ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HBCFODLC_00001 3.3e-86 - - - - - - - -
HBCFODLC_00002 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
HBCFODLC_00003 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBCFODLC_00004 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HBCFODLC_00005 2.32e-151 - - - S - - - Protein of unknown function (DUF1461)
HBCFODLC_00006 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HBCFODLC_00007 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
HBCFODLC_00008 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HBCFODLC_00009 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
HBCFODLC_00010 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HBCFODLC_00011 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBCFODLC_00012 7.43e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HBCFODLC_00014 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
HBCFODLC_00015 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
HBCFODLC_00016 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HBCFODLC_00017 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HBCFODLC_00018 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HBCFODLC_00019 1.55e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HBCFODLC_00020 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBCFODLC_00021 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
HBCFODLC_00022 8.49e-66 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
HBCFODLC_00023 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
HBCFODLC_00024 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HBCFODLC_00025 2.68e-276 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HBCFODLC_00026 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
HBCFODLC_00027 1.6e-96 - - - - - - - -
HBCFODLC_00028 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HBCFODLC_00029 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HBCFODLC_00030 6.72e-289 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HBCFODLC_00031 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HBCFODLC_00032 7.94e-114 ykuL - - S - - - (CBS) domain
HBCFODLC_00033 4.03e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HBCFODLC_00034 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HBCFODLC_00035 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HBCFODLC_00036 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
HBCFODLC_00037 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HBCFODLC_00038 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HBCFODLC_00039 1.29e-50 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HBCFODLC_00040 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
HBCFODLC_00041 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBCFODLC_00042 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
HBCFODLC_00043 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBCFODLC_00044 1.86e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HBCFODLC_00045 4.12e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HBCFODLC_00046 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBCFODLC_00047 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HBCFODLC_00048 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HBCFODLC_00049 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HBCFODLC_00050 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HBCFODLC_00051 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HBCFODLC_00052 1.25e-119 - - - - - - - -
HBCFODLC_00053 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HBCFODLC_00054 1.35e-93 - - - - - - - -
HBCFODLC_00055 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBCFODLC_00056 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HBCFODLC_00057 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
HBCFODLC_00058 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HBCFODLC_00059 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HBCFODLC_00060 1.15e-296 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HBCFODLC_00061 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBCFODLC_00062 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HBCFODLC_00063 0.0 ymfH - - S - - - Peptidase M16
HBCFODLC_00064 8.72e-297 ymfF - - S - - - Peptidase M16 inactive domain protein
HBCFODLC_00065 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HBCFODLC_00066 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HBCFODLC_00067 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_00068 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HBCFODLC_00069 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HBCFODLC_00070 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HBCFODLC_00071 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HBCFODLC_00072 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HBCFODLC_00073 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HBCFODLC_00074 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
HBCFODLC_00075 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HBCFODLC_00076 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HBCFODLC_00077 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HBCFODLC_00078 5.71e-302 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
HBCFODLC_00079 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBCFODLC_00080 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HBCFODLC_00081 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HBCFODLC_00082 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HBCFODLC_00083 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HBCFODLC_00084 3.73e-150 yktB - - S - - - Belongs to the UPF0637 family
HBCFODLC_00085 1.2e-106 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HBCFODLC_00086 1.57e-142 - - - S - - - Protein of unknown function (DUF1648)
HBCFODLC_00087 5.51e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HBCFODLC_00088 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HBCFODLC_00089 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HBCFODLC_00090 1.34e-52 - - - - - - - -
HBCFODLC_00091 2.37e-107 uspA - - T - - - universal stress protein
HBCFODLC_00092 1.2e-262 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HBCFODLC_00093 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
HBCFODLC_00094 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HBCFODLC_00095 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HBCFODLC_00096 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HBCFODLC_00097 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
HBCFODLC_00098 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HBCFODLC_00099 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HBCFODLC_00100 1.04e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_00101 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBCFODLC_00102 3.89e-65 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HBCFODLC_00103 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HBCFODLC_00104 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
HBCFODLC_00105 5.3e-58 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HBCFODLC_00106 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HBCFODLC_00107 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HBCFODLC_00108 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBCFODLC_00109 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HBCFODLC_00110 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HBCFODLC_00111 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HBCFODLC_00112 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HBCFODLC_00113 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBCFODLC_00114 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HBCFODLC_00115 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBCFODLC_00116 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HBCFODLC_00117 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HBCFODLC_00118 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
HBCFODLC_00119 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HBCFODLC_00120 4.63e-135 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HBCFODLC_00121 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HBCFODLC_00122 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HBCFODLC_00123 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HBCFODLC_00124 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HBCFODLC_00125 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HBCFODLC_00126 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HBCFODLC_00127 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HBCFODLC_00128 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
HBCFODLC_00129 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HBCFODLC_00130 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HBCFODLC_00131 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HBCFODLC_00132 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HBCFODLC_00133 1.88e-226 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBCFODLC_00134 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HBCFODLC_00136 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
HBCFODLC_00137 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HBCFODLC_00138 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HBCFODLC_00139 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HBCFODLC_00140 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HBCFODLC_00141 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HBCFODLC_00142 5.11e-171 - - - - - - - -
HBCFODLC_00143 0.0 eriC - - P ko:K03281 - ko00000 chloride
HBCFODLC_00144 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HBCFODLC_00145 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HBCFODLC_00146 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HBCFODLC_00147 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HBCFODLC_00148 0.0 - - - M - - - Domain of unknown function (DUF5011)
HBCFODLC_00149 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_00150 4.64e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_00151 5.62e-137 - - - - - - - -
HBCFODLC_00152 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HBCFODLC_00153 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HBCFODLC_00154 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HBCFODLC_00155 2.24e-106 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HBCFODLC_00156 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
HBCFODLC_00157 7.18e-131 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HBCFODLC_00158 2.53e-198 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HBCFODLC_00159 3.09e-213 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
HBCFODLC_00160 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HBCFODLC_00161 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
HBCFODLC_00162 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HBCFODLC_00163 6.9e-157 - - - S - - - Protein of unknown function (DUF1361)
HBCFODLC_00164 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HBCFODLC_00165 2.18e-182 ybbR - - S - - - YbbR-like protein
HBCFODLC_00166 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBCFODLC_00167 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HBCFODLC_00168 5.44e-159 - - - T - - - EAL domain
HBCFODLC_00169 9.79e-191 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
HBCFODLC_00170 1.47e-136 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_00171 1.46e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HBCFODLC_00172 3.38e-70 - - - - - - - -
HBCFODLC_00173 3.03e-96 - - - - - - - -
HBCFODLC_00174 1.73e-169 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HBCFODLC_00175 7.34e-180 - - - EGP - - - Transmembrane secretion effector
HBCFODLC_00176 1.15e-41 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HBCFODLC_00177 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBCFODLC_00178 1.57e-186 - - - - - - - -
HBCFODLC_00180 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
HBCFODLC_00181 3.88e-46 - - - - - - - -
HBCFODLC_00182 2.63e-120 - - - V - - - VanZ like family
HBCFODLC_00183 2.61e-316 - - - EGP - - - Major Facilitator
HBCFODLC_00184 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HBCFODLC_00185 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HBCFODLC_00186 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HBCFODLC_00187 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
HBCFODLC_00188 2.61e-108 - - - K - - - Transcriptional regulator
HBCFODLC_00189 1.36e-27 - - - - - - - -
HBCFODLC_00190 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HBCFODLC_00191 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HBCFODLC_00192 3.3e-199 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HBCFODLC_00193 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HBCFODLC_00194 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HBCFODLC_00195 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HBCFODLC_00196 0.0 oatA - - I - - - Acyltransferase
HBCFODLC_00197 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HBCFODLC_00198 1.89e-90 - - - O - - - OsmC-like protein
HBCFODLC_00199 1.21e-63 - - - - - - - -
HBCFODLC_00200 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HBCFODLC_00201 6.12e-115 - - - - - - - -
HBCFODLC_00202 7.76e-193 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HBCFODLC_00203 7.48e-96 - - - F - - - Nudix hydrolase
HBCFODLC_00204 1.48e-27 - - - - - - - -
HBCFODLC_00205 8.9e-137 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HBCFODLC_00206 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HBCFODLC_00207 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HBCFODLC_00208 1.01e-188 - - - - - - - -
HBCFODLC_00209 5.95e-147 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
HBCFODLC_00210 0.0 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HBCFODLC_00211 1.28e-54 - - - - - - - -
HBCFODLC_00213 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_00214 1.18e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HBCFODLC_00215 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_00216 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_00217 2.1e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HBCFODLC_00218 4.68e-198 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HBCFODLC_00219 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HBCFODLC_00220 1.57e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
HBCFODLC_00221 0.0 steT - - E ko:K03294 - ko00000 amino acid
HBCFODLC_00222 3.1e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HBCFODLC_00223 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
HBCFODLC_00224 3.08e-93 - - - K - - - MarR family
HBCFODLC_00225 2.27e-269 - - - EGP - - - Major Facilitator Superfamily
HBCFODLC_00226 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
HBCFODLC_00227 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_00228 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBCFODLC_00229 1.13e-102 rppH3 - - F - - - NUDIX domain
HBCFODLC_00230 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
HBCFODLC_00231 1.61e-36 - - - - - - - -
HBCFODLC_00232 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
HBCFODLC_00233 1.77e-162 gpm2 - - G - - - Phosphoglycerate mutase family
HBCFODLC_00234 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HBCFODLC_00235 8.75e-229 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HBCFODLC_00236 2.63e-204 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HBCFODLC_00237 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_00238 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_00239 6.63e-147 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HBCFODLC_00240 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HBCFODLC_00241 4.54e-54 - - - - - - - -
HBCFODLC_00243 8.83e-317 - - - EGP - - - Major Facilitator
HBCFODLC_00244 6.82e-217 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HBCFODLC_00245 4.26e-109 cvpA - - S - - - Colicin V production protein
HBCFODLC_00246 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HBCFODLC_00247 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HBCFODLC_00248 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HBCFODLC_00249 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HBCFODLC_00250 4.4e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HBCFODLC_00251 4.79e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HBCFODLC_00252 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HBCFODLC_00254 2.77e-30 - - - - - - - -
HBCFODLC_00256 1.63e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
HBCFODLC_00257 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HBCFODLC_00258 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HBCFODLC_00259 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HBCFODLC_00260 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HBCFODLC_00261 1.02e-78 qacC - - P ko:K03297,ko:K11741,ko:K11815 - ko00000,ko00002,ko02000 Multidrug Resistance protein
HBCFODLC_00262 6.1e-279 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HBCFODLC_00263 1.54e-228 ydbI - - K - - - AI-2E family transporter
HBCFODLC_00264 5.29e-212 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBCFODLC_00265 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HBCFODLC_00267 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
HBCFODLC_00268 9.7e-109 - - - - - - - -
HBCFODLC_00270 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBCFODLC_00271 2.5e-188 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HBCFODLC_00272 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HBCFODLC_00273 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBCFODLC_00274 2.6e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBCFODLC_00275 2.49e-73 - - - S - - - Enterocin A Immunity
HBCFODLC_00276 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HBCFODLC_00277 7.39e-254 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HBCFODLC_00278 1.63e-235 - - - D ko:K06889 - ko00000 Alpha beta
HBCFODLC_00279 1.04e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
HBCFODLC_00280 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
HBCFODLC_00281 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
HBCFODLC_00282 1.03e-34 - - - - - - - -
HBCFODLC_00283 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
HBCFODLC_00284 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HBCFODLC_00285 4.14e-84 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HBCFODLC_00286 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
HBCFODLC_00287 7.93e-217 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HBCFODLC_00288 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
HBCFODLC_00289 3.15e-78 - - - S - - - Enterocin A Immunity
HBCFODLC_00290 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HBCFODLC_00291 1.78e-139 - - - - - - - -
HBCFODLC_00292 8.44e-304 - - - S - - - module of peptide synthetase
HBCFODLC_00293 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
HBCFODLC_00295 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HBCFODLC_00296 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_00297 3.9e-202 - - - GM - - - NmrA-like family
HBCFODLC_00298 3.75e-103 - - - K - - - MerR family regulatory protein
HBCFODLC_00299 3.03e-191 - - - S - - - haloacid dehalogenase-like hydrolase
HBCFODLC_00300 6.9e-197 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HBCFODLC_00301 3.91e-211 - - - K - - - LysR substrate binding domain
HBCFODLC_00302 1.1e-297 - - - - - - - -
HBCFODLC_00303 2.01e-307 - - - S - - - Neutral/alkaline non-lysosomal ceramidase, N-terminal
HBCFODLC_00304 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_00305 4.17e-263 - 4.1.1.45 - E ko:K03392,ko:K07045 ko00380,ko01100,map00380,map01100 ko00000,ko00001,ko00002,ko01000 amidohydrolase
HBCFODLC_00306 6.26e-101 - - - - - - - -
HBCFODLC_00307 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBCFODLC_00308 1.76e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_00309 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HBCFODLC_00310 3.73e-263 - - - S - - - DUF218 domain
HBCFODLC_00311 1.57e-234 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HBCFODLC_00312 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HBCFODLC_00313 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_00314 4.3e-205 - - - S - - - Putative adhesin
HBCFODLC_00315 2.1e-133 - - - S - - - Protein of unknown function (DUF1700)
HBCFODLC_00316 8.52e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
HBCFODLC_00317 1.07e-127 - - - KT - - - response to antibiotic
HBCFODLC_00318 1.2e-175 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HBCFODLC_00319 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_00320 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_00321 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HBCFODLC_00322 2.07e-302 - - - EK - - - Aminotransferase, class I
HBCFODLC_00323 3.36e-216 - - - K - - - LysR substrate binding domain
HBCFODLC_00324 5.43e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HBCFODLC_00325 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
HBCFODLC_00326 5.42e-170 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HBCFODLC_00327 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HBCFODLC_00328 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HBCFODLC_00329 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HBCFODLC_00330 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HBCFODLC_00331 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HBCFODLC_00332 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
HBCFODLC_00333 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HBCFODLC_00334 2.83e-209 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HBCFODLC_00335 1.02e-162 - - - S - - - Protein of unknown function (DUF1275)
HBCFODLC_00336 1.14e-159 vanR - - K - - - response regulator
HBCFODLC_00337 5.61e-273 hpk31 - - T - - - Histidine kinase
HBCFODLC_00338 5.36e-305 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HBCFODLC_00339 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HBCFODLC_00340 2.05e-167 - - - E - - - branched-chain amino acid
HBCFODLC_00341 5.93e-73 - - - S - - - branched-chain amino acid
HBCFODLC_00342 9.65e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
HBCFODLC_00343 1.49e-72 - - - - - - - -
HBCFODLC_00344 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
HBCFODLC_00345 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
HBCFODLC_00346 5.03e-37 - - - S - - - Protein of unknown function (DUF4064)
HBCFODLC_00347 3.5e-261 pkn2 - - KLT - - - Protein tyrosine kinase
HBCFODLC_00348 2.09e-213 - - - - - - - -
HBCFODLC_00349 4.45e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HBCFODLC_00350 5.21e-151 - - - - - - - -
HBCFODLC_00351 9.28e-271 xylR - - GK - - - ROK family
HBCFODLC_00352 1.6e-233 ydbI - - K - - - AI-2E family transporter
HBCFODLC_00353 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBCFODLC_00354 6.79e-53 - - - - - - - -
HBCFODLC_00356 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
HBCFODLC_00357 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
HBCFODLC_00358 7.9e-136 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_00359 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
HBCFODLC_00360 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
HBCFODLC_00361 1.6e-103 - - - GM - - - SnoaL-like domain
HBCFODLC_00362 2.85e-141 - - - GM - - - NAD(P)H-binding
HBCFODLC_00363 4.71e-47 - - - S - - - aldo-keto reductase (NADP) activity
HBCFODLC_00364 2.31e-132 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HBCFODLC_00365 5.68e-155 yciB - - M - - - ErfK YbiS YcfS YnhG
HBCFODLC_00366 5.04e-92 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBCFODLC_00367 3.2e-109 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBCFODLC_00369 9.49e-262 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HBCFODLC_00370 1.68e-121 - - - C - - - Alcohol dehydrogenase GroES-like domain
HBCFODLC_00371 8.95e-53 - - - C - - - Alcohol dehydrogenase GroES-like domain
HBCFODLC_00372 1.4e-57 - - - K - - - HxlR-like helix-turn-helix
HBCFODLC_00373 5.57e-141 yoaZ - - S - - - intracellular protease amidase
HBCFODLC_00374 7.29e-60 - - - S - - - Protein of unknown function (DUF3781)
HBCFODLC_00375 2.73e-284 - - - S - - - Membrane
HBCFODLC_00376 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HBCFODLC_00377 2.61e-64 sgaB 2.7.1.194, 2.7.1.200 - G ko:K02774,ko:K02822,ko:K03475 ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBCFODLC_00378 1.43e-307 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HBCFODLC_00379 0.0 - 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBCFODLC_00380 3.21e-87 - - - S - - - Protein of unknown function (DUF1093)
HBCFODLC_00381 0.0 - - - G ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757 ko00010,ko02060,map00010,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_00382 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_00383 9e-190 licT2 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HBCFODLC_00385 1.85e-41 - - - - - - - -
HBCFODLC_00386 0.0 - - - L ko:K07487 - ko00000 Transposase
HBCFODLC_00387 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
HBCFODLC_00388 1.2e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBCFODLC_00389 9.89e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBCFODLC_00390 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HBCFODLC_00391 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
HBCFODLC_00392 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
HBCFODLC_00393 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
HBCFODLC_00394 2.09e-83 - - - - - - - -
HBCFODLC_00395 2.63e-200 estA - - S - - - Putative esterase
HBCFODLC_00396 5.44e-174 - - - K - - - UTRA domain
HBCFODLC_00397 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_00398 3.06e-212 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HBCFODLC_00399 1.58e-207 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HBCFODLC_00400 1.94e-270 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HBCFODLC_00401 3.55e-160 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
HBCFODLC_00402 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HBCFODLC_00403 8.58e-94 yueI - - S - - - Protein of unknown function (DUF1694)
HBCFODLC_00404 6.83e-133 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HBCFODLC_00405 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HBCFODLC_00406 1.06e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HBCFODLC_00407 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
HBCFODLC_00408 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBCFODLC_00409 1.2e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
HBCFODLC_00410 3.76e-180 - - - K - - - Helix-turn-helix domain, rpiR family
HBCFODLC_00411 6.47e-95 - - - S - - - Protein of unknown function (DUF1694)
HBCFODLC_00412 3.1e-211 - - - I - - - alpha/beta hydrolase fold
HBCFODLC_00413 2.44e-208 - - - I - - - alpha/beta hydrolase fold
HBCFODLC_00414 0.0 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBCFODLC_00415 4.01e-263 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HBCFODLC_00416 3.83e-174 - - - G - - - Xylose isomerase domain protein TIM barrel
HBCFODLC_00417 2.93e-200 nanK - - GK - - - ROK family
HBCFODLC_00418 1.86e-210 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HBCFODLC_00419 1.56e-78 - - - L - - - Transposase DDE domain
HBCFODLC_00420 3.73e-99 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
HBCFODLC_00421 1.82e-160 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HBCFODLC_00422 7.11e-295 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
HBCFODLC_00423 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
HBCFODLC_00424 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
HBCFODLC_00425 1.76e-15 - - - - - - - -
HBCFODLC_00426 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
HBCFODLC_00427 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
HBCFODLC_00428 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
HBCFODLC_00429 1.28e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HBCFODLC_00430 7.01e-286 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HBCFODLC_00431 3.82e-24 - - - - - - - -
HBCFODLC_00432 2.49e-126 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HBCFODLC_00433 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
HBCFODLC_00435 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HBCFODLC_00436 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HBCFODLC_00437 5.03e-95 - - - K - - - Transcriptional regulator
HBCFODLC_00438 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HBCFODLC_00439 4.04e-94 yueI - - S - - - Protein of unknown function (DUF1694)
HBCFODLC_00440 3.55e-163 - - - S - - - Membrane
HBCFODLC_00441 1.31e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HBCFODLC_00442 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
HBCFODLC_00443 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HBCFODLC_00444 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HBCFODLC_00445 4.04e-315 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HBCFODLC_00446 1.44e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
HBCFODLC_00447 1.28e-180 - - - K - - - DeoR C terminal sensor domain
HBCFODLC_00448 3.71e-105 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HBCFODLC_00449 2.47e-68 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HBCFODLC_00450 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HBCFODLC_00452 4.32e-174 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
HBCFODLC_00453 0.0 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBCFODLC_00454 8.65e-254 iolG2 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HBCFODLC_00455 2.4e-258 iolG 1.1.1.18, 1.1.1.369 - C ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HBCFODLC_00456 3.39e-226 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HBCFODLC_00457 2.29e-252 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HBCFODLC_00458 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBCFODLC_00459 1.87e-246 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HBCFODLC_00460 7.45e-108 - - - S - - - Haem-degrading
HBCFODLC_00461 9.67e-222 - - - C - - - Alcohol dehydrogenase GroES-like domain
HBCFODLC_00462 1.44e-228 - - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HBCFODLC_00463 4.27e-155 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
HBCFODLC_00464 5.31e-82 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HBCFODLC_00465 3.8e-228 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
HBCFODLC_00466 1.88e-131 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HBCFODLC_00467 4.71e-119 srlM1 - - K - - - Glucitol operon activator protein (GutM)
HBCFODLC_00468 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HBCFODLC_00469 5.18e-186 srlD 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HBCFODLC_00470 6.39e-235 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HBCFODLC_00471 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HBCFODLC_00472 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HBCFODLC_00473 0.0 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_00474 2.95e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HBCFODLC_00475 0.0 - 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
HBCFODLC_00476 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
HBCFODLC_00477 1.95e-250 - - - K - - - Transcriptional regulator
HBCFODLC_00478 0.0 ypdD - - G - - - Glycosyl hydrolase family 92
HBCFODLC_00479 1.09e-275 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HBCFODLC_00480 4.58e-213 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HBCFODLC_00481 0.0 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HBCFODLC_00482 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HBCFODLC_00483 1.71e-139 ypcB - - S - - - integral membrane protein
HBCFODLC_00484 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
HBCFODLC_00485 0.0 ypcG - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Domain of unknown function (DUF3502)
HBCFODLC_00486 6.47e-213 lplC - - U ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HBCFODLC_00487 1.29e-231 ypdA - - U ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HBCFODLC_00488 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
HBCFODLC_00489 1.64e-200 - - - K - - - helix_turn_helix, arabinose operon control protein
HBCFODLC_00490 0.0 mdlA2 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HBCFODLC_00491 0.0 yknV - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_00492 2.99e-247 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HBCFODLC_00493 1.99e-203 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HBCFODLC_00494 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HBCFODLC_00495 2.5e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
HBCFODLC_00496 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HBCFODLC_00497 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
HBCFODLC_00498 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HBCFODLC_00499 1.56e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HBCFODLC_00500 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
HBCFODLC_00501 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HBCFODLC_00502 3.87e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBCFODLC_00503 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HBCFODLC_00504 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HBCFODLC_00505 2.51e-103 - - - T - - - Universal stress protein family
HBCFODLC_00506 7.43e-130 padR - - K - - - Virulence activator alpha C-term
HBCFODLC_00507 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HBCFODLC_00508 6.11e-187 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HBCFODLC_00509 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
HBCFODLC_00510 6.95e-204 degV1 - - S - - - DegV family
HBCFODLC_00511 1.43e-80 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
HBCFODLC_00512 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HBCFODLC_00514 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HBCFODLC_00515 0.0 - - - - - - - -
HBCFODLC_00517 1.1e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
HBCFODLC_00518 3.21e-144 - - - S - - - Cell surface protein
HBCFODLC_00519 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HBCFODLC_00520 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HBCFODLC_00521 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
HBCFODLC_00522 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HBCFODLC_00523 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HBCFODLC_00524 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBCFODLC_00525 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HBCFODLC_00526 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HBCFODLC_00527 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HBCFODLC_00528 1.75e-47 - - - K - - - MerR HTH family regulatory protein
HBCFODLC_00529 1.43e-155 azlC - - E - - - branched-chain amino acid
HBCFODLC_00530 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HBCFODLC_00531 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HBCFODLC_00532 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HBCFODLC_00533 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBCFODLC_00534 0.0 xylP2 - - G - - - symporter
HBCFODLC_00535 7.32e-247 - - - I - - - alpha/beta hydrolase fold
HBCFODLC_00536 3.33e-64 - - - - - - - -
HBCFODLC_00537 6.39e-158 gpm5 - - G - - - Phosphoglycerate mutase family
HBCFODLC_00538 1.22e-132 - - - K - - - FR47-like protein
HBCFODLC_00539 4.18e-163 yibF - - S - - - overlaps another CDS with the same product name
HBCFODLC_00540 1.46e-281 yibE - - S - - - overlaps another CDS with the same product name
HBCFODLC_00541 1.94e-244 - - - - - - - -
HBCFODLC_00542 5.03e-180 - - - S - - - NADPH-dependent FMN reductase
HBCFODLC_00543 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HBCFODLC_00544 3.62e-213 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HBCFODLC_00545 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HBCFODLC_00546 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
HBCFODLC_00547 5.44e-56 - - - - - - - -
HBCFODLC_00548 3.24e-291 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBCFODLC_00549 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HBCFODLC_00550 1.38e-254 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HBCFODLC_00551 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HBCFODLC_00552 3.45e-151 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBCFODLC_00553 4.3e-106 - - - K - - - Transcriptional regulator
HBCFODLC_00555 0.0 - - - C - - - FMN_bind
HBCFODLC_00556 1.37e-220 - - - K - - - Transcriptional regulator
HBCFODLC_00557 6.57e-125 - - - K - - - Helix-turn-helix domain
HBCFODLC_00558 1.83e-180 - - - K - - - sequence-specific DNA binding
HBCFODLC_00559 8.92e-116 - - - S - - - AAA domain
HBCFODLC_00560 1.42e-08 - - - - - - - -
HBCFODLC_00561 0.0 - - - M - - - MucBP domain
HBCFODLC_00562 1.83e-123 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
HBCFODLC_00563 8.31e-225 - - - L - - - Belongs to the 'phage' integrase family
HBCFODLC_00564 7.71e-277 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HBCFODLC_00565 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HBCFODLC_00566 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HBCFODLC_00567 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HBCFODLC_00568 1.22e-137 - - - G - - - Glycogen debranching enzyme
HBCFODLC_00569 2.3e-65 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HBCFODLC_00570 1.54e-217 yjdB - - S - - - Domain of unknown function (DUF4767)
HBCFODLC_00571 1.22e-193 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
HBCFODLC_00572 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
HBCFODLC_00573 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
HBCFODLC_00574 5.74e-32 - - - - - - - -
HBCFODLC_00575 1.95e-116 - - - - - - - -
HBCFODLC_00576 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
HBCFODLC_00577 0.0 XK27_09800 - - I - - - Acyltransferase family
HBCFODLC_00578 3.61e-61 - - - S - - - MORN repeat
HBCFODLC_00579 0.0 - - - S - - - Cysteine-rich secretory protein family
HBCFODLC_00580 4.73e-302 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
HBCFODLC_00581 1.85e-75 - - - K - - - HxlR-like helix-turn-helix
HBCFODLC_00582 2.01e-149 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_00583 0.0 - - - L - - - AAA domain
HBCFODLC_00584 1.37e-83 - - - K - - - Helix-turn-helix domain
HBCFODLC_00585 1.08e-71 - - - - - - - -
HBCFODLC_00586 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HBCFODLC_00587 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HBCFODLC_00588 8.82e-213 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HBCFODLC_00589 2.1e-270 - - - - - - - -
HBCFODLC_00590 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
HBCFODLC_00591 1.94e-83 - - - P - - - Rhodanese Homology Domain
HBCFODLC_00592 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HBCFODLC_00593 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HBCFODLC_00594 3.08e-215 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_00595 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HBCFODLC_00596 1.75e-295 - - - M - - - O-Antigen ligase
HBCFODLC_00597 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HBCFODLC_00598 1.61e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBCFODLC_00599 3.17e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HBCFODLC_00600 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HBCFODLC_00601 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
HBCFODLC_00602 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HBCFODLC_00603 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HBCFODLC_00604 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HBCFODLC_00605 1.03e-55 - - - - - - - -
HBCFODLC_00606 6.89e-37 - - - - - - - -
HBCFODLC_00607 0.0 traA - - L - - - MobA MobL family protein
HBCFODLC_00608 2.7e-69 - - - - - - - -
HBCFODLC_00609 4.34e-138 - - - - - - - -
HBCFODLC_00610 5.4e-69 - - - S - - - Cag pathogenicity island, type IV secretory system
HBCFODLC_00611 9.31e-72 - - - - - - - -
HBCFODLC_00612 3.29e-154 - - - - - - - -
HBCFODLC_00613 0.0 traE - - U - - - AAA-like domain
HBCFODLC_00614 0.0 - - - S - - - WXG100 protein secretion system (Wss), protein YukC
HBCFODLC_00615 1.03e-283 - - - M - - - CHAP domain
HBCFODLC_00616 2.45e-124 - - - - - - - -
HBCFODLC_00617 3.35e-84 - - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HBCFODLC_00618 2.4e-107 - - - - - - - -
HBCFODLC_00619 0.0 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
HBCFODLC_00620 1.25e-80 - - - - - - - -
HBCFODLC_00621 1.02e-199 - - - - - - - -
HBCFODLC_00622 1.35e-92 - - - - - - - -
HBCFODLC_00623 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HBCFODLC_00624 7.81e-46 - - - - - - - -
HBCFODLC_00625 2.53e-30 - - - L - - - nucleotidyltransferase activity
HBCFODLC_00626 1.74e-250 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
HBCFODLC_00627 2.7e-132 cadD - - P - - - Cadmium resistance transporter
HBCFODLC_00628 4.58e-82 - - - K - - - Transcriptional regulator
HBCFODLC_00629 0.0 nox 1.11.1.1 - P ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HBCFODLC_00630 2.15e-67 - - - S - - - Arsenical resistance operon trans-acting repressor ArsD
HBCFODLC_00631 5.45e-68 - - - - - - - -
HBCFODLC_00632 1.1e-295 arsB - - U ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBCFODLC_00633 0.0 arsA 3.6.3.16 - D ko:K01551 - ko00000,ko01000,ko02000 Anion-transporting ATPase
HBCFODLC_00634 1.38e-82 - - - S - - - Arsenical resistance operon trans-acting repressor ArsD
HBCFODLC_00635 5.62e-86 - - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HBCFODLC_00636 2.47e-125 tnpR1 - - L - - - Resolvase, N terminal domain
HBCFODLC_00637 2.03e-31 - - - S - - - Family of unknown function (DUF5388)
HBCFODLC_00638 5.86e-185 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HBCFODLC_00640 1.78e-67 repA - - S - - - Replication initiator protein A
HBCFODLC_00641 6.94e-59 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
HBCFODLC_00642 0.0 - - - L - - - Domain of unknown function (DUF4158)
HBCFODLC_00643 4.36e-129 tnpR2 - - L - - - Helix-turn-helix domain of resolvase
HBCFODLC_00645 2.41e-156 - - - S - - - Plasmid replication protein
HBCFODLC_00647 6.14e-122 - - - - - - - -
HBCFODLC_00648 3.73e-111 - - - - - - - -
HBCFODLC_00649 8.96e-91 rusA - - L - - - Endodeoxyribonuclease RusA
HBCFODLC_00655 3.06e-79 - - - S - - - YopX protein
HBCFODLC_00656 2.44e-17 - - - - - - - -
HBCFODLC_00657 7.97e-30 - - - - - - - -
HBCFODLC_00658 5.27e-107 - - - S - - - Phage transcriptional regulator, ArpU family
HBCFODLC_00661 7.73e-23 - - - - - - - -
HBCFODLC_00663 9.87e-132 - - - L ko:K07474 - ko00000 Terminase small subunit
HBCFODLC_00664 0.0 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
HBCFODLC_00665 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HBCFODLC_00666 2.13e-227 - - - S - - - Phage Mu protein F like protein
HBCFODLC_00667 1.14e-111 - - - S - - - Domain of unknown function (DUF4355)
HBCFODLC_00668 1.9e-258 gpG - - - - - - -
HBCFODLC_00669 1.8e-83 - - - S - - - Phage gp6-like head-tail connector protein
HBCFODLC_00670 7.48e-74 - - - - - - - -
HBCFODLC_00671 2.57e-127 - - - - - - - -
HBCFODLC_00672 1.9e-86 - - - - - - - -
HBCFODLC_00673 1.79e-137 - - - - - - - -
HBCFODLC_00674 1.41e-115 - - - S - - - Phage tail assembly chaperone protein, TAC
HBCFODLC_00676 0.0 - - - D - - - domain protein
HBCFODLC_00677 1.19e-182 - - - S - - - phage tail
HBCFODLC_00678 0.0 - - - M - - - Prophage endopeptidase tail
HBCFODLC_00679 3.46e-241 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HBCFODLC_00680 1.92e-141 - - - S - - - Domain of unknown function (DUF2479)
HBCFODLC_00683 2.56e-34 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
HBCFODLC_00684 3.28e-279 - - - M - - - hydrolase, family 25
HBCFODLC_00685 5.53e-65 - - - - - - - -
HBCFODLC_00686 1.96e-68 hol - - S - - - COG5546 Small integral membrane protein
HBCFODLC_00689 7.12e-280 - - - - - - - -
HBCFODLC_00690 1.5e-228 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HBCFODLC_00691 1.78e-88 - - - L - - - nuclease
HBCFODLC_00692 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBCFODLC_00693 5.82e-141 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HBCFODLC_00694 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBCFODLC_00695 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBCFODLC_00696 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HBCFODLC_00697 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HBCFODLC_00698 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HBCFODLC_00699 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBCFODLC_00700 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HBCFODLC_00701 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HBCFODLC_00702 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
HBCFODLC_00703 2.22e-153 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HBCFODLC_00704 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
HBCFODLC_00705 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HBCFODLC_00706 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
HBCFODLC_00707 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HBCFODLC_00708 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HBCFODLC_00709 4.95e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HBCFODLC_00710 9.25e-271 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HBCFODLC_00711 1.39e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
HBCFODLC_00712 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_00713 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
HBCFODLC_00714 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HBCFODLC_00715 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HBCFODLC_00716 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HBCFODLC_00717 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HBCFODLC_00718 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HBCFODLC_00719 7.63e-251 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HBCFODLC_00720 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HBCFODLC_00721 3.04e-280 ylbM - - S - - - Belongs to the UPF0348 family
HBCFODLC_00722 3.3e-180 yqeM - - Q - - - Methyltransferase
HBCFODLC_00723 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HBCFODLC_00724 1.71e-149 yqeK - - H - - - Hydrolase, HD family
HBCFODLC_00725 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HBCFODLC_00726 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HBCFODLC_00727 1.33e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HBCFODLC_00728 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HBCFODLC_00729 6.32e-114 - - - - - - - -
HBCFODLC_00730 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HBCFODLC_00731 2.39e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HBCFODLC_00732 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
HBCFODLC_00733 5.21e-254 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HBCFODLC_00734 6.02e-308 - - - L ko:K07478 - ko00000 AAA C-terminal domain
HBCFODLC_00735 2.76e-74 - - - - - - - -
HBCFODLC_00736 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HBCFODLC_00737 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HBCFODLC_00738 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HBCFODLC_00739 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBCFODLC_00740 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HBCFODLC_00741 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HBCFODLC_00742 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HBCFODLC_00743 9.54e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBCFODLC_00744 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HBCFODLC_00745 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBCFODLC_00746 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HBCFODLC_00747 6.66e-39 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HBCFODLC_00748 4.4e-126 - - - S - - - Protein of unknown function (DUF2975)
HBCFODLC_00749 3.1e-97 - - - - - - - -
HBCFODLC_00750 1.1e-228 - - - - - - - -
HBCFODLC_00751 1.89e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
HBCFODLC_00752 2.1e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
HBCFODLC_00753 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HBCFODLC_00754 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBCFODLC_00755 1.27e-250 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HBCFODLC_00756 1.34e-108 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HBCFODLC_00757 1.55e-295 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
HBCFODLC_00758 2.87e-117 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HBCFODLC_00759 1.08e-111 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HBCFODLC_00760 5.73e-129 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HBCFODLC_00761 8.84e-52 - - - - - - - -
HBCFODLC_00762 1.48e-98 - 2.7.13.3 - T ko:K07683,ko:K10851 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 phosphoenolpyruvate-protein phosphotransferase activity
HBCFODLC_00763 1.04e-244 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
HBCFODLC_00764 5.46e-152 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HBCFODLC_00765 3.67e-65 - - - - - - - -
HBCFODLC_00766 6.4e-235 - - - - - - - -
HBCFODLC_00767 2.63e-209 - - - H - - - geranyltranstransferase activity
HBCFODLC_00768 7.79e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HBCFODLC_00769 4.08e-78 - - - S - - - Iron-sulfur cluster assembly protein
HBCFODLC_00770 1.98e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
HBCFODLC_00771 3.92e-248 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBCFODLC_00772 7.86e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
HBCFODLC_00773 6.26e-92 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
HBCFODLC_00774 1.65e-107 - - - C - - - Flavodoxin
HBCFODLC_00775 1.45e-214 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBCFODLC_00776 1.14e-177 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HBCFODLC_00777 7.63e-249 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HBCFODLC_00778 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HBCFODLC_00779 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HBCFODLC_00780 4.02e-302 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBCFODLC_00781 3.14e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HBCFODLC_00782 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HBCFODLC_00783 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HBCFODLC_00784 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HBCFODLC_00785 3.04e-29 - - - S - - - Virus attachment protein p12 family
HBCFODLC_00786 1.83e-164 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HBCFODLC_00787 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HBCFODLC_00788 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
HBCFODLC_00789 2.21e-46 - - - - - - - -
HBCFODLC_00790 3.68e-197 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HBCFODLC_00791 2.03e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HBCFODLC_00792 3.74e-136 - - - GM - - - NAD(P)H-binding
HBCFODLC_00793 1.15e-204 - - - K - - - LysR substrate binding domain
HBCFODLC_00794 1.49e-83 - - - S - - - Domain of unknown function (DUF4440)
HBCFODLC_00795 5.46e-145 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
HBCFODLC_00796 2.81e-64 - - - - - - - -
HBCFODLC_00797 9.76e-50 - - - - - - - -
HBCFODLC_00798 4.58e-114 yvbK - - K - - - GNAT family
HBCFODLC_00799 8.4e-112 - - - - - - - -
HBCFODLC_00800 9.91e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HBCFODLC_00801 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HBCFODLC_00802 1.91e-142 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HBCFODLC_00803 5.06e-152 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBCFODLC_00805 5.42e-47 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_00806 1.31e-89 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_00807 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HBCFODLC_00808 5.3e-302 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HBCFODLC_00809 1.27e-103 - - - K - - - transcriptional regulator, MerR family
HBCFODLC_00810 4.77e-100 yphH - - S - - - Cupin domain
HBCFODLC_00811 2e-73 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HBCFODLC_00812 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HBCFODLC_00813 6.76e-270 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HBCFODLC_00814 1.04e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_00815 3.92e-120 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HBCFODLC_00816 2.72e-90 - - - M - - - LysM domain
HBCFODLC_00817 1.14e-79 - - - M - - - LysM domain protein
HBCFODLC_00818 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HBCFODLC_00819 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HBCFODLC_00820 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HBCFODLC_00821 2.17e-222 - - - S - - - Conserved hypothetical protein 698
HBCFODLC_00822 1.33e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HBCFODLC_00823 5.97e-106 - - - S - - - Domain of unknown function (DUF4811)
HBCFODLC_00824 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HBCFODLC_00825 4.35e-164 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HBCFODLC_00826 3.04e-261 - - - EGP - - - Major Facilitator Superfamily
HBCFODLC_00827 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HBCFODLC_00828 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
HBCFODLC_00829 5.21e-154 - - - S - - - Membrane
HBCFODLC_00830 1.39e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HBCFODLC_00831 3.55e-127 ywjB - - H - - - RibD C-terminal domain
HBCFODLC_00832 1.46e-240 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HBCFODLC_00833 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
HBCFODLC_00834 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_00835 3.59e-242 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HBCFODLC_00836 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HBCFODLC_00837 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBCFODLC_00838 8.38e-192 - - - KT - - - helix_turn_helix, mercury resistance
HBCFODLC_00839 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HBCFODLC_00841 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
HBCFODLC_00842 3.84e-185 - - - S - - - Peptidase_C39 like family
HBCFODLC_00843 2.05e-248 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HBCFODLC_00844 1.54e-144 - - - - - - - -
HBCFODLC_00845 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBCFODLC_00846 1.97e-110 - - - S - - - Pfam:DUF3816
HBCFODLC_00847 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HBCFODLC_00848 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
HBCFODLC_00849 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
HBCFODLC_00850 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HBCFODLC_00851 0.0 nox - - C - - - NADH oxidase
HBCFODLC_00852 9.43e-162 - - - T - - - Putative diguanylate phosphodiesterase
HBCFODLC_00853 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HBCFODLC_00854 1.2e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HBCFODLC_00855 6.26e-213 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HBCFODLC_00856 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HBCFODLC_00857 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HBCFODLC_00858 3.38e-66 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HBCFODLC_00859 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HBCFODLC_00860 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HBCFODLC_00861 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HBCFODLC_00862 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HBCFODLC_00863 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HBCFODLC_00864 1.19e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HBCFODLC_00865 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HBCFODLC_00866 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HBCFODLC_00867 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HBCFODLC_00868 5.06e-259 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HBCFODLC_00869 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HBCFODLC_00870 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HBCFODLC_00871 2.94e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HBCFODLC_00872 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HBCFODLC_00873 9.07e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HBCFODLC_00874 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HBCFODLC_00875 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HBCFODLC_00876 0.0 ydaO - - E - - - amino acid
HBCFODLC_00877 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HBCFODLC_00878 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HBCFODLC_00879 1.68e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_00880 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HBCFODLC_00881 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HBCFODLC_00882 3.36e-88 - - - K - - - HxlR-like helix-turn-helix
HBCFODLC_00883 3.88e-203 - - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HBCFODLC_00884 2.5e-282 - - - C - - - Oxidoreductase
HBCFODLC_00885 2.56e-95 - - - S - - - macrophage migration inhibitory factor
HBCFODLC_00886 1.86e-208 - - - I - - - carboxylic ester hydrolase activity
HBCFODLC_00887 5.25e-258 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBCFODLC_00888 4.85e-207 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HBCFODLC_00889 5.71e-152 - - - GM - - - NAD(P)H-binding
HBCFODLC_00890 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
HBCFODLC_00891 2.95e-199 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBCFODLC_00892 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
HBCFODLC_00893 7.5e-202 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_00894 3.63e-164 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HBCFODLC_00896 0.0 XK27_06930 - - V ko:K01421 - ko00000 domain protein
HBCFODLC_00897 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HBCFODLC_00898 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
HBCFODLC_00899 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HBCFODLC_00900 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HBCFODLC_00901 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_00902 3.93e-222 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HBCFODLC_00903 1.24e-259 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HBCFODLC_00904 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
HBCFODLC_00905 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HBCFODLC_00906 7.77e-196 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBCFODLC_00907 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HBCFODLC_00908 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HBCFODLC_00909 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HBCFODLC_00910 6.19e-162 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HBCFODLC_00911 5.13e-138 mraW1 - - J - - - Putative rRNA methylase
HBCFODLC_00912 9.32e-40 - - - - - - - -
HBCFODLC_00913 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HBCFODLC_00914 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HBCFODLC_00915 0.0 - - - S - - - Pfam Methyltransferase
HBCFODLC_00916 6.56e-22 - - - N - - - Cell shape-determining protein MreB
HBCFODLC_00918 9.81e-27 - - - - - - - -
HBCFODLC_00919 4.04e-125 - - - K - - - Transcriptional regulator
HBCFODLC_00920 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HBCFODLC_00921 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HBCFODLC_00922 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HBCFODLC_00923 1.48e-249 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HBCFODLC_00924 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HBCFODLC_00925 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HBCFODLC_00926 4.86e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HBCFODLC_00927 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HBCFODLC_00928 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBCFODLC_00929 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBCFODLC_00930 6.68e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HBCFODLC_00931 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HBCFODLC_00932 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HBCFODLC_00933 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HBCFODLC_00934 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_00935 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_00936 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HBCFODLC_00937 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HBCFODLC_00938 3.51e-74 - - - - - - - -
HBCFODLC_00939 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HBCFODLC_00940 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HBCFODLC_00941 1.24e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBCFODLC_00942 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBCFODLC_00943 5.2e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HBCFODLC_00944 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HBCFODLC_00945 9.75e-175 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HBCFODLC_00946 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HBCFODLC_00947 2.96e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HBCFODLC_00948 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HBCFODLC_00949 1.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HBCFODLC_00950 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HBCFODLC_00951 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
HBCFODLC_00952 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HBCFODLC_00953 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBCFODLC_00954 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HBCFODLC_00955 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBCFODLC_00956 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HBCFODLC_00957 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HBCFODLC_00958 2.94e-309 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HBCFODLC_00959 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HBCFODLC_00960 9.38e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBCFODLC_00961 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HBCFODLC_00962 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HBCFODLC_00963 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBCFODLC_00964 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HBCFODLC_00965 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HBCFODLC_00966 4.72e-72 - - - - - - - -
HBCFODLC_00967 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HBCFODLC_00968 1.1e-112 - - - - - - - -
HBCFODLC_00969 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HBCFODLC_00970 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
HBCFODLC_00972 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
HBCFODLC_00973 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
HBCFODLC_00974 1.04e-226 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBCFODLC_00975 2.52e-167 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HBCFODLC_00976 1.57e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HBCFODLC_00977 3.93e-291 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HBCFODLC_00978 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HBCFODLC_00979 1.02e-126 entB - - Q - - - Isochorismatase family
HBCFODLC_00980 5.45e-231 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
HBCFODLC_00981 1.69e-94 ybbJ - - K - - - Acetyltransferase (GNAT) family
HBCFODLC_00982 4.84e-278 - - - E - - - glutamate:sodium symporter activity
HBCFODLC_00983 3.38e-274 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
HBCFODLC_00984 8.04e-254 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HBCFODLC_00985 1.09e-79 - - - S - - - Protein of unknown function (DUF1648)
HBCFODLC_00986 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HBCFODLC_00987 8.02e-230 yneE - - K - - - Transcriptional regulator
HBCFODLC_00988 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HBCFODLC_00989 9.77e-231 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBCFODLC_00990 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBCFODLC_00991 8.89e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HBCFODLC_00992 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HBCFODLC_00993 5.38e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HBCFODLC_00994 5.25e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HBCFODLC_00995 7.23e-93 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HBCFODLC_00996 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HBCFODLC_00997 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HBCFODLC_00998 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HBCFODLC_00999 2.29e-175 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HBCFODLC_01000 1.5e-130 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HBCFODLC_01001 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HBCFODLC_01002 3.73e-207 - - - K - - - LysR substrate binding domain
HBCFODLC_01003 8.53e-115 ykhA - - I - - - Thioesterase superfamily
HBCFODLC_01004 6.52e-248 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HBCFODLC_01005 1.49e-121 - - - K - - - transcriptional regulator
HBCFODLC_01006 0.0 - - - EGP - - - Major Facilitator
HBCFODLC_01007 1.14e-193 - - - O - - - Band 7 protein
HBCFODLC_01008 1.73e-113 - - - S - - - Protein of unknown function with HXXEE motif
HBCFODLC_01010 2.91e-176 - - - K - - - helix_turn_helix, arabinose operon control protein
HBCFODLC_01011 8.77e-192 cps3J - - M - - - Domain of unknown function (DUF4422)
HBCFODLC_01012 5.06e-260 cps3I - - G - - - Acyltransferase family
HBCFODLC_01013 1.03e-264 cps3H - - - - - - -
HBCFODLC_01014 1.73e-207 cps3F - - - - - - -
HBCFODLC_01015 3.55e-146 cps3E - - - - - - -
HBCFODLC_01016 2.88e-262 cps3D - - - - - - -
HBCFODLC_01017 7.21e-285 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HBCFODLC_01018 8.04e-230 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HBCFODLC_01019 9.7e-223 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HBCFODLC_01020 2.03e-162 - - - L - - - Helix-turn-helix domain
HBCFODLC_01021 1.8e-165 - - - L ko:K07497 - ko00000 hmm pf00665
HBCFODLC_01023 5.93e-163 CP_1020 - - S - - - zinc ion binding
HBCFODLC_01024 2.87e-39 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
HBCFODLC_01025 3.35e-151 - - - M - - - Glycosyl transferases group 1
HBCFODLC_01026 1.14e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
HBCFODLC_01027 2.19e-131 - - - L - - - Helix-turn-helix domain
HBCFODLC_01028 1.89e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
HBCFODLC_01029 3.82e-184 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HBCFODLC_01030 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HBCFODLC_01031 8.31e-295 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
HBCFODLC_01033 1.75e-43 - - - - - - - -
HBCFODLC_01034 5.27e-186 - - - Q - - - Methyltransferase
HBCFODLC_01035 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
HBCFODLC_01036 2.87e-270 - - - EGP - - - Major facilitator Superfamily
HBCFODLC_01037 7.9e-136 - - - K - - - Helix-turn-helix domain
HBCFODLC_01038 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HBCFODLC_01039 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HBCFODLC_01040 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
HBCFODLC_01041 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HBCFODLC_01042 2.05e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HBCFODLC_01043 6.62e-62 - - - - - - - -
HBCFODLC_01044 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HBCFODLC_01045 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HBCFODLC_01046 7.34e-219 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HBCFODLC_01047 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HBCFODLC_01048 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HBCFODLC_01049 0.0 cps4J - - S - - - MatE
HBCFODLC_01050 2.05e-229 cps4I - - M - - - Glycosyltransferase like family 2
HBCFODLC_01051 8.1e-299 - - - - - - - -
HBCFODLC_01052 1.94e-244 cps4G - - M - - - Glycosyltransferase Family 4
HBCFODLC_01053 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
HBCFODLC_01054 5.71e-165 tuaA - - M - - - Bacterial sugar transferase
HBCFODLC_01055 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HBCFODLC_01056 1.93e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HBCFODLC_01057 3e-158 ywqD - - D - - - Capsular exopolysaccharide family
HBCFODLC_01058 3.75e-165 epsB - - M - - - biosynthesis protein
HBCFODLC_01059 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HBCFODLC_01060 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_01061 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HBCFODLC_01062 5.12e-31 - - - - - - - -
HBCFODLC_01063 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
HBCFODLC_01064 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
HBCFODLC_01065 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HBCFODLC_01066 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HBCFODLC_01067 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HBCFODLC_01068 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HBCFODLC_01069 1.24e-205 - - - S - - - Tetratricopeptide repeat
HBCFODLC_01070 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBCFODLC_01071 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBCFODLC_01072 9.44e-263 - - - EGP - - - Major Facilitator Superfamily
HBCFODLC_01073 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HBCFODLC_01074 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HBCFODLC_01075 5.09e-241 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HBCFODLC_01076 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HBCFODLC_01077 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HBCFODLC_01078 1.91e-157 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HBCFODLC_01079 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HBCFODLC_01080 2.56e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HBCFODLC_01081 2.11e-132 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HBCFODLC_01082 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HBCFODLC_01083 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HBCFODLC_01084 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HBCFODLC_01085 0.0 - - - - - - - -
HBCFODLC_01086 0.0 icaA - - M - - - Glycosyl transferase family group 2
HBCFODLC_01087 1.41e-136 - - - - - - - -
HBCFODLC_01088 9.43e-259 - - - - - - - -
HBCFODLC_01089 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HBCFODLC_01090 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HBCFODLC_01091 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
HBCFODLC_01092 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
HBCFODLC_01093 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HBCFODLC_01094 5e-292 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HBCFODLC_01095 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HBCFODLC_01096 2.98e-269 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HBCFODLC_01097 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HBCFODLC_01098 6.45e-111 - - - - - - - -
HBCFODLC_01099 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
HBCFODLC_01100 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBCFODLC_01101 1.03e-241 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HBCFODLC_01102 2.16e-39 - - - - - - - -
HBCFODLC_01103 6.99e-171 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HBCFODLC_01104 0.0 - - - - - - - -
HBCFODLC_01105 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HBCFODLC_01106 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HBCFODLC_01107 1.22e-218 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HBCFODLC_01108 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HBCFODLC_01109 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HBCFODLC_01110 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HBCFODLC_01111 1.13e-257 yueF - - S - - - AI-2E family transporter
HBCFODLC_01112 7.3e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HBCFODLC_01113 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
HBCFODLC_01114 3.97e-64 - - - K - - - sequence-specific DNA binding
HBCFODLC_01115 2.47e-173 lytE - - M - - - NlpC/P60 family
HBCFODLC_01116 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HBCFODLC_01117 1.49e-183 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HBCFODLC_01118 3.43e-171 - - - - - - - -
HBCFODLC_01119 4.14e-132 - - - K - - - DNA-templated transcription, initiation
HBCFODLC_01120 4.16e-38 - - - - - - - -
HBCFODLC_01121 6.78e-42 - - - - - - - -
HBCFODLC_01122 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
HBCFODLC_01123 9.02e-70 - - - - - - - -
HBCFODLC_01124 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HBCFODLC_01125 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HBCFODLC_01126 5.36e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HBCFODLC_01127 0.0 - - - M - - - domain protein
HBCFODLC_01128 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBCFODLC_01129 4.71e-74 - - - S - - - SdpI/YhfL protein family
HBCFODLC_01130 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
HBCFODLC_01131 3.45e-83 - - - K - - - helix_turn_helix, mercury resistance
HBCFODLC_01132 2.03e-271 yttB - - EGP - - - Major Facilitator
HBCFODLC_01133 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HBCFODLC_01134 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HBCFODLC_01135 0.0 yhdP - - S - - - Transporter associated domain
HBCFODLC_01136 2.97e-76 - - - - - - - -
HBCFODLC_01137 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HBCFODLC_01138 5.4e-80 - - - - - - - -
HBCFODLC_01139 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
HBCFODLC_01140 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
HBCFODLC_01141 5.26e-155 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HBCFODLC_01142 1.49e-179 - - - - - - - -
HBCFODLC_01143 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBCFODLC_01144 3.53e-169 - - - K - - - Transcriptional regulator
HBCFODLC_01145 6.26e-213 - - - S - - - Putative esterase
HBCFODLC_01146 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HBCFODLC_01147 1.85e-285 - - - M - - - Glycosyl transferases group 1
HBCFODLC_01148 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
HBCFODLC_01149 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
HBCFODLC_01150 1.84e-205 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HBCFODLC_01151 2.51e-103 uspA3 - - T - - - universal stress protein
HBCFODLC_01152 5.87e-166 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HBCFODLC_01153 1.49e-112 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HBCFODLC_01154 5.2e-185 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HBCFODLC_01155 3.82e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HBCFODLC_01156 1.63e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HBCFODLC_01157 5.63e-225 - - - K - - - Transcriptional regulator, LysR family
HBCFODLC_01158 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBCFODLC_01159 1.61e-175 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HBCFODLC_01160 1.83e-230 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HBCFODLC_01161 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HBCFODLC_01162 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
HBCFODLC_01163 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HBCFODLC_01164 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HBCFODLC_01165 4.27e-253 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HBCFODLC_01166 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HBCFODLC_01167 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HBCFODLC_01168 1.64e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HBCFODLC_01169 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HBCFODLC_01170 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HBCFODLC_01171 3.1e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HBCFODLC_01172 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HBCFODLC_01173 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HBCFODLC_01174 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HBCFODLC_01175 3.9e-143 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HBCFODLC_01176 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
HBCFODLC_01177 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
HBCFODLC_01178 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HBCFODLC_01179 3.03e-295 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HBCFODLC_01180 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HBCFODLC_01181 1.65e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HBCFODLC_01182 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HBCFODLC_01183 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HBCFODLC_01184 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HBCFODLC_01185 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HBCFODLC_01186 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HBCFODLC_01187 4.03e-283 - - - S - - - associated with various cellular activities
HBCFODLC_01188 0.0 - - - S - - - Putative metallopeptidase domain
HBCFODLC_01189 1.03e-65 - - - - - - - -
HBCFODLC_01190 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
HBCFODLC_01191 2.05e-66 - - - S - - - Bacteriophage holin
HBCFODLC_01192 6.47e-64 - - - - - - - -
HBCFODLC_01193 9.17e-240 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HBCFODLC_01194 1.61e-44 - - - - - - - -
HBCFODLC_01195 9.91e-248 - - - - - - - -
HBCFODLC_01196 0.0 - - - S - - - Calcineurin-like phosphoesterase
HBCFODLC_01198 1.25e-286 - - - M - - - Prophage endopeptidase tail
HBCFODLC_01199 1.33e-222 - - - S - - - Phage tail protein
HBCFODLC_01200 0.0 - - - D - - - domain protein
HBCFODLC_01202 1.67e-110 - - - S - - - Phage tail assembly chaperone protein, TAC
HBCFODLC_01203 2.67e-131 - - - - - - - -
HBCFODLC_01204 5.66e-88 - - - - - - - -
HBCFODLC_01205 2.57e-127 - - - - - - - -
HBCFODLC_01206 6.15e-73 - - - - - - - -
HBCFODLC_01207 4.42e-84 - - - S - - - Phage gp6-like head-tail connector protein
HBCFODLC_01208 1.34e-256 gpG - - - - - - -
HBCFODLC_01209 4.64e-143 - - - S - - - Domain of unknown function (DUF4355)
HBCFODLC_01210 9.03e-229 - - - S - - - Phage Mu protein F like protein
HBCFODLC_01211 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HBCFODLC_01212 6.3e-139 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
HBCFODLC_01213 4.19e-166 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
HBCFODLC_01215 8.12e-110 - - - L ko:K07474 - ko00000 Terminase small subunit
HBCFODLC_01217 5.45e-60 - - - - - - - -
HBCFODLC_01218 6.96e-37 - - - - - - - -
HBCFODLC_01223 5.73e-60 - - - - - - - -
HBCFODLC_01224 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HBCFODLC_01225 1.11e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
HBCFODLC_01226 1.16e-209 - - - K - - - LysR substrate binding domain
HBCFODLC_01227 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HBCFODLC_01228 0.0 - - - S - - - MucBP domain
HBCFODLC_01229 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HBCFODLC_01230 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
HBCFODLC_01231 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HBCFODLC_01232 4.15e-78 - - - - - - - -
HBCFODLC_01233 4.05e-98 - - - - - - - -
HBCFODLC_01234 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
HBCFODLC_01235 3.11e-76 - - - - - - - -
HBCFODLC_01236 3.89e-62 - - - - - - - -
HBCFODLC_01237 1.16e-263 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
HBCFODLC_01238 9.89e-74 ytpP - - CO - - - Thioredoxin
HBCFODLC_01239 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
HBCFODLC_01240 3.65e-90 - - - - - - - -
HBCFODLC_01241 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HBCFODLC_01242 1.44e-65 - - - - - - - -
HBCFODLC_01243 1.28e-77 - - - - - - - -
HBCFODLC_01244 1.86e-210 - - - - - - - -
HBCFODLC_01245 1.4e-95 - - - K - - - Transcriptional regulator
HBCFODLC_01246 0.0 pepF2 - - E - - - Oligopeptidase F
HBCFODLC_01247 3.96e-224 ybcH - - D ko:K06889 - ko00000 Alpha beta
HBCFODLC_01248 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HBCFODLC_01249 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
HBCFODLC_01250 1.22e-292 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HBCFODLC_01251 1.96e-293 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HBCFODLC_01252 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBCFODLC_01253 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HBCFODLC_01254 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HBCFODLC_01255 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBCFODLC_01256 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HBCFODLC_01257 5.6e-41 - - - - - - - -
HBCFODLC_01258 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HBCFODLC_01259 2.5e-132 - - - L - - - Integrase
HBCFODLC_01260 3.4e-85 - - - K - - - Winged helix DNA-binding domain
HBCFODLC_01261 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HBCFODLC_01262 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HBCFODLC_01263 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBCFODLC_01264 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBCFODLC_01265 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HBCFODLC_01266 8.38e-152 - - - GM - - - NAD(P)H-binding
HBCFODLC_01267 6.61e-179 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
HBCFODLC_01268 3.55e-79 - - - I - - - sulfurtransferase activity
HBCFODLC_01269 6.7e-102 yphH - - S - - - Cupin domain
HBCFODLC_01270 1.17e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HBCFODLC_01271 2.15e-151 - - - GM - - - NAD(P)H-binding
HBCFODLC_01272 4.39e-221 - - - C - - - C4-dicarboxylate transmembrane transporter activity
HBCFODLC_01273 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HBCFODLC_01274 5.26e-96 - - - - - - - -
HBCFODLC_01275 2.02e-215 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HBCFODLC_01276 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HBCFODLC_01277 5.23e-97 - - - S - - - Psort location Cytoplasmic, score
HBCFODLC_01278 6.14e-282 - - - T - - - diguanylate cyclase
HBCFODLC_01279 5.72e-157 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
HBCFODLC_01280 8.76e-121 - - - - - - - -
HBCFODLC_01281 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HBCFODLC_01282 1.58e-72 nudA - - S - - - ASCH
HBCFODLC_01283 2.42e-139 - - - S - - - SdpI/YhfL protein family
HBCFODLC_01284 3.03e-130 - - - M - - - Lysin motif
HBCFODLC_01285 4.61e-101 - - - M - - - LysM domain
HBCFODLC_01286 4.4e-101 - - - K - - - helix_turn_helix, mercury resistance
HBCFODLC_01287 7.8e-238 - - - GM - - - Male sterility protein
HBCFODLC_01288 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_01289 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_01290 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HBCFODLC_01291 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HBCFODLC_01292 1.24e-194 - - - K - - - Helix-turn-helix domain
HBCFODLC_01293 1.21e-73 - - - - - - - -
HBCFODLC_01294 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HBCFODLC_01295 1.01e-84 - - - - - - - -
HBCFODLC_01296 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
HBCFODLC_01297 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_01298 7.89e-124 - - - P - - - Cadmium resistance transporter
HBCFODLC_01299 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HBCFODLC_01300 1.81e-150 - - - S - - - SNARE associated Golgi protein
HBCFODLC_01301 7.03e-62 - - - - - - - -
HBCFODLC_01302 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
HBCFODLC_01303 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HBCFODLC_01304 4.08e-158 - - - K - - - Helix-turn-helix XRE-family like proteins
HBCFODLC_01305 2.88e-106 gtcA3 - - S - - - GtrA-like protein
HBCFODLC_01306 2.93e-169 zmp3 - - O - - - Zinc-dependent metalloprotease
HBCFODLC_01307 1.15e-43 - - - - - - - -
HBCFODLC_01309 1.8e-270 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
HBCFODLC_01310 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HBCFODLC_01311 5.64e-194 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HBCFODLC_01312 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
HBCFODLC_01313 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_01314 1.09e-42 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HBCFODLC_01315 2.15e-83 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HBCFODLC_01316 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
HBCFODLC_01317 2.35e-243 - - - S - - - Cell surface protein
HBCFODLC_01318 1.2e-83 - - - - - - - -
HBCFODLC_01319 0.0 - - - - - - - -
HBCFODLC_01320 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_01321 2.48e-199 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HBCFODLC_01322 6.24e-152 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HBCFODLC_01323 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HBCFODLC_01324 8.08e-154 ydgI3 - - C - - - Nitroreductase family
HBCFODLC_01325 1.9e-126 - - - K - - - Transcriptional regulator, MarR family
HBCFODLC_01326 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HBCFODLC_01327 5.52e-209 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HBCFODLC_01328 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
HBCFODLC_01329 6.43e-148 - - - K - - - Transcriptional regulator C-terminal region
HBCFODLC_01330 3.53e-227 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
HBCFODLC_01331 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
HBCFODLC_01332 3.43e-206 yicL - - EG - - - EamA-like transporter family
HBCFODLC_01333 9.5e-303 - - - M - - - Collagen binding domain
HBCFODLC_01334 0.0 - - - I - - - acetylesterase activity
HBCFODLC_01335 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HBCFODLC_01336 2.78e-176 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HBCFODLC_01337 4.29e-50 - - - - - - - -
HBCFODLC_01339 2.79e-184 - - - S - - - zinc-ribbon domain
HBCFODLC_01340 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HBCFODLC_01341 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HBCFODLC_01342 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
HBCFODLC_01343 5.12e-212 - - - K - - - LysR substrate binding domain
HBCFODLC_01344 1.84e-134 - - - - - - - -
HBCFODLC_01345 3.7e-30 - - - - - - - -
HBCFODLC_01346 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBCFODLC_01347 1.59e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HBCFODLC_01348 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HBCFODLC_01349 1.56e-108 - - - - - - - -
HBCFODLC_01350 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HBCFODLC_01351 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HBCFODLC_01352 2.82e-163 - - - T - - - Putative diguanylate phosphodiesterase
HBCFODLC_01353 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
HBCFODLC_01354 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HBCFODLC_01355 2e-52 - - - S - - - Cytochrome B5
HBCFODLC_01356 0.0 - - - - - - - -
HBCFODLC_01357 6.11e-169 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HBCFODLC_01358 4.93e-207 - - - I - - - alpha/beta hydrolase fold
HBCFODLC_01359 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HBCFODLC_01360 1.76e-298 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HBCFODLC_01361 0.0 - - - E ko:K03294 - ko00000 Amino acid permease
HBCFODLC_01362 5.22e-229 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HBCFODLC_01363 2.78e-222 ropB - - K - - - Helix-turn-helix XRE-family like proteins
HBCFODLC_01364 4.4e-270 - - - EGP - - - Major facilitator Superfamily
HBCFODLC_01365 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
HBCFODLC_01366 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HBCFODLC_01367 5.69e-191 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HBCFODLC_01368 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HBCFODLC_01369 6.26e-289 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_01370 3.05e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HBCFODLC_01371 9.05e-140 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HBCFODLC_01372 1.73e-201 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HBCFODLC_01373 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HBCFODLC_01374 1.59e-143 - - - K - - - Transcriptional regulator (TetR family)
HBCFODLC_01375 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
HBCFODLC_01378 7.5e-238 - - - EGP - - - Major Facilitator
HBCFODLC_01379 1.68e-67 - - - EGP - - - Major Facilitator
HBCFODLC_01380 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_01381 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_01383 1.8e-249 - - - C - - - Aldo/keto reductase family
HBCFODLC_01384 1.86e-132 - - - M - - - Protein of unknown function (DUF3737)
HBCFODLC_01385 2.17e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HBCFODLC_01386 5.52e-133 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HBCFODLC_01387 3.24e-114 - - - - - - - -
HBCFODLC_01388 6.11e-48 - - - - - - - -
HBCFODLC_01389 7.52e-80 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HBCFODLC_01390 7.54e-125 - - - - - - - -
HBCFODLC_01392 1.73e-67 - - - - - - - -
HBCFODLC_01393 4.78e-65 - - - - - - - -
HBCFODLC_01394 5.96e-152 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HBCFODLC_01395 5.01e-227 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HBCFODLC_01396 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HBCFODLC_01397 2.56e-76 - - - - - - - -
HBCFODLC_01398 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBCFODLC_01399 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HBCFODLC_01400 5.97e-151 yjcF - - J - - - HAD-hyrolase-like
HBCFODLC_01401 3.23e-214 - - - G - - - Fructosamine kinase
HBCFODLC_01402 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HBCFODLC_01403 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HBCFODLC_01404 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HBCFODLC_01405 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBCFODLC_01406 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBCFODLC_01407 1.92e-286 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HBCFODLC_01408 7.36e-220 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HBCFODLC_01409 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
HBCFODLC_01410 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HBCFODLC_01411 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HBCFODLC_01412 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HBCFODLC_01413 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HBCFODLC_01414 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HBCFODLC_01415 8.11e-95 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HBCFODLC_01416 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBCFODLC_01417 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HBCFODLC_01418 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HBCFODLC_01419 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HBCFODLC_01420 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HBCFODLC_01421 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HBCFODLC_01422 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HBCFODLC_01423 2.1e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_01424 1.56e-257 - - - - - - - -
HBCFODLC_01425 5.21e-254 - - - - - - - -
HBCFODLC_01426 2.11e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HBCFODLC_01427 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_01428 0.000138 yjdF - - S - - - Protein of unknown function (DUF2992)
HBCFODLC_01429 1.28e-148 - - - S - - - Psort location CytoplasmicMembrane, score
HBCFODLC_01430 5.9e-103 - - - K - - - MarR family
HBCFODLC_01431 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HBCFODLC_01433 4.17e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_01434 1.27e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HBCFODLC_01435 2.01e-266 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HBCFODLC_01436 2.72e-135 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HBCFODLC_01437 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HBCFODLC_01439 7.96e-223 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HBCFODLC_01440 1.41e-207 - - - K - - - Transcriptional regulator
HBCFODLC_01441 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
HBCFODLC_01442 1.51e-147 - - - GM - - - NmrA-like family
HBCFODLC_01443 1.36e-208 - - - S - - - Alpha beta hydrolase
HBCFODLC_01444 3.69e-169 - - - K - - - Helix-turn-helix domain, rpiR family
HBCFODLC_01445 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HBCFODLC_01446 1.1e-158 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HBCFODLC_01447 0.0 - - - S - - - Zinc finger, swim domain protein
HBCFODLC_01448 1.77e-149 - - - GM - - - epimerase
HBCFODLC_01449 3.27e-92 - - - S - - - Protein of unknown function (DUF1722)
HBCFODLC_01450 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
HBCFODLC_01451 1.25e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HBCFODLC_01452 4.14e-177 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HBCFODLC_01453 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HBCFODLC_01454 1.8e-271 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HBCFODLC_01455 4.38e-102 - - - K - - - Transcriptional regulator
HBCFODLC_01456 4.6e-307 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
HBCFODLC_01457 3.8e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HBCFODLC_01458 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HBCFODLC_01459 5.25e-233 - - - C - - - Zinc-binding dehydrogenase
HBCFODLC_01460 9.39e-285 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HBCFODLC_01461 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HBCFODLC_01462 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HBCFODLC_01463 1.98e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HBCFODLC_01464 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
HBCFODLC_01465 6.5e-215 mleR - - K - - - LysR family
HBCFODLC_01466 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HBCFODLC_01467 9.09e-213 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HBCFODLC_01468 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HBCFODLC_01469 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
HBCFODLC_01470 2.56e-34 - - - - - - - -
HBCFODLC_01471 0.0 - - - S ko:K06889 - ko00000 Alpha beta
HBCFODLC_01472 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HBCFODLC_01473 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HBCFODLC_01474 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HBCFODLC_01475 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HBCFODLC_01476 1.83e-158 - - - S - - - protein conserved in bacteria
HBCFODLC_01477 4.87e-234 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HBCFODLC_01478 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HBCFODLC_01479 9.47e-236 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HBCFODLC_01480 2.92e-147 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HBCFODLC_01481 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HBCFODLC_01482 1.13e-120 yebE - - S - - - UPF0316 protein
HBCFODLC_01483 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HBCFODLC_01484 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HBCFODLC_01485 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HBCFODLC_01486 9.48e-263 camS - - S - - - sex pheromone
HBCFODLC_01487 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBCFODLC_01488 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HBCFODLC_01489 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBCFODLC_01490 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HBCFODLC_01491 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBCFODLC_01492 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_01493 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HBCFODLC_01494 4.26e-308 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_01495 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HBCFODLC_01496 5.63e-196 gntR - - K - - - rpiR family
HBCFODLC_01497 2.82e-188 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HBCFODLC_01498 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
HBCFODLC_01499 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HBCFODLC_01500 4.76e-246 mocA - - S - - - Oxidoreductase
HBCFODLC_01501 9.36e-317 yfmL - - L - - - DEAD DEAH box helicase
HBCFODLC_01503 3.93e-99 - - - T - - - Universal stress protein family
HBCFODLC_01504 3.82e-316 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_01505 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HBCFODLC_01507 7.62e-97 - - - - - - - -
HBCFODLC_01508 2.9e-139 - - - - - - - -
HBCFODLC_01509 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HBCFODLC_01510 1.15e-281 pbpX - - V - - - Beta-lactamase
HBCFODLC_01511 4.75e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HBCFODLC_01512 6.87e-204 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HBCFODLC_01513 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HBCFODLC_01514 1.24e-283 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HBCFODLC_01515 1.29e-237 - - - M - - - Capsular polysaccharide synthesis protein
HBCFODLC_01516 3.17e-260 - - - M - - - Glycosyl transferases group 1
HBCFODLC_01517 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HBCFODLC_01520 1.48e-71 - - - - - - - -
HBCFODLC_01521 2.02e-39 - - - - - - - -
HBCFODLC_01522 1.69e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HBCFODLC_01523 3.47e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
HBCFODLC_01524 6.62e-66 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
HBCFODLC_01525 2.05e-55 - - - - - - - -
HBCFODLC_01526 1.49e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
HBCFODLC_01527 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
HBCFODLC_01528 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
HBCFODLC_01529 1.79e-211 - - - I - - - Diacylglycerol kinase catalytic domain
HBCFODLC_01530 1.51e-48 - - - - - - - -
HBCFODLC_01531 5.79e-21 - - - - - - - -
HBCFODLC_01532 2.22e-55 - - - S - - - transglycosylase associated protein
HBCFODLC_01533 4e-40 - - - S - - - CsbD-like
HBCFODLC_01534 1.06e-53 - - - - - - - -
HBCFODLC_01535 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HBCFODLC_01536 8.39e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HBCFODLC_01537 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HBCFODLC_01538 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HBCFODLC_01539 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
HBCFODLC_01540 3.72e-68 - - - - - - - -
HBCFODLC_01541 6.78e-60 - - - - - - - -
HBCFODLC_01542 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBCFODLC_01543 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HBCFODLC_01544 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HBCFODLC_01545 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HBCFODLC_01546 2.06e-158 - - - S - - - Domain of unknown function (DUF4767)
HBCFODLC_01547 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HBCFODLC_01548 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HBCFODLC_01549 1.55e-252 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HBCFODLC_01550 8.61e-251 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HBCFODLC_01551 6.45e-265 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HBCFODLC_01552 2.7e-231 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HBCFODLC_01553 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HBCFODLC_01554 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HBCFODLC_01555 1.07e-108 ypmB - - S - - - protein conserved in bacteria
HBCFODLC_01556 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HBCFODLC_01557 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HBCFODLC_01558 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
HBCFODLC_01560 2.53e-242 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBCFODLC_01561 8.54e-143 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_01562 5.51e-204 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HBCFODLC_01563 1.31e-109 - - - T - - - Universal stress protein family
HBCFODLC_01564 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HBCFODLC_01565 5.92e-236 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HBCFODLC_01566 8.37e-231 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HBCFODLC_01567 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HBCFODLC_01568 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HBCFODLC_01569 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
HBCFODLC_01570 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HBCFODLC_01572 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HBCFODLC_01573 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HBCFODLC_01574 3.27e-311 - - - P - - - Major Facilitator Superfamily
HBCFODLC_01575 4.17e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HBCFODLC_01576 1.93e-96 - - - S - - - SnoaL-like domain
HBCFODLC_01577 1.66e-256 - - - M - - - Glycosyltransferase, group 2 family protein
HBCFODLC_01578 5.99e-268 mccF - - V - - - LD-carboxypeptidase
HBCFODLC_01579 1.42e-21 - - - K - - - Acetyltransferase (GNAT) domain
HBCFODLC_01580 3.19e-45 - - - K - - - Acetyltransferase (GNAT) domain
HBCFODLC_01581 2.13e-312 - - - M ko:K07273 - ko00000 hydrolase, family 25
HBCFODLC_01582 7.44e-237 - - - V - - - LD-carboxypeptidase
HBCFODLC_01583 1.71e-160 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HBCFODLC_01584 3.99e-158 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HBCFODLC_01585 6.79e-249 - - - - - - - -
HBCFODLC_01586 1.29e-187 - - - S - - - hydrolase activity, acting on ester bonds
HBCFODLC_01587 1.47e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
HBCFODLC_01588 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HBCFODLC_01589 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
HBCFODLC_01590 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HBCFODLC_01591 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HBCFODLC_01592 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HBCFODLC_01593 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HBCFODLC_01594 1.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HBCFODLC_01595 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HBCFODLC_01596 4.94e-146 - - - G - - - Phosphoglycerate mutase family
HBCFODLC_01597 1.9e-93 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HBCFODLC_01599 1.92e-168 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HBCFODLC_01600 2.08e-92 - - - S - - - LuxR family transcriptional regulator
HBCFODLC_01601 1.19e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
HBCFODLC_01602 1.37e-119 - - - F - - - NUDIX domain
HBCFODLC_01603 2.63e-209 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_01604 1.6e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HBCFODLC_01605 0.0 FbpA - - K - - - Fibronectin-binding protein
HBCFODLC_01606 1.97e-87 - - - K - - - Transcriptional regulator
HBCFODLC_01607 1.11e-205 - - - S - - - EDD domain protein, DegV family
HBCFODLC_01608 3.65e-103 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HBCFODLC_01609 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
HBCFODLC_01610 3.03e-40 - - - - - - - -
HBCFODLC_01611 2.37e-65 - - - - - - - -
HBCFODLC_01612 4.17e-192 - - - C - - - Domain of unknown function (DUF4931)
HBCFODLC_01613 1.47e-268 pmrB - - EGP - - - Major Facilitator Superfamily
HBCFODLC_01615 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
HBCFODLC_01616 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
HBCFODLC_01617 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
HBCFODLC_01618 4.5e-314 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HBCFODLC_01619 2.79e-181 - - - - - - - -
HBCFODLC_01620 7.79e-78 - - - - - - - -
HBCFODLC_01621 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HBCFODLC_01622 2.02e-291 - - - - - - - -
HBCFODLC_01623 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HBCFODLC_01624 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
HBCFODLC_01625 5.37e-112 - - - S - - - NusG domain II
HBCFODLC_01626 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HBCFODLC_01627 3.19e-194 - - - S - - - FMN_bind
HBCFODLC_01628 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HBCFODLC_01629 3.42e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBCFODLC_01630 3.47e-212 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBCFODLC_01631 2.49e-186 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBCFODLC_01632 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HBCFODLC_01633 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HBCFODLC_01634 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HBCFODLC_01635 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
HBCFODLC_01636 5.93e-236 - - - S - - - Membrane
HBCFODLC_01637 1.35e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HBCFODLC_01638 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBCFODLC_01639 2.45e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBCFODLC_01640 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
HBCFODLC_01641 3.82e-255 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HBCFODLC_01642 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HBCFODLC_01643 1.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
HBCFODLC_01644 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
HBCFODLC_01645 9.01e-227 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
HBCFODLC_01646 1.89e-255 - - - K - - - Helix-turn-helix domain
HBCFODLC_01647 7.77e-197 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HBCFODLC_01648 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HBCFODLC_01649 4.32e-181 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HBCFODLC_01650 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HBCFODLC_01651 1.18e-66 - - - - - - - -
HBCFODLC_01652 9.2e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HBCFODLC_01653 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HBCFODLC_01654 8.69e-230 citR - - K - - - sugar-binding domain protein
HBCFODLC_01655 1.92e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HBCFODLC_01656 9.18e-243 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HBCFODLC_01657 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HBCFODLC_01658 3.32e-210 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HBCFODLC_01659 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HBCFODLC_01660 7.35e-99 yjcF - - S - - - Acetyltransferase (GNAT) domain
HBCFODLC_01661 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HBCFODLC_01662 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HBCFODLC_01663 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HBCFODLC_01664 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HBCFODLC_01665 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
HBCFODLC_01666 2.57e-128 - - - C - - - Nitroreductase family
HBCFODLC_01667 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HBCFODLC_01668 1.03e-210 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBCFODLC_01669 8.1e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HBCFODLC_01670 3.16e-232 - - - GK - - - ROK family
HBCFODLC_01671 2.08e-199 - 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HBCFODLC_01672 2.48e-174 rdrA - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HBCFODLC_01673 0.0 pflD 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HBCFODLC_01674 4.3e-228 - - - K - - - sugar-binding domain protein
HBCFODLC_01675 1.81e-160 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
HBCFODLC_01676 2.13e-182 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HBCFODLC_01677 2.89e-224 ccpB - - K - - - lacI family
HBCFODLC_01678 6.43e-204 - - - K - - - Helix-turn-helix domain, rpiR family
HBCFODLC_01679 2.13e-228 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HBCFODLC_01680 1.89e-254 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HBCFODLC_01681 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
HBCFODLC_01682 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HBCFODLC_01683 1.28e-152 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HBCFODLC_01684 6.51e-247 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HBCFODLC_01685 8.63e-275 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HBCFODLC_01686 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HBCFODLC_01687 1.2e-123 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HBCFODLC_01688 1.48e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HBCFODLC_01689 0.0 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HBCFODLC_01690 1.12e-87 - - - - - - - -
HBCFODLC_01691 4.49e-315 - - - M - - - Glycosyl transferase family group 2
HBCFODLC_01692 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HBCFODLC_01693 3.59e-204 - - - L - - - Phage integrase, N-terminal SAM-like domain
HBCFODLC_01694 1.07e-43 - - - S - - - YozE SAM-like fold
HBCFODLC_01695 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBCFODLC_01696 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HBCFODLC_01697 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HBCFODLC_01698 3.82e-228 - - - K - - - Transcriptional regulator
HBCFODLC_01699 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBCFODLC_01700 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBCFODLC_01701 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HBCFODLC_01702 8.93e-218 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HBCFODLC_01703 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HBCFODLC_01704 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HBCFODLC_01705 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HBCFODLC_01706 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HBCFODLC_01707 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBCFODLC_01708 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HBCFODLC_01709 8.64e-177 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBCFODLC_01710 2.25e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HBCFODLC_01712 5.13e-292 XK27_05470 - - E - - - Methionine synthase
HBCFODLC_01713 7.35e-221 cpsY - - K - - - Transcriptional regulator, LysR family
HBCFODLC_01714 1.55e-223 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HBCFODLC_01715 2.59e-162 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HBCFODLC_01716 1.28e-254 XK27_00915 - - C - - - Luciferase-like monooxygenase
HBCFODLC_01717 0.0 qacA - - EGP - - - Major Facilitator
HBCFODLC_01718 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HBCFODLC_01719 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
HBCFODLC_01720 8.07e-148 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HBCFODLC_01721 3.34e-209 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
HBCFODLC_01722 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
HBCFODLC_01723 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBCFODLC_01724 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HBCFODLC_01725 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_01726 6.46e-109 - - - - - - - -
HBCFODLC_01727 8.95e-292 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HBCFODLC_01728 2.92e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HBCFODLC_01729 9.1e-193 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HBCFODLC_01730 7.1e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HBCFODLC_01731 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HBCFODLC_01732 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HBCFODLC_01733 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HBCFODLC_01734 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HBCFODLC_01735 1.25e-39 - - - M - - - Lysin motif
HBCFODLC_01736 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HBCFODLC_01737 3.38e-252 - - - S - - - Helix-turn-helix domain
HBCFODLC_01738 7.83e-127 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HBCFODLC_01739 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HBCFODLC_01740 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBCFODLC_01741 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBCFODLC_01742 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBCFODLC_01743 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HBCFODLC_01744 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
HBCFODLC_01745 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
HBCFODLC_01746 0.0 mdr - - EGP - - - Major Facilitator
HBCFODLC_01747 3.39e-274 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HBCFODLC_01748 5.79e-158 - - - - - - - -
HBCFODLC_01749 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HBCFODLC_01750 4.08e-218 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HBCFODLC_01751 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HBCFODLC_01752 1.52e-241 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HBCFODLC_01753 8.01e-294 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HBCFODLC_01755 1.25e-201 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HBCFODLC_01756 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
HBCFODLC_01757 1.25e-124 - - - - - - - -
HBCFODLC_01758 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
HBCFODLC_01759 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
HBCFODLC_01760 3.49e-246 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
HBCFODLC_01761 1.22e-166 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
HBCFODLC_01762 5.06e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
HBCFODLC_01763 1.54e-272 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
HBCFODLC_01764 1.94e-271 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HBCFODLC_01765 6.14e-53 - - - - - - - -
HBCFODLC_01766 4.08e-291 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_01767 1.92e-161 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HBCFODLC_01768 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HBCFODLC_01769 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HBCFODLC_01770 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HBCFODLC_01771 2.98e-90 - - - - - - - -
HBCFODLC_01772 1.22e-125 - - - - - - - -
HBCFODLC_01773 1.76e-68 - - - - - - - -
HBCFODLC_01774 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HBCFODLC_01775 3.61e-113 - - - - - - - -
HBCFODLC_01776 2.61e-282 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
HBCFODLC_01777 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_01778 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
HBCFODLC_01779 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HBCFODLC_01780 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HBCFODLC_01782 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HBCFODLC_01783 1.2e-91 - - - - - - - -
HBCFODLC_01784 7.73e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HBCFODLC_01785 2.25e-203 dkgB - - S - - - reductase
HBCFODLC_01786 6.07e-117 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HBCFODLC_01787 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
HBCFODLC_01788 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HBCFODLC_01789 3.68e-151 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HBCFODLC_01790 1.18e-222 - - - L - - - Domain of unknown function (DUF4373)
HBCFODLC_01791 4.49e-185 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HBCFODLC_01792 1.52e-206 - - - L ko:K07455 - ko00000,ko03400 RecT family
HBCFODLC_01793 6.6e-96 - - - - - - - -
HBCFODLC_01796 3.66e-127 - - - - - - - -
HBCFODLC_01799 1.13e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
HBCFODLC_01800 8.29e-51 - - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
HBCFODLC_01802 2.06e-50 - - - K - - - Helix-turn-helix
HBCFODLC_01803 1.32e-80 - - - K - - - Helix-turn-helix domain
HBCFODLC_01804 6.41e-101 - - - E - - - IrrE N-terminal-like domain
HBCFODLC_01805 9.61e-75 - - - - - - - -
HBCFODLC_01806 2.42e-209 - - - M - - - Host cell surface-exposed lipoprotein
HBCFODLC_01810 1.12e-252 - - - S ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HBCFODLC_01812 4.82e-297 - - - L - - - Belongs to the 'phage' integrase family
HBCFODLC_01814 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HBCFODLC_01815 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HBCFODLC_01816 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HBCFODLC_01817 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HBCFODLC_01818 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HBCFODLC_01819 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HBCFODLC_01820 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HBCFODLC_01821 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HBCFODLC_01822 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
HBCFODLC_01823 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
HBCFODLC_01824 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBCFODLC_01825 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HBCFODLC_01826 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HBCFODLC_01827 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBCFODLC_01828 4.91e-265 yacL - - S - - - domain protein
HBCFODLC_01829 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HBCFODLC_01830 3.29e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HBCFODLC_01831 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HBCFODLC_01832 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HBCFODLC_01833 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HBCFODLC_01834 1.94e-148 zmp2 - - O - - - Zinc-dependent metalloprotease
HBCFODLC_01835 3.3e-166 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBCFODLC_01836 6.04e-227 - - - EG - - - EamA-like transporter family
HBCFODLC_01837 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HBCFODLC_01838 3.97e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HBCFODLC_01839 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HBCFODLC_01840 1.1e-185 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HBCFODLC_01841 9.45e-317 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
HBCFODLC_01842 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
HBCFODLC_01843 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBCFODLC_01844 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HBCFODLC_01845 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HBCFODLC_01846 0.0 levR - - K - - - Sigma-54 interaction domain
HBCFODLC_01847 6.52e-272 - - - EGP - - - Major facilitator Superfamily
HBCFODLC_01848 3.7e-88 manO - - S - - - Domain of unknown function (DUF956)
HBCFODLC_01849 9.12e-154 acpT 2.7.8.7 - H ko:K00997,ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 lysine biosynthetic process via aminoadipic acid
HBCFODLC_01850 0.0 - - - Q - - - Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBCFODLC_01851 1.21e-241 - - - H - - - HD domain
HBCFODLC_01852 6.58e-88 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HBCFODLC_01853 0.0 - - - Q - - - AMP-binding enzyme
HBCFODLC_01854 6.03e-218 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HBCFODLC_01855 1.93e-175 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HBCFODLC_01856 3.35e-220 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HBCFODLC_01857 1e-200 - - - G - - - Peptidase_C39 like family
HBCFODLC_01859 8.77e-204 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HBCFODLC_01860 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HBCFODLC_01861 7.89e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HBCFODLC_01862 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HBCFODLC_01863 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
HBCFODLC_01864 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HBCFODLC_01865 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HBCFODLC_01866 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HBCFODLC_01867 6.9e-178 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HBCFODLC_01868 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HBCFODLC_01869 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HBCFODLC_01870 9.25e-176 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBCFODLC_01871 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HBCFODLC_01872 1.59e-247 ysdE - - P - - - Citrate transporter
HBCFODLC_01873 4.58e-214 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HBCFODLC_01874 9.69e-72 - - - S - - - Cupin domain
HBCFODLC_01875 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
HBCFODLC_01879 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
HBCFODLC_01880 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HBCFODLC_01883 1.6e-221 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBCFODLC_01884 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HBCFODLC_01885 1.02e-155 - - - S - - - repeat protein
HBCFODLC_01886 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
HBCFODLC_01887 0.0 - - - N - - - domain, Protein
HBCFODLC_01888 1.22e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
HBCFODLC_01889 3.57e-154 - - - N - - - WxL domain surface cell wall-binding
HBCFODLC_01890 8.03e-151 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HBCFODLC_01891 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HBCFODLC_01892 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HBCFODLC_01893 3.48e-75 XK27_04120 - - S - - - Putative amino acid metabolism
HBCFODLC_01894 7.76e-280 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HBCFODLC_01895 3.53e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBCFODLC_01896 7.74e-47 - - - - - - - -
HBCFODLC_01897 8.62e-126 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HBCFODLC_01898 4.22e-243 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HBCFODLC_01899 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBCFODLC_01900 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HBCFODLC_01901 2.06e-187 ylmH - - S - - - S4 domain protein
HBCFODLC_01902 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HBCFODLC_01903 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HBCFODLC_01904 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBCFODLC_01905 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HBCFODLC_01906 4.05e-209 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HBCFODLC_01907 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HBCFODLC_01908 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HBCFODLC_01909 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBCFODLC_01910 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HBCFODLC_01911 7.01e-76 ftsL - - D - - - Cell division protein FtsL
HBCFODLC_01912 2.58e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HBCFODLC_01913 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HBCFODLC_01914 3.35e-84 - - - S - - - Protein of unknown function (DUF3397)
HBCFODLC_01915 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HBCFODLC_01916 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HBCFODLC_01917 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HBCFODLC_01918 4.32e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HBCFODLC_01919 2.17e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HBCFODLC_01921 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HBCFODLC_01922 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HBCFODLC_01923 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
HBCFODLC_01924 1.33e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HBCFODLC_01925 5.57e-247 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HBCFODLC_01926 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HBCFODLC_01927 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HBCFODLC_01928 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBCFODLC_01929 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HBCFODLC_01930 3.86e-149 yjbH - - Q - - - Thioredoxin
HBCFODLC_01931 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HBCFODLC_01932 4.93e-268 coiA - - S ko:K06198 - ko00000 Competence protein
HBCFODLC_01933 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HBCFODLC_01934 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HBCFODLC_01935 5.33e-216 - - - L - - - DnaD domain protein
HBCFODLC_01936 6.9e-157 - - - S - - - Protein of unknown function (DUF669)
HBCFODLC_01937 1.51e-155 - - - S - - - AAA domain
HBCFODLC_01938 1.71e-111 - - - - - - - -
HBCFODLC_01941 1.01e-31 - - - S ko:K09946 - ko00000 Domain of unknown function (DUF1508)
HBCFODLC_01942 3.72e-111 - - - - - - - -
HBCFODLC_01943 6.59e-72 - - - - - - - -
HBCFODLC_01945 4.98e-07 - - - K - - - Transcriptional
HBCFODLC_01946 1.38e-82 - - - K - - - Helix-turn-helix XRE-family like proteins
HBCFODLC_01947 8.13e-99 - - - E - - - IrrE N-terminal-like domain
HBCFODLC_01948 4.1e-73 - - - - - - - -
HBCFODLC_01949 2.2e-251 - - - S ko:K07504 - ko00000 Type I restriction enzyme R protein N terminus (HSDR_N)
HBCFODLC_01956 0.0 - - - S - - - AAA ATPase domain
HBCFODLC_01957 8.98e-224 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 DNA methyltransferase
HBCFODLC_01958 9.78e-281 int3 - - L - - - Belongs to the 'phage' integrase family
HBCFODLC_01960 1.98e-40 - - - - - - - -
HBCFODLC_01963 3.71e-83 - - - - - - - -
HBCFODLC_01964 1.44e-56 - - - S - - - Phage gp6-like head-tail connector protein
HBCFODLC_01965 0.0 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HBCFODLC_01966 6.7e-264 - - - S - - - Phage portal protein
HBCFODLC_01967 0.000349 - - - - - - - -
HBCFODLC_01968 0.0 terL - - S - - - overlaps another CDS with the same product name
HBCFODLC_01969 9.4e-110 terS - - L - - - Phage terminase, small subunit
HBCFODLC_01970 3.97e-93 - - - L - - - HNH endonuclease
HBCFODLC_01971 1.13e-71 - - - S - - - Head-tail joining protein
HBCFODLC_01972 3.2e-37 - - - - - - - -
HBCFODLC_01973 3.41e-112 - - - - - - - -
HBCFODLC_01974 0.0 - - - S - - - Virulence-associated protein E
HBCFODLC_01975 1.85e-197 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
HBCFODLC_01978 6.01e-17 - - - - - - - -
HBCFODLC_01981 2.64e-122 - - - K - - - sequence-specific DNA binding
HBCFODLC_01982 4.47e-126 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
HBCFODLC_01983 1e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HBCFODLC_01984 1.3e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HBCFODLC_01985 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HBCFODLC_01986 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HBCFODLC_01987 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
HBCFODLC_01988 1.1e-56 - - - - - - - -
HBCFODLC_01989 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HBCFODLC_01990 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HBCFODLC_01991 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_01992 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HBCFODLC_01993 2.6e-185 - - - - - - - -
HBCFODLC_01994 1.21e-94 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
HBCFODLC_01995 1.4e-306 tagB 2.7.8.12, 2.7.8.45 - M ko:K09809,ko:K21591 - ko00000,ko01000 glycerophosphotransferase
HBCFODLC_01996 0.0 tagF2 2.7.8.12 - H ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HBCFODLC_01997 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HBCFODLC_01998 2.34e-93 - - - - - - - -
HBCFODLC_01999 8.9e-96 ywnA - - K - - - Transcriptional regulator
HBCFODLC_02000 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02001 4.02e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HBCFODLC_02002 1.15e-152 - - - - - - - -
HBCFODLC_02003 2.5e-58 - - - - - - - -
HBCFODLC_02004 1.55e-55 - - - - - - - -
HBCFODLC_02005 0.0 ydiC - - EGP - - - Major Facilitator
HBCFODLC_02006 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
HBCFODLC_02007 0.0 hpk2 - - T - - - Histidine kinase
HBCFODLC_02008 2.31e-166 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
HBCFODLC_02009 2.42e-65 - - - - - - - -
HBCFODLC_02010 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
HBCFODLC_02011 2.39e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_02012 3.35e-75 - - - - - - - -
HBCFODLC_02013 2.87e-56 - - - - - - - -
HBCFODLC_02014 1.76e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HBCFODLC_02015 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HBCFODLC_02016 5.2e-64 - - - - - - - -
HBCFODLC_02017 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HBCFODLC_02018 1.17e-135 - - - K - - - transcriptional regulator
HBCFODLC_02019 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HBCFODLC_02020 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HBCFODLC_02021 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HBCFODLC_02022 1.84e-295 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HBCFODLC_02023 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_02024 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_02025 1.17e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_02026 9.85e-81 - - - M - - - Lysin motif
HBCFODLC_02027 1.31e-97 - - - M - - - LysM domain protein
HBCFODLC_02028 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
HBCFODLC_02029 4.47e-229 - - - - - - - -
HBCFODLC_02030 6.88e-170 - - - - - - - -
HBCFODLC_02031 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
HBCFODLC_02032 3.01e-75 - - - - - - - -
HBCFODLC_02033 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBCFODLC_02034 2.65e-102 - - - S ko:K02348 - ko00000 GNAT family
HBCFODLC_02035 1.24e-99 - - - K - - - Transcriptional regulator
HBCFODLC_02036 1.17e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HBCFODLC_02037 2.18e-53 - - - - - - - -
HBCFODLC_02038 5.3e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_02039 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_02040 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_02041 8.8e-264 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HBCFODLC_02042 3.68e-125 - - - K - - - Cupin domain
HBCFODLC_02043 8.08e-110 - - - S - - - ASCH
HBCFODLC_02044 3.25e-112 - - - K - - - GNAT family
HBCFODLC_02045 2.14e-117 - - - K - - - acetyltransferase
HBCFODLC_02046 2.06e-30 - - - - - - - -
HBCFODLC_02047 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HBCFODLC_02048 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_02049 1.08e-243 - - - - - - - -
HBCFODLC_02050 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
HBCFODLC_02051 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HBCFODLC_02053 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
HBCFODLC_02054 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HBCFODLC_02055 7.28e-42 - - - - - - - -
HBCFODLC_02056 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HBCFODLC_02057 6.4e-54 - - - - - - - -
HBCFODLC_02058 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HBCFODLC_02059 3.67e-228 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HBCFODLC_02060 4.89e-82 - - - S - - - CHY zinc finger
HBCFODLC_02061 1.39e-287 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HBCFODLC_02062 1.1e-280 - - - - - - - -
HBCFODLC_02063 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HBCFODLC_02064 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HBCFODLC_02065 2.76e-59 - - - - - - - -
HBCFODLC_02066 2.39e-121 - - - K - - - Transcriptional regulator PadR-like family
HBCFODLC_02067 0.0 - - - P - - - Major Facilitator Superfamily
HBCFODLC_02068 1.05e-308 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HBCFODLC_02069 6.6e-229 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HBCFODLC_02070 8.95e-60 - - - - - - - -
HBCFODLC_02071 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
HBCFODLC_02072 7.16e-155 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HBCFODLC_02073 0.0 sufI - - Q - - - Multicopper oxidase
HBCFODLC_02074 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HBCFODLC_02075 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HBCFODLC_02076 1.96e-295 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HBCFODLC_02077 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HBCFODLC_02078 1.52e-103 - - - - - - - -
HBCFODLC_02079 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HBCFODLC_02080 3.66e-224 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HBCFODLC_02081 1.3e-209 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HBCFODLC_02082 0.0 - - - - - - - -
HBCFODLC_02083 1.42e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
HBCFODLC_02084 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HBCFODLC_02085 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_02086 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HBCFODLC_02087 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBCFODLC_02088 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
HBCFODLC_02089 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HBCFODLC_02090 0.0 - - - M - - - domain protein
HBCFODLC_02091 9.53e-285 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HBCFODLC_02092 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HBCFODLC_02093 5.01e-256 glmS2 - - M - - - SIS domain
HBCFODLC_02094 2.63e-36 - - - S - - - Belongs to the LOG family
HBCFODLC_02095 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HBCFODLC_02096 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HBCFODLC_02097 4.58e-216 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HBCFODLC_02098 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
HBCFODLC_02099 4.06e-211 - - - GM - - - NmrA-like family
HBCFODLC_02100 4.67e-90 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
HBCFODLC_02101 2.45e-94 spxA - - P ko:K16509 - ko00000 ArsC family
HBCFODLC_02102 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
HBCFODLC_02103 1.7e-70 - - - - - - - -
HBCFODLC_02104 1.22e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
HBCFODLC_02105 2.11e-82 - - - - - - - -
HBCFODLC_02106 1.36e-112 - - - - - - - -
HBCFODLC_02107 3.22e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HBCFODLC_02108 2.27e-74 - - - - - - - -
HBCFODLC_02109 4.79e-21 - - - - - - - -
HBCFODLC_02110 3.57e-150 - - - GM - - - NmrA-like family
HBCFODLC_02111 3.06e-108 - - - S ko:K02348 - ko00000 GNAT family
HBCFODLC_02112 1.63e-203 - - - EG - - - EamA-like transporter family
HBCFODLC_02113 2.66e-155 - - - S - - - membrane
HBCFODLC_02114 2.55e-145 - - - S - - - VIT family
HBCFODLC_02115 9.51e-61 - - - - - - - -
HBCFODLC_02116 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
HBCFODLC_02117 4.48e-162 - - - S - - - WxL domain surface cell wall-binding
HBCFODLC_02118 1.83e-235 - - - S - - - Cell surface protein
HBCFODLC_02119 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HBCFODLC_02120 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HBCFODLC_02121 6.36e-108 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBCFODLC_02122 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HBCFODLC_02123 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HBCFODLC_02124 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
HBCFODLC_02125 4.27e-126 dpsB - - P - - - Belongs to the Dps family
HBCFODLC_02126 1.01e-26 - - - - - - - -
HBCFODLC_02127 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
HBCFODLC_02128 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
HBCFODLC_02129 8.08e-184 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HBCFODLC_02130 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HBCFODLC_02131 1.77e-235 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HBCFODLC_02132 7.76e-168 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
HBCFODLC_02133 5.92e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HBCFODLC_02134 2.5e-232 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HBCFODLC_02135 2.36e-136 - - - K - - - transcriptional regulator
HBCFODLC_02136 3.46e-207 - - - S ko:K07045 - ko00000 Amidohydrolase
HBCFODLC_02137 2.56e-70 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
HBCFODLC_02138 1.53e-139 - - - - - - - -
HBCFODLC_02139 2.31e-277 - - - - - - - -
HBCFODLC_02140 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_02141 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_02142 1.3e-226 - - - O - - - protein import
HBCFODLC_02143 1.67e-292 amd - - E - - - Peptidase family M20/M25/M40
HBCFODLC_02144 2.96e-209 yhxD - - IQ - - - KR domain
HBCFODLC_02146 3.4e-93 - - - - - - - -
HBCFODLC_02147 5.2e-187 - - - K - - - Helix-turn-helix XRE-family like proteins
HBCFODLC_02148 0.0 - - - E - - - Amino Acid
HBCFODLC_02149 2.03e-87 lysM - - M - - - LysM domain
HBCFODLC_02150 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HBCFODLC_02151 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HBCFODLC_02152 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HBCFODLC_02153 3.65e-59 - - - S - - - Cupredoxin-like domain
HBCFODLC_02154 1.36e-84 - - - S - - - Cupredoxin-like domain
HBCFODLC_02155 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HBCFODLC_02156 2.81e-181 - - - K - - - Helix-turn-helix domain
HBCFODLC_02157 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
HBCFODLC_02158 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HBCFODLC_02159 0.0 - - - - - - - -
HBCFODLC_02160 2.69e-99 - - - - - - - -
HBCFODLC_02161 5.14e-246 - - - S - - - Cell surface protein
HBCFODLC_02162 6.65e-131 - - - S - - - WxL domain surface cell wall-binding
HBCFODLC_02163 7.15e-230 - - - C - - - Alcohol dehydrogenase GroES-like domain
HBCFODLC_02164 9.31e-93 - - - S - - - Iron-sulphur cluster biosynthesis
HBCFODLC_02165 3.33e-149 - - - S - - - GyrI-like small molecule binding domain
HBCFODLC_02166 1.59e-243 ynjC - - S - - - Cell surface protein
HBCFODLC_02167 2.7e-131 - - - S - - - WxL domain surface cell wall-binding
HBCFODLC_02168 1.47e-83 - - - - - - - -
HBCFODLC_02169 1.28e-312 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HBCFODLC_02170 4.13e-157 - - - - - - - -
HBCFODLC_02171 1.57e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
HBCFODLC_02172 2.21e-76 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HBCFODLC_02173 1.33e-156 ORF00048 - - - - - - -
HBCFODLC_02174 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
HBCFODLC_02175 1.81e-272 - - - EGP - - - Major Facilitator
HBCFODLC_02176 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
HBCFODLC_02177 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HBCFODLC_02178 1.38e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HBCFODLC_02179 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HBCFODLC_02180 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02181 2.65e-216 - - - GM - - - NmrA-like family
HBCFODLC_02182 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HBCFODLC_02183 0.0 - - - M - - - Glycosyl hydrolases family 25
HBCFODLC_02184 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
HBCFODLC_02185 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
HBCFODLC_02186 3.27e-170 - - - S - - - KR domain
HBCFODLC_02187 2.46e-127 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02188 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
HBCFODLC_02189 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
HBCFODLC_02190 1.97e-229 ydhF - - S - - - Aldo keto reductase
HBCFODLC_02191 0.0 yfjF - - U - - - Sugar (and other) transporter
HBCFODLC_02192 2.64e-141 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02193 1.22e-219 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HBCFODLC_02194 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HBCFODLC_02195 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBCFODLC_02196 8.17e-220 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBCFODLC_02197 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02198 6.73e-211 - - - GM - - - NmrA-like family
HBCFODLC_02199 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HBCFODLC_02200 1.4e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HBCFODLC_02201 6.38e-195 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HBCFODLC_02202 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
HBCFODLC_02203 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HBCFODLC_02204 2.22e-235 - - - S - - - Bacterial protein of unknown function (DUF916)
HBCFODLC_02205 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
HBCFODLC_02206 5.32e-270 - - - NU - - - Mycoplasma protein of unknown function, DUF285
HBCFODLC_02207 2.4e-152 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02208 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HBCFODLC_02211 2.97e-41 - - - - - - - -
HBCFODLC_02212 1.87e-74 - - - - - - - -
HBCFODLC_02213 3.55e-127 - - - S - - - Protein conserved in bacteria
HBCFODLC_02214 1.34e-232 - - - - - - - -
HBCFODLC_02215 4.11e-206 - - - - - - - -
HBCFODLC_02216 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HBCFODLC_02217 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HBCFODLC_02218 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HBCFODLC_02219 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HBCFODLC_02220 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HBCFODLC_02221 1.15e-89 yqhL - - P - - - Rhodanese-like protein
HBCFODLC_02222 3.99e-142 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HBCFODLC_02223 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HBCFODLC_02224 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HBCFODLC_02225 2.47e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HBCFODLC_02226 3.24e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBCFODLC_02227 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HBCFODLC_02228 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HBCFODLC_02229 0.0 - - - S - - - membrane
HBCFODLC_02230 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
HBCFODLC_02231 5.72e-99 - - - K - - - LytTr DNA-binding domain
HBCFODLC_02232 9.72e-146 - - - S - - - membrane
HBCFODLC_02233 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HBCFODLC_02234 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HBCFODLC_02235 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBCFODLC_02236 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBCFODLC_02237 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HBCFODLC_02238 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
HBCFODLC_02239 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HBCFODLC_02240 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBCFODLC_02241 2.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HBCFODLC_02242 8.45e-210 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBCFODLC_02243 1.21e-129 - - - S - - - SdpI/YhfL protein family
HBCFODLC_02244 4.07e-290 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HBCFODLC_02245 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HBCFODLC_02246 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HBCFODLC_02247 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HBCFODLC_02248 1.38e-155 csrR - - K - - - response regulator
HBCFODLC_02249 7.66e-312 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HBCFODLC_02250 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HBCFODLC_02251 6.84e-227 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBCFODLC_02252 1.3e-125 - - - S - - - Peptidase propeptide and YPEB domain
HBCFODLC_02254 9.96e-82 - - - - - - - -
HBCFODLC_02255 2.15e-71 - - - - - - - -
HBCFODLC_02256 5.07e-108 - - - M - - - PFAM NLP P60 protein
HBCFODLC_02257 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HBCFODLC_02258 4.45e-38 - - - - - - - -
HBCFODLC_02259 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HBCFODLC_02260 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02261 1.31e-114 - - - K - - - Winged helix DNA-binding domain
HBCFODLC_02262 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HBCFODLC_02263 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
HBCFODLC_02264 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
HBCFODLC_02265 0.0 - - - - - - - -
HBCFODLC_02266 2.41e-212 - - - S - - - Protein of unknown function (DUF1002)
HBCFODLC_02267 1.58e-66 - - - - - - - -
HBCFODLC_02268 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
HBCFODLC_02269 5.94e-118 ymdB - - S - - - Macro domain protein
HBCFODLC_02270 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HBCFODLC_02271 9.86e-32 - - - S - - - Protein of unknown function (DUF1093)
HBCFODLC_02272 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
HBCFODLC_02273 2.57e-171 - - - S - - - Putative threonine/serine exporter
HBCFODLC_02274 3.34e-210 yvgN - - C - - - Aldo keto reductase
HBCFODLC_02275 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HBCFODLC_02276 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HBCFODLC_02277 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HBCFODLC_02278 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HBCFODLC_02279 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
HBCFODLC_02280 7.28e-232 ybcH - - D ko:K06889 - ko00000 Alpha beta
HBCFODLC_02281 1.3e-284 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HBCFODLC_02282 1.2e-287 - - - L - - - Belongs to the 'phage' integrase family
HBCFODLC_02284 4.78e-152 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
HBCFODLC_02285 2.46e-57 - - - - - - - -
HBCFODLC_02286 1.15e-05 - - - - - - - -
HBCFODLC_02288 3.29e-71 - - - - - - - -
HBCFODLC_02289 1.02e-42 - - - - - - - -
HBCFODLC_02290 2.63e-179 - - - L - - - Primase C terminal 1 (PriCT-1)
HBCFODLC_02291 0.0 - - - S ko:K06919 - ko00000 DNA primase
HBCFODLC_02292 6.96e-44 - - - - - - - -
HBCFODLC_02294 7.85e-84 - - - - - - - -
HBCFODLC_02295 6.43e-96 - - - - - - - -
HBCFODLC_02297 3.99e-74 - - - - - - - -
HBCFODLC_02298 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HBCFODLC_02299 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
HBCFODLC_02300 4.39e-66 - - - - - - - -
HBCFODLC_02301 7.21e-35 - - - - - - - -
HBCFODLC_02302 1.76e-61 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HBCFODLC_02303 2.01e-247 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HBCFODLC_02304 2.07e-97 - - - S - - - COG NOG18757 non supervised orthologous group
HBCFODLC_02305 4.26e-54 - - - - - - - -
HBCFODLC_02306 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HBCFODLC_02307 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HBCFODLC_02308 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HBCFODLC_02309 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HBCFODLC_02310 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HBCFODLC_02311 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HBCFODLC_02312 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
HBCFODLC_02313 4.53e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
HBCFODLC_02314 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HBCFODLC_02315 1.58e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HBCFODLC_02316 7.29e-61 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
HBCFODLC_02317 2.47e-307 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HBCFODLC_02318 7.45e-150 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBCFODLC_02319 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBCFODLC_02320 5.43e-188 yxeH - - S - - - hydrolase
HBCFODLC_02321 4.89e-238 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HBCFODLC_02323 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HBCFODLC_02324 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HBCFODLC_02325 2.66e-222 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HBCFODLC_02326 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HBCFODLC_02327 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HBCFODLC_02328 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_02329 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_02330 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_02331 5.63e-253 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
HBCFODLC_02332 8.71e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HBCFODLC_02333 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_02334 4.82e-192 yleF - - K - - - Helix-turn-helix domain, rpiR family
HBCFODLC_02335 5.18e-104 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HBCFODLC_02336 2.02e-97 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HBCFODLC_02337 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HBCFODLC_02338 4.72e-286 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
HBCFODLC_02339 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HBCFODLC_02340 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HBCFODLC_02341 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_02342 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_02343 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
HBCFODLC_02344 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HBCFODLC_02345 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBCFODLC_02346 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBCFODLC_02347 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBCFODLC_02348 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HBCFODLC_02349 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HBCFODLC_02350 1.85e-104 yabR - - J ko:K07571 - ko00000 RNA binding
HBCFODLC_02351 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HBCFODLC_02353 7.72e-57 yabO - - J - - - S4 domain protein
HBCFODLC_02354 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HBCFODLC_02355 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBCFODLC_02356 8.63e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HBCFODLC_02357 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HBCFODLC_02358 0.0 - - - S - - - Putative peptidoglycan binding domain
HBCFODLC_02359 4.87e-148 - - - S - - - (CBS) domain
HBCFODLC_02360 1.3e-110 queT - - S - - - QueT transporter
HBCFODLC_02361 1.17e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HBCFODLC_02362 8.41e-281 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
HBCFODLC_02363 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HBCFODLC_02364 3.39e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HBCFODLC_02365 2.18e-245 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HBCFODLC_02366 9.1e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HBCFODLC_02367 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HBCFODLC_02368 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HBCFODLC_02369 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HBCFODLC_02370 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBCFODLC_02371 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HBCFODLC_02372 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HBCFODLC_02373 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HBCFODLC_02374 1.84e-189 - - - - - - - -
HBCFODLC_02375 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HBCFODLC_02376 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
HBCFODLC_02377 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HBCFODLC_02378 2.57e-274 - - - J - - - translation release factor activity
HBCFODLC_02379 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HBCFODLC_02380 1.29e-301 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HBCFODLC_02381 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBCFODLC_02382 2.41e-37 - - - - - - - -
HBCFODLC_02383 5.65e-171 - - - S - - - YheO-like PAS domain
HBCFODLC_02384 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HBCFODLC_02385 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HBCFODLC_02386 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
HBCFODLC_02387 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HBCFODLC_02388 2.87e-217 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBCFODLC_02389 1.01e-253 - - - S - - - Domain of unknown function (DUF4432)
HBCFODLC_02390 8.41e-314 - - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
HBCFODLC_02391 2.4e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HBCFODLC_02392 4.24e-219 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HBCFODLC_02393 5.68e-298 - - - F - - - ATP-grasp domain
HBCFODLC_02394 5.06e-280 - - - EGP - - - Transmembrane secretion effector
HBCFODLC_02395 2.02e-220 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase
HBCFODLC_02396 1.91e-51 ywqN - - S - - - (NAD(P)H-dependent
HBCFODLC_02397 4.33e-196 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, thiamine diphosphate binding domain
HBCFODLC_02398 0.0 lysZ 2.7.2.8, 3.5.1.16 - E ko:K00930,ko:K01438,ko:K05828,ko:K05831 ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase activity
HBCFODLC_02399 6.78e-248 - 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HBCFODLC_02400 0.0 - - - E - - - DegT/DnrJ/EryC1/StrS aminotransferase family
HBCFODLC_02401 2.43e-151 - - - - - - - -
HBCFODLC_02402 5.13e-211 lysX_2 6.3.2.32 - HJ ko:K05844,ko:K14940 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko01000,ko03009 Belongs to the RimK family
HBCFODLC_02404 1.02e-201 - - - K - - - Helix-turn-helix XRE-family like proteins
HBCFODLC_02405 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HBCFODLC_02406 2.04e-97 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HBCFODLC_02407 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
HBCFODLC_02408 8.03e-203 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HBCFODLC_02409 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HBCFODLC_02410 7.18e-192 yxeH - - S - - - hydrolase
HBCFODLC_02411 4.31e-179 - - - - - - - -
HBCFODLC_02412 2.82e-236 - - - S - - - DUF218 domain
HBCFODLC_02413 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBCFODLC_02414 2.82e-196 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HBCFODLC_02415 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HBCFODLC_02416 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HBCFODLC_02417 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HBCFODLC_02418 5.67e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HBCFODLC_02419 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
HBCFODLC_02420 2.26e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HBCFODLC_02421 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
HBCFODLC_02422 1.06e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HBCFODLC_02423 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HBCFODLC_02424 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HBCFODLC_02425 1.28e-273 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
HBCFODLC_02426 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBCFODLC_02427 1.14e-92 - - - F - - - DNA mismatch repair protein MutT
HBCFODLC_02428 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
HBCFODLC_02429 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HBCFODLC_02430 4.65e-229 - - - - - - - -
HBCFODLC_02431 9.68e-291 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HBCFODLC_02432 2.35e-215 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HBCFODLC_02433 1.25e-194 - - - S - - - Psort location Cytoplasmic, score
HBCFODLC_02434 4.28e-263 - - - - - - - -
HBCFODLC_02435 7.22e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBCFODLC_02436 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
HBCFODLC_02437 4.21e-210 - - - GK - - - ROK family
HBCFODLC_02438 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_02439 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_02440 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
HBCFODLC_02441 9.68e-34 - - - - - - - -
HBCFODLC_02442 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_02443 6.61e-167 - - - K - - - UbiC transcription regulator-associated domain protein
HBCFODLC_02444 2.01e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HBCFODLC_02445 7.76e-186 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HBCFODLC_02446 0.0 - - - L - - - DNA helicase
HBCFODLC_02447 4.23e-64 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
HBCFODLC_02448 3.64e-151 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_02449 2.75e-145 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_02450 5.04e-155 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_02451 3.26e-124 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_02452 1.49e-309 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HBCFODLC_02453 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HBCFODLC_02454 8.82e-32 - - - - - - - -
HBCFODLC_02455 1.93e-31 plnF - - - - - - -
HBCFODLC_02456 8.15e-167 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_02457 1.05e-173 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HBCFODLC_02458 2.48e-172 sppR - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HBCFODLC_02459 2.08e-301 plnB 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HBCFODLC_02460 1.9e-25 plnA - - - - - - -
HBCFODLC_02461 1.22e-36 - - - - - - - -
HBCFODLC_02462 2.08e-160 plnP - - S - - - CAAX protease self-immunity
HBCFODLC_02463 5.58e-291 - - - M - - - Glycosyl transferase family 2
HBCFODLC_02465 4.08e-39 - - - - - - - -
HBCFODLC_02466 8.53e-34 plnJ - - - - - - -
HBCFODLC_02467 1.97e-33 plnK - - - - - - -
HBCFODLC_02468 9.76e-153 - - - - - - - -
HBCFODLC_02469 6.24e-25 plnR - - - - - - -
HBCFODLC_02470 1.15e-43 - - - - - - - -
HBCFODLC_02471 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HBCFODLC_02472 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HBCFODLC_02473 8.38e-192 - - - S - - - hydrolase
HBCFODLC_02474 2.35e-212 - - - K - - - Transcriptional regulator
HBCFODLC_02475 4.15e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HBCFODLC_02476 9.52e-264 - - - EGP - - - Transporter, major facilitator family protein
HBCFODLC_02477 9.2e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HBCFODLC_02478 8.5e-55 - - - - - - - -
HBCFODLC_02479 5.12e-92 - - - S - - - Immunity protein 63
HBCFODLC_02480 2.05e-90 - - - - - - - -
HBCFODLC_02481 1.92e-64 - - - U - - - nuclease activity
HBCFODLC_02482 8.53e-28 - - - - - - - -
HBCFODLC_02483 3.31e-52 - - - - - - - -
HBCFODLC_02484 7.2e-61 - - - S - - - Enterocin A Immunity
HBCFODLC_02485 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HBCFODLC_02486 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_02487 2.66e-172 - - - - - - - -
HBCFODLC_02488 9.38e-139 pncA - - Q - - - Isochorismatase family
HBCFODLC_02491 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HBCFODLC_02492 5.25e-298 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HBCFODLC_02493 4.39e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HBCFODLC_02494 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HBCFODLC_02495 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HBCFODLC_02496 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HBCFODLC_02497 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HBCFODLC_02498 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HBCFODLC_02499 1.22e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HBCFODLC_02500 1.12e-246 ampC - - V - - - Beta-lactamase
HBCFODLC_02501 2.1e-41 - - - - - - - -
HBCFODLC_02502 6.63e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HBCFODLC_02503 1.33e-77 - - - - - - - -
HBCFODLC_02504 6.55e-183 - - - - - - - -
HBCFODLC_02505 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HBCFODLC_02506 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_02507 5.63e-89 yxeA - - S - - - Protein of unknown function (DUF1093)
HBCFODLC_02508 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
HBCFODLC_02509 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HBCFODLC_02510 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBCFODLC_02511 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HBCFODLC_02512 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HBCFODLC_02513 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HBCFODLC_02514 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HBCFODLC_02515 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HBCFODLC_02516 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HBCFODLC_02517 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HBCFODLC_02518 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HBCFODLC_02519 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HBCFODLC_02520 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HBCFODLC_02521 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HBCFODLC_02522 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HBCFODLC_02523 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HBCFODLC_02524 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HBCFODLC_02525 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HBCFODLC_02526 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HBCFODLC_02527 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HBCFODLC_02528 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HBCFODLC_02529 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HBCFODLC_02530 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HBCFODLC_02531 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HBCFODLC_02532 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HBCFODLC_02533 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HBCFODLC_02534 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HBCFODLC_02535 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HBCFODLC_02536 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HBCFODLC_02537 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HBCFODLC_02538 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HBCFODLC_02539 1.81e-150 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HBCFODLC_02540 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBCFODLC_02541 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBCFODLC_02542 4.05e-141 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02543 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HBCFODLC_02544 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HBCFODLC_02552 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HBCFODLC_02553 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
HBCFODLC_02554 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HBCFODLC_02555 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HBCFODLC_02556 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HBCFODLC_02557 1.7e-118 - - - K - - - Transcriptional regulator
HBCFODLC_02558 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HBCFODLC_02559 3.88e-198 - - - I - - - alpha/beta hydrolase fold
HBCFODLC_02560 2.05e-153 - - - I - - - phosphatase
HBCFODLC_02561 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HBCFODLC_02562 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
HBCFODLC_02563 4.6e-169 - - - S - - - Putative threonine/serine exporter
HBCFODLC_02564 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HBCFODLC_02565 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HBCFODLC_02566 1.36e-77 - - - - - - - -
HBCFODLC_02567 7.79e-112 - - - K - - - MerR HTH family regulatory protein
HBCFODLC_02568 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HBCFODLC_02569 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
HBCFODLC_02570 9.04e-179 - - - - - - - -
HBCFODLC_02571 5.63e-89 - - - - - - - -
HBCFODLC_02572 1.01e-100 - - - - - - - -
HBCFODLC_02573 1.98e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HBCFODLC_02574 9.5e-124 - - - - - - - -
HBCFODLC_02575 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBCFODLC_02576 7.68e-48 ynzC - - S - - - UPF0291 protein
HBCFODLC_02577 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HBCFODLC_02578 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HBCFODLC_02579 3.4e-177 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HBCFODLC_02580 1.02e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HBCFODLC_02581 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBCFODLC_02582 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HBCFODLC_02583 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HBCFODLC_02584 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HBCFODLC_02585 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HBCFODLC_02586 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HBCFODLC_02587 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBCFODLC_02588 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HBCFODLC_02589 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HBCFODLC_02590 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HBCFODLC_02591 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBCFODLC_02592 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HBCFODLC_02593 6.9e-279 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HBCFODLC_02594 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HBCFODLC_02595 3.28e-63 ylxQ - - J - - - ribosomal protein
HBCFODLC_02596 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HBCFODLC_02597 1.06e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HBCFODLC_02598 0.0 - - - G - - - Major Facilitator
HBCFODLC_02599 2.21e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HBCFODLC_02600 9.84e-123 - - - - - - - -
HBCFODLC_02601 4.94e-304 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HBCFODLC_02602 3.1e-248 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HBCFODLC_02603 1.45e-114 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HBCFODLC_02604 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBCFODLC_02605 1.12e-243 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HBCFODLC_02606 2.06e-170 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HBCFODLC_02607 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HBCFODLC_02608 1.72e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HBCFODLC_02609 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HBCFODLC_02610 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HBCFODLC_02612 1.59e-210 - - - K - - - Transcriptional regulator
HBCFODLC_02613 5.11e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HBCFODLC_02614 2.45e-213 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HBCFODLC_02615 2.45e-101 - - - K - - - Winged helix DNA-binding domain
HBCFODLC_02616 0.0 ycaM - - E - - - amino acid
HBCFODLC_02617 2.89e-165 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
HBCFODLC_02618 1.5e-44 - - - - - - - -
HBCFODLC_02619 1.87e-249 - - - V - - - Beta-lactamase
HBCFODLC_02620 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HBCFODLC_02621 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HBCFODLC_02622 8.93e-71 - - - S - - - Pfam:DUF59
HBCFODLC_02623 7.39e-224 ydhF - - S - - - Aldo keto reductase
HBCFODLC_02624 2.42e-127 - - - FG - - - HIT domain
HBCFODLC_02625 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HBCFODLC_02626 4.29e-101 - - - - - - - -
HBCFODLC_02627 1.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HBCFODLC_02628 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
HBCFODLC_02629 0.0 cadA - - P - - - P-type ATPase
HBCFODLC_02631 3.75e-161 - - - S - - - YjbR
HBCFODLC_02632 1.42e-171 epsB - - M - - - biosynthesis protein
HBCFODLC_02633 7.38e-167 ywqD - - D - - - Capsular exopolysaccharide family
HBCFODLC_02634 1.24e-186 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HBCFODLC_02635 3.4e-229 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HBCFODLC_02636 2.23e-164 tuaA - - M - - - Bacterial sugar transferase
HBCFODLC_02637 8.14e-264 cps4F - - M - - - Glycosyl transferases group 1
HBCFODLC_02638 2.1e-251 wefC - - M - - - Stealth protein CR2, conserved region 2
HBCFODLC_02640 8.59e-181 - - - L - - - Belongs to the 'phage' integrase family
HBCFODLC_02641 1.28e-51 - - - - - - - -
HBCFODLC_02642 9.28e-58 - - - - - - - -
HBCFODLC_02643 1.27e-109 - - - K - - - MarR family
HBCFODLC_02644 0.0 - - - D - - - nuclear chromosome segregation
HBCFODLC_02645 0.0 inlJ - - M - - - MucBP domain
HBCFODLC_02646 6.58e-24 - - - - - - - -
HBCFODLC_02647 3.26e-24 - - - - - - - -
HBCFODLC_02648 1.56e-22 - - - - - - - -
HBCFODLC_02649 1.07e-26 - - - - - - - -
HBCFODLC_02650 9.35e-24 - - - - - - - -
HBCFODLC_02651 9.35e-24 - - - - - - - -
HBCFODLC_02652 9.35e-24 - - - - - - - -
HBCFODLC_02653 2.16e-26 - - - - - - - -
HBCFODLC_02654 4.63e-24 - - - - - - - -
HBCFODLC_02655 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
HBCFODLC_02656 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HBCFODLC_02657 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_02658 2.1e-33 - - - - - - - -
HBCFODLC_02659 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HBCFODLC_02660 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HBCFODLC_02661 1.83e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HBCFODLC_02662 0.0 yclK - - T - - - Histidine kinase
HBCFODLC_02663 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HBCFODLC_02664 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HBCFODLC_02665 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HBCFODLC_02666 1.26e-218 - - - EG - - - EamA-like transporter family
HBCFODLC_02668 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
HBCFODLC_02669 1.31e-64 - - - - - - - -
HBCFODLC_02670 2.39e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
HBCFODLC_02671 8.05e-178 - - - F - - - NUDIX domain
HBCFODLC_02672 2.68e-32 - - - - - - - -
HBCFODLC_02674 8.51e-209 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HBCFODLC_02675 1.05e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
HBCFODLC_02676 4.17e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HBCFODLC_02677 2.29e-48 - - - - - - - -
HBCFODLC_02678 1.11e-45 - - - - - - - -
HBCFODLC_02679 4.86e-279 - - - T - - - diguanylate cyclase
HBCFODLC_02680 0.0 - - - S - - - ABC transporter, ATP-binding protein
HBCFODLC_02681 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
HBCFODLC_02682 1.1e-277 pbpX2 - - V - - - Beta-lactamase
HBCFODLC_02683 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HBCFODLC_02684 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBCFODLC_02685 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HBCFODLC_02686 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBCFODLC_02687 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HBCFODLC_02688 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HBCFODLC_02689 1.23e-50 - - - L - - - Transposase and inactivated derivatives
HBCFODLC_02690 8.56e-67 - - - L - - - Helix-turn-helix domain
HBCFODLC_02691 9.95e-108 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBCFODLC_02692 9.2e-62 - - - - - - - -
HBCFODLC_02693 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HBCFODLC_02694 5.54e-244 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBCFODLC_02695 5.97e-210 - - - S - - - Uncharacterised protein, DegV family COG1307
HBCFODLC_02696 7.45e-296 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HBCFODLC_02697 3.01e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HBCFODLC_02698 3.77e-214 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HBCFODLC_02699 2.79e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_02700 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HBCFODLC_02701 1.38e-180 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_02702 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HBCFODLC_02703 2.43e-205 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HBCFODLC_02704 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
HBCFODLC_02705 1.74e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HBCFODLC_02706 3.29e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HBCFODLC_02707 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
HBCFODLC_02708 6.12e-78 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HBCFODLC_02709 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HBCFODLC_02710 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HBCFODLC_02711 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HBCFODLC_02712 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HBCFODLC_02713 9.49e-300 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HBCFODLC_02714 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HBCFODLC_02715 1.39e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HBCFODLC_02716 1.12e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
HBCFODLC_02717 3.72e-283 ysaA - - V - - - RDD family
HBCFODLC_02718 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HBCFODLC_02719 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
HBCFODLC_02720 1.16e-118 rmeB - - K - - - transcriptional regulator, MerR family
HBCFODLC_02721 2.49e-190 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HBCFODLC_02722 4.54e-126 - - - J - - - glyoxalase III activity
HBCFODLC_02723 1.44e-256 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBCFODLC_02724 1.03e-240 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HBCFODLC_02725 1.45e-46 - - - - - - - -
HBCFODLC_02726 3.1e-144 - - - S - - - Protein of unknown function (DUF1211)
HBCFODLC_02727 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HBCFODLC_02728 3.06e-202 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBCFODLC_02729 9.69e-317 - - - G - - - PFAM glycoside hydrolase family 39
HBCFODLC_02730 1.37e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HBCFODLC_02731 1.39e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HBCFODLC_02732 1.3e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HBCFODLC_02733 1.16e-23 - - - L ko:K07497 - ko00000 hmm pf00665
HBCFODLC_02734 8.3e-115 - - - L ko:K07497 - ko00000 hmm pf00665
HBCFODLC_02735 1.12e-20 - - - L ko:K07497 - ko00000 hmm pf00665
HBCFODLC_02736 6.51e-62 - - - L - - - Helix-turn-helix domain
HBCFODLC_02738 1.04e-267 - - - K - - - IrrE N-terminal-like domain
HBCFODLC_02739 1.15e-160 - - - - - - - -
HBCFODLC_02740 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
HBCFODLC_02741 4.1e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
HBCFODLC_02742 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
HBCFODLC_02743 1.49e-252 - - - M - - - MucBP domain
HBCFODLC_02765 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HBCFODLC_02766 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
HBCFODLC_02767 1.24e-11 - - - S - - - Immunity protein 22
HBCFODLC_02768 3.83e-230 - - - - - - - -
HBCFODLC_02770 1.21e-54 - - - - - - - -
HBCFODLC_02771 1.4e-53 - - - - - - - -
HBCFODLC_02772 2.23e-97 - - - - - - - -
HBCFODLC_02773 8.51e-130 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
HBCFODLC_02775 2.21e-226 - - - S - - - Glycosyltransferase like family 2
HBCFODLC_02776 6.24e-269 - - - M - - - Glycosyl transferases group 1
HBCFODLC_02778 5.1e-220 - - - S - - - transferase activity, transferring acyl groups other than amino-acyl groups
HBCFODLC_02779 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
HBCFODLC_02780 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBCFODLC_02781 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBCFODLC_02782 3.81e-18 - - - - - - - -
HBCFODLC_02783 1.29e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBCFODLC_02784 3.91e-211 fbpA - - K - - - Domain of unknown function (DUF814)
HBCFODLC_02785 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
HBCFODLC_02786 6.33e-46 - - - - - - - -
HBCFODLC_02787 1.51e-190 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HBCFODLC_02788 6.7e-148 pgm1 - - G - - - phosphoglycerate mutase
HBCFODLC_02789 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HBCFODLC_02790 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBCFODLC_02791 5.57e-104 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HBCFODLC_02792 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HBCFODLC_02793 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HBCFODLC_02794 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HBCFODLC_02796 5.99e-213 mleR - - K - - - LysR substrate binding domain
HBCFODLC_02797 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HBCFODLC_02798 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HBCFODLC_02799 9.92e-212 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HBCFODLC_02800 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HBCFODLC_02801 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HBCFODLC_02802 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HBCFODLC_02803 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HBCFODLC_02804 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HBCFODLC_02805 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HBCFODLC_02806 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
HBCFODLC_02807 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HBCFODLC_02808 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HBCFODLC_02809 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
HBCFODLC_02810 6.12e-192 malA - - S - - - maltodextrose utilization protein MalA
HBCFODLC_02811 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HBCFODLC_02812 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HBCFODLC_02813 1.99e-300 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HBCFODLC_02814 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HBCFODLC_02815 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
HBCFODLC_02816 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HBCFODLC_02817 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HBCFODLC_02818 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HBCFODLC_02819 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HBCFODLC_02820 9.52e-240 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HBCFODLC_02821 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
HBCFODLC_02822 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02824 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
HBCFODLC_02825 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
HBCFODLC_02826 9.77e-152 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HBCFODLC_02827 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HBCFODLC_02828 1.04e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_02829 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HBCFODLC_02830 3.37e-115 - - - - - - - -
HBCFODLC_02831 1.15e-193 - - - - - - - -
HBCFODLC_02832 1.14e-184 - - - - - - - -
HBCFODLC_02833 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
HBCFODLC_02834 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HBCFODLC_02835 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HBCFODLC_02836 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_02837 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HBCFODLC_02838 6.49e-268 - - - C - - - Oxidoreductase
HBCFODLC_02839 0.0 - - - - - - - -
HBCFODLC_02840 4.03e-132 - - - - - - - -
HBCFODLC_02841 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HBCFODLC_02842 1.92e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
HBCFODLC_02843 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
HBCFODLC_02844 2.16e-204 morA - - S - - - reductase
HBCFODLC_02846 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HBCFODLC_02847 2.8e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HBCFODLC_02848 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HBCFODLC_02849 5.42e-89 - - - K - - - LytTr DNA-binding domain
HBCFODLC_02850 1.35e-106 - - - S - - - Protein of unknown function (DUF3021)
HBCFODLC_02851 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HBCFODLC_02852 9.35e-101 - - - K - - - Transcriptional regulator
HBCFODLC_02853 3.61e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HBCFODLC_02854 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HBCFODLC_02855 8.08e-185 - - - F - - - Phosphorylase superfamily
HBCFODLC_02856 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HBCFODLC_02857 5.08e-192 - - - I - - - Alpha/beta hydrolase family
HBCFODLC_02858 3.8e-161 - - - - - - - -
HBCFODLC_02859 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HBCFODLC_02860 2.14e-110 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HBCFODLC_02861 0.0 - - - L - - - HIRAN domain
HBCFODLC_02862 7.45e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HBCFODLC_02863 9.14e-265 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HBCFODLC_02864 7.15e-148 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HBCFODLC_02865 7.44e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HBCFODLC_02866 2.27e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HBCFODLC_02867 3.02e-228 - - - C - - - Zinc-binding dehydrogenase
HBCFODLC_02868 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
HBCFODLC_02869 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HBCFODLC_02870 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
HBCFODLC_02871 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HBCFODLC_02872 1.86e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
HBCFODLC_02873 3.91e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
HBCFODLC_02874 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
HBCFODLC_02875 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HBCFODLC_02876 8.38e-193 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HBCFODLC_02877 7.41e-167 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HBCFODLC_02878 1.67e-54 - - - - - - - -
HBCFODLC_02879 2.92e-186 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HBCFODLC_02880 4.07e-05 - - - - - - - -
HBCFODLC_02881 5.9e-181 - - - - - - - -
HBCFODLC_02882 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HBCFODLC_02883 2.38e-99 - - - - - - - -
HBCFODLC_02884 2.71e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HBCFODLC_02885 5.17e-219 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HBCFODLC_02886 3.61e-303 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HBCFODLC_02887 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HBCFODLC_02888 1.77e-236 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HBCFODLC_02889 2.41e-163 - - - S - - - DJ-1/PfpI family
HBCFODLC_02890 7.65e-121 yfbM - - K - - - FR47-like protein
HBCFODLC_02891 1.56e-197 - - - EG - - - EamA-like transporter family
HBCFODLC_02892 2.81e-164 - - - S - - - Protein of unknown function
HBCFODLC_02893 0.0 fusA1 - - J - - - elongation factor G
HBCFODLC_02894 8.1e-153 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBCFODLC_02895 6.07e-223 - - - K - - - WYL domain
HBCFODLC_02896 3.06e-165 - - - F - - - glutamine amidotransferase
HBCFODLC_02897 1.65e-106 - - - S - - - ASCH
HBCFODLC_02898 1.21e-19 - - - Q - - - 4-hydroxyphenylacetate
HBCFODLC_02899 5.94e-301 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
HBCFODLC_02900 1.68e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HBCFODLC_02901 0.0 - - - S - - - Putative threonine/serine exporter
HBCFODLC_02902 2.28e-250 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HBCFODLC_02903 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HBCFODLC_02904 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
HBCFODLC_02905 5.07e-157 ydgI - - C - - - Nitroreductase family
HBCFODLC_02906 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
HBCFODLC_02907 4.06e-211 - - - S - - - KR domain
HBCFODLC_02908 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBCFODLC_02909 2.49e-95 - - - C - - - FMN binding
HBCFODLC_02910 1.46e-204 - - - K - - - LysR family
HBCFODLC_02911 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HBCFODLC_02912 0.0 - - - C - - - FMN_bind
HBCFODLC_02913 2.96e-204 - - - S - - - Protein of unknown function (DUF2785)
HBCFODLC_02914 9.45e-152 - - - S - - - Elongation factor G-binding protein, N-terminal
HBCFODLC_02915 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
HBCFODLC_02916 8.12e-158 pnb - - C - - - nitroreductase
HBCFODLC_02917 5.97e-157 ung2 - - L - - - Uracil-DNA glycosylase
HBCFODLC_02918 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
HBCFODLC_02919 5.12e-126 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02920 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HBCFODLC_02921 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HBCFODLC_02922 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HBCFODLC_02923 3.54e-195 yycI - - S - - - YycH protein
HBCFODLC_02924 3.55e-313 yycH - - S - - - YycH protein
HBCFODLC_02925 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HBCFODLC_02926 1.56e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HBCFODLC_02928 2.54e-50 - - - - - - - -
HBCFODLC_02929 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
HBCFODLC_02930 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HBCFODLC_02931 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HBCFODLC_02932 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HBCFODLC_02933 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
HBCFODLC_02935 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HBCFODLC_02936 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HBCFODLC_02937 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HBCFODLC_02938 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HBCFODLC_02939 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HBCFODLC_02940 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HBCFODLC_02942 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HBCFODLC_02944 3.25e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HBCFODLC_02945 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HBCFODLC_02946 4.96e-289 yttB - - EGP - - - Major Facilitator
HBCFODLC_02947 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HBCFODLC_02948 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HBCFODLC_02949 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HBCFODLC_02950 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HBCFODLC_02951 5.03e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HBCFODLC_02952 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HBCFODLC_02953 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBCFODLC_02954 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBCFODLC_02955 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HBCFODLC_02956 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HBCFODLC_02957 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HBCFODLC_02958 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HBCFODLC_02959 4.5e-149 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBCFODLC_02960 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
HBCFODLC_02961 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HBCFODLC_02962 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
HBCFODLC_02963 4.93e-286 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_02964 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_02965 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HBCFODLC_02966 6.76e-73 - - - - - - - -
HBCFODLC_02967 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HBCFODLC_02968 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
HBCFODLC_02969 6.93e-139 - - - S - - - WxL domain surface cell wall-binding
HBCFODLC_02970 3.36e-248 - - - S - - - Fn3-like domain
HBCFODLC_02971 1.16e-80 - - - - - - - -
HBCFODLC_02972 0.0 - - - - - - - -
HBCFODLC_02973 5.19e-309 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HBCFODLC_02974 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
HBCFODLC_02975 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HBCFODLC_02976 3.39e-138 - - - - - - - -
HBCFODLC_02977 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
HBCFODLC_02978 1.05e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HBCFODLC_02979 1.86e-287 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HBCFODLC_02980 1.69e-87 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HBCFODLC_02981 0.0 - - - S - - - membrane
HBCFODLC_02982 2.52e-93 - - - S - - - NUDIX domain
HBCFODLC_02983 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HBCFODLC_02984 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
HBCFODLC_02985 4.08e-101 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
HBCFODLC_02986 3.8e-130 - - - - - - - -
HBCFODLC_02987 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HBCFODLC_02988 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
HBCFODLC_02989 6.59e-227 - - - K - - - LysR substrate binding domain
HBCFODLC_02990 1.77e-235 - - - M - - - Peptidase family S41
HBCFODLC_02991 2.44e-281 - - - - - - - -
HBCFODLC_02992 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HBCFODLC_02993 0.0 yhaN - - L - - - AAA domain
HBCFODLC_02994 4.47e-296 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HBCFODLC_02995 3.47e-71 yheA - - S - - - Belongs to the UPF0342 family
HBCFODLC_02996 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HBCFODLC_02997 2.43e-18 - - - - - - - -
HBCFODLC_02998 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HBCFODLC_02999 9.65e-272 arcT - - E - - - Aminotransferase
HBCFODLC_03000 1.98e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
HBCFODLC_03001 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
HBCFODLC_03002 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBCFODLC_03003 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
HBCFODLC_03004 6.6e-276 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
HBCFODLC_03005 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_03006 1.82e-311 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBCFODLC_03007 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HBCFODLC_03008 5.81e-69 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HBCFODLC_03009 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
HBCFODLC_03010 0.0 celR - - K - - - PRD domain
HBCFODLC_03011 5.83e-73 - - - - - - - -
HBCFODLC_03012 6.9e-69 - - - - - - - -
HBCFODLC_03013 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HBCFODLC_03014 2.91e-109 - - - - - - - -
HBCFODLC_03015 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HBCFODLC_03016 1.21e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
HBCFODLC_03019 1.79e-42 - - - - - - - -
HBCFODLC_03020 2.69e-316 dinF - - V - - - MatE
HBCFODLC_03021 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
HBCFODLC_03022 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
HBCFODLC_03023 6.91e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
HBCFODLC_03024 2.24e-146 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HBCFODLC_03025 8.91e-293 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HBCFODLC_03026 0.0 - - - S - - - Protein conserved in bacteria
HBCFODLC_03027 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HBCFODLC_03028 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HBCFODLC_03029 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
HBCFODLC_03030 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
HBCFODLC_03031 3.89e-237 - - - - - - - -
HBCFODLC_03032 9.03e-16 - - - - - - - -
HBCFODLC_03033 9.76e-93 - - - - - - - -
HBCFODLC_03036 0.0 uvrA2 - - L - - - ABC transporter
HBCFODLC_03037 7.12e-62 - - - - - - - -
HBCFODLC_03038 8.82e-119 - - - - - - - -
HBCFODLC_03039 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HBCFODLC_03040 6.71e-142 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HBCFODLC_03041 4.56e-78 - - - - - - - -
HBCFODLC_03042 5.37e-74 - - - - - - - -
HBCFODLC_03043 3.14e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HBCFODLC_03044 2.17e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HBCFODLC_03045 7.83e-140 - - - - - - - -
HBCFODLC_03046 6.89e-192 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HBCFODLC_03047 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
HBCFODLC_03048 4.7e-283 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HBCFODLC_03049 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBCFODLC_03050 3.59e-26 - - - - - - - -
HBCFODLC_03051 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
HBCFODLC_03052 9.9e-209 mleR - - K - - - LysR family
HBCFODLC_03053 1.29e-148 - - - GM - - - NAD(P)H-binding
HBCFODLC_03054 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
HBCFODLC_03055 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HBCFODLC_03056 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HBCFODLC_03057 9.44e-219 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
HBCFODLC_03058 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HBCFODLC_03059 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HBCFODLC_03060 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HBCFODLC_03061 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HBCFODLC_03062 3.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HBCFODLC_03063 2.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HBCFODLC_03064 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HBCFODLC_03065 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HBCFODLC_03066 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
HBCFODLC_03067 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HBCFODLC_03068 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
HBCFODLC_03069 1.64e-208 - - - GM - - - NmrA-like family
HBCFODLC_03070 1.25e-199 - - - T - - - EAL domain
HBCFODLC_03071 1.85e-121 - - - - - - - -
HBCFODLC_03072 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HBCFODLC_03073 7.21e-164 - - - E - - - Methionine synthase
HBCFODLC_03074 2.43e-283 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HBCFODLC_03075 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HBCFODLC_03076 9.25e-134 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBCFODLC_03077 2.65e-246 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HBCFODLC_03078 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HBCFODLC_03079 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBCFODLC_03080 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBCFODLC_03081 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBCFODLC_03082 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HBCFODLC_03083 1e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBCFODLC_03084 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HBCFODLC_03085 1.33e-312 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HBCFODLC_03086 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
HBCFODLC_03087 4.94e-244 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
HBCFODLC_03088 3.02e-191 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HBCFODLC_03089 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HBCFODLC_03090 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HBCFODLC_03091 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HBCFODLC_03092 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_03093 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HBCFODLC_03094 4.76e-56 - - - - - - - -
HBCFODLC_03095 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
HBCFODLC_03096 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HBCFODLC_03097 3.41e-190 - - - - - - - -
HBCFODLC_03098 2.7e-104 usp5 - - T - - - universal stress protein
HBCFODLC_03099 1.08e-47 - - - - - - - -
HBCFODLC_03100 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
HBCFODLC_03101 1.76e-114 - - - - - - - -
HBCFODLC_03102 1.02e-67 - - - - - - - -
HBCFODLC_03103 4.79e-13 - - - - - - - -
HBCFODLC_03104 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HBCFODLC_03105 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
HBCFODLC_03106 1.52e-151 - - - - - - - -
HBCFODLC_03107 1.21e-69 - - - - - - - -
HBCFODLC_03109 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HBCFODLC_03110 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HBCFODLC_03111 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HBCFODLC_03112 2.96e-41 - - - S - - - Pentapeptide repeats (8 copies)
HBCFODLC_03113 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HBCFODLC_03114 1.13e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HBCFODLC_03115 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
HBCFODLC_03116 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HBCFODLC_03117 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
HBCFODLC_03118 6.01e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HBCFODLC_03119 2.78e-297 - - - S - - - Sterol carrier protein domain
HBCFODLC_03120 5.78e-288 - - - EGP - - - Transmembrane secretion effector
HBCFODLC_03121 3.74e-115 yrxA - - S ko:K07105 - ko00000 3H domain
HBCFODLC_03122 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HBCFODLC_03123 2.13e-152 - - - K - - - Transcriptional regulator
HBCFODLC_03124 1.19e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HBCFODLC_03125 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HBCFODLC_03126 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HBCFODLC_03127 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_03128 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HBCFODLC_03129 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
HBCFODLC_03130 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HBCFODLC_03131 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
HBCFODLC_03132 1.4e-181 epsV - - S - - - glycosyl transferase family 2
HBCFODLC_03133 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
HBCFODLC_03134 4.6e-108 - - - - - - - -
HBCFODLC_03135 5.06e-196 - - - S - - - hydrolase
HBCFODLC_03136 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBCFODLC_03137 2.8e-204 - - - EG - - - EamA-like transporter family
HBCFODLC_03138 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HBCFODLC_03139 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HBCFODLC_03140 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
HBCFODLC_03141 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HBCFODLC_03142 0.0 - - - M - - - Domain of unknown function (DUF5011)
HBCFODLC_03143 1.46e-55 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)