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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
KHOLCCEP_00001	1.17e-202	-	-	-	S	-	-	-	Protein conserved in bacteria
KHOLCCEP_00002	8.24e-270	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KHOLCCEP_00003	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHOLCCEP_00004	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
KHOLCCEP_00005	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHOLCCEP_00006	1.29e-96	-	2.8.2.22	-	S	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
KHOLCCEP_00007	2.99e-176	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_00008	1.37e-269	-	-	-	E	-	-	-	Aminotransferase class I and II
KHOLCCEP_00009	5.43e-179	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
KHOLCCEP_00011	2.4e-136	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHOLCCEP_00012	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KHOLCCEP_00013	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KHOLCCEP_00015	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
KHOLCCEP_00016	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
KHOLCCEP_00017	1.68e-253	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
KHOLCCEP_00018	3.8e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_00019	2.44e-143	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_00020	5.91e-196	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
KHOLCCEP_00021	5.87e-180	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
KHOLCCEP_00022	6.55e-110	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
KHOLCCEP_00023	5.94e-99	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
KHOLCCEP_00024	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KHOLCCEP_00025	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
KHOLCCEP_00026	5.86e-299	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
KHOLCCEP_00030	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
KHOLCCEP_00031	2.83e-236	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
KHOLCCEP_00032	1.28e-252	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
KHOLCCEP_00033	1.23e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
KHOLCCEP_00034	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHOLCCEP_00035	5.85e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
KHOLCCEP_00036	2.53e-234	-	-	-	-	-	-	-	-
KHOLCCEP_00037	8.25e-53	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
KHOLCCEP_00038	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHOLCCEP_00039	1.49e-58	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
KHOLCCEP_00040	7.36e-106	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
KHOLCCEP_00041	1.29e-185	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHOLCCEP_00042	1.22e-251	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
KHOLCCEP_00043	6.83e-227	-	-	-	S	-	-	-	Protein of unknown function DUF58
KHOLCCEP_00044	1.78e-121	-	-	-	-	-	-	-	-
KHOLCCEP_00045	3.22e-246	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
KHOLCCEP_00046	8.15e-198	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
KHOLCCEP_00047	2.64e-116	-	-	-	-	-	-	-	-
KHOLCCEP_00049	0.0	-	-	-	S	-	-	-	PGAP1-like protein
KHOLCCEP_00050	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
KHOLCCEP_00051	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
KHOLCCEP_00052	4.7e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
KHOLCCEP_00053	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KHOLCCEP_00054	1.05e-28	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
KHOLCCEP_00055	3.29e-202	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
KHOLCCEP_00056	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
KHOLCCEP_00057	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
KHOLCCEP_00058	2.25e-178	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
KHOLCCEP_00059	1.29e-233	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHOLCCEP_00060	3.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KHOLCCEP_00061	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHOLCCEP_00062	2.25e-284	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHOLCCEP_00063	9.87e-70	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHOLCCEP_00064	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
KHOLCCEP_00065	1.44e-209	-	-	-	S	-	-	-	Protein conserved in bacteria
KHOLCCEP_00066	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KHOLCCEP_00067	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
KHOLCCEP_00068	6.97e-144	-	-	-	-	-	-	-	-
KHOLCCEP_00069	9.19e-314	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHOLCCEP_00070	1.87e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
KHOLCCEP_00071	2.19e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
KHOLCCEP_00072	2.46e-216	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
KHOLCCEP_00073	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KHOLCCEP_00074	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
KHOLCCEP_00075	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KHOLCCEP_00076	5.29e-212	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
KHOLCCEP_00077	4.8e-226	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_00078	2.74e-235	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
KHOLCCEP_00079	2.67e-56	-	-	-	-	-	-	-	-
KHOLCCEP_00080	2.1e-245	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
KHOLCCEP_00081	7.12e-254	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
KHOLCCEP_00082	1.83e-109	-	-	-	-	-	-	-	-
KHOLCCEP_00083	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
KHOLCCEP_00084	1.77e-298	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
KHOLCCEP_00085	6.73e-211	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
KHOLCCEP_00086	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
KHOLCCEP_00087	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KHOLCCEP_00088	5.17e-192	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
KHOLCCEP_00089	7.1e-144	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHOLCCEP_00090	4.82e-193	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHOLCCEP_00091	1.31e-194	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
KHOLCCEP_00092	9.73e-228	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
KHOLCCEP_00093	5.46e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHOLCCEP_00094	3.31e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
KHOLCCEP_00095	1.77e-136	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHOLCCEP_00096	1.11e-08	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
KHOLCCEP_00097	4.14e-173	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
KHOLCCEP_00098	3.39e-254	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHOLCCEP_00099	1.49e-119	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHOLCCEP_00101	5.38e-230	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHOLCCEP_00102	7.58e-248	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
KHOLCCEP_00103	3.35e-84	-	-	-	-	-	-	-	-
KHOLCCEP_00104	9.94e-149	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
KHOLCCEP_00105	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHOLCCEP_00106	7.29e-244	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
KHOLCCEP_00107	1.22e-291	-	2.6.1.33	-	M	ko:K20429	-	ko00000,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
KHOLCCEP_00108	4.4e-310	-	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp
KHOLCCEP_00109	4.19e-165	-	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
KHOLCCEP_00110	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KHOLCCEP_00111	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
KHOLCCEP_00113	7.52e-126	-	-	-	F	-	-	-	NUDIX domain
KHOLCCEP_00114	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
KHOLCCEP_00115	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KHOLCCEP_00116	7.55e-249	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_00117	5.3e-243	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_00118	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
KHOLCCEP_00119	1.8e-308	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
KHOLCCEP_00120	5.93e-196	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHOLCCEP_00121	2.39e-275	-	-	-	GK	-	-	-	ROK family
KHOLCCEP_00122	5.66e-168	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
KHOLCCEP_00123	1.4e-189	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
KHOLCCEP_00124	1.08e-81	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
KHOLCCEP_00125	1.66e-216	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
KHOLCCEP_00126	3.73e-301	-	-	-	G	-	-	-	Major Facilitator Superfamily
KHOLCCEP_00127	2.9e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHOLCCEP_00130	1.24e-233	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
KHOLCCEP_00131	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
KHOLCCEP_00132	3.15e-276	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHOLCCEP_00133	1.29e-296	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
KHOLCCEP_00134	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHOLCCEP_00135	8.76e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHOLCCEP_00136	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHOLCCEP_00137	2.48e-231	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHOLCCEP_00138	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
KHOLCCEP_00139	9.33e-96	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KHOLCCEP_00140	4.09e-251	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHOLCCEP_00141	8.85e-118	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
KHOLCCEP_00142	0.0	-	-	-	L	-	-	-	DNA helicase
KHOLCCEP_00143	1.37e-291	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KHOLCCEP_00144	1.79e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHOLCCEP_00145	2.4e-65	-	-	-	M	-	-	-	Lysin motif
KHOLCCEP_00146	3.03e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHOLCCEP_00147	4.53e-212	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHOLCCEP_00148	1.96e-226	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KHOLCCEP_00149	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHOLCCEP_00150	3.25e-222	-	-	-	-	-	-	-	-
KHOLCCEP_00151	1.7e-155	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
KHOLCCEP_00152	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
KHOLCCEP_00153	1.03e-242	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KHOLCCEP_00154	2.91e-173	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
KHOLCCEP_00155	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KHOLCCEP_00156	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
KHOLCCEP_00157	8.32e-168	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
KHOLCCEP_00158	3.31e-157	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHOLCCEP_00159	8.75e-150	-	-	-	-	-	-	-	-
KHOLCCEP_00160	1.08e-145	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
KHOLCCEP_00161	1.85e-285	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHOLCCEP_00162	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHOLCCEP_00163	1.55e-231	-	-	-	S	-	-	-	Protein conserved in bacteria
KHOLCCEP_00166	6.13e-100	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
KHOLCCEP_00167	4.09e-221	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
KHOLCCEP_00168	1.35e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
KHOLCCEP_00169	2.5e-258	-	-	-	K	-	-	-	WYL domain
KHOLCCEP_00171	0.000175	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHOLCCEP_00172	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
KHOLCCEP_00173	1.9e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
KHOLCCEP_00174	1.99e-144	-	-	-	S	-	-	-	zinc-ribbon domain
KHOLCCEP_00175	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
KHOLCCEP_00176	1.11e-53	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
KHOLCCEP_00177	1.32e-23	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
KHOLCCEP_00178	3.9e-244	-	-	-	S	-	-	-	Domain of unknown function (DUF1963)
KHOLCCEP_00179	2.53e-198	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHOLCCEP_00180	1.23e-183	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
KHOLCCEP_00181	0.0	-	-	-	I	-	-	-	acetylesterase activity
KHOLCCEP_00182	9.79e-299	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KHOLCCEP_00183	8.77e-282	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KHOLCCEP_00184	3.67e-309	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
KHOLCCEP_00186	2.73e-105	-	-	-	-	-	-	-	-
KHOLCCEP_00187	1.29e-186	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
KHOLCCEP_00188	1.38e-103	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KHOLCCEP_00189	2.15e-284	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
KHOLCCEP_00190	4.29e-203	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
KHOLCCEP_00191	1.49e-308	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
KHOLCCEP_00192	5.51e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHOLCCEP_00193	3.72e-220	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
KHOLCCEP_00194	1.25e-82	-	-	-	-	-	-	-	-
KHOLCCEP_00196	1.89e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KHOLCCEP_00197	1.32e-147	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHOLCCEP_00198	1.65e-191	-	-	-	V	-	-	-	DivIVA protein
KHOLCCEP_00199	1.92e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
KHOLCCEP_00200	9.4e-105	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHOLCCEP_00201	5.66e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHOLCCEP_00202	6.67e-314	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHOLCCEP_00203	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
KHOLCCEP_00204	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
KHOLCCEP_00205	5.02e-202	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KHOLCCEP_00206	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KHOLCCEP_00207	1.62e-110	-	-	-	-	-	-	-	-
KHOLCCEP_00208	3.43e-291	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
KHOLCCEP_00209	1.71e-209	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KHOLCCEP_00210	1.52e-81	-	-	-	S	-	-	-	Thiamine-binding protein
KHOLCCEP_00211	2.78e-248	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KHOLCCEP_00212	2.24e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
KHOLCCEP_00213	4.13e-193	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
KHOLCCEP_00214	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
KHOLCCEP_00215	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KHOLCCEP_00216	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
KHOLCCEP_00217	9.31e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
KHOLCCEP_00218	2.97e-212	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
KHOLCCEP_00219	4.13e-148	-	-	-	S	-	-	-	Vitamin K epoxide reductase
KHOLCCEP_00220	1.42e-213	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
KHOLCCEP_00221	3.18e-195	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
KHOLCCEP_00222	8.81e-218	-	-	-	S	-	-	-	Patatin-like phospholipase
KHOLCCEP_00223	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
KHOLCCEP_00224	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KHOLCCEP_00225	6.07e-116	-	-	-	K	-	-	-	MarR family
KHOLCCEP_00226	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
KHOLCCEP_00227	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
KHOLCCEP_00228	7.87e-213	-	-	-	-	-	-	-	-
KHOLCCEP_00229	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
KHOLCCEP_00231	1.69e-178	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHOLCCEP_00232	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
KHOLCCEP_00233	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHOLCCEP_00234	1.47e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHOLCCEP_00235	2.56e-220	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
KHOLCCEP_00237	1.65e-234	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
KHOLCCEP_00238	0.0	-	-	-	OP	-	-	-	Sulfurtransferase TusA
KHOLCCEP_00239	8.74e-193	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
KHOLCCEP_00240	1.13e-169	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
KHOLCCEP_00241	2.21e-47	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
KHOLCCEP_00242	7.24e-124	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
KHOLCCEP_00243	7.65e-293	aspB	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
KHOLCCEP_00244	4.28e-144	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KHOLCCEP_00245	0.0	-	-	-	S	-	-	-	zinc finger
KHOLCCEP_00246	6.43e-160	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHOLCCEP_00247	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHOLCCEP_00248	0.0	vpr	-	-	O	-	-	-	Subtilase family
KHOLCCEP_00249	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
KHOLCCEP_00250	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHOLCCEP_00251	6.97e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHOLCCEP_00252	2.35e-169	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KHOLCCEP_00253	1.03e-77	-	-	-	L	-	-	-	Transposase
KHOLCCEP_00254	3.22e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
KHOLCCEP_00255	1.59e-315	-	-	-	G	-	-	-	Major Facilitator Superfamily
KHOLCCEP_00256	7.25e-206	-	-	-	K	-	-	-	-acetyltransferase
KHOLCCEP_00257	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
KHOLCCEP_00258	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
KHOLCCEP_00259	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
KHOLCCEP_00260	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
KHOLCCEP_00261	0.0	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
KHOLCCEP_00262	9.84e-297	-	-	-	S	-	-	-	Protein of unknown function DUF58
KHOLCCEP_00263	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
KHOLCCEP_00264	1.36e-210	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
KHOLCCEP_00265	2.3e-100	-	-	-	B	-	-	-	Belongs to the OprB family
KHOLCCEP_00266	1.87e-124	-	-	-	T	-	-	-	Forkhead associated domain
KHOLCCEP_00267	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHOLCCEP_00268	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHOLCCEP_00269	1.94e-144	-	-	-	-	-	-	-	-
KHOLCCEP_00270	3.15e-236	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
KHOLCCEP_00271	3.46e-43	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
KHOLCCEP_00272	3.63e-76	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	Putative cell wall binding repeat
KHOLCCEP_00273	9.1e-157	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHOLCCEP_00274	4.1e-237	-	-	-	S	-	-	-	Membrane
KHOLCCEP_00275	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
KHOLCCEP_00276	3.23e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
KHOLCCEP_00277	1.32e-308	-	-	-	EGP	-	-	-	Sugar (and other) transporter
KHOLCCEP_00278	2.4e-296	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
KHOLCCEP_00279	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
KHOLCCEP_00280	1.2e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
KHOLCCEP_00281	8.12e-287	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
KHOLCCEP_00282	1.5e-277	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
KHOLCCEP_00283	0.0	pon1	-	-	M	-	-	-	Transglycosylase
KHOLCCEP_00284	4.67e-173	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
KHOLCCEP_00285	8.97e-151	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
KHOLCCEP_00286	7e-243	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KHOLCCEP_00287	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
KHOLCCEP_00288	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
KHOLCCEP_00289	2.17e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
KHOLCCEP_00290	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
KHOLCCEP_00291	7.82e-264	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
KHOLCCEP_00292	8.11e-203	-	-	-	I	-	-	-	Alpha/beta hydrolase family
KHOLCCEP_00293	3.88e-152	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
KHOLCCEP_00294	2.57e-78	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
KHOLCCEP_00295	8.32e-229	-	-	-	S	ko:K21688	-	ko00000	G5
KHOLCCEP_00296	0.0	-	-	-	-	-	-	-	-
KHOLCCEP_00297	3.35e-56	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
KHOLCCEP_00298	7.93e-163	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
KHOLCCEP_00299	1.53e-123	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KHOLCCEP_00300	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
KHOLCCEP_00301	9.79e-296	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KHOLCCEP_00302	8.53e-158	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
KHOLCCEP_00303	5.17e-218	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
KHOLCCEP_00304	5.8e-16	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
KHOLCCEP_00305	4.86e-259	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
KHOLCCEP_00306	1.08e-298	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
KHOLCCEP_00309	3.18e-141	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KHOLCCEP_00310	2.37e-198	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KHOLCCEP_00311	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
KHOLCCEP_00312	6.43e-11	tnp3521a2	-	-	L	-	-	-	Integrase core domain
KHOLCCEP_00313	4.58e-269	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
KHOLCCEP_00314	6.64e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHOLCCEP_00315	9.49e-198	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KHOLCCEP_00316	2.33e-81	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHOLCCEP_00317	8.39e-167	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Class II Aldolase and Adducin N-terminal domain
KHOLCCEP_00318	7.35e-219	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
KHOLCCEP_00319	0.0	-	2.7.1.53	-	G	ko:K00880	ko00040,ko00053,map00040,map00053	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
KHOLCCEP_00320	1.46e-283	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
KHOLCCEP_00321	1.42e-220	-	-	-	K	-	-	-	Putative sugar-binding domain
KHOLCCEP_00323	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_00324	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_00325	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Cation transporting ATPase, C-terminus
KHOLCCEP_00326	2.62e-157	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
KHOLCCEP_00328	6.19e-263	-	-	-	-	-	-	-	-
KHOLCCEP_00330	2.09e-272	-	-	-	-	-	-	-	-
KHOLCCEP_00331	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
KHOLCCEP_00334	5.15e-224	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
KHOLCCEP_00335	1.14e-151	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHOLCCEP_00336	6.69e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KHOLCCEP_00337	2.46e-315	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHOLCCEP_00340	1.26e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
KHOLCCEP_00341	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
KHOLCCEP_00342	6.34e-179	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KHOLCCEP_00343	2.72e-34	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
KHOLCCEP_00344	2.17e-147	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
KHOLCCEP_00345	3.01e-184	-	-	-	-	-	-	-	-
KHOLCCEP_00346	4.42e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHOLCCEP_00347	1.04e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
KHOLCCEP_00348	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
KHOLCCEP_00349	8.06e-175	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
KHOLCCEP_00350	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KHOLCCEP_00351	3.4e-211	-	-	-	P	-	-	-	Cation efflux family
KHOLCCEP_00352	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHOLCCEP_00353	1.64e-283	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
KHOLCCEP_00354	5.28e-129	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
KHOLCCEP_00355	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
KHOLCCEP_00356	2.4e-80	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
KHOLCCEP_00357	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
KHOLCCEP_00358	2.27e-139	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHOLCCEP_00359	4.27e-227	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
KHOLCCEP_00360	2.33e-106	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
KHOLCCEP_00361	1.93e-139	-	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
KHOLCCEP_00363	2.66e-156	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
KHOLCCEP_00364	0.0	-	-	-	U	ko:K06956	-	ko00000	Sodium:dicarboxylate symporter family
KHOLCCEP_00365	0.0	-	-	-	-	-	-	-	-
KHOLCCEP_00367	6.78e-276	steT	-	-	E	ko:K03294	-	ko00000	amino acid
KHOLCCEP_00368	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
KHOLCCEP_00369	7.42e-41	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
KHOLCCEP_00370	2.69e-256	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
KHOLCCEP_00372	1.01e-307	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
KHOLCCEP_00373	8.3e-171	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KHOLCCEP_00374	1.65e-78	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
KHOLCCEP_00375	2.07e-71	-	-	-	L	-	-	-	RelB antitoxin
KHOLCCEP_00376	4.24e-92	-	-	-	-	-	-	-	-
KHOLCCEP_00377	6.85e-151	-	2.1.1.72	-	L	ko:K07319	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
KHOLCCEP_00378	4.26e-29	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
KHOLCCEP_00379	4.71e-241	-	-	-	L	-	-	-	Transposase
KHOLCCEP_00380	1.52e-44	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
KHOLCCEP_00381	1.35e-286	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KHOLCCEP_00382	3.39e-166	tam	2.1.1.144	-	S	ko:K00598	-	ko00000,ko01000	Methyltransferase domain
KHOLCCEP_00387	3.96e-44	-	-	-	-	-	-	-	-
KHOLCCEP_00389	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
KHOLCCEP_00390	4.07e-57	-	-	-	K	-	-	-	Transcriptional regulator
KHOLCCEP_00392	2.2e-110	-	-	-	-	-	-	-	-
KHOLCCEP_00393	2.78e-294	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
KHOLCCEP_00394	2.84e-264	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
KHOLCCEP_00395	3.05e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KHOLCCEP_00396	2.44e-168	-	-	-	M	-	-	-	Mechanosensitive ion channel
KHOLCCEP_00397	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHOLCCEP_00399	5.72e-199	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
KHOLCCEP_00400	6.42e-176	-	-	-	S	-	-	-	Domain of unknown function (DUF4854)
KHOLCCEP_00401	1.31e-270	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
KHOLCCEP_00402	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
KHOLCCEP_00403	0.0	-	-	-	M	-	-	-	domain protein
KHOLCCEP_00404	2.45e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
KHOLCCEP_00405	3.39e-188	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHOLCCEP_00406	1e-236	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KHOLCCEP_00407	7.41e-174	-	-	-	M	-	-	-	Protein of unknown function (DUF3152)
KHOLCCEP_00408	1.14e-175	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KHOLCCEP_00411	3.42e-93	-	-	-	E	-	-	-	Domain of unknown function (DUF5011)
KHOLCCEP_00412	4.66e-31	-	-	-	S	-	-	-	Parallel beta-helix repeats
KHOLCCEP_00413	2.34e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KHOLCCEP_00414	1.51e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHOLCCEP_00415	1.12e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
KHOLCCEP_00416	6.47e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
KHOLCCEP_00417	1.51e-227	-	-	-	T	-	-	-	Pfam Adenylate and Guanylate cyclase catalytic domain
KHOLCCEP_00418	3.81e-169	-	-	-	-	-	-	-	-
KHOLCCEP_00419	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KHOLCCEP_00420	1.26e-242	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHOLCCEP_00421	0.0	-	3.2.1.97	GH101	G	ko:K17624	-	ko00000,ko01000	Glycosyl hydrolase 101 beta sandwich domain
KHOLCCEP_00422	1.73e-253	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
KHOLCCEP_00423	5.79e-278	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KHOLCCEP_00424	1.38e-227	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
KHOLCCEP_00425	1.27e-221	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
KHOLCCEP_00426	8.55e-169	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
KHOLCCEP_00427	3.48e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHOLCCEP_00429	7.11e-295	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
KHOLCCEP_00430	6.1e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHOLCCEP_00431	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHOLCCEP_00432	2.67e-275	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
KHOLCCEP_00433	2.12e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
KHOLCCEP_00434	1.44e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
KHOLCCEP_00435	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
KHOLCCEP_00436	1.3e-300	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
KHOLCCEP_00437	9.55e-215	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
KHOLCCEP_00438	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
KHOLCCEP_00439	2.16e-208	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_00440	7.77e-74	-	-	-	-	-	-	-	-
KHOLCCEP_00441	2.24e-84	-	-	-	-	-	-	-	-
KHOLCCEP_00442	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
KHOLCCEP_00443	5.51e-239	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KHOLCCEP_00444	1.47e-303	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
KHOLCCEP_00445	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KHOLCCEP_00446	5.94e-107	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHOLCCEP_00447	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KHOLCCEP_00448	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
KHOLCCEP_00449	3.93e-230	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
KHOLCCEP_00450	2.69e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
KHOLCCEP_00451	5.51e-193	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
KHOLCCEP_00452	2.41e-185	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
KHOLCCEP_00453	5.39e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
KHOLCCEP_00454	1.12e-109	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHOLCCEP_00455	2.7e-184	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
KHOLCCEP_00456	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
KHOLCCEP_00457	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
KHOLCCEP_00458	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
KHOLCCEP_00459	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
KHOLCCEP_00461	2.19e-223	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHOLCCEP_00462	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
KHOLCCEP_00463	7.99e-193	-	-	-	-	-	-	-	-
KHOLCCEP_00464	5.45e-232	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
KHOLCCEP_00465	3.75e-310	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KHOLCCEP_00466	0.0	-	-	-	S	-	-	-	LPXTG-motif cell wall anchor domain protein
KHOLCCEP_00467	4.29e-130	-	-	-	L	-	-	-	Helix-turn-helix domain
KHOLCCEP_00468	2.18e-269	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KHOLCCEP_00469	6.55e-222	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
KHOLCCEP_00470	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
KHOLCCEP_00471	2.59e-201	-	-	-	O	-	-	-	Thioredoxin
KHOLCCEP_00473	3.12e-279	rpfB	-	-	S	ko:K21688	-	ko00000	G5
KHOLCCEP_00474	8.92e-218	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHOLCCEP_00475	3.79e-213	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHOLCCEP_00476	6.94e-146	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
KHOLCCEP_00477	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
KHOLCCEP_00478	3.18e-160	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
KHOLCCEP_00479	0.0	-	-	-	M	-	-	-	Conserved repeat domain
KHOLCCEP_00480	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
KHOLCCEP_00481	9.25e-257	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHOLCCEP_00482	5.66e-312	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KHOLCCEP_00483	1.05e-229	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
KHOLCCEP_00484	4.29e-161	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
KHOLCCEP_00485	4.15e-120	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
KHOLCCEP_00486	7.05e-226	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
KHOLCCEP_00487	3.88e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
KHOLCCEP_00488	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHOLCCEP_00489	1.15e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHOLCCEP_00490	6.53e-307	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHOLCCEP_00491	1.36e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
KHOLCCEP_00492	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHOLCCEP_00493	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHOLCCEP_00494	2.04e-104	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
KHOLCCEP_00497	4.34e-240	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
KHOLCCEP_00498	3.4e-242	-	-	-	K	-	-	-	Periplasmic binding protein domain
KHOLCCEP_00499	1.31e-290	-	-	-	I	-	-	-	Serine aminopeptidase, S33
KHOLCCEP_00500	9.05e-12	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KHOLCCEP_00501	2.38e-06	-	-	-	L	-	-	-	PFAM Integrase catalytic
KHOLCCEP_00503	1.08e-219	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KHOLCCEP_00504	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
KHOLCCEP_00505	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
KHOLCCEP_00506	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
KHOLCCEP_00507	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KHOLCCEP_00509	1.15e-112	-	-	-	Q	-	-	-	Acetyltransferase (GNAT) domain
KHOLCCEP_00510	6.93e-196	-	-	-	I	-	-	-	Serine aminopeptidase, S33
KHOLCCEP_00511	3.02e-70	-	-	-	S	-	-	-	Putative heavy-metal-binding
KHOLCCEP_00512	2.63e-59	-	-	-	D	-	-	-	DivIVA domain protein
KHOLCCEP_00513	9.44e-116	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
KHOLCCEP_00514	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
KHOLCCEP_00516	4.1e-251	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHOLCCEP_00518	1.92e-146	-	-	-	-	-	-	-	-
KHOLCCEP_00519	6.51e-214	-	-	-	EG	-	-	-	EamA-like transporter family
KHOLCCEP_00520	2.42e-263	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
KHOLCCEP_00521	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
KHOLCCEP_00522	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
KHOLCCEP_00523	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
KHOLCCEP_00524	3.69e-167	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
KHOLCCEP_00525	1.44e-122	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
KHOLCCEP_00526	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
KHOLCCEP_00527	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KHOLCCEP_00528	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
KHOLCCEP_00529	5.69e-234	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
KHOLCCEP_00530	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
KHOLCCEP_00531	9.5e-156	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
KHOLCCEP_00532	4.64e-295	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
KHOLCCEP_00533	2.05e-183	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
KHOLCCEP_00534	1.77e-93	crgA	-	-	D	-	-	-	Involved in cell division
KHOLCCEP_00535	0.0	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
KHOLCCEP_00536	3.68e-119	-	-	-	L	-	-	-	HTH-like domain
KHOLCCEP_00537	2.8e-185	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
KHOLCCEP_00538	7.68e-47	-	-	-	-	-	-	-	-
KHOLCCEP_00539	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KHOLCCEP_00540	5.53e-96	-	-	-	I	-	-	-	Sterol carrier protein
KHOLCCEP_00541	2.19e-60	-	-	-	L	ko:K07485	-	ko00000	Transposase
KHOLCCEP_00542	1.6e-57	istB	-	-	L	-	-	-	IstB-like ATP binding protein
KHOLCCEP_00543	7.04e-57	-	-	-	L	-	-	-	Integrase core domain
KHOLCCEP_00544	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
KHOLCCEP_00545	1.9e-17	-	-	-	-	-	-	-	-
KHOLCCEP_00546	6.82e-19	-	-	-	S	-	-	-	Putative phage holin Dp-1
KHOLCCEP_00547	1.65e-47	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
KHOLCCEP_00548	1.48e-35	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
KHOLCCEP_00550	4.3e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF2806)
KHOLCCEP_00552	6.66e-149	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
KHOLCCEP_00553	2.17e-83	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
KHOLCCEP_00554	4.64e-91	-	-	-	S	-	-	-	competence protein
KHOLCCEP_00555	1.07e-140	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
KHOLCCEP_00556	2.51e-217	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
KHOLCCEP_00557	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
KHOLCCEP_00558	1.09e-160	gntR	-	-	K	-	-	-	FCD
KHOLCCEP_00559	6.17e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHOLCCEP_00560	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	arabinose metabolic process
KHOLCCEP_00563	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
KHOLCCEP_00564	1.21e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KHOLCCEP_00565	1.03e-100	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHOLCCEP_00566	1.49e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KHOLCCEP_00567	0.0	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
KHOLCCEP_00568	3.08e-177	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
KHOLCCEP_00569	2.68e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
KHOLCCEP_00570	9.86e-241	-	-	-	EG	-	-	-	EamA-like transporter family
KHOLCCEP_00571	3.36e-306	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
KHOLCCEP_00572	9.37e-122	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KHOLCCEP_00573	5.83e-152	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
KHOLCCEP_00574	1.01e-137	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
KHOLCCEP_00575	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
KHOLCCEP_00576	2.71e-189	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
KHOLCCEP_00577	1.35e-104	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
KHOLCCEP_00578	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KHOLCCEP_00579	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
KHOLCCEP_00580	7.63e-228	-	-	-	S	-	-	-	Amidohydrolase family
KHOLCCEP_00581	6.78e-248	-	-	-	S	-	-	-	Protein conserved in bacteria
KHOLCCEP_00582	2.82e-260	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KHOLCCEP_00583	1.22e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
KHOLCCEP_00584	1.05e-114	-	-	-	K	-	-	-	LytTr DNA-binding domain
KHOLCCEP_00585	1.79e-79	-	-	-	T	-	-	-	protein histidine kinase activity
KHOLCCEP_00586	3.55e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHOLCCEP_00587	4.03e-39	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
KHOLCCEP_00588	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
KHOLCCEP_00589	2.06e-234	-	-	GT2	M	ko:K13670	-	ko00000,ko01000	Glycosyltransferase like family 2
KHOLCCEP_00590	5.96e-44	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
KHOLCCEP_00595	2.65e-169	-	-	-	M	-	-	-	NLP P60 protein
KHOLCCEP_00596	3.67e-88	-	-	-	S	-	-	-	SPP1 phage holin
KHOLCCEP_00598	3.47e-90	-	-	-	-	-	-	-	-
KHOLCCEP_00599	2.59e-32	-	-	-	L	-	-	-	DNA integration
KHOLCCEP_00600	6.83e-109	-	-	-	-	-	-	-	-
KHOLCCEP_00602	1.07e-295	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KHOLCCEP_00603	8.82e-136	-	-	-	-	-	-	-	-
KHOLCCEP_00604	1.51e-143	-	-	-	NT	-	-	-	phage tail tape measure protein
KHOLCCEP_00607	2.1e-84	-	-	-	N	-	-	-	domain, Protein
KHOLCCEP_00608	1.83e-48	-	-	-	-	-	-	-	-
KHOLCCEP_00610	1.23e-41	-	-	-	-	-	-	-	-
KHOLCCEP_00611	2.68e-19	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
KHOLCCEP_00612	3.88e-42	-	-	-	-	-	-	-	-
KHOLCCEP_00613	4.21e-190	-	-	-	S	-	-	-	Phage capsid family
KHOLCCEP_00614	2.87e-38	-	-	-	-	-	-	-	-
KHOLCCEP_00615	1.82e-61	-	-	-	-	-	-	-	-
KHOLCCEP_00616	7.48e-104	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
KHOLCCEP_00617	1.09e-184	-	-	-	S	-	-	-	Terminase
KHOLCCEP_00621	3.16e-82	-	-	-	EH	-	-	-	sulfate reduction
KHOLCCEP_00623	4.25e-24	-	-	-	V	-	-	-	HNH nucleases
KHOLCCEP_00625	7.34e-128	-	-	-	-	-	-	-	-
KHOLCCEP_00631	6e-08	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KHOLCCEP_00632	4.26e-47	-	-	-	V	-	-	-	HNH endonuclease
KHOLCCEP_00634	2.38e-81	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
KHOLCCEP_00637	2.25e-62	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
KHOLCCEP_00644	5.55e-05	-	-	-	-	-	-	-	-
KHOLCCEP_00645	3.31e-107	-	-	-	S	-	-	-	KilA-N
KHOLCCEP_00646	5.58e-45	-	-	-	-	-	-	-	-
KHOLCCEP_00647	7.95e-90	-	-	-	-	-	-	-	-
KHOLCCEP_00648	7.16e-75	-	-	-	-	-	-	-	-
KHOLCCEP_00649	1.62e-140	int8	-	-	L	-	-	-	Phage integrase family
KHOLCCEP_00650	3.89e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KHOLCCEP_00651	7.01e-272	-	-	-	G	-	-	-	Transmembrane secretion effector
KHOLCCEP_00652	5.64e-257	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHOLCCEP_00653	1.98e-119	-	-	-	-	-	-	-	-
KHOLCCEP_00654	1.76e-41	-	-	-	L	-	-	-	NUDIX domain
KHOLCCEP_00655	3.09e-289	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
KHOLCCEP_00656	0.0	glfT	2.4.1.288	GT2	S	ko:K16650	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
KHOLCCEP_00657	4.03e-301	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLCCEP_00658	3.48e-188	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
KHOLCCEP_00659	7.52e-230	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
KHOLCCEP_00660	1.1e-175	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KHOLCCEP_00661	1.06e-268	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
KHOLCCEP_00662	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
KHOLCCEP_00663	2.26e-227	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 9.99
KHOLCCEP_00664	3.86e-31	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KHOLCCEP_00665	2.65e-74	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase activity
KHOLCCEP_00666	1.31e-119	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
KHOLCCEP_00667	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
KHOLCCEP_00668	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KHOLCCEP_00669	1.79e-286	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KHOLCCEP_00670	5.06e-80	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_00671	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
KHOLCCEP_00672	4.85e-185	istB	-	-	L	-	-	-	IstB-like ATP binding protein
KHOLCCEP_00673	8.51e-206	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
KHOLCCEP_00674	2.6e-185	istB	-	-	L	-	-	-	IstB-like ATP binding protein
KHOLCCEP_00675	1.9e-69	-	-	-	L	-	-	-	Helix-turn-helix domain
KHOLCCEP_00676	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
KHOLCCEP_00677	7.52e-239	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
KHOLCCEP_00678	9.04e-186	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KHOLCCEP_00679	2.23e-164	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHOLCCEP_00680	1.78e-120	-	-	-	D	-	-	-	nuclear chromosome segregation
KHOLCCEP_00681	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KHOLCCEP_00682	3.16e-235	-	-	-	L	-	-	-	Excalibur calcium-binding domain
KHOLCCEP_00683	4.83e-278	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KHOLCCEP_00684	4.48e-312	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KHOLCCEP_00685	2.63e-142	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KHOLCCEP_00686	2.08e-304	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KHOLCCEP_00687	8.96e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHOLCCEP_00688	2.89e-308	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
KHOLCCEP_00689	1.33e-165	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
KHOLCCEP_00690	1.71e-262	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
KHOLCCEP_00691	8.51e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KHOLCCEP_00692	6.61e-234	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
KHOLCCEP_00693	1.29e-189	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHOLCCEP_00694	1.76e-216	-	-	-	S	-	-	-	Protein conserved in bacteria
KHOLCCEP_00696	5.92e-313	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
KHOLCCEP_00698	0.0	-	-	-	G	-	-	-	BNR repeat-like domain
KHOLCCEP_00699	1.45e-235	xynB2	1.1.1.169	-	E	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	lipolytic protein G-D-S-L family
KHOLCCEP_00700	5.06e-115	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHOLCCEP_00701	5.13e-61	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHOLCCEP_00703	0.0	-	-	-	T	-	-	-	Forkhead associated domain
KHOLCCEP_00704	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
KHOLCCEP_00705	2.87e-56	-	-	-	-	-	-	-	-
KHOLCCEP_00706	3.49e-140	-	-	-	NO	-	-	-	SAF
KHOLCCEP_00707	1.88e-51	-	-	-	S	-	-	-	Putative regulatory protein
KHOLCCEP_00708	3.43e-155	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
KHOLCCEP_00709	1.2e-191	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KHOLCCEP_00710	1.35e-264	-	-	-	-	-	-	-	-
KHOLCCEP_00711	3.49e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHOLCCEP_00712	7.06e-170	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
KHOLCCEP_00713	3.14e-36	-	-	-	KLT	-	-	-	Associated with various cellular activities
KHOLCCEP_00717	2.71e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
KHOLCCEP_00718	4.5e-279	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
KHOLCCEP_00719	3.55e-81	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
KHOLCCEP_00720	2.24e-282	dapC	-	-	E	-	-	-	Aminotransferase class I and II
KHOLCCEP_00721	2.07e-309	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHOLCCEP_00723	0.0	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
KHOLCCEP_00724	2.32e-146	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
KHOLCCEP_00725	7.22e-153	-	-	-	-	-	-	-	-
KHOLCCEP_00726	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
KHOLCCEP_00727	2.64e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHOLCCEP_00728	1.71e-99	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
KHOLCCEP_00729	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
KHOLCCEP_00730	3.54e-297	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
KHOLCCEP_00731	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KHOLCCEP_00732	1.36e-213	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
KHOLCCEP_00734	1.23e-23	-	-	-	S	-	-	-	YwiC-like protein
KHOLCCEP_00735	5.42e-67	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
KHOLCCEP_00736	6.65e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHOLCCEP_00737	1.34e-154	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
KHOLCCEP_00738	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHOLCCEP_00739	1.15e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHOLCCEP_00740	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHOLCCEP_00741	2.21e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHOLCCEP_00742	2.73e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHOLCCEP_00743	2.71e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHOLCCEP_00744	6.77e-51	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
KHOLCCEP_00745	9.4e-57	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHOLCCEP_00746	7.32e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHOLCCEP_00747	9.32e-70	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHOLCCEP_00748	1.6e-133	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHOLCCEP_00749	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHOLCCEP_00750	9.65e-91	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHOLCCEP_00751	2.69e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHOLCCEP_00752	1.53e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHOLCCEP_00753	2.04e-149	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHOLCCEP_00754	1.46e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
KHOLCCEP_00755	1.51e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
KHOLCCEP_00756	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHOLCCEP_00757	4.79e-129	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHOLCCEP_00758	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHOLCCEP_00759	1.03e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
KHOLCCEP_00760	6.96e-83	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHOLCCEP_00761	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHOLCCEP_00762	1.4e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHOLCCEP_00763	2.18e-94	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
KHOLCCEP_00764	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
KHOLCCEP_00765	4.08e-221	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHOLCCEP_00766	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
KHOLCCEP_00767	5.51e-199	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
KHOLCCEP_00769	1.05e-167	tnp3503b	-	-	L	-	-	-	Transposase and inactivated derivatives
KHOLCCEP_00770	1.81e-224	-	-	-	-	-	-	-	-
KHOLCCEP_00771	1.16e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
KHOLCCEP_00772	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHOLCCEP_00773	8.76e-124	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHOLCCEP_00774	5.27e-298	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHOLCCEP_00775	1.35e-299	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
KHOLCCEP_00776	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHOLCCEP_00777	8.06e-141	-	-	-	-	-	-	-	-
KHOLCCEP_00778	5.18e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
KHOLCCEP_00779	1.28e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHOLCCEP_00780	2.06e-259	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHOLCCEP_00781	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
KHOLCCEP_00782	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHOLCCEP_00783	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
KHOLCCEP_00787	4.73e-05	-	-	-	O	ko:K18546	-	ko00000,ko01000,ko01002	Peptidase s1 and s6 chymotrypsin hap
KHOLCCEP_00788	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
KHOLCCEP_00789	6.49e-121	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KHOLCCEP_00790	3.25e-273	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
KHOLCCEP_00791	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
KHOLCCEP_00792	3.29e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHOLCCEP_00794	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
KHOLCCEP_00796	2.61e-122	-	-	-	-	-	-	-	-
KHOLCCEP_00797	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHOLCCEP_00798	4.36e-239	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
KHOLCCEP_00799	2.48e-182	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
KHOLCCEP_00800	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHOLCCEP_00801	7.83e-162	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
KHOLCCEP_00802	0.0	tcsS3	-	-	KT	-	-	-	PspC domain
KHOLCCEP_00803	0.0	pspC	-	-	KT	-	-	-	PspC domain
KHOLCCEP_00804	9.16e-196	-	-	-	-	-	-	-	-
KHOLCCEP_00805	2.25e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
KHOLCCEP_00806	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
KHOLCCEP_00807	4.5e-279	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
KHOLCCEP_00809	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
KHOLCCEP_00810	2.37e-223	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
KHOLCCEP_00811	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHOLCCEP_00813	6.57e-153	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KHOLCCEP_00814	4.1e-291	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHOLCCEP_00815	4.6e-53	-	-	-	-	-	-	-	-
KHOLCCEP_00816	1.41e-274	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHOLCCEP_00817	1.1e-233	-	-	-	S	-	-	-	CHAP domain
KHOLCCEP_00818	4.53e-158	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
KHOLCCEP_00819	5.33e-244	-	-	-	T	-	-	-	Universal stress protein family
KHOLCCEP_00820	5.29e-95	-	-	-	O	-	-	-	OsmC-like protein
KHOLCCEP_00821	8.63e-224	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHOLCCEP_00822	5.46e-165	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
KHOLCCEP_00823	3.32e-124	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
KHOLCCEP_00824	4.43e-250	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KHOLCCEP_00825	1.14e-52	-	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
KHOLCCEP_00826	5.06e-145	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLCCEP_00827	2.52e-266	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
KHOLCCEP_00828	2.53e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KHOLCCEP_00829	2.87e-14	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
KHOLCCEP_00830	1.23e-231	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
KHOLCCEP_00831	2.35e-76	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
KHOLCCEP_00832	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
KHOLCCEP_00833	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
KHOLCCEP_00835	6.71e-196	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHOLCCEP_00836	5.63e-255	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHOLCCEP_00837	3.43e-105	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
KHOLCCEP_00840	1.48e-271	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
KHOLCCEP_00841	1.89e-227	-	-	-	M	-	-	-	Glycosyltransferase like family 2
KHOLCCEP_00842	0.0	-	-	-	S	-	-	-	AI-2E family transporter
KHOLCCEP_00843	3.97e-295	-	-	-	M	-	-	-	Glycosyl transferase family 21
KHOLCCEP_00844	2.64e-214	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_00845	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
KHOLCCEP_00846	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
KHOLCCEP_00847	3.48e-269	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHOLCCEP_00848	2.65e-127	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHOLCCEP_00849	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHOLCCEP_00850	2.05e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
KHOLCCEP_00851	3.21e-210	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHOLCCEP_00852	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHOLCCEP_00853	5.53e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
KHOLCCEP_00854	1.88e-219	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
KHOLCCEP_00855	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	hydrolase family 20, catalytic
KHOLCCEP_00856	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
KHOLCCEP_00857	1.43e-214	-	-	-	M	-	-	-	domain, Protein
KHOLCCEP_00858	4.33e-162	-	-	-	-	-	-	-	-
KHOLCCEP_00859	4.32e-148	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHOLCCEP_00860	1.81e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
KHOLCCEP_00861	4.3e-42	-	-	-	S	-	-	-	DUF218 domain
KHOLCCEP_00862	5.12e-77	-	-	-	S	-	-	-	DUF218 domain
KHOLCCEP_00864	9.14e-146	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
KHOLCCEP_00865	7.23e-202	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KHOLCCEP_00866	3.03e-21	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
KHOLCCEP_00867	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
KHOLCCEP_00868	3.68e-229	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
KHOLCCEP_00870	1.52e-91	-	-	-	EGP	-	-	-	Major facilitator superfamily
KHOLCCEP_00871	1.12e-47	-	-	-	C	-	-	-	Aldo/keto reductase family
KHOLCCEP_00872	0.0	-	2.5.1.49	-	H	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.98
KHOLCCEP_00873	1.04e-270	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
KHOLCCEP_00874	9.17e-37	-	-	-	L	-	-	-	Transposase
KHOLCCEP_00876	1.12e-188	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
KHOLCCEP_00877	1.33e-91	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KHOLCCEP_00878	4e-11	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KHOLCCEP_00879	2.88e-209	-	-	-	EG	-	-	-	EamA-like transporter family
KHOLCCEP_00880	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
KHOLCCEP_00881	7.95e-189	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
KHOLCCEP_00882	2.28e-218	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
KHOLCCEP_00883	8.81e-165	-	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
KHOLCCEP_00884	4.16e-143	-	-	-	-	-	-	-	-
KHOLCCEP_00885	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
KHOLCCEP_00886	3.32e-240	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
KHOLCCEP_00887	2.74e-209	-	-	-	G	ko:K05340	-	ko00000,ko02000	Sugar transport protein
KHOLCCEP_00888	1.27e-247	-	-	-	K	ko:K13633	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
KHOLCCEP_00890	1.85e-48	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
KHOLCCEP_00891	2.35e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHOLCCEP_00892	3.73e-240	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHOLCCEP_00893	3.71e-78	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide repeat protein
KHOLCCEP_00894	7.44e-151	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
KHOLCCEP_00895	1.5e-260	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
KHOLCCEP_00896	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KHOLCCEP_00897	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
KHOLCCEP_00898	1.91e-156	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KHOLCCEP_00899	2.34e-204	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KHOLCCEP_00900	0.0	-	-	-	L	-	-	-	PIF1-like helicase
KHOLCCEP_00902	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHOLCCEP_00903	6.44e-55	-	-	-	-	-	-	-	-
KHOLCCEP_00904	3.83e-152	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
KHOLCCEP_00905	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
KHOLCCEP_00906	1.4e-189	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
KHOLCCEP_00907	6.17e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
KHOLCCEP_00908	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
KHOLCCEP_00909	2.4e-130	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
KHOLCCEP_00910	1.04e-249	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
KHOLCCEP_00911	2.84e-71	-	-	-	K	-	-	-	MerR, DNA binding
KHOLCCEP_00912	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
KHOLCCEP_00913	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_00914	7.52e-283	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KHOLCCEP_00915	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
KHOLCCEP_00916	3.15e-298	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
KHOLCCEP_00917	1.81e-310	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
KHOLCCEP_00918	1.77e-178	hflK	-	-	O	-	-	-	prohibitin homologues
KHOLCCEP_00919	5.27e-100	-	-	-	L	-	-	-	Transposase
KHOLCCEP_00920	2.85e-33	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
KHOLCCEP_00921	1.96e-313	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system methyltransferase subunit()
KHOLCCEP_00922	9.53e-72	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
KHOLCCEP_00923	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
KHOLCCEP_00924	9.7e-73	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
KHOLCCEP_00925	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHOLCCEP_00927	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
KHOLCCEP_00928	2.6e-25	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KHOLCCEP_00929	2.17e-243	-	-	-	K	-	-	-	Periplasmic binding protein domain
KHOLCCEP_00930	2.09e-54	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
KHOLCCEP_00931	7.46e-75	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
KHOLCCEP_00932	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
KHOLCCEP_00933	5.6e-75	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
KHOLCCEP_00934	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KHOLCCEP_00935	7.6e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHOLCCEP_00936	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
KHOLCCEP_00937	3.46e-218	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_00938	2.9e-207	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_00939	2.29e-182	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
KHOLCCEP_00940	1.06e-197	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_00941	5.95e-239	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHOLCCEP_00944	7.91e-51	-	-	-	GK	-	-	-	ROK family
KHOLCCEP_00945	5.85e-27	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_00946	2.81e-252	-	-	-	L	-	-	-	PFAM Integrase catalytic
KHOLCCEP_00947	2.58e-130	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
KHOLCCEP_00948	6.85e-214	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
KHOLCCEP_00949	1.26e-55	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
KHOLCCEP_00950	3.47e-128	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
KHOLCCEP_00951	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHOLCCEP_00952	1.21e-241	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHOLCCEP_00953	2.14e-92	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
KHOLCCEP_00954	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
KHOLCCEP_00955	1.78e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
KHOLCCEP_00956	9.98e-147	xylR	-	-	K	ko:K02529	-	ko00000,ko03000	purine nucleotide biosynthetic process
KHOLCCEP_00957	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KHOLCCEP_00958	8.32e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHOLCCEP_00959	9.01e-155	-	-	-	-	-	-	-	-
KHOLCCEP_00960	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
KHOLCCEP_00962	4.39e-209	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
KHOLCCEP_00963	6.53e-127	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHOLCCEP_00964	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
KHOLCCEP_00965	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
KHOLCCEP_00966	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
KHOLCCEP_00967	8.71e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
KHOLCCEP_00968	4.55e-194	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
KHOLCCEP_00969	0.0	-	-	-	-	-	-	-	-
KHOLCCEP_00970	8.27e-187	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
KHOLCCEP_00971	2.26e-130	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KHOLCCEP_00972	1.39e-66	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
KHOLCCEP_00973	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHOLCCEP_00974	7.83e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHOLCCEP_00975	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHOLCCEP_00976	2.81e-192	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHOLCCEP_00977	7.5e-98	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHOLCCEP_00978	1.21e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHOLCCEP_00980	3.54e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
KHOLCCEP_00981	4.87e-264	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHOLCCEP_00983	8.85e-47	-	-	-	-	-	-	-	-
KHOLCCEP_00984	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
KHOLCCEP_00985	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
KHOLCCEP_00986	1.13e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KHOLCCEP_00988	9.17e-131	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
KHOLCCEP_00989	5.6e-170	-	-	-	-	-	-	-	-
KHOLCCEP_00990	3.61e-171	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
KHOLCCEP_00991	4.39e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHOLCCEP_00992	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
KHOLCCEP_00993	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHOLCCEP_00994	0.0	-	-	-	S	-	-	-	domain protein
KHOLCCEP_00995	9.37e-96	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
KHOLCCEP_00996	5.4e-118	lrp_3	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
KHOLCCEP_00997	6.88e-297	-	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
KHOLCCEP_00998	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHOLCCEP_00999	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
KHOLCCEP_01001	6.51e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
KHOLCCEP_01002	1.96e-251	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KHOLCCEP_01003	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHOLCCEP_01004	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHOLCCEP_01005	3.33e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHOLCCEP_01007	1.94e-79	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KHOLCCEP_01008	1.94e-213	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
KHOLCCEP_01009	4.99e-164	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHOLCCEP_01010	1.45e-297	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
KHOLCCEP_01011	6.68e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
KHOLCCEP_01012	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
KHOLCCEP_01013	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
KHOLCCEP_01014	3.15e-44	-	-	-	S	-	-	-	granule-associated protein
KHOLCCEP_01015	1.02e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
KHOLCCEP_01016	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
KHOLCCEP_01017	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
KHOLCCEP_01018	0.0	dinF	-	-	V	-	-	-	MatE
KHOLCCEP_01019	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
KHOLCCEP_01020	2.56e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
KHOLCCEP_01021	2.1e-305	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
KHOLCCEP_01022	2.48e-276	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHOLCCEP_01024	7.87e-171	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KHOLCCEP_01025	6.85e-255	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
KHOLCCEP_01026	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
KHOLCCEP_01027	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
KHOLCCEP_01029	2.63e-118	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
KHOLCCEP_01030	1.23e-109	-	-	-	-	-	-	-	-
KHOLCCEP_01031	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
KHOLCCEP_01032	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KHOLCCEP_01033	2.29e-106	-	-	-	K	-	-	-	Winged helix DNA-binding domain
KHOLCCEP_01034	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
KHOLCCEP_01035	3.51e-244	-	-	-	M	ko:K20276	ko02024,map02024	ko00000,ko00001	chlorophyll binding
KHOLCCEP_01036	4.87e-270	-	-	-	M	ko:K20276	ko02024,map02024	ko00000,ko00001	chlorophyll binding
KHOLCCEP_01037	4.6e-85	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
KHOLCCEP_01041	1.72e-209	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KHOLCCEP_01042	1.13e-307	-	-	-	S	-	-	-	Putative ABC-transporter type IV
KHOLCCEP_01043	2.24e-103	-	-	-	-	-	-	-	-
KHOLCCEP_01044	5.06e-34	-	-	-	Q	-	-	-	phosphatase activity
KHOLCCEP_01045	5.02e-11	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KHOLCCEP_01046	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
KHOLCCEP_01047	9.05e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
KHOLCCEP_01048	1.2e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KHOLCCEP_01049	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHOLCCEP_01050	9.66e-88	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KHOLCCEP_01051	1.5e-167	-	-	-	K	ko:K03489,ko:K03710	-	ko00000,ko03000	UTRA
KHOLCCEP_01052	1.15e-102	-	-	-	S	-	-	-	FMN_bind
KHOLCCEP_01053	7.76e-191	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLCCEP_01054	2.51e-273	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KHOLCCEP_01055	1.08e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KHOLCCEP_01056	8.34e-294	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
KHOLCCEP_01057	4.8e-150	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
KHOLCCEP_01058	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
KHOLCCEP_01059	5.86e-31	-	-	-	G	-	-	-	MFS/sugar transport protein
KHOLCCEP_01060	1.01e-256	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHOLCCEP_01061	1.2e-48	-	-	-	S	-	-	-	Fic/DOC family
KHOLCCEP_01062	2.75e-94	-	-	-	S	-	-	-	Fic/DOC family
KHOLCCEP_01063	2.67e-208	-	-	-	L	-	-	-	Transposase, Mutator family
KHOLCCEP_01064	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHOLCCEP_01065	4.22e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
KHOLCCEP_01066	1.14e-256	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KHOLCCEP_01067	5.19e-273	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KHOLCCEP_01068	6.97e-157	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHOLCCEP_01069	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHOLCCEP_01070	1.6e-251	-	-	-	I	-	-	-	PAP2 superfamily
KHOLCCEP_01071	0.0	-	-	-	M	-	-	-	PA domain
KHOLCCEP_01072	9.41e-175	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
KHOLCCEP_01073	6.29e-296	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
KHOLCCEP_01074	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
KHOLCCEP_01075	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHOLCCEP_01076	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KHOLCCEP_01077	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
KHOLCCEP_01078	1.77e-148	-	-	-	-	-	-	-	-
KHOLCCEP_01079	6.5e-270	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHOLCCEP_01081	1.42e-126	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
KHOLCCEP_01082	2.29e-176	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
KHOLCCEP_01083	1.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHOLCCEP_01084	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
KHOLCCEP_01085	3.25e-274	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
KHOLCCEP_01086	1.04e-72	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
KHOLCCEP_01087	3.96e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
KHOLCCEP_01088	1.3e-20	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
KHOLCCEP_01090	2.62e-157	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
KHOLCCEP_01091	1.12e-242	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
KHOLCCEP_01092	1.34e-196	-	-	-	D	-	-	-	bacterial-type flagellum organization
KHOLCCEP_01094	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KHOLCCEP_01095	5.71e-257	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
KHOLCCEP_01096	8.69e-129	-	-	-	-	-	-	-	-
KHOLCCEP_01097	9.1e-39	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KHOLCCEP_01098	1.29e-267	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
KHOLCCEP_01099	0.0	-	-	-	-	-	-	-	-
KHOLCCEP_01100	2.41e-37	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
KHOLCCEP_01101	1.12e-210	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KHOLCCEP_01102	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
KHOLCCEP_01103	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
KHOLCCEP_01104	0.0	-	-	-	V	-	-	-	ABC transporter permease
KHOLCCEP_01105	1.91e-261	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
KHOLCCEP_01106	3.28e-176	-	-	-	T	ko:K06950	-	ko00000	HD domain
KHOLCCEP_01107	4.56e-209	-	-	-	S	-	-	-	Glutamine amidotransferase domain
KHOLCCEP_01109	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KHOLCCEP_01110	5.49e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
KHOLCCEP_01111	4.8e-166	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
KHOLCCEP_01112	9.51e-76	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
KHOLCCEP_01113	8.98e-51	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
KHOLCCEP_01114	3.73e-105	-	-	-	K	-	-	-	Transcriptional regulator
KHOLCCEP_01115	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHOLCCEP_01116	9.35e-171	-	-	-	-	-	-	-	-
KHOLCCEP_01117	2.27e-83	-	-	-	-	-	-	-	-
KHOLCCEP_01118	1.87e-221	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHOLCCEP_01119	1.54e-162	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
KHOLCCEP_01121	1.17e-171	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
KHOLCCEP_01122	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat
KHOLCCEP_01123	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
KHOLCCEP_01124	2.62e-111	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
KHOLCCEP_01125	1.35e-236	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
KHOLCCEP_01126	3.29e-80	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHOLCCEP_01127	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
KHOLCCEP_01128	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
KHOLCCEP_01129	1.36e-243	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
KHOLCCEP_01132	1.84e-180	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
KHOLCCEP_01133	5.82e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
KHOLCCEP_01134	1.82e-180	nfrA	-	-	C	-	-	-	Nitroreductase family
KHOLCCEP_01135	2.45e-61	-	-	-	-	-	-	-	-
KHOLCCEP_01136	3.47e-57	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
KHOLCCEP_01138	5.52e-215	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
KHOLCCEP_01139	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_01140	8.65e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
KHOLCCEP_01141	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHOLCCEP_01142	6.57e-97	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHOLCCEP_01143	1.82e-179	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KHOLCCEP_01144	2.19e-291	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KHOLCCEP_01145	1.27e-226	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
KHOLCCEP_01146	7.62e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHOLCCEP_01147	6.31e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
KHOLCCEP_01148	2.6e-163	-	-	-	S	-	-	-	alpha beta
KHOLCCEP_01149	4.78e-188	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHOLCCEP_01150	3.07e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
KHOLCCEP_01151	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHOLCCEP_01152	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
KHOLCCEP_01153	5.1e-118	-	-	-	-	-	-	-	-
KHOLCCEP_01154	1.59e-255	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
KHOLCCEP_01155	1.35e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
KHOLCCEP_01156	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
KHOLCCEP_01157	0.0	fadD1	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
KHOLCCEP_01158	3.75e-165	-	-	-	M	-	-	-	Peptidase family M23
KHOLCCEP_01160	1.13e-250	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHOLCCEP_01161	7.03e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
KHOLCCEP_01162	1.25e-206	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
KHOLCCEP_01163	7.36e-152	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
KHOLCCEP_01164	1.05e-231	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
KHOLCCEP_01165	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
KHOLCCEP_01166	3.26e-166	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
KHOLCCEP_01167	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
KHOLCCEP_01168	7.24e-212	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
KHOLCCEP_01169	1.72e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KHOLCCEP_01170	4.05e-207	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
KHOLCCEP_01171	0.0	-	-	-	E	-	-	-	Serine carboxypeptidase
KHOLCCEP_01172	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
KHOLCCEP_01173	6.6e-188	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
KHOLCCEP_01174	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
KHOLCCEP_01175	8.85e-209	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KHOLCCEP_01176	8.22e-85	-	-	-	K	-	-	-	Protein of unknown function, DUF488
KHOLCCEP_01177	1.35e-154	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KHOLCCEP_01178	6.56e-118	-	-	-	K	-	-	-	FR47-like protein
KHOLCCEP_01179	6.33e-22	-	-	-	K	-	-	-	Transcriptional regulator
KHOLCCEP_01180	4.24e-58	-	-	-	F	-	-	-	Hydrolase of X-linked nucleoside diphosphate N terminal
KHOLCCEP_01182	1.01e-90	-	-	-	-	-	-	-	-
KHOLCCEP_01184	6.93e-236	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
KHOLCCEP_01185	2.88e-98	qseC	2.7.13.3	-	T	ko:K02484,ko:K07637,ko:K07643,ko:K07645,ko:K07649,ko:K07653,ko:K18351	ko01502,ko01503,ko02020,ko02024,map01502,map01503,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	Histidine kinase
KHOLCCEP_01186	9.44e-169	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
KHOLCCEP_01187	8.05e-166	-	-	-	-	-	-	-	-
KHOLCCEP_01188	3.92e-105	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHOLCCEP_01189	7.99e-226	-	-	-	M	-	-	-	heme binding
KHOLCCEP_01190	9.78e-122	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
KHOLCCEP_01192	7.22e-203	-	-	-	-	-	-	-	-
KHOLCCEP_01193	2.38e-127	-	-	-	S	-	-	-	Putative ABC-transporter type IV
KHOLCCEP_01194	5.99e-143	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
KHOLCCEP_01195	4.58e-246	-	-	-	V	-	-	-	VanZ like family
KHOLCCEP_01196	4.46e-188	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
KHOLCCEP_01197	3.34e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
KHOLCCEP_01198	1.25e-187	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
KHOLCCEP_01199	8.09e-170	-	-	-	C	-	-	-	Putative TM nitroreductase
KHOLCCEP_01200	5.43e-164	-	-	-	-	-	-	-	-
KHOLCCEP_01202	0.0	treS_1	-	-	G	-	-	-	Alpha amylase, catalytic domain
KHOLCCEP_01203	1.08e-101	-	-	-	S	-	-	-	Bacterial PH domain
KHOLCCEP_01204	4.04e-178	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
KHOLCCEP_01205	6.1e-89	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHOLCCEP_01206	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHOLCCEP_01208	6.24e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHOLCCEP_01209	3.43e-186	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHOLCCEP_01210	1.48e-119	-	-	-	-	-	-	-	-
KHOLCCEP_01211	9.8e-298	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHOLCCEP_01212	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
KHOLCCEP_01213	3.78e-157	-	-	-	S	-	-	-	ABC-2 family transporter protein
KHOLCCEP_01214	1.47e-159	-	-	-	S	-	-	-	ABC-2 family transporter protein
KHOLCCEP_01215	5.2e-226	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_01216	6.98e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
KHOLCCEP_01217	3.57e-158	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
KHOLCCEP_01218	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
KHOLCCEP_01219	3.15e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHOLCCEP_01220	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
KHOLCCEP_01221	5.24e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
KHOLCCEP_01222	1.07e-141	-	-	-	-	-	-	-	-
KHOLCCEP_01223	5.4e-174	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
KHOLCCEP_01225	1.25e-241	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
KHOLCCEP_01226	3.74e-261	-	-	-	L	-	-	-	Tetratricopeptide repeat
KHOLCCEP_01227	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHOLCCEP_01228	2.05e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
KHOLCCEP_01229	3.22e-140	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KHOLCCEP_01230	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
KHOLCCEP_01231	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KHOLCCEP_01232	2.28e-288	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
KHOLCCEP_01233	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
KHOLCCEP_01234	1.51e-136	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
KHOLCCEP_01235	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	modification (methylase) protein of type I restriction-modification system K03427
KHOLCCEP_01236	4.29e-197	-	-	-	S	-	-	-	Domain of unknown function (DUF4357)
KHOLCCEP_01237	2e-41	-	-	-	-	-	-	-	-
KHOLCCEP_01238	1.35e-226	-	-	-	L	-	-	-	Phage integrase family
KHOLCCEP_01239	5.96e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
KHOLCCEP_01240	1.29e-112	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KHOLCCEP_01241	2.51e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHOLCCEP_01242	1.97e-313	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
KHOLCCEP_01243	4.12e-227	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
KHOLCCEP_01244	2.58e-275	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KHOLCCEP_01245	1.58e-261	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KHOLCCEP_01246	2.99e-138	-	-	-	-	-	-	-	-
KHOLCCEP_01247	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
KHOLCCEP_01248	1.51e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHOLCCEP_01249	1.92e-206	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHOLCCEP_01250	1.43e-174	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_01251	2.65e-175	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
KHOLCCEP_01252	8.2e-68	-	-	-	IQ	-	-	-	oxidoreductase activity
KHOLCCEP_01254	4.47e-75	-	-	-	K	-	-	-	AraC-like ligand binding domain
KHOLCCEP_01255	1.12e-303	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
KHOLCCEP_01256	1.72e-204	-	-	-	G	-	-	-	Phosphoglycerate mutase family
KHOLCCEP_01257	1.22e-72	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
KHOLCCEP_01258	4.33e-238	-	-	-	S	-	-	-	Conserved hypothetical protein 698
KHOLCCEP_01259	8.63e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
KHOLCCEP_01260	5.28e-152	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
KHOLCCEP_01261	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
KHOLCCEP_01263	0.0	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain
KHOLCCEP_01264	4.32e-160	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
KHOLCCEP_01265	1.5e-96	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
KHOLCCEP_01266	1.21e-48	-	-	-	-	-	-	-	-
KHOLCCEP_01267	1.66e-46	-	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KHOLCCEP_01268	7.03e-86	-	-	-	S	-	-	-	Zincin-like metallopeptidase
KHOLCCEP_01269	1.37e-116	-	-	-	S	-	-	-	Helix-turn-helix
KHOLCCEP_01270	6.35e-263	-	-	-	S	-	-	-	Short C-terminal domain
KHOLCCEP_01271	1.1e-30	-	-	-	-	-	-	-	-
KHOLCCEP_01274	6.04e-103	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
KHOLCCEP_01275	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
KHOLCCEP_01276	6.01e-108	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
KHOLCCEP_01277	1.05e-199	-	-	-	J	-	-	-	Methyltransferase domain
KHOLCCEP_01278	5.59e-78	yccF	-	-	S	-	-	-	Inner membrane component domain
KHOLCCEP_01279	7.83e-162	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
KHOLCCEP_01280	4.82e-315	-	-	-	K	-	-	-	Fic/DOC family
KHOLCCEP_01281	7.17e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHOLCCEP_01282	2.11e-291	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
KHOLCCEP_01283	9.77e-123	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_01284	1.64e-262	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHOLCCEP_01285	9.06e-235	acoB	1.2.4.1, 1.2.4.4	-	C	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
KHOLCCEP_01286	5.2e-237	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
KHOLCCEP_01287	6.33e-188	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
KHOLCCEP_01288	2.08e-213	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
KHOLCCEP_01289	3.01e-183	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHOLCCEP_01290	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
KHOLCCEP_01291	0.0	-	-	-	T	-	-	-	Histidine kinase
KHOLCCEP_01292	2.92e-171	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
KHOLCCEP_01293	0.0	-	-	-	I	-	-	-	PAP2 superfamily
KHOLCCEP_01294	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
KHOLCCEP_01295	3.03e-211	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KHOLCCEP_01296	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
KHOLCCEP_01297	9.86e-202	-	-	-	S	-	-	-	Putative ABC-transporter type IV
KHOLCCEP_01298	4.22e-211	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
KHOLCCEP_01299	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
KHOLCCEP_01300	1.52e-75	-	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
KHOLCCEP_01301	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
KHOLCCEP_01302	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
KHOLCCEP_01303	2.23e-93	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
KHOLCCEP_01304	3.57e-235	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
KHOLCCEP_01305	1.01e-150	safC	-	-	S	-	-	-	O-methyltransferase
KHOLCCEP_01306	1.73e-221	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
KHOLCCEP_01307	1.67e-290	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KHOLCCEP_01308	4.28e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
KHOLCCEP_01311	2.04e-310	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHOLCCEP_01312	9.32e-164	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHOLCCEP_01313	4.05e-147	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHOLCCEP_01315	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
KHOLCCEP_01316	9.36e-310	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHOLCCEP_01317	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
KHOLCCEP_01318	1.94e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
KHOLCCEP_01319	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHOLCCEP_01320	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
KHOLCCEP_01321	2.33e-53	-	-	-	-	-	-	-	-
KHOLCCEP_01322	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHOLCCEP_01323	5.72e-285	-	-	-	S	-	-	-	Peptidase dimerisation domain
KHOLCCEP_01324	1.49e-121	-	-	-	P	-	-	-	ABC-type metal ion transport system permease component
KHOLCCEP_01325	7.9e-212	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KHOLCCEP_01326	1.53e-152	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHOLCCEP_01327	3.09e-89	-	-	-	-	-	-	-	-
KHOLCCEP_01330	6.92e-41	-	-	-	-	-	-	-	-
KHOLCCEP_01331	2.24e-23	-	-	-	-	-	-	-	-
KHOLCCEP_01332	1.29e-259	-	-	-	S	-	-	-	Helix-turn-helix domain
KHOLCCEP_01333	3.71e-55	-	-	-	-	-	-	-	-
KHOLCCEP_01334	6.03e-119	-	-	-	S	-	-	-	Transcription factor WhiB
KHOLCCEP_01335	2.09e-150	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
KHOLCCEP_01336	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
KHOLCCEP_01337	5.33e-36	-	-	-	-	-	-	-	-
KHOLCCEP_01338	1.34e-177	-	-	-	-	-	-	-	-
KHOLCCEP_01339	6.15e-84	-	-	-	S	-	-	-	PrgI family protein
KHOLCCEP_01340	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
KHOLCCEP_01341	6.3e-268	-	-	-	M	-	-	-	CHAP domain
KHOLCCEP_01343	1.17e-212	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
KHOLCCEP_01345	7.32e-124	-	-	-	K	-	-	-	Helix-turn-helix domain protein
KHOLCCEP_01347	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
KHOLCCEP_01348	7.59e-41	-	-	-	-	-	-	-	-
KHOLCCEP_01349	1.19e-52	-	-	-	-	-	-	-	-
KHOLCCEP_01350	0.0	-	-	-	KL	-	-	-	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KHOLCCEP_01352	0.0	-	-	-	-	-	-	-	-
KHOLCCEP_01353	3.32e-224	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
KHOLCCEP_01354	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
KHOLCCEP_01355	3.57e-81	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
KHOLCCEP_01356	1.6e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
KHOLCCEP_01357	5.27e-69	-	-	-	-	-	-	-	-
KHOLCCEP_01358	1.78e-85	-	-	-	-	-	-	-	-
KHOLCCEP_01359	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase
KHOLCCEP_01360	7.79e-108	-	-	-	-	-	-	-	-
KHOLCCEP_01361	6.78e-79	-	-	-	-	-	-	-	-
KHOLCCEP_01362	9.23e-73	-	-	-	-	-	-	-	-
KHOLCCEP_01363	3.78e-290	-	-	-	S	-	-	-	HipA-like C-terminal domain
KHOLCCEP_01364	1.21e-130	-	-	-	-	ko:K03646	-	ko00000,ko02000	-
KHOLCCEP_01365	3.98e-27	-	-	-	-	-	-	-	-
KHOLCCEP_01366	4.07e-39	-	-	-	L	-	-	-	DNA integration
KHOLCCEP_01367	5.32e-36	-	-	-	-	-	-	-	-
KHOLCCEP_01368	8.08e-184	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
KHOLCCEP_01369	0.0	intA	-	-	L	-	-	-	Phage integrase family
KHOLCCEP_01370	8.85e-264	-	-	-	E	-	-	-	Belongs to the peptidase S1B family
KHOLCCEP_01372	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHOLCCEP_01373	1.23e-110	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KHOLCCEP_01374	2.45e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
KHOLCCEP_01375	1.19e-234	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
KHOLCCEP_01376	2.71e-299	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
KHOLCCEP_01377	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
KHOLCCEP_01378	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
KHOLCCEP_01379	4.02e-22	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
KHOLCCEP_01380	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
KHOLCCEP_01381	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
KHOLCCEP_01382	1.99e-250	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHOLCCEP_01383	3.42e-158	-	-	-	-	-	-	-	-
KHOLCCEP_01384	7.43e-256	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KHOLCCEP_01385	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
KHOLCCEP_01386	2.06e-171	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
KHOLCCEP_01387	4.56e-142	-	-	-	-	-	-	-	-
KHOLCCEP_01388	1.86e-245	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KHOLCCEP_01389	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHOLCCEP_01390	3.68e-152	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHOLCCEP_01392	3.43e-113	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
KHOLCCEP_01393	7.71e-276	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHOLCCEP_01394	3.38e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
KHOLCCEP_01395	4.91e-104	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KHOLCCEP_01396	6.59e-124	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
KHOLCCEP_01397	5.62e-156	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHOLCCEP_01398	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
KHOLCCEP_01399	1e-173	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
KHOLCCEP_01400	3.08e-234	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHOLCCEP_01401	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHOLCCEP_01402	1.42e-156	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
KHOLCCEP_01403	9.47e-220	-	-	-	EG	-	-	-	EamA-like transporter family
KHOLCCEP_01404	2.5e-175	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KHOLCCEP_01405	3.59e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
KHOLCCEP_01406	2.16e-157	-	-	-	T	-	-	-	Histidine kinase
KHOLCCEP_01407	4.84e-153	-	-	-	T	-	-	-	Histidine kinase
KHOLCCEP_01408	6.09e-152	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
KHOLCCEP_01409	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
KHOLCCEP_01410	0.0	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
KHOLCCEP_01411	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
KHOLCCEP_01412	1.4e-303	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
KHOLCCEP_01413	8.3e-150	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHOLCCEP_01414	3.8e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHOLCCEP_01416	8.91e-249	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KHOLCCEP_01417	0.0	-	-	-	S	-	-	-	Esterase-like activity of phytase
KHOLCCEP_01418	5.83e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHOLCCEP_01419	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHOLCCEP_01420	9.4e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHOLCCEP_01421	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHOLCCEP_01423	1.33e-255	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
KHOLCCEP_01424	1.04e-289	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
KHOLCCEP_01425	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
KHOLCCEP_01426	1.91e-298	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHOLCCEP_01427	2.05e-177	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
KHOLCCEP_01428	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
KHOLCCEP_01429	6.39e-140	-	-	-	-	-	-	-	-
KHOLCCEP_01430	2.2e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
KHOLCCEP_01431	4.41e-150	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
KHOLCCEP_01432	7.5e-43	-	-	-	K	-	-	-	DNA-binding transcription factor activity
KHOLCCEP_01433	1.64e-90	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHOLCCEP_01434	9.82e-45	-	-	-	-	-	-	-	-
KHOLCCEP_01435	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
KHOLCCEP_01436	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHOLCCEP_01437	3.47e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
KHOLCCEP_01438	5.35e-307	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
KHOLCCEP_01439	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
KHOLCCEP_01440	0.0	-	-	-	S	-	-	-	Putative esterase
KHOLCCEP_01441	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
KHOLCCEP_01443	2.72e-208	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
KHOLCCEP_01444	6.85e-166	-	-	-	S	-	-	-	cobalamin synthesis protein
KHOLCCEP_01445	1.03e-60	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
KHOLCCEP_01446	4.85e-65	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHOLCCEP_01447	2.54e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
KHOLCCEP_01448	3.05e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
KHOLCCEP_01449	4.31e-31	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
KHOLCCEP_01450	2.79e-255	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
KHOLCCEP_01451	3.19e-198	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
KHOLCCEP_01452	9.29e-62	-	-	-	-	-	-	-	-
KHOLCCEP_01453	4.79e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
KHOLCCEP_01454	5.14e-291	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHOLCCEP_01455	5.14e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHOLCCEP_01456	1.18e-227	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
KHOLCCEP_01457	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHOLCCEP_01459	2.12e-59	-	-	-	S	ko:K06990	-	ko00000,ko04812	Memo-like protein
KHOLCCEP_01460	2.99e-289	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
KHOLCCEP_01461	6.44e-205	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KHOLCCEP_01462	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHOLCCEP_01463	1.45e-312	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
KHOLCCEP_01464	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHOLCCEP_01465	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
KHOLCCEP_01466	2.33e-130	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHOLCCEP_01467	3.27e-38	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KHOLCCEP_01468	2.57e-118	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHOLCCEP_01469	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
KHOLCCEP_01470	2.95e-284	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
KHOLCCEP_01471	1.83e-244	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
KHOLCCEP_01472	1.03e-141	-	-	-	-	-	-	-	-
KHOLCCEP_01473	1.75e-199	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
KHOLCCEP_01474	4.48e-228	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
KHOLCCEP_01475	3.68e-277	-	-	-	GK	-	-	-	ROK family
KHOLCCEP_01476	4.9e-264	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
KHOLCCEP_01477	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
KHOLCCEP_01478	6.83e-253	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHOLCCEP_01479	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
KHOLCCEP_01480	1.39e-179	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
KHOLCCEP_01481	0.0	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KHOLCCEP_01482	2.13e-151	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
KHOLCCEP_01483	3.65e-08	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
KHOLCCEP_01484	4.78e-119	-	-	-	-	-	-	-	-
KHOLCCEP_01485	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHOLCCEP_01486	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHOLCCEP_01487	2.6e-231	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
KHOLCCEP_01488	3.02e-227	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
KHOLCCEP_01489	1.32e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
KHOLCCEP_01490	6.71e-284	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
KHOLCCEP_01491	3.84e-189	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHOLCCEP_01492	1.2e-45	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
KHOLCCEP_01493	1.23e-227	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KHOLCCEP_01494	3.47e-208	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KHOLCCEP_01495	1.22e-307	-	-	-	V	-	-	-	MatE
KHOLCCEP_01497	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KHOLCCEP_01498	1.27e-181	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KHOLCCEP_01499	4.49e-258	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHOLCCEP_01500	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
KHOLCCEP_01501	7.72e-278	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHOLCCEP_01502	3.49e-270	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHOLCCEP_01503	1.93e-202	-	-	-	G	-	-	-	Fructosamine kinase
KHOLCCEP_01504	2.34e-215	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KHOLCCEP_01505	2.89e-199	-	-	-	S	-	-	-	PAC2 family
KHOLCCEP_01509	5.26e-141	-	-	-	-	-	-	-	-
KHOLCCEP_01510	4.45e-190	-	-	-	-	-	-	-	-
KHOLCCEP_01513	0.0	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHOLCCEP_01514	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHOLCCEP_01515	0.0	-	3.2.1.52	GH20	M	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
KHOLCCEP_01516	2.79e-176	yebC	-	-	K	-	-	-	transcriptional regulatory protein
KHOLCCEP_01517	2.64e-129	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KHOLCCEP_01519	2.6e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHOLCCEP_01520	6.91e-259	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHOLCCEP_01521	3.73e-72	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
KHOLCCEP_01522	1.12e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHOLCCEP_01523	8.17e-285	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KHOLCCEP_01524	1.92e-211	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KHOLCCEP_01525	1.1e-313	-	-	-	-	-	-	-	-
KHOLCCEP_01526	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
KHOLCCEP_01527	5.17e-56	-	-	-	-	-	-	-	-
KHOLCCEP_01528	1.15e-165	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KHOLCCEP_01529	9.44e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KHOLCCEP_01530	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
KHOLCCEP_01531	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KHOLCCEP_01532	1.86e-209	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KHOLCCEP_01533	3.18e-237	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHOLCCEP_01534	8.92e-144	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
KHOLCCEP_01535	1.2e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
KHOLCCEP_01536	1.07e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
KHOLCCEP_01537	2.22e-151	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHOLCCEP_01538	6.52e-222	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
KHOLCCEP_01539	2.78e-57	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
KHOLCCEP_01540	2.65e-180	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
KHOLCCEP_01541	2.88e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
KHOLCCEP_01542	5.64e-153	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KHOLCCEP_01543	2.84e-82	-	-	-	-	-	-	-	-
KHOLCCEP_01545	5.93e-183	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
KHOLCCEP_01546	1.11e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
KHOLCCEP_01547	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
KHOLCCEP_01548	3.7e-70	-	-	-	-	-	-	-	-
KHOLCCEP_01549	0.0	-	-	-	K	-	-	-	WYL domain
KHOLCCEP_01550	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KHOLCCEP_01552	8.73e-88	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
KHOLCCEP_01553	4.33e-185	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
KHOLCCEP_01554	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHOLCCEP_01555	6.72e-158	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KHOLCCEP_01556	1.23e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
KHOLCCEP_01557	3.77e-118	-	-	-	T	-	-	-	Domain of unknown function (DUF4234)
KHOLCCEP_01558	3.35e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KHOLCCEP_01559	1.95e-23	-	-	-	-	-	-	-	-
KHOLCCEP_01560	6.95e-63	tam	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
KHOLCCEP_01561	1.17e-54	-	-	-	K	-	-	-	Helix-turn-helix
KHOLCCEP_01562	8.45e-286	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
KHOLCCEP_01563	8.27e-86	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
KHOLCCEP_01564	1.13e-226	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KHOLCCEP_01565	8.76e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
KHOLCCEP_01566	3.14e-171	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
KHOLCCEP_01567	1.39e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
KHOLCCEP_01568	9.78e-312	-	-	-	V	-	-	-	MatE
KHOLCCEP_01569	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHOLCCEP_01570	1.25e-19	-	-	-	KLT	-	-	-	Protein tyrosine kinase
KHOLCCEP_01571	8.59e-24	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
KHOLCCEP_01572	7.62e-191	-	-	-	-	-	-	-	-
KHOLCCEP_01573	8.91e-248	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
KHOLCCEP_01574	7.77e-88	-	-	-	K	-	-	-	MerR family regulatory protein
KHOLCCEP_01575	7.11e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHOLCCEP_01576	1.01e-229	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHOLCCEP_01577	1.77e-200	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
KHOLCCEP_01578	3.99e-231	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
KHOLCCEP_01579	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHOLCCEP_01580	1.83e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
KHOLCCEP_01581	7.76e-234	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
KHOLCCEP_01582	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
KHOLCCEP_01584	1.16e-208	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
KHOLCCEP_01585	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHOLCCEP_01586	5.84e-129	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
KHOLCCEP_01587	3.32e-264	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KHOLCCEP_01588	1.62e-227	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KHOLCCEP_01589	1.18e-30	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	EamA-like transporter family
KHOLCCEP_01590	1.39e-94	-	-	-	E	-	-	-	Rard protein
KHOLCCEP_01591	6.33e-38	-	-	-	-	-	-	-	-
KHOLCCEP_01592	1.7e-236	-	-	-	L	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
KHOLCCEP_01594	1.39e-199	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
KHOLCCEP_01595	0.0	-	-	-	O	-	-	-	Subtilase family
KHOLCCEP_01596	0.0	-	-	-	L	-	-	-	helicase
KHOLCCEP_01597	1.41e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4391)
KHOLCCEP_01598	6.5e-304	mod	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
KHOLCCEP_01599	0.0	res	3.1.21.5	-	V	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
KHOLCCEP_01601	6.38e-52	-	-	-	S	-	-	-	AAA domain
KHOLCCEP_01602	2.68e-169	-	-	-	-	-	-	-	-
KHOLCCEP_01603	1.1e-106	-	-	-	L	ko:K07485	-	ko00000	Transposase
KHOLCCEP_01604	7.24e-106	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
KHOLCCEP_01605	1.9e-137	-	-	-	L	-	-	-	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KHOLCCEP_01606	2.5e-39	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
KHOLCCEP_01607	1.9e-98	-	-	-	S	-	-	-	GIY-YIG catalytic domain
KHOLCCEP_01611	1.5e-15	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
KHOLCCEP_01614	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KHOLCCEP_01615	9.65e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
KHOLCCEP_01616	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHOLCCEP_01617	1.7e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
KHOLCCEP_01618	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
KHOLCCEP_01619	5.09e-243	-	-	-	V	-	-	-	N-Acetylmuramoyl-L-alanine amidase
KHOLCCEP_01620	3.43e-194	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_01621	5.63e-253	-	-	-	-	-	-	-	-
KHOLCCEP_01622	6.64e-296	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
KHOLCCEP_01623	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
KHOLCCEP_01624	5.85e-263	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHOLCCEP_01625	0.0	-	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHOLCCEP_01626	1.01e-275	-	-	-	I	ko:K13663	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
KHOLCCEP_01628	2.58e-165	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KHOLCCEP_01629	1.21e-252	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
KHOLCCEP_01630	1.4e-193	-	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
KHOLCCEP_01631	1.97e-186	rfbB2	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KHOLCCEP_01632	1.24e-124	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
KHOLCCEP_01633	3.48e-146	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHOLCCEP_01634	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHOLCCEP_01635	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
KHOLCCEP_01636	2.04e-194	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
KHOLCCEP_01637	7.41e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHOLCCEP_01638	6.75e-132	-	-	-	D	-	-	-	Septum formation initiator
KHOLCCEP_01639	6.25e-138	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
KHOLCCEP_01640	1.02e-234	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
KHOLCCEP_01642	2.65e-127	-	-	-	-	-	-	-	-
KHOLCCEP_01643	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
KHOLCCEP_01644	8.53e-95	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
KHOLCCEP_01645	1.67e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHOLCCEP_01648	4.58e-140	-	-	-	-	-	-	-	-
KHOLCCEP_01649	2.77e-193	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
KHOLCCEP_01650	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHOLCCEP_01651	2.73e-60	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KHOLCCEP_01652	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
KHOLCCEP_01653	0.0	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
KHOLCCEP_01654	2.82e-72	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KHOLCCEP_01655	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
KHOLCCEP_01656	0.0	-	-	-	-	-	-	-	-
KHOLCCEP_01657	7.03e-83	-	-	-	S	-	-	-	Zincin-like metallopeptidase
KHOLCCEP_01658	3.31e-200	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
KHOLCCEP_01659	4.15e-171	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
KHOLCCEP_01660	3.2e-93	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
KHOLCCEP_01661	2.06e-259	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHOLCCEP_01662	9.32e-164	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
KHOLCCEP_01663	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHOLCCEP_01664	1.99e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
KHOLCCEP_01665	8.3e-110	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KHOLCCEP_01666	2.15e-177	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
KHOLCCEP_01667	1.15e-209	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_01668	1.97e-230	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
KHOLCCEP_01669	4.22e-211	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHOLCCEP_01670	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
KHOLCCEP_01671	2.24e-139	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHOLCCEP_01672	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHOLCCEP_01673	3.96e-228	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
KHOLCCEP_01674	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
KHOLCCEP_01675	6.68e-140	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
KHOLCCEP_01677	5.44e-161	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
KHOLCCEP_01678	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHOLCCEP_01679	1.48e-218	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
KHOLCCEP_01680	2.36e-161	-	-	-	L	-	-	-	NUDIX domain
KHOLCCEP_01681	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
KHOLCCEP_01682	1.52e-138	-	-	-	-	-	-	-	-
KHOLCCEP_01683	1.94e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
KHOLCCEP_01685	6.28e-156	-	-	-	L	-	-	-	Phage integrase family
KHOLCCEP_01686	9.85e-140	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
KHOLCCEP_01687	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KHOLCCEP_01688	4.64e-295	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHOLCCEP_01689	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
KHOLCCEP_01690	4.04e-69	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
KHOLCCEP_01691	5.05e-129	-	-	-	L	-	-	-	AAA ATPase domain
KHOLCCEP_01692	1.47e-54	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD/REP helicase N-terminal domain
KHOLCCEP_01693	1.46e-37	-	-	-	-	-	-	-	-
KHOLCCEP_01694	0.000389	-	-	-	-	-	-	-	-
KHOLCCEP_01695	2.62e-13	-	-	-	-	-	-	-	-
KHOLCCEP_01696	3.81e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
KHOLCCEP_01697	4.36e-237	-	-	-	S	-	-	-	Protein of unknown function DUF262
KHOLCCEP_01699	6.93e-87	-	-	-	L	-	-	-	Integrase core domain
KHOLCCEP_01700	5.06e-46	-	-	-	L	-	-	-	Transposase
KHOLCCEP_01701	6.03e-232	-	-	-	-	-	-	-	-
KHOLCCEP_01702	1.53e-33	-	-	-	-	-	-	-	-
KHOLCCEP_01703	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
KHOLCCEP_01704	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KHOLCCEP_01705	7.55e-243	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
KHOLCCEP_01706	4.91e-150	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
KHOLCCEP_01707	6.55e-155	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
KHOLCCEP_01708	1.45e-298	-	-	-	T	-	-	-	Histidine kinase
KHOLCCEP_01709	1.06e-57	pacL	3.6.3.8, 3.6.3.9	-	P	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	ko00000,ko00001,ko01000,ko04147	ATPase, P-type transporting, HAD superfamily, subfamily IC
KHOLCCEP_01711	0.0	-	3.2.1.8, 3.5.1.104	-	G	ko:K01181,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
KHOLCCEP_01712	1.25e-252	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
KHOLCCEP_01713	5.35e-82	-	-	-	S	-	-	-	AAA ATPase domain
KHOLCCEP_01715	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHOLCCEP_01716	1.24e-210	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHOLCCEP_01717	3.1e-80	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHOLCCEP_01718	1.28e-252	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KHOLCCEP_01719	1.74e-96	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
KHOLCCEP_01720	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
KHOLCCEP_01721	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
KHOLCCEP_01722	6.15e-261	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHOLCCEP_01723	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHOLCCEP_01724	9.44e-234	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
KHOLCCEP_01725	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
KHOLCCEP_01726	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
KHOLCCEP_01727	7.06e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
KHOLCCEP_01728	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
KHOLCCEP_01729	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KHOLCCEP_01730	2.21e-109	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHOLCCEP_01731	5.48e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHOLCCEP_01732	4.44e-51	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KHOLCCEP_01733	7.96e-127	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
KHOLCCEP_01734	2.54e-191	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
KHOLCCEP_01735	7.13e-56	-	-	-	O	-	-	-	Glutaredoxin
KHOLCCEP_01736	3.93e-86	-	-	-	S	-	-	-	AIPR protein
KHOLCCEP_01737	1.48e-111	-	-	-	L	ko:K07485	-	ko00000	Transposase
KHOLCCEP_01739	0.0	-	-	-	S	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KHOLCCEP_01740	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
KHOLCCEP_01741	1.29e-191	-	-	-	L	ko:K07454	-	ko00000	HNH endonuclease
KHOLCCEP_01742	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
KHOLCCEP_01743	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KHOLCCEP_01744	1.56e-37	-	-	-	IQ	-	-	-	[acyl-carrier-protein] S-malonyltransferase activity
KHOLCCEP_01745	3.19e-145	-	-	-	K	-	-	-	WHG domain
KHOLCCEP_01746	7.44e-145	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
KHOLCCEP_01748	1.66e-69	-	-	-	-	-	-	-	-
KHOLCCEP_01749	2.21e-41	-	-	-	M	-	-	-	F5/8 type C domain
KHOLCCEP_01750	3.64e-243	-	-	-	C	-	-	-	Aldo/keto reductase family
KHOLCCEP_01751	7.47e-123	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KHOLCCEP_01752	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KHOLCCEP_01753	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
KHOLCCEP_01754	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
KHOLCCEP_01755	3.03e-139	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
KHOLCCEP_01756	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
KHOLCCEP_01757	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
KHOLCCEP_01758	1.11e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
KHOLCCEP_01759	1.24e-126	-	-	-	S	-	-	-	GtrA-like protein
KHOLCCEP_01760	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KHOLCCEP_01761	1.3e-160	-	-	-	G	-	-	-	Phosphoglycerate mutase family
KHOLCCEP_01762	8.38e-193	-	-	-	-	-	-	-	-
KHOLCCEP_01763	4.99e-179	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
KHOLCCEP_01764	5.05e-258	-	-	-	P	-	-	-	NMT1/THI5 like
KHOLCCEP_01765	1.3e-156	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
KHOLCCEP_01767	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHOLCCEP_01768	2.41e-113	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
KHOLCCEP_01769	1.09e-84	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
KHOLCCEP_01772	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KHOLCCEP_01773	1.12e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
KHOLCCEP_01774	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHOLCCEP_01775	3.31e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHOLCCEP_01776	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
KHOLCCEP_01778	1.74e-251	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KHOLCCEP_01779	3.04e-280	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
KHOLCCEP_01780	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHOLCCEP_01781	2.55e-289	-	-	-	G	-	-	-	Transmembrane secretion effector
KHOLCCEP_01782	9.78e-169	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KHOLCCEP_01783	3.77e-185	-	-	-	-	-	-	-	-
KHOLCCEP_01784	1.43e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHOLCCEP_01785	1.23e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHOLCCEP_01786	6.26e-223	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
KHOLCCEP_01787	1.71e-241	-	-	-	-	-	-	-	-
KHOLCCEP_01788	8.35e-232	-	-	-	-	-	-	-	-
KHOLCCEP_01789	1.03e-213	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
KHOLCCEP_01790	5.52e-152	-	-	-	S	-	-	-	CYTH
KHOLCCEP_01792	4.87e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
KHOLCCEP_01793	1.17e-25	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	carboxylic acid catabolic process
KHOLCCEP_01794	7.15e-50	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
KHOLCCEP_01795	5.97e-196	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
KHOLCCEP_01798	2.84e-08	-	-	-	L	-	-	-	PFAM Integrase catalytic
KHOLCCEP_01799	7.82e-240	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHOLCCEP_01800	1.47e-143	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
KHOLCCEP_01801	6.24e-200	-	-	-	S	ko:K11206	-	ko00000,ko01000	Carbon-nitrogen hydrolase
KHOLCCEP_01802	8.1e-232	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
KHOLCCEP_01803	1.01e-313	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
KHOLCCEP_01804	5.23e-107	-	-	-	-	-	-	-	-
KHOLCCEP_01805	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KHOLCCEP_01806	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
KHOLCCEP_01807	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
KHOLCCEP_01808	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K10907,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
KHOLCCEP_01809	4.95e-18	-	-	-	S	ko:K07149	-	ko00000	Membrane
KHOLCCEP_01810	2.22e-310	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
KHOLCCEP_01811	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHOLCCEP_01812	3.91e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
KHOLCCEP_01813	6.58e-175	-	-	-	S	-	-	-	UPF0126 domain
KHOLCCEP_01814	9.34e-141	-	-	-	T	-	-	-	RNA ligase
KHOLCCEP_01815	1.58e-287	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
KHOLCCEP_01816	2.74e-123	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KHOLCCEP_01817	4.21e-242	-	-	-	S	ko:K06889	-	ko00000	alpha beta
KHOLCCEP_01818	5.74e-305	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KHOLCCEP_01819	1.08e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
KHOLCCEP_01820	6.9e-259	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
KHOLCCEP_01821	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
KHOLCCEP_01822	5.62e-236	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHOLCCEP_01823	0.0	corC	-	-	S	-	-	-	CBS domain
KHOLCCEP_01824	1.82e-130	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHOLCCEP_01825	4.28e-253	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
KHOLCCEP_01826	1.37e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
KHOLCCEP_01827	2.18e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KHOLCCEP_01829	1.78e-208	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
KHOLCCEP_01830	1.42e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHOLCCEP_01831	7.04e-139	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KHOLCCEP_01832	4.14e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
KHOLCCEP_01833	2.09e-305	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHOLCCEP_01834	2.13e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
KHOLCCEP_01835	8.37e-298	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
KHOLCCEP_01836	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
KHOLCCEP_01837	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHOLCCEP_01838	3.21e-05	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
KHOLCCEP_01839	8e-154	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
KHOLCCEP_01840	9.43e-24	-	-	-	-	-	-	-	-
KHOLCCEP_01841	1.87e-102	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
KHOLCCEP_01842	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHOLCCEP_01843	1.57e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHOLCCEP_01844	3.73e-69	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
KHOLCCEP_01845	1.41e-250	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHOLCCEP_01846	6.58e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHOLCCEP_01847	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHOLCCEP_01848	7.33e-50	-	-	-	-	-	-	-	-
KHOLCCEP_01849	4.03e-85	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
KHOLCCEP_01850	3.08e-173	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
KHOLCCEP_01851	0.0	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
KHOLCCEP_01852	1.83e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHOLCCEP_01853	2.33e-173	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
KHOLCCEP_01854	1.87e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KHOLCCEP_01855	2.46e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
KHOLCCEP_01856	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KHOLCCEP_01857	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
KHOLCCEP_01858	2.66e-138	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHOLCCEP_01859	2.04e-308	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
KHOLCCEP_01861	5.26e-17	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHOLCCEP_01862	1.89e-21	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHOLCCEP_01863	2.14e-117	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHOLCCEP_01865	1.71e-144	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
KHOLCCEP_01866	9.3e-53	-	-	-	-	-	-	-	-
KHOLCCEP_01867	5.58e-33	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
KHOLCCEP_01868	8.39e-151	tnp3521a2	-	-	L	-	-	-	Integrase core domain
KHOLCCEP_01869	2.58e-63	-	-	-	L	ko:K07483	-	ko00000	Transposase
KHOLCCEP_01870	1.2e-83	-	-	-	D	-	-	-	MobA/MobL family
KHOLCCEP_01871	4.95e-85	-	-	-	-	-	-	-	-
KHOLCCEP_01873	4e-102	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family