ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EHHPBMKL_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHHPBMKL_00002 8.47e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EHHPBMKL_00003 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
EHHPBMKL_00004 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHHPBMKL_00005 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
EHHPBMKL_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHHPBMKL_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHHPBMKL_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHHPBMKL_00011 8.24e-234 yaaC - - S - - - YaaC-like Protein
EHHPBMKL_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EHHPBMKL_00013 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHHPBMKL_00014 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EHHPBMKL_00015 2.86e-139 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EHHPBMKL_00016 1.3e-284 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHHPBMKL_00017 1.9e-257 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EHHPBMKL_00019 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
EHHPBMKL_00020 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
EHHPBMKL_00021 5.59e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
EHHPBMKL_00022 1.44e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
EHHPBMKL_00023 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EHHPBMKL_00024 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHHPBMKL_00025 9.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHHPBMKL_00026 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHHPBMKL_00027 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
EHHPBMKL_00028 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
EHHPBMKL_00029 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHHPBMKL_00032 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
EHHPBMKL_00033 7.19e-137 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EHHPBMKL_00034 2.32e-242 yaaN - - P - - - Belongs to the TelA family
EHHPBMKL_00035 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
EHHPBMKL_00036 1.9e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHHPBMKL_00037 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
EHHPBMKL_00038 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
EHHPBMKL_00039 4.41e-228 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EHHPBMKL_00040 9e-189 yaaT - - S - - - stage 0 sporulation protein
EHHPBMKL_00041 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
EHHPBMKL_00042 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
EHHPBMKL_00043 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
EHHPBMKL_00044 1.65e-209 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHHPBMKL_00045 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
EHHPBMKL_00046 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHHPBMKL_00047 1.02e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
EHHPBMKL_00048 3.23e-306 yabE - - T - - - protein conserved in bacteria
EHHPBMKL_00049 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EHHPBMKL_00050 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EHHPBMKL_00051 6.71e-208 yabG - - S ko:K06436 - ko00000 peptidase
EHHPBMKL_00052 3.08e-52 veg - - S - - - protein conserved in bacteria
EHHPBMKL_00053 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
EHHPBMKL_00054 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHHPBMKL_00055 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EHHPBMKL_00056 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
EHHPBMKL_00057 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EHHPBMKL_00058 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHHPBMKL_00059 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHHPBMKL_00060 3.57e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHHPBMKL_00061 1.74e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EHHPBMKL_00062 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
EHHPBMKL_00063 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHHPBMKL_00064 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
EHHPBMKL_00065 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHPBMKL_00066 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EHHPBMKL_00067 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EHHPBMKL_00068 5.47e-66 yabP - - S - - - Sporulation protein YabP
EHHPBMKL_00069 1.95e-133 yabQ - - S - - - spore cortex biosynthesis protein
EHHPBMKL_00070 6.94e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EHHPBMKL_00071 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EHHPBMKL_00074 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
EHHPBMKL_00075 5.38e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EHHPBMKL_00076 3.3e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
EHHPBMKL_00077 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EHHPBMKL_00078 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
EHHPBMKL_00079 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHHPBMKL_00080 8.14e-178 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EHHPBMKL_00081 1.3e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHHPBMKL_00082 2.79e-198 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
EHHPBMKL_00083 2.09e-215 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EHHPBMKL_00084 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHHPBMKL_00085 2.97e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
EHHPBMKL_00086 2.83e-206 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
EHHPBMKL_00087 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHHPBMKL_00088 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHHPBMKL_00089 3.34e-117 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHHPBMKL_00090 8.67e-40 yazB - - K - - - transcriptional
EHHPBMKL_00091 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHHPBMKL_00092 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EHHPBMKL_00093 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHHPBMKL_00103 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHHPBMKL_00104 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EHHPBMKL_00105 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
EHHPBMKL_00106 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EHHPBMKL_00107 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
EHHPBMKL_00108 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHHPBMKL_00109 7.66e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EHHPBMKL_00110 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
EHHPBMKL_00111 2.38e-158 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EHHPBMKL_00112 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EHHPBMKL_00113 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHHPBMKL_00114 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
EHHPBMKL_00115 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EHHPBMKL_00116 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EHHPBMKL_00117 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHHPBMKL_00118 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
EHHPBMKL_00119 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
EHHPBMKL_00120 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EHHPBMKL_00121 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EHHPBMKL_00122 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHHPBMKL_00123 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EHHPBMKL_00124 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHHPBMKL_00125 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EHHPBMKL_00126 1.2e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
EHHPBMKL_00127 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHHPBMKL_00128 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHHPBMKL_00129 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
EHHPBMKL_00130 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EHHPBMKL_00131 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EHHPBMKL_00132 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHHPBMKL_00133 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHHPBMKL_00134 2.33e-239 ybaC - - S - - - Alpha/beta hydrolase family
EHHPBMKL_00135 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EHHPBMKL_00136 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHHPBMKL_00137 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EHHPBMKL_00138 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EHHPBMKL_00139 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHHPBMKL_00140 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHHPBMKL_00141 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHHPBMKL_00142 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHHPBMKL_00143 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EHHPBMKL_00144 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EHHPBMKL_00145 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHHPBMKL_00146 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHHPBMKL_00147 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHHPBMKL_00148 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHHPBMKL_00149 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHHPBMKL_00150 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHHPBMKL_00151 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHHPBMKL_00152 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EHHPBMKL_00153 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EHHPBMKL_00154 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EHHPBMKL_00155 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EHHPBMKL_00156 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EHHPBMKL_00157 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EHHPBMKL_00158 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EHHPBMKL_00159 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHHPBMKL_00160 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EHHPBMKL_00161 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHHPBMKL_00162 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHHPBMKL_00163 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHHPBMKL_00164 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EHHPBMKL_00165 1.45e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHHPBMKL_00166 2.09e-191 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHHPBMKL_00167 7.93e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHHPBMKL_00168 3.56e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EHHPBMKL_00169 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHHPBMKL_00170 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EHHPBMKL_00171 1.76e-185 ybaJ - - Q - - - Methyltransferase domain
EHHPBMKL_00172 9.4e-110 yizA - - S - - - Damage-inducible protein DinB
EHHPBMKL_00173 9.25e-103 ybaK - - S - - - Protein of unknown function (DUF2521)
EHHPBMKL_00174 2.31e-172 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EHHPBMKL_00175 9e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EHHPBMKL_00176 1.95e-102 gerD - - - ko:K06294 - ko00000 -
EHHPBMKL_00177 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
EHHPBMKL_00178 6.38e-183 pdaB - - G - - - Polysaccharide deacetylase
EHHPBMKL_00179 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHHPBMKL_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHHPBMKL_00186 3.31e-281 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
EHHPBMKL_00187 1.22e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHHPBMKL_00188 7.74e-231 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
EHHPBMKL_00189 3.13e-253 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EHHPBMKL_00190 2.62e-286 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EHHPBMKL_00191 1.08e-222 ybaS - - S - - - Na -dependent transporter
EHHPBMKL_00192 1.35e-143 ybbA - - S ko:K07017 - ko00000 Putative esterase
EHHPBMKL_00193 1.43e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHPBMKL_00194 1.8e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHPBMKL_00195 1.21e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
EHHPBMKL_00196 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
EHHPBMKL_00197 2.61e-299 ybbC - - S - - - protein conserved in bacteria
EHHPBMKL_00198 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
EHHPBMKL_00199 2.56e-308 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
EHHPBMKL_00200 5.86e-310 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_00201 3.84e-207 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHHPBMKL_00202 7.13e-110 ybbJ - - J - - - acetyltransferase
EHHPBMKL_00203 1.93e-101 ybbK - - S - - - Protein of unknown function (DUF523)
EHHPBMKL_00209 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHHPBMKL_00210 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EHHPBMKL_00211 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHHPBMKL_00212 7.18e-291 ybbR - - S - - - protein conserved in bacteria
EHHPBMKL_00213 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHHPBMKL_00214 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EHHPBMKL_00215 2.14e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EHHPBMKL_00216 1.42e-138 - - - S - - - ABC-2 family transporter protein
EHHPBMKL_00217 8.72e-163 - - - T ko:K11630 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_00218 2.32e-235 - - - T ko:K19168 - ko00000,ko02048 Histidine kinase
EHHPBMKL_00219 6.57e-176 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_00220 0.0 - - - V ko:K02004,ko:K11632 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EHHPBMKL_00221 4.5e-15 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHHPBMKL_00222 1.03e-206 dkgB - - S - - - Aldo/keto reductase family
EHHPBMKL_00223 6.05e-135 yxaC - - M - - - effector of murein hydrolase
EHHPBMKL_00224 9.9e-68 - - - S ko:K06518 - ko00000,ko02000 LrgA family
EHHPBMKL_00225 5.62e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHHPBMKL_00227 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHHPBMKL_00228 1.07e-118 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EHHPBMKL_00229 2.38e-253 - - - T - - - COG4585 Signal transduction histidine kinase
EHHPBMKL_00230 2.04e-141 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
EHHPBMKL_00231 6.21e-214 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
EHHPBMKL_00232 3.18e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EHHPBMKL_00233 1.32e-252 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EHHPBMKL_00234 2.34e-35 - - - - - - - -
EHHPBMKL_00235 6.08e-102 - - - S - - - Domain of unknown function (DUF4879)
EHHPBMKL_00236 1.01e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
EHHPBMKL_00237 4.16e-143 yqeB - - - - - - -
EHHPBMKL_00238 7.84e-55 ybyB - - - - - - -
EHHPBMKL_00239 0.0 ybeC - - E - - - amino acid
EHHPBMKL_00240 5.3e-62 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EHHPBMKL_00242 6.28e-23 - - - S - - - Protein of unknown function (DUF2651)
EHHPBMKL_00243 8.18e-211 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
EHHPBMKL_00244 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
EHHPBMKL_00245 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
EHHPBMKL_00246 1.66e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
EHHPBMKL_00248 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
EHHPBMKL_00249 1.14e-25 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
EHHPBMKL_00250 8.96e-67 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
EHHPBMKL_00252 4.73e-176 draG - - O - - - ADP-ribosylglycohydrolase
EHHPBMKL_00253 2.1e-71 - - - M - - - nucleic acid phosphodiester bond hydrolysis
EHHPBMKL_00254 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
EHHPBMKL_00255 8.67e-255 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
EHHPBMKL_00256 1.87e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHHPBMKL_00257 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHHPBMKL_00258 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
EHHPBMKL_00259 7.49e-195 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EHHPBMKL_00260 8.67e-55 ybfN - - - - - - -
EHHPBMKL_00261 5.76e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
EHHPBMKL_00262 1.17e-271 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHHPBMKL_00263 8.33e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EHHPBMKL_00264 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHHPBMKL_00265 1.69e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
EHHPBMKL_00266 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EHHPBMKL_00267 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EHHPBMKL_00268 1.26e-278 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_00269 5.81e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
EHHPBMKL_00270 2.46e-08 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
EHHPBMKL_00271 4.85e-35 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
EHHPBMKL_00272 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHHPBMKL_00273 9.49e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
EHHPBMKL_00274 2.06e-233 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EHHPBMKL_00275 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
EHHPBMKL_00276 2.56e-72 ydfQ - - CO - - - Thioredoxin
EHHPBMKL_00277 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
EHHPBMKL_00278 1.44e-99 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
EHHPBMKL_00279 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
EHHPBMKL_00280 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EHHPBMKL_00281 4.24e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHHPBMKL_00282 4.68e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHHPBMKL_00283 1.92e-263 ycbU - - E - - - Selenocysteine lyase
EHHPBMKL_00284 1.68e-311 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
EHHPBMKL_00285 1.04e-128 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EHHPBMKL_00286 1.8e-250 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EHHPBMKL_00287 3.29e-147 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHHPBMKL_00288 9.7e-252 yccF - - K ko:K07039 - ko00000 SEC-C motif
EHHPBMKL_00289 6.12e-69 yccK - - C - - - Aldo keto reductase
EHHPBMKL_00290 9e-129 yccK - - C - - - Aldo keto reductase
EHHPBMKL_00291 6.27e-224 ycdA - - S - - - Domain of unknown function (DUF5105)
EHHPBMKL_00292 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHHPBMKL_00293 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHHPBMKL_00294 1.79e-121 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EHHPBMKL_00295 5.77e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
EHHPBMKL_00296 1.23e-178 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
EHHPBMKL_00297 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHHPBMKL_00298 3.64e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EHHPBMKL_00299 5.69e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EHHPBMKL_00300 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EHHPBMKL_00301 6.94e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHPBMKL_00302 4.06e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
EHHPBMKL_00303 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EHHPBMKL_00304 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EHHPBMKL_00305 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
EHHPBMKL_00306 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
EHHPBMKL_00307 4.74e-246 yceH - - P - - - Belongs to the TelA family
EHHPBMKL_00308 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
EHHPBMKL_00309 1.28e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
EHHPBMKL_00310 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EHHPBMKL_00311 2.85e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EHHPBMKL_00312 4.59e-270 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
EHHPBMKL_00313 8.03e-294 ycgA - - S - - - Membrane
EHHPBMKL_00314 4.41e-106 ycgB - - - - - - -
EHHPBMKL_00315 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
EHHPBMKL_00316 5.7e-32 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
EHHPBMKL_00317 6.6e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EHHPBMKL_00318 0.0 mdr - - EGP - - - the major facilitator superfamily
EHHPBMKL_00319 2.82e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHHPBMKL_00320 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
EHHPBMKL_00321 4.19e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EHHPBMKL_00322 1.15e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHHPBMKL_00323 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
EHHPBMKL_00324 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EHHPBMKL_00325 2.77e-06 - - - S - - - Bacillus cereus group antimicrobial protein
EHHPBMKL_00326 2.44e-141 tmrB - - S - - - AAA domain
EHHPBMKL_00327 5.46e-188 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
EHHPBMKL_00328 2.75e-287 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_00329 1.01e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHHPBMKL_00330 3.29e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
EHHPBMKL_00331 8.94e-183 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
EHHPBMKL_00332 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EHHPBMKL_00333 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EHHPBMKL_00334 6.34e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHHPBMKL_00335 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
EHHPBMKL_00336 3.33e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EHHPBMKL_00337 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EHHPBMKL_00338 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
EHHPBMKL_00339 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHHPBMKL_00340 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHHPBMKL_00341 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
EHHPBMKL_00342 4.05e-285 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EHHPBMKL_00343 1.73e-290 yciC - - S - - - GTPases (G3E family)
EHHPBMKL_00344 7.17e-281 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EHHPBMKL_00345 2.2e-95 yckC - - S - - - membrane
EHHPBMKL_00346 9.5e-68 - - - S - - - Protein of unknown function (DUF2680)
EHHPBMKL_00347 1.37e-43 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHHPBMKL_00348 6.79e-91 nin - - S - - - Competence protein J (ComJ)
EHHPBMKL_00349 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
EHHPBMKL_00350 1.22e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
EHHPBMKL_00351 5.21e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
EHHPBMKL_00352 4.1e-84 hxlR - - K - - - transcriptional
EHHPBMKL_00353 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_00354 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_00355 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
EHHPBMKL_00356 3.56e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
EHHPBMKL_00357 5.72e-316 - - - E - - - Aminotransferase class I and II
EHHPBMKL_00358 1.3e-167 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
EHHPBMKL_00359 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
EHHPBMKL_00360 3.24e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHHPBMKL_00361 3.53e-153 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHHPBMKL_00362 8.63e-121 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EHHPBMKL_00363 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
EHHPBMKL_00364 1.4e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EHHPBMKL_00365 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EHHPBMKL_00366 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
EHHPBMKL_00367 6.81e-100 yclD - - - - - - -
EHHPBMKL_00368 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
EHHPBMKL_00369 0.0 yclG - - M - - - Pectate lyase superfamily protein
EHHPBMKL_00371 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
EHHPBMKL_00372 2.82e-300 gerKC - - S ko:K06297 - ko00000 spore germination
EHHPBMKL_00373 6.22e-247 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
EHHPBMKL_00374 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHPBMKL_00375 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHPBMKL_00376 5.21e-182 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EHHPBMKL_00377 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHHPBMKL_00378 2.28e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_00379 2.3e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EHHPBMKL_00380 0.0 yxeQ - - S - - - MmgE/PrpD family
EHHPBMKL_00381 1.62e-158 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
EHHPBMKL_00382 6.53e-309 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
EHHPBMKL_00383 2.6e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_00384 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
EHHPBMKL_00385 1.2e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EHHPBMKL_00387 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHHPBMKL_00388 3.85e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHPBMKL_00389 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHPBMKL_00390 4.63e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_00391 3.24e-222 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
EHHPBMKL_00392 4.87e-314 ycnB - - EGP - - - the major facilitator superfamily
EHHPBMKL_00393 4.47e-197 ycnC - - K - - - Transcriptional regulator
EHHPBMKL_00394 1.97e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
EHHPBMKL_00395 8.02e-59 ycnE - - S - - - Monooxygenase
EHHPBMKL_00396 2.76e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EHHPBMKL_00397 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHHPBMKL_00398 2.17e-287 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHHPBMKL_00399 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHHPBMKL_00400 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
EHHPBMKL_00401 4.85e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHPBMKL_00402 2.05e-131 ycnI - - S - - - protein conserved in bacteria
EHHPBMKL_00403 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
EHHPBMKL_00404 4.26e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHHPBMKL_00405 1.59e-71 - - - - - - - -
EHHPBMKL_00406 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
EHHPBMKL_00407 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EHHPBMKL_00408 1.21e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
EHHPBMKL_00409 1.38e-85 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
EHHPBMKL_00411 1.1e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EHHPBMKL_00412 8.34e-179 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
EHHPBMKL_00413 2.66e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
EHHPBMKL_00414 1.4e-191 ycsI - - S - - - Belongs to the D-glutamate cyclase family
EHHPBMKL_00415 2.7e-174 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EHHPBMKL_00416 1.03e-241 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EHHPBMKL_00417 2.69e-166 kipR - - K - - - Transcriptional regulator
EHHPBMKL_00418 2.23e-149 ycsK - - E - - - anatomical structure formation involved in morphogenesis
EHHPBMKL_00420 5.95e-75 yczJ - - S - - - biosynthesis
EHHPBMKL_00421 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
EHHPBMKL_00422 2.57e-221 ycsN - - S - - - Oxidoreductase
EHHPBMKL_00423 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
EHHPBMKL_00424 0.0 ydaB - - IQ - - - acyl-CoA ligase
EHHPBMKL_00425 9.37e-208 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHPBMKL_00426 7.9e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
EHHPBMKL_00427 1.3e-145 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHHPBMKL_00428 1.83e-101 ydaG - - S - - - general stress protein
EHHPBMKL_00429 2.54e-176 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EHHPBMKL_00430 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
EHHPBMKL_00431 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EHHPBMKL_00432 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHHPBMKL_00433 1.34e-256 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
EHHPBMKL_00434 2.67e-189 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
EHHPBMKL_00435 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
EHHPBMKL_00436 2.16e-301 ydaM - - M - - - Glycosyl transferase family group 2
EHHPBMKL_00437 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
EHHPBMKL_00438 0.0 ydaO - - E - - - amino acid
EHHPBMKL_00439 1.04e-74 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EHHPBMKL_00440 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
EHHPBMKL_00441 1.02e-32 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EHHPBMKL_00442 2.27e-101 - - - - - - - -
EHHPBMKL_00444 1.65e-267 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
EHHPBMKL_00446 2.69e-12 - - - - - - - -
EHHPBMKL_00448 2.53e-114 - - - - - - - -
EHHPBMKL_00449 1.65e-127 - - - - - - - -
EHHPBMKL_00450 1.02e-32 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EHHPBMKL_00451 2.27e-101 - - - - - - - -
EHHPBMKL_00453 1.65e-267 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
EHHPBMKL_00455 2.69e-12 - - - - - - - -
EHHPBMKL_00457 2.53e-114 - - - - - - - -
EHHPBMKL_00458 1.65e-127 - - - - - - - -
EHHPBMKL_00459 1.02e-32 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EHHPBMKL_00460 2.27e-101 - - - - - - - -
EHHPBMKL_00462 1.65e-267 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
EHHPBMKL_00464 2.69e-12 - - - - - - - -
EHHPBMKL_00466 2.53e-114 - - - - - - - -
EHHPBMKL_00467 1.65e-127 - - - - - - - -
EHHPBMKL_00468 7.45e-54 - - - - - - - -
EHHPBMKL_00469 1.08e-287 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EHHPBMKL_00471 1.95e-45 ydaT - - - - - - -
EHHPBMKL_00472 5.32e-94 yvaD - - S - - - Family of unknown function (DUF5360)
EHHPBMKL_00473 2.87e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
EHHPBMKL_00474 1.09e-181 ydbA - - P - - - EcsC protein family
EHHPBMKL_00475 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
EHHPBMKL_00476 2.65e-78 ydbB - - G - - - Cupin domain
EHHPBMKL_00477 1.01e-79 ydbC - - S - - - Domain of unknown function (DUF4937
EHHPBMKL_00478 1.92e-198 ydbD - - P ko:K07217 - ko00000 Catalase
EHHPBMKL_00479 2.58e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EHHPBMKL_00480 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHHPBMKL_00481 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EHHPBMKL_00482 1.59e-286 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHHPBMKL_00483 8.61e-231 ydbI - - S - - - AI-2E family transporter
EHHPBMKL_00484 3.37e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_00485 3.47e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHHPBMKL_00486 5.4e-69 ydbL - - - - - - -
EHHPBMKL_00487 2.15e-261 ydbM - - I - - - acyl-CoA dehydrogenase
EHHPBMKL_00488 1.13e-15 - - - S - - - Fur-regulated basic protein B
EHHPBMKL_00489 9.35e-14 - - - S - - - Fur-regulated basic protein A
EHHPBMKL_00490 6.66e-159 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHHPBMKL_00491 2.25e-74 ydbP - - CO - - - Thioredoxin
EHHPBMKL_00492 2.52e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EHHPBMKL_00493 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EHHPBMKL_00494 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EHHPBMKL_00495 1.96e-108 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
EHHPBMKL_00496 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
EHHPBMKL_00497 2.96e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
EHHPBMKL_00498 1.09e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EHHPBMKL_00499 1.29e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
EHHPBMKL_00500 3.83e-277 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHHPBMKL_00501 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EHHPBMKL_00502 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EHHPBMKL_00503 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
EHHPBMKL_00504 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
EHHPBMKL_00505 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EHHPBMKL_00506 1.25e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
EHHPBMKL_00507 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
EHHPBMKL_00508 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EHHPBMKL_00509 1.61e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHPBMKL_00510 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
EHHPBMKL_00511 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
EHHPBMKL_00512 1.78e-21 - - - - - - - -
EHHPBMKL_00513 2.88e-74 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EHHPBMKL_00522 9.77e-150 - - - S - - - ATPase (AAA superfamily
EHHPBMKL_00524 3.81e-56 - - - - - - - -
EHHPBMKL_00525 3.49e-175 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EHHPBMKL_00527 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
EHHPBMKL_00528 1.04e-65 ohrR - - K - - - Transcriptional regulator
EHHPBMKL_00529 1.41e-93 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
EHHPBMKL_00530 2.13e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
EHHPBMKL_00531 1.59e-85 - - - S - - - YjbR
EHHPBMKL_00532 4.07e-97 ywnA - - K - - - Transcriptional regulator
EHHPBMKL_00533 2.22e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
EHHPBMKL_00534 1.97e-241 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EHHPBMKL_00535 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
EHHPBMKL_00536 8.42e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
EHHPBMKL_00537 1.53e-52 yrkD - - S - - - protein conserved in bacteria
EHHPBMKL_00538 9.32e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
EHHPBMKL_00539 1.42e-76 - - - P - - - Rhodanese Homology Domain
EHHPBMKL_00540 3.64e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
EHHPBMKL_00541 1.6e-251 yrkH - - P - - - Rhodanese Homology Domain
EHHPBMKL_00542 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
EHHPBMKL_00543 1.25e-166 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
EHHPBMKL_00544 8.33e-156 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EHHPBMKL_00545 1.48e-133 - - - S - - - Protein of unknown function (DUF2812)
EHHPBMKL_00546 9.96e-69 - - - K - - - Transcriptional regulator PadR-like family
EHHPBMKL_00547 1.45e-233 - - - S - - - Patatin-like phospholipase
EHHPBMKL_00548 6.08e-102 - - - S - - - DinB superfamily
EHHPBMKL_00549 4.11e-82 - - - G - - - Cupin domain
EHHPBMKL_00552 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
EHHPBMKL_00553 5.11e-214 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
EHHPBMKL_00554 9.68e-251 trkA - - P ko:K07222 - ko00000 Oxidoreductase
EHHPBMKL_00556 1.63e-131 yrkC - - G - - - Cupin domain
EHHPBMKL_00557 1.88e-98 ykkA - - S - - - Protein of unknown function (DUF664)
EHHPBMKL_00558 2.58e-37 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
EHHPBMKL_00559 3.29e-36 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
EHHPBMKL_00561 2.9e-254 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
EHHPBMKL_00562 1.19e-68 ydeH - - - - - - -
EHHPBMKL_00563 2.07e-212 - - - S - - - Sodium Bile acid symporter family
EHHPBMKL_00564 9.05e-258 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
EHHPBMKL_00565 4.93e-85 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
EHHPBMKL_00566 5.68e-281 nhaC_1 - - C - - - antiporter
EHHPBMKL_00567 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
EHHPBMKL_00568 3.59e-147 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_00570 3.57e-249 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
EHHPBMKL_00571 1.2e-132 ydeS - - K - - - Transcriptional regulator
EHHPBMKL_00572 2.5e-200 ydeK - - EG - - - -transporter
EHHPBMKL_00573 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHHPBMKL_00574 5.09e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
EHHPBMKL_00575 1.19e-33 yraE - - - ko:K06440 - ko00000 -
EHHPBMKL_00576 3.04e-282 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EHHPBMKL_00577 3.35e-84 yraF - - M - - - Spore coat protein
EHHPBMKL_00578 1.71e-49 yraG - - - ko:K06440 - ko00000 -
EHHPBMKL_00579 1.91e-272 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_00580 3.28e-141 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHPBMKL_00581 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
EHHPBMKL_00582 3.41e-171 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
EHHPBMKL_00583 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
EHHPBMKL_00584 7.5e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
EHHPBMKL_00585 4.59e-189 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHHPBMKL_00586 1.08e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
EHHPBMKL_00587 1.59e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EHHPBMKL_00588 3.76e-286 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHHPBMKL_00589 7.49e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
EHHPBMKL_00590 3.66e-157 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
EHHPBMKL_00591 5.09e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
EHHPBMKL_00592 6.89e-192 bltR - - K - - - helix_turn_helix, mercury resistance
EHHPBMKL_00593 2.1e-190 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EHHPBMKL_00594 1.35e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EHHPBMKL_00595 1.34e-187 - - - Q - - - ubiE/COQ5 methyltransferase family
EHHPBMKL_00596 9.74e-209 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
EHHPBMKL_00597 2.67e-153 ydhC - - K - - - FCD
EHHPBMKL_00598 1.94e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EHHPBMKL_00601 0.0 pbpE - - V - - - Beta-lactamase
EHHPBMKL_00603 2.49e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
EHHPBMKL_00604 1.29e-246 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
EHHPBMKL_00605 7.17e-172 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
EHHPBMKL_00606 1.55e-152 - - - K ko:K05799 - ko00000,ko03000 FCD
EHHPBMKL_00607 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
EHHPBMKL_00608 1.73e-64 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
EHHPBMKL_00609 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EHHPBMKL_00610 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
EHHPBMKL_00611 0.0 ybeC - - E - - - amino acid
EHHPBMKL_00612 1.04e-212 ydhU - - P ko:K07217 - ko00000 Catalase
EHHPBMKL_00613 1.7e-111 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
EHHPBMKL_00614 1.64e-236 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
EHHPBMKL_00615 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHHPBMKL_00618 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHHPBMKL_00621 4e-233 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHHPBMKL_00622 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
EHHPBMKL_00623 1.02e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
EHHPBMKL_00624 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EHHPBMKL_00625 6.49e-245 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHHPBMKL_00626 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
EHHPBMKL_00627 2.84e-115 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EHHPBMKL_00628 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EHHPBMKL_00629 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EHHPBMKL_00630 1.92e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHHPBMKL_00631 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
EHHPBMKL_00632 2.27e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
EHHPBMKL_00633 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHHPBMKL_00634 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EHHPBMKL_00635 0.0 yvfT - - T - - - helix_turn_helix, Lux Regulon
EHHPBMKL_00636 2.24e-127 - - - S - - - Putative sensor
EHHPBMKL_00637 0.0 pbpX - - V - - - Beta-lactamase
EHHPBMKL_00638 2.54e-98 yfiJ - - T - - - helix_turn_helix, Lux Regulon
EHHPBMKL_00639 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
EHHPBMKL_00640 1.69e-255 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
EHHPBMKL_00641 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
EHHPBMKL_00642 5.78e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
EHHPBMKL_00643 3.61e-41 yjdJ - - S - - - Domain of unknown function (DUF4306)
EHHPBMKL_00644 9.58e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
EHHPBMKL_00645 3.49e-226 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHHPBMKL_00646 4.16e-160 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
EHHPBMKL_00647 3.22e-223 ydjI - - S - - - virion core protein (lumpy skin disease virus)
EHHPBMKL_00648 0.0 oatA - - I - - - Acyltransferase family
EHHPBMKL_00649 9.73e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
EHHPBMKL_00650 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHHPBMKL_00651 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
EHHPBMKL_00652 1.6e-82 ydjM - - M - - - Lytic transglycolase
EHHPBMKL_00653 7.08e-195 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
EHHPBMKL_00655 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
EHHPBMKL_00656 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
EHHPBMKL_00657 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EHHPBMKL_00658 3.25e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
EHHPBMKL_00659 3.13e-274 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EHHPBMKL_00660 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
EHHPBMKL_00661 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EHHPBMKL_00662 5.95e-102 - - - - - - - -
EHHPBMKL_00663 1.9e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHHPBMKL_00664 0.0 - - - S - - - Domain of unknown function (DUF4179)
EHHPBMKL_00665 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EHHPBMKL_00666 2.16e-168 yebC - - M - - - Membrane
EHHPBMKL_00668 2.66e-120 yebE - - S - - - UPF0316 protein
EHHPBMKL_00669 2.21e-38 yebG - - S - - - NETI protein
EHHPBMKL_00670 3.78e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHHPBMKL_00671 4.56e-287 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHHPBMKL_00672 2.59e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHHPBMKL_00673 2.79e-165 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EHHPBMKL_00674 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHHPBMKL_00675 1.34e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHHPBMKL_00676 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHHPBMKL_00677 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHHPBMKL_00678 1.46e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EHHPBMKL_00679 9.96e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHHPBMKL_00680 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EHHPBMKL_00681 8.44e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EHHPBMKL_00682 1.03e-34 - - - S - - - Protein of unknown function (DUF2892)
EHHPBMKL_00683 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
EHHPBMKL_00684 4.95e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
EHHPBMKL_00685 2.03e-67 yerC - - S - - - protein conserved in bacteria
EHHPBMKL_00686 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
EHHPBMKL_00687 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EHHPBMKL_00688 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EHHPBMKL_00689 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHHPBMKL_00690 5.54e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
EHHPBMKL_00691 2.19e-249 yerI - - S - - - homoserine kinase type II (protein kinase fold)
EHHPBMKL_00692 1.44e-158 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EHHPBMKL_00693 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHHPBMKL_00694 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHHPBMKL_00695 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EHHPBMKL_00696 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHHPBMKL_00697 3.16e-197 yerO - - K - - - Transcriptional regulator
EHHPBMKL_00698 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHHPBMKL_00699 7.33e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EHHPBMKL_00700 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHHPBMKL_00701 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
EHHPBMKL_00702 9.62e-203 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EHHPBMKL_00703 6.78e-176 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
EHHPBMKL_00704 2.31e-80 - - - S - - - Protein of unknown function, DUF600
EHHPBMKL_00705 8.27e-67 - - - S - - - Protein of unknown function, DUF600
EHHPBMKL_00706 2.57e-60 - - - S - - - Protein of unknown function, DUF600
EHHPBMKL_00707 7.72e-68 - - - S - - - Protein of unknown function, DUF600
EHHPBMKL_00708 2.38e-101 - - - S - - - Protein of unknown function, DUF600
EHHPBMKL_00709 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
EHHPBMKL_00710 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
EHHPBMKL_00712 2.21e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
EHHPBMKL_00713 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
EHHPBMKL_00714 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
EHHPBMKL_00715 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
EHHPBMKL_00716 1.39e-123 yesJ - - K - - - Acetyltransferase (GNAT) family
EHHPBMKL_00717 5.92e-05 - - - - - - - -
EHHPBMKL_00718 8.99e-157 yetF - - S - - - membrane
EHHPBMKL_00719 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
EHHPBMKL_00720 3.78e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHPBMKL_00721 6.28e-197 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHHPBMKL_00722 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
EHHPBMKL_00723 1.82e-73 - - - H - - - riboflavin kinase activity
EHHPBMKL_00724 1.8e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
EHHPBMKL_00725 3.45e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHHPBMKL_00726 2.19e-267 yetM - - CH - - - FAD binding domain
EHHPBMKL_00727 2.28e-250 yetN - - S - - - Protein of unknown function (DUF3900)
EHHPBMKL_00728 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EHHPBMKL_00730 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EHHPBMKL_00731 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
EHHPBMKL_00732 3.93e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
EHHPBMKL_00733 1.9e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
EHHPBMKL_00734 7.24e-285 yfnE - - S - - - Glycosyltransferase like family 2
EHHPBMKL_00735 1.99e-238 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
EHHPBMKL_00736 1.56e-277 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_00737 8.39e-313 yfnA - - E ko:K03294 - ko00000 amino acid
EHHPBMKL_00738 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHHPBMKL_00739 2.85e-169 yfmS - - NT - - - chemotaxis protein
EHHPBMKL_00740 1.72e-214 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EHHPBMKL_00741 1.2e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHPBMKL_00742 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHHPBMKL_00743 2.05e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
EHHPBMKL_00744 5.93e-263 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
EHHPBMKL_00745 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHHPBMKL_00746 1.78e-264 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
EHHPBMKL_00747 9.42e-83 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
EHHPBMKL_00748 1.84e-236 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
EHHPBMKL_00749 7.35e-32 - - - S - - - Protein of unknown function (DUF3212)
EHHPBMKL_00750 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
EHHPBMKL_00751 3.93e-309 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EHHPBMKL_00752 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EHHPBMKL_00758 7.54e-07 - - - S - - - domain, Protein
EHHPBMKL_00760 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHHPBMKL_00761 1.38e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EHHPBMKL_00762 5.87e-228 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
EHHPBMKL_00763 1.65e-286 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EHHPBMKL_00764 1.4e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHHPBMKL_00765 1.74e-278 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EHHPBMKL_00766 4.77e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EHHPBMKL_00767 2.82e-155 yflK - - S - - - protein conserved in bacteria
EHHPBMKL_00768 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
EHHPBMKL_00769 1.98e-26 yflI - - - - - - -
EHHPBMKL_00770 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
EHHPBMKL_00771 9.02e-176 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EHHPBMKL_00772 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EHHPBMKL_00773 2.02e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
EHHPBMKL_00774 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EHHPBMKL_00775 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
EHHPBMKL_00776 1.18e-103 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHHPBMKL_00777 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
EHHPBMKL_00778 5.99e-50 ydgB - - S - - - Spore germination protein gerPA/gerPF
EHHPBMKL_00779 1.57e-313 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_00780 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHHPBMKL_00781 1.18e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
EHHPBMKL_00782 2.93e-158 frp - - C - - - nitroreductase
EHHPBMKL_00783 6e-167 yibF - - S - - - YibE/F-like protein
EHHPBMKL_00784 1.02e-246 yibE - - S - - - YibE/F-like protein
EHHPBMKL_00785 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
EHHPBMKL_00786 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EHHPBMKL_00787 6.43e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EHHPBMKL_00788 5.86e-208 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHHPBMKL_00789 3.38e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EHHPBMKL_00790 6.98e-252 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_00791 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
EHHPBMKL_00792 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHHPBMKL_00793 3.7e-70 yfkI - - S - - - gas vesicle protein
EHHPBMKL_00794 1.95e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EHHPBMKL_00795 6.71e-12 - - - - - - - -
EHHPBMKL_00796 4.6e-265 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_00797 1.4e-237 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
EHHPBMKL_00798 1.62e-185 yfkD - - S - - - YfkD-like protein
EHHPBMKL_00799 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
EHHPBMKL_00800 2.92e-282 yfkA - - S - - - YfkB-like domain
EHHPBMKL_00801 7.99e-37 yfjT - - - - - - -
EHHPBMKL_00802 3.59e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
EHHPBMKL_00803 4.82e-184 - - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHHPBMKL_00804 1.12e-103 - - - S ko:K19310 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacitracin ABC transporter permease
EHHPBMKL_00805 8.75e-92 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Bacitracin ABC transporter permease
EHHPBMKL_00806 4.57e-138 - - - K - - - Two component transcriptional regulator, winged helix family
EHHPBMKL_00807 2.8e-139 - - - T - - - His Kinase A (phosphoacceptor) domain
EHHPBMKL_00808 1.09e-190 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EHHPBMKL_00810 3.71e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
EHHPBMKL_00811 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHHPBMKL_00812 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHHPBMKL_00813 1.64e-62 - - - S - - - YfzA-like protein
EHHPBMKL_00814 3.47e-244 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHHPBMKL_00815 6.01e-115 yfjM - - S - - - Psort location Cytoplasmic, score
EHHPBMKL_00816 6.48e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHHPBMKL_00817 1.52e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHHPBMKL_00818 5.38e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHHPBMKL_00819 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHHPBMKL_00820 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
EHHPBMKL_00821 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
EHHPBMKL_00822 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EHHPBMKL_00823 9.01e-178 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
EHHPBMKL_00824 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_00825 3.72e-228 yobO - - M - - - COG5434 Endopolygalacturonase
EHHPBMKL_00826 1.89e-279 yobO - - M - - - COG5434 Endopolygalacturonase
EHHPBMKL_00827 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHHPBMKL_00828 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHHPBMKL_00829 5.54e-82 yfiD3 - - S - - - DoxX
EHHPBMKL_00830 4.72e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
EHHPBMKL_00831 7.58e-217 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EHHPBMKL_00832 5.62e-126 padR - - K - - - transcriptional
EHHPBMKL_00833 1.79e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
EHHPBMKL_00834 7.69e-236 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EHHPBMKL_00835 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EHHPBMKL_00836 2.36e-60 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
EHHPBMKL_00837 1.14e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
EHHPBMKL_00838 0.0 yfiU - - EGP - - - the major facilitator superfamily
EHHPBMKL_00839 7.97e-108 yfiV - - K - - - transcriptional
EHHPBMKL_00840 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EHHPBMKL_00841 7.26e-209 yfhB - - S - - - PhzF family
EHHPBMKL_00842 1.94e-136 yfhC - - C - - - nitroreductase
EHHPBMKL_00843 3.61e-34 yfhD - - S - - - YfhD-like protein
EHHPBMKL_00845 3.34e-212 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
EHHPBMKL_00846 3.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
EHHPBMKL_00847 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
EHHPBMKL_00848 2.86e-268 yfhI - - EGP - - - -transporter
EHHPBMKL_00850 3.34e-214 mpr - - M - - - Belongs to the peptidase S1B family
EHHPBMKL_00851 2.57e-59 yfhJ - - S - - - WVELL protein
EHHPBMKL_00852 3.85e-120 yfhK - - T - - - Bacterial SH3 domain homologues
EHHPBMKL_00853 2.99e-57 yfhL - - S - - - SdpI/YhfL protein family
EHHPBMKL_00854 6.8e-219 - - - S - - - Alpha/beta hydrolase family
EHHPBMKL_00855 1.57e-235 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHPBMKL_00856 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EHHPBMKL_00857 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
EHHPBMKL_00858 9.18e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
EHHPBMKL_00859 2.54e-50 yfhS - - - - - - -
EHHPBMKL_00860 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHPBMKL_00861 7.33e-07 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
EHHPBMKL_00862 1.4e-49 ygaB - - S - - - YgaB-like protein
EHHPBMKL_00863 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
EHHPBMKL_00864 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
EHHPBMKL_00865 5.27e-239 ygaE - - S - - - Membrane
EHHPBMKL_00866 2.79e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EHHPBMKL_00867 3.28e-110 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
EHHPBMKL_00868 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EHHPBMKL_00869 4.67e-75 ygzB - - S - - - UPF0295 protein
EHHPBMKL_00870 1.12e-212 ygxA - - S - - - Nucleotidyltransferase-like
EHHPBMKL_00871 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHHPBMKL_00888 4.79e-259 - - - C - - - Na+/H+ antiporter family
EHHPBMKL_00889 1.57e-172 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
EHHPBMKL_00890 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHHPBMKL_00891 0.0 ygaK - - C - - - Berberine and berberine like
EHHPBMKL_00893 9.91e-288 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
EHHPBMKL_00894 1.17e-178 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHHPBMKL_00895 8.8e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHPBMKL_00896 3.14e-169 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_00897 3.29e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_00898 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EHHPBMKL_00899 4.68e-234 - - - S ko:K07045 - ko00000 Amidohydrolase
EHHPBMKL_00900 1.5e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EHHPBMKL_00901 7.12e-229 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
EHHPBMKL_00902 8.27e-186 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EHHPBMKL_00903 1.17e-270 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
EHHPBMKL_00904 3.39e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHHPBMKL_00905 1.29e-106 ygaO - - - - - - -
EHHPBMKL_00906 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_00908 7.82e-147 yhzB - - S - - - B3/4 domain
EHHPBMKL_00909 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHHPBMKL_00910 2.08e-225 yhbB - - S - - - Putative amidase domain
EHHPBMKL_00911 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EHHPBMKL_00912 4.63e-139 yhbD - - K - - - Protein of unknown function (DUF4004)
EHHPBMKL_00913 3.99e-85 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EHHPBMKL_00914 2.02e-94 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EHHPBMKL_00915 1.23e-07 - - - - - - - -
EHHPBMKL_00916 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
EHHPBMKL_00917 5.45e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
EHHPBMKL_00918 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
EHHPBMKL_00919 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
EHHPBMKL_00920 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
EHHPBMKL_00921 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
EHHPBMKL_00922 1.41e-72 yhcC - - - - - - -
EHHPBMKL_00923 1.6e-89 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_00924 2.23e-209 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHHPBMKL_00925 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
EHHPBMKL_00926 5.86e-190 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EHHPBMKL_00927 1.01e-234 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
EHHPBMKL_00928 4.31e-292 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHHPBMKL_00929 1.74e-72 yhcM - - - - - - -
EHHPBMKL_00930 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHHPBMKL_00931 1.85e-204 yhcP - - - - - - -
EHHPBMKL_00932 4.45e-151 yhcQ - - M - - - Spore coat protein
EHHPBMKL_00933 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHHPBMKL_00934 1.3e-136 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
EHHPBMKL_00935 2.27e-216 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EHHPBMKL_00936 7.37e-90 yhcU - - S - - - Family of unknown function (DUF5365)
EHHPBMKL_00937 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
EHHPBMKL_00938 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
EHHPBMKL_00939 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EHHPBMKL_00940 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHHPBMKL_00941 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EHHPBMKL_00942 2.83e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EHHPBMKL_00943 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHHPBMKL_00944 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHHPBMKL_00945 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
EHHPBMKL_00946 8.75e-262 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_00947 1.56e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHPBMKL_00948 9.77e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
EHHPBMKL_00949 1.16e-51 yhdB - - S - - - YhdB-like protein
EHHPBMKL_00950 2.94e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
EHHPBMKL_00951 1.04e-297 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EHHPBMKL_00952 3.79e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
EHHPBMKL_00953 0.0 ygxB - - M - - - Conserved TM helix
EHHPBMKL_00954 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
EHHPBMKL_00955 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EHHPBMKL_00956 2.8e-171 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EHHPBMKL_00957 8.17e-209 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_00958 6.39e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EHHPBMKL_00959 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHPBMKL_00960 1.78e-316 yhdG - - E ko:K03294 - ko00000 amino acid
EHHPBMKL_00961 8.02e-265 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EHHPBMKL_00962 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
EHHPBMKL_00963 6.88e-257 yhdL - - S - - - Sigma factor regulator N-terminal
EHHPBMKL_00964 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHHPBMKL_00965 9.21e-142 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EHHPBMKL_00966 2.28e-306 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHHPBMKL_00967 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
EHHPBMKL_00968 4.05e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EHHPBMKL_00969 9.1e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHHPBMKL_00970 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
EHHPBMKL_00971 2.9e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHHPBMKL_00972 4.97e-79 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHHPBMKL_00973 1.49e-164 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EHHPBMKL_00974 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
EHHPBMKL_00975 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
EHHPBMKL_00976 7.18e-181 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EHHPBMKL_00977 4.01e-200 nodB1 - - G - - - deacetylase
EHHPBMKL_00978 3.99e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EHHPBMKL_00979 1.43e-113 pksA - - K - - - Transcriptional regulator
EHHPBMKL_00980 3.12e-123 ymcC - - S - - - Membrane
EHHPBMKL_00981 2.49e-110 - - - T - - - universal stress protein
EHHPBMKL_00983 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHHPBMKL_00984 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EHHPBMKL_00985 7.8e-142 yheG - - GM - - - NAD(P)H-binding
EHHPBMKL_00987 3.3e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
EHHPBMKL_00988 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
EHHPBMKL_00989 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
EHHPBMKL_00990 1.54e-272 yheC - - HJ - - - YheC/D like ATP-grasp
EHHPBMKL_00991 7.84e-264 yheB - - S - - - Belongs to the UPF0754 family
EHHPBMKL_00992 2.32e-70 yheA - - S - - - Belongs to the UPF0342 family
EHHPBMKL_00993 1.74e-258 yhaZ - - L - - - DNA alkylation repair enzyme
EHHPBMKL_00994 2.95e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
EHHPBMKL_00995 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
EHHPBMKL_00996 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
EHHPBMKL_00997 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
EHHPBMKL_00998 3.62e-111 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EHHPBMKL_01000 1.18e-174 yhaR - - I - - - enoyl-CoA hydratase
EHHPBMKL_01001 5.99e-21 - - - S - - - YhzD-like protein
EHHPBMKL_01002 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_01003 4.82e-277 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
EHHPBMKL_01004 7.47e-300 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
EHHPBMKL_01005 0.0 yhaN - - L - - - AAA domain
EHHPBMKL_01006 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
EHHPBMKL_01007 4.95e-44 yhaL - - S - - - Sporulation protein YhaL
EHHPBMKL_01008 1.36e-183 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EHHPBMKL_01009 1.29e-123 yhaK - - S - - - Putative zincin peptidase
EHHPBMKL_01010 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
EHHPBMKL_01011 4.73e-146 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
EHHPBMKL_01012 4.74e-55 yhaH - - S - - - YtxH-like protein
EHHPBMKL_01013 2.55e-24 - - - - - - - -
EHHPBMKL_01014 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
EHHPBMKL_01015 5.91e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHHPBMKL_01016 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EHHPBMKL_01017 3.02e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
EHHPBMKL_01018 6.41e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EHHPBMKL_01019 1.75e-161 ecsC - - S - - - EcsC protein family
EHHPBMKL_01020 1.53e-286 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EHHPBMKL_01021 3.98e-311 yhfA - - C - - - membrane
EHHPBMKL_01022 3.1e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
EHHPBMKL_01023 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHHPBMKL_01024 8.58e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHHPBMKL_01025 4.49e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
EHHPBMKL_01026 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EHHPBMKL_01027 4.41e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_01028 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
EHHPBMKL_01029 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHHPBMKL_01031 2.11e-250 yhfE - - G - - - peptidase M42
EHHPBMKL_01032 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHHPBMKL_01034 4.01e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EHHPBMKL_01035 6.47e-242 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EHHPBMKL_01036 1.05e-141 yhfK - - GM - - - NmrA-like family
EHHPBMKL_01037 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EHHPBMKL_01038 7.96e-85 yhfM - - - - - - -
EHHPBMKL_01039 3.56e-298 yhfN - - O - - - Peptidase M48
EHHPBMKL_01040 1.57e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHHPBMKL_01041 7.33e-192 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EHHPBMKL_01042 6.03e-134 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
EHHPBMKL_01043 2.38e-251 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EHHPBMKL_01044 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EHHPBMKL_01045 7.56e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EHHPBMKL_01046 1.87e-275 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
EHHPBMKL_01047 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
EHHPBMKL_01048 3.88e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHPBMKL_01049 3.87e-42 yhzC - - S - - - IDEAL
EHHPBMKL_01050 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
EHHPBMKL_01051 2.09e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
EHHPBMKL_01052 4.93e-82 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
EHHPBMKL_01053 1.49e-161 yrpD - - S - - - Domain of unknown function, YrpD
EHHPBMKL_01054 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
EHHPBMKL_01055 2.64e-63 - - - S - - - Belongs to the UPF0145 family
EHHPBMKL_01056 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHHPBMKL_01057 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
EHHPBMKL_01058 4.12e-79 yhjD - - - - - - -
EHHPBMKL_01059 2.23e-142 yhjE - - S - - - SNARE associated Golgi protein
EHHPBMKL_01060 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHHPBMKL_01061 0.0 yhjG - - CH - - - FAD binding domain
EHHPBMKL_01062 4.89e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHHPBMKL_01063 9.85e-262 yhjN - - S ko:K07120 - ko00000 membrane
EHHPBMKL_01064 1.78e-266 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_01065 1.06e-139 - - - K - - - QacR-like protein, C-terminal region
EHHPBMKL_01066 3.6e-122 yhjR - - S - - - Rubrerythrin
EHHPBMKL_01067 5.11e-153 ydfS - - S - - - Protein of unknown function (DUF421)
EHHPBMKL_01068 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
EHHPBMKL_01069 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EHHPBMKL_01070 4.7e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EHHPBMKL_01071 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
EHHPBMKL_01072 6.24e-66 yisB - - V - - - COG1403 Restriction endonuclease
EHHPBMKL_01073 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
EHHPBMKL_01074 1.09e-82 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
EHHPBMKL_01075 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
EHHPBMKL_01076 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
EHHPBMKL_01077 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
EHHPBMKL_01078 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
EHHPBMKL_01079 1.59e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
EHHPBMKL_01080 1.54e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EHHPBMKL_01081 2.22e-78 yisL - - S - - - UPF0344 protein
EHHPBMKL_01082 2.17e-123 yisN - - S - - - Protein of unknown function (DUF2777)
EHHPBMKL_01083 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EHHPBMKL_01084 1.81e-169 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
EHHPBMKL_01085 6.12e-312 yisQ - - V - - - Mate efflux family protein
EHHPBMKL_01086 4.72e-206 yisR - - K - - - Transcriptional regulator
EHHPBMKL_01087 4.31e-31 - 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
EHHPBMKL_01088 1.48e-114 yisT - - S - - - DinB family
EHHPBMKL_01089 1.71e-95 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
EHHPBMKL_01090 5.57e-238 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHHPBMKL_01091 1.6e-103 yisX - - S - - - Pentapeptide repeats (9 copies)
EHHPBMKL_01092 1.8e-104 - - - S - - - Acetyltransferase (GNAT) domain
EHHPBMKL_01093 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EHHPBMKL_01094 3.69e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
EHHPBMKL_01095 7.54e-205 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
EHHPBMKL_01096 8.51e-219 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
EHHPBMKL_01097 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
EHHPBMKL_01098 1.79e-307 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
EHHPBMKL_01100 5.5e-203 yitS - - S - - - protein conserved in bacteria
EHHPBMKL_01101 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHHPBMKL_01102 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
EHHPBMKL_01103 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
EHHPBMKL_01104 1.49e-11 - - - - - - - -
EHHPBMKL_01105 5.08e-197 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EHHPBMKL_01106 8.73e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EHHPBMKL_01107 1.33e-67 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
EHHPBMKL_01108 1.12e-103 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EHHPBMKL_01109 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
EHHPBMKL_01110 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
EHHPBMKL_01111 5.84e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHHPBMKL_01112 2.99e-289 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EHHPBMKL_01113 5.17e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
EHHPBMKL_01114 3.98e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
EHHPBMKL_01115 2.31e-257 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EHHPBMKL_01116 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
EHHPBMKL_01117 8.28e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHHPBMKL_01118 7.21e-39 yjzC - - S - - - YjzC-like protein
EHHPBMKL_01119 1.24e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
EHHPBMKL_01120 3.04e-176 yjaU - - I - - - carboxylic ester hydrolase activity
EHHPBMKL_01121 1.67e-134 yjaV - - - - - - -
EHHPBMKL_01122 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
EHHPBMKL_01123 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
EHHPBMKL_01124 2.72e-42 yjzB - - - - - - -
EHHPBMKL_01125 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHHPBMKL_01126 9.08e-299 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHHPBMKL_01127 7.48e-190 yjaZ - - O - - - Zn-dependent protease
EHHPBMKL_01128 8.37e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_01129 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_01130 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
EHHPBMKL_01131 5.76e-217 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHPBMKL_01132 1.67e-198 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHPBMKL_01133 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
EHHPBMKL_01134 4.85e-232 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
EHHPBMKL_01135 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHHPBMKL_01136 1.46e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHPBMKL_01137 6.93e-208 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHPBMKL_01138 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_01139 1.42e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_01140 3.5e-295 - - - S - - - Putative glycosyl hydrolase domain
EHHPBMKL_01141 2.55e-131 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHPBMKL_01142 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EHHPBMKL_01143 4.59e-140 yjbE - - P - - - Integral membrane protein TerC family
EHHPBMKL_01144 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EHHPBMKL_01145 9.45e-281 coiA - - S ko:K06198 - ko00000 Competence protein
EHHPBMKL_01146 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EHHPBMKL_01147 1.06e-25 - - - - - - - -
EHHPBMKL_01148 1.22e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EHHPBMKL_01149 2.03e-92 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
EHHPBMKL_01150 3.12e-152 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EHHPBMKL_01151 1.72e-128 yjbK - - S - - - protein conserved in bacteria
EHHPBMKL_01152 4.78e-79 yjbL - - S - - - Belongs to the UPF0738 family
EHHPBMKL_01153 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
EHHPBMKL_01154 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHHPBMKL_01155 2.35e-211 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EHHPBMKL_01156 3.05e-183 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EHHPBMKL_01157 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EHHPBMKL_01158 5.26e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHHPBMKL_01159 8.09e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
EHHPBMKL_01160 4.57e-268 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
EHHPBMKL_01161 5.5e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
EHHPBMKL_01162 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EHHPBMKL_01163 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EHHPBMKL_01164 4.3e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EHHPBMKL_01165 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EHHPBMKL_01166 7.96e-124 yjbX - - S - - - Spore coat protein
EHHPBMKL_01167 2.1e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
EHHPBMKL_01168 2.48e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
EHHPBMKL_01169 1.51e-99 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
EHHPBMKL_01170 4.1e-43 cotW - - - ko:K06341 - ko00000 -
EHHPBMKL_01171 9.7e-71 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
EHHPBMKL_01172 8.37e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
EHHPBMKL_01175 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EHHPBMKL_01176 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
EHHPBMKL_01177 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHHPBMKL_01178 2.48e-48 - - - - - - - -
EHHPBMKL_01179 2.06e-181 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
EHHPBMKL_01180 4.59e-160 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
EHHPBMKL_01181 3.53e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EHHPBMKL_01182 4.32e-48 - - - K - - - SpoVT / AbrB like domain
EHHPBMKL_01183 2.48e-96 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHPBMKL_01184 6.97e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
EHHPBMKL_01185 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
EHHPBMKL_01186 3.93e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHHPBMKL_01187 1.37e-271 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHHPBMKL_01189 1.14e-26 - - - - - - - -
EHHPBMKL_01190 1.42e-29 - - - - - - - -
EHHPBMKL_01191 9.34e-51 - - - - - - - -
EHHPBMKL_01193 4.74e-247 - - - M - - - nucleic acid phosphodiester bond hydrolysis
EHHPBMKL_01197 3.27e-78 - - - E - - - Glyoxalase-like domain
EHHPBMKL_01198 1.64e-210 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
EHHPBMKL_01199 3.12e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
EHHPBMKL_01200 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
EHHPBMKL_01201 1.06e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHHPBMKL_01202 1.34e-281 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
EHHPBMKL_01203 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EHHPBMKL_01204 2.09e-242 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EHHPBMKL_01205 4.28e-274 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHHPBMKL_01206 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHHPBMKL_01207 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_01208 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHHPBMKL_01209 1.62e-176 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHHPBMKL_01210 1.62e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
EHHPBMKL_01211 1.69e-46 - - - - - - - -
EHHPBMKL_01212 1.19e-68 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHHPBMKL_01213 2.89e-135 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EHHPBMKL_01215 1.91e-31 yjfB - - S - - - Putative motility protein
EHHPBMKL_01216 1.48e-90 yjgA - - T - - - Protein of unknown function (DUF2809)
EHHPBMKL_01217 3.92e-129 yjgB - - S - - - Domain of unknown function (DUF4309)
EHHPBMKL_01218 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
EHHPBMKL_01219 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
EHHPBMKL_01220 3.25e-291 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHHPBMKL_01221 1.64e-283 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EHHPBMKL_01222 1.73e-40 - - - - - - - -
EHHPBMKL_01223 4.13e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EHHPBMKL_01224 3.6e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
EHHPBMKL_01225 3.08e-166 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_01226 2.38e-226 yjlA - - EG - - - Putative multidrug resistance efflux transporter
EHHPBMKL_01227 4.96e-118 yjlB - - S - - - Cupin domain
EHHPBMKL_01228 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
EHHPBMKL_01229 1.76e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EHHPBMKL_01230 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
EHHPBMKL_01231 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
EHHPBMKL_01232 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
EHHPBMKL_01233 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
EHHPBMKL_01234 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EHHPBMKL_01235 1.83e-112 - - - T - - - Transcriptional regulatory protein, C terminal
EHHPBMKL_01236 4.91e-167 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EHHPBMKL_01237 1.11e-132 - - - V ko:K01990,ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_01238 7.74e-86 - - - S - - - ABC-2 family transporter protein
EHHPBMKL_01240 4.67e-50 - 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_01241 1.26e-75 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHPBMKL_01243 0.0 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
EHHPBMKL_01244 2.77e-276 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Peptidase C39 family
EHHPBMKL_01247 3.25e-243 lcnDR2 - - V - - - Domain of unknown function (DUF4135)
EHHPBMKL_01248 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
EHHPBMKL_01249 8.38e-103 yjoA - - S - - - DinB family
EHHPBMKL_01250 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EHHPBMKL_01252 1.94e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EHHPBMKL_01253 9.51e-81 yjqA - - S - - - Bacterial PH domain
EHHPBMKL_01254 2.63e-142 yjqB - - S - - - phage-related replication protein
EHHPBMKL_01255 6.51e-145 xkdA - - E - - - IrrE N-terminal-like domain
EHHPBMKL_01256 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
EHHPBMKL_01258 2.94e-194 xkdC - - L - - - Bacterial dnaA protein
EHHPBMKL_01262 3.05e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EHHPBMKL_01263 1.24e-142 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
EHHPBMKL_01264 1.36e-262 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
EHHPBMKL_01265 5.17e-304 xkdE3 - - S - - - portal protein
EHHPBMKL_01266 8.8e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
EHHPBMKL_01267 8.3e-203 xkdG - - S - - - Phage capsid family
EHHPBMKL_01268 3.6e-60 yqbG - - S - - - Protein of unknown function (DUF3199)
EHHPBMKL_01269 1.42e-56 - - - S - - - Domain of unknown function (DUF3599)
EHHPBMKL_01270 8.03e-76 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
EHHPBMKL_01271 1.05e-74 xkdJ - - - - - - -
EHHPBMKL_01272 1.45e-20 - - - - - - - -
EHHPBMKL_01273 2.31e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
EHHPBMKL_01274 8.21e-97 xkdM - - S - - - Phage tail tube protein
EHHPBMKL_01275 2.09e-95 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EHHPBMKL_01276 4.33e-27 - - - - - - - -
EHHPBMKL_01277 5.5e-272 xkdO - - L - - - Transglycosylase SLT domain
EHHPBMKL_01278 6.56e-145 xkdP - - S - - - Lysin motif
EHHPBMKL_01279 2.66e-206 xkdQ - - G - - - NLP P60 protein
EHHPBMKL_01280 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
EHHPBMKL_01281 4.74e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
EHHPBMKL_01282 4.38e-212 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EHHPBMKL_01283 4.1e-112 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EHHPBMKL_01284 8.92e-38 - - - - - - - -
EHHPBMKL_01285 4.87e-109 - - - - - - - -
EHHPBMKL_01287 1.32e-39 xkdX - - - - - - -
EHHPBMKL_01288 3.67e-177 xepA - - - - - - -
EHHPBMKL_01289 3.87e-51 xhlA - - S - - - Haemolysin XhlA
EHHPBMKL_01290 4.7e-52 xhlB - - S - - - SPP1 phage holin
EHHPBMKL_01291 2.02e-214 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EHHPBMKL_01292 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
EHHPBMKL_01293 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
EHHPBMKL_01294 1.22e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
EHHPBMKL_01295 1.2e-140 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
EHHPBMKL_01296 1.33e-311 steT - - E ko:K03294 - ko00000 amino acid
EHHPBMKL_01297 4.3e-228 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EHHPBMKL_01298 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHHPBMKL_01299 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHPBMKL_01301 1.07e-275 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHHPBMKL_01302 0.0 yubD - - P - - - Major Facilitator Superfamily
EHHPBMKL_01303 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
EHHPBMKL_01304 3.98e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHPBMKL_01305 1.89e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHPBMKL_01306 4.37e-241 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_01307 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHHPBMKL_01308 1.09e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
EHHPBMKL_01309 4.3e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EHHPBMKL_01310 2.55e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EHHPBMKL_01311 6.62e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_01312 3.43e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
EHHPBMKL_01313 3.44e-203 ykgA - - E - - - Amidinotransferase
EHHPBMKL_01314 3.06e-120 ykhA - - I - - - Acyl-CoA hydrolase
EHHPBMKL_01315 7.43e-130 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHHPBMKL_01316 2.37e-68 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
EHHPBMKL_01317 4.97e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
EHHPBMKL_01318 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EHHPBMKL_01319 1.77e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHHPBMKL_01320 7.94e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHHPBMKL_01321 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
EHHPBMKL_01322 9.88e-111 ohrR - - K - - - COG1846 Transcriptional regulators
EHHPBMKL_01323 3.2e-91 ohrB - - O - - - Organic hydroperoxide resistance protein
EHHPBMKL_01324 6.7e-82 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EHHPBMKL_01326 7.1e-275 - - - M - - - Glycosyl transferase family 2
EHHPBMKL_01327 1.78e-175 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
EHHPBMKL_01328 1.98e-133 - - - S - - - AAA ATPase domain
EHHPBMKL_01329 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHHPBMKL_01330 2.58e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHHPBMKL_01331 1.28e-189 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHHPBMKL_01332 2.18e-169 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EHHPBMKL_01333 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_01334 4.66e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EHHPBMKL_01335 1.27e-309 ydhD - - M - - - Glycosyl hydrolase
EHHPBMKL_01337 3.52e-309 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
EHHPBMKL_01338 1.23e-69 tnrA - - K - - - transcriptional
EHHPBMKL_01339 1.11e-23 - - - - - - - -
EHHPBMKL_01340 5.25e-37 ykoL - - - - - - -
EHHPBMKL_01341 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
EHHPBMKL_01342 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
EHHPBMKL_01343 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
EHHPBMKL_01344 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EHHPBMKL_01345 1.43e-131 ykoX - - S - - - membrane-associated protein
EHHPBMKL_01346 2.91e-173 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EHHPBMKL_01347 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHPBMKL_01348 3.6e-250 ykrI - - S - - - Anti-sigma factor N-terminus
EHHPBMKL_01349 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
EHHPBMKL_01350 1.62e-161 ykrK - - S - - - Domain of unknown function (DUF1836)
EHHPBMKL_01351 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EHHPBMKL_01352 1.62e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
EHHPBMKL_01353 3e-148 - - - S - - - Protein of unknown function (DUF421)
EHHPBMKL_01354 3.07e-32 ykzE - - - - - - -
EHHPBMKL_01355 3.74e-241 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
EHHPBMKL_01356 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_01357 1.31e-113 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHHPBMKL_01359 4.44e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EHHPBMKL_01360 2.44e-287 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EHHPBMKL_01361 1.57e-190 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EHHPBMKL_01362 1.04e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EHHPBMKL_01363 7.51e-287 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EHHPBMKL_01364 9.47e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EHHPBMKL_01365 2.61e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EHHPBMKL_01366 2.05e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EHHPBMKL_01368 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EHHPBMKL_01369 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
EHHPBMKL_01370 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EHHPBMKL_01371 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EHHPBMKL_01372 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EHHPBMKL_01373 1.73e-228 ykvI - - S - - - membrane
EHHPBMKL_01374 6.57e-254 - - - - - - - -
EHHPBMKL_01375 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHHPBMKL_01376 6.25e-103 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
EHHPBMKL_01377 1.76e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EHHPBMKL_01378 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHHPBMKL_01380 2.54e-77 ykvN - - K - - - Transcriptional regulator
EHHPBMKL_01381 2.47e-168 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EHHPBMKL_01382 3.91e-42 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHHPBMKL_01383 6e-59 ykvR - - S - - - Protein of unknown function (DUF3219)
EHHPBMKL_01384 5.43e-35 ykvS - - S - - - protein conserved in bacteria
EHHPBMKL_01385 7.17e-39 - - - - - - - -
EHHPBMKL_01386 8.42e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
EHHPBMKL_01387 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHPBMKL_01388 8.57e-114 stoA - - CO - - - thiol-disulfide
EHHPBMKL_01389 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EHHPBMKL_01390 4.71e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EHHPBMKL_01392 1.01e-224 ykvZ - - K - - - Transcriptional regulator
EHHPBMKL_01393 4.61e-198 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
EHHPBMKL_01394 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_01395 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
EHHPBMKL_01396 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHHPBMKL_01397 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_01398 3.53e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
EHHPBMKL_01399 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHHPBMKL_01400 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EHHPBMKL_01401 2.94e-168 ykwD - - J - - - protein with SCP PR1 domains
EHHPBMKL_01402 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EHHPBMKL_01403 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_01404 3.28e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EHHPBMKL_01405 6.38e-15 - - - - - - - -
EHHPBMKL_01406 3.2e-212 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
EHHPBMKL_01407 5.07e-108 ykyB - - S - - - YkyB-like protein
EHHPBMKL_01408 4.6e-308 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_01409 2.55e-116 ykuD - - S - - - protein conserved in bacteria
EHHPBMKL_01410 3.66e-197 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
EHHPBMKL_01411 1.5e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHPBMKL_01413 1.82e-295 ykuI - - T - - - Diguanylate phosphodiesterase
EHHPBMKL_01414 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
EHHPBMKL_01415 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
EHHPBMKL_01416 3.09e-35 ykzF - - S - - - Antirepressor AbbA
EHHPBMKL_01417 8.55e-99 ykuL - - S - - - CBS domain
EHHPBMKL_01418 1.32e-215 ccpC - - K - - - Transcriptional regulator
EHHPBMKL_01419 6.12e-115 ykuN - - C ko:K03839 - ko00000 Flavodoxin
EHHPBMKL_01420 1.95e-219 ykuO - - - - - - -
EHHPBMKL_01421 2.16e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
EHHPBMKL_01422 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EHHPBMKL_01423 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EHHPBMKL_01424 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
EHHPBMKL_01425 1.73e-178 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
EHHPBMKL_01426 1.92e-102 ykuV - - CO - - - thiol-disulfide
EHHPBMKL_01427 3.04e-126 rok - - K - - - Repressor of ComK
EHHPBMKL_01428 6.93e-216 yknT - - - ko:K06437 - ko00000 -
EHHPBMKL_01429 1.93e-139 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EHHPBMKL_01430 1.41e-240 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EHHPBMKL_01431 2.78e-309 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
EHHPBMKL_01432 3.21e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
EHHPBMKL_01433 7.17e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
EHHPBMKL_01434 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHHPBMKL_01435 7.69e-139 yknW - - S - - - Yip1 domain
EHHPBMKL_01436 1.64e-245 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHHPBMKL_01437 2.38e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_01438 2.98e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
EHHPBMKL_01439 9.28e-170 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_01440 5.54e-213 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
EHHPBMKL_01441 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EHHPBMKL_01442 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHHPBMKL_01443 3.68e-50 ykoA - - - - - - -
EHHPBMKL_01444 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHHPBMKL_01445 1.08e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHHPBMKL_01446 1.2e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
EHHPBMKL_01447 4.47e-18 - - - S - - - Uncharacterized protein YkpC
EHHPBMKL_01448 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
EHHPBMKL_01449 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
EHHPBMKL_01450 1.68e-312 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EHHPBMKL_01451 5.27e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
EHHPBMKL_01452 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EHHPBMKL_01453 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EHHPBMKL_01454 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHHPBMKL_01455 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
EHHPBMKL_01456 1.51e-187 ykrA - - S - - - hydrolases of the HAD superfamily
EHHPBMKL_01457 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EHHPBMKL_01458 7.91e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EHHPBMKL_01459 1.73e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
EHHPBMKL_01460 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHHPBMKL_01461 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_01462 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
EHHPBMKL_01463 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_01464 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_01465 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_01466 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_01467 0.0 - - - IQ - - - Phosphopantetheine attachment site
EHHPBMKL_01468 3.73e-264 - - - V - - - Beta-lactamase
EHHPBMKL_01469 6.68e-262 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHHPBMKL_01470 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHHPBMKL_01471 2.08e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHHPBMKL_01472 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHHPBMKL_01473 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
EHHPBMKL_01474 8.08e-192 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EHHPBMKL_01475 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
EHHPBMKL_01476 3.83e-56 yktA - - S - - - Belongs to the UPF0223 family
EHHPBMKL_01477 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
EHHPBMKL_01478 3.33e-33 ykzI - - - - - - -
EHHPBMKL_01479 7.8e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
EHHPBMKL_01480 1.07e-107 ykzC - - S - - - Acetyltransferase (GNAT) family
EHHPBMKL_01481 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EHHPBMKL_01483 2.83e-62 ylaE - - - - - - -
EHHPBMKL_01484 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
EHHPBMKL_01485 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EHHPBMKL_01486 2.44e-65 - - - S - - - YlaH-like protein
EHHPBMKL_01487 6.78e-46 ylaI - - S - - - protein conserved in bacteria
EHHPBMKL_01488 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHHPBMKL_01489 2.7e-313 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
EHHPBMKL_01490 1.75e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EHHPBMKL_01491 5.18e-221 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EHHPBMKL_01492 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
EHHPBMKL_01493 8.59e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EHHPBMKL_01494 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EHHPBMKL_01495 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EHHPBMKL_01496 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EHHPBMKL_01497 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EHHPBMKL_01498 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHHPBMKL_01499 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EHHPBMKL_01500 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EHHPBMKL_01501 8.46e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
EHHPBMKL_01502 4.12e-79 ylbA - - S - - - YugN-like family
EHHPBMKL_01503 9.59e-96 ylbB - - T - - - COG0517 FOG CBS domain
EHHPBMKL_01504 3.97e-255 ylbC - - S - - - protein with SCP PR1 domains
EHHPBMKL_01505 1.03e-87 ylbD - - S - - - Putative coat protein
EHHPBMKL_01506 1.73e-48 ylbE - - S - - - YlbE-like protein
EHHPBMKL_01507 2.74e-96 ylbF - - S - - - Belongs to the UPF0342 family
EHHPBMKL_01508 3.94e-57 ylbG - - S - - - UPF0298 protein
EHHPBMKL_01509 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
EHHPBMKL_01510 8.3e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHHPBMKL_01511 9.73e-276 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
EHHPBMKL_01512 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EHHPBMKL_01513 8.8e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EHHPBMKL_01514 5.23e-295 ylbM - - S - - - Belongs to the UPF0348 family
EHHPBMKL_01515 3.3e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
EHHPBMKL_01516 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EHHPBMKL_01517 1.27e-110 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EHHPBMKL_01518 1.14e-116 ylbP - - K - - - n-acetyltransferase
EHHPBMKL_01519 2.85e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHHPBMKL_01520 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EHHPBMKL_01521 1.03e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EHHPBMKL_01522 8.23e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EHHPBMKL_01523 2.4e-68 ftsL - - D - - - Essential cell division protein
EHHPBMKL_01524 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EHHPBMKL_01525 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
EHHPBMKL_01526 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHHPBMKL_01527 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHHPBMKL_01528 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHHPBMKL_01529 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EHHPBMKL_01530 3.29e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHHPBMKL_01531 7.87e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
EHHPBMKL_01532 2.67e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EHHPBMKL_01533 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EHHPBMKL_01534 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHHPBMKL_01535 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
EHHPBMKL_01536 8.23e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EHHPBMKL_01537 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHPBMKL_01538 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHPBMKL_01539 8.04e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EHHPBMKL_01540 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
EHHPBMKL_01541 7.13e-52 ylmC - - S - - - sporulation protein
EHHPBMKL_01542 9.55e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
EHHPBMKL_01543 3.68e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHHPBMKL_01544 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EHHPBMKL_01545 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
EHHPBMKL_01546 6.12e-182 ylmH - - S - - - conserved protein, contains S4-like domain
EHHPBMKL_01547 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
EHHPBMKL_01548 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHHPBMKL_01549 4.75e-80 ylyA - - T - - - COG1734 DnaK suppressor protein
EHHPBMKL_01550 1.02e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHHPBMKL_01551 5.35e-216 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EHHPBMKL_01552 8.98e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EHHPBMKL_01553 2.81e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
EHHPBMKL_01554 1.47e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EHHPBMKL_01555 1.55e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EHHPBMKL_01556 8.86e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EHHPBMKL_01557 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
EHHPBMKL_01558 1.18e-179 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EHHPBMKL_01559 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EHHPBMKL_01560 3.66e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EHHPBMKL_01561 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHHPBMKL_01563 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EHHPBMKL_01564 1.21e-228 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
EHHPBMKL_01565 1.77e-283 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EHHPBMKL_01566 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EHHPBMKL_01567 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EHHPBMKL_01568 4.15e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
EHHPBMKL_01569 6.27e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
EHHPBMKL_01570 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
EHHPBMKL_01571 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
EHHPBMKL_01572 2.14e-198 yloC - - S - - - stress-induced protein
EHHPBMKL_01573 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
EHHPBMKL_01574 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EHHPBMKL_01575 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EHHPBMKL_01576 2.09e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHHPBMKL_01577 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHHPBMKL_01578 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EHHPBMKL_01579 2.64e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHHPBMKL_01580 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHHPBMKL_01581 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EHHPBMKL_01582 2.03e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EHHPBMKL_01583 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EHHPBMKL_01584 6.22e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EHHPBMKL_01585 3.42e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EHHPBMKL_01586 4.34e-152 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EHHPBMKL_01587 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EHHPBMKL_01588 3.65e-78 yloU - - S - - - protein conserved in bacteria
EHHPBMKL_01589 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
EHHPBMKL_01590 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EHHPBMKL_01591 9.75e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EHHPBMKL_01592 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHHPBMKL_01593 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EHHPBMKL_01594 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EHHPBMKL_01595 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHHPBMKL_01596 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EHHPBMKL_01597 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHHPBMKL_01598 1.23e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EHHPBMKL_01599 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EHHPBMKL_01600 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EHHPBMKL_01601 1.57e-184 - - - S - - - Phosphotransferase enzyme family
EHHPBMKL_01602 8.01e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EHHPBMKL_01603 1.47e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHHPBMKL_01604 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EHHPBMKL_01605 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EHHPBMKL_01606 3.41e-80 ylqD - - S - - - YlqD protein
EHHPBMKL_01607 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHHPBMKL_01608 5.67e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EHHPBMKL_01609 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EHHPBMKL_01610 5.09e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHHPBMKL_01611 3.37e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHHPBMKL_01612 0.0 ylqG - - - - - - -
EHHPBMKL_01613 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
EHHPBMKL_01614 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EHHPBMKL_01615 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EHHPBMKL_01616 7.32e-216 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
EHHPBMKL_01617 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHHPBMKL_01618 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EHHPBMKL_01619 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
EHHPBMKL_01620 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHHPBMKL_01621 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHHPBMKL_01622 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EHHPBMKL_01623 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EHHPBMKL_01624 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
EHHPBMKL_01625 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
EHHPBMKL_01626 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
EHHPBMKL_01627 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EHHPBMKL_01628 1.96e-122 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
EHHPBMKL_01629 5.19e-309 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EHHPBMKL_01630 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
EHHPBMKL_01631 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
EHHPBMKL_01632 3e-260 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
EHHPBMKL_01633 8.9e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
EHHPBMKL_01634 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
EHHPBMKL_01635 1.81e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
EHHPBMKL_01636 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EHHPBMKL_01637 8.47e-245 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHHPBMKL_01638 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
EHHPBMKL_01639 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
EHHPBMKL_01640 1.48e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
EHHPBMKL_01641 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
EHHPBMKL_01642 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
EHHPBMKL_01643 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHHPBMKL_01644 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHHPBMKL_01645 7.94e-250 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
EHHPBMKL_01646 6.35e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
EHHPBMKL_01647 1.42e-248 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EHHPBMKL_01648 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
EHHPBMKL_01649 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
EHHPBMKL_01650 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EHHPBMKL_01651 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EHHPBMKL_01652 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHPBMKL_01653 5.85e-94 ylxL - - - - - - -
EHHPBMKL_01654 7.07e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EHHPBMKL_01655 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHHPBMKL_01656 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EHHPBMKL_01657 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EHHPBMKL_01658 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHHPBMKL_01659 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EHHPBMKL_01660 2.57e-272 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EHHPBMKL_01661 1.15e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EHHPBMKL_01662 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EHHPBMKL_01663 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHHPBMKL_01664 1.9e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EHHPBMKL_01665 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EHHPBMKL_01666 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
EHHPBMKL_01667 6.16e-63 ylxQ - - J - - - ribosomal protein
EHHPBMKL_01668 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHHPBMKL_01669 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
EHHPBMKL_01670 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHHPBMKL_01671 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHHPBMKL_01672 2.6e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EHHPBMKL_01673 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHHPBMKL_01674 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EHHPBMKL_01675 4.15e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
EHHPBMKL_01676 5.91e-299 mlpA - - S - - - Belongs to the peptidase M16 family
EHHPBMKL_01677 2.17e-56 ymxH - - S - - - YlmC YmxH family
EHHPBMKL_01678 4.51e-204 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
EHHPBMKL_01679 1.36e-137 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EHHPBMKL_01680 1.74e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHHPBMKL_01681 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHHPBMKL_01682 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHHPBMKL_01683 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHHPBMKL_01684 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
EHHPBMKL_01685 6.32e-42 - - - S - - - YlzJ-like protein
EHHPBMKL_01686 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EHHPBMKL_01687 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_01688 3.16e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_01689 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHHPBMKL_01690 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
EHHPBMKL_01691 1.12e-306 albE - - S - - - Peptidase M16
EHHPBMKL_01692 8.28e-310 ymfH - - S - - - zinc protease
EHHPBMKL_01693 2.88e-164 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EHHPBMKL_01694 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
EHHPBMKL_01695 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
EHHPBMKL_01696 5.76e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
EHHPBMKL_01697 9.58e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHHPBMKL_01698 4.64e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EHHPBMKL_01699 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHHPBMKL_01700 5.01e-275 pbpX - - V - - - Beta-lactamase
EHHPBMKL_01701 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EHHPBMKL_01702 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
EHHPBMKL_01703 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
EHHPBMKL_01704 8.3e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EHHPBMKL_01705 7.11e-274 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EHHPBMKL_01706 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHHPBMKL_01707 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
EHHPBMKL_01708 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
EHHPBMKL_01709 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHHPBMKL_01710 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHHPBMKL_01712 1.16e-165 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
EHHPBMKL_01713 1.35e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHHPBMKL_01714 3.7e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
EHHPBMKL_01715 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHHPBMKL_01716 5.27e-49 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
EHHPBMKL_01717 3.63e-309 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
EHHPBMKL_01718 5.05e-186 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
EHHPBMKL_01719 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
EHHPBMKL_01720 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EHHPBMKL_01721 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_01722 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_01723 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EHHPBMKL_01724 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
EHHPBMKL_01725 6.55e-292 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHHPBMKL_01726 4.27e-102 nucB - - M - - - Deoxyribonuclease NucA/NucB
EHHPBMKL_01727 4.46e-153 yoaK - - S - - - Membrane
EHHPBMKL_01728 2.78e-82 ymzB - - - - - - -
EHHPBMKL_01729 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
EHHPBMKL_01730 4.29e-06 - - - - - - - -
EHHPBMKL_01731 5.4e-161 ymaC - - S - - - Replication protein
EHHPBMKL_01732 1.11e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
EHHPBMKL_01733 5.05e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EHHPBMKL_01734 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EHHPBMKL_01736 5.96e-77 ymaF - - S - - - YmaF family
EHHPBMKL_01737 7.32e-219 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHHPBMKL_01738 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EHHPBMKL_01739 2.86e-57 - - - - - - - -
EHHPBMKL_01740 9.42e-29 ymzA - - - - - - -
EHHPBMKL_01741 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
EHHPBMKL_01742 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHHPBMKL_01743 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHHPBMKL_01744 2.24e-141 ymaB - - S - - - MutT family
EHHPBMKL_01745 1.86e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EHHPBMKL_01746 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
EHHPBMKL_01747 2.7e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHHPBMKL_01748 1.01e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EHHPBMKL_01749 4.39e-88 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
EHHPBMKL_01750 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EHHPBMKL_01751 1.03e-28 - - - - - - - -
EHHPBMKL_01752 4.5e-115 - - - - - - - -
EHHPBMKL_01756 2.1e-55 - - - S - - - Protein of unknown function (DUF2568)
EHHPBMKL_01757 4.7e-51 - - - T - - - Histidine kinase
EHHPBMKL_01758 3.19e-265 mrjp - - G - - - Major royal jelly protein
EHHPBMKL_01759 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
EHHPBMKL_01760 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EHHPBMKL_01761 9.04e-278 xylR - - GK - - - ROK family
EHHPBMKL_01762 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
EHHPBMKL_01763 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
EHHPBMKL_01764 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EHHPBMKL_01768 2.21e-27 - - - - - - - -
EHHPBMKL_01769 8.43e-73 dinB - - S - - - DinB family
EHHPBMKL_01770 8.07e-235 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
EHHPBMKL_01771 3.63e-96 - - - S - - - Bacterial transferase hexapeptide (six repeats)
EHHPBMKL_01772 2.78e-24 - - - - - - - -
EHHPBMKL_01774 2.75e-39 - - - - - - - -
EHHPBMKL_01776 1.34e-94 yoaP - - K - - - YoaP-like
EHHPBMKL_01777 1.64e-77 yoaP - - K - - - YoaP-like
EHHPBMKL_01778 3.28e-128 - - - J - - - Acetyltransferase (GNAT) domain
EHHPBMKL_01779 4.55e-139 - - - S - - - Domain of unknown function (DUF3885)
EHHPBMKL_01780 6.88e-257 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHPBMKL_01781 3.33e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
EHHPBMKL_01782 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EHHPBMKL_01785 0.0 yobO - - M - - - Pectate lyase superfamily protein
EHHPBMKL_01786 6.07e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
EHHPBMKL_01787 1.37e-182 yndL - - S - - - Replication protein
EHHPBMKL_01788 1.74e-11 - - - - - - - -
EHHPBMKL_01789 1.04e-183 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
EHHPBMKL_01790 3.2e-95 yndM - - S - - - Protein of unknown function (DUF2512)
EHHPBMKL_01792 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHHPBMKL_01793 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EHHPBMKL_01794 5.22e-145 yneB - - L - - - resolvase
EHHPBMKL_01795 2.33e-43 ynzC - - S - - - UPF0291 protein
EHHPBMKL_01796 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHHPBMKL_01797 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
EHHPBMKL_01798 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
EHHPBMKL_01799 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
EHHPBMKL_01800 3.14e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
EHHPBMKL_01801 7.09e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
EHHPBMKL_01802 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
EHHPBMKL_01803 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
EHHPBMKL_01804 7.01e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
EHHPBMKL_01805 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
EHHPBMKL_01806 1.47e-20 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
EHHPBMKL_01807 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EHHPBMKL_01808 8.17e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHHPBMKL_01810 1.73e-44 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
EHHPBMKL_01811 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
EHHPBMKL_01812 7.79e-70 yneQ - - - - - - -
EHHPBMKL_01813 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
EHHPBMKL_01814 2.6e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EHHPBMKL_01815 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
EHHPBMKL_01816 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHHPBMKL_01817 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHHPBMKL_01818 5.42e-20 - - - - - - - -
EHHPBMKL_01819 1.82e-63 ynfC - - - - - - -
EHHPBMKL_01820 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EHHPBMKL_01821 1.15e-233 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
EHHPBMKL_01822 1.26e-243 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
EHHPBMKL_01823 5.27e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
EHHPBMKL_01824 3.96e-271 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
EHHPBMKL_01825 5.86e-191 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHPBMKL_01826 2.14e-232 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
EHHPBMKL_01827 1.07e-284 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
EHHPBMKL_01828 2e-199 yndG - - S - - - DoxX-like family
EHHPBMKL_01829 4.51e-99 - - - S - - - Domain of unknown function (DUF4166)
EHHPBMKL_01830 0.0 yndJ - - S - - - YndJ-like protein
EHHPBMKL_01831 4.6e-13 yxlH - - EGP - - - Major Facilitator Superfamily
EHHPBMKL_01833 1.44e-270 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
EHHPBMKL_01834 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
EHHPBMKL_01835 1.43e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
EHHPBMKL_01836 5.65e-311 - - - T - - - Histidine kinase
EHHPBMKL_01837 6.28e-163 - - - T - - - Transcriptional regulatory protein, C terminal
EHHPBMKL_01838 8.84e-316 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
EHHPBMKL_01839 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EHHPBMKL_01840 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_01841 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_01842 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_01843 6.75e-288 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHHPBMKL_01844 1.18e-177 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EHHPBMKL_01845 7.47e-156 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EHHPBMKL_01846 8.91e-162 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EHHPBMKL_01847 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
EHHPBMKL_01848 3.74e-284 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHHPBMKL_01849 1.12e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHHPBMKL_01850 7.45e-167 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHHPBMKL_01851 3.25e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EHHPBMKL_01852 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EHHPBMKL_01853 8.7e-184 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EHHPBMKL_01854 2.26e-95 yngA - - S - - - membrane
EHHPBMKL_01855 3.16e-144 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EHHPBMKL_01856 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
EHHPBMKL_01857 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EHHPBMKL_01858 1.67e-176 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
EHHPBMKL_01859 3.48e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
EHHPBMKL_01860 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
EHHPBMKL_01861 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
EHHPBMKL_01862 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHHPBMKL_01863 1.79e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EHHPBMKL_01864 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
EHHPBMKL_01865 1.96e-84 yngL - - S - - - Protein of unknown function (DUF1360)
EHHPBMKL_01866 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
EHHPBMKL_01867 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_01868 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_01869 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_01870 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_01871 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EHHPBMKL_01872 1.16e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EHHPBMKL_01873 7.44e-312 yoeA - - V - - - MATE efflux family protein
EHHPBMKL_01874 2.13e-124 yoeB - - S - - - IseA DL-endopeptidase inhibitor
EHHPBMKL_01876 3.97e-125 - - - L - - - Integrase
EHHPBMKL_01877 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
EHHPBMKL_01878 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EHHPBMKL_01879 1.95e-255 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
EHHPBMKL_01880 3.29e-67 - - - K - - - Helix-turn-helix domain
EHHPBMKL_01881 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHHPBMKL_01882 2.6e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_01883 1.77e-239 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EHHPBMKL_01884 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EHHPBMKL_01885 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
EHHPBMKL_01886 7.8e-207 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_01887 2.82e-259 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHHPBMKL_01888 3.42e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHHPBMKL_01889 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EHHPBMKL_01890 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHPBMKL_01891 3.03e-50 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EHHPBMKL_01892 2.12e-176 yoxB - - - - - - -
EHHPBMKL_01893 1.1e-261 yoaB - - EGP - - - the major facilitator superfamily
EHHPBMKL_01894 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
EHHPBMKL_01895 4.74e-243 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHHPBMKL_01896 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHHPBMKL_01897 2.99e-22 yoaF - - - - - - -
EHHPBMKL_01899 1.63e-128 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHHPBMKL_01900 5.5e-56 - - - - - - - -
EHHPBMKL_01901 3.25e-72 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EHHPBMKL_01902 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EHHPBMKL_01903 1.05e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
EHHPBMKL_01904 9.78e-169 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
EHHPBMKL_01905 8.84e-121 yobS - - K - - - Transcriptional regulator
EHHPBMKL_01906 1.98e-174 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHHPBMKL_01907 1.57e-118 yobW - - - - - - -
EHHPBMKL_01908 6.33e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
EHHPBMKL_01909 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EHHPBMKL_01910 8.99e-116 yozB - - S ko:K08976 - ko00000 membrane
EHHPBMKL_01911 4.8e-179 - - - J - - - Protein required for attachment to host cells
EHHPBMKL_01912 2.27e-123 yocC - - - - - - -
EHHPBMKL_01913 3.72e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
EHHPBMKL_01915 9.79e-168 yocH - - M - - - COG1388 FOG LysM repeat
EHHPBMKL_01916 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHHPBMKL_01917 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHHPBMKL_01919 4.5e-79 yocK - - T - - - general stress protein
EHHPBMKL_01920 2.71e-13 yocL - - - - - - -
EHHPBMKL_01921 4.98e-13 yocN - - - - - - -
EHHPBMKL_01922 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHHPBMKL_01923 1.87e-57 yozN - - - - - - -
EHHPBMKL_01924 6.36e-50 yocN - - - - - - -
EHHPBMKL_01925 5.32e-75 yozO - - S - - - Bacterial PH domain
EHHPBMKL_01927 1.11e-41 yozC - - - - - - -
EHHPBMKL_01928 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHHPBMKL_01929 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
EHHPBMKL_01930 8.22e-213 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
EHHPBMKL_01931 4.17e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EHHPBMKL_01932 2.82e-214 yocS - - S ko:K03453 - ko00000 -transporter
EHHPBMKL_01933 1.98e-179 - - - S - - - Metallo-beta-lactamase superfamily
EHHPBMKL_01934 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EHHPBMKL_01935 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EHHPBMKL_01936 0.0 yojO - - P - - - Von Willebrand factor
EHHPBMKL_01937 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
EHHPBMKL_01938 6.26e-143 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EHHPBMKL_01939 3.47e-287 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EHHPBMKL_01940 1.13e-276 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
EHHPBMKL_01941 4.5e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHHPBMKL_01943 2.39e-310 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
EHHPBMKL_01944 1.68e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHHPBMKL_01945 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
EHHPBMKL_01946 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
EHHPBMKL_01947 5.2e-31 - - - - - - - -
EHHPBMKL_01948 4.91e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
EHHPBMKL_01949 4.87e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
EHHPBMKL_01951 1.5e-88 iolK - - S - - - tautomerase
EHHPBMKL_01952 2.74e-92 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
EHHPBMKL_01953 1.2e-74 yodB - - K - - - transcriptional
EHHPBMKL_01954 1.35e-138 yodC - - C - - - nitroreductase
EHHPBMKL_01955 2.43e-140 yahD - - S ko:K06999 - ko00000 Carboxylesterase
EHHPBMKL_01956 1.09e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EHHPBMKL_01957 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
EHHPBMKL_01958 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHHPBMKL_01959 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
EHHPBMKL_01960 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHHPBMKL_01961 5.86e-168 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_01962 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EHHPBMKL_01963 6.12e-166 yodH - - Q - - - Methyltransferase
EHHPBMKL_01964 6.87e-50 yodI - - - - - - -
EHHPBMKL_01965 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
EHHPBMKL_01966 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
EHHPBMKL_01968 1.16e-72 yodL - - S - - - YodL-like
EHHPBMKL_01969 5.88e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EHHPBMKL_01970 9.77e-34 yozD - - S - - - YozD-like protein
EHHPBMKL_01972 1.9e-161 yodN - - - - - - -
EHHPBMKL_01973 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
EHHPBMKL_01974 8.13e-62 yokU - - S - - - YokU-like protein, putative antitoxin
EHHPBMKL_01975 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
EHHPBMKL_01976 9.87e-204 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
EHHPBMKL_01977 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
EHHPBMKL_01978 4.64e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EHHPBMKL_01979 1.19e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EHHPBMKL_01980 1.69e-312 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHHPBMKL_01981 1.19e-83 - - - L - - - Bacterial transcription activator, effector binding domain
EHHPBMKL_01983 5.71e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
EHHPBMKL_01984 8.84e-316 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
EHHPBMKL_01985 1.64e-62 cgeC - - - ko:K06321 - ko00000 -
EHHPBMKL_01986 3.12e-90 cgeA - - - ko:K06319 - ko00000 -
EHHPBMKL_01987 1.88e-223 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
EHHPBMKL_01988 6.87e-277 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
EHHPBMKL_01989 4.14e-94 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EHHPBMKL_01994 1.24e-50 yoqH - - M - - - LysM domain
EHHPBMKL_01995 6.38e-259 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EHHPBMKL_01997 3.41e-216 - - - S - - - amine dehydrogenase activity
EHHPBMKL_01999 2.6e-66 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EHHPBMKL_02000 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EHHPBMKL_02001 4.26e-109 - - - G - - - SMI1-KNR4 cell-wall
EHHPBMKL_02002 4.29e-109 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
EHHPBMKL_02003 0.0 yokA - - L - - - Recombinase
EHHPBMKL_02004 3.43e-134 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EHHPBMKL_02005 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EHHPBMKL_02006 2.82e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHHPBMKL_02007 3.35e-89 ypoP - - K - - - transcriptional
EHHPBMKL_02008 5.59e-126 ypmS - - S - - - protein conserved in bacteria
EHHPBMKL_02009 6.09e-175 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
EHHPBMKL_02010 2.43e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EHHPBMKL_02011 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
EHHPBMKL_02012 1.42e-307 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EHHPBMKL_02013 5.8e-224 yplP - - K - - - Transcriptional regulator
EHHPBMKL_02014 1.5e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
EHHPBMKL_02015 1.35e-147 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EHHPBMKL_02016 6.07e-117 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHHPBMKL_02017 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHHPBMKL_02018 6.48e-148 ypjP - - S - - - YpjP-like protein
EHHPBMKL_02019 8.22e-171 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
EHHPBMKL_02020 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
EHHPBMKL_02021 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
EHHPBMKL_02022 5.44e-202 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
EHHPBMKL_02023 7.66e-127 yagB - - S ko:K06950 - ko00000 phosphohydrolase
EHHPBMKL_02024 9.26e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
EHHPBMKL_02025 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EHHPBMKL_02026 1.49e-274 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EHHPBMKL_02027 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EHHPBMKL_02028 5.19e-17 degR - - - - - - -
EHHPBMKL_02029 9.27e-49 - - - S - - - Protein of unknown function (DUF2564)
EHHPBMKL_02030 6.59e-40 ypeQ - - S - - - Zinc-finger
EHHPBMKL_02031 2.06e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
EHHPBMKL_02032 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHHPBMKL_02033 7.37e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
EHHPBMKL_02035 3.33e-210 ypcP - - L - - - 5'3' exonuclease
EHHPBMKL_02036 2.44e-10 - - - - - - - -
EHHPBMKL_02037 8.23e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
EHHPBMKL_02038 0.0 ypbR - - S - - - Dynamin family
EHHPBMKL_02039 2.09e-116 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
EHHPBMKL_02040 5.13e-268 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
EHHPBMKL_02041 2.52e-136 - - - J - - - Acetyltransferase (GNAT) domain
EHHPBMKL_02042 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
EHHPBMKL_02043 1.21e-08 - - - S - - - Bacillus cereus group antimicrobial protein
EHHPBMKL_02044 3.79e-131 yrdC - - Q - - - Isochorismatase family
EHHPBMKL_02045 1.05e-05 - - - - - - - -
EHHPBMKL_02046 2.4e-296 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
EHHPBMKL_02047 4.72e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EHHPBMKL_02048 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHHPBMKL_02049 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
EHHPBMKL_02051 6.91e-31 - - - S - - - YpzG-like protein
EHHPBMKL_02052 5.46e-275 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EHHPBMKL_02053 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EHHPBMKL_02054 1.33e-128 ypsA - - S - - - Belongs to the UPF0398 family
EHHPBMKL_02055 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
EHHPBMKL_02057 1.99e-302 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
EHHPBMKL_02058 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EHHPBMKL_02059 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
EHHPBMKL_02060 1.85e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHHPBMKL_02061 1.85e-74 yppG - - S - - - YppG-like protein
EHHPBMKL_02065 0.000542 - - - - ko:K06430 - ko00000 -
EHHPBMKL_02066 4.72e-238 yppC - - S - - - Protein of unknown function (DUF2515)
EHHPBMKL_02067 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EHHPBMKL_02068 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHHPBMKL_02069 1.04e-118 ypoC - - - - - - -
EHHPBMKL_02070 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHHPBMKL_02071 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
EHHPBMKL_02072 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
EHHPBMKL_02073 1.46e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EHHPBMKL_02074 2.27e-103 ypmB - - S - - - protein conserved in bacteria
EHHPBMKL_02075 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
EHHPBMKL_02076 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EHHPBMKL_02077 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EHHPBMKL_02078 1.99e-202 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHHPBMKL_02079 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EHHPBMKL_02080 7.73e-231 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EHHPBMKL_02081 3.99e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EHHPBMKL_02082 2.98e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
EHHPBMKL_02083 7.44e-169 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
EHHPBMKL_02084 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
EHHPBMKL_02085 3.98e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EHHPBMKL_02086 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
EHHPBMKL_02087 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHHPBMKL_02088 5.09e-212 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EHHPBMKL_02089 1.97e-55 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EHHPBMKL_02090 2.05e-182 ypjB - - S - - - sporulation protein
EHHPBMKL_02091 7.24e-134 ypjA - - S - - - membrane
EHHPBMKL_02092 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
EHHPBMKL_02093 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
EHHPBMKL_02094 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
EHHPBMKL_02095 3.34e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
EHHPBMKL_02096 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
EHHPBMKL_02097 1.76e-297 ypiA - - S - - - COG0457 FOG TPR repeat
EHHPBMKL_02098 3.46e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EHHPBMKL_02099 1.24e-260 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
EHHPBMKL_02100 7.15e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHHPBMKL_02101 7.71e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EHHPBMKL_02102 1.42e-289 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EHHPBMKL_02103 2.05e-147 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
EHHPBMKL_02104 2.46e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
EHHPBMKL_02105 2.37e-211 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHHPBMKL_02106 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHHPBMKL_02107 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EHHPBMKL_02108 7.47e-259 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHHPBMKL_02109 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHHPBMKL_02110 3.54e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
EHHPBMKL_02111 8.53e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EHHPBMKL_02112 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EHHPBMKL_02113 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EHHPBMKL_02114 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EHHPBMKL_02115 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EHHPBMKL_02116 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
EHHPBMKL_02117 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EHHPBMKL_02118 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EHHPBMKL_02119 3.4e-173 yphF - - - - - - -
EHHPBMKL_02120 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
EHHPBMKL_02121 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EHHPBMKL_02122 9.53e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EHHPBMKL_02123 6.19e-136 yphA - - - - - - -
EHHPBMKL_02124 1.87e-12 - - - S - - - YpzI-like protein
EHHPBMKL_02125 1.98e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EHHPBMKL_02126 5.73e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EHHPBMKL_02127 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EHHPBMKL_02128 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
EHHPBMKL_02129 3.83e-76 ypfA - - M - - - Flagellar protein YcgR
EHHPBMKL_02130 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
EHHPBMKL_02131 1.92e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
EHHPBMKL_02132 7.48e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
EHHPBMKL_02133 1.85e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
EHHPBMKL_02134 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EHHPBMKL_02135 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EHHPBMKL_02136 1.15e-189 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EHHPBMKL_02137 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
EHHPBMKL_02138 1.5e-132 ypbE - - M - - - Lysin motif
EHHPBMKL_02139 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
EHHPBMKL_02140 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHHPBMKL_02141 7.41e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
EHHPBMKL_02142 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
EHHPBMKL_02143 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EHHPBMKL_02144 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHHPBMKL_02145 5.62e-254 rsiX - - - - - - -
EHHPBMKL_02146 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EHHPBMKL_02147 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_02148 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_02149 4.39e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EHHPBMKL_02150 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
EHHPBMKL_02151 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EHHPBMKL_02152 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EHHPBMKL_02153 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
EHHPBMKL_02154 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
EHHPBMKL_02155 1.62e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHHPBMKL_02156 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
EHHPBMKL_02157 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EHHPBMKL_02158 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EHHPBMKL_02160 4.51e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
EHHPBMKL_02161 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHPBMKL_02162 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EHHPBMKL_02163 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHHPBMKL_02164 3.97e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EHHPBMKL_02165 1.08e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHHPBMKL_02166 4.92e-71 ypuD - - - - - - -
EHHPBMKL_02167 6.56e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHHPBMKL_02168 1.42e-107 ccdC1 - - O - - - Protein of unknown function (DUF1453)
EHHPBMKL_02169 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHHPBMKL_02170 2.11e-197 ypuA - - S - - - Secreted protein
EHHPBMKL_02171 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EHHPBMKL_02172 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
EHHPBMKL_02173 5.32e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
EHHPBMKL_02174 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
EHHPBMKL_02175 8.19e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EHHPBMKL_02176 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EHHPBMKL_02177 3.86e-142 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
EHHPBMKL_02178 7.94e-173 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHPBMKL_02179 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EHHPBMKL_02180 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
EHHPBMKL_02181 1.43e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHHPBMKL_02182 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHHPBMKL_02183 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHHPBMKL_02184 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
EHHPBMKL_02185 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
EHHPBMKL_02186 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EHHPBMKL_02187 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EHHPBMKL_02188 7.07e-40 yqkK - - - - - - -
EHHPBMKL_02189 3.39e-31 - - - - - - - -
EHHPBMKL_02190 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EHHPBMKL_02191 2.4e-311 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EHHPBMKL_02192 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
EHHPBMKL_02193 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
EHHPBMKL_02194 1.34e-74 ansR - - K - - - Transcriptional regulator
EHHPBMKL_02195 6.89e-279 yqxK - - L - - - DNA helicase
EHHPBMKL_02196 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
EHHPBMKL_02197 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
EHHPBMKL_02198 1.08e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EHHPBMKL_02199 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
EHHPBMKL_02200 2.27e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EHHPBMKL_02201 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
EHHPBMKL_02202 2.2e-79 yqkB - - S - - - Belongs to the HesB IscA family
EHHPBMKL_02203 1.76e-224 yqkA - - K - - - GrpB protein
EHHPBMKL_02204 1.71e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
EHHPBMKL_02205 4.67e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
EHHPBMKL_02206 7.74e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHHPBMKL_02207 9.19e-76 - - - S - - - YolD-like protein
EHHPBMKL_02209 2.91e-238 yueF - - S - - - transporter activity
EHHPBMKL_02211 7.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHPBMKL_02212 2.58e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EHHPBMKL_02213 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
EHHPBMKL_02214 2.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHPBMKL_02215 6.83e-224 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHHPBMKL_02216 1.95e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHHPBMKL_02217 1.38e-174 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
EHHPBMKL_02218 5.31e-304 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
EHHPBMKL_02219 1.9e-279 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EHHPBMKL_02220 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EHHPBMKL_02221 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_02222 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_02223 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_02224 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_02225 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_02226 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EHHPBMKL_02227 7.97e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EHHPBMKL_02228 1.85e-312 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHHPBMKL_02231 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EHHPBMKL_02232 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EHHPBMKL_02233 1.42e-196 - - - K - - - LysR substrate binding domain
EHHPBMKL_02234 6.43e-66 - - - S - - - GlpM protein
EHHPBMKL_02235 7.32e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EHHPBMKL_02236 1.29e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EHHPBMKL_02237 3.37e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EHHPBMKL_02238 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHHPBMKL_02239 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHHPBMKL_02240 1.92e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHHPBMKL_02241 1.3e-34 yqzJ - - - - - - -
EHHPBMKL_02242 1.68e-190 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHHPBMKL_02243 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
EHHPBMKL_02244 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EHHPBMKL_02245 1.33e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
EHHPBMKL_02247 3.45e-85 yqjB - - S - - - protein conserved in bacteria
EHHPBMKL_02248 4.58e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
EHHPBMKL_02249 5.72e-52 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHHPBMKL_02250 1.53e-93 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHHPBMKL_02251 4.25e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EHHPBMKL_02252 3.23e-172 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EHHPBMKL_02253 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
EHHPBMKL_02254 4.77e-216 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EHHPBMKL_02255 1.78e-284 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHHPBMKL_02256 9.83e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHHPBMKL_02257 4.56e-221 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHHPBMKL_02258 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHHPBMKL_02259 3.45e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
EHHPBMKL_02260 2.61e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EHHPBMKL_02261 1.67e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
EHHPBMKL_02262 0.0 bkdR - - KT - - - Transcriptional regulator
EHHPBMKL_02263 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
EHHPBMKL_02264 2.32e-204 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHHPBMKL_02265 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
EHHPBMKL_02266 2.52e-263 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EHHPBMKL_02267 2.06e-259 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
EHHPBMKL_02268 4.16e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
EHHPBMKL_02269 2.78e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EHHPBMKL_02270 1.1e-174 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EHHPBMKL_02271 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
EHHPBMKL_02273 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
EHHPBMKL_02274 1.15e-145 - - - K - - - Protein of unknown function (DUF1232)
EHHPBMKL_02276 2.28e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EHHPBMKL_02279 2.48e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHHPBMKL_02280 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EHHPBMKL_02281 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
EHHPBMKL_02282 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EHHPBMKL_02283 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EHHPBMKL_02284 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
EHHPBMKL_02285 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHHPBMKL_02286 9.49e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EHHPBMKL_02287 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHHPBMKL_02288 8.28e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHHPBMKL_02289 8.75e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHHPBMKL_02290 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHHPBMKL_02291 1.36e-87 yqhY - - S - - - protein conserved in bacteria
EHHPBMKL_02292 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EHHPBMKL_02293 4.67e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EHHPBMKL_02294 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
EHHPBMKL_02295 2.35e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
EHHPBMKL_02296 4.27e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
EHHPBMKL_02297 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
EHHPBMKL_02298 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
EHHPBMKL_02299 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
EHHPBMKL_02300 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
EHHPBMKL_02301 1.27e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
EHHPBMKL_02302 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
EHHPBMKL_02303 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHHPBMKL_02304 2.11e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EHHPBMKL_02305 9.4e-117 yqhR - - S - - - Conserved membrane protein YqhR
EHHPBMKL_02306 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
EHHPBMKL_02307 7.65e-83 yqhP - - - - - - -
EHHPBMKL_02308 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EHHPBMKL_02309 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EHHPBMKL_02310 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EHHPBMKL_02311 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
EHHPBMKL_02312 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHHPBMKL_02313 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHHPBMKL_02314 4.04e-265 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
EHHPBMKL_02315 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EHHPBMKL_02316 8.78e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
EHHPBMKL_02317 2.71e-31 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
EHHPBMKL_02318 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
EHHPBMKL_02319 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
EHHPBMKL_02320 3.13e-101 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
EHHPBMKL_02321 1.28e-153 yqxM - - - ko:K19433 - ko00000 -
EHHPBMKL_02322 2.8e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
EHHPBMKL_02323 8.16e-36 yqzE - - S - - - YqzE-like protein
EHHPBMKL_02324 2.62e-78 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
EHHPBMKL_02325 2.66e-99 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
EHHPBMKL_02326 3.14e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
EHHPBMKL_02327 2.27e-93 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
EHHPBMKL_02328 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
EHHPBMKL_02329 9.79e-235 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
EHHPBMKL_02330 3.84e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHHPBMKL_02331 2.62e-238 yqxL - - P - - - Mg2 transporter protein
EHHPBMKL_02332 6.23e-303 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHHPBMKL_02333 8.33e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHHPBMKL_02335 1.91e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
EHHPBMKL_02336 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
EHHPBMKL_02337 3.45e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
EHHPBMKL_02338 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
EHHPBMKL_02339 2.99e-65 dglA - - S - - - Thiamine-binding protein
EHHPBMKL_02340 2.4e-258 yqgU - - - - - - -
EHHPBMKL_02341 4.66e-280 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
EHHPBMKL_02342 7.14e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EHHPBMKL_02343 9.1e-39 yqgQ - - S - - - Protein conserved in bacteria
EHHPBMKL_02344 3.61e-276 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EHHPBMKL_02345 5.38e-11 yqgO - - - - - - -
EHHPBMKL_02346 8.62e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHHPBMKL_02347 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EHHPBMKL_02348 3.42e-68 yqzD - - - - - - -
EHHPBMKL_02349 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHHPBMKL_02350 5.46e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EHHPBMKL_02351 5.62e-184 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EHHPBMKL_02352 5.88e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
EHHPBMKL_02353 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EHHPBMKL_02354 2.72e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EHHPBMKL_02355 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
EHHPBMKL_02356 5.56e-288 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
EHHPBMKL_02357 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
EHHPBMKL_02358 1.12e-98 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
EHHPBMKL_02359 1.08e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
EHHPBMKL_02360 8.76e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
EHHPBMKL_02361 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHHPBMKL_02362 3.34e-80 yqfX - - S - - - membrane
EHHPBMKL_02363 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
EHHPBMKL_02364 1.3e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
EHHPBMKL_02365 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHHPBMKL_02366 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
EHHPBMKL_02367 9.96e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHHPBMKL_02368 2.8e-313 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EHHPBMKL_02369 1.77e-78 yqfQ - - S - - - YqfQ-like protein
EHHPBMKL_02370 1.18e-224 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHHPBMKL_02371 6.25e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHHPBMKL_02372 1.72e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EHHPBMKL_02373 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EHHPBMKL_02374 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EHHPBMKL_02375 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EHHPBMKL_02376 5.52e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
EHHPBMKL_02377 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EHHPBMKL_02378 5.89e-145 ccpN - - K - - - CBS domain
EHHPBMKL_02379 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EHHPBMKL_02380 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EHHPBMKL_02381 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EHHPBMKL_02382 6e-24 - - - S - - - YqzL-like protein
EHHPBMKL_02383 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHHPBMKL_02384 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EHHPBMKL_02385 6.41e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EHHPBMKL_02386 4.13e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHHPBMKL_02387 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
EHHPBMKL_02388 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
EHHPBMKL_02389 3.72e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
EHHPBMKL_02390 3.57e-61 yqfC - - S - - - sporulation protein YqfC
EHHPBMKL_02391 1.52e-77 yqfB - - - - - - -
EHHPBMKL_02392 4.78e-177 yqfA - - S - - - UPF0365 protein
EHHPBMKL_02393 1.28e-293 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
EHHPBMKL_02394 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
EHHPBMKL_02395 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EHHPBMKL_02396 1.37e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
EHHPBMKL_02397 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
EHHPBMKL_02398 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EHHPBMKL_02399 1.09e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
EHHPBMKL_02400 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EHHPBMKL_02401 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EHHPBMKL_02402 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHHPBMKL_02403 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EHHPBMKL_02404 3.95e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
EHHPBMKL_02405 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EHHPBMKL_02406 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
EHHPBMKL_02407 2.14e-278 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
EHHPBMKL_02408 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EHHPBMKL_02409 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EHHPBMKL_02410 3.84e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EHHPBMKL_02411 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EHHPBMKL_02412 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EHHPBMKL_02413 2.81e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
EHHPBMKL_02414 1.19e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHHPBMKL_02415 5.67e-177 yqeM - - Q - - - Methyltransferase
EHHPBMKL_02416 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EHHPBMKL_02417 6.89e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
EHHPBMKL_02418 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHHPBMKL_02419 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
EHHPBMKL_02420 1.2e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHHPBMKL_02421 3.23e-271 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EHHPBMKL_02422 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
EHHPBMKL_02424 3.99e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
EHHPBMKL_02425 8.09e-181 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EHHPBMKL_02426 4.93e-138 yqeD - - S - - - SNARE associated Golgi protein
EHHPBMKL_02427 5.88e-32 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EHHPBMKL_02428 3.28e-279 - - - EGP - - - Transmembrane secretion effector
EHHPBMKL_02429 1.67e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHPBMKL_02430 5.83e-35 xkdS - - S - - - Protein of unknown function (DUF2634)
EHHPBMKL_02431 1.62e-140 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EHHPBMKL_02432 1.6e-26 xkdR - - S - - - Protein of unknown function (DUF2577)
EHHPBMKL_02434 1.04e-174 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Aldo/keto reductase family
EHHPBMKL_02435 7.78e-91 - - - K - - - MerR family transcriptional regulator
EHHPBMKL_02436 4.67e-16 - - - - - - - -
EHHPBMKL_02437 3.83e-61 - - - S - - - YjcQ protein
EHHPBMKL_02438 3.43e-77 yjcP - - - - - - -
EHHPBMKL_02439 1.63e-77 yqaQ - - L - - - Transposase
EHHPBMKL_02440 1.03e-60 - - - D - - - nuclear chromosome segregation
EHHPBMKL_02441 2.52e-68 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHPBMKL_02443 1.03e-201 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
EHHPBMKL_02444 2.6e-118 - - - K - - - Transcriptional regulator PadR-like family
EHHPBMKL_02445 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
EHHPBMKL_02446 1.27e-306 yrkQ - - T - - - Histidine kinase
EHHPBMKL_02447 7.69e-159 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
EHHPBMKL_02448 8.05e-278 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EHHPBMKL_02450 2.4e-132 yrkN - - K - - - Acetyltransferase (GNAT) family
EHHPBMKL_02451 5.27e-126 yqaC - - F - - - adenylate kinase activity
EHHPBMKL_02452 4.56e-34 - - - K - - - acetyltransferase
EHHPBMKL_02453 1.95e-282 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_02454 8.64e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
EHHPBMKL_02455 4.76e-121 - - - S - - - DinB family
EHHPBMKL_02456 2.06e-190 supH - - S - - - hydrolase
EHHPBMKL_02457 2.91e-187 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
EHHPBMKL_02458 2.9e-168 - - - K - - - Helix-turn-helix domain, rpiR family
EHHPBMKL_02459 3.44e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHHPBMKL_02460 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_02461 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
EHHPBMKL_02462 2.81e-232 romA - - S - - - Beta-lactamase superfamily domain
EHHPBMKL_02463 1.13e-107 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHHPBMKL_02464 2.17e-210 yybE - - K - - - Transcriptional regulator
EHHPBMKL_02465 9.68e-273 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_02466 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EHHPBMKL_02467 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
EHHPBMKL_02468 9.01e-121 yrhH - - Q - - - methyltransferase
EHHPBMKL_02469 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
EHHPBMKL_02470 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
EHHPBMKL_02471 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
EHHPBMKL_02472 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
EHHPBMKL_02473 6.49e-104 yrhD - - S - - - Protein of unknown function (DUF1641)
EHHPBMKL_02474 1.92e-46 yrhC - - S - - - YrhC-like protein
EHHPBMKL_02475 2.56e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHHPBMKL_02476 1.61e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
EHHPBMKL_02477 8.02e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHHPBMKL_02478 2.83e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
EHHPBMKL_02479 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
EHHPBMKL_02480 2.92e-123 yrrS - - S - - - Protein of unknown function (DUF1510)
EHHPBMKL_02481 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
EHHPBMKL_02482 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EHHPBMKL_02483 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EHHPBMKL_02484 1.09e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
EHHPBMKL_02485 3.64e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
EHHPBMKL_02486 2.32e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
EHHPBMKL_02487 4.67e-258 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHHPBMKL_02488 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
EHHPBMKL_02489 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHHPBMKL_02490 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
EHHPBMKL_02491 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHHPBMKL_02492 1.15e-237 yrrI - - S - - - AI-2E family transporter
EHHPBMKL_02493 4.45e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHHPBMKL_02494 3.14e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EHHPBMKL_02495 1.13e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHHPBMKL_02496 1.54e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHHPBMKL_02497 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
EHHPBMKL_02498 8.4e-42 yrzR - - - - - - -
EHHPBMKL_02499 3.14e-103 yrrD - - S - - - protein conserved in bacteria
EHHPBMKL_02500 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EHHPBMKL_02501 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
EHHPBMKL_02502 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EHHPBMKL_02503 4.24e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EHHPBMKL_02504 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_02505 7.55e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EHHPBMKL_02506 9.74e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EHHPBMKL_02507 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHHPBMKL_02508 4.97e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EHHPBMKL_02511 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
EHHPBMKL_02512 2.86e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EHHPBMKL_02513 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHHPBMKL_02514 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHHPBMKL_02515 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EHHPBMKL_02516 2.23e-62 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
EHHPBMKL_02517 1.26e-111 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EHHPBMKL_02518 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHHPBMKL_02519 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
EHHPBMKL_02520 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHPBMKL_02521 4.79e-142 yrbG - - S - - - membrane
EHHPBMKL_02522 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
EHHPBMKL_02523 2.09e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
EHHPBMKL_02524 8.2e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EHHPBMKL_02525 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHHPBMKL_02526 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
EHHPBMKL_02527 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EHHPBMKL_02528 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EHHPBMKL_02529 1.21e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
EHHPBMKL_02531 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHHPBMKL_02532 6.31e-250 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
EHHPBMKL_02533 4.96e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHHPBMKL_02534 1.23e-194 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
EHHPBMKL_02535 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
EHHPBMKL_02536 7.79e-283 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EHHPBMKL_02537 1.96e-120 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
EHHPBMKL_02538 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
EHHPBMKL_02539 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
EHHPBMKL_02540 2.89e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHHPBMKL_02541 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
EHHPBMKL_02542 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EHHPBMKL_02543 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
EHHPBMKL_02544 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EHHPBMKL_02545 4.19e-205 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
EHHPBMKL_02546 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EHHPBMKL_02547 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
EHHPBMKL_02548 4.62e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EHHPBMKL_02549 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
EHHPBMKL_02550 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EHHPBMKL_02551 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
EHHPBMKL_02552 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
EHHPBMKL_02553 2.36e-130 maf - - D ko:K06287 - ko00000 septum formation protein Maf
EHHPBMKL_02554 8.52e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
EHHPBMKL_02555 1.27e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EHHPBMKL_02556 2.28e-308 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EHHPBMKL_02557 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EHHPBMKL_02558 4.38e-35 - - - - - - - -
EHHPBMKL_02559 1.89e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHHPBMKL_02560 3.06e-300 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
EHHPBMKL_02561 2.68e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EHHPBMKL_02562 3.43e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
EHHPBMKL_02563 1.56e-181 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EHHPBMKL_02564 5.19e-223 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EHHPBMKL_02565 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
EHHPBMKL_02566 4.36e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHHPBMKL_02567 1.6e-113 ysxD - - - - - - -
EHHPBMKL_02568 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EHHPBMKL_02569 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHHPBMKL_02570 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
EHHPBMKL_02571 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHHPBMKL_02572 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EHHPBMKL_02573 3.33e-241 ysoA - - H - - - Tetratricopeptide repeat
EHHPBMKL_02574 1.53e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHHPBMKL_02575 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHHPBMKL_02576 4.12e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EHHPBMKL_02577 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHHPBMKL_02578 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHHPBMKL_02579 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EHHPBMKL_02580 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EHHPBMKL_02585 9.55e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
EHHPBMKL_02586 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHHPBMKL_02587 1.18e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHHPBMKL_02588 5.21e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
EHHPBMKL_02589 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EHHPBMKL_02590 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHHPBMKL_02591 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_02592 8.94e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
EHHPBMKL_02593 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EHHPBMKL_02594 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EHHPBMKL_02595 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
EHHPBMKL_02596 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
EHHPBMKL_02597 1.74e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHHPBMKL_02598 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EHHPBMKL_02599 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EHHPBMKL_02600 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
EHHPBMKL_02601 2.48e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
EHHPBMKL_02602 1.23e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
EHHPBMKL_02603 1.43e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
EHHPBMKL_02604 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_02605 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHHPBMKL_02606 2.11e-50 ywbB - - S - - - Protein of unknown function (DUF2711)
EHHPBMKL_02607 1.12e-93 ywbB - - S - - - Protein of unknown function (DUF2711)
EHHPBMKL_02608 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
EHHPBMKL_02609 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EHHPBMKL_02610 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
EHHPBMKL_02611 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
EHHPBMKL_02612 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHHPBMKL_02613 3.08e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHHPBMKL_02614 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHHPBMKL_02615 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHHPBMKL_02616 2.2e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHHPBMKL_02617 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
EHHPBMKL_02618 5.07e-261 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
EHHPBMKL_02619 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
EHHPBMKL_02620 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
EHHPBMKL_02621 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
EHHPBMKL_02622 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
EHHPBMKL_02623 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
EHHPBMKL_02624 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
EHHPBMKL_02625 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EHHPBMKL_02626 1.58e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EHHPBMKL_02627 6.57e-180 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
EHHPBMKL_02628 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EHHPBMKL_02629 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
EHHPBMKL_02630 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EHHPBMKL_02631 1.11e-237 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EHHPBMKL_02632 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
EHHPBMKL_02633 6.58e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
EHHPBMKL_02634 1.34e-56 ysdA - - S - - - Membrane
EHHPBMKL_02635 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EHHPBMKL_02636 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EHHPBMKL_02637 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EHHPBMKL_02638 3.1e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EHHPBMKL_02639 1.59e-68 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
EHHPBMKL_02640 1.05e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
EHHPBMKL_02641 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_02642 1.2e-192 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
EHHPBMKL_02643 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHHPBMKL_02644 1.99e-197 ytxC - - S - - - YtxC-like family
EHHPBMKL_02645 1.05e-138 ytxB - - S - - - SNARE associated Golgi protein
EHHPBMKL_02646 2.02e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EHHPBMKL_02647 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
EHHPBMKL_02648 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHHPBMKL_02649 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EHHPBMKL_02650 1.48e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EHHPBMKL_02651 1.69e-89 ytcD - - K - - - Transcriptional regulator
EHHPBMKL_02652 8e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
EHHPBMKL_02653 4.54e-205 ytbE - - S - - - reductase
EHHPBMKL_02654 5.08e-129 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EHHPBMKL_02655 2.84e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
EHHPBMKL_02656 1.64e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EHHPBMKL_02657 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHHPBMKL_02658 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
EHHPBMKL_02659 2.38e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_02660 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
EHHPBMKL_02661 1.08e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
EHHPBMKL_02662 1.42e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EHHPBMKL_02663 1.35e-69 - - - - - - - -
EHHPBMKL_02664 9.5e-84 yjdF3 - - S - - - Protein of unknown function (DUF2992)
EHHPBMKL_02665 5.65e-96 ytwI - - S - - - membrane
EHHPBMKL_02666 4.05e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
EHHPBMKL_02667 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
EHHPBMKL_02668 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EHHPBMKL_02669 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EHHPBMKL_02670 1.15e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EHHPBMKL_02671 8.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHHPBMKL_02672 4.23e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EHHPBMKL_02673 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EHHPBMKL_02674 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
EHHPBMKL_02675 2.64e-114 ytrI - - - - - - -
EHHPBMKL_02676 7.04e-32 - - - - - - - -
EHHPBMKL_02677 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
EHHPBMKL_02678 3.57e-62 ytpI - - S - - - YtpI-like protein
EHHPBMKL_02679 7.89e-304 ytoI - - K - - - transcriptional regulator containing CBS domains
EHHPBMKL_02680 4.16e-166 ytkL - - S - - - Belongs to the UPF0173 family
EHHPBMKL_02681 8.38e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHPBMKL_02683 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EHHPBMKL_02684 2.49e-296 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EHHPBMKL_02685 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
EHHPBMKL_02686 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHHPBMKL_02687 8.37e-232 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
EHHPBMKL_02688 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EHHPBMKL_02689 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
EHHPBMKL_02690 1.22e-154 ytfI - - S - - - Protein of unknown function (DUF2953)
EHHPBMKL_02691 2.77e-114 yteJ - - S - - - RDD family
EHHPBMKL_02692 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
EHHPBMKL_02693 2.32e-196 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHHPBMKL_02694 0.0 ytcJ - - S - - - amidohydrolase
EHHPBMKL_02695 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EHHPBMKL_02696 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
EHHPBMKL_02697 2.09e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHHPBMKL_02698 1.12e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EHHPBMKL_02699 9.7e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EHHPBMKL_02700 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EHHPBMKL_02701 1.99e-194 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EHHPBMKL_02702 2.82e-140 yttP - - K - - - Transcriptional regulator
EHHPBMKL_02703 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EHHPBMKL_02704 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
EHHPBMKL_02705 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EHHPBMKL_02706 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHHPBMKL_02707 3.13e-133 yokH - - G - - - SMI1 / KNR4 family
EHHPBMKL_02709 9e-60 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
EHHPBMKL_02710 7.11e-19 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EHHPBMKL_02712 2.3e-23 - - - - - - - -
EHHPBMKL_02713 1.58e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHHPBMKL_02715 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EHHPBMKL_02717 2.39e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
EHHPBMKL_02718 1.43e-192 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHHPBMKL_02719 9.06e-190 - - - K - - - Transcriptional regulator
EHHPBMKL_02720 2.86e-160 ygaZ - - E - - - AzlC protein
EHHPBMKL_02721 8.79e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
EHHPBMKL_02722 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHHPBMKL_02723 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EHHPBMKL_02724 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EHHPBMKL_02725 2.06e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
EHHPBMKL_02726 1.94e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
EHHPBMKL_02727 4.99e-154 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EHHPBMKL_02728 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EHHPBMKL_02729 1.39e-233 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EHHPBMKL_02730 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EHHPBMKL_02731 1.19e-57 ytxJ - - O - - - Protein of unknown function (DUF2847)
EHHPBMKL_02732 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
EHHPBMKL_02733 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EHHPBMKL_02734 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EHHPBMKL_02735 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EHHPBMKL_02736 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHHPBMKL_02737 2.4e-190 ytpQ - - S - - - Belongs to the UPF0354 family
EHHPBMKL_02738 5.47e-76 ytpP - - CO - - - Thioredoxin
EHHPBMKL_02739 1.94e-100 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
EHHPBMKL_02740 5.06e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
EHHPBMKL_02741 9.96e-69 ytzB - - S - - - small secreted protein
EHHPBMKL_02742 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EHHPBMKL_02743 4.38e-208 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EHHPBMKL_02744 1.07e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EHHPBMKL_02745 5.51e-60 ytzH - - S - - - YtzH-like protein
EHHPBMKL_02746 2.93e-199 ytmP - - M - - - Phosphotransferase
EHHPBMKL_02747 1.61e-224 ytlR - - I - - - Diacylglycerol kinase catalytic domain
EHHPBMKL_02748 1.47e-216 ytlQ - - - - - - -
EHHPBMKL_02749 6.34e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EHHPBMKL_02750 6.81e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EHHPBMKL_02751 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
EHHPBMKL_02752 1.48e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
EHHPBMKL_02753 1.75e-276 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
EHHPBMKL_02754 2.58e-163 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHHPBMKL_02755 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
EHHPBMKL_02756 5.02e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EHHPBMKL_02757 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHPBMKL_02758 3.73e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
EHHPBMKL_02759 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
EHHPBMKL_02760 2.14e-36 yteV - - S - - - Sporulation protein Cse60
EHHPBMKL_02761 7.81e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_02762 3.24e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EHHPBMKL_02763 2.44e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHHPBMKL_02764 2.88e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EHHPBMKL_02765 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EHHPBMKL_02766 6.9e-111 - - - M - - - Acetyltransferase (GNAT) domain
EHHPBMKL_02767 3.51e-68 ytwF - - P - - - Sulfurtransferase
EHHPBMKL_02768 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EHHPBMKL_02769 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
EHHPBMKL_02770 4.59e-175 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EHHPBMKL_02771 3.35e-269 yttB - - EGP - - - Major facilitator superfamily
EHHPBMKL_02772 1.55e-162 ywaF - - S - - - Integral membrane protein
EHHPBMKL_02773 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
EHHPBMKL_02774 4.63e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_02775 6.12e-222 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
EHHPBMKL_02776 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_02777 4.75e-288 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EHHPBMKL_02778 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_02779 2.02e-206 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
EHHPBMKL_02780 2.68e-228 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHHPBMKL_02781 4.31e-213 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHHPBMKL_02782 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_02783 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
EHHPBMKL_02784 1.43e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
EHHPBMKL_02785 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
EHHPBMKL_02786 1.26e-136 ytqB - - J - - - Putative rRNA methylase
EHHPBMKL_02788 1.49e-184 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
EHHPBMKL_02789 2.02e-271 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
EHHPBMKL_02790 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
EHHPBMKL_02791 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHHPBMKL_02792 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHHPBMKL_02793 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EHHPBMKL_02794 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHHPBMKL_02795 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHHPBMKL_02796 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
EHHPBMKL_02797 1.84e-188 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EHHPBMKL_02798 1.07e-237 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EHHPBMKL_02799 3.39e-181 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHHPBMKL_02800 5.66e-169 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EHHPBMKL_02801 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EHHPBMKL_02802 1.23e-79 ytkC - - S - - - Bacteriophage holin family
EHHPBMKL_02803 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EHHPBMKL_02805 1.26e-100 ytkA - - S - - - YtkA-like
EHHPBMKL_02806 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EHHPBMKL_02807 8.41e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
EHHPBMKL_02808 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EHHPBMKL_02809 1.23e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EHHPBMKL_02810 4.48e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EHHPBMKL_02811 1.06e-234 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EHHPBMKL_02812 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
EHHPBMKL_02813 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EHHPBMKL_02814 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EHHPBMKL_02815 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHHPBMKL_02816 2.52e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EHHPBMKL_02817 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHHPBMKL_02818 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EHHPBMKL_02819 3.03e-169 yteA - - T - - - COG1734 DnaK suppressor protein
EHHPBMKL_02820 1.82e-102 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
EHHPBMKL_02842 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EHHPBMKL_02844 6.67e-123 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
EHHPBMKL_02845 1.08e-277 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
EHHPBMKL_02846 5.61e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
EHHPBMKL_02847 2.98e-104 yuaE - - S - - - DinB superfamily
EHHPBMKL_02848 6.79e-141 - - - S - - - MOSC domain
EHHPBMKL_02849 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EHHPBMKL_02850 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHHPBMKL_02851 7.09e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
EHHPBMKL_02852 9.28e-121 yuaB - - - - - - -
EHHPBMKL_02853 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EHHPBMKL_02854 2.58e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EHHPBMKL_02855 1.07e-280 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHHPBMKL_02856 3.73e-157 - - - G - - - Cupin
EHHPBMKL_02857 4.37e-68 yjcN - - - - - - -
EHHPBMKL_02859 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EHHPBMKL_02860 9.96e-251 yubA - - S - - - transporter activity
EHHPBMKL_02861 1.29e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EHHPBMKL_02862 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
EHHPBMKL_02863 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHHPBMKL_02864 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHHPBMKL_02865 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHHPBMKL_02866 1.32e-315 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EHHPBMKL_02867 2.22e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
EHHPBMKL_02868 6.59e-55 - - - - - - - -
EHHPBMKL_02869 2.01e-242 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EHHPBMKL_02870 7.72e-98 yugU - - S - - - Uncharacterised protein family UPF0047
EHHPBMKL_02871 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHHPBMKL_02872 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EHHPBMKL_02873 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
EHHPBMKL_02874 2.16e-23 - - - - - - - -
EHHPBMKL_02875 4.93e-35 mstX - - S - - - Membrane-integrating protein Mistic
EHHPBMKL_02876 4.84e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
EHHPBMKL_02877 8.53e-95 yugN - - S - - - YugN-like family
EHHPBMKL_02879 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EHHPBMKL_02880 1.32e-131 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
EHHPBMKL_02881 4.34e-152 ycaC - - Q - - - Isochorismatase family
EHHPBMKL_02882 1.37e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
EHHPBMKL_02883 2.24e-284 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
EHHPBMKL_02884 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
EHHPBMKL_02885 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EHHPBMKL_02886 1.68e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
EHHPBMKL_02887 3.75e-109 alaR - - K - - - Transcriptional regulator
EHHPBMKL_02888 1.64e-199 yugF - - I - - - Hydrolase
EHHPBMKL_02889 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
EHHPBMKL_02890 1.92e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EHHPBMKL_02891 2.88e-289 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_02892 2.81e-88 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
EHHPBMKL_02893 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
EHHPBMKL_02894 3.4e-259 yuxJ - - EGP - - - Major facilitator superfamily
EHHPBMKL_02895 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
EHHPBMKL_02896 5.29e-95 yuxK - - S - - - protein conserved in bacteria
EHHPBMKL_02897 9.25e-101 yufK - - S - - - Family of unknown function (DUF5366)
EHHPBMKL_02898 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EHHPBMKL_02899 6.58e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EHHPBMKL_02900 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
EHHPBMKL_02901 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_02902 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHHPBMKL_02903 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHHPBMKL_02905 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EHHPBMKL_02906 6.3e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHPBMKL_02907 8.54e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHPBMKL_02908 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHPBMKL_02909 1.23e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHPBMKL_02910 5.47e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHPBMKL_02911 1.21e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
EHHPBMKL_02912 4e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
EHHPBMKL_02913 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHPBMKL_02914 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_02916 6.21e-190 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
EHHPBMKL_02917 2.66e-11 - - - S - - - DegQ (SacQ) family
EHHPBMKL_02919 4.23e-67 yuzC - - - - - - -
EHHPBMKL_02920 5.64e-295 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
EHHPBMKL_02921 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHHPBMKL_02922 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
EHHPBMKL_02923 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
EHHPBMKL_02924 5.46e-51 yueH - - S - - - YueH-like protein
EHHPBMKL_02925 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
EHHPBMKL_02926 2.67e-238 yueF - - S - - - transporter activity
EHHPBMKL_02927 2.81e-31 - - - S - - - Protein of unknown function (DUF2642)
EHHPBMKL_02928 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
EHHPBMKL_02929 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHPBMKL_02930 8.01e-102 yueC - - S - - - Family of unknown function (DUF5383)
EHHPBMKL_02931 0.0 yueB - - S - - - type VII secretion protein EsaA
EHHPBMKL_02932 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EHHPBMKL_02933 6.52e-275 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
EHHPBMKL_02934 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
EHHPBMKL_02935 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
EHHPBMKL_02936 1.22e-290 yukF - - QT - - - Transcriptional regulator
EHHPBMKL_02937 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
EHHPBMKL_02938 3.06e-171 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
EHHPBMKL_02939 9.15e-45 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
EHHPBMKL_02940 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_02941 7.94e-220 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
EHHPBMKL_02942 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
EHHPBMKL_02943 3.2e-285 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EHHPBMKL_02944 2.03e-170 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHPBMKL_02945 1.72e-209 eSD - - S ko:K07017 - ko00000 Putative esterase
EHHPBMKL_02946 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
EHHPBMKL_02947 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
EHHPBMKL_02948 8.19e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
EHHPBMKL_02949 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHHPBMKL_02950 8.29e-100 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
EHHPBMKL_02951 9.86e-153 yuiC - - S - - - protein conserved in bacteria
EHHPBMKL_02952 2.45e-45 yuiB - - S - - - Putative membrane protein
EHHPBMKL_02953 3.42e-300 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EHHPBMKL_02954 4.19e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
EHHPBMKL_02956 1.35e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EHHPBMKL_02957 2.32e-39 - - - - - - - -
EHHPBMKL_02958 5.92e-93 - - - CP - - - Membrane
EHHPBMKL_02959 6.54e-157 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHHPBMKL_02961 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
EHHPBMKL_02963 4.15e-122 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
EHHPBMKL_02964 9.01e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHPBMKL_02965 3.25e-81 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
EHHPBMKL_02966 2.25e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHHPBMKL_02967 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHHPBMKL_02968 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
EHHPBMKL_02969 8.47e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EHHPBMKL_02970 1.34e-72 yuzD - - S - - - protein conserved in bacteria
EHHPBMKL_02971 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
EHHPBMKL_02972 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
EHHPBMKL_02973 6.76e-217 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EHHPBMKL_02974 5.41e-250 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHHPBMKL_02975 8.26e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EHHPBMKL_02976 1.55e-250 yutH - - S - - - Spore coat protein
EHHPBMKL_02977 1.75e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EHHPBMKL_02978 1.38e-178 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EHHPBMKL_02979 1.55e-95 yutE - - S - - - Protein of unknown function DUF86
EHHPBMKL_02980 3.71e-62 yutD - - S - - - protein conserved in bacteria
EHHPBMKL_02981 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHHPBMKL_02982 8.24e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
EHHPBMKL_02983 2.75e-167 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
EHHPBMKL_02984 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHHPBMKL_02985 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
EHHPBMKL_02986 1.8e-217 yunF - - S - - - Protein of unknown function DUF72
EHHPBMKL_02987 3.04e-80 - - - S - - - phosphoglycolate phosphatase activity
EHHPBMKL_02988 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EHHPBMKL_02989 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
EHHPBMKL_02990 8.78e-18 yqbD - - L - - - Putative phage serine protease XkdF
EHHPBMKL_02992 2.77e-12 - - - - - - - -
EHHPBMKL_02993 3.55e-30 - - - - - - - -
EHHPBMKL_02994 4.28e-274 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_02995 2.32e-299 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EHHPBMKL_02996 9.02e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EHHPBMKL_02997 4.09e-217 bsn - - L - - - Ribonuclease
EHHPBMKL_02998 4.53e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_02999 4.84e-172 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EHHPBMKL_03000 2.16e-205 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
EHHPBMKL_03001 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EHHPBMKL_03002 1.68e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHHPBMKL_03003 2.12e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EHHPBMKL_03004 1.57e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EHHPBMKL_03005 2.73e-211 - - - K - - - helix_turn_helix, mercury resistance
EHHPBMKL_03007 4.36e-94 - - - - - - - -
EHHPBMKL_03008 1.75e-28 - - - S - - - Sporulation delaying protein SdpA
EHHPBMKL_03010 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
EHHPBMKL_03011 2.72e-261 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
EHHPBMKL_03012 1.16e-48 - - - - - - - -
EHHPBMKL_03014 6.17e-104 yncE - - S - - - Protein of unknown function (DUF2691)
EHHPBMKL_03015 2.94e-200 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EHHPBMKL_03016 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
EHHPBMKL_03017 5.15e-100 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
EHHPBMKL_03018 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHHPBMKL_03019 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
EHHPBMKL_03020 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EHHPBMKL_03021 5.13e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHHPBMKL_03022 9e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
EHHPBMKL_03023 1.91e-134 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
EHHPBMKL_03024 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHHPBMKL_03025 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
EHHPBMKL_03026 1.64e-72 yusE - - CO - - - Thioredoxin
EHHPBMKL_03027 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
EHHPBMKL_03028 1.8e-54 yusG - - S - - - Protein of unknown function (DUF2553)
EHHPBMKL_03029 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EHHPBMKL_03030 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EHHPBMKL_03031 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EHHPBMKL_03032 1.56e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
EHHPBMKL_03033 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
EHHPBMKL_03034 8.5e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EHHPBMKL_03035 3.2e-58 - - - - - - - -
EHHPBMKL_03036 5.21e-71 yusN - - M - - - Coat F domain
EHHPBMKL_03037 1.31e-89 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
EHHPBMKL_03038 0.0 yusP - - P - - - Major facilitator superfamily
EHHPBMKL_03039 1.24e-86 yusQ - - S - - - Tautomerase enzyme
EHHPBMKL_03040 1.81e-169 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHPBMKL_03041 4.52e-202 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
EHHPBMKL_03042 2.31e-201 - - - K - - - Transcriptional regulator
EHHPBMKL_03043 4.14e-176 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
EHHPBMKL_03044 2.83e-239 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHHPBMKL_03045 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
EHHPBMKL_03046 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHHPBMKL_03047 7.61e-60 - - - S - - - YusW-like protein
EHHPBMKL_03048 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
EHHPBMKL_03049 1.29e-195 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHPBMKL_03050 2.39e-102 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EHHPBMKL_03051 1.26e-303 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHHPBMKL_03052 3.7e-163 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_03053 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_03054 2.68e-32 - - - - - - - -
EHHPBMKL_03055 1.8e-200 yuxN - - K - - - Transcriptional regulator
EHHPBMKL_03056 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EHHPBMKL_03057 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
EHHPBMKL_03058 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EHHPBMKL_03059 2.16e-244 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EHHPBMKL_03060 2.93e-260 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
EHHPBMKL_03061 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHPBMKL_03062 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_03063 2.99e-162 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
EHHPBMKL_03064 1.43e-192 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
EHHPBMKL_03065 9.74e-134 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EHHPBMKL_03066 3.14e-66 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
EHHPBMKL_03067 2.77e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_03068 1.54e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
EHHPBMKL_03069 3.18e-281 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EHHPBMKL_03070 7.3e-227 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHPBMKL_03071 1.93e-214 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHHPBMKL_03072 8.63e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHPBMKL_03073 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
EHHPBMKL_03074 0.0 yvrG - - T - - - Histidine kinase
EHHPBMKL_03075 7.74e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_03076 1.67e-50 - - - - - - - -
EHHPBMKL_03077 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
EHHPBMKL_03078 1.88e-21 - - - S - - - YvrJ protein family
EHHPBMKL_03079 8.91e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EHHPBMKL_03080 8.36e-89 yvrL - - S - - - Regulatory protein YrvL
EHHPBMKL_03081 1.39e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHHPBMKL_03082 2.27e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHPBMKL_03083 3.29e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHPBMKL_03084 1.28e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHHPBMKL_03085 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EHHPBMKL_03086 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
EHHPBMKL_03087 4.11e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
EHHPBMKL_03088 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
EHHPBMKL_03089 3.88e-211 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
EHHPBMKL_03090 1.95e-178 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
EHHPBMKL_03091 2.33e-126 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
EHHPBMKL_03092 4.32e-148 yfiK - - K - - - Regulator
EHHPBMKL_03093 7.24e-245 - - - T - - - Histidine kinase
EHHPBMKL_03094 1.66e-218 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
EHHPBMKL_03095 1.22e-249 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
EHHPBMKL_03096 5.2e-255 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EHHPBMKL_03097 7.23e-200 yvgN - - S - - - reductase
EHHPBMKL_03098 1.32e-111 yvgO - - - - - - -
EHHPBMKL_03099 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
EHHPBMKL_03100 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EHHPBMKL_03101 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHHPBMKL_03102 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHHPBMKL_03103 1.3e-138 yvgT - - S - - - membrane
EHHPBMKL_03104 1.1e-189 - - - S - - - Metallo-peptidase family M12
EHHPBMKL_03105 3.05e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
EHHPBMKL_03106 1.84e-137 bdbD - - O - - - Thioredoxin
EHHPBMKL_03107 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EHHPBMKL_03108 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EHHPBMKL_03109 1.88e-39 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
EHHPBMKL_03110 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
EHHPBMKL_03111 9.62e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EHHPBMKL_03112 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHHPBMKL_03113 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHPBMKL_03114 3.52e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
EHHPBMKL_03115 3.54e-232 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHPBMKL_03116 8.64e-179 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EHHPBMKL_03117 2.36e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHHPBMKL_03118 7.29e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHHPBMKL_03119 2.91e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EHHPBMKL_03120 5.65e-166 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EHHPBMKL_03121 3.69e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EHHPBMKL_03122 3.82e-204 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
EHHPBMKL_03123 1.13e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHPBMKL_03125 1.88e-06 - - - L - - - AAA ATPase domain
EHHPBMKL_03128 1.06e-39 - - - S - - - Phage integrase family
EHHPBMKL_03130 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHHPBMKL_03131 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EHHPBMKL_03132 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
EHHPBMKL_03133 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
EHHPBMKL_03134 1.64e-47 yvzC - - K - - - transcriptional
EHHPBMKL_03135 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
EHHPBMKL_03136 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EHHPBMKL_03137 2.44e-69 yvaP - - K - - - transcriptional
EHHPBMKL_03138 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
EHHPBMKL_03139 1.34e-158 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
EHHPBMKL_03140 6.04e-173 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHHPBMKL_03141 1.15e-155 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHHPBMKL_03142 1.55e-161 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_03143 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHHPBMKL_03144 1.8e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EHHPBMKL_03145 3.4e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHHPBMKL_03146 1.66e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EHHPBMKL_03147 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EHHPBMKL_03148 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHHPBMKL_03149 4.61e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EHHPBMKL_03150 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EHHPBMKL_03151 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EHHPBMKL_03152 6.82e-128 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EHHPBMKL_03153 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
EHHPBMKL_03154 7.3e-155 yvbI - - M - - - Membrane
EHHPBMKL_03155 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
EHHPBMKL_03156 1.29e-105 yvbK - - K - - - acetyltransferase
EHHPBMKL_03157 2.56e-268 - - - EGP - - - Major facilitator Superfamily
EHHPBMKL_03158 4.84e-229 - - - - - - - -
EHHPBMKL_03159 1.9e-163 - - - S - - - GlcNAc-PI de-N-acetylase
EHHPBMKL_03160 2.89e-185 - - - C - - - WbqC-like protein family
EHHPBMKL_03161 2.95e-187 - - - M - - - Protein involved in cellulose biosynthesis
EHHPBMKL_03162 8.99e-293 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EHHPBMKL_03163 2.36e-217 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
EHHPBMKL_03164 1.83e-277 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EHHPBMKL_03165 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHHPBMKL_03166 1.63e-301 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
EHHPBMKL_03167 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EHHPBMKL_03168 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
EHHPBMKL_03169 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EHHPBMKL_03170 6.6e-276 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EHHPBMKL_03171 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EHHPBMKL_03172 3.44e-239 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EHHPBMKL_03174 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHHPBMKL_03175 4.51e-260 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
EHHPBMKL_03176 1.08e-242 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHPBMKL_03178 1.24e-199 yvbU - - K - - - Transcriptional regulator
EHHPBMKL_03179 6.36e-204 yvbV - - EG - - - EamA-like transporter family
EHHPBMKL_03180 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EHHPBMKL_03181 1.51e-232 yhjM - - K - - - Transcriptional regulator
EHHPBMKL_03182 2.47e-146 - - - S ko:K07149 - ko00000 Membrane
EHHPBMKL_03183 1.79e-214 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EHHPBMKL_03184 1.9e-195 gntR - - K - - - RpiR family transcriptional regulator
EHHPBMKL_03185 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EHHPBMKL_03186 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EHHPBMKL_03187 2.49e-07 - - - S ko:K07483 - ko00000 leucine-zipper of insertion element IS481
EHHPBMKL_03189 1.44e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EHHPBMKL_03190 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EHHPBMKL_03191 3.55e-172 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EHHPBMKL_03192 3.57e-281 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHHPBMKL_03193 3.62e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
EHHPBMKL_03194 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EHHPBMKL_03195 2.67e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EHHPBMKL_03196 4.01e-44 yvfG - - S - - - YvfG protein
EHHPBMKL_03197 2.24e-237 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
EHHPBMKL_03198 1.11e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EHHPBMKL_03199 7.66e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EHHPBMKL_03200 2.73e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EHHPBMKL_03201 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHPBMKL_03202 2.46e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHPBMKL_03203 2.6e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
EHHPBMKL_03204 6.27e-247 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EHHPBMKL_03205 3.44e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
EHHPBMKL_03206 4.98e-272 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EHHPBMKL_03207 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHPBMKL_03208 1.23e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
EHHPBMKL_03209 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EHHPBMKL_03210 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EHHPBMKL_03211 1.17e-155 epsA - - M ko:K19420 - ko00000 biosynthesis protein
EHHPBMKL_03212 1.99e-99 - - - K ko:K19417 - ko00000,ko03000 transcriptional
EHHPBMKL_03213 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
EHHPBMKL_03214 2.32e-126 ywjB - - H - - - RibD C-terminal domain
EHHPBMKL_03215 4.16e-143 yyaS - - S ko:K07149 - ko00000 Membrane
EHHPBMKL_03216 1.9e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHPBMKL_03217 1.01e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
EHHPBMKL_03219 4.22e-51 - - - S - - - Protein of unknown function (DUF1433)
EHHPBMKL_03220 2.29e-52 - - - I - - - Pfam Lipase (class 3)
EHHPBMKL_03221 5e-22 - - - S - - - Protein of unknown function (DUF1433)
EHHPBMKL_03222 0.0 - - - I - - - Pfam Lipase (class 3)
EHHPBMKL_03223 1.31e-45 - - - - - - - -
EHHPBMKL_03225 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EHHPBMKL_03226 4.05e-285 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
EHHPBMKL_03227 3.17e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
EHHPBMKL_03228 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EHHPBMKL_03229 4.27e-120 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EHHPBMKL_03230 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EHHPBMKL_03231 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
EHHPBMKL_03232 3.08e-137 malA - - S - - - Protein of unknown function (DUF1189)
EHHPBMKL_03233 5.29e-178 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
EHHPBMKL_03234 1.1e-279 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
EHHPBMKL_03235 1.49e-261 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
EHHPBMKL_03236 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
EHHPBMKL_03237 2.2e-205 yvdE - - K - - - Transcriptional regulator
EHHPBMKL_03238 8.57e-134 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EHHPBMKL_03239 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
EHHPBMKL_03240 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EHHPBMKL_03241 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EHHPBMKL_03242 1.69e-232 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHHPBMKL_03243 5.54e-105 - - - M - - - Ribonuclease
EHHPBMKL_03244 6.65e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
EHHPBMKL_03245 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
EHHPBMKL_03246 7.32e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EHHPBMKL_03247 1.28e-225 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EHHPBMKL_03248 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EHHPBMKL_03249 2.98e-112 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EHHPBMKL_03250 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EHHPBMKL_03251 4.64e-202 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
EHHPBMKL_03252 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
EHHPBMKL_03253 1.36e-245 sasA - - T - - - Histidine kinase
EHHPBMKL_03254 3.82e-156 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_03255 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EHHPBMKL_03256 9.88e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
EHHPBMKL_03257 8e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EHHPBMKL_03258 2.67e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHHPBMKL_03259 9.83e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHHPBMKL_03260 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
EHHPBMKL_03261 2.72e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHHPBMKL_03262 2.14e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EHHPBMKL_03263 1.22e-269 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EHHPBMKL_03264 5.06e-178 yvpB - - NU - - - protein conserved in bacteria
EHHPBMKL_03265 5.93e-111 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EHHPBMKL_03266 9.48e-157 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EHHPBMKL_03267 5.27e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHHPBMKL_03268 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EHHPBMKL_03269 3.89e-285 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHHPBMKL_03270 6.1e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EHHPBMKL_03271 2.13e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
EHHPBMKL_03272 1.27e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EHHPBMKL_03273 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
EHHPBMKL_03274 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
EHHPBMKL_03275 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
EHHPBMKL_03276 5.54e-219 yvlB - - S - - - Putative adhesin
EHHPBMKL_03277 4.87e-66 yvlA - - - - - - -
EHHPBMKL_03278 3.29e-43 yvkN - - - - - - -
EHHPBMKL_03279 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EHHPBMKL_03280 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EHHPBMKL_03281 2.59e-45 csbA - - S - - - protein conserved in bacteria
EHHPBMKL_03282 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
EHHPBMKL_03283 2.32e-144 yvkB - - K - - - Transcriptional regulator
EHHPBMKL_03284 2.93e-298 yvkA - - P - - - -transporter
EHHPBMKL_03285 1.24e-33 - - - Q - - - Thioesterase domain
EHHPBMKL_03287 9.44e-240 - - - S - - - Psort location CytoplasmicMembrane, score
EHHPBMKL_03288 7.21e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHHPBMKL_03289 2.47e-73 swrA - - S - - - Swarming motility protein
EHHPBMKL_03290 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EHHPBMKL_03291 7.31e-306 ywoF - - P - - - Right handed beta helix region
EHHPBMKL_03292 2.48e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EHHPBMKL_03293 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
EHHPBMKL_03294 5.11e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EHHPBMKL_03295 6.85e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHHPBMKL_03296 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EHHPBMKL_03297 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EHHPBMKL_03298 2.28e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHHPBMKL_03299 1.35e-89 - - - - - - - -
EHHPBMKL_03300 4.35e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
EHHPBMKL_03301 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
EHHPBMKL_03302 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHHPBMKL_03303 6.97e-153 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHHPBMKL_03304 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EHHPBMKL_03305 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EHHPBMKL_03306 2.8e-108 yviE - - - - - - -
EHHPBMKL_03307 1.4e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
EHHPBMKL_03308 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
EHHPBMKL_03309 3.64e-104 yvyG - - NOU - - - FlgN protein
EHHPBMKL_03310 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
EHHPBMKL_03311 5.47e-98 yvyF - - S - - - flagellar protein
EHHPBMKL_03312 1.01e-99 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
EHHPBMKL_03313 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
EHHPBMKL_03314 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EHHPBMKL_03315 1.03e-202 degV - - S - - - protein conserved in bacteria
EHHPBMKL_03316 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHPBMKL_03317 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EHHPBMKL_03318 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
EHHPBMKL_03319 1.16e-235 yvhJ - - K - - - Transcriptional regulator
EHHPBMKL_03320 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EHHPBMKL_03321 4.67e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
EHHPBMKL_03322 4.68e-184 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EHHPBMKL_03323 3.49e-148 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
EHHPBMKL_03324 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
EHHPBMKL_03325 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHHPBMKL_03326 4.87e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
EHHPBMKL_03327 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHPBMKL_03328 4.92e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EHHPBMKL_03329 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EHHPBMKL_03330 0.0 lytB - - D - - - Stage II sporulation protein
EHHPBMKL_03331 1.86e-64 - - - - - - - -
EHHPBMKL_03332 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EHHPBMKL_03333 2.86e-267 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EHHPBMKL_03334 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EHHPBMKL_03335 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EHHPBMKL_03336 1.45e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
EHHPBMKL_03337 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHHPBMKL_03338 0.0 - - - M - - - Glycosyltransferase like family 2
EHHPBMKL_03339 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
EHHPBMKL_03340 2.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EHHPBMKL_03341 2.57e-272 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHHPBMKL_03342 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EHHPBMKL_03343 1.07e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHHPBMKL_03344 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EHHPBMKL_03345 1.66e-249 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EHHPBMKL_03346 8.96e-274 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
EHHPBMKL_03347 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
EHHPBMKL_03348 1.99e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHHPBMKL_03349 1.14e-229 ywtF_2 - - K - - - Transcriptional regulator
EHHPBMKL_03350 6.43e-203 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EHHPBMKL_03351 6.84e-74 yttA - - S - - - Pfam Transposase IS66
EHHPBMKL_03352 6.43e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EHHPBMKL_03353 4.04e-29 ywtC - - - - - - -
EHHPBMKL_03354 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EHHPBMKL_03355 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
EHHPBMKL_03356 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
EHHPBMKL_03358 1.26e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
EHHPBMKL_03359 1.03e-245 - - - E - - - Spore germination protein
EHHPBMKL_03360 5.06e-260 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
EHHPBMKL_03361 3.66e-229 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
EHHPBMKL_03362 2.94e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHHPBMKL_03363 1.38e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EHHPBMKL_03364 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EHHPBMKL_03365 4.4e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHHPBMKL_03366 1.15e-206 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
EHHPBMKL_03367 2.39e-115 batE - - T - - - Sh3 type 3 domain protein
EHHPBMKL_03368 1.75e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
EHHPBMKL_03369 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
EHHPBMKL_03370 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EHHPBMKL_03371 5.35e-215 alsR - - K - - - LysR substrate binding domain
EHHPBMKL_03373 1.04e-306 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EHHPBMKL_03374 3.43e-163 ywrJ - - - - - - -
EHHPBMKL_03375 2.49e-183 cotB - - - ko:K06325 - ko00000 -
EHHPBMKL_03376 5.34e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
EHHPBMKL_03377 6.3e-22 - - - - - - - -
EHHPBMKL_03378 2.33e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EHHPBMKL_03379 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EHHPBMKL_03380 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EHHPBMKL_03381 2e-130 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
EHHPBMKL_03382 2.47e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
EHHPBMKL_03384 2.58e-121 ywqN - - S - - - NAD(P)H-dependent
EHHPBMKL_03385 5.92e-203 - - - K - - - Transcriptional regulator
EHHPBMKL_03386 4.84e-170 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EHHPBMKL_03387 7.58e-123 - - - - - - - -
EHHPBMKL_03389 1.66e-65 - - - - - - - -
EHHPBMKL_03390 5.28e-113 - - - - - - - -
EHHPBMKL_03391 0.0 ywqJ - - S - - - Pre-toxin TG
EHHPBMKL_03392 2.97e-50 ywqI - - S - - - Family of unknown function (DUF5344)
EHHPBMKL_03395 1.2e-191 ywqG - - S - - - Domain of unknown function (DUF1963)
EHHPBMKL_03396 8.72e-314 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHHPBMKL_03397 5.03e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
EHHPBMKL_03398 2.12e-155 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EHHPBMKL_03399 8.29e-151 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
EHHPBMKL_03400 1.74e-21 - - - - - - - -
EHHPBMKL_03401 0.0 ywqB - - S - - - SWIM zinc finger
EHHPBMKL_03402 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EHHPBMKL_03403 1.51e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EHHPBMKL_03404 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
EHHPBMKL_03405 1.47e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
EHHPBMKL_03406 4.49e-82 ywpG - - - - - - -
EHHPBMKL_03407 1.52e-89 ywpF - - S - - - YwpF-like protein
EHHPBMKL_03408 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EHHPBMKL_03409 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EHHPBMKL_03410 1.34e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
EHHPBMKL_03411 4.45e-186 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EHHPBMKL_03412 2e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EHHPBMKL_03413 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
EHHPBMKL_03414 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
EHHPBMKL_03415 3.58e-93 ywoH - - K - - - transcriptional
EHHPBMKL_03416 4.1e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EHHPBMKL_03417 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
EHHPBMKL_03418 2.31e-311 ywoD - - EGP - - - Major facilitator superfamily
EHHPBMKL_03419 1.13e-132 yjgF - - Q - - - Isochorismatase family
EHHPBMKL_03420 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
EHHPBMKL_03421 1.07e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
EHHPBMKL_03422 1.72e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EHHPBMKL_03423 1.17e-131 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
EHHPBMKL_03424 4.67e-95 ywnJ - - S - - - VanZ like family
EHHPBMKL_03425 2.17e-187 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EHHPBMKL_03426 2.76e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
EHHPBMKL_03428 6.01e-89 ywnF - - S - - - Family of unknown function (DUF5392)
EHHPBMKL_03429 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHHPBMKL_03430 6.88e-80 ywnC - - S - - - Family of unknown function (DUF5362)
EHHPBMKL_03431 5.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
EHHPBMKL_03433 3.61e-87 ywnA - - K - - - Transcriptional regulator
EHHPBMKL_03434 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EHHPBMKL_03435 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
EHHPBMKL_03436 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
EHHPBMKL_03437 2.01e-16 csbD - - K - - - CsbD-like
EHHPBMKL_03438 3.66e-108 ywmF - - S - - - Peptidase M50
EHHPBMKL_03439 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EHHPBMKL_03440 3.1e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHHPBMKL_03441 1.06e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHHPBMKL_03443 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EHHPBMKL_03444 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EHHPBMKL_03445 4.93e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
EHHPBMKL_03446 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHHPBMKL_03447 8.35e-175 ywmB - - S - - - TATA-box binding
EHHPBMKL_03448 2.25e-45 ywzB - - S - - - membrane
EHHPBMKL_03449 4.15e-117 ywmA - - - - - - -
EHHPBMKL_03450 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EHHPBMKL_03451 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHHPBMKL_03452 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHHPBMKL_03453 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHHPBMKL_03454 2.77e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHHPBMKL_03455 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EHHPBMKL_03456 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHHPBMKL_03457 3e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EHHPBMKL_03458 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
EHHPBMKL_03459 6.42e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHHPBMKL_03460 1.99e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHHPBMKL_03461 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
EHHPBMKL_03462 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
EHHPBMKL_03463 1.2e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHHPBMKL_03464 1.36e-118 mntP - - P - - - Probably functions as a manganese efflux pump
EHHPBMKL_03465 3.6e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EHHPBMKL_03466 2.02e-97 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
EHHPBMKL_03467 1.88e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
EHHPBMKL_03468 1.71e-78 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EHHPBMKL_03469 1.4e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EHHPBMKL_03470 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHHPBMKL_03471 6.14e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHPBMKL_03472 8.54e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EHHPBMKL_03473 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
EHHPBMKL_03474 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EHHPBMKL_03475 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EHHPBMKL_03476 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
EHHPBMKL_03477 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHHPBMKL_03478 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
EHHPBMKL_03479 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHHPBMKL_03480 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHHPBMKL_03481 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
EHHPBMKL_03482 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
EHHPBMKL_03483 6.67e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
EHHPBMKL_03484 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EHHPBMKL_03485 8.4e-76 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EHHPBMKL_03486 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
EHHPBMKL_03487 6.69e-283 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EHHPBMKL_03488 8.09e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EHHPBMKL_03489 1.13e-58 ywjC - - - - - - -
EHHPBMKL_03490 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHHPBMKL_03491 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHHPBMKL_03492 3.02e-136 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHHPBMKL_03493 2.41e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
EHHPBMKL_03494 1.48e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
EHHPBMKL_03495 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
EHHPBMKL_03496 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHHPBMKL_03497 2.91e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
EHHPBMKL_03498 5.69e-22 ywiC - - S - - - YwiC-like protein
EHHPBMKL_03499 5.43e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
EHHPBMKL_03500 4.27e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EHHPBMKL_03501 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EHHPBMKL_03502 2.21e-94 ywiB - - S - - - protein conserved in bacteria
EHHPBMKL_03504 5.82e-307 ywhL - - CO - - - amine dehydrogenase activity
EHHPBMKL_03505 3.01e-294 ywhK - - CO - - - amine dehydrogenase activity
EHHPBMKL_03506 1.38e-103 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EHHPBMKL_03508 1.73e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EHHPBMKL_03509 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EHHPBMKL_03510 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHHPBMKL_03511 1.23e-69 - - - - - - - -
EHHPBMKL_03512 1.32e-14 - - - - - - - -
EHHPBMKL_03513 1.92e-123 ywhD - - S - - - YwhD family
EHHPBMKL_03514 3.84e-153 ywhC - - S - - - Peptidase family M50
EHHPBMKL_03515 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
EHHPBMKL_03516 4.16e-93 ywhA - - K - - - Transcriptional regulator
EHHPBMKL_03517 9.94e-316 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
EHHPBMKL_03518 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
EHHPBMKL_03519 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
EHHPBMKL_03520 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
EHHPBMKL_03521 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
EHHPBMKL_03522 1.08e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
EHHPBMKL_03523 3.78e-120 - - - S - - - membrane
EHHPBMKL_03524 1.65e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_03525 1.79e-216 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
EHHPBMKL_03528 1.51e-234 - - - - - - - -
EHHPBMKL_03530 8.76e-202 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EHHPBMKL_03531 4.54e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
EHHPBMKL_03532 9.79e-213 - - - S - - - Conserved hypothetical protein 698
EHHPBMKL_03533 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
EHHPBMKL_03534 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
EHHPBMKL_03535 2.94e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
EHHPBMKL_03536 2.21e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
EHHPBMKL_03537 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
EHHPBMKL_03538 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EHHPBMKL_03539 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHPBMKL_03540 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EHHPBMKL_03541 3.85e-144 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EHHPBMKL_03542 1.11e-283 ywfA - - EGP - - - -transporter
EHHPBMKL_03543 2.43e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EHHPBMKL_03544 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHHPBMKL_03545 0.0 rocB - - E - - - arginine degradation protein
EHHPBMKL_03546 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EHHPBMKL_03547 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EHHPBMKL_03548 2.04e-203 - - - T - - - Histidine kinase
EHHPBMKL_03549 6.09e-161 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_03550 2.37e-96 - - - - - - - -
EHHPBMKL_03551 1.48e-153 - - - S - - - ABC-2 family transporter protein
EHHPBMKL_03552 1.32e-221 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_03553 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
EHHPBMKL_03554 4.55e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EHHPBMKL_03555 6.14e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EHHPBMKL_03556 1.63e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EHHPBMKL_03557 5.91e-235 spsG - - M - - - Spore Coat
EHHPBMKL_03558 9.7e-172 spsF - - M ko:K07257 - ko00000 Spore Coat
EHHPBMKL_03559 7.09e-274 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
EHHPBMKL_03560 6.71e-206 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
EHHPBMKL_03561 3.57e-282 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EHHPBMKL_03562 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
EHHPBMKL_03563 5.24e-183 spsA - - M - - - Spore Coat
EHHPBMKL_03564 6.51e-88 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EHHPBMKL_03565 2.17e-76 ywdK - - S - - - small membrane protein
EHHPBMKL_03566 5.38e-291 ywdJ - - F - - - Xanthine uracil
EHHPBMKL_03567 1.06e-60 ywdI - - S - - - Family of unknown function (DUF5327)
EHHPBMKL_03568 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHHPBMKL_03569 3.29e-192 ywdF - - S - - - Glycosyltransferase like family 2
EHHPBMKL_03571 7.67e-85 ywdD - - - - - - -
EHHPBMKL_03573 1.32e-74 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
EHHPBMKL_03574 3.39e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EHHPBMKL_03575 3.52e-26 ywdA - - - - - - -
EHHPBMKL_03576 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EHHPBMKL_03577 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_03578 4.68e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EHHPBMKL_03580 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHHPBMKL_03581 1.34e-235 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHPBMKL_03582 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
EHHPBMKL_03583 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EHHPBMKL_03584 1.24e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
EHHPBMKL_03585 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
EHHPBMKL_03586 6.76e-84 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EHHPBMKL_03587 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EHHPBMKL_03588 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHHPBMKL_03589 3.14e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EHHPBMKL_03590 5.74e-48 ydaS - - S - - - membrane
EHHPBMKL_03591 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EHHPBMKL_03592 4.22e-288 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHHPBMKL_03593 2e-80 gtcA - - S - - - GtrA-like protein
EHHPBMKL_03594 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
EHHPBMKL_03596 7.2e-166 - - - H - - - Methionine biosynthesis protein MetW
EHHPBMKL_03597 1.58e-168 - - - S - - - Streptomycin biosynthesis protein StrF
EHHPBMKL_03598 3.09e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EHHPBMKL_03599 5.15e-308 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
EHHPBMKL_03600 5.8e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EHHPBMKL_03601 1.02e-172 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHHPBMKL_03602 4.83e-202 ywbI - - K - - - Transcriptional regulator
EHHPBMKL_03603 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EHHPBMKL_03604 6.47e-144 ywbG - - M - - - effector of murein hydrolase
EHHPBMKL_03605 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
EHHPBMKL_03606 1.01e-174 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
EHHPBMKL_03607 9.24e-217 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
EHHPBMKL_03608 5.11e-285 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
EHHPBMKL_03609 1.06e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
EHHPBMKL_03610 2.71e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHHPBMKL_03611 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHHPBMKL_03612 3.64e-208 gspA - - M - - - General stress
EHHPBMKL_03613 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
EHHPBMKL_03614 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
EHHPBMKL_03615 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
EHHPBMKL_03616 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_03617 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
EHHPBMKL_03618 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHPBMKL_03619 4.21e-287 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EHHPBMKL_03620 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EHHPBMKL_03621 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EHHPBMKL_03622 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_03623 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHHPBMKL_03624 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
EHHPBMKL_03625 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
EHHPBMKL_03626 1.08e-143 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EHHPBMKL_03627 4.69e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHPBMKL_03628 1.38e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHPBMKL_03629 7.58e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EHHPBMKL_03630 6.17e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
EHHPBMKL_03631 6.3e-291 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EHHPBMKL_03632 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_03633 3.22e-65 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EHHPBMKL_03634 1.41e-302 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHHPBMKL_03635 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHHPBMKL_03636 1.93e-139 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
EHHPBMKL_03637 1.27e-29 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
EHHPBMKL_03638 1.58e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHHPBMKL_03639 8.82e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
EHHPBMKL_03640 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EHHPBMKL_03641 2.26e-245 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
EHHPBMKL_03642 8.52e-314 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
EHHPBMKL_03644 1.81e-127 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EHHPBMKL_03647 7.05e-24 ypdB - - KT ko:K02477,ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EHHPBMKL_03648 0.00047 - - - T - - - helix_turn_helix, Lux Regulon
EHHPBMKL_03649 5.75e-131 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EHHPBMKL_03650 3.43e-77 - - - S - - - COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHHPBMKL_03651 3.07e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHHPBMKL_03652 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
EHHPBMKL_03653 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
EHHPBMKL_03654 1.12e-241 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
EHHPBMKL_03655 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EHHPBMKL_03656 3.19e-287 cimH - - C - - - COG3493 Na citrate symporter
EHHPBMKL_03657 8.1e-199 yxkH - - G - - - Polysaccharide deacetylase
EHHPBMKL_03658 2.62e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHHPBMKL_03659 2.63e-208 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
EHHPBMKL_03660 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHHPBMKL_03661 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
EHHPBMKL_03662 2.28e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EHHPBMKL_03663 6.94e-302 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EHHPBMKL_03666 6.11e-111 yxjI - - S - - - LURP-one-related
EHHPBMKL_03667 6.59e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EHHPBMKL_03668 1.83e-163 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
EHHPBMKL_03669 9.51e-267 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHHPBMKL_03670 8.8e-125 - - - T - - - Domain of unknown function (DUF4163)
EHHPBMKL_03671 2.68e-67 yxiS - - - - - - -
EHHPBMKL_03672 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EHHPBMKL_03673 1.35e-282 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EHHPBMKL_03674 1.91e-183 bglS - - M - - - licheninase activity
EHHPBMKL_03675 1e-279 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
EHHPBMKL_03676 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EHHPBMKL_03677 1.05e-254 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EHHPBMKL_03678 8.44e-208 yxxF - - EG - - - EamA-like transporter family
EHHPBMKL_03679 1.41e-93 yxiE - - T - - - Belongs to the universal stress protein A family
EHHPBMKL_03682 7.64e-53 - - - K - - - Transcriptional regulator
EHHPBMKL_03684 4.69e-39 - - - - - - - -
EHHPBMKL_03685 5.71e-130 - - - L - - - Replication protein
EHHPBMKL_03686 1.86e-18 - - - S - - - Domain of unknown function (DUF5082)
EHHPBMKL_03687 5.59e-58 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
EHHPBMKL_03688 3.9e-232 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
EHHPBMKL_03689 4.36e-225 - - - L - - - AlwI restriction endonuclease
EHHPBMKL_03691 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EHHPBMKL_03692 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EHHPBMKL_03693 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
EHHPBMKL_03694 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHHPBMKL_03695 3.7e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
EHHPBMKL_03696 1.32e-222 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EHHPBMKL_03697 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHHPBMKL_03698 1.1e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
EHHPBMKL_03699 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHHPBMKL_03700 1.17e-144 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHHPBMKL_03701 1.12e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EHHPBMKL_03702 2.32e-193 yxeH - - S - - - hydrolases of the HAD superfamily
EHHPBMKL_03705 9.43e-34 yxeE - - - - - - -
EHHPBMKL_03706 6.89e-08 yxeD - - - - - - -
EHHPBMKL_03707 2.27e-08 - - - L - - - Helix-hairpin-helix motif
EHHPBMKL_03708 1.61e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EHHPBMKL_03709 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
EHHPBMKL_03710 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EHHPBMKL_03711 6.61e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_03712 4.59e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_03713 1.09e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_03714 0.0 - - - T - - - Histidine kinase
EHHPBMKL_03715 1.51e-174 yvrH - - T - - - Transcriptional regulator
EHHPBMKL_03716 7.54e-211 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHHPBMKL_03717 9.21e-166 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
EHHPBMKL_03718 1.05e-167 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EHHPBMKL_03719 1.35e-202 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EHHPBMKL_03720 2.68e-192 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EHHPBMKL_03721 6.24e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
EHHPBMKL_03722 6.3e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EHHPBMKL_03723 1.23e-292 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
EHHPBMKL_03724 4.62e-223 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EHHPBMKL_03725 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EHHPBMKL_03726 5.42e-229 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EHHPBMKL_03727 3.45e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EHHPBMKL_03728 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHHPBMKL_03729 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EHHPBMKL_03730 3.94e-221 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
EHHPBMKL_03731 4.5e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EHHPBMKL_03732 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
EHHPBMKL_03734 5.9e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EHHPBMKL_03735 3.72e-132 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHPBMKL_03736 4.12e-255 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_03737 1.01e-254 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EHHPBMKL_03738 5.42e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
EHHPBMKL_03739 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHHPBMKL_03740 1.58e-187 yxaL - - S - - - PQQ-like domain
EHHPBMKL_03741 2.5e-85 - - - S - - - Family of unknown function (DUF5391)
EHHPBMKL_03742 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EHHPBMKL_03743 7.67e-256 - - - EGP - - - Major Facilitator Superfamily
EHHPBMKL_03744 7.8e-97 yxaI - - S - - - membrane protein domain
EHHPBMKL_03745 2.59e-160 - - - E - - - Ring-cleavage extradiol dioxygenase
EHHPBMKL_03746 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
EHHPBMKL_03747 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
EHHPBMKL_03748 3.95e-292 - - - S - - - Fic/DOC family
EHHPBMKL_03749 1.51e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EHHPBMKL_03750 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
EHHPBMKL_03751 4.92e-110 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EHHPBMKL_03752 1.91e-197 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EHHPBMKL_03753 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EHHPBMKL_03754 3.46e-77 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EHHPBMKL_03755 3.73e-119 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
EHHPBMKL_03756 1.03e-237 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EHHPBMKL_03757 9.35e-233 - - - S - - - Fusaric acid resistance protein-like
EHHPBMKL_03758 5.2e-26 - - - - - - - -
EHHPBMKL_03759 0.0 - - - L - - - AAA domain
EHHPBMKL_03760 8.08e-97 - - - F - - - 5-carbamoylmethyl uridine residue modification
EHHPBMKL_03761 3.12e-116 - - - K - - - NAD+ binding
EHHPBMKL_03762 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHHPBMKL_03765 2.21e-275 yycP - - - - - - -
EHHPBMKL_03766 6.82e-171 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EHHPBMKL_03767 6.14e-233 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EHHPBMKL_03768 2.92e-113 yycN - - K - - - Acetyltransferase
EHHPBMKL_03770 9.49e-262 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
EHHPBMKL_03771 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EHHPBMKL_03772 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHHPBMKL_03773 1.95e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
EHHPBMKL_03774 1.99e-89 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EHHPBMKL_03775 9.38e-58 sdpR - - K - - - transcriptional
EHHPBMKL_03776 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EHHPBMKL_03777 6.44e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
EHHPBMKL_03778 0.0 - - - S - - - ABC transporter
EHHPBMKL_03779 4.27e-257 - - - S - - - Major Facilitator Superfamily
EHHPBMKL_03780 0.0 - - - - - - - -
EHHPBMKL_03781 2.31e-243 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
EHHPBMKL_03782 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EHHPBMKL_03783 2.5e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_03784 1.63e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHHPBMKL_03785 5.69e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EHHPBMKL_03786 2.81e-194 yycI - - S - - - protein conserved in bacteria
EHHPBMKL_03787 0.0 yycH - - S - - - protein conserved in bacteria
EHHPBMKL_03788 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHHPBMKL_03789 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHPBMKL_03794 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHHPBMKL_03795 1.57e-94 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHPBMKL_03796 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EHHPBMKL_03797 7.68e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EHHPBMKL_03799 5.12e-25 yycC - - K - - - YycC-like protein
EHHPBMKL_03800 1.79e-305 - - - M - - - Glycosyltransferase Family 4
EHHPBMKL_03801 6.38e-259 - - - S - - - Ecdysteroid kinase
EHHPBMKL_03802 6.57e-297 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
EHHPBMKL_03803 5.98e-302 - - - M - - - Glycosyltransferase Family 4
EHHPBMKL_03804 2.15e-157 - - - S - - - GlcNAc-PI de-N-acetylase
EHHPBMKL_03805 1.7e-157 - - - KLT - - - COG0515 Serine threonine protein kinase
EHHPBMKL_03806 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EHHPBMKL_03807 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EHHPBMKL_03808 1.95e-201 yybS - - S - - - membrane
EHHPBMKL_03810 3.33e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
EHHPBMKL_03811 4.56e-87 yybR - - K - - - Transcriptional regulator
EHHPBMKL_03812 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
EHHPBMKL_03813 1.02e-197 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EHHPBMKL_03814 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
EHHPBMKL_03815 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EHHPBMKL_03816 3.82e-149 - - - K - - - FCD domain
EHHPBMKL_03817 2.63e-115 - - - S - - - PFAM DinB family protein
EHHPBMKL_03818 5.87e-201 - - - G - - - Major Facilitator Superfamily
EHHPBMKL_03819 1.12e-73 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
EHHPBMKL_03820 1.62e-145 ydgI - - C - - - nitroreductase
EHHPBMKL_03821 2.77e-89 - - - K - - - Winged helix DNA-binding domain
EHHPBMKL_03822 1.48e-191 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EHHPBMKL_03823 1.3e-99 yybA - - K - - - transcriptional
EHHPBMKL_03824 1.49e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
EHHPBMKL_03825 3.34e-211 - - - M - - - Domain of Unknown Function (DUF1259)
EHHPBMKL_03826 4.76e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
EHHPBMKL_03827 4.21e-212 - - - K - - - Transcriptional regulator
EHHPBMKL_03828 2.35e-176 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EHHPBMKL_03829 1.29e-313 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHHPBMKL_03830 6.35e-167 - - - EG - - - EamA-like transporter family
EHHPBMKL_03831 1.53e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EHHPBMKL_03832 1.02e-106 - - - - - - - -
EHHPBMKL_03833 4.54e-91 ynaF - - - - - - -
EHHPBMKL_03836 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EHHPBMKL_03837 2.84e-208 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
EHHPBMKL_03838 1.88e-316 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
EHHPBMKL_03839 4.88e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHPBMKL_03840 6.62e-230 ccpB - - K - - - Transcriptional regulator
EHHPBMKL_03841 3.29e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EHHPBMKL_03842 3.38e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHHPBMKL_03843 3.63e-136 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
EHHPBMKL_03844 4.51e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EHHPBMKL_03845 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EHHPBMKL_03846 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EHHPBMKL_03847 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EHHPBMKL_03848 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHHPBMKL_03849 1.82e-45 yyzM - - S - - - protein conserved in bacteria
EHHPBMKL_03850 4.77e-225 yyaD - - S - - - Membrane
EHHPBMKL_03851 2.62e-105 yhhY - - K - - - FR47-like protein
EHHPBMKL_03852 8.14e-143 yyaC - - S - - - Sporulation protein YyaC
EHHPBMKL_03853 8.27e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EHHPBMKL_03854 1.23e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
EHHPBMKL_03855 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EHHPBMKL_03856 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EHHPBMKL_03857 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EHHPBMKL_03858 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHHPBMKL_03859 7.7e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
EHHPBMKL_03860 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHHPBMKL_03861 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)