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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NPAIPLAM_00001	9.65e-102	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPAIPLAM_00002	1.04e-80	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPAIPLAM_00003	4.32e-163	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPAIPLAM_00004	8.23e-225	-	-	-	D	-	-	-	nuclear chromosome segregation
NPAIPLAM_00005	1.75e-253	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
NPAIPLAM_00006	9.57e-208	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
NPAIPLAM_00007	3.22e-87	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
NPAIPLAM_00008	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPAIPLAM_00012	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NPAIPLAM_00013	5.49e-282	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NPAIPLAM_00014	8.35e-311	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPAIPLAM_00015	4.61e-277	-	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
NPAIPLAM_00016	1.01e-275	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NPAIPLAM_00017	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NPAIPLAM_00018	3.66e-315	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPAIPLAM_00020	4.04e-287	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NPAIPLAM_00021	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NPAIPLAM_00022	1.03e-195	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NPAIPLAM_00023	7.55e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPAIPLAM_00024	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPAIPLAM_00025	5.96e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPAIPLAM_00026	1.27e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPAIPLAM_00027	1.33e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NPAIPLAM_00028	1.28e-101	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
NPAIPLAM_00029	1.03e-158	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NPAIPLAM_00030	9.63e-90	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
NPAIPLAM_00031	6.61e-81	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
NPAIPLAM_00032	1.1e-163	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
NPAIPLAM_00033	3.93e-52	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
NPAIPLAM_00034	1.2e-189	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
NPAIPLAM_00035	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
NPAIPLAM_00036	2.68e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPAIPLAM_00037	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
NPAIPLAM_00038	3.69e-181	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NPAIPLAM_00039	2.53e-113	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPAIPLAM_00040	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NPAIPLAM_00041	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NPAIPLAM_00042	2.66e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NPAIPLAM_00043	7.1e-137	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPAIPLAM_00044	1.82e-16	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPAIPLAM_00045	1.78e-125	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NPAIPLAM_00046	3.23e-194	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NPAIPLAM_00047	3.3e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NPAIPLAM_00048	1.19e-168	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
NPAIPLAM_00049	9.43e-19	-	-	-	L	-	-	-	Integrase core domain protein
NPAIPLAM_00051	2.21e-255	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
NPAIPLAM_00052	1.14e-37	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
NPAIPLAM_00053	7.11e-73	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NPAIPLAM_00054	4.19e-13	-	-	-	-	-	-	-	-
NPAIPLAM_00055	5.38e-47	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
NPAIPLAM_00057	7.89e-08	bamA	-	-	GM	ko:K07277,ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029	domain, Protein
NPAIPLAM_00059	7.82e-239	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPAIPLAM_00061	2.75e-42	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
NPAIPLAM_00062	7.09e-153	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
NPAIPLAM_00063	1.39e-169	XK27_07210	-	-	S	-	-	-	B3 4 domain
NPAIPLAM_00064	7.92e-247	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NPAIPLAM_00065	2.13e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NPAIPLAM_00066	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPAIPLAM_00067	8.51e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPAIPLAM_00068	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPAIPLAM_00069	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPAIPLAM_00070	2.92e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NPAIPLAM_00071	2.04e-273	-	-	-	-	-	-	-	-
NPAIPLAM_00072	4.43e-38	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
NPAIPLAM_00073	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPAIPLAM_00074	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPAIPLAM_00075	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPAIPLAM_00076	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NPAIPLAM_00077	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPAIPLAM_00078	1.06e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NPAIPLAM_00079	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPAIPLAM_00080	3.32e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPAIPLAM_00081	1.77e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPAIPLAM_00082	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPAIPLAM_00083	2.82e-155	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPAIPLAM_00084	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPAIPLAM_00085	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NPAIPLAM_00086	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPAIPLAM_00087	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPAIPLAM_00088	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPAIPLAM_00089	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPAIPLAM_00090	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPAIPLAM_00091	1.27e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPAIPLAM_00092	2.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPAIPLAM_00093	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPAIPLAM_00094	3.59e-113	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPAIPLAM_00095	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NPAIPLAM_00096	3.5e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NPAIPLAM_00097	7.83e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPAIPLAM_00098	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPAIPLAM_00099	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPAIPLAM_00100	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NPAIPLAM_00101	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPAIPLAM_00102	8.02e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPAIPLAM_00103	3.33e-215	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPAIPLAM_00104	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NPAIPLAM_00105	1.5e-193	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPAIPLAM_00106	1.97e-199	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPAIPLAM_00107	5.57e-177	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPAIPLAM_00108	9.19e-187	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPAIPLAM_00109	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPAIPLAM_00110	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NPAIPLAM_00111	1.13e-249	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NPAIPLAM_00112	6.19e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NPAIPLAM_00114	5.59e-290	-	-	-	L	-	-	-	MULE transposase domain
NPAIPLAM_00115	1.86e-294	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NPAIPLAM_00116	8.61e-223	citR	-	-	K	-	-	-	sugar-binding domain protein
NPAIPLAM_00128	3.87e-185	-	-	-	G	-	-	-	Major Facilitator Superfamily
NPAIPLAM_00129	1.15e-06	-	-	-	K	-	-	-	Transcriptional regulator
NPAIPLAM_00131	1.51e-167	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
NPAIPLAM_00132	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NPAIPLAM_00133	3.08e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPAIPLAM_00134	3.89e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPAIPLAM_00135	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPAIPLAM_00136	5.21e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NPAIPLAM_00137	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPAIPLAM_00138	1.65e-113	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NPAIPLAM_00139	1.19e-73	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NPAIPLAM_00140	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
NPAIPLAM_00141	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPAIPLAM_00142	1.13e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPAIPLAM_00143	7.48e-147	-	-	-	S	-	-	-	(CBS) domain
NPAIPLAM_00144	5.83e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NPAIPLAM_00145	2.34e-263	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPAIPLAM_00146	2.79e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPAIPLAM_00147	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPAIPLAM_00148	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPAIPLAM_00149	1.34e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NPAIPLAM_00150	1.66e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NPAIPLAM_00151	6.07e-60	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPAIPLAM_00152	1.54e-157	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NPAIPLAM_00153	1.69e-37	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NPAIPLAM_00154	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NPAIPLAM_00155	4.36e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPAIPLAM_00156	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPAIPLAM_00157	2.16e-97	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPAIPLAM_00158	8.69e-96	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NPAIPLAM_00159	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NPAIPLAM_00160	9.64e-183	yidA	-	-	S	-	-	-	hydrolase
NPAIPLAM_00161	1.77e-76	-	-	-	-	-	-	-	-
NPAIPLAM_00162	4.45e-227	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPAIPLAM_00163	4.7e-300	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPAIPLAM_00164	1.23e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NPAIPLAM_00165	2.81e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
NPAIPLAM_00166	4.67e-122	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NPAIPLAM_00167	6.99e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NPAIPLAM_00168	1.27e-167	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NPAIPLAM_00169	3.15e-38	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NPAIPLAM_00178	1.14e-96	-	-	-	P	-	-	-	ArsC family
NPAIPLAM_00179	1.4e-237	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
NPAIPLAM_00180	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NPAIPLAM_00181	2.91e-96	-	-	-	-	-	-	-	-
NPAIPLAM_00182	1.22e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPAIPLAM_00183	1.55e-65	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NPAIPLAM_00184	1.14e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NPAIPLAM_00185	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NPAIPLAM_00186	4.63e-274	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NPAIPLAM_00187	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NPAIPLAM_00188	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NPAIPLAM_00189	5.91e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPAIPLAM_00190	2.67e-250	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NPAIPLAM_00191	9.47e-124	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NPAIPLAM_00192	1.75e-115	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NPAIPLAM_00193	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NPAIPLAM_00194	1.63e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NPAIPLAM_00195	2.9e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NPAIPLAM_00196	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPAIPLAM_00197	4.24e-19	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NPAIPLAM_00198	7.19e-100	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NPAIPLAM_00199	8.72e-57	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NPAIPLAM_00200	8.64e-72	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NPAIPLAM_00201	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPAIPLAM_00202	2.22e-206	-	-	-	S	-	-	-	Tetratricopeptide repeat
NPAIPLAM_00203	9.97e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPAIPLAM_00204	4.48e-281	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPAIPLAM_00205	8.38e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPAIPLAM_00206	6.24e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NPAIPLAM_00207	1.29e-68	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
NPAIPLAM_00209	1.89e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_00210	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPAIPLAM_00211	9.56e-317	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPAIPLAM_00212	8.64e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPAIPLAM_00213	1.3e-199	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NPAIPLAM_00214	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NPAIPLAM_00215	3.43e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPAIPLAM_00216	2.69e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
NPAIPLAM_00217	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NPAIPLAM_00218	1.05e-182	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPAIPLAM_00219	2.58e-167	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NPAIPLAM_00220	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPAIPLAM_00221	5.38e-167	-	-	-	-	-	-	-	-
NPAIPLAM_00222	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPAIPLAM_00223	3.73e-199	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NPAIPLAM_00225	9.84e-112	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NPAIPLAM_00226	3.54e-116	-	-	-	GM	-	-	-	epimerase
NPAIPLAM_00227	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
NPAIPLAM_00228	1.24e-108	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NPAIPLAM_00229	7.39e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
NPAIPLAM_00230	2.43e-264	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
NPAIPLAM_00231	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPAIPLAM_00232	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPAIPLAM_00233	1.53e-169	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NPAIPLAM_00234	2e-34	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
NPAIPLAM_00235	1.97e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NPAIPLAM_00236	9.38e-58	yodA	-	-	S	-	-	-	Tautomerase enzyme
NPAIPLAM_00237	0.000239	dnrD	-	-	K	ko:K21563	-	ko00000,ko03000	Cyclic nucleotide-monophosphate binding domain
NPAIPLAM_00238	2.4e-151	pnb	-	-	C	-	-	-	nitroreductase
NPAIPLAM_00239	2.85e-107	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
NPAIPLAM_00241	1.25e-10	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
NPAIPLAM_00243	1.81e-59	-	-	-	C	-	-	-	Aldo keto reductase
NPAIPLAM_00244	5.11e-06	-	-	-	S	-	-	-	CsbD-like
NPAIPLAM_00246	7.43e-08	-	-	-	C	-	-	-	Aldo/keto reductase family
NPAIPLAM_00247	2.02e-116	-	-	-	P	-	-	-	Cadmium resistance transporter
NPAIPLAM_00248	6.11e-44	ydzE	-	-	EG	-	-	-	spore germination
NPAIPLAM_00249	4.97e-70	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NPAIPLAM_00250	5.29e-300	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
NPAIPLAM_00251	1.64e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NPAIPLAM_00252	8.34e-101	-	-	-	-	-	-	-	-
NPAIPLAM_00262	8.09e-05	-	-	-	UW	-	-	-	Tetratricopeptide repeat
NPAIPLAM_00263	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NPAIPLAM_00264	2.3e-163	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NPAIPLAM_00265	9.03e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NPAIPLAM_00266	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
NPAIPLAM_00267	1.03e-269	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
NPAIPLAM_00268	0.0	fusA1	-	-	J	-	-	-	elongation factor G
NPAIPLAM_00269	1.71e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPAIPLAM_00270	1.21e-141	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NPAIPLAM_00271	5.72e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPAIPLAM_00272	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NPAIPLAM_00273	1.22e-62	-	-	-	EG	-	-	-	EamA-like transporter family
NPAIPLAM_00274	9.09e-91	-	-	-	EG	-	-	-	EamA-like transporter family
NPAIPLAM_00275	6.71e-243	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
NPAIPLAM_00276	7.89e-236	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NPAIPLAM_00277	5.43e-190	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NPAIPLAM_00278	5.89e-173	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NPAIPLAM_00279	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NPAIPLAM_00280	1.34e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NPAIPLAM_00281	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NPAIPLAM_00282	5.33e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NPAIPLAM_00283	3.68e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NPAIPLAM_00284	8.24e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NPAIPLAM_00285	5.29e-263	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPAIPLAM_00286	1.21e-118	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPAIPLAM_00287	1.95e-92	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NPAIPLAM_00288	2.73e-25	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NPAIPLAM_00289	5.79e-100	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NPAIPLAM_00290	1.08e-11	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NPAIPLAM_00291	1.12e-78	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NPAIPLAM_00292	8.85e-23	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NPAIPLAM_00294	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NPAIPLAM_00296	6.41e-196	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPAIPLAM_00297	2.06e-200	-	-	-	GM	-	-	-	NAD(P)H-binding
NPAIPLAM_00298	1.2e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
NPAIPLAM_00299	6.19e-100	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPAIPLAM_00300	6.9e-62	-	-	-	L	-	-	-	Helix-turn-helix domain
NPAIPLAM_00301	3.14e-114	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NPAIPLAM_00302	4.51e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
NPAIPLAM_00303	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	hydrolase activity, hydrolyzing O-glycosyl compounds
NPAIPLAM_00304	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	L-aspartate oxidase
NPAIPLAM_00305	1.9e-257	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NPAIPLAM_00306	2.74e-231	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	DegT/DnrJ/EryC1/StrS aminotransferase family
NPAIPLAM_00307	6.96e-163	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NPAIPLAM_00308	4.72e-204	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NPAIPLAM_00309	3.43e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPAIPLAM_00310	3.77e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPAIPLAM_00311	4.3e-183	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NPAIPLAM_00312	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPAIPLAM_00313	5.31e-204	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
NPAIPLAM_00314	4.4e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
NPAIPLAM_00315	3.53e-160	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
NPAIPLAM_00316	4.35e-238	-	-	-	-	-	-	-	-
NPAIPLAM_00317	2.36e-287	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NPAIPLAM_00318	1.32e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NPAIPLAM_00319	0.0	-	-	-	L	-	-	-	DNA helicase
NPAIPLAM_00320	3.52e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPAIPLAM_00321	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPAIPLAM_00322	5.69e-13	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPAIPLAM_00323	6.65e-34	-	-	-	K	-	-	-	LysR substrate binding domain
NPAIPLAM_00324	1.04e-130	-	-	-	K	-	-	-	LysR substrate binding domain
NPAIPLAM_00325	1.92e-204	rssA	-	-	S	-	-	-	Phospholipase, patatin family
NPAIPLAM_00326	4.43e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NPAIPLAM_00327	8.6e-235	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
NPAIPLAM_00328	3.54e-45	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPAIPLAM_00329	8.23e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
NPAIPLAM_00330	2.89e-250	flp	-	-	V	-	-	-	Beta-lactamase
NPAIPLAM_00331	1.95e-291	-	-	-	-	-	-	-	-
NPAIPLAM_00333	2.94e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPAIPLAM_00334	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPAIPLAM_00335	6.39e-205	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
NPAIPLAM_00336	1.11e-208	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NPAIPLAM_00337	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPAIPLAM_00339	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NPAIPLAM_00341	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPAIPLAM_00342	1.77e-300	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NPAIPLAM_00344	1.69e-60	-	-	-	S	-	-	-	SNARE associated Golgi protein
NPAIPLAM_00345	3.37e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NPAIPLAM_00346	5.05e-128	-	-	-	K	-	-	-	Virulence activator alpha C-term
NPAIPLAM_00347	1.04e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
NPAIPLAM_00349	1.55e-276	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NPAIPLAM_00351	8.93e-185	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NPAIPLAM_00352	2.24e-39	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPAIPLAM_00353	1.79e-131	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NPAIPLAM_00354	6.24e-244	ampC	-	-	V	-	-	-	Beta-lactamase
NPAIPLAM_00355	4.08e-42	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPAIPLAM_00356	2.89e-287	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPAIPLAM_00357	5.46e-62	-	-	-	-	-	-	-	-
NPAIPLAM_00358	2.15e-180	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
NPAIPLAM_00359	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
NPAIPLAM_00360	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NPAIPLAM_00361	1.53e-207	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPAIPLAM_00362	2.62e-201	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPAIPLAM_00363	1.32e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPAIPLAM_00364	5.2e-293	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPAIPLAM_00365	1.57e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPAIPLAM_00366	2.56e-148	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NPAIPLAM_00367	3.91e-84	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NPAIPLAM_00368	4.51e-164	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
NPAIPLAM_00369	1.28e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NPAIPLAM_00370	4.65e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NPAIPLAM_00371	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPAIPLAM_00372	4.35e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPAIPLAM_00373	3.51e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPAIPLAM_00374	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPAIPLAM_00375	1.78e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPAIPLAM_00376	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPAIPLAM_00377	1.19e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NPAIPLAM_00378	8.07e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NPAIPLAM_00379	2.3e-276	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
NPAIPLAM_00380	9.42e-234	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NPAIPLAM_00381	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NPAIPLAM_00382	1.2e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NPAIPLAM_00384	1.15e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
NPAIPLAM_00385	4.8e-274	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NPAIPLAM_00386	1.09e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPAIPLAM_00387	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPAIPLAM_00388	9.37e-159	-	-	-	S	-	-	-	repeat protein
NPAIPLAM_00389	1.11e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
NPAIPLAM_00390	2.55e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NPAIPLAM_00391	0.0	-	-	-	S	-	-	-	amidohydrolase
NPAIPLAM_00392	4.17e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPAIPLAM_00393	2.64e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NPAIPLAM_00394	1.88e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPAIPLAM_00395	9.41e-09	-	-	-	-	-	-	-	-
NPAIPLAM_00396	1.49e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NPAIPLAM_00397	2.34e-41	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NPAIPLAM_00398	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPAIPLAM_00400	6.19e-143	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
NPAIPLAM_00401	6.85e-184	ylmH	-	-	S	-	-	-	S4 domain protein
NPAIPLAM_00402	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NPAIPLAM_00403	1.01e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPAIPLAM_00404	9.01e-294	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPAIPLAM_00405	1.15e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPAIPLAM_00406	7.39e-191	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPAIPLAM_00407	8.4e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPAIPLAM_00408	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPAIPLAM_00409	2.58e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPAIPLAM_00410	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPAIPLAM_00411	5.05e-13	ftsL	-	-	D	-	-	-	Cell division protein FtsL
NPAIPLAM_00412	2.1e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPAIPLAM_00413	7.65e-104	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NPAIPLAM_00414	9.44e-74	-	-	-	-	-	-	-	-
NPAIPLAM_00415	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NPAIPLAM_00416	5.47e-64	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPAIPLAM_00417	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NPAIPLAM_00418	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NPAIPLAM_00419	9.06e-125	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NPAIPLAM_00420	5.23e-63	-	-	-	-	-	-	-	-
NPAIPLAM_00421	3.78e-271	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPAIPLAM_00422	1.87e-180	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPAIPLAM_00423	1.03e-284	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NPAIPLAM_00424	1.02e-163	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
NPAIPLAM_00425	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NPAIPLAM_00426	1.64e-55	-	-	-	-	-	-	-	-
NPAIPLAM_00427	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NPAIPLAM_00428	4.53e-79	-	-	-	S	-	-	-	Domain of unknown function DUF302
NPAIPLAM_00429	3.83e-198	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPAIPLAM_00430	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NPAIPLAM_00431	1.65e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPAIPLAM_00432	6.88e-46	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NPAIPLAM_00433	1.3e-80	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NPAIPLAM_00434	2.19e-128	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NPAIPLAM_00435	4.92e-233	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPAIPLAM_00436	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NPAIPLAM_00437	1.71e-143	-	-	-	-	-	-	-	-
NPAIPLAM_00438	1.06e-233	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NPAIPLAM_00439	4.79e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPAIPLAM_00440	8.2e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NPAIPLAM_00441	2.94e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NPAIPLAM_00442	3.23e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
NPAIPLAM_00443	1.26e-303	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NPAIPLAM_00444	2.53e-133	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
NPAIPLAM_00445	4.95e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
NPAIPLAM_00447	1.98e-52	-	-	-	-	-	-	-	-
NPAIPLAM_00449	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NPAIPLAM_00450	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NPAIPLAM_00451	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NPAIPLAM_00452	7.44e-230	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPAIPLAM_00453	7.77e-191	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPAIPLAM_00455	7.13e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NPAIPLAM_00456	7.43e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_00457	3.82e-275	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NPAIPLAM_00458	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPAIPLAM_00459	1.96e-75	-	-	-	S	-	-	-	Small secreted protein
NPAIPLAM_00460	1.53e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
NPAIPLAM_00461	2.16e-150	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPAIPLAM_00462	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NPAIPLAM_00463	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NPAIPLAM_00464	1.9e-177	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
NPAIPLAM_00465	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPAIPLAM_00466	7.57e-208	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPAIPLAM_00467	4.85e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPAIPLAM_00468	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPAIPLAM_00469	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
NPAIPLAM_00470	2.66e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NPAIPLAM_00471	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPAIPLAM_00472	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NPAIPLAM_00473	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPAIPLAM_00474	2.58e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NPAIPLAM_00475	2.39e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NPAIPLAM_00476	6.88e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NPAIPLAM_00477	6.57e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NPAIPLAM_00478	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NPAIPLAM_00479	1.62e-120	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPAIPLAM_00480	5.53e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NPAIPLAM_00481	2.79e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPAIPLAM_00482	1.81e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
NPAIPLAM_00483	4.6e-271	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NPAIPLAM_00484	1.61e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NPAIPLAM_00485	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NPAIPLAM_00486	1.38e-155	csrR	-	-	K	-	-	-	response regulator
NPAIPLAM_00487	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPAIPLAM_00488	7.67e-298	-	-	-	V	-	-	-	MatE
NPAIPLAM_00489	6.45e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPAIPLAM_00490	9.25e-196	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPAIPLAM_00491	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NPAIPLAM_00492	1.84e-180	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPAIPLAM_00493	4.08e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPAIPLAM_00494	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NPAIPLAM_00495	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPAIPLAM_00496	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPAIPLAM_00497	5.91e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NPAIPLAM_00498	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPAIPLAM_00499	0.0	-	-	-	S	-	-	-	membrane
NPAIPLAM_00500	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPAIPLAM_00501	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NPAIPLAM_00502	4.45e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPAIPLAM_00503	1.16e-132	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
NPAIPLAM_00504	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NPAIPLAM_00505	1.01e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NPAIPLAM_00506	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NPAIPLAM_00507	2.04e-32	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NPAIPLAM_00508	2.56e-220	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPAIPLAM_00509	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NPAIPLAM_00510	1.37e-18	-	-	-	-	-	-	-	-
NPAIPLAM_00511	1.56e-200	-	-	-	-	-	-	-	-
NPAIPLAM_00512	4.05e-227	-	-	-	-	-	-	-	-
NPAIPLAM_00513	1.1e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
NPAIPLAM_00515	9.09e-149	-	-	-	K	-	-	-	Transcriptional regulator
NPAIPLAM_00516	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NPAIPLAM_00517	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NPAIPLAM_00518	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NPAIPLAM_00519	6.94e-262	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NPAIPLAM_00520	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NPAIPLAM_00521	6.64e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPAIPLAM_00522	1.16e-205	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPAIPLAM_00523	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPAIPLAM_00524	1.64e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPAIPLAM_00525	5.67e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPAIPLAM_00526	1.14e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NPAIPLAM_00527	4.92e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NPAIPLAM_00528	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NPAIPLAM_00530	1.03e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NPAIPLAM_00531	6.37e-60	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPAIPLAM_00532	1.4e-280	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPAIPLAM_00533	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPAIPLAM_00534	9.3e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPAIPLAM_00535	1.06e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPAIPLAM_00536	1.13e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NPAIPLAM_00537	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NPAIPLAM_00538	5.33e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPAIPLAM_00539	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NPAIPLAM_00540	2.51e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NPAIPLAM_00541	5.82e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NPAIPLAM_00542	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NPAIPLAM_00543	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NPAIPLAM_00544	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPAIPLAM_00545	2.1e-213	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPAIPLAM_00546	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPAIPLAM_00547	3.99e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPAIPLAM_00548	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NPAIPLAM_00549	1.13e-260	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPAIPLAM_00550	1.72e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPAIPLAM_00551	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPAIPLAM_00552	1.72e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPAIPLAM_00553	9.89e-207	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
NPAIPLAM_00554	4.17e-236	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPAIPLAM_00555	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NPAIPLAM_00556	2.77e-217	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NPAIPLAM_00557	6.14e-297	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
NPAIPLAM_00558	4.39e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NPAIPLAM_00560	1.32e-170	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_00561	6.23e-192	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NPAIPLAM_00562	5.42e-229	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NPAIPLAM_00563	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NPAIPLAM_00564	3.17e-260	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
NPAIPLAM_00565	8.3e-141	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NPAIPLAM_00566	1.64e-108	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
NPAIPLAM_00567	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPAIPLAM_00568	9.26e-218	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
NPAIPLAM_00569	8.41e-235	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
NPAIPLAM_00570	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NPAIPLAM_00571	5.93e-149	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
NPAIPLAM_00572	2.73e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NPAIPLAM_00573	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPAIPLAM_00574	9.23e-65	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NPAIPLAM_00575	7.67e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NPAIPLAM_00576	1.4e-52	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NPAIPLAM_00577	2.45e-25	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
NPAIPLAM_00578	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
NPAIPLAM_00579	2.76e-182	-	-	-	EG	-	-	-	EamA-like transporter family
NPAIPLAM_00580	2.54e-244	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
NPAIPLAM_00581	1.11e-240	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
NPAIPLAM_00582	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NPAIPLAM_00583	2.14e-110	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NPAIPLAM_00584	1.06e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPAIPLAM_00585	4.45e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NPAIPLAM_00586	6.61e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NPAIPLAM_00587	2e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
NPAIPLAM_00588	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NPAIPLAM_00589	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
NPAIPLAM_00590	4.47e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NPAIPLAM_00591	1e-223	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPAIPLAM_00592	2.41e-235	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPAIPLAM_00593	1.23e-276	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
NPAIPLAM_00594	7.49e-117	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NPAIPLAM_00595	1.51e-241	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
NPAIPLAM_00596	4.62e-119	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NPAIPLAM_00597	6.19e-135	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NPAIPLAM_00598	1.1e-131	-	-	-	-	-	-	-	-
NPAIPLAM_00599	2.67e-272	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NPAIPLAM_00600	2.55e-13	tyrA	4.2.1.51, 5.4.99.5	-	E	ko:K04516,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	chorismate mutase
NPAIPLAM_00601	7.21e-66	-	-	-	G	-	-	-	Major Facilitator Superfamily
NPAIPLAM_00602	3.63e-15	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
NPAIPLAM_00604	2.13e-80	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
NPAIPLAM_00605	3.47e-243	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPAIPLAM_00606	3.38e-170	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
NPAIPLAM_00607	4.19e-41	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
NPAIPLAM_00608	3.41e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPAIPLAM_00609	9.79e-278	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPAIPLAM_00610	4.71e-47	-	-	-	-	-	-	-	-
NPAIPLAM_00611	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
NPAIPLAM_00612	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPAIPLAM_00613	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPAIPLAM_00614	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NPAIPLAM_00615	1.26e-210	-	-	-	C	-	-	-	Aldo keto reductase
NPAIPLAM_00616	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
NPAIPLAM_00617	3.67e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
NPAIPLAM_00618	3.46e-102	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NPAIPLAM_00619	4.19e-33	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NPAIPLAM_00620	8.61e-22	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
NPAIPLAM_00621	7.07e-273	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NPAIPLAM_00622	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPAIPLAM_00623	8.11e-52	-	-	-	S	-	-	-	Cytochrome B5
NPAIPLAM_00627	6.14e-253	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NPAIPLAM_00628	1.91e-08	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NPAIPLAM_00629	2.04e-210	-	-	-	L	-	-	-	Z1 domain
NPAIPLAM_00630	7.41e-150	-	-	-	-	-	-	-	-
NPAIPLAM_00631	3.43e-48	-	-	-	-	-	-	-	-
NPAIPLAM_00632	2.11e-87	-	-	-	-	-	-	-	-
NPAIPLAM_00634	5.54e-177	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
NPAIPLAM_00635	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NPAIPLAM_00636	5.37e-72	-	-	-	S	-	-	-	MazG-like family
NPAIPLAM_00637	5.35e-139	-	-	-	I	-	-	-	PAP2 superfamily
NPAIPLAM_00638	3.01e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NPAIPLAM_00639	5.84e-123	-	-	-	-	-	-	-	-
NPAIPLAM_00640	1.21e-285	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPAIPLAM_00641	1.18e-194	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NPAIPLAM_00642	0.0	yclK	-	-	T	-	-	-	Histidine kinase
NPAIPLAM_00643	1.19e-167	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NPAIPLAM_00644	2.05e-166	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
NPAIPLAM_00646	7.06e-74	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
NPAIPLAM_00647	1.95e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NPAIPLAM_00648	2.38e-164	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
NPAIPLAM_00649	2.22e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPAIPLAM_00650	3.54e-139	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NPAIPLAM_00651	4.44e-44	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NPAIPLAM_00652	2.94e-115	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NPAIPLAM_00653	3.14e-191	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
NPAIPLAM_00654	2.83e-162	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NPAIPLAM_00655	4.12e-209	-	-	-	K	-	-	-	LysR substrate binding domain
NPAIPLAM_00656	2.33e-220	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NPAIPLAM_00657	7.87e-112	lytE	-	-	M	-	-	-	Lysin motif
NPAIPLAM_00658	5.61e-189	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPAIPLAM_00659	8.27e-263	oatA	-	-	I	-	-	-	Acyltransferase
NPAIPLAM_00660	2.55e-68	-	-	-	-	-	-	-	-
NPAIPLAM_00661	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPAIPLAM_00662	1.03e-25	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
NPAIPLAM_00663	1.1e-313	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
NPAIPLAM_00664	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
NPAIPLAM_00666	2.16e-98	uspA3	-	-	T	-	-	-	universal stress protein
NPAIPLAM_00667	3.62e-77	-	-	-	-	-	-	-	-
NPAIPLAM_00668	3.02e-10	-	-	-	-	-	-	-	-
NPAIPLAM_00669	8.75e-200	-	-	-	-	-	-	-	-
NPAIPLAM_00670	4.48e-98	-	-	-	K	-	-	-	Transcriptional regulator
NPAIPLAM_00671	6.93e-236	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NPAIPLAM_00672	1.57e-94	-	-	-	O	-	-	-	OsmC-like protein
NPAIPLAM_00673	5.97e-241	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
NPAIPLAM_00674	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NPAIPLAM_00675	6.26e-23	-	-	-	-	-	-	-	-
NPAIPLAM_00676	3.54e-148	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NPAIPLAM_00677	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_00678	1.66e-130	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NPAIPLAM_00679	3.41e-231	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NPAIPLAM_00680	2.51e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NPAIPLAM_00681	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
NPAIPLAM_00682	9.17e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
NPAIPLAM_00683	8.02e-130	dpsB	-	-	P	-	-	-	Belongs to the Dps family
NPAIPLAM_00684	1.05e-139	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
NPAIPLAM_00685	5.49e-181	-	-	-	G	-	-	-	MucBP domain
NPAIPLAM_00686	2.75e-172	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPAIPLAM_00687	1.81e-207	-	-	-	EG	-	-	-	EamA-like transporter family
NPAIPLAM_00688	2.66e-312	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NPAIPLAM_00691	1.29e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_00692	2.08e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
NPAIPLAM_00693	2.55e-217	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPAIPLAM_00694	1.57e-100	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NPAIPLAM_00695	1.15e-123	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
NPAIPLAM_00696	1.3e-119	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NPAIPLAM_00697	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NPAIPLAM_00698	5e-209	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
NPAIPLAM_00699	2.3e-215	yueF	-	-	S	-	-	-	AI-2E family transporter
NPAIPLAM_00700	6.59e-204	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NPAIPLAM_00701	7.69e-10	-	-	-	-	-	-	-	-
NPAIPLAM_00702	4.03e-114	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
NPAIPLAM_00703	1.71e-68	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPAIPLAM_00704	1.15e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPAIPLAM_00705	1.74e-106	uspA	-	-	T	-	-	-	universal stress protein
NPAIPLAM_00707	6.16e-299	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NPAIPLAM_00708	1.9e-109	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NPAIPLAM_00709	1.2e-95	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
NPAIPLAM_00710	2.68e-172	-	-	-	S	-	-	-	Membrane
NPAIPLAM_00711	6.07e-190	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPAIPLAM_00712	8.61e-35	-	-	-	S	-	-	-	YjcQ protein
NPAIPLAM_00715	5.1e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPAIPLAM_00716	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPAIPLAM_00717	3.37e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NPAIPLAM_00718	2.03e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPAIPLAM_00719	7.61e-276	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
NPAIPLAM_00720	6.39e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NPAIPLAM_00721	3.09e-45	-	-	-	M	-	-	-	LysM domain
NPAIPLAM_00722	8.34e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
NPAIPLAM_00723	1.8e-144	is18	-	-	L	-	-	-	Integrase core domain
NPAIPLAM_00724	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
NPAIPLAM_00725	1.26e-34	-	-	-	-	-	-	-	-
NPAIPLAM_00726	6.3e-218	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
NPAIPLAM_00727	6.83e-194	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
NPAIPLAM_00728	5.47e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NPAIPLAM_00729	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPAIPLAM_00730	4.87e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPAIPLAM_00731	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPAIPLAM_00732	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPAIPLAM_00733	1.32e-248	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NPAIPLAM_00734	2.18e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPAIPLAM_00735	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NPAIPLAM_00736	2.75e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NPAIPLAM_00737	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPAIPLAM_00738	9.51e-284	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPAIPLAM_00739	4.99e-227	-	-	-	-	-	-	-	-
NPAIPLAM_00740	1.52e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
NPAIPLAM_00741	2.58e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
NPAIPLAM_00742	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NPAIPLAM_00743	3.74e-35	-	-	-	EGP	-	-	-	Major Facilitator
NPAIPLAM_00744	6.6e-115	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
NPAIPLAM_00745	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPAIPLAM_00746	4.85e-151	ybbR	-	-	S	-	-	-	YbbR-like protein
NPAIPLAM_00747	1.21e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPAIPLAM_00748	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NPAIPLAM_00749	4e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPAIPLAM_00750	5.51e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPAIPLAM_00751	2.44e-104	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NPAIPLAM_00752	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NPAIPLAM_00753	1.52e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPAIPLAM_00754	2.36e-139	-	-	-	-	-	-	-	-
NPAIPLAM_00755	4.66e-110	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPAIPLAM_00756	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPAIPLAM_00757	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NPAIPLAM_00758	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NPAIPLAM_00759	5.75e-132	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NPAIPLAM_00760	2.95e-158	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NPAIPLAM_00761	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPAIPLAM_00762	2.92e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPAIPLAM_00763	4.22e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NPAIPLAM_00764	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPAIPLAM_00765	3.82e-23	-	-	-	-	-	-	-	-
NPAIPLAM_00766	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
NPAIPLAM_00767	8.52e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NPAIPLAM_00768	2.32e-198	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NPAIPLAM_00769	7.29e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPAIPLAM_00770	2.15e-99	yphH	-	-	S	-	-	-	Cupin domain
NPAIPLAM_00771	6.21e-241	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPAIPLAM_00772	3.61e-288	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPAIPLAM_00773	1.51e-188	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NPAIPLAM_00774	3.11e-219	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NPAIPLAM_00775	6.13e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NPAIPLAM_00776	4.38e-208	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPAIPLAM_00777	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPAIPLAM_00778	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NPAIPLAM_00779	2.66e-19	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NPAIPLAM_00780	2.5e-258	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPAIPLAM_00781	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPAIPLAM_00782	4.64e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPAIPLAM_00783	3.43e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NPAIPLAM_00784	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NPAIPLAM_00785	1.63e-146	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NPAIPLAM_00786	4.12e-50	-	-	-	-	-	-	-	-
NPAIPLAM_00787	0.0	ydaO	-	-	E	-	-	-	amino acid
NPAIPLAM_00788	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPAIPLAM_00789	5.71e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPAIPLAM_00790	3.28e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPAIPLAM_00791	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NPAIPLAM_00792	4.95e-223	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPAIPLAM_00793	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NPAIPLAM_00794	1.09e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NPAIPLAM_00795	5.43e-181	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
NPAIPLAM_00796	2.25e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPAIPLAM_00797	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NPAIPLAM_00798	2.29e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPAIPLAM_00799	3.46e-94	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPAIPLAM_00800	1.32e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPAIPLAM_00801	2.67e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NPAIPLAM_00802	1.86e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NPAIPLAM_00803	6.95e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPAIPLAM_00804	2.18e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPAIPLAM_00805	8.9e-96	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NPAIPLAM_00806	3.15e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPAIPLAM_00808	2.87e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPAIPLAM_00809	1.53e-140	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
NPAIPLAM_00810	3.25e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NPAIPLAM_00811	3.25e-274	arcT	-	-	E	-	-	-	Aminotransferase
NPAIPLAM_00812	1.23e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NPAIPLAM_00813	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NPAIPLAM_00814	1.91e-302	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
NPAIPLAM_00815	4.08e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
NPAIPLAM_00816	1.71e-238	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPAIPLAM_00817	5.91e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
NPAIPLAM_00818	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NPAIPLAM_00819	1.53e-217	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NPAIPLAM_00820	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NPAIPLAM_00821	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NPAIPLAM_00822	1.52e-187	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NPAIPLAM_00823	4.69e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPAIPLAM_00824	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NPAIPLAM_00825	6.77e-247	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPAIPLAM_00826	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
NPAIPLAM_00827	9.81e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPAIPLAM_00828	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NPAIPLAM_00829	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPAIPLAM_00830	5.65e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPAIPLAM_00831	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPAIPLAM_00833	3.69e-113	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPAIPLAM_00834	6.56e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NPAIPLAM_00835	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPAIPLAM_00836	1.04e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPAIPLAM_00837	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NPAIPLAM_00838	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NPAIPLAM_00839	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NPAIPLAM_00840	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NPAIPLAM_00841	9.83e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NPAIPLAM_00842	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NPAIPLAM_00843	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPAIPLAM_00844	3.88e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPAIPLAM_00845	3.67e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NPAIPLAM_00846	1.96e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPAIPLAM_00847	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPAIPLAM_00848	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NPAIPLAM_00849	2.48e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPAIPLAM_00850	2.04e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NPAIPLAM_00851	7.6e-133	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
NPAIPLAM_00852	6.81e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPAIPLAM_00853	2.07e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPAIPLAM_00854	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NPAIPLAM_00855	9.63e-130	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NPAIPLAM_00856	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPAIPLAM_00857	1.36e-264	yacL	-	-	S	-	-	-	domain protein
NPAIPLAM_00858	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPAIPLAM_00859	1.97e-124	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
NPAIPLAM_00860	6.29e-71	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NPAIPLAM_00861	1.44e-157	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPAIPLAM_00862	1.46e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
NPAIPLAM_00863	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NPAIPLAM_00864	1.21e-210	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPAIPLAM_00865	3.86e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPAIPLAM_00866	1.77e-212	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
NPAIPLAM_00867	3.2e-241	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
NPAIPLAM_00868	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NPAIPLAM_00870	1.71e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NPAIPLAM_00871	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
NPAIPLAM_00872	4.49e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPAIPLAM_00873	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPAIPLAM_00874	1.44e-164	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NPAIPLAM_00875	7.44e-169	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NPAIPLAM_00876	1.44e-143	-	-	-	-	-	-	-	-
NPAIPLAM_00879	1.79e-207	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPAIPLAM_00880	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NPAIPLAM_00881	1.79e-217	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
NPAIPLAM_00882	3.1e-214	-	-	-	G	-	-	-	Phosphotransferase enzyme family
NPAIPLAM_00883	2.2e-226	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
NPAIPLAM_00884	4.43e-250	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NPAIPLAM_00885	1.39e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NPAIPLAM_00886	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPAIPLAM_00887	2.6e-164	-	-	-	F	-	-	-	glutamine amidotransferase
NPAIPLAM_00888	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NPAIPLAM_00889	3.73e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NPAIPLAM_00890	3.02e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NPAIPLAM_00891	4.82e-103	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPAIPLAM_00892	3e-37	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NPAIPLAM_00893	2.98e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPAIPLAM_00894	1.85e-200	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NPAIPLAM_00895	1.03e-239	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NPAIPLAM_00896	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NPAIPLAM_00897	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPAIPLAM_00898	1.91e-261	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPAIPLAM_00899	6.66e-32	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
NPAIPLAM_00900	1.14e-146	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NPAIPLAM_00901	2.85e-144	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NPAIPLAM_00902	3.35e-170	epsB	-	-	M	-	-	-	biosynthesis protein
NPAIPLAM_00903	1.24e-217	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPAIPLAM_00904	9.48e-262	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPAIPLAM_00905	2.28e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NPAIPLAM_00906	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPAIPLAM_00907	1.47e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NPAIPLAM_00908	2.93e-186	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NPAIPLAM_00909	1.83e-206	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NPAIPLAM_00910	9.7e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NPAIPLAM_00911	2.31e-185	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
NPAIPLAM_00912	4.43e-272	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
NPAIPLAM_00913	4.91e-240	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NPAIPLAM_00914	1.25e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPAIPLAM_00915	2.56e-284	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPAIPLAM_00916	1.82e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_00917	1.22e-68	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPAIPLAM_00918	5.65e-62	-	-	-	-	-	-	-	-
NPAIPLAM_00919	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NPAIPLAM_00920	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
NPAIPLAM_00921	1.5e-194	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NPAIPLAM_00922	2.24e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPAIPLAM_00923	4.3e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPAIPLAM_00924	5.44e-278	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NPAIPLAM_00925	3.96e-312	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPAIPLAM_00926	7.63e-248	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NPAIPLAM_00927	1.88e-155	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NPAIPLAM_00928	6.53e-308	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPAIPLAM_00929	1.54e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPAIPLAM_00930	8.78e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NPAIPLAM_00931	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPAIPLAM_00932	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
NPAIPLAM_00933	7.65e-68	-	-	-	S	-	-	-	interspecies interaction between organisms
NPAIPLAM_00934	1.98e-84	-	-	-	S	-	-	-	interspecies interaction between organisms
NPAIPLAM_00935	8.64e-178	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
NPAIPLAM_00936	2.33e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NPAIPLAM_00937	9.17e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPAIPLAM_00938	8.72e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NPAIPLAM_00939	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NPAIPLAM_00940	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPAIPLAM_00941	7.88e-233	camS	-	-	S	-	-	-	sex pheromone
NPAIPLAM_00942	4.92e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPAIPLAM_00943	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPAIPLAM_00944	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPAIPLAM_00945	8.8e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NPAIPLAM_00946	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPAIPLAM_00947	3.18e-64	-	-	-	K	-	-	-	TRANSCRIPTIONal
NPAIPLAM_00948	2.72e-58	-	-	-	S	-	-	-	Fic/DOC family
NPAIPLAM_00949	1.54e-124	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
NPAIPLAM_00950	5.61e-237	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
NPAIPLAM_00951	1.94e-235	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
NPAIPLAM_00952	7.38e-274	-	-	-	E	-	-	-	Aminotransferase
NPAIPLAM_00955	1.62e-91	-	-	-	S	-	-	-	Phage minor capsid protein 2
NPAIPLAM_00956	7.21e-67	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPAIPLAM_00957	7.8e-124	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NPAIPLAM_00958	6.35e-26	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
NPAIPLAM_00959	1.51e-51	-	-	-	S	-	-	-	DUF218 domain
NPAIPLAM_00960	1.11e-78	-	-	-	S	-	-	-	DUF218 domain
NPAIPLAM_00961	1.57e-137	yvgN	-	-	C	-	-	-	Aldo keto reductase
NPAIPLAM_00962	6.64e-18	yvgN	-	-	C	-	-	-	Aldo keto reductase
NPAIPLAM_00964	1.85e-105	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NPAIPLAM_00965	6.38e-194	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NPAIPLAM_00966	3.36e-253	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
NPAIPLAM_00968	2.55e-55	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NPAIPLAM_00969	1.14e-256	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NPAIPLAM_00970	2.21e-226	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPAIPLAM_00971	2.4e-54	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPAIPLAM_00972	1.15e-144	-	-	-	S	-	-	-	membrane
NPAIPLAM_00973	5.26e-139	-	-	-	S	-	-	-	VIT family
NPAIPLAM_00974	9.74e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPAIPLAM_00975	1.18e-28	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
NPAIPLAM_00976	5.37e-283	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPAIPLAM_00977	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPAIPLAM_00978	2.24e-75	-	-	-	-	-	-	-	-
NPAIPLAM_00979	3.82e-94	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NPAIPLAM_00980	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NPAIPLAM_00981	1.16e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NPAIPLAM_00982	3.07e-184	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NPAIPLAM_00983	2.36e-214	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPAIPLAM_00985	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPAIPLAM_00986	7.04e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NPAIPLAM_00987	3.88e-241	-	-	-	I	-	-	-	Alpha beta
NPAIPLAM_00988	1.58e-212	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NPAIPLAM_00989	3.71e-236	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NPAIPLAM_00990	3.06e-203	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NPAIPLAM_00991	1.9e-256	-	-	-	-	-	-	-	-
NPAIPLAM_00992	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPAIPLAM_00993	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPAIPLAM_00995	8.11e-145	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
NPAIPLAM_00996	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NPAIPLAM_00997	9.04e-171	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPAIPLAM_00998	1.53e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NPAIPLAM_00999	4.62e-252	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NPAIPLAM_01000	2.56e-29	dltr	-	-	K	-	-	-	response regulator
NPAIPLAM_01001	4.79e-12	sptS	-	-	T	-	-	-	Histidine kinase
NPAIPLAM_01002	1.63e-119	sptS	-	-	T	-	-	-	Histidine kinase
NPAIPLAM_01003	1.61e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NPAIPLAM_01004	1.57e-129	-	-	-	K	-	-	-	acetyltransferase
NPAIPLAM_01005	4.29e-174	-	-	-	IQ	-	-	-	dehydrogenase reductase
NPAIPLAM_01006	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPAIPLAM_01007	9.14e-203	-	-	-	EG	-	-	-	EamA-like transporter family
NPAIPLAM_01008	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NPAIPLAM_01009	8.38e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NPAIPLAM_01010	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
NPAIPLAM_01011	1.69e-296	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPAIPLAM_01012	4.67e-125	-	-	-	S	-	-	-	Pfam:DUF3816
NPAIPLAM_01013	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPAIPLAM_01014	7.08e-142	pncA	-	-	Q	-	-	-	Isochorismatase family
NPAIPLAM_01015	1.68e-164	-	-	-	F	-	-	-	NUDIX domain
NPAIPLAM_01016	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NPAIPLAM_01017	2.41e-07	-	-	-	-	-	-	-	-
NPAIPLAM_01018	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NPAIPLAM_01019	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPAIPLAM_01020	2.67e-292	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NPAIPLAM_01021	1.49e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NPAIPLAM_01022	7.67e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPAIPLAM_01023	3.84e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
NPAIPLAM_01025	2.74e-151	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
NPAIPLAM_01026	2.79e-102	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NPAIPLAM_01027	7.27e-112	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
NPAIPLAM_01028	3.99e-94	-	-	-	M	-	-	-	LysM domain protein
NPAIPLAM_01029	1.86e-239	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NPAIPLAM_01030	1.85e-301	-	-	-	F	ko:K03458	-	ko00000	Permease
NPAIPLAM_01031	9.88e-205	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
NPAIPLAM_01032	4.25e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPAIPLAM_01033	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NPAIPLAM_01034	6.44e-145	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NPAIPLAM_01035	1.37e-182	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NPAIPLAM_01036	1.92e-18	ebrB	-	-	U	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
NPAIPLAM_01037	2.48e-45	dltr	-	-	K	-	-	-	DNA-binding response regulator
NPAIPLAM_01038	7.17e-184	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NPAIPLAM_01039	1.67e-45	-	-	-	S	-	-	-	Fic/DOC family
NPAIPLAM_01040	1.59e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NPAIPLAM_01041	3.01e-138	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NPAIPLAM_01042	5.43e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NPAIPLAM_01043	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
NPAIPLAM_01044	3.55e-154	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
NPAIPLAM_01045	9.08e-197	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
NPAIPLAM_01046	1.8e-26	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NPAIPLAM_01047	1.46e-64	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NPAIPLAM_01048	6.75e-22	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NPAIPLAM_01050	5.14e-306	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NPAIPLAM_01051	1.03e-49	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NPAIPLAM_01052	9.9e-177	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NPAIPLAM_01053	5.56e-131	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NPAIPLAM_01055	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
NPAIPLAM_01056	7.57e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
NPAIPLAM_01057	4.85e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
NPAIPLAM_01058	5.48e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NPAIPLAM_01059	2.01e-119	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NPAIPLAM_01060	3.15e-98	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NPAIPLAM_01061	7.86e-92	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NPAIPLAM_01062	6.53e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NPAIPLAM_01063	5.96e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NPAIPLAM_01064	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPAIPLAM_01065	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPAIPLAM_01066	2.5e-132	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPAIPLAM_01067	9.3e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NPAIPLAM_01068	3.71e-197	-	-	-	D	-	-	-	DNA integration
NPAIPLAM_01069	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPAIPLAM_01070	6.25e-213	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NPAIPLAM_01071	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPAIPLAM_01072	1.78e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPAIPLAM_01073	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NPAIPLAM_01074	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NPAIPLAM_01075	6.75e-215	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NPAIPLAM_01076	9.86e-146	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
NPAIPLAM_01077	4.44e-273	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
NPAIPLAM_01078	4.49e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
NPAIPLAM_01079	1.34e-139	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NPAIPLAM_01080	2.55e-121	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPAIPLAM_01081	3.45e-240	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPAIPLAM_01082	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01083	7.24e-283	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPAIPLAM_01084	1.29e-211	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NPAIPLAM_01085	2.07e-299	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NPAIPLAM_01086	3.1e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPAIPLAM_01087	1.29e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NPAIPLAM_01088	4.63e-275	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NPAIPLAM_01089	2.29e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NPAIPLAM_01090	5.17e-50	-	-	-	M	-	-	-	Lysin motif
NPAIPLAM_01091	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NPAIPLAM_01092	5.44e-254	-	-	-	S	-	-	-	Helix-turn-helix domain
NPAIPLAM_01093	3.37e-111	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPAIPLAM_01094	1.68e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NPAIPLAM_01095	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPAIPLAM_01096	1.18e-182	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPAIPLAM_01097	2.06e-85	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPAIPLAM_01098	5.74e-173	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NPAIPLAM_01099	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NPAIPLAM_01100	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NPAIPLAM_01101	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NPAIPLAM_01103	2.52e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NPAIPLAM_01104	6.96e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPAIPLAM_01105	8.01e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NPAIPLAM_01106	5.64e-153	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
NPAIPLAM_01107	1.38e-292	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
NPAIPLAM_01108	3.01e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPAIPLAM_01109	3.27e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPAIPLAM_01110	1.49e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPAIPLAM_01111	1.42e-219	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPAIPLAM_01112	1.1e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPAIPLAM_01113	2.59e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPAIPLAM_01114	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPAIPLAM_01115	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NPAIPLAM_01116	3.39e-230	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPAIPLAM_01117	4.95e-216	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPAIPLAM_01118	2.57e-42	-	-	-	EGP	-	-	-	Major Facilitator
NPAIPLAM_01119	1.06e-83	-	-	-	EGP	-	-	-	Major Facilitator
NPAIPLAM_01121	1.15e-66	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPAIPLAM_01122	6.62e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NPAIPLAM_01123	1.5e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NPAIPLAM_01124	7.28e-138	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPAIPLAM_01125	2.25e-121	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NPAIPLAM_01126	8.33e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPAIPLAM_01127	3.04e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NPAIPLAM_01128	5.14e-68	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPAIPLAM_01129	1.09e-90	-	-	-	-	-	-	-	-
NPAIPLAM_01130	3.63e-271	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NPAIPLAM_01131	2.32e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NPAIPLAM_01132	5.22e-177	-	-	-	-	-	-	-	-
NPAIPLAM_01133	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NPAIPLAM_01134	1.94e-122	-	-	-	M	-	-	-	PFAM NLP P60 protein
NPAIPLAM_01135	5.58e-148	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
NPAIPLAM_01136	1.04e-136	-	-	-	L	-	-	-	Integrase
NPAIPLAM_01137	2.47e-87	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NPAIPLAM_01138	1.47e-134	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NPAIPLAM_01139	2.62e-08	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
NPAIPLAM_01140	7.36e-203	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NPAIPLAM_01141	1.75e-194	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NPAIPLAM_01142	7.95e-32	-	-	-	L	-	-	-	Helix-turn-helix domain
NPAIPLAM_01143	1.24e-130	-	-	-	K	-	-	-	DNA-templated transcription, initiation
NPAIPLAM_01145	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
NPAIPLAM_01146	2.81e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPAIPLAM_01147	1.01e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NPAIPLAM_01148	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NPAIPLAM_01149	4.01e-97	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NPAIPLAM_01150	1.81e-135	-	-	-	-	-	-	-	-
NPAIPLAM_01151	1.88e-274	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPAIPLAM_01152	2.8e-130	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPAIPLAM_01153	9.15e-80	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPAIPLAM_01154	7.59e-58	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPAIPLAM_01155	2.08e-127	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPAIPLAM_01156	9.54e-134	-	-	-	S	-	-	-	CAAX protease self-immunity
NPAIPLAM_01158	2.36e-195	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
NPAIPLAM_01159	7.3e-174	-	-	-	M	-	-	-	Glycosyl transferase 4-like
NPAIPLAM_01160	6.11e-106	usp5	-	-	T	-	-	-	universal stress protein
NPAIPLAM_01161	3.17e-100	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
NPAIPLAM_01162	1.04e-125	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPAIPLAM_01163	1.04e-22	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPAIPLAM_01164	4.08e-225	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NPAIPLAM_01165	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NPAIPLAM_01166	2.61e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPAIPLAM_01167	2.93e-159	-	-	-	S	-	-	-	Membrane
NPAIPLAM_01168	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NPAIPLAM_01169	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NPAIPLAM_01170	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NPAIPLAM_01171	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPAIPLAM_01172	9.18e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NPAIPLAM_01173	2.11e-248	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NPAIPLAM_01174	3.35e-215	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPAIPLAM_01175	1.57e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPAIPLAM_01176	3.03e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NPAIPLAM_01177	1.03e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
NPAIPLAM_01178	8.05e-261	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NPAIPLAM_01179	8.81e-152	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPAIPLAM_01180	1.12e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPAIPLAM_01181	8.77e-08	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
NPAIPLAM_01182	9.53e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
NPAIPLAM_01183	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NPAIPLAM_01184	7.53e-194	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NPAIPLAM_01185	3.56e-69	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
NPAIPLAM_01186	8.06e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NPAIPLAM_01187	5.51e-160	-	-	-	C	-	-	-	nitroreductase
NPAIPLAM_01188	1.01e-183	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
NPAIPLAM_01189	4.98e-237	fdrA	-	-	C	ko:K02381	-	ko00000	CoA-ligase
NPAIPLAM_01190	1.25e-25	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
NPAIPLAM_01191	1.62e-154	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPAIPLAM_01192	7.3e-60	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPAIPLAM_01193	1.11e-245	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NPAIPLAM_01194	6.53e-131	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
NPAIPLAM_01195	1.62e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01196	2.98e-137	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPAIPLAM_01197	2.72e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
NPAIPLAM_01198	9.93e-99	ywnA	-	-	K	-	-	-	Transcriptional regulator
NPAIPLAM_01199	5.23e-97	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
NPAIPLAM_01200	3.5e-55	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NPAIPLAM_01201	2.5e-13	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NPAIPLAM_01202	2.98e-28	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
NPAIPLAM_01203	2.53e-109	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NPAIPLAM_01204	1.52e-108	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NPAIPLAM_01205	6.52e-163	XK27_08315	-	-	M	-	-	-	Sulfatase
NPAIPLAM_01206	2.34e-16	XK27_08315	-	-	M	-	-	-	Sulfatase
NPAIPLAM_01207	5.86e-192	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NPAIPLAM_01208	2.53e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
NPAIPLAM_01210	2.05e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NPAIPLAM_01211	2.86e-151	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
NPAIPLAM_01212	1.06e-185	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NPAIPLAM_01213	1.35e-116	cps3F	-	-	-	-	-	-	-
NPAIPLAM_01214	4.27e-38	-	-	-	M	-	-	-	biosynthesis protein
NPAIPLAM_01215	7.07e-65	cps3I	-	-	G	-	-	-	Acyltransferase family
NPAIPLAM_01216	5.66e-280	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NPAIPLAM_01217	2.67e-254	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NPAIPLAM_01218	3.84e-26	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
NPAIPLAM_01219	5.56e-19	-	-	-	NU	-	-	-	mannosyl-glycoprotein
NPAIPLAM_01220	2.33e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NPAIPLAM_01221	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
NPAIPLAM_01222	4.35e-108	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NPAIPLAM_01223	1.76e-90	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NPAIPLAM_01224	1.8e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
NPAIPLAM_01225	1.42e-244	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
NPAIPLAM_01226	1.59e-86	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPAIPLAM_01227	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NPAIPLAM_01228	3.52e-173	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
NPAIPLAM_01229	4.96e-271	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
NPAIPLAM_01230	4.87e-253	-	-	-	EGP	-	-	-	Major Facilitator
NPAIPLAM_01231	4.1e-153	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPAIPLAM_01232	2.41e-199	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NPAIPLAM_01233	1.58e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NPAIPLAM_01234	2.45e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
NPAIPLAM_01235	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
NPAIPLAM_01236	1.27e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPAIPLAM_01237	2.12e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPAIPLAM_01238	2.43e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NPAIPLAM_01239	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPAIPLAM_01240	1.03e-153	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
NPAIPLAM_01241	7.13e-108	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
NPAIPLAM_01242	1.18e-229	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NPAIPLAM_01243	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NPAIPLAM_01244	1.71e-284	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPAIPLAM_01245	7.74e-231	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NPAIPLAM_01246	2.04e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPAIPLAM_01247	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NPAIPLAM_01248	1.21e-48	-	-	-	-	-	-	-	-
NPAIPLAM_01249	4.14e-174	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01250	4.27e-155	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPAIPLAM_01251	4.43e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NPAIPLAM_01252	9.08e-71	-	-	-	-	-	-	-	-
NPAIPLAM_01253	2.01e-215	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPAIPLAM_01254	1.66e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPAIPLAM_01255	1.46e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NPAIPLAM_01256	9.55e-118	ymdB	-	-	S	-	-	-	Macro domain protein
NPAIPLAM_01257	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NPAIPLAM_01258	1.73e-290	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NPAIPLAM_01259	9.94e-60	-	-	-	-	-	-	-	-
NPAIPLAM_01260	4.33e-271	-	-	-	S	-	-	-	Putative metallopeptidase domain
NPAIPLAM_01261	1.41e-263	-	-	-	S	-	-	-	associated with various cellular activities
NPAIPLAM_01262	3.31e-149	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NPAIPLAM_01263	9.99e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NPAIPLAM_01265	2.32e-161	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
NPAIPLAM_01266	4.34e-73	-	-	-	-	-	-	-	-
NPAIPLAM_01267	3.04e-140	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NPAIPLAM_01268	6.55e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPAIPLAM_01269	1.68e-138	-	-	-	-	-	-	-	-
NPAIPLAM_01270	1.11e-35	-	-	-	-	-	-	-	-
NPAIPLAM_01271	1.11e-95	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPAIPLAM_01272	1.46e-104	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPAIPLAM_01273	7.02e-309	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPAIPLAM_01274	1.69e-59	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NPAIPLAM_01275	3.57e-98	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NPAIPLAM_01276	2.78e-156	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01277	3.17e-206	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NPAIPLAM_01278	1.58e-138	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPAIPLAM_01279	1.77e-88	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
NPAIPLAM_01280	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NPAIPLAM_01281	1.56e-62	-	-	-	-	-	-	-	-
NPAIPLAM_01282	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPAIPLAM_01283	1.94e-109	-	-	-	L	-	-	-	nuclease
NPAIPLAM_01284	4.9e-206	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NPAIPLAM_01285	5.53e-145	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NPAIPLAM_01286	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPAIPLAM_01287	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPAIPLAM_01288	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NPAIPLAM_01289	1.25e-283	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NPAIPLAM_01290	5e-17	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
NPAIPLAM_01291	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPAIPLAM_01292	6.31e-26	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
NPAIPLAM_01293	3e-223	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPAIPLAM_01294	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
NPAIPLAM_01295	4.05e-242	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NPAIPLAM_01296	0.0	potE	-	-	E	-	-	-	Amino Acid
NPAIPLAM_01297	3.44e-139	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NPAIPLAM_01299	3.01e-130	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
NPAIPLAM_01300	1.28e-226	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NPAIPLAM_01301	3.38e-209	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NPAIPLAM_01302	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
NPAIPLAM_01307	3.57e-202	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NPAIPLAM_01308	3.2e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPAIPLAM_01309	6.43e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPAIPLAM_01310	9.43e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NPAIPLAM_01311	4.13e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPAIPLAM_01312	2.65e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NPAIPLAM_01313	8.3e-142	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
NPAIPLAM_01314	8.41e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NPAIPLAM_01315	1.26e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NPAIPLAM_01316	1.36e-161	-	-	-	S	-	-	-	Putative threonine/serine exporter
NPAIPLAM_01317	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NPAIPLAM_01318	1.81e-148	-	-	-	I	-	-	-	phosphatase
NPAIPLAM_01319	2.43e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPAIPLAM_01321	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NPAIPLAM_01322	4.69e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NPAIPLAM_01328	5.16e-15	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPAIPLAM_01329	5.36e-24	-	-	-	IQ	-	-	-	reductase
NPAIPLAM_01330	1.07e-41	-	-	-	IQ	-	-	-	reductase
NPAIPLAM_01331	8.33e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NPAIPLAM_01332	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NPAIPLAM_01333	3.84e-121	-	-	-	V	-	-	-	VanZ like family
NPAIPLAM_01334	5.71e-282	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NPAIPLAM_01335	2.1e-45	-	-	-	-	-	-	-	-
NPAIPLAM_01336	2.69e-231	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPAIPLAM_01337	2.34e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
NPAIPLAM_01338	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NPAIPLAM_01339	4.57e-217	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
NPAIPLAM_01340	3.25e-267	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
NPAIPLAM_01341	3.13e-21	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
NPAIPLAM_01342	2.86e-120	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
NPAIPLAM_01343	3.95e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NPAIPLAM_01344	1.66e-215	-	-	-	-	-	-	-	-
NPAIPLAM_01345	4.69e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
NPAIPLAM_01346	8.51e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NPAIPLAM_01347	1.36e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
NPAIPLAM_01348	3.01e-93	-	-	-	F	-	-	-	Nudix hydrolase
NPAIPLAM_01349	8.49e-262	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NPAIPLAM_01350	2.75e-244	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NPAIPLAM_01351	1.3e-254	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01352	3.17e-125	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01353	1.02e-102	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
NPAIPLAM_01354	4.15e-14	-	-	-	-	-	-	-	-
NPAIPLAM_01356	1.09e-74	-	-	-	-	-	-	-	-
NPAIPLAM_01358	1.23e-166	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
NPAIPLAM_01359	6.37e-185	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPAIPLAM_01360	1.3e-205	yvgN	-	-	S	-	-	-	Aldo keto reductase
NPAIPLAM_01361	1.17e-154	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NPAIPLAM_01362	1.88e-106	-	-	-	K	-	-	-	GNAT family
NPAIPLAM_01364	7.41e-84	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NPAIPLAM_01365	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NPAIPLAM_01366	4.14e-202	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NPAIPLAM_01367	1e-131	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NPAIPLAM_01368	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NPAIPLAM_01369	4.06e-243	mocA	-	-	S	-	-	-	Oxidoreductase
NPAIPLAM_01370	5.52e-303	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NPAIPLAM_01372	4.61e-97	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
NPAIPLAM_01373	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NPAIPLAM_01374	7.91e-213	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NPAIPLAM_01375	2.67e-77	XK27_08315	-	-	M	-	-	-	Sulfatase
NPAIPLAM_01376	6.72e-266	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
NPAIPLAM_01377	1.09e-248	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NPAIPLAM_01378	3.36e-61	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
NPAIPLAM_01379	4.18e-207	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
NPAIPLAM_01380	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
NPAIPLAM_01381	0.0	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NPAIPLAM_01382	1.83e-186	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NPAIPLAM_01383	1.42e-197	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
NPAIPLAM_01384	5.9e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
NPAIPLAM_01385	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NPAIPLAM_01386	2.92e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01387	2.97e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NPAIPLAM_01388	4.75e-145	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NPAIPLAM_01389	1.55e-73	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
NPAIPLAM_01390	4.63e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NPAIPLAM_01391	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
NPAIPLAM_01400	1.35e-117	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
NPAIPLAM_01401	4.31e-191	-	-	-	L	-	-	-	DNA replication protein
NPAIPLAM_01407	1.53e-22	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NPAIPLAM_01408	2.64e-286	-	-	-	P	-	-	-	Chloride transporter, ClC family
NPAIPLAM_01409	3.92e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NPAIPLAM_01410	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPAIPLAM_01411	1.29e-118	cvpA	-	-	S	-	-	-	Colicin V production protein
NPAIPLAM_01412	3.2e-211	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPAIPLAM_01413	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NPAIPLAM_01414	1e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPAIPLAM_01415	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NPAIPLAM_01416	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPAIPLAM_01417	6.93e-300	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPAIPLAM_01418	2.8e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NPAIPLAM_01419	1.11e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NPAIPLAM_01420	2.09e-224	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
NPAIPLAM_01421	3.61e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPAIPLAM_01422	1.77e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPAIPLAM_01423	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPAIPLAM_01424	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPAIPLAM_01425	2.52e-302	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NPAIPLAM_01426	7.88e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPAIPLAM_01427	6.58e-293	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NPAIPLAM_01428	1.79e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPAIPLAM_01429	6.15e-146	-	-	-	S	-	-	-	Helix-turn-helix domain
NPAIPLAM_01430	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
NPAIPLAM_01431	9.45e-298	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NPAIPLAM_01432	3.88e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NPAIPLAM_01433	5.45e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01434	3.81e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NPAIPLAM_01435	9.04e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NPAIPLAM_01436	1.95e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NPAIPLAM_01437	1.56e-231	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NPAIPLAM_01438	5.3e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NPAIPLAM_01439	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NPAIPLAM_01440	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPAIPLAM_01441	6.28e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPAIPLAM_01443	8.64e-96	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NPAIPLAM_01444	2.08e-211	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives, IS30 family
NPAIPLAM_01445	4.86e-14	citR	-	-	K	-	-	-	Transcriptional regulator, contains sigma factor-related N-terminal domain
NPAIPLAM_01446	3.99e-259	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
NPAIPLAM_01447	2.81e-283	citP	-	-	C	-	-	-	Na citrate symporter
NPAIPLAM_01448	3.15e-09	-	-	-	-	-	-	-	-
NPAIPLAM_01449	4.78e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NPAIPLAM_01450	7.84e-71	-	-	-	K	-	-	-	Helix-turn-helix domain
NPAIPLAM_01451	7.21e-15	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
NPAIPLAM_01452	7.76e-41	-	-	-	K	-	-	-	Transcriptional regulator
NPAIPLAM_01453	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPAIPLAM_01454	1.96e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NPAIPLAM_01455	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NPAIPLAM_01456	6.57e-40	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
NPAIPLAM_01457	2.16e-201	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
NPAIPLAM_01458	9.92e-10	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPAIPLAM_01459	7.14e-105	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPAIPLAM_01460	2.3e-23	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
NPAIPLAM_01461	5.95e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPAIPLAM_01462	5.85e-169	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPAIPLAM_01463	2.3e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPAIPLAM_01464	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NPAIPLAM_01465	2.91e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPAIPLAM_01466	2.31e-211	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPAIPLAM_01467	1.58e-122	-	-	-	K	-	-	-	transcriptional regulator
NPAIPLAM_01468	2.12e-70	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPAIPLAM_01469	1e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPAIPLAM_01470	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPAIPLAM_01471	6.33e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NPAIPLAM_01472	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
NPAIPLAM_01473	4.12e-164	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
NPAIPLAM_01474	1.73e-217	-	-	-	GK	-	-	-	ROK family
NPAIPLAM_01475	3.92e-55	-	-	-	-	-	-	-	-
NPAIPLAM_01476	9.88e-105	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NPAIPLAM_01478	3.46e-74	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPAIPLAM_01479	3.16e-78	-	-	-	S	-	-	-	branched-chain amino acid
NPAIPLAM_01480	2.3e-175	-	-	-	E	-	-	-	AzlC protein
NPAIPLAM_01481	6.96e-262	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPAIPLAM_01482	4.21e-265	hpk31	-	-	T	-	-	-	Histidine kinase
NPAIPLAM_01483	2.05e-156	vanR	-	-	K	-	-	-	response regulator
NPAIPLAM_01484	8.21e-121	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
NPAIPLAM_01485	2.29e-38	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
NPAIPLAM_01486	1.23e-96	-	-	-	L	ko:K07497	-	ko00000	Transposase and inactivated derivatives
NPAIPLAM_01487	6.47e-156	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
NPAIPLAM_01489	6.1e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NPAIPLAM_01490	1.29e-31	-	-	-	D	ko:K19158	-	ko00000,ko01000,ko02048	mRNA cleavage
NPAIPLAM_01491	1.6e-19	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
NPAIPLAM_01492	2.06e-63	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPAIPLAM_01493	1.12e-34	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NPAIPLAM_01494	5.92e-157	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NPAIPLAM_01495	2.54e-147	-	-	-	Q	-	-	-	Methyltransferase domain
NPAIPLAM_01496	3.91e-111	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
NPAIPLAM_01497	2.05e-64	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
NPAIPLAM_01498	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
NPAIPLAM_01499	2.94e-111	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NPAIPLAM_01500	1.87e-95	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
NPAIPLAM_01502	7.96e-243	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NPAIPLAM_01503	5.42e-54	-	-	-	S	-	-	-	hydrolase
NPAIPLAM_01504	7.83e-109	-	-	-	S	-	-	-	hydrolase
NPAIPLAM_01505	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
NPAIPLAM_01506	1.01e-36	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01507	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NPAIPLAM_01508	4.13e-295	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NPAIPLAM_01509	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
NPAIPLAM_01510	7.91e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NPAIPLAM_01511	3.05e-192	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NPAIPLAM_01513	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPAIPLAM_01514	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
NPAIPLAM_01515	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPAIPLAM_01516	2.78e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPAIPLAM_01517	1.17e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPAIPLAM_01518	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NPAIPLAM_01519	2.33e-222	ydbI	-	-	K	-	-	-	AI-2E family transporter
NPAIPLAM_01520	3.56e-06	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPAIPLAM_01521	4.67e-61	-	-	-	L	-	-	-	MULE transposase domain
NPAIPLAM_01522	6.7e-81	-	-	-	-	-	-	-	-
NPAIPLAM_01523	1.35e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPAIPLAM_01524	4.84e-87	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPAIPLAM_01525	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NPAIPLAM_01526	2.45e-267	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPAIPLAM_01527	1.29e-177	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NPAIPLAM_01528	5.3e-201	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NPAIPLAM_01529	2.64e-267	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NPAIPLAM_01531	2.14e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NPAIPLAM_01532	1.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPAIPLAM_01533	3.24e-147	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
NPAIPLAM_01534	1.88e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
NPAIPLAM_01536	1.8e-52	-	-	-	S	-	-	-	MmgE/PrpD family
NPAIPLAM_01537	2.91e-192	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
NPAIPLAM_01538	8.5e-185	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
NPAIPLAM_01539	1.49e-115	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NPAIPLAM_01540	4.03e-75	yxeN	-	-	U	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
NPAIPLAM_01541	1.19e-58	yxeL	-	-	K	-	-	-	acetyltransferase
NPAIPLAM_01542	7.47e-78	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NPAIPLAM_01543	7.62e-270	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
NPAIPLAM_01544	7.73e-277	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NPAIPLAM_01545	3.96e-106	-	-	-	K	-	-	-	Transcriptional regulator
NPAIPLAM_01546	6.29e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPAIPLAM_01547	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPAIPLAM_01548	1.72e-75	-	-	-	-	-	-	-	-
NPAIPLAM_01549	6.09e-174	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NPAIPLAM_01550	1.8e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NPAIPLAM_01551	4.82e-72	-	-	-	-	-	-	-	-
NPAIPLAM_01553	5.81e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NPAIPLAM_01554	6.18e-122	-	-	-	S	-	-	-	integral membrane protein
NPAIPLAM_01555	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPAIPLAM_01556	3.52e-179	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NPAIPLAM_01557	3.52e-178	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NPAIPLAM_01558	9.17e-132	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NPAIPLAM_01559	2.77e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NPAIPLAM_01560	6.23e-92	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NPAIPLAM_01561	5.84e-269	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NPAIPLAM_01562	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
NPAIPLAM_01563	2.53e-241	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
NPAIPLAM_01564	1.73e-95	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
NPAIPLAM_01567	4.53e-127	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPAIPLAM_01568	2.95e-202	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NPAIPLAM_01569	1.45e-135	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPAIPLAM_01570	1.81e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NPAIPLAM_01571	1.18e-127	cadD	-	-	P	-	-	-	Cadmium resistance transporter
NPAIPLAM_01572	2.64e-53	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPAIPLAM_01574	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
NPAIPLAM_01575	1.42e-20	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
NPAIPLAM_01577	3.16e-232	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPAIPLAM_01578	9.97e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
NPAIPLAM_01579	3.55e-123	-	-	-	-	-	-	-	-
NPAIPLAM_01581	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NPAIPLAM_01582	1.63e-76	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPAIPLAM_01583	9.96e-22	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
NPAIPLAM_01584	3.91e-76	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NPAIPLAM_01585	2.98e-227	-	-	-	K	-	-	-	WYL domain
NPAIPLAM_01586	2.68e-87	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
NPAIPLAM_01587	3.57e-14	-	-	-	-	-	-	-	-
NPAIPLAM_01589	6.5e-85	-	-	-	-	-	-	-	-
NPAIPLAM_01590	1.58e-141	yicL	-	-	EG	-	-	-	EamA-like transporter family
NPAIPLAM_01591	1.68e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
NPAIPLAM_01593	4.66e-123	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
NPAIPLAM_01594	1.2e-107	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPAIPLAM_01595	3.24e-83	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPAIPLAM_01596	2.58e-184	-	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPAIPLAM_01597	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
NPAIPLAM_01598	3.64e-217	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
NPAIPLAM_01599	5.43e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NPAIPLAM_01600	1.65e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NPAIPLAM_01601	1.93e-213	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NPAIPLAM_01602	6.51e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NPAIPLAM_01603	1.7e-261	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NPAIPLAM_01604	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NPAIPLAM_01605	1.39e-28	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
NPAIPLAM_01606	2.42e-125	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NPAIPLAM_01607	1.18e-119	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NPAIPLAM_01608	9.71e-103	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NPAIPLAM_01609	2.15e-11	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NPAIPLAM_01610	1.1e-88	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NPAIPLAM_01611	4.55e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NPAIPLAM_01612	2.63e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
NPAIPLAM_01613	1.56e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NPAIPLAM_01614	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPAIPLAM_01615	1.8e-133	dar	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
NPAIPLAM_01616	4.13e-104	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPAIPLAM_01617	5.01e-164	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NPAIPLAM_01618	2.31e-120	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPAIPLAM_01619	3.41e-167	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPAIPLAM_01620	1.3e-63	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain
NPAIPLAM_01621	1.88e-190	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
NPAIPLAM_01622	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
NPAIPLAM_01623	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPAIPLAM_01624	4.34e-109	-	-	-	-	-	-	-	-
NPAIPLAM_01625	9.13e-56	-	-	-	-	-	-	-	-
NPAIPLAM_01626	3.51e-55	-	-	-	M	-	-	-	Domain of unknown function (DUF1919)
NPAIPLAM_01627	2.42e-98	-	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPAIPLAM_01628	3.89e-43	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NPAIPLAM_01629	5.55e-46	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NPAIPLAM_01630	4.04e-67	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
NPAIPLAM_01631	5.61e-66	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
NPAIPLAM_01632	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
NPAIPLAM_01633	1.21e-113	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
NPAIPLAM_01634	3e-147	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NPAIPLAM_01635	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NPAIPLAM_01636	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NPAIPLAM_01637	6.57e-223	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPAIPLAM_01638	2.92e-92	ywnA	-	-	K	-	-	-	Transcriptional regulator
NPAIPLAM_01639	1.67e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPAIPLAM_01640	7.43e-257	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NPAIPLAM_01641	4.51e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NPAIPLAM_01642	5.62e-183	yycI	-	-	S	-	-	-	YycH protein
NPAIPLAM_01643	1.65e-302	yycH	-	-	S	-	-	-	YycH protein
NPAIPLAM_01644	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPAIPLAM_01645	1.75e-166	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NPAIPLAM_01648	1.22e-78	-	-	-	-	-	-	-	-
NPAIPLAM_01649	2.54e-267	-	-	-	E	-	-	-	Major Facilitator Superfamily
NPAIPLAM_01650	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NPAIPLAM_01651	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NPAIPLAM_01652	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NPAIPLAM_01653	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPAIPLAM_01654	9.82e-151	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPAIPLAM_01655	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NPAIPLAM_01656	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPAIPLAM_01657	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPAIPLAM_01658	1.06e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPAIPLAM_01659	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
NPAIPLAM_01660	3.06e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPAIPLAM_01661	3.8e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPAIPLAM_01663	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NPAIPLAM_01664	5.32e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPAIPLAM_01665	1.43e-186	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPAIPLAM_01666	1.69e-184	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NPAIPLAM_01667	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPAIPLAM_01668	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPAIPLAM_01669	1.46e-75	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPAIPLAM_01670	1.98e-280	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NPAIPLAM_01671	1.7e-154	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NPAIPLAM_01673	1.25e-143	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
NPAIPLAM_01674	2.9e-135	-	-	-	C	-	-	-	aldo keto reductase
NPAIPLAM_01675	4.65e-255	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NPAIPLAM_01676	1.03e-282	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPAIPLAM_01677	8.86e-194	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NPAIPLAM_01678	1.16e-108	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
NPAIPLAM_01679	4.71e-148	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
NPAIPLAM_01680	1.94e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NPAIPLAM_01681	1.85e-207	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
NPAIPLAM_01682	3.98e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPAIPLAM_01684	5.57e-103	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NPAIPLAM_01685	1.03e-270	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NPAIPLAM_01687	1.09e-181	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
NPAIPLAM_01688	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NPAIPLAM_01689	6.36e-144	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NPAIPLAM_01690	1.18e-257	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NPAIPLAM_01691	3.62e-90	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NPAIPLAM_01692	6.85e-33	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NPAIPLAM_01693	0.0	-	-	-	E	-	-	-	amino acid
NPAIPLAM_01694	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPAIPLAM_01695	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPAIPLAM_01696	4.32e-65	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NPAIPLAM_01697	6.52e-114	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NPAIPLAM_01698	1.89e-81	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NPAIPLAM_01699	2.49e-276	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
NPAIPLAM_01700	8.39e-196	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, C-terminal domain
NPAIPLAM_01701	8.7e-297	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPAIPLAM_01703	5.32e-142	-	-	-	-	-	-	-	-
NPAIPLAM_01704	2.72e-212	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
NPAIPLAM_01705	1.71e-211	-	-	-	K	-	-	-	LysR substrate binding domain
NPAIPLAM_01706	1.33e-25	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NPAIPLAM_01707	3.44e-103	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPAIPLAM_01709	1.34e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
NPAIPLAM_01710	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
NPAIPLAM_01711	1.25e-206	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
NPAIPLAM_01712	2.84e-142	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NPAIPLAM_01713	7.93e-248	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
NPAIPLAM_01714	6.46e-121	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NPAIPLAM_01715	1.2e-295	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
NPAIPLAM_01717	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NPAIPLAM_01718	7.17e-64	-	-	-	-	-	-	-	-
NPAIPLAM_01719	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NPAIPLAM_01721	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPAIPLAM_01722	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NPAIPLAM_01723	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NPAIPLAM_01724	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPAIPLAM_01725	2.82e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPAIPLAM_01726	1.77e-299	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPAIPLAM_01727	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPAIPLAM_01728	5.12e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NPAIPLAM_01729	3.85e-202	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
NPAIPLAM_01730	1.81e-182	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NPAIPLAM_01731	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
NPAIPLAM_01732	1.21e-269	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
NPAIPLAM_01733	3.16e-21	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
NPAIPLAM_01734	5.61e-63	lysR	-	-	K	-	-	-	Transcriptional regulator
NPAIPLAM_01735	4.68e-21	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
NPAIPLAM_01736	6.07e-275	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NPAIPLAM_01737	2.37e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NPAIPLAM_01738	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NPAIPLAM_01739	2.54e-274	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPAIPLAM_01740	1.05e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NPAIPLAM_01741	1.99e-231	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NPAIPLAM_01742	5.53e-20	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
NPAIPLAM_01743	2.61e-70	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
NPAIPLAM_01744	1.25e-96	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
NPAIPLAM_01745	3.8e-27	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
NPAIPLAM_01746	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NPAIPLAM_01747	9.37e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NPAIPLAM_01748	9.87e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPAIPLAM_01749	2.42e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPAIPLAM_01750	1.76e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
NPAIPLAM_01751	8.38e-152	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPAIPLAM_01752	1.55e-170	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NPAIPLAM_01753	9.35e-128	-	-	-	-	-	-	-	-
NPAIPLAM_01754	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
NPAIPLAM_01756	0.0	copB	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NPAIPLAM_01757	1.49e-97	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
NPAIPLAM_01758	1.6e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NPAIPLAM_01759	8.23e-215	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NPAIPLAM_01760	9.65e-181	yceF	-	-	P	ko:K05794	-	ko00000	membrane
NPAIPLAM_01761	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NPAIPLAM_01762	7.24e-121	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
NPAIPLAM_01763	6e-201	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
NPAIPLAM_01764	7.07e-187	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NPAIPLAM_01765	1.75e-194	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NPAIPLAM_01767	3.03e-181	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NPAIPLAM_01769	5.11e-76	-	-	-	K	-	-	-	Transcriptional regulator
NPAIPLAM_01770	9.9e-33	-	-	-	K	-	-	-	transcriptional regulator
NPAIPLAM_01771	2.87e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NPAIPLAM_01772	3.14e-129	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
NPAIPLAM_01773	1.12e-166	-	-	-	F	-	-	-	NUDIX domain
NPAIPLAM_01774	2.71e-95	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPAIPLAM_01775	7.5e-191	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPAIPLAM_01776	1.35e-134	pncA	-	-	Q	-	-	-	Isochorismatase family
NPAIPLAM_01777	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
NPAIPLAM_01778	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
NPAIPLAM_01779	0.0	potE	-	-	E	-	-	-	Amino Acid
NPAIPLAM_01780	1.87e-217	-	-	-	V	-	-	-	Beta-lactamase enzyme family
NPAIPLAM_01783	3.91e-31	-	-	-	-	-	-	-	-
NPAIPLAM_01784	3.7e-313	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPAIPLAM_01785	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
NPAIPLAM_01786	2.92e-14	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
NPAIPLAM_01787	2.01e-26	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
NPAIPLAM_01788	2.34e-315	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NPAIPLAM_01789	4.16e-233	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NPAIPLAM_01790	3.22e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPAIPLAM_01791	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPAIPLAM_01792	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPAIPLAM_01793	6.43e-66	ylxQ	-	-	J	-	-	-	ribosomal protein
NPAIPLAM_01794	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NPAIPLAM_01795	1.11e-281	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NPAIPLAM_01796	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NPAIPLAM_01797	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPAIPLAM_01798	2.42e-261	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPAIPLAM_01799	1.95e-248	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NPAIPLAM_01800	2.87e-263	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NPAIPLAM_01801	9.35e-173	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NPAIPLAM_01802	6.31e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
NPAIPLAM_01803	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPAIPLAM_01804	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPAIPLAM_01805	9.35e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NPAIPLAM_01806	8.21e-174	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NPAIPLAM_01807	2.22e-184	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPAIPLAM_01808	5.35e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPAIPLAM_01809	2.78e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NPAIPLAM_01810	6.85e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPAIPLAM_01811	1.28e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NPAIPLAM_01812	4.43e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
NPAIPLAM_01813	9.35e-174	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NPAIPLAM_01814	3.58e-149	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NPAIPLAM_01815	6.06e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
NPAIPLAM_01816	1.97e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
NPAIPLAM_01817	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPAIPLAM_01818	7.4e-275	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NPAIPLAM_01819	1.91e-17	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
NPAIPLAM_01820	1.24e-55	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NPAIPLAM_01821	4.98e-35	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NPAIPLAM_01822	2.07e-139	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NPAIPLAM_01823	1.77e-71	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain