	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
PAILFIKI_02374	1e-308	ygxB	-	-	M	-	-	-	Conserved TM helix
PAILFIKI_02375	3.79e-96	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
PAILFIKI_02376	8.6e-66	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
PAILFIKI_02377	2.67e-184	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
PAILFIKI_02378	2.94e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
PAILFIKI_02379	1.16e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
PAILFIKI_02380	9.77e-116	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
PAILFIKI_02381	1.56e-143	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAILFIKI_02382	8.75e-262	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_02383	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
PAILFIKI_02384	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PAILFIKI_02385	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PAILFIKI_02386	2.83e-199	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PAILFIKI_02387	5.16e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PAILFIKI_02388	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAILFIKI_02389	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PAILFIKI_02390	3.41e-161	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
PAILFIKI_02391	6.12e-91	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
PAILFIKI_02392	7.37e-90	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
PAILFIKI_02393	2.27e-216	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PAILFIKI_02394	1.3e-136	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
PAILFIKI_02395	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PAILFIKI_02396	4.45e-151	yhcQ	-	-	M	-	-	-	Spore coat protein
PAILFIKI_02397	1.85e-204	yhcP	-	-	-	-	-	-	-
PAILFIKI_02398	2.69e-122	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PAILFIKI_02399	4.31e-292	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAILFIKI_02400	1.1e-222	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
PAILFIKI_02401	5.86e-190	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PAILFIKI_02402	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
PAILFIKI_02403	2.23e-209	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PAILFIKI_02404	1.6e-89	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_02405	1.41e-72	yhcC	-	-	-	-	-	-	-
PAILFIKI_02406	9.09e-129	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PAILFIKI_02407	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
PAILFIKI_02408	1.54e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
PAILFIKI_02409	4.15e-98	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
PAILFIKI_02410	5.45e-279	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
PAILFIKI_02411	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
PAILFIKI_02412	1.23e-07	-	-	-	-	-	-	-	-
PAILFIKI_02413	2.02e-94	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
PAILFIKI_02414	3.99e-85	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
PAILFIKI_02415	4.63e-139	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
PAILFIKI_02416	4.84e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PAILFIKI_02417	2.08e-225	yhbB	-	-	S	-	-	-	Putative amidase domain
PAILFIKI_02418	2.08e-287	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PAILFIKI_02419	7.82e-147	yhzB	-	-	S	-	-	-	B3/4 domain
PAILFIKI_02420	9.41e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_02421	1.29e-106	ygaO	-	-	-	-	-	-	-
PAILFIKI_02422	3.39e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PAILFIKI_02423	1.17e-270	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
PAILFIKI_02424	8.27e-186	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
PAILFIKI_02425	7.12e-229	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
PAILFIKI_02426	1.5e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PAILFIKI_02427	4.68e-234	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
PAILFIKI_02428	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
PAILFIKI_02429	8.35e-154	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_02430	3.14e-169	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PAILFIKI_02431	8.8e-162	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAILFIKI_02432	1.17e-178	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PAILFIKI_02433	9.91e-288	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
PAILFIKI_02435	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
PAILFIKI_02436	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PAILFIKI_02437	1.57e-172	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
PAILFIKI_02438	4.79e-259	-	-	-	C	-	-	-	Na+/H+ antiporter family
PAILFIKI_02443	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_02444	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
PAILFIKI_02445	1.96e-84	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
PAILFIKI_02446	2.89e-236	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
PAILFIKI_02447	1.79e-266	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
PAILFIKI_02448	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PAILFIKI_02449	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
PAILFIKI_02450	2.77e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
PAILFIKI_02451	3.48e-214	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
PAILFIKI_02452	1.67e-176	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
PAILFIKI_02453	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PAILFIKI_02454	5.33e-135	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
PAILFIKI_02455	3.16e-144	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PAILFIKI_02456	2.26e-95	yngA	-	-	S	-	-	-	membrane
PAILFIKI_02457	8.7e-184	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PAILFIKI_02458	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PAILFIKI_02459	3.25e-272	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PAILFIKI_02460	7.45e-167	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PAILFIKI_02461	1.12e-246	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PAILFIKI_02462	3.74e-284	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
PAILFIKI_02463	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
PAILFIKI_02464	8.91e-162	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PAILFIKI_02465	7.47e-156	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PAILFIKI_02466	1.18e-177	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PAILFIKI_02467	7.87e-270	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
PAILFIKI_02468	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_02469	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_02470	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAILFIKI_02471	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
PAILFIKI_02472	8.84e-316	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
PAILFIKI_02473	6.28e-163	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PAILFIKI_02474	5.65e-311	-	-	-	T	-	-	-	Histidine kinase
PAILFIKI_02475	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
PAILFIKI_02476	1.44e-270	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
PAILFIKI_02478	4.6e-13	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
PAILFIKI_02479	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
PAILFIKI_02480	4.51e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
PAILFIKI_02481	2e-199	yndG	-	-	S	-	-	-	DoxX-like family
PAILFIKI_02482	1.07e-284	exuT	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	Sugar (and other) transporter
PAILFIKI_02483	2.14e-232	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
PAILFIKI_02484	5.86e-191	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PAILFIKI_02485	3.96e-271	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
PAILFIKI_02486	5.27e-147	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
PAILFIKI_02487	1.26e-243	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
PAILFIKI_02488	1.15e-233	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
PAILFIKI_02489	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
PAILFIKI_02490	1.82e-63	ynfC	-	-	-	-	-	-	-
PAILFIKI_02491	5.42e-20	-	-	-	-	-	-	-	-
PAILFIKI_02492	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PAILFIKI_02493	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PAILFIKI_02494	9.94e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
PAILFIKI_02495	2.6e-120	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PAILFIKI_02496	2.67e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
PAILFIKI_02497	7.79e-70	yneQ	-	-	-	-	-	-	-
PAILFIKI_02498	2.94e-97	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
PAILFIKI_02499	1.73e-44	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
PAILFIKI_02501	8.17e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PAILFIKI_02502	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PAILFIKI_02503	1.47e-20	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
PAILFIKI_02504	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
PAILFIKI_02505	7.01e-82	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
PAILFIKI_02506	1.18e-98	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
PAILFIKI_02507	2.27e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
PAILFIKI_02508	7.09e-76	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
PAILFIKI_02509	3.14e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
PAILFIKI_02510	1.97e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
PAILFIKI_02511	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
PAILFIKI_02512	1.08e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
PAILFIKI_02513	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PAILFIKI_02514	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
PAILFIKI_02515	5.22e-145	yneB	-	-	L	-	-	-	resolvase
PAILFIKI_02516	1.01e-67	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PAILFIKI_02517	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PAILFIKI_02519	3.2e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
PAILFIKI_02520	1.04e-183	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
PAILFIKI_02521	1.74e-11	-	-	-	-	-	-	-	-
PAILFIKI_02522	1.37e-182	yndL	-	-	S	-	-	-	Replication protein
PAILFIKI_02523	6.07e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
PAILFIKI_02524	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
PAILFIKI_02526	3.23e-47	yvgO	-	-	-	-	-	-	-
PAILFIKI_02528	9.28e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
PAILFIKI_02529	3.33e-152	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
PAILFIKI_02530	6.88e-257	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAILFIKI_02531	4.55e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
PAILFIKI_02532	3.28e-128	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PAILFIKI_02533	1.64e-77	yoaP	-	-	K	-	-	-	YoaP-like
PAILFIKI_02534	1.34e-94	yoaP	-	-	K	-	-	-	YoaP-like
PAILFIKI_02536	2.75e-39	-	-	-	-	-	-	-	-
PAILFIKI_02538	2.78e-24	-	-	-	-	-	-	-	-
PAILFIKI_02539	3.63e-96	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
PAILFIKI_02540	8.07e-235	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PAILFIKI_02541	8.43e-73	dinB	-	-	S	-	-	-	DinB family
PAILFIKI_02542	2.21e-27	-	-	-	-	-	-	-	-
PAILFIKI_02546	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
PAILFIKI_02547	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
PAILFIKI_02548	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
PAILFIKI_02549	9.04e-278	xylR	-	-	GK	-	-	-	ROK family
PAILFIKI_02550	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
PAILFIKI_02551	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
PAILFIKI_02552	3.19e-265	mrjp	-	-	G	-	-	-	Major royal jelly protein
PAILFIKI_02553	4.7e-51	-	-	-	T	-	-	-	Histidine kinase
PAILFIKI_02554	2.1e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
PAILFIKI_02558	4.5e-115	-	-	-	-	-	-	-	-
PAILFIKI_02559	1.03e-28	-	-	-	-	-	-	-	-
PAILFIKI_02560	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PAILFIKI_02561	4.39e-88	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
PAILFIKI_02562	1.01e-311	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PAILFIKI_02563	2.7e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PAILFIKI_02564	1.55e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
PAILFIKI_02565	1.86e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
PAILFIKI_02566	2.24e-141	ymaB	-	-	S	-	-	-	MutT family
PAILFIKI_02567	5.77e-244	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAILFIKI_02568	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAILFIKI_02569	1.61e-88	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
PAILFIKI_02570	9.42e-29	ymzA	-	-	-	-	-	-	-
PAILFIKI_02571	2.86e-57	-	-	-	-	-	-	-	-
PAILFIKI_02572	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PAILFIKI_02573	7.32e-219	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PAILFIKI_02574	5.96e-77	ymaF	-	-	S	-	-	-	YmaF family
PAILFIKI_02576	1.82e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
PAILFIKI_02577	5.05e-70	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
PAILFIKI_02578	1.11e-100	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
PAILFIKI_02579	5.4e-161	ymaC	-	-	S	-	-	-	Replication protein
PAILFIKI_02580	4.29e-06	-	-	-	-	-	-	-	-
PAILFIKI_02581	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
PAILFIKI_02582	2.78e-82	ymzB	-	-	-	-	-	-	-
PAILFIKI_02583	4.46e-153	yoaK	-	-	S	-	-	-	Membrane
PAILFIKI_02584	4.27e-102	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
PAILFIKI_02585	6.55e-292	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
PAILFIKI_02586	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
PAILFIKI_02587	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
PAILFIKI_02588	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_02589	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_02590	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
PAILFIKI_02591	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
PAILFIKI_02592	3.42e-180	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
PAILFIKI_02593	5.05e-186	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
PAILFIKI_02594	3.63e-309	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
PAILFIKI_02595	5.27e-49	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
PAILFIKI_02596	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
PAILFIKI_02597	3.7e-233	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
PAILFIKI_02598	1.35e-206	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
PAILFIKI_02599	1.16e-165	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
PAILFIKI_02601	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PAILFIKI_02602	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PAILFIKI_02603	7.09e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
PAILFIKI_02604	2.11e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
PAILFIKI_02605	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PAILFIKI_02606	7.11e-274	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PAILFIKI_02607	8.3e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PAILFIKI_02608	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
PAILFIKI_02609	3.72e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
PAILFIKI_02610	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PAILFIKI_02611	5.01e-275	pbpX	-	-	V	-	-	-	Beta-lactamase
PAILFIKI_02612	3.06e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PAILFIKI_02613	4.64e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
PAILFIKI_02614	9.58e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PAILFIKI_02615	5.76e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
PAILFIKI_02616	3.14e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
PAILFIKI_02617	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
PAILFIKI_02618	2.88e-164	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PAILFIKI_02619	8.28e-310	ymfH	-	-	S	-	-	-	zinc protease
PAILFIKI_02620	1.12e-306	albE	-	-	S	-	-	-	Peptidase M16
PAILFIKI_02621	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
PAILFIKI_02622	9.88e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PAILFIKI_02623	3.16e-296	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_02624	4.48e-172	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_02625	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PAILFIKI_02626	6.32e-42	-	-	-	S	-	-	-	YlzJ-like protein
PAILFIKI_02627	2.27e-166	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
PAILFIKI_02628	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAILFIKI_02629	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PAILFIKI_02630	2e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PAILFIKI_02631	1.74e-249	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PAILFIKI_02632	1.36e-137	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PAILFIKI_02633	4.51e-204	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
PAILFIKI_02634	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
PAILFIKI_02635	5.91e-299	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
PAILFIKI_02636	4.15e-232	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
PAILFIKI_02637	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PAILFIKI_02638	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PAILFIKI_02639	2.6e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PAILFIKI_02640	1.73e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PAILFIKI_02641	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PAILFIKI_02642	3.88e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
PAILFIKI_02643	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PAILFIKI_02644	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
PAILFIKI_02645	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
PAILFIKI_02646	4.04e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PAILFIKI_02647	1.9e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PAILFIKI_02648	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAILFIKI_02649	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PAILFIKI_02650	1.15e-296	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PAILFIKI_02651	2.57e-272	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PAILFIKI_02652	3.8e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PAILFIKI_02653	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PAILFIKI_02654	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PAILFIKI_02655	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PAILFIKI_02656	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PAILFIKI_02657	7.07e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PAILFIKI_02658	5.85e-94	ylxL	-	-	-	-	-	-	-
PAILFIKI_02659	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAILFIKI_02660	2.86e-113	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PAILFIKI_02661	3.42e-142	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PAILFIKI_02662	2.49e-105	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
PAILFIKI_02663	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
PAILFIKI_02664	1.42e-248	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PAILFIKI_02665	6.35e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
PAILFIKI_02666	7.94e-250	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
PAILFIKI_02667	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PAILFIKI_02668	2.53e-242	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PAILFIKI_02669	5.74e-168	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
PAILFIKI_02670	3.15e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
PAILFIKI_02671	1.48e-142	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
PAILFIKI_02672	9.34e-144	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
PAILFIKI_02673	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
PAILFIKI_02674	8.47e-245	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PAILFIKI_02675	5.43e-230	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PAILFIKI_02676	1.81e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
PAILFIKI_02677	2.79e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
PAILFIKI_02678	8.9e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
PAILFIKI_02679	3e-260	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
PAILFIKI_02680	1.98e-88	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
PAILFIKI_02681	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
PAILFIKI_02682	5.19e-309	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PAILFIKI_02683	1.96e-122	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
PAILFIKI_02684	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PAILFIKI_02685	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
PAILFIKI_02686	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
PAILFIKI_02687	8.81e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
PAILFIKI_02688	2.8e-84	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PAILFIKI_02689	2.77e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PAILFIKI_02690	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PAILFIKI_02691	7.38e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PAILFIKI_02692	6.29e-220	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
PAILFIKI_02693	3.83e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PAILFIKI_02694	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PAILFIKI_02695	7.32e-216	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
PAILFIKI_02696	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PAILFIKI_02697	2.02e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PAILFIKI_02698	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
PAILFIKI_02699	0.0	ylqG	-	-	-	-	-	-	-
PAILFIKI_02700	3.37e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PAILFIKI_02701	5.09e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PAILFIKI_02702	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PAILFIKI_02703	5.67e-176	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PAILFIKI_02704	1.51e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PAILFIKI_02705	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
PAILFIKI_02706	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PAILFIKI_02707	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PAILFIKI_02708	1.47e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PAILFIKI_02709	8.01e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PAILFIKI_02710	1.57e-184	-	-	-	S	-	-	-	Phosphotransferase enzyme family
PAILFIKI_02711	1.87e-224	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PAILFIKI_02712	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PAILFIKI_02713	1.23e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PAILFIKI_02714	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAILFIKI_02715	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PAILFIKI_02716	3.76e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
PAILFIKI_02717	3.14e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PAILFIKI_02718	4.38e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PAILFIKI_02719	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PAILFIKI_02720	9.75e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
PAILFIKI_02721	4.15e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
PAILFIKI_02722	4.45e-80	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
PAILFIKI_02723	6.94e-288	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
PAILFIKI_02724	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_02725	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PAILFIKI_02726	4.34e-152	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PAILFIKI_02727	3.42e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PAILFIKI_02728	6.22e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PAILFIKI_02729	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PAILFIKI_02730	2.03e-177	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PAILFIKI_02731	1.52e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PAILFIKI_02732	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PAILFIKI_02733	2.64e-221	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PAILFIKI_02734	2.89e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PAILFIKI_02735	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PAILFIKI_02736	2.09e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PAILFIKI_02737	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PAILFIKI_02738	4.91e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PAILFIKI_02739	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
PAILFIKI_02740	2.14e-198	yloC	-	-	S	-	-	-	stress-induced protein
PAILFIKI_02741	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
PAILFIKI_02742	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
PAILFIKI_02743	6.27e-106	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
PAILFIKI_02744	4.15e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
PAILFIKI_02745	5.9e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
PAILFIKI_02746	6.76e-143	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
PAILFIKI_02747	1.77e-283	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
PAILFIKI_02748	1.21e-228	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
PAILFIKI_02749	9.88e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
PAILFIKI_02751	8.96e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PAILFIKI_02752	3.66e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PAILFIKI_02753	7.36e-222	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PAILFIKI_02754	1.18e-179	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PAILFIKI_02755	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
PAILFIKI_02756	8.86e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PAILFIKI_02757	1.55e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PAILFIKI_02758	1.47e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PAILFIKI_02759	2.81e-296	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
PAILFIKI_02760	8.98e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PAILFIKI_02761	5.35e-216	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PAILFIKI_02762	1.02e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PAILFIKI_02763	4.75e-80	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
PAILFIKI_02764	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PAILFIKI_02765	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
PAILFIKI_02766	6.12e-182	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
PAILFIKI_02767	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
PAILFIKI_02768	4.61e-85	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PAILFIKI_02769	3.68e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PAILFIKI_02770	9.55e-206	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
PAILFIKI_02771	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
PAILFIKI_02772	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
PAILFIKI_02773	8.04e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PAILFIKI_02774	9.33e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAILFIKI_02775	7.35e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAILFIKI_02776	8.23e-218	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PAILFIKI_02777	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
PAILFIKI_02778	2.61e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PAILFIKI_02779	1.57e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PAILFIKI_02780	2.67e-179	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PAILFIKI_02781	7.87e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
PAILFIKI_02782	3.29e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PAILFIKI_02783	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PAILFIKI_02784	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PAILFIKI_02785	7.04e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PAILFIKI_02786	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PAILFIKI_02787	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
PAILFIKI_02788	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PAILFIKI_02789	2.4e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
PAILFIKI_02790	8.23e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PAILFIKI_02791	1.03e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PAILFIKI_02792	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PAILFIKI_02793	2.85e-210	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAILFIKI_02794	1.14e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
PAILFIKI_02795	1.27e-110	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PAILFIKI_02796	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PAILFIKI_02797	3.3e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
PAILFIKI_02798	5.23e-295	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PAILFIKI_02799	8.8e-240	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PAILFIKI_02800	2.48e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
PAILFIKI_02801	9.73e-276	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
PAILFIKI_02802	8.3e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PAILFIKI_02803	7.68e-116	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
PAILFIKI_02804	3.94e-57	ylbG	-	-	S	-	-	-	UPF0298 protein
PAILFIKI_02805	2.74e-96	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
PAILFIKI_02806	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
PAILFIKI_02807	1.03e-87	ylbD	-	-	S	-	-	-	Putative coat protein
PAILFIKI_02808	3.97e-255	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
PAILFIKI_02809	9.59e-96	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
PAILFIKI_02810	4.12e-79	ylbA	-	-	S	-	-	-	YugN-like family
PAILFIKI_02811	8.46e-211	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
PAILFIKI_02812	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PAILFIKI_02813	5.92e-142	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PAILFIKI_02814	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PAILFIKI_02815	3.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PAILFIKI_02816	2.07e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PAILFIKI_02817	3.47e-214	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PAILFIKI_02818	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PAILFIKI_02819	8.59e-272	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PAILFIKI_02820	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
PAILFIKI_02821	5.18e-221	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PAILFIKI_02822	1.75e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PAILFIKI_02823	2.7e-313	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
PAILFIKI_02824	5.45e-138	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PAILFIKI_02825	6.78e-46	ylaI	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_02826	2.44e-65	-	-	-	S	-	-	-	YlaH-like protein
PAILFIKI_02827	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PAILFIKI_02828	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
PAILFIKI_02829	2.83e-62	ylaE	-	-	-	-	-	-	-
PAILFIKI_02831	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
PAILFIKI_02832	1.07e-107	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
PAILFIKI_02833	7.8e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
PAILFIKI_02834	3.33e-33	ykzI	-	-	-	-	-	-	-
PAILFIKI_02835	8.15e-155	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
PAILFIKI_02836	3.83e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
PAILFIKI_02837	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
PAILFIKI_02838	8.08e-192	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
PAILFIKI_02839	7.97e-59	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
PAILFIKI_02840	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PAILFIKI_02841	2.08e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PAILFIKI_02842	1.01e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PAILFIKI_02843	1.9e-22	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PAILFIKI_02844	4.18e-192	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PAILFIKI_02845	3.73e-264	-	-	-	V	-	-	-	Beta-lactamase
PAILFIKI_02846	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
PAILFIKI_02847	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_02848	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_02849	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_02850	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_02851	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
PAILFIKI_02852	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_02853	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
PAILFIKI_02854	1.73e-132	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
PAILFIKI_02855	7.91e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
PAILFIKI_02856	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PAILFIKI_02857	1.51e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
PAILFIKI_02858	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PAILFIKI_02859	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAILFIKI_02860	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PAILFIKI_02861	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
PAILFIKI_02862	5.27e-197	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
PAILFIKI_02863	1.68e-312	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
PAILFIKI_02864	6.37e-60	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
PAILFIKI_02865	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
PAILFIKI_02866	4.47e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
PAILFIKI_02867	1.2e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
PAILFIKI_02868	1.08e-214	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAILFIKI_02869	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PAILFIKI_02870	3.68e-50	ykoA	-	-	-	-	-	-	-
PAILFIKI_02871	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PAILFIKI_02872	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PAILFIKI_02873	5.54e-213	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
PAILFIKI_02874	9.28e-170	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_02875	2.98e-269	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
PAILFIKI_02876	2.38e-157	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_02877	1.64e-245	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAILFIKI_02878	7.69e-139	yknW	-	-	S	-	-	-	Yip1 domain
PAILFIKI_02879	2.06e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PAILFIKI_02880	7.17e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
PAILFIKI_02881	3.21e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
PAILFIKI_02882	2.78e-309	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
PAILFIKI_02883	1.41e-240	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PAILFIKI_02884	1.93e-139	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PAILFIKI_02885	6.93e-216	yknT	-	-	-	ko:K06437	-	ko00000	-
PAILFIKI_02886	3.04e-126	rok	-	-	K	-	-	-	Repressor of ComK
PAILFIKI_02887	1.92e-102	ykuV	-	-	CO	-	-	-	thiol-disulfide
PAILFIKI_02888	4.46e-12	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
PAILFIKI_02889	3.22e-135	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
PAILFIKI_02890	2.15e-52	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
PAILFIKI_02891	7.99e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PAILFIKI_02892	2.89e-129	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PAILFIKI_02893	2.16e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PAILFIKI_02894	1.95e-219	ykuO	-	-	-	-	-	-	-
PAILFIKI_02895	6.12e-115	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PAILFIKI_02896	1.32e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_02897	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
PAILFIKI_02898	3.09e-35	ykzF	-	-	S	-	-	-	Antirepressor AbbA
PAILFIKI_02899	4.35e-120	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
PAILFIKI_02900	3.63e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_02901	1.82e-295	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
PAILFIKI_02903	1.5e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAILFIKI_02904	3.66e-197	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
PAILFIKI_02905	2.55e-116	ykuD	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_02906	4.6e-308	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_02907	5.07e-108	ykyB	-	-	S	-	-	-	YkyB-like protein
PAILFIKI_02908	3.2e-212	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
PAILFIKI_02909	6.38e-15	-	-	-	-	-	-	-	-
PAILFIKI_02910	3.28e-275	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PAILFIKI_02911	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_02912	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PAILFIKI_02913	2.94e-168	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
PAILFIKI_02914	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PAILFIKI_02915	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
PAILFIKI_02916	1.42e-253	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
PAILFIKI_02917	3.63e-50	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_02918	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PAILFIKI_02919	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
PAILFIKI_02920	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_02921	4.61e-198	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
PAILFIKI_02922	1.01e-224	ykvZ	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_02924	4.71e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
PAILFIKI_02925	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
PAILFIKI_02926	8.57e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
PAILFIKI_02927	2.66e-306	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAILFIKI_02928	8.42e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
PAILFIKI_02929	7.17e-39	-	-	-	-	-	-	-	-
PAILFIKI_02930	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_02931	6e-59	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
PAILFIKI_02932	5.88e-32	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_02933	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
PAILFIKI_02934	7.97e-168	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PAILFIKI_02935	1.85e-312	-	6.1.3.1, 6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PAILFIKI_02938	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
PAILFIKI_02939	4.32e-122	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PAILFIKI_02940	1.42e-196	-	-	-	K	-	-	-	LysR substrate binding domain
PAILFIKI_02941	6.43e-66	-	-	-	S	-	-	-	GlpM protein
PAILFIKI_02942	7.32e-247	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PAILFIKI_02943	1.29e-188	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PAILFIKI_02944	3.37e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PAILFIKI_02945	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PAILFIKI_02946	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PAILFIKI_02947	1.92e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PAILFIKI_02948	1.3e-34	yqzJ	-	-	-	-	-	-	-
PAILFIKI_02949	1.68e-190	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PAILFIKI_02950	1.06e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
PAILFIKI_02951	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PAILFIKI_02952	1.33e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
PAILFIKI_02954	3.45e-85	yqjB	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_02955	4.58e-219	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
PAILFIKI_02956	2.89e-163	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
PAILFIKI_02957	4.25e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
PAILFIKI_02958	3.23e-172	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
PAILFIKI_02959	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
PAILFIKI_02960	4.77e-216	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PAILFIKI_02961	1.78e-284	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PAILFIKI_02962	9.83e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PAILFIKI_02963	4.56e-221	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PAILFIKI_02964	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PAILFIKI_02965	3.45e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
PAILFIKI_02966	2.61e-260	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
PAILFIKI_02967	1.67e-195	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
PAILFIKI_02968	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
PAILFIKI_02969	6.25e-47	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
PAILFIKI_02970	2.32e-204	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PAILFIKI_02971	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
PAILFIKI_02972	2.52e-263	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
PAILFIKI_02973	2.06e-259	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
PAILFIKI_02974	4.16e-198	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
PAILFIKI_02975	1.36e-53	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PAILFIKI_02976	1.1e-174	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PAILFIKI_02977	1.39e-136	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
PAILFIKI_02979	1.96e-131	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
PAILFIKI_02980	1.15e-145	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
PAILFIKI_02982	2.28e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PAILFIKI_02985	2.48e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PAILFIKI_02986	6.11e-187	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PAILFIKI_02987	8.85e-304	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
PAILFIKI_02988	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PAILFIKI_02989	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PAILFIKI_02990	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
PAILFIKI_02991	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PAILFIKI_02992	9.49e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PAILFIKI_02993	2.67e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PAILFIKI_02994	8.28e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PAILFIKI_02995	8.75e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PAILFIKI_02996	2.2e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PAILFIKI_02997	1.36e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_02998	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PAILFIKI_02999	4.67e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PAILFIKI_03000	2.74e-94	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
PAILFIKI_03001	2.35e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
PAILFIKI_03002	4.27e-130	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
PAILFIKI_03003	5.23e-261	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
PAILFIKI_03004	3.72e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
PAILFIKI_03005	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
PAILFIKI_03006	6.93e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
PAILFIKI_03007	1.27e-220	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
PAILFIKI_03008	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
PAILFIKI_03009	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PAILFIKI_03010	2.11e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
PAILFIKI_03011	9.4e-117	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
PAILFIKI_03012	7.33e-221	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
PAILFIKI_03013	7.65e-83	yqhP	-	-	-	-	-	-	-
PAILFIKI_03014	7e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
PAILFIKI_03015	5.64e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PAILFIKI_03016	1.58e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PAILFIKI_03017	3.18e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
PAILFIKI_03018	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PAILFIKI_03019	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PAILFIKI_03020	4.04e-265	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
PAILFIKI_03021	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
PAILFIKI_03022	8.78e-195	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
PAILFIKI_03023	2.71e-31	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
PAILFIKI_03024	2.75e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
PAILFIKI_03025	1.82e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
PAILFIKI_03026	3.13e-101	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
PAILFIKI_03027	1.28e-153	yqxM	-	-	-	ko:K19433	-	ko00000	-
PAILFIKI_03028	2.8e-70	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
PAILFIKI_03029	8.16e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
PAILFIKI_03030	2.62e-78	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
PAILFIKI_03031	2.66e-99	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
PAILFIKI_03032	3.14e-26	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
PAILFIKI_03033	2.27e-93	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
PAILFIKI_03034	4.46e-66	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
PAILFIKI_03035	9.79e-235	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
PAILFIKI_03036	3.84e-258	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PAILFIKI_03037	2.62e-238	yqxL	-	-	P	-	-	-	Mg2 transporter protein
PAILFIKI_03038	6.23e-303	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
PAILFIKI_03039	8.33e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PAILFIKI_03041	1.91e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
PAILFIKI_03042	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
PAILFIKI_03043	3.45e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
PAILFIKI_03044	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
PAILFIKI_03045	2.99e-65	dglA	-	-	S	-	-	-	Thiamine-binding protein
PAILFIKI_03046	2.4e-258	yqgU	-	-	-	-	-	-	-
PAILFIKI_03047	4.66e-280	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
PAILFIKI_03048	1.99e-140	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PAILFIKI_03049	1.21e-74	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PAILFIKI_03050	9.1e-39	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
PAILFIKI_03051	3.61e-276	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
PAILFIKI_03052	5.38e-11	yqgO	-	-	-	-	-	-	-
PAILFIKI_03053	8.62e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PAILFIKI_03054	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PAILFIKI_03055	3.42e-68	yqzD	-	-	-	-	-	-	-
PAILFIKI_03056	2.5e-99	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PAILFIKI_03057	5.46e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PAILFIKI_03058	5.62e-184	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PAILFIKI_03059	5.88e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
PAILFIKI_03060	1.75e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PAILFIKI_03061	2.72e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PAILFIKI_03062	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
PAILFIKI_03063	5.56e-288	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
PAILFIKI_03064	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
PAILFIKI_03065	1.12e-98	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
PAILFIKI_03066	1.08e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
PAILFIKI_03067	8.76e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
PAILFIKI_03068	1.97e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PAILFIKI_03069	3.34e-80	yqfX	-	-	S	-	-	-	membrane
PAILFIKI_03070	7.06e-143	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
PAILFIKI_03071	1.3e-99	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
PAILFIKI_03072	5.44e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
PAILFIKI_03073	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
PAILFIKI_03074	9.96e-213	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PAILFIKI_03075	2.8e-313	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PAILFIKI_03076	1.77e-78	yqfQ	-	-	S	-	-	-	YqfQ-like protein
PAILFIKI_03077	1.18e-224	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PAILFIKI_03078	6.25e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PAILFIKI_03079	1.72e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PAILFIKI_03080	9.68e-83	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
PAILFIKI_03081	3.97e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PAILFIKI_03082	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PAILFIKI_03083	5.52e-112	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
PAILFIKI_03084	5.46e-192	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PAILFIKI_03085	5.89e-145	ccpN	-	-	K	-	-	-	CBS domain
PAILFIKI_03086	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PAILFIKI_03087	5.19e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PAILFIKI_03088	8.73e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PAILFIKI_03089	6e-24	-	-	-	S	-	-	-	YqzL-like protein
PAILFIKI_03090	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PAILFIKI_03091	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PAILFIKI_03092	6.41e-84	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
PAILFIKI_03093	4.13e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PAILFIKI_03094	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
PAILFIKI_03095	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
PAILFIKI_03096	3.72e-282	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
PAILFIKI_03097	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
PAILFIKI_03098	1.52e-77	yqfB	-	-	-	-	-	-	-
PAILFIKI_03099	4.78e-177	yqfA	-	-	S	-	-	-	UPF0365 protein
PAILFIKI_03100	1.28e-293	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
PAILFIKI_03101	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
PAILFIKI_03102	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PAILFIKI_03103	1.37e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
PAILFIKI_03104	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
PAILFIKI_03105	1.01e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PAILFIKI_03106	1.09e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
PAILFIKI_03107	4.93e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PAILFIKI_03108	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PAILFIKI_03109	5.18e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PAILFIKI_03110	2.73e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PAILFIKI_03111	3.95e-274	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
PAILFIKI_03112	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PAILFIKI_03113	2.1e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
PAILFIKI_03114	2.14e-278	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
PAILFIKI_03115	2.51e-260	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PAILFIKI_03116	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PAILFIKI_03117	3.84e-234	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PAILFIKI_03118	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PAILFIKI_03119	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
PAILFIKI_03120	2.81e-134	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
PAILFIKI_03121	1.19e-192	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAILFIKI_03122	5.67e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
PAILFIKI_03123	4.65e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PAILFIKI_03124	6.89e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
PAILFIKI_03125	2.89e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PAILFIKI_03126	1.81e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
PAILFIKI_03127	1.2e-200	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAILFIKI_03128	3.23e-271	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PAILFIKI_03129	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
PAILFIKI_03131	3.99e-176	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PAILFIKI_03132	8.09e-181	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
PAILFIKI_03133	4.93e-138	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
PAILFIKI_03134	5.88e-32	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PAILFIKI_03135	3.28e-279	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PAILFIKI_03136	5.83e-35	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
PAILFIKI_03137	1.62e-140	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PAILFIKI_03138	1.6e-26	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
PAILFIKI_03140	1.04e-174	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Aldo/keto reductase family
PAILFIKI_03141	7.78e-91	-	-	-	K	-	-	-	MerR family transcriptional regulator
PAILFIKI_03142	4.67e-16	-	-	-	-	-	-	-	-
PAILFIKI_03143	3.83e-61	-	-	-	S	-	-	-	YjcQ protein
PAILFIKI_03144	3.43e-77	yjcP	-	-	-	-	-	-	-
PAILFIKI_03145	1.63e-77	yqaQ	-	-	L	-	-	-	Transposase
PAILFIKI_03146	1.03e-60	-	-	-	D	-	-	-	nuclear chromosome segregation
PAILFIKI_03148	1.03e-201	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
PAILFIKI_03149	2.6e-118	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
PAILFIKI_03150	1.84e-91	psiE	-	-	S	ko:K13256	-	ko00000	Belongs to the PsiE family
PAILFIKI_03151	1.27e-306	yrkQ	-	-	T	-	-	-	Histidine kinase
PAILFIKI_03152	7.69e-159	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
PAILFIKI_03153	8.05e-278	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
PAILFIKI_03155	2.4e-132	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
PAILFIKI_03156	5.27e-126	yqaC	-	-	F	-	-	-	adenylate kinase activity
PAILFIKI_03157	4.56e-34	-	-	-	K	-	-	-	acetyltransferase
PAILFIKI_03158	1.95e-282	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_03159	8.64e-105	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
PAILFIKI_03160	4.76e-121	-	-	-	S	-	-	-	DinB family
PAILFIKI_03161	2.06e-190	supH	-	-	S	-	-	-	hydrolase
PAILFIKI_03162	2.91e-187	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PAILFIKI_03163	2.9e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PAILFIKI_03164	3.44e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PAILFIKI_03165	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_03166	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
PAILFIKI_03167	2.81e-232	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
PAILFIKI_03168	1.13e-107	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PAILFIKI_03169	2.17e-210	yybE	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_03170	9.68e-273	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_03171	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
PAILFIKI_03172	4.77e-130	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
PAILFIKI_03173	5.97e-107	yrhH	-	-	Q	-	-	-	methyltransferase
PAILFIKI_03174	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
PAILFIKI_03175	3.96e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
PAILFIKI_03176	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
PAILFIKI_03177	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
PAILFIKI_03178	6.49e-104	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
PAILFIKI_03179	1.92e-46	yrhC	-	-	S	-	-	-	YrhC-like protein
PAILFIKI_03180	2.56e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PAILFIKI_03181	2.09e-69	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
PAILFIKI_03182	9.08e-96	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
PAILFIKI_03183	8.02e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PAILFIKI_03184	2.83e-152	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
PAILFIKI_03185	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
PAILFIKI_03186	2.92e-123	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
PAILFIKI_03187	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
PAILFIKI_03188	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PAILFIKI_03189	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PAILFIKI_03190	1.09e-311	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
PAILFIKI_03191	3.64e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
PAILFIKI_03192	2.32e-153	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
PAILFIKI_03193	4.67e-258	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PAILFIKI_03194	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PAILFIKI_03195	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PAILFIKI_03196	1.1e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PAILFIKI_03197	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PAILFIKI_03198	1.15e-237	yrrI	-	-	S	-	-	-	AI-2E family transporter
PAILFIKI_03199	4.45e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
PAILFIKI_03200	3.14e-189	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
PAILFIKI_03201	1.13e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PAILFIKI_03202	1.54e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PAILFIKI_03203	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
PAILFIKI_03204	8.4e-42	yrzR	-	-	-	-	-	-	-
PAILFIKI_03205	3.14e-103	yrrD	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_03206	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PAILFIKI_03207	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
PAILFIKI_03208	3.55e-282	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PAILFIKI_03209	4.24e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
PAILFIKI_03210	9.19e-84	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_03211	7.55e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PAILFIKI_03212	9.74e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PAILFIKI_03213	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PAILFIKI_03214	4.97e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PAILFIKI_03217	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
PAILFIKI_03218	2.86e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PAILFIKI_03219	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PAILFIKI_03220	5.1e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PAILFIKI_03221	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PAILFIKI_03222	2.23e-62	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PAILFIKI_03223	1.26e-111	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
PAILFIKI_03224	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PAILFIKI_03225	3.45e-68	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
PAILFIKI_03226	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAILFIKI_03227	4.79e-142	yrbG	-	-	S	-	-	-	membrane
PAILFIKI_03228	9.08e-81	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
PAILFIKI_03229	2.09e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
PAILFIKI_03230	8.2e-293	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PAILFIKI_03231	5.79e-246	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PAILFIKI_03232	9.76e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
PAILFIKI_03233	3.57e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PAILFIKI_03234	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PAILFIKI_03235	1.21e-120	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
PAILFIKI_03237	8.92e-61	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PAILFIKI_03238	6.31e-250	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
PAILFIKI_03239	4.96e-271	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PAILFIKI_03240	1.23e-194	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
PAILFIKI_03241	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
PAILFIKI_03242	7.79e-283	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
PAILFIKI_03243	1.96e-120	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
PAILFIKI_03244	8.16e-206	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
PAILFIKI_03245	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
PAILFIKI_03246	2.89e-310	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PAILFIKI_03247	2.87e-137	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
PAILFIKI_03248	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PAILFIKI_03249	1.42e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
PAILFIKI_03250	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PAILFIKI_03251	4.19e-205	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
PAILFIKI_03252	1.39e-188	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
PAILFIKI_03253	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
PAILFIKI_03254	4.62e-153	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PAILFIKI_03255	6.14e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
PAILFIKI_03256	4.34e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PAILFIKI_03257	1.06e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
PAILFIKI_03258	2.5e-164	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
PAILFIKI_03259	2.36e-130	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
PAILFIKI_03260	8.52e-207	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
PAILFIKI_03261	1.27e-171	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PAILFIKI_03262	2.28e-308	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PAILFIKI_03263	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PAILFIKI_03264	4.38e-35	-	-	-	-	-	-	-	-
PAILFIKI_03265	1.89e-251	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PAILFIKI_03266	8.92e-173	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
PAILFIKI_03267	2.68e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
PAILFIKI_03268	3.43e-236	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
PAILFIKI_03269	1.56e-181	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
PAILFIKI_03270	5.19e-223	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PAILFIKI_03271	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
PAILFIKI_03272	4.36e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PAILFIKI_03273	6.04e-47	ysxD	-	-	-	-	-	-	-
PAILFIKI_03274	1.79e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PAILFIKI_03275	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PAILFIKI_03276	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
PAILFIKI_03277	3.28e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PAILFIKI_03278	2.18e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PAILFIKI_03279	3.33e-241	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
PAILFIKI_03280	1.53e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PAILFIKI_03281	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PAILFIKI_03282	4.12e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PAILFIKI_03283	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PAILFIKI_03284	2.75e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PAILFIKI_03285	2.06e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
PAILFIKI_03286	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
PAILFIKI_03289	9.55e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
PAILFIKI_03290	1.59e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PAILFIKI_03291	1.18e-169	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PAILFIKI_03292	5.21e-254	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
PAILFIKI_03293	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PAILFIKI_03294	3.77e-97	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PAILFIKI_03295	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_03296	8.94e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
PAILFIKI_03297	4.34e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
PAILFIKI_03298	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
PAILFIKI_03299	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
PAILFIKI_03300	2.45e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PAILFIKI_03301	1.74e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PAILFIKI_03302	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PAILFIKI_03303	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PAILFIKI_03304	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
PAILFIKI_03305	2.48e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
PAILFIKI_03306	1.23e-177	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
PAILFIKI_03307	1.43e-177	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
PAILFIKI_03308	6.22e-134	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_03309	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PAILFIKI_03310	2.11e-50	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
PAILFIKI_03311	1.12e-93	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
PAILFIKI_03312	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
PAILFIKI_03313	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PAILFIKI_03314	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
PAILFIKI_03315	6.04e-109	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
PAILFIKI_03316	1.47e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PAILFIKI_03317	3.08e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PAILFIKI_03318	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PAILFIKI_03319	2.19e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PAILFIKI_03320	2.2e-171	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAILFIKI_03321	1.07e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
PAILFIKI_03322	5.07e-261	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
PAILFIKI_03323	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
PAILFIKI_03324	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
PAILFIKI_03325	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
PAILFIKI_03326	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
PAILFIKI_03327	1.18e-191	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
PAILFIKI_03328	4.38e-215	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
PAILFIKI_03329	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
PAILFIKI_03330	1.55e-231	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PAILFIKI_03331	6.57e-180	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
PAILFIKI_03332	3.43e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PAILFIKI_03333	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
PAILFIKI_03334	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
PAILFIKI_03335	1.11e-237	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
PAILFIKI_03336	1.85e-263	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
PAILFIKI_03337	6.58e-88	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
PAILFIKI_03338	1.34e-56	ysdA	-	-	S	-	-	-	Membrane
PAILFIKI_03339	2.3e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PAILFIKI_03340	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PAILFIKI_03341	1.79e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PAILFIKI_03342	3.1e-147	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PAILFIKI_03343	1.59e-68	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
PAILFIKI_03344	1.05e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
PAILFIKI_03345	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PAILFIKI_03346	1.2e-192	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
PAILFIKI_03347	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PAILFIKI_03348	2.77e-145	ytxC	-	-	S	-	-	-	YtxC-like family
PAILFIKI_03349	1.05e-138	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
PAILFIKI_03350	2.02e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PAILFIKI_03351	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
PAILFIKI_03352	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PAILFIKI_03353	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PAILFIKI_03354	1.48e-247	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PAILFIKI_03355	1.69e-89	ytcD	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_03356	8e-259	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
PAILFIKI_03357	4.54e-205	ytbE	-	-	S	-	-	-	reductase
PAILFIKI_03358	5.08e-129	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PAILFIKI_03359	2.84e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
PAILFIKI_03360	1.64e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PAILFIKI_03361	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PAILFIKI_03362	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
PAILFIKI_03363	2.38e-164	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_03364	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
PAILFIKI_03365	1.08e-307	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
PAILFIKI_03366	1.42e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
PAILFIKI_03367	1.35e-69	-	-	-	-	-	-	-	-
PAILFIKI_03368	9.5e-84	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
PAILFIKI_03369	5.65e-96	ytwI	-	-	S	-	-	-	membrane
PAILFIKI_03370	4.05e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
PAILFIKI_03371	3.42e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
PAILFIKI_03372	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PAILFIKI_03373	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PAILFIKI_03374	1.15e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PAILFIKI_03375	8.46e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PAILFIKI_03376	4.23e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
PAILFIKI_03377	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PAILFIKI_03378	4.94e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
PAILFIKI_03379	2.64e-114	ytrI	-	-	-	-	-	-	-
PAILFIKI_03380	7.04e-32	-	-	-	-	-	-	-	-
PAILFIKI_03381	2.14e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
PAILFIKI_03382	3.57e-62	ytpI	-	-	S	-	-	-	YtpI-like protein
PAILFIKI_03383	7.89e-304	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
PAILFIKI_03384	4.16e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
PAILFIKI_03385	8.38e-184	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAILFIKI_03387	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PAILFIKI_03388	2.49e-296	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PAILFIKI_03389	1.64e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
PAILFIKI_03390	2.33e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PAILFIKI_03391	8.37e-232	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
PAILFIKI_03392	1.36e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PAILFIKI_03393	4.77e-100	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
PAILFIKI_03394	1.22e-154	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
PAILFIKI_03395	2.77e-114	yteJ	-	-	S	-	-	-	RDD family
PAILFIKI_03396	6.39e-235	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
PAILFIKI_03397	2.32e-196	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PAILFIKI_03398	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
PAILFIKI_03399	8.32e-51	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PAILFIKI_03400	1.01e-265	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PAILFIKI_03401	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
PAILFIKI_03402	2.09e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PAILFIKI_03403	1.12e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
PAILFIKI_03404	9.7e-309	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PAILFIKI_03405	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PAILFIKI_03406	1.99e-194	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PAILFIKI_03407	2.82e-140	yttP	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_03408	5.2e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PAILFIKI_03409	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
PAILFIKI_03410	2.59e-07	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
PAILFIKI_03411	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PAILFIKI_03412	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PAILFIKI_03413	3.13e-133	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
PAILFIKI_03415	9e-60	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
PAILFIKI_03416	7.11e-19	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PAILFIKI_03418	2.3e-23	-	-	-	-	-	-	-	-
PAILFIKI_03419	1.58e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PAILFIKI_03421	1.65e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
PAILFIKI_03423	2.39e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PAILFIKI_03424	1.43e-192	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAILFIKI_03425	9.06e-190	-	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_03426	2.86e-160	ygaZ	-	-	E	-	-	-	AzlC protein
PAILFIKI_03427	8.79e-64	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
PAILFIKI_03428	5.98e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PAILFIKI_03429	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PAILFIKI_03430	2.84e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PAILFIKI_03431	2.06e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
PAILFIKI_03432	1.94e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
PAILFIKI_03433	4.99e-154	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
PAILFIKI_03434	5.2e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
PAILFIKI_03435	1.39e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PAILFIKI_03436	1.54e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PAILFIKI_03437	1.19e-57	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
PAILFIKI_03438	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
PAILFIKI_03439	5.38e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PAILFIKI_03440	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PAILFIKI_03441	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PAILFIKI_03442	2.08e-139	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PAILFIKI_03443	2.4e-190	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
PAILFIKI_03444	5.47e-76	ytpP	-	-	CO	-	-	-	Thioredoxin
PAILFIKI_03445	1.94e-100	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
PAILFIKI_03446	5.06e-259	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
PAILFIKI_03447	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
PAILFIKI_03448	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
PAILFIKI_03449	4.38e-208	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
PAILFIKI_03450	1.07e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PAILFIKI_03451	5.51e-60	ytzH	-	-	S	-	-	-	YtzH-like protein
PAILFIKI_03452	2.93e-199	ytmP	-	-	M	-	-	-	Phosphotransferase
PAILFIKI_03453	1.61e-224	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PAILFIKI_03454	1.47e-216	ytlQ	-	-	-	-	-	-	-
PAILFIKI_03455	6.34e-132	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PAILFIKI_03456	6.81e-222	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PAILFIKI_03457	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
PAILFIKI_03458	1.48e-290	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PAILFIKI_03459	1.75e-276	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
PAILFIKI_03460	2.58e-163	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PAILFIKI_03461	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
PAILFIKI_03462	5.02e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PAILFIKI_03463	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAILFIKI_03464	3.73e-299	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
PAILFIKI_03465	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
PAILFIKI_03466	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
PAILFIKI_03467	7.81e-239	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PAILFIKI_03468	3.24e-310	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PAILFIKI_03469	2.44e-212	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PAILFIKI_03470	2.88e-184	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
PAILFIKI_03471	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
PAILFIKI_03472	6.9e-111	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
PAILFIKI_03473	3.51e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
PAILFIKI_03474	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PAILFIKI_03475	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
PAILFIKI_03476	4.59e-175	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PAILFIKI_03477	3.35e-269	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
PAILFIKI_03478	1.55e-162	ywaF	-	-	S	-	-	-	Integral membrane protein
PAILFIKI_03479	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
PAILFIKI_03480	4.63e-174	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_03481	4.66e-232	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
PAILFIKI_03482	9.07e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAILFIKI_03483	4.75e-288	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
PAILFIKI_03484	2.12e-161	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_03485	2.02e-206	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
PAILFIKI_03486	2.68e-228	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
PAILFIKI_03487	4.31e-213	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
PAILFIKI_03488	4.38e-209	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PAILFIKI_03489	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
PAILFIKI_03491	1.43e-52	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
PAILFIKI_03492	5.76e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
PAILFIKI_03493	1.26e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
PAILFIKI_03495	1.49e-184	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
PAILFIKI_03496	2.02e-271	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
PAILFIKI_03497	6.95e-194	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
PAILFIKI_03498	4.06e-84	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PAILFIKI_03499	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
PAILFIKI_03500	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PAILFIKI_03501	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PAILFIKI_03502	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PAILFIKI_03503	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
PAILFIKI_03504	1.84e-188	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PAILFIKI_03505	1.07e-237	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PAILFIKI_03506	3.39e-181	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PAILFIKI_03507	5.66e-169	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PAILFIKI_03508	1.01e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
PAILFIKI_03509	1.23e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
PAILFIKI_03510	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PAILFIKI_03512	1.26e-100	ytkA	-	-	S	-	-	-	YtkA-like
PAILFIKI_03513	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PAILFIKI_03514	8.41e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PAILFIKI_03515	9.31e-137	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
PAILFIKI_03516	1.23e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PAILFIKI_03517	4.48e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
PAILFIKI_03518	1.06e-234	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PAILFIKI_03519	1.92e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
PAILFIKI_03520	2.88e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PAILFIKI_03521	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PAILFIKI_03522	7.52e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PAILFIKI_03523	2.52e-199	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PAILFIKI_03524	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PAILFIKI_03525	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
PAILFIKI_03526	3.03e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
PAILFIKI_03527	1.82e-102	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
PAILFIKI_03531	4e-233	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PAILFIKI_03532	9.02e-113	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
PAILFIKI_03533	1.02e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
PAILFIKI_03534	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PAILFIKI_03535	6.49e-245	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PAILFIKI_03536	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
PAILFIKI_03537	2.84e-115	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PAILFIKI_03538	1.29e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PAILFIKI_03539	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PAILFIKI_03540	1.92e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PAILFIKI_03541	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
PAILFIKI_03542	2.27e-162	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PAILFIKI_03543	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PAILFIKI_03544	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PAILFIKI_03545	0.0	yvfT	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
PAILFIKI_03546	2.24e-127	-	-	-	S	-	-	-	Putative sensor
PAILFIKI_03547	0.0	pbpX	-	-	V	-	-	-	Beta-lactamase
PAILFIKI_03548	2.41e-98	yfiJ	-	-	T	-	-	-	helix_turn_helix, Lux Regulon
PAILFIKI_03549	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
PAILFIKI_03550	1.69e-255	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
PAILFIKI_03551	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
PAILFIKI_03552	5.78e-219	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
PAILFIKI_03553	3.61e-41	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
PAILFIKI_03554	9.58e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
PAILFIKI_03555	3.49e-226	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PAILFIKI_03556	4.16e-160	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
PAILFIKI_03557	3.22e-223	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
PAILFIKI_03558	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
PAILFIKI_03559	9.73e-194	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
PAILFIKI_03560	1.87e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PAILFIKI_03561	1e-248	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
PAILFIKI_03562	1.6e-82	ydjM	-	-	M	-	-	-	Lytic transglycolase
PAILFIKI_03563	7.08e-195	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
PAILFIKI_03565	2.02e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
PAILFIKI_03566	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
PAILFIKI_03567	6.75e-309	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
PAILFIKI_03568	3.25e-225	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
PAILFIKI_03569	3.13e-274	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PAILFIKI_03570	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
PAILFIKI_03571	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PAILFIKI_03572	7.01e-102	-	-	-	-	-	-	-	-
PAILFIKI_03573	1.9e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
PAILFIKI_03574	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
PAILFIKI_03575	1.23e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PAILFIKI_03576	2.16e-168	yebC	-	-	M	-	-	-	Membrane
PAILFIKI_03578	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
PAILFIKI_03579	2.21e-38	yebG	-	-	S	-	-	-	NETI protein
PAILFIKI_03580	3.78e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PAILFIKI_03581	4.56e-287	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PAILFIKI_03582	2.59e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PAILFIKI_03583	2.79e-165	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PAILFIKI_03584	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAILFIKI_03585	1.34e-166	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAILFIKI_03586	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAILFIKI_03587	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PAILFIKI_03588	1.46e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PAILFIKI_03589	9.96e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PAILFIKI_03590	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PAILFIKI_03591	8.44e-300	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PAILFIKI_03592	1.03e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
PAILFIKI_03593	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
PAILFIKI_03594	4.95e-246	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
PAILFIKI_03595	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_03596	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
PAILFIKI_03597	8.71e-164	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PAILFIKI_03598	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PAILFIKI_03599	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PAILFIKI_03600	5.54e-286	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
PAILFIKI_03601	2.19e-249	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
PAILFIKI_03602	1.44e-158	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
PAILFIKI_03603	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAILFIKI_03604	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PAILFIKI_03605	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PAILFIKI_03606	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PAILFIKI_03607	3.16e-197	yerO	-	-	K	-	-	-	Transcriptional regulator
PAILFIKI_03608	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAILFIKI_03609	7.33e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PAILFIKI_03610	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAILFIKI_03611	0.0	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PAILFIKI_03612	9.62e-203	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PAILFIKI_03613	6.78e-176	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PAILFIKI_03614	2.31e-80	-	-	-	S	-	-	-	Protein of unknown function, DUF600
PAILFIKI_03615	8.27e-67	-	-	-	S	-	-	-	Protein of unknown function, DUF600
PAILFIKI_03616	2.57e-60	-	-	-	S	-	-	-	Protein of unknown function, DUF600
PAILFIKI_03617	7.72e-68	-	-	-	S	-	-	-	Protein of unknown function, DUF600
PAILFIKI_03618	2.38e-101	-	-	-	S	-	-	-	Protein of unknown function, DUF600
PAILFIKI_03619	2.34e-278	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
PAILFIKI_03620	3.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
PAILFIKI_03622	2.21e-138	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
PAILFIKI_03623	2.67e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
PAILFIKI_03624	1.62e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
PAILFIKI_03625	1.48e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
PAILFIKI_03626	1.39e-123	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
PAILFIKI_03627	5.92e-05	-	-	-	-	-	-	-	-
PAILFIKI_03628	8.99e-157	yetF	-	-	S	-	-	-	membrane
PAILFIKI_03629	1.11e-72	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
PAILFIKI_03630	3.78e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAILFIKI_03631	6.28e-197	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PAILFIKI_03632	1.34e-31	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
PAILFIKI_03633	1.82e-73	-	-	-	H	-	-	-	riboflavin kinase activity
PAILFIKI_03634	1.8e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PAILFIKI_03635	3.45e-116	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PAILFIKI_03636	2.19e-267	yetM	-	-	CH	-	-	-	FAD binding domain
PAILFIKI_03637	2.28e-250	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
PAILFIKI_03638	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
PAILFIKI_03640	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
PAILFIKI_03641	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
PAILFIKI_03642	3.93e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
PAILFIKI_03643	1.9e-229	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
PAILFIKI_03644	7.24e-285	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
PAILFIKI_03645	1.99e-238	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
PAILFIKI_03646	1.56e-277	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_03647	8.39e-313	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
PAILFIKI_03648	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PAILFIKI_03649	2.85e-169	yfmS	-	-	NT	-	-	-	chemotaxis protein
PAILFIKI_03650	1.72e-214	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
PAILFIKI_03651	1.2e-265	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
PAILFIKI_03652	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PAILFIKI_03653	2.05e-89	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
PAILFIKI_03654	5.93e-263	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
PAILFIKI_03655	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PAILFIKI_03656	1.78e-264	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
PAILFIKI_03657	9.42e-83	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
PAILFIKI_03658	1.84e-236	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
PAILFIKI_03659	7.35e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
PAILFIKI_03660	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
PAILFIKI_03661	3.93e-309	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
PAILFIKI_03662	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PAILFIKI_03667	9.55e-90	M1-820	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
PAILFIKI_03668	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
PAILFIKI_03669	1.38e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PAILFIKI_03670	5.87e-228	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
PAILFIKI_03671	1.74e-202	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
PAILFIKI_03672	3.47e-51	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
PAILFIKI_03673	1.4e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
PAILFIKI_03674	1.74e-278	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PAILFIKI_03675	4.77e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PAILFIKI_03676	2.82e-155	yflK	-	-	S	-	-	-	protein conserved in bacteria
PAILFIKI_03677	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
PAILFIKI_03678	1.98e-26	yflI	-	-	-	-	-	-	-
PAILFIKI_03679	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
PAILFIKI_03680	9.02e-176	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
PAILFIKI_03681	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PAILFIKI_03682	2.02e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
PAILFIKI_03683	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
PAILFIKI_03684	8.46e-84	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
PAILFIKI_03685	1.18e-103	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PAILFIKI_03686	6.73e-51	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
PAILFIKI_03687	5.99e-50	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
PAILFIKI_03688	1.57e-313	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_03689	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
PAILFIKI_03690	1.18e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
PAILFIKI_03691	2.93e-158	frp	-	-	C	-	-	-	nitroreductase
PAILFIKI_03692	6e-167	yibF	-	-	S	-	-	-	YibE/F-like protein
PAILFIKI_03693	1.02e-246	yibE	-	-	S	-	-	-	YibE/F-like protein
PAILFIKI_03694	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
PAILFIKI_03695	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
PAILFIKI_03696	6.43e-239	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PAILFIKI_03697	5.86e-208	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAILFIKI_03698	3.38e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PAILFIKI_03699	6.98e-252	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_03700	1.47e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
PAILFIKI_03701	1.69e-112	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAILFIKI_03702	3.7e-70	yfkI	-	-	S	-	-	-	gas vesicle protein
PAILFIKI_03703	1.95e-185	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PAILFIKI_03704	6.71e-12	-	-	-	-	-	-	-	-
PAILFIKI_03705	4.6e-265	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
PAILFIKI_03706	1.4e-237	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
PAILFIKI_03707	1.62e-185	yfkD	-	-	S	-	-	-	YfkD-like protein
PAILFIKI_03708	5.2e-189	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
PAILFIKI_03709	2.92e-282	yfkA	-	-	S	-	-	-	YfkB-like domain
PAILFIKI_03710	7.99e-37	yfjT	-	-	-	-	-	-	-
PAILFIKI_03711	3.59e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
PAILFIKI_03712	4.82e-184	-	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PAILFIKI_03713	1.12e-103	-	-	-	S	ko:K19310	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacitracin ABC transporter permease
PAILFIKI_03714	8.75e-92	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin ABC transporter permease
PAILFIKI_03715	4.57e-138	-	-	-	K	-	-	-	Two component transcriptional regulator, winged helix family
PAILFIKI_03716	2.8e-139	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
PAILFIKI_03717	1.09e-190	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PAILFIKI_03719	3.71e-235	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
PAILFIKI_03720	5.07e-201	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PAILFIKI_03721	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAILFIKI_03722	1.64e-62	-	-	-	S	-	-	-	YfzA-like protein
PAILFIKI_03723	3.47e-244	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAILFIKI_03724	6.01e-115	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
PAILFIKI_03725	6.48e-243	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PAILFIKI_03726	1.52e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PAILFIKI_03727	5.38e-272	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PAILFIKI_03728	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PAILFIKI_03729	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
PAILFIKI_03730	6.64e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
PAILFIKI_03731	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PAILFIKI_03732	9.01e-178	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PAILFIKI_03733	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PAILFIKI_03734	3.72e-228	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
PAILFIKI_03735	1.89e-279	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
PAILFIKI_03736	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PAILFIKI_03737	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
PAILFIKI_03738	5.54e-82	yfiD3	-	-	S	-	-	-	DoxX
PAILFIKI_03739	4.72e-205	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
PAILFIKI_03740	7.58e-217	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PAILFIKI_03741	5.62e-126	padR	-	-	K	-	-	-	transcriptional
PAILFIKI_03742	1.79e-144	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PAILFIKI_03743	7.69e-236	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PAILFIKI_03744	0.0	-	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
PAILFIKI_03745	2.36e-60	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
PAILFIKI_03746	1.14e-128	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
PAILFIKI_03747	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
PAILFIKI_03748	7.97e-108	yfiV	-	-	K	-	-	-	transcriptional
PAILFIKI_03749	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PAILFIKI_03750	7.26e-209	yfhB	-	-	S	-	-	-	PhzF family
PAILFIKI_03751	1.94e-136	yfhC	-	-	C	-	-	-	nitroreductase
PAILFIKI_03752	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
PAILFIKI_03754	3.91e-137	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
PAILFIKI_03755	1.67e-43	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
PAILFIKI_03756	3.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
PAILFIKI_03757	1.12e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
PAILFIKI_03758	2.86e-268	yfhI	-	-	EGP	-	-	-	-transporter
PAILFIKI_03760	3.34e-214	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
PAILFIKI_03761	2.57e-59	yfhJ	-	-	S	-	-	-	WVELL protein
PAILFIKI_03762	3.85e-120	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
PAILFIKI_03763	2.99e-57	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
PAILFIKI_03764	6.8e-219	-	-	-	S	-	-	-	Alpha/beta hydrolase family
PAILFIKI_03765	1.57e-235	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
PAILFIKI_03766	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
PAILFIKI_03767	2.94e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
PAILFIKI_03768	9.18e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
PAILFIKI_03769	2.54e-50	yfhS	-	-	-	-	-	-	-
PAILFIKI_03770	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAILFIKI_03771	7.33e-07	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
PAILFIKI_03772	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
PAILFIKI_03773	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
PAILFIKI_03774	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
PAILFIKI_03775	5.27e-239	ygaE	-	-	S	-	-	-	Membrane
PAILFIKI_03776	2.79e-313	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
PAILFIKI_03777	3.28e-110	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
PAILFIKI_03778	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
PAILFIKI_03779	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
PAILFIKI_03780	1.12e-212	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like