ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LFDEFCAG_00001 0.0 - - - Q - - - AMP-binding enzyme
LFDEFCAG_00002 1.09e-86 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LFDEFCAG_00005 5.71e-189 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
LFDEFCAG_00006 1.71e-139 ypcB - - S - - - integral membrane protein
LFDEFCAG_00007 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LFDEFCAG_00008 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LFDEFCAG_00009 3.28e-233 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LFDEFCAG_00010 6.88e-230 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LFDEFCAG_00011 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
LFDEFCAG_00012 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LFDEFCAG_00013 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
LFDEFCAG_00014 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LFDEFCAG_00016 4.11e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LFDEFCAG_00018 1.7e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LFDEFCAG_00019 2.26e-95 - - - S - - - SnoaL-like domain
LFDEFCAG_00020 3.2e-254 - - - M - - - Glycosyltransferase, group 2 family protein
LFDEFCAG_00021 1.65e-265 mccF - - V - - - LD-carboxypeptidase
LFDEFCAG_00022 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
LFDEFCAG_00023 7.12e-311 - - - M ko:K07273 - ko00000 hydrolase, family 25
LFDEFCAG_00024 1.44e-234 - - - V - - - LD-carboxypeptidase
LFDEFCAG_00025 1.99e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
LFDEFCAG_00026 3.99e-158 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LFDEFCAG_00027 1.37e-248 - - - - - - - -
LFDEFCAG_00028 1.5e-186 - - - S - - - hydrolase activity, acting on ester bonds
LFDEFCAG_00029 1.47e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
LFDEFCAG_00030 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
LFDEFCAG_00031 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
LFDEFCAG_00032 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LFDEFCAG_00033 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LFDEFCAG_00034 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LFDEFCAG_00035 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LFDEFCAG_00036 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
LFDEFCAG_00037 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LFDEFCAG_00038 0.0 - - - S - - - Bacterial membrane protein, YfhO
LFDEFCAG_00039 2.01e-145 - - - G - - - Phosphoglycerate mutase family
LFDEFCAG_00040 6.38e-92 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LFDEFCAG_00042 2.24e-167 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
LFDEFCAG_00043 9.93e-91 - - - S - - - LuxR family transcriptional regulator
LFDEFCAG_00044 1.19e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
LFDEFCAG_00045 1.87e-117 - - - F - - - NUDIX domain
LFDEFCAG_00046 6.19e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_00047 9.28e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LFDEFCAG_00048 0.0 FbpA - - K - - - Fibronectin-binding protein
LFDEFCAG_00049 1.97e-87 - - - K - - - Transcriptional regulator
LFDEFCAG_00050 1.11e-205 - - - S - - - EDD domain protein, DegV family
LFDEFCAG_00051 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
LFDEFCAG_00052 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
LFDEFCAG_00053 3.03e-40 - - - - - - - -
LFDEFCAG_00054 2.37e-65 - - - - - - - -
LFDEFCAG_00055 4.87e-191 - - - C - - - Domain of unknown function (DUF4931)
LFDEFCAG_00056 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
LFDEFCAG_00058 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
LFDEFCAG_00059 2.98e-166 yejC - - S - - - Protein of unknown function (DUF1003)
LFDEFCAG_00060 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
LFDEFCAG_00061 4.31e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LFDEFCAG_00062 9.54e-175 - - - - - - - -
LFDEFCAG_00063 7.79e-78 - - - - - - - -
LFDEFCAG_00064 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LFDEFCAG_00065 7.87e-289 - - - - - - - -
LFDEFCAG_00066 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
LFDEFCAG_00067 1.47e-243 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
LFDEFCAG_00068 4.09e-250 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LFDEFCAG_00069 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LFDEFCAG_00070 7.77e-120 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LFDEFCAG_00071 5.38e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LFDEFCAG_00072 2.33e-288 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LFDEFCAG_00073 3.73e-71 - - - - - - - -
LFDEFCAG_00074 3.03e-313 - - - M - - - Glycosyl transferase family group 2
LFDEFCAG_00075 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFDEFCAG_00076 2.08e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
LFDEFCAG_00077 1.07e-43 - - - S - - - YozE SAM-like fold
LFDEFCAG_00078 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LFDEFCAG_00079 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LFDEFCAG_00080 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
LFDEFCAG_00081 3.82e-228 - - - K - - - Transcriptional regulator
LFDEFCAG_00082 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LFDEFCAG_00083 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LFDEFCAG_00084 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LFDEFCAG_00085 1.27e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LFDEFCAG_00086 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LFDEFCAG_00087 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LFDEFCAG_00088 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
LFDEFCAG_00089 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LFDEFCAG_00090 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LFDEFCAG_00091 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
LFDEFCAG_00092 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LFDEFCAG_00093 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LFDEFCAG_00095 7.29e-292 XK27_05470 - - E - - - Methionine synthase
LFDEFCAG_00096 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
LFDEFCAG_00097 5.85e-159 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
LFDEFCAG_00098 4.28e-253 XK27_00915 - - C - - - Luciferase-like monooxygenase
LFDEFCAG_00099 0.0 qacA - - EGP - - - Major Facilitator
LFDEFCAG_00100 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LFDEFCAG_00101 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
LFDEFCAG_00102 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
LFDEFCAG_00103 5.91e-209 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
LFDEFCAG_00104 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
LFDEFCAG_00105 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LFDEFCAG_00106 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LFDEFCAG_00107 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_00108 6.46e-109 - - - - - - - -
LFDEFCAG_00109 2.11e-290 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LFDEFCAG_00110 5.66e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LFDEFCAG_00111 1.29e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LFDEFCAG_00112 1.82e-278 XK27_05225 - - S - - - Tetratricopeptide repeat protein
LFDEFCAG_00113 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LFDEFCAG_00114 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LFDEFCAG_00115 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LFDEFCAG_00116 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LFDEFCAG_00117 1.25e-39 - - - M - - - Lysin motif
LFDEFCAG_00118 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LFDEFCAG_00119 5.38e-249 - - - S - - - Helix-turn-helix domain
LFDEFCAG_00120 9.13e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LFDEFCAG_00121 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LFDEFCAG_00122 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LFDEFCAG_00123 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LFDEFCAG_00124 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LFDEFCAG_00125 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
LFDEFCAG_00126 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
LFDEFCAG_00127 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
LFDEFCAG_00128 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LFDEFCAG_00129 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LFDEFCAG_00130 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LFDEFCAG_00131 7.03e-40 - - - S - - - Protein of unknown function (DUF2929)
LFDEFCAG_00132 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LFDEFCAG_00133 3.17e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LFDEFCAG_00134 1.61e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LFDEFCAG_00135 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LFDEFCAG_00136 2.89e-294 - - - M - - - O-Antigen ligase
LFDEFCAG_00137 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LFDEFCAG_00138 1.71e-212 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_00139 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LFDEFCAG_00140 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
LFDEFCAG_00141 1.94e-83 - - - P - - - Rhodanese Homology Domain
LFDEFCAG_00142 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
LFDEFCAG_00143 5.78e-268 - - - - - - - -
LFDEFCAG_00144 6.09e-281 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
LFDEFCAG_00145 1.51e-232 - - - C - - - Zinc-binding dehydrogenase
LFDEFCAG_00146 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
LFDEFCAG_00147 6.31e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LFDEFCAG_00148 1.54e-305 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
LFDEFCAG_00149 4.38e-102 - - - K - - - Transcriptional regulator
LFDEFCAG_00150 2.02e-268 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LFDEFCAG_00151 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LFDEFCAG_00152 4.14e-177 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LFDEFCAG_00153 1.25e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
LFDEFCAG_00154 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
LFDEFCAG_00155 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
LFDEFCAG_00156 5.7e-146 - - - GM - - - epimerase
LFDEFCAG_00157 0.0 - - - S - - - Zinc finger, swim domain protein
LFDEFCAG_00158 6.13e-105 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_00159 3.22e-273 - - - S - - - membrane
LFDEFCAG_00160 1.55e-07 - - - K - - - transcriptional regulator
LFDEFCAG_00162 8.13e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LFDEFCAG_00163 8.34e-36 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_00164 1.95e-250 - - - K - - - Transcriptional regulator
LFDEFCAG_00165 1.78e-47 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LFDEFCAG_00166 3.08e-26 - - - - - - - -
LFDEFCAG_00167 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LFDEFCAG_00168 1.92e-285 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
LFDEFCAG_00169 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LFDEFCAG_00170 1.76e-211 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
LFDEFCAG_00171 3.7e-199 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LFDEFCAG_00172 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LFDEFCAG_00173 7.17e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
LFDEFCAG_00174 8.5e-55 - - - - - - - -
LFDEFCAG_00175 6.97e-45 - - - - - - - -
LFDEFCAG_00176 7.12e-226 - - - - - - - -
LFDEFCAG_00177 2.06e-30 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
LFDEFCAG_00178 6.02e-137 CP_1020 - - S - - - zinc ion binding
LFDEFCAG_00180 1.8e-24 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
LFDEFCAG_00181 1.13e-257 - - - S - - - peptidoglycan catabolic process
LFDEFCAG_00182 2.77e-77 - - - - - - - -
LFDEFCAG_00183 2.54e-42 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LFDEFCAG_00184 5.09e-55 - - - - - - - -
LFDEFCAG_00185 3.72e-21 - - - - - - - -
LFDEFCAG_00187 5.08e-26 int3 - - L - - - Belongs to the 'phage' integrase family
LFDEFCAG_00188 3.22e-224 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
LFDEFCAG_00189 2.42e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LFDEFCAG_00190 3.66e-224 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
LFDEFCAG_00191 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LFDEFCAG_00192 1.52e-103 - - - - - - - -
LFDEFCAG_00193 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
LFDEFCAG_00194 1.61e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LFDEFCAG_00195 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
LFDEFCAG_00196 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LFDEFCAG_00197 0.0 sufI - - Q - - - Multicopper oxidase
LFDEFCAG_00198 7.16e-155 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LFDEFCAG_00199 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
LFDEFCAG_00200 8.95e-60 - - - - - - - -
LFDEFCAG_00201 9e-227 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LFDEFCAG_00202 4.08e-306 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LFDEFCAG_00203 0.0 - - - P - - - Major Facilitator Superfamily
LFDEFCAG_00204 2.24e-112 - - - K - - - Transcriptional regulator PadR-like family
LFDEFCAG_00205 3.93e-59 - - - - - - - -
LFDEFCAG_00206 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LFDEFCAG_00207 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LFDEFCAG_00208 1.1e-280 - - - - - - - -
LFDEFCAG_00209 2.25e-286 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LFDEFCAG_00210 1.14e-186 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LFDEFCAG_00211 4.45e-116 metP_2 - - U ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LFDEFCAG_00212 7.98e-158 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LFDEFCAG_00213 1.06e-143 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
LFDEFCAG_00214 1.45e-79 - - - S - - - CHY zinc finger
LFDEFCAG_00215 1.49e-227 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LFDEFCAG_00216 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LFDEFCAG_00217 6.4e-54 - - - - - - - -
LFDEFCAG_00218 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LFDEFCAG_00219 7.28e-42 - - - - - - - -
LFDEFCAG_00220 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
LFDEFCAG_00221 3.91e-304 xylP1 - - G - - - MFS/sugar transport protein
LFDEFCAG_00223 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
LFDEFCAG_00224 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
LFDEFCAG_00225 3.09e-243 - - - - - - - -
LFDEFCAG_00226 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_00227 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LFDEFCAG_00228 2.06e-30 - - - - - - - -
LFDEFCAG_00229 2.14e-117 - - - K - - - acetyltransferase
LFDEFCAG_00230 5.39e-111 - - - K - - - GNAT family
LFDEFCAG_00231 8.08e-110 - - - S - - - ASCH
LFDEFCAG_00232 4.3e-124 - - - K - - - Cupin domain
LFDEFCAG_00233 5.09e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LFDEFCAG_00234 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_00235 1.13e-180 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_00236 4.36e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_00237 9.25e-32 - - - U - - - Preprotein translocase subunit SecB
LFDEFCAG_00238 1.04e-35 - - - - - - - -
LFDEFCAG_00240 3.59e-48 - - - - - - - -
LFDEFCAG_00241 1.36e-287 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LFDEFCAG_00242 1.24e-99 - - - K - - - Transcriptional regulator
LFDEFCAG_00243 7.61e-102 - - - S ko:K02348 - ko00000 GNAT family
LFDEFCAG_00244 3.74e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LFDEFCAG_00245 2.03e-75 - - - - - - - -
LFDEFCAG_00246 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
LFDEFCAG_00247 2.8e-169 - - - - - - - -
LFDEFCAG_00248 2.59e-228 - - - - - - - -
LFDEFCAG_00249 1.71e-87 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
LFDEFCAG_00250 1.43e-82 - - - M - - - LysM domain protein
LFDEFCAG_00251 7.98e-80 - - - M - - - Lysin motif
LFDEFCAG_00252 4.75e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_00253 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_00254 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_00255 1.84e-295 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
LFDEFCAG_00256 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
LFDEFCAG_00257 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LFDEFCAG_00258 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
LFDEFCAG_00259 1.17e-135 - - - K - - - transcriptional regulator
LFDEFCAG_00260 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LFDEFCAG_00261 1.49e-63 - - - - - - - -
LFDEFCAG_00262 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
LFDEFCAG_00263 1.76e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LFDEFCAG_00264 2.87e-56 - - - - - - - -
LFDEFCAG_00265 6.77e-75 - - - - - - - -
LFDEFCAG_00266 1.81e-308 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_00267 1.61e-166 yidA - - K - - - Helix-turn-helix domain, rpiR family
LFDEFCAG_00268 2.42e-65 - - - - - - - -
LFDEFCAG_00269 3.28e-166 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
LFDEFCAG_00270 1.82e-316 hpk2 - - T - - - Histidine kinase
LFDEFCAG_00271 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
LFDEFCAG_00272 0.0 ydiC - - EGP - - - Major Facilitator
LFDEFCAG_00273 1.55e-55 - - - - - - - -
LFDEFCAG_00274 2.92e-57 - - - - - - - -
LFDEFCAG_00275 4.68e-152 - - - - - - - -
LFDEFCAG_00276 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LFDEFCAG_00277 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_00278 8.9e-96 ywnA - - K - - - Transcriptional regulator
LFDEFCAG_00279 7.84e-92 - - - - - - - -
LFDEFCAG_00280 1.78e-128 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LFDEFCAG_00281 2.13e-184 - - - - - - - -
LFDEFCAG_00282 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LFDEFCAG_00283 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LFDEFCAG_00284 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LFDEFCAG_00285 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LFDEFCAG_00286 6.35e-56 - - - - - - - -
LFDEFCAG_00287 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
LFDEFCAG_00288 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
LFDEFCAG_00289 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
LFDEFCAG_00290 1.3e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LFDEFCAG_00291 1e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LFDEFCAG_00292 7.42e-125 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
LFDEFCAG_00293 1.82e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
LFDEFCAG_00294 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
LFDEFCAG_00295 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
LFDEFCAG_00296 2.98e-90 - - - - - - - -
LFDEFCAG_00297 1.22e-125 - - - - - - - -
LFDEFCAG_00298 5.92e-67 - - - - - - - -
LFDEFCAG_00299 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LFDEFCAG_00300 1.21e-111 - - - - - - - -
LFDEFCAG_00301 1.06e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
LFDEFCAG_00302 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_00303 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
LFDEFCAG_00304 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LFDEFCAG_00305 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LFDEFCAG_00307 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LFDEFCAG_00308 2.32e-43 ygzD - - K ko:K07729 - ko00000,ko03000 Transcriptional
LFDEFCAG_00309 1.2e-91 - - - - - - - -
LFDEFCAG_00310 3.68e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LFDEFCAG_00311 2.16e-201 dkgB - - S - - - reductase
LFDEFCAG_00312 2.28e-114 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LFDEFCAG_00313 2.02e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
LFDEFCAG_00314 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LFDEFCAG_00315 8.68e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
LFDEFCAG_00316 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
LFDEFCAG_00317 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFDEFCAG_00318 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFDEFCAG_00319 3.81e-18 - - - - - - - -
LFDEFCAG_00320 3.69e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LFDEFCAG_00321 6.48e-210 fbpA - - K - - - Domain of unknown function (DUF814)
LFDEFCAG_00322 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
LFDEFCAG_00323 6.33e-46 - - - - - - - -
LFDEFCAG_00324 7.12e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
LFDEFCAG_00325 2.73e-147 pgm1 - - G - - - phosphoglycerate mutase
LFDEFCAG_00326 7.18e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LFDEFCAG_00327 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFDEFCAG_00328 3.22e-103 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LFDEFCAG_00329 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LFDEFCAG_00330 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LFDEFCAG_00331 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
LFDEFCAG_00333 0.0 - - - M - - - domain protein
LFDEFCAG_00334 3.95e-223 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LFDEFCAG_00335 9.49e-197 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
LFDEFCAG_00336 1.29e-143 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
LFDEFCAG_00337 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
LFDEFCAG_00338 4.34e-31 - - - - - - - -
LFDEFCAG_00339 2.01e-227 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_00340 1.53e-49 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_00341 6.14e-53 - - - - - - - -
LFDEFCAG_00342 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LFDEFCAG_00343 1.63e-45 - - - - - - - -
LFDEFCAG_00344 1.18e-217 - - - S - - - helicase activity
LFDEFCAG_00345 1.29e-52 - - - S - - - Siphovirus Gp157
LFDEFCAG_00346 5.15e-16 - - - - - - - -
LFDEFCAG_00347 6.53e-53 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LFDEFCAG_00348 3.41e-31 - - - K - - - helix_turn_helix, mercury resistance
LFDEFCAG_00349 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
LFDEFCAG_00350 1.91e-280 - - - S - - - Membrane
LFDEFCAG_00351 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
LFDEFCAG_00352 1.26e-137 yoaZ - - S - - - intracellular protease amidase
LFDEFCAG_00353 5.52e-55 - - - K - - - HxlR-like helix-turn-helix
LFDEFCAG_00354 2.7e-76 - - - - - - - -
LFDEFCAG_00355 2.06e-81 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_00356 5.31e-66 - - - K - - - Helix-turn-helix domain
LFDEFCAG_00357 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
LFDEFCAG_00358 5.19e-50 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
LFDEFCAG_00359 5.04e-92 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LFDEFCAG_00360 5.68e-155 yciB - - M - - - ErfK YbiS YcfS YnhG
LFDEFCAG_00361 4.01e-142 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
LFDEFCAG_00362 1.93e-139 - - - GM - - - NAD(P)H-binding
LFDEFCAG_00363 5.35e-102 - - - GM - - - SnoaL-like domain
LFDEFCAG_00364 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
LFDEFCAG_00365 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
LFDEFCAG_00366 7.9e-136 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_00367 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
LFDEFCAG_00368 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
LFDEFCAG_00370 6.79e-53 - - - - - - - -
LFDEFCAG_00371 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LFDEFCAG_00372 9.26e-233 ydbI - - K - - - AI-2E family transporter
LFDEFCAG_00373 7.62e-270 xylR - - GK - - - ROK family
LFDEFCAG_00374 6.04e-150 - - - - - - - -
LFDEFCAG_00375 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LFDEFCAG_00376 4.04e-211 - - - - - - - -
LFDEFCAG_00377 1.66e-259 pkn2 - - KLT - - - Protein tyrosine kinase
LFDEFCAG_00378 5.03e-37 - - - S - - - Protein of unknown function (DUF4064)
LFDEFCAG_00379 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
LFDEFCAG_00380 5.61e-98 - - - S - - - Psort location Cytoplasmic, score
LFDEFCAG_00381 2.12e-72 - - - - - - - -
LFDEFCAG_00382 9.65e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
LFDEFCAG_00383 5.93e-73 - - - S - - - branched-chain amino acid
LFDEFCAG_00384 2.05e-167 - - - E - - - branched-chain amino acid
LFDEFCAG_00385 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
LFDEFCAG_00386 3.61e-303 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LFDEFCAG_00387 5.61e-273 hpk31 - - T - - - Histidine kinase
LFDEFCAG_00388 1.14e-159 vanR - - K - - - response regulator
LFDEFCAG_00389 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
LFDEFCAG_00390 1.1e-206 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LFDEFCAG_00391 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LFDEFCAG_00392 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
LFDEFCAG_00393 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LFDEFCAG_00394 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
LFDEFCAG_00395 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LFDEFCAG_00396 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
LFDEFCAG_00397 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LFDEFCAG_00398 1.81e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
LFDEFCAG_00399 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
LFDEFCAG_00400 3.45e-198 - - - S - - - Bacterial membrane protein, YfhO
LFDEFCAG_00401 1.23e-187 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LFDEFCAG_00402 3.36e-216 - - - K - - - LysR substrate binding domain
LFDEFCAG_00403 2.07e-302 - - - EK - - - Aminotransferase, class I
LFDEFCAG_00404 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LFDEFCAG_00405 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_00406 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_00407 7.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LFDEFCAG_00408 1.07e-127 - - - KT - - - response to antibiotic
LFDEFCAG_00409 8.52e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
LFDEFCAG_00410 2.1e-133 - - - S - - - Protein of unknown function (DUF1700)
LFDEFCAG_00411 1.37e-201 - - - S - - - Putative adhesin
LFDEFCAG_00412 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LFDEFCAG_00413 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LFDEFCAG_00414 1.57e-234 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
LFDEFCAG_00415 7.52e-263 - - - S - - - DUF218 domain
LFDEFCAG_00416 2.44e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
LFDEFCAG_00417 3.56e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_00418 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LFDEFCAG_00419 6.26e-101 - - - - - - - -
LFDEFCAG_00420 4.17e-263 - 4.1.1.45 - E ko:K03392,ko:K07045 ko00380,ko01100,map00380,map01100 ko00000,ko00001,ko00002,ko01000 amidohydrolase
LFDEFCAG_00421 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LFDEFCAG_00422 2.01e-307 - - - S - - - Neutral/alkaline non-lysosomal ceramidase, N-terminal
LFDEFCAG_00423 6.36e-297 - - - - - - - -
LFDEFCAG_00424 3.91e-211 - - - K - - - LysR substrate binding domain
LFDEFCAG_00425 1.9e-194 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
LFDEFCAG_00426 3.03e-191 - - - S - - - haloacid dehalogenase-like hydrolase
LFDEFCAG_00427 1.29e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LFDEFCAG_00428 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
LFDEFCAG_00429 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
LFDEFCAG_00430 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LFDEFCAG_00431 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
LFDEFCAG_00432 2.11e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LFDEFCAG_00433 4.08e-101 - - - K - - - MerR family regulatory protein
LFDEFCAG_00434 8.79e-199 - - - GM - - - NmrA-like family
LFDEFCAG_00435 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LFDEFCAG_00436 1.25e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
LFDEFCAG_00438 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
LFDEFCAG_00439 8.44e-304 - - - S - - - module of peptide synthetase
LFDEFCAG_00440 3.32e-135 - - - - - - - -
LFDEFCAG_00441 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LFDEFCAG_00442 1.28e-77 - - - S - - - Enterocin A Immunity
LFDEFCAG_00443 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
LFDEFCAG_00444 3.23e-216 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
LFDEFCAG_00445 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
LFDEFCAG_00446 2.4e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
LFDEFCAG_00447 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
LFDEFCAG_00448 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
LFDEFCAG_00449 1.03e-34 - - - - - - - -
LFDEFCAG_00450 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
LFDEFCAG_00451 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
LFDEFCAG_00452 1.04e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
LFDEFCAG_00453 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
LFDEFCAG_00454 1.22e-252 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LFDEFCAG_00455 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LFDEFCAG_00456 2.49e-73 - - - S - - - Enterocin A Immunity
LFDEFCAG_00457 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LFDEFCAG_00458 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LFDEFCAG_00459 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LFDEFCAG_00460 1.45e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LFDEFCAG_00461 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LFDEFCAG_00463 1.88e-106 - - - - - - - -
LFDEFCAG_00464 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
LFDEFCAG_00466 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LFDEFCAG_00467 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LFDEFCAG_00468 1.54e-228 ydbI - - K - - - AI-2E family transporter
LFDEFCAG_00469 1.01e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
LFDEFCAG_00470 3.3e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LFDEFCAG_00471 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LFDEFCAG_00472 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
LFDEFCAG_00473 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
LFDEFCAG_00474 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
LFDEFCAG_00475 8.03e-28 - - - - - - - -
LFDEFCAG_00476 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LFDEFCAG_00477 3.94e-271 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
LFDEFCAG_00478 6.2e-131 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
LFDEFCAG_00479 9.16e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LFDEFCAG_00480 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
LFDEFCAG_00481 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
LFDEFCAG_00482 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LFDEFCAG_00483 1.73e-108 cvpA - - S - - - Colicin V production protein
LFDEFCAG_00484 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LFDEFCAG_00485 4.41e-316 - - - EGP - - - Major Facilitator
LFDEFCAG_00487 4.54e-54 - - - - - - - -
LFDEFCAG_00488 3e-44 - - - L - - - Integrase
LFDEFCAG_00489 1.4e-164 epsB - - M - - - biosynthesis protein
LFDEFCAG_00490 4.78e-163 ywqD - - D - - - Capsular exopolysaccharide family
LFDEFCAG_00491 1.37e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LFDEFCAG_00492 5.11e-186 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LFDEFCAG_00494 9.5e-200 - - - K - - - helix_turn_helix, arabinose operon control protein
LFDEFCAG_00495 9.59e-156 - - - L - - - Psort location Cytoplasmic, score
LFDEFCAG_00496 1.1e-110 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LFDEFCAG_00498 3.68e-186 - - - L - - - Transposase and inactivated derivatives, IS30 family
LFDEFCAG_00499 3.19e-50 - - - - - - - -
LFDEFCAG_00500 4.05e-53 - - - - - - - -
LFDEFCAG_00501 1.26e-151 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LFDEFCAG_00502 2.24e-262 - - - EGP - - - Transporter, major facilitator family protein
LFDEFCAG_00503 3.41e-187 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LFDEFCAG_00504 1.12e-210 - - - K - - - Transcriptional regulator
LFDEFCAG_00505 8.38e-192 - - - S - - - hydrolase
LFDEFCAG_00506 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LFDEFCAG_00507 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LFDEFCAG_00509 1.15e-43 - - - - - - - -
LFDEFCAG_00510 6.24e-25 plnR - - - - - - -
LFDEFCAG_00511 1.62e-151 - - - - - - - -
LFDEFCAG_00512 8.73e-27 plnJ - - - - - - -
LFDEFCAG_00513 3.36e-38 - - - - - - - -
LFDEFCAG_00515 5.58e-291 - - - M - - - Glycosyl transferase family 2
LFDEFCAG_00516 2.83e-158 plnP - - S - - - CAAX protease self-immunity
LFDEFCAG_00518 1.07e-140 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LFDEFCAG_00519 1.96e-169 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LFDEFCAG_00520 8.15e-167 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_00521 1.93e-31 plnF - - - - - - -
LFDEFCAG_00522 8.82e-32 - - - - - - - -
LFDEFCAG_00523 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LFDEFCAG_00524 1.3e-109 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
LFDEFCAG_00525 1.99e-181 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
LFDEFCAG_00526 1.5e-139 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_00527 9.11e-25 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_00528 5.71e-89 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_00529 2.75e-145 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_00530 7.78e-126 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_00531 5.5e-42 - - - - - - - -
LFDEFCAG_00532 0.0 - - - L - - - DNA helicase
LFDEFCAG_00533 3.54e-182 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
LFDEFCAG_00534 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LFDEFCAG_00535 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
LFDEFCAG_00536 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_00537 9.68e-34 - - - - - - - -
LFDEFCAG_00538 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
LFDEFCAG_00539 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_00540 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LFDEFCAG_00541 6.97e-209 - - - GK - - - ROK family
LFDEFCAG_00542 1.14e-173 yecA - - K - - - Helix-turn-helix domain, rpiR family
LFDEFCAG_00543 4.17e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LFDEFCAG_00544 4.28e-263 - - - - - - - -
LFDEFCAG_00545 4.17e-193 - - - S - - - Psort location Cytoplasmic, score
LFDEFCAG_00546 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LFDEFCAG_00547 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
LFDEFCAG_00548 4.65e-229 - - - - - - - -
LFDEFCAG_00549 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
LFDEFCAG_00550 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
LFDEFCAG_00551 1.14e-92 - - - F - - - DNA mismatch repair protein MutT
LFDEFCAG_00552 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LFDEFCAG_00553 4.08e-270 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
LFDEFCAG_00554 7.76e-186 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
LFDEFCAG_00555 1.32e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LFDEFCAG_00556 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LFDEFCAG_00557 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
LFDEFCAG_00558 2.26e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LFDEFCAG_00559 1.56e-229 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
LFDEFCAG_00560 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LFDEFCAG_00561 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LFDEFCAG_00562 3.71e-15 - - - T ko:K21493 - ko00000,ko01000,ko02048 Pre-toxin TG
LFDEFCAG_00563 2.95e-57 - - - S - - - ankyrin repeats
LFDEFCAG_00564 1.78e-47 - - - - - - - -
LFDEFCAG_00565 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LFDEFCAG_00566 9.41e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LFDEFCAG_00567 1.15e-195 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
LFDEFCAG_00568 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LFDEFCAG_00569 1.82e-232 - - - S - - - DUF218 domain
LFDEFCAG_00570 7.12e-178 - - - - - - - -
LFDEFCAG_00571 4.85e-190 yxeH - - S - - - hydrolase
LFDEFCAG_00572 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
LFDEFCAG_00573 8.97e-200 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
LFDEFCAG_00574 1.66e-100 ywiB - - S - - - Domain of unknown function (DUF1934)
LFDEFCAG_00575 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LFDEFCAG_00576 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LFDEFCAG_00577 5.84e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LFDEFCAG_00578 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
LFDEFCAG_00579 1.52e-158 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
LFDEFCAG_00580 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LFDEFCAG_00581 6.59e-170 - - - S - - - YheO-like PAS domain
LFDEFCAG_00582 4.01e-36 - - - - - - - -
LFDEFCAG_00583 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LFDEFCAG_00584 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LFDEFCAG_00585 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LFDEFCAG_00586 2.57e-274 - - - J - - - translation release factor activity
LFDEFCAG_00587 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
LFDEFCAG_00588 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
LFDEFCAG_00589 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LFDEFCAG_00590 1.84e-189 - - - - - - - -
LFDEFCAG_00591 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LFDEFCAG_00592 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LFDEFCAG_00593 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LFDEFCAG_00594 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LFDEFCAG_00595 4.28e-84 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LFDEFCAG_00596 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LFDEFCAG_00597 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LFDEFCAG_00598 9.1e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LFDEFCAG_00599 1.04e-243 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LFDEFCAG_00600 3.39e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LFDEFCAG_00601 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LFDEFCAG_00602 4.66e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
LFDEFCAG_00603 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LFDEFCAG_00604 1.3e-110 queT - - S - - - QueT transporter
LFDEFCAG_00605 4.87e-148 - - - S - - - (CBS) domain
LFDEFCAG_00606 0.0 - - - S - - - Putative peptidoglycan binding domain
LFDEFCAG_00607 1.13e-225 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LFDEFCAG_00608 8.29e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LFDEFCAG_00609 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LFDEFCAG_00610 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LFDEFCAG_00611 7.72e-57 yabO - - J - - - S4 domain protein
LFDEFCAG_00613 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LFDEFCAG_00614 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
LFDEFCAG_00615 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LFDEFCAG_00616 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LFDEFCAG_00617 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LFDEFCAG_00618 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LFDEFCAG_00619 2.17e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LFDEFCAG_00620 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LFDEFCAG_00621 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LFDEFCAG_00623 5.18e-186 srlD 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
LFDEFCAG_00624 2.04e-109 - - - L ko:K07474 - ko00000 Terminase small subunit
LFDEFCAG_00625 1.38e-248 - - - S - - - Terminase-like family
LFDEFCAG_00626 2.73e-24 - - - - - - - -
LFDEFCAG_00627 1.98e-41 - - - S - - - zinc-ribbon domain
LFDEFCAG_00628 5.85e-132 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LFDEFCAG_00629 4.71e-119 srlM1 - - K - - - Glucitol operon activator protein (GutM)
LFDEFCAG_00630 1.88e-131 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
LFDEFCAG_00631 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
LFDEFCAG_00632 6.29e-141 - - - S - - - Protein of unknown function, DUF488
LFDEFCAG_00633 1.91e-46 - - - S - - - Protein of unknown function (DUF2945)
LFDEFCAG_00634 3.36e-60 - - - P ko:K05524,ko:K06886 - ko00000 Tellurite resistance protein tehB
LFDEFCAG_00635 1.17e-88 - - - S - - - Protein of unknown function, DUF488
LFDEFCAG_00636 0.0 norB 1.7.2.5 - P ko:K04561 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the heme-copper respiratory oxidase family
LFDEFCAG_00637 5.98e-302 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
LFDEFCAG_00638 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LFDEFCAG_00639 1.39e-233 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
LFDEFCAG_00640 1.4e-162 - - - S - - - DJ-1/PfpI family
LFDEFCAG_00641 7.65e-121 yfbM - - K - - - FR47-like protein
LFDEFCAG_00642 1.56e-197 - - - EG - - - EamA-like transporter family
LFDEFCAG_00643 2.81e-164 - - - S - - - Protein of unknown function
LFDEFCAG_00644 0.0 fusA1 - - J - - - elongation factor G
LFDEFCAG_00645 3.3e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LFDEFCAG_00646 6.07e-223 - - - K - - - WYL domain
LFDEFCAG_00647 3.06e-165 - - - F - - - glutamine amidotransferase
LFDEFCAG_00648 1.65e-106 - - - S - - - ASCH
LFDEFCAG_00649 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
LFDEFCAG_00650 6.86e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LFDEFCAG_00651 0.0 - - - S - - - Putative threonine/serine exporter
LFDEFCAG_00652 2.28e-250 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LFDEFCAG_00653 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LFDEFCAG_00655 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
LFDEFCAG_00656 5.07e-157 ydgI - - C - - - Nitroreductase family
LFDEFCAG_00657 2.34e-203 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
LFDEFCAG_00658 4.06e-211 - - - S - - - KR domain
LFDEFCAG_00659 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LFDEFCAG_00660 2.49e-95 - - - C - - - FMN binding
LFDEFCAG_00661 1.46e-204 - - - K - - - LysR family
LFDEFCAG_00662 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LFDEFCAG_00663 0.0 - - - C - - - FMN_bind
LFDEFCAG_00664 9.9e-203 - - - S - - - Protein of unknown function (DUF2785)
LFDEFCAG_00665 1.57e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
LFDEFCAG_00666 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
LFDEFCAG_00667 8.12e-158 pnb - - C - - - nitroreductase
LFDEFCAG_00668 3.46e-156 ung2 - - L - - - Uracil-DNA glycosylase
LFDEFCAG_00669 8.48e-215 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LFDEFCAG_00670 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
LFDEFCAG_00671 5.12e-126 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_00672 3.67e-253 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
LFDEFCAG_00675 7.89e-46 - - - L - - - Helix-turn-helix domain
LFDEFCAG_00677 1.53e-157 - - - L ko:K07497 - ko00000 hmm pf00665
LFDEFCAG_00678 7.75e-28 - - - L - - - reverse transcriptase
LFDEFCAG_00679 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LFDEFCAG_00680 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
LFDEFCAG_00681 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
LFDEFCAG_00682 3.54e-195 yycI - - S - - - YycH protein
LFDEFCAG_00683 3.55e-313 yycH - - S - - - YycH protein
LFDEFCAG_00684 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LFDEFCAG_00685 1.56e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LFDEFCAG_00687 2.54e-50 - - - - - - - -
LFDEFCAG_00688 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
LFDEFCAG_00689 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
LFDEFCAG_00690 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
LFDEFCAG_00691 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LFDEFCAG_00692 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
LFDEFCAG_00694 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LFDEFCAG_00695 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LFDEFCAG_00696 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LFDEFCAG_00697 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LFDEFCAG_00698 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LFDEFCAG_00699 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LFDEFCAG_00701 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LFDEFCAG_00703 3.25e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LFDEFCAG_00704 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LFDEFCAG_00705 4.96e-289 yttB - - EGP - - - Major Facilitator
LFDEFCAG_00706 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LFDEFCAG_00707 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LFDEFCAG_00708 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LFDEFCAG_00709 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LFDEFCAG_00710 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LFDEFCAG_00711 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LFDEFCAG_00712 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LFDEFCAG_00713 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LFDEFCAG_00714 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LFDEFCAG_00715 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
LFDEFCAG_00716 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LFDEFCAG_00717 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LFDEFCAG_00718 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LFDEFCAG_00719 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LFDEFCAG_00720 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LFDEFCAG_00721 4.56e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
LFDEFCAG_00722 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
LFDEFCAG_00723 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LFDEFCAG_00724 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LFDEFCAG_00725 3.74e-143 - - - S - - - Cell surface protein
LFDEFCAG_00726 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
LFDEFCAG_00728 0.0 - - - - - - - -
LFDEFCAG_00729 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LFDEFCAG_00731 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
LFDEFCAG_00732 4.11e-80 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
LFDEFCAG_00733 6.95e-204 degV1 - - S - - - DegV family
LFDEFCAG_00734 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
LFDEFCAG_00735 1.13e-182 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
LFDEFCAG_00736 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LFDEFCAG_00737 7.43e-130 padR - - K - - - Virulence activator alpha C-term
LFDEFCAG_00738 2.51e-103 - - - T - - - Universal stress protein family
LFDEFCAG_00739 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
LFDEFCAG_00740 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LFDEFCAG_00741 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFDEFCAG_00742 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LFDEFCAG_00743 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
LFDEFCAG_00744 2.54e-31 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LFDEFCAG_00745 1.15e-46 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LFDEFCAG_00746 3.19e-62 - - - - - - - -
LFDEFCAG_00747 8.74e-155 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
LFDEFCAG_00749 4e-91 - - - U ko:K03559 - ko00000,ko02000 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbB
LFDEFCAG_00750 3.75e-176 - - - U ko:K03561 - ko00000,ko02000 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbD
LFDEFCAG_00751 1.27e-211 - - - P - - - Voltage gated chloride channel
LFDEFCAG_00752 3.23e-66 - - - S - - - Phage gp6-like head-tail connector protein
LFDEFCAG_00753 6.01e-33 - - - S - - - Phage head-tail joining protein
LFDEFCAG_00754 6.59e-51 - - - - - - - -
LFDEFCAG_00755 7.75e-28 - - - - - - - -
LFDEFCAG_00756 1.27e-220 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LFDEFCAG_00757 1.59e-76 int3 - - L - - - Belongs to the 'phage' integrase family
LFDEFCAG_00758 1.09e-54 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
LFDEFCAG_00759 1.56e-22 - - - - - - - -
LFDEFCAG_00760 3.26e-24 - - - - - - - -
LFDEFCAG_00761 6.58e-24 - - - - - - - -
LFDEFCAG_00762 0.0 inlJ - - M - - - MucBP domain
LFDEFCAG_00763 0.0 - - - D - - - nuclear chromosome segregation
LFDEFCAG_00764 1.27e-109 - - - K - - - MarR family
LFDEFCAG_00765 9.28e-58 - - - - - - - -
LFDEFCAG_00766 1.28e-51 - - - - - - - -
LFDEFCAG_00767 2.96e-288 - - - L - - - Belongs to the 'phage' integrase family
LFDEFCAG_00768 3.02e-06 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LFDEFCAG_00770 3.96e-13 - - - - - - - -
LFDEFCAG_00771 6.2e-39 - - - - - - - -
LFDEFCAG_00772 1.96e-183 - - - L - - - DNA replication protein
LFDEFCAG_00773 0.0 - - - S - - - Virulence-associated protein E
LFDEFCAG_00774 6.4e-97 - - - - - - - -
LFDEFCAG_00776 1.32e-65 - - - S - - - Head-tail joining protein
LFDEFCAG_00777 3.67e-89 - - - L - - - HNH endonuclease
LFDEFCAG_00778 3.15e-108 - - - L - - - overlaps another CDS with the same product name
LFDEFCAG_00779 0.0 terL - - S - - - overlaps another CDS with the same product name
LFDEFCAG_00781 2.91e-254 - - - S - - - Phage portal protein
LFDEFCAG_00782 4.7e-264 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
LFDEFCAG_00783 2.9e-56 - - - S - - - Phage gp6-like head-tail connector protein
LFDEFCAG_00784 2.42e-48 - - - - - - - -
LFDEFCAG_00785 2.65e-119 - - - S - - - Abi-like protein
LFDEFCAG_00787 1.98e-40 - - - - - - - -
LFDEFCAG_00789 3.14e-277 int3 - - L - - - Belongs to the 'phage' integrase family
LFDEFCAG_00793 4.23e-19 - - - S ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
LFDEFCAG_00796 5.48e-100 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
LFDEFCAG_00798 3.41e-118 - - - - - - - -
LFDEFCAG_00799 5.5e-97 - - - E - - - IrrE N-terminal-like domain
LFDEFCAG_00800 4.65e-52 - - - K - - - Helix-turn-helix domain
LFDEFCAG_00803 8.29e-51 - - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
LFDEFCAG_00804 1.13e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
LFDEFCAG_00807 7.71e-71 - - - - - - - -
LFDEFCAG_00808 1.56e-103 - - - - - - - -
LFDEFCAG_00812 2.8e-70 - - - S - - - Bacteriophage Mu Gam like protein
LFDEFCAG_00813 1.97e-78 - - - - - - - -
LFDEFCAG_00814 1.01e-44 - - - L - - - Domain of unknown function (DUF4373)
LFDEFCAG_00815 1.81e-64 - - - - - - - -
LFDEFCAG_00816 1.58e-81 - - - - - - - -
LFDEFCAG_00817 2.82e-87 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
LFDEFCAG_00818 2.11e-07 - - - - - - - -
LFDEFCAG_00819 3.18e-106 - - - S - - - Phage transcriptional regulator, ArpU family
LFDEFCAG_00824 4.63e-32 - - - S - - - Protein of unknown function (DUF2829)
LFDEFCAG_00825 1.54e-102 - - - L ko:K07474 - ko00000 Terminase small subunit
LFDEFCAG_00826 2.08e-304 - - - S - - - Terminase-like family
LFDEFCAG_00827 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
LFDEFCAG_00828 4.98e-51 - - - J ko:K07584 - ko00000 Cysteine protease Prp
LFDEFCAG_00829 0.0 - - - S - - - Phage Mu protein F like protein
LFDEFCAG_00830 3.05e-41 - - - - - - - -
LFDEFCAG_00833 2.84e-64 - - - - - - - -
LFDEFCAG_00834 2.08e-222 - - - S - - - Phage major capsid protein E
LFDEFCAG_00836 1.68e-67 - - - - - - - -
LFDEFCAG_00837 9.63e-68 - - - - - - - -
LFDEFCAG_00838 5.34e-115 - - - - - - - -
LFDEFCAG_00839 3.49e-72 - - - - - - - -
LFDEFCAG_00840 7.42e-102 - - - S - - - Phage tail tube protein, TTP
LFDEFCAG_00841 4.97e-84 - - - - - - - -
LFDEFCAG_00842 0.0 - - - D - - - domain protein
LFDEFCAG_00843 8.96e-79 - - - - - - - -
LFDEFCAG_00844 0.0 - - - LM - - - DNA recombination
LFDEFCAG_00845 2.42e-90 - - - S - - - Protein of unknown function (DUF1617)
LFDEFCAG_00847 6.44e-264 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LFDEFCAG_00848 4.55e-64 - - - - - - - -
LFDEFCAG_00849 6.03e-59 - - - S - - - Bacteriophage holin
LFDEFCAG_00851 5.89e-95 - - - O - - - Subtilase family
LFDEFCAG_00852 1.03e-41 - - - O - - - ATPase family associated with various cellular activities (AAA)
LFDEFCAG_00855 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
LFDEFCAG_00856 1.81e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
LFDEFCAG_00857 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_00858 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
LFDEFCAG_00859 6.55e-183 - - - - - - - -
LFDEFCAG_00860 1.33e-77 - - - - - - - -
LFDEFCAG_00861 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LFDEFCAG_00862 2.1e-41 - - - - - - - -
LFDEFCAG_00863 2.65e-245 ampC - - V - - - Beta-lactamase
LFDEFCAG_00864 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LFDEFCAG_00865 1.06e-174 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
LFDEFCAG_00866 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
LFDEFCAG_00867 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LFDEFCAG_00868 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LFDEFCAG_00869 3.44e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LFDEFCAG_00870 4.39e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LFDEFCAG_00871 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LFDEFCAG_00872 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LFDEFCAG_00873 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
LFDEFCAG_00874 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LFDEFCAG_00875 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LFDEFCAG_00876 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LFDEFCAG_00877 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LFDEFCAG_00878 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LFDEFCAG_00879 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LFDEFCAG_00880 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LFDEFCAG_00881 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LFDEFCAG_00882 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LFDEFCAG_00883 3.96e-131 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LFDEFCAG_00884 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
LFDEFCAG_00885 5.3e-58 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LFDEFCAG_00886 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
LFDEFCAG_00887 3.56e-279 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LFDEFCAG_00888 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
LFDEFCAG_00889 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LFDEFCAG_00890 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_00891 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LFDEFCAG_00892 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LFDEFCAG_00893 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
LFDEFCAG_00894 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LFDEFCAG_00895 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LFDEFCAG_00896 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
LFDEFCAG_00897 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
LFDEFCAG_00898 1.2e-262 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
LFDEFCAG_00899 2.37e-107 uspA - - T - - - universal stress protein
LFDEFCAG_00900 1.34e-52 - - - - - - - -
LFDEFCAG_00901 7.27e-303 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LFDEFCAG_00902 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
LFDEFCAG_00903 3.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
LFDEFCAG_00904 2.22e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
LFDEFCAG_00905 3.22e-140 - - - L - - - Integrase
LFDEFCAG_00906 2.47e-26 - - - S - - - Protein of unknown function (DUF1617)
LFDEFCAG_00908 4.34e-55 - - - - - - - -
LFDEFCAG_00910 1.15e-112 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
LFDEFCAG_00911 9.77e-48 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LFDEFCAG_00912 1.77e-05 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
LFDEFCAG_00913 2.74e-200 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
LFDEFCAG_00915 1.07e-43 - - - S - - - Phage tail tube protein
LFDEFCAG_00917 4.36e-140 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LFDEFCAG_00918 4.82e-192 yleF - - K - - - Helix-turn-helix domain, rpiR family
LFDEFCAG_00919 2.76e-55 - - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
LFDEFCAG_00920 1.29e-254 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LFDEFCAG_00921 1.03e-33 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
LFDEFCAG_00922 5.99e-213 mleR - - K - - - LysR substrate binding domain
LFDEFCAG_00923 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LFDEFCAG_00924 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LFDEFCAG_00925 9.51e-210 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
LFDEFCAG_00926 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LFDEFCAG_00927 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
LFDEFCAG_00928 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LFDEFCAG_00929 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LFDEFCAG_00930 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LFDEFCAG_00931 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LFDEFCAG_00932 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
LFDEFCAG_00933 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
LFDEFCAG_00934 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LFDEFCAG_00935 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LFDEFCAG_00936 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
LFDEFCAG_00937 1.01e-190 malA - - S - - - maltodextrose utilization protein MalA
LFDEFCAG_00938 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_00939 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LFDEFCAG_00940 4.69e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LFDEFCAG_00941 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
LFDEFCAG_00942 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
LFDEFCAG_00943 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
LFDEFCAG_00944 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LFDEFCAG_00945 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
LFDEFCAG_00946 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
LFDEFCAG_00947 3.88e-239 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
LFDEFCAG_00948 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
LFDEFCAG_00949 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_00951 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
LFDEFCAG_00952 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
LFDEFCAG_00953 1.09e-148 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LFDEFCAG_00954 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
LFDEFCAG_00955 4.24e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_00956 7.14e-185 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
LFDEFCAG_00957 3.37e-115 - - - - - - - -
LFDEFCAG_00958 1.29e-190 - - - - - - - -
LFDEFCAG_00959 2.58e-181 - - - - - - - -
LFDEFCAG_00960 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
LFDEFCAG_00961 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LFDEFCAG_00963 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
LFDEFCAG_00964 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_00965 7.71e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
LFDEFCAG_00966 7.26e-265 - - - C - - - Oxidoreductase
LFDEFCAG_00967 0.0 - - - - - - - -
LFDEFCAG_00968 4.03e-132 - - - - - - - -
LFDEFCAG_00969 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LFDEFCAG_00970 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
LFDEFCAG_00971 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
LFDEFCAG_00972 1.34e-198 morA - - S - - - reductase
LFDEFCAG_00974 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
LFDEFCAG_00975 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LFDEFCAG_00976 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LFDEFCAG_00977 7.39e-87 - - - K - - - LytTr DNA-binding domain
LFDEFCAG_00978 2.14e-39 - - - S - - - Protein of unknown function (DUF3021)
LFDEFCAG_00979 2.31e-95 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LFDEFCAG_00980 1.27e-98 - - - K - - - Transcriptional regulator
LFDEFCAG_00981 5.13e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LFDEFCAG_00982 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LFDEFCAG_00983 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LFDEFCAG_00984 5.08e-192 - - - I - - - Alpha/beta hydrolase family
LFDEFCAG_00985 3.8e-161 - - - - - - - -
LFDEFCAG_00986 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
LFDEFCAG_00987 1.24e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
LFDEFCAG_00988 0.0 - - - L - - - HIRAN domain
LFDEFCAG_00989 7.45e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
LFDEFCAG_00990 6.4e-110 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
LFDEFCAG_00991 4.05e-82 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
LFDEFCAG_00992 2.91e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LFDEFCAG_00993 7.44e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LFDEFCAG_00994 2.27e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LFDEFCAG_00995 3.02e-228 - - - C - - - Zinc-binding dehydrogenase
LFDEFCAG_00996 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
LFDEFCAG_00997 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LFDEFCAG_00998 1.81e-98 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
LFDEFCAG_00999 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LFDEFCAG_01000 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
LFDEFCAG_01001 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
LFDEFCAG_01002 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
LFDEFCAG_01003 1.29e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
LFDEFCAG_01004 8.38e-193 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LFDEFCAG_01005 7.41e-167 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_01006 1.67e-54 - - - - - - - -
LFDEFCAG_01007 8.04e-184 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
LFDEFCAG_01008 4.07e-05 - - - - - - - -
LFDEFCAG_01009 5.9e-181 - - - - - - - -
LFDEFCAG_01010 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
LFDEFCAG_01011 2.38e-99 - - - - - - - -
LFDEFCAG_01012 2.14e-178 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
LFDEFCAG_01013 1.62e-217 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LFDEFCAG_01014 1.81e-89 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LFDEFCAG_01018 6.21e-36 - - - S - - - Domain of unknown function (DUF771)
LFDEFCAG_01019 3.08e-11 - - - - - - - -
LFDEFCAG_01020 6e-185 yknV - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_01021 9.15e-65 - - - S - - - Phage terminase, small subunit
LFDEFCAG_01022 5.51e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LFDEFCAG_01023 1.57e-142 - - - S - - - Protein of unknown function (DUF1648)
LFDEFCAG_01024 1.15e-104 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
LFDEFCAG_01025 4.02e-145 yktB - - S - - - Belongs to the UPF0637 family
LFDEFCAG_01026 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LFDEFCAG_01027 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LFDEFCAG_01028 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LFDEFCAG_01029 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LFDEFCAG_01030 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LFDEFCAG_01031 4.5e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
LFDEFCAG_01032 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LFDEFCAG_01033 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LFDEFCAG_01034 5.62e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LFDEFCAG_01035 1.35e-149 radC - - L ko:K03630 - ko00000 DNA repair protein
LFDEFCAG_01036 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
LFDEFCAG_01037 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LFDEFCAG_01038 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
LFDEFCAG_01039 2.2e-149 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LFDEFCAG_01040 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LFDEFCAG_01041 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LFDEFCAG_01042 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_01043 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LFDEFCAG_01044 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LFDEFCAG_01045 2.05e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
LFDEFCAG_01046 3.84e-316 ymfH - - S - - - Peptidase M16
LFDEFCAG_01047 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
LFDEFCAG_01048 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LFDEFCAG_01049 2.21e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LFDEFCAG_01050 9.9e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LFDEFCAG_01051 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LFDEFCAG_01052 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
LFDEFCAG_01053 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LFDEFCAG_01054 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LFDEFCAG_01055 1.35e-93 - - - - - - - -
LFDEFCAG_01056 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LFDEFCAG_01057 2.07e-118 - - - - - - - -
LFDEFCAG_01058 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LFDEFCAG_01059 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LFDEFCAG_01060 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LFDEFCAG_01061 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LFDEFCAG_01062 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LFDEFCAG_01063 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LFDEFCAG_01064 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
LFDEFCAG_01065 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LFDEFCAG_01066 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LFDEFCAG_01067 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
LFDEFCAG_01068 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LFDEFCAG_01069 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
LFDEFCAG_01070 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LFDEFCAG_01071 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LFDEFCAG_01072 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LFDEFCAG_01073 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
LFDEFCAG_01074 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LFDEFCAG_01075 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LFDEFCAG_01076 4.03e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LFDEFCAG_01077 7.94e-114 ykuL - - S - - - (CBS) domain
LFDEFCAG_01078 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LFDEFCAG_01079 4.54e-287 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LFDEFCAG_01080 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
LFDEFCAG_01081 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LFDEFCAG_01082 4.51e-79 - - - - - - - -
LFDEFCAG_01083 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
LFDEFCAG_01084 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LFDEFCAG_01085 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LFDEFCAG_01086 1.59e-210 - - - G - - - Xylose isomerase domain protein TIM barrel
LFDEFCAG_01087 8.49e-66 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
LFDEFCAG_01088 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
LFDEFCAG_01089 1.19e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LFDEFCAG_01090 1.55e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
LFDEFCAG_01091 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
LFDEFCAG_01092 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
LFDEFCAG_01093 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
LFDEFCAG_01094 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
LFDEFCAG_01095 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
LFDEFCAG_01097 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
LFDEFCAG_01098 3.31e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LFDEFCAG_01099 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LFDEFCAG_01100 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
LFDEFCAG_01101 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LFDEFCAG_01102 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
LFDEFCAG_01103 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LFDEFCAG_01104 3.3e-151 - - - S - - - Protein of unknown function (DUF1461)
LFDEFCAG_01105 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
LFDEFCAG_01106 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LFDEFCAG_01107 2.34e-97 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
LFDEFCAG_01108 1.29e-83 - - - - - - - -
LFDEFCAG_01109 1.58e-109 ypdD - - G - - - Glycosyl hydrolase family 92
LFDEFCAG_01110 1.18e-93 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LFDEFCAG_01111 1.36e-88 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
LFDEFCAG_01113 7.98e-80 - - - M - - - Lysin motif
LFDEFCAG_01114 4.75e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_01115 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_01116 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_01117 1.84e-295 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
LFDEFCAG_01118 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
LFDEFCAG_01119 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LFDEFCAG_01120 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
LFDEFCAG_01121 1.17e-135 - - - K - - - transcriptional regulator
LFDEFCAG_01122 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LFDEFCAG_01123 1.49e-63 - - - - - - - -
LFDEFCAG_01124 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
LFDEFCAG_01125 1.76e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LFDEFCAG_01126 2.87e-56 - - - - - - - -
LFDEFCAG_01127 6.77e-75 - - - - - - - -
LFDEFCAG_01128 1.81e-308 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_01129 1.61e-166 yidA - - K - - - Helix-turn-helix domain, rpiR family
LFDEFCAG_01130 2.42e-65 - - - - - - - -
LFDEFCAG_01131 3.28e-166 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
LFDEFCAG_01132 1.82e-316 hpk2 - - T - - - Histidine kinase
LFDEFCAG_01133 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
LFDEFCAG_01134 0.0 ydiC - - EGP - - - Major Facilitator
LFDEFCAG_01135 1.55e-55 - - - - - - - -
LFDEFCAG_01136 2.92e-57 - - - - - - - -
LFDEFCAG_01137 4.68e-152 - - - - - - - -
LFDEFCAG_01138 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LFDEFCAG_01139 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01140 8.9e-96 ywnA - - K - - - Transcriptional regulator
LFDEFCAG_01141 7.84e-92 - - - - - - - -
LFDEFCAG_01142 1.78e-128 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LFDEFCAG_01143 2.13e-184 - - - - - - - -
LFDEFCAG_01144 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LFDEFCAG_01145 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LFDEFCAG_01146 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LFDEFCAG_01147 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LFDEFCAG_01148 6.35e-56 - - - - - - - -
LFDEFCAG_01149 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
LFDEFCAG_01150 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
LFDEFCAG_01151 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
LFDEFCAG_01152 1.3e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LFDEFCAG_01153 1e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LFDEFCAG_01154 7.42e-125 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
LFDEFCAG_01155 1.82e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
LFDEFCAG_01156 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
LFDEFCAG_01157 1.2e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
LFDEFCAG_01158 2.98e-90 - - - - - - - -
LFDEFCAG_01159 1.22e-125 - - - - - - - -
LFDEFCAG_01160 5.92e-67 - - - - - - - -
LFDEFCAG_01161 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LFDEFCAG_01162 1.21e-111 - - - - - - - -
LFDEFCAG_01163 1.06e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
LFDEFCAG_01164 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_01165 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
LFDEFCAG_01166 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LFDEFCAG_01167 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LFDEFCAG_01169 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LFDEFCAG_01170 2.32e-43 ygzD - - K ko:K07729 - ko00000,ko03000 Transcriptional
LFDEFCAG_01171 1.2e-91 - - - - - - - -
LFDEFCAG_01172 3.68e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LFDEFCAG_01173 2.16e-201 dkgB - - S - - - reductase
LFDEFCAG_01174 2.28e-114 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LFDEFCAG_01175 2.02e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
LFDEFCAG_01176 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LFDEFCAG_01177 8.68e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
LFDEFCAG_01178 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
LFDEFCAG_01179 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFDEFCAG_01180 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LFDEFCAG_01181 3.81e-18 - - - - - - - -
LFDEFCAG_01182 3.69e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LFDEFCAG_01183 6.48e-210 fbpA - - K - - - Domain of unknown function (DUF814)
LFDEFCAG_01184 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
LFDEFCAG_01185 6.33e-46 - - - - - - - -
LFDEFCAG_01186 7.12e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
LFDEFCAG_01187 2.73e-147 pgm1 - - G - - - phosphoglycerate mutase
LFDEFCAG_01188 7.18e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LFDEFCAG_01189 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFDEFCAG_01190 3.22e-103 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LFDEFCAG_01191 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LFDEFCAG_01192 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LFDEFCAG_01193 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
LFDEFCAG_01195 0.0 - - - M - - - domain protein
LFDEFCAG_01196 5.86e-140 - - - T ko:K07168 - ko00000 CBS-domain-containing membrane protein
LFDEFCAG_01197 1.58e-29 - - - - - - - -
LFDEFCAG_01198 3.77e-19 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
LFDEFCAG_01199 1.21e-178 - - - L - - - Transposase and inactivated derivatives, IS30 family
LFDEFCAG_01200 5.03e-182 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LFDEFCAG_01201 1.63e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LFDEFCAG_01202 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
LFDEFCAG_01203 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LFDEFCAG_01204 7.35e-99 yjcF - - S - - - Acetyltransferase (GNAT) domain
LFDEFCAG_01205 0.0 - - - M - - - domain protein
LFDEFCAG_01206 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
LFDEFCAG_01207 3.1e-144 - - - S - - - Protein of unknown function (DUF1211)
LFDEFCAG_01208 1.45e-46 - - - - - - - -
LFDEFCAG_01209 2.61e-234 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LFDEFCAG_01210 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LFDEFCAG_01211 2.54e-17 rmeB - - K - - - transcriptional regulator, MerR family
LFDEFCAG_01212 1.71e-67 - - - S - - - Domain of unknown function (DU1801)
LFDEFCAG_01213 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LFDEFCAG_01214 1.07e-282 ysaA - - V - - - RDD family
LFDEFCAG_01215 6.46e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
LFDEFCAG_01216 1.09e-273 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LFDEFCAG_01217 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LFDEFCAG_01218 6.4e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LFDEFCAG_01219 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LFDEFCAG_01220 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LFDEFCAG_01221 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LFDEFCAG_01222 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LFDEFCAG_01223 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LFDEFCAG_01224 5.11e-67 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
LFDEFCAG_01225 2.9e-253 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LFDEFCAG_01226 6.8e-123 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LFDEFCAG_01227 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
LFDEFCAG_01228 9.51e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
LFDEFCAG_01229 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
LFDEFCAG_01230 5.39e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_01231 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LFDEFCAG_01232 2.79e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_01233 1.53e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LFDEFCAG_01234 1.43e-310 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
LFDEFCAG_01235 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
LFDEFCAG_01236 5.97e-210 - - - S - - - Uncharacterised protein, DegV family COG1307
LFDEFCAG_01237 5.32e-242 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LFDEFCAG_01238 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LFDEFCAG_01239 9.2e-62 - - - - - - - -
LFDEFCAG_01240 5.76e-107 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LFDEFCAG_01241 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
LFDEFCAG_01242 0.0 - - - S - - - ABC transporter, ATP-binding protein
LFDEFCAG_01243 7.08e-265 - - - T - - - diguanylate cyclase
LFDEFCAG_01244 1.11e-45 - - - - - - - -
LFDEFCAG_01245 2.29e-48 - - - - - - - -
LFDEFCAG_01246 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
LFDEFCAG_01247 1.37e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
LFDEFCAG_01248 1.65e-206 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LFDEFCAG_01250 2.68e-32 - - - - - - - -
LFDEFCAG_01251 1.9e-176 - - - F - - - NUDIX domain
LFDEFCAG_01252 1.96e-273 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
LFDEFCAG_01253 1.31e-64 - - - - - - - -
LFDEFCAG_01254 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
LFDEFCAG_01256 1.26e-218 - - - EG - - - EamA-like transporter family
LFDEFCAG_01257 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
LFDEFCAG_01258 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
LFDEFCAG_01259 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
LFDEFCAG_01260 0.0 yclK - - T - - - Histidine kinase
LFDEFCAG_01261 1.83e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
LFDEFCAG_01262 3.57e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
LFDEFCAG_01263 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LFDEFCAG_01264 2.1e-33 - - - - - - - -
LFDEFCAG_01265 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_01266 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LFDEFCAG_01267 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
LFDEFCAG_01268 4.63e-24 - - - - - - - -
LFDEFCAG_01269 2.16e-26 - - - - - - - -
LFDEFCAG_01270 3.69e-130 - - - L - - - Integrase
LFDEFCAG_01271 8.79e-239 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LFDEFCAG_01272 5.05e-130 - - - M - - - Parallel beta-helix repeats
LFDEFCAG_01273 1.33e-82 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
LFDEFCAG_01274 2.02e-214 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LFDEFCAG_01275 6.89e-68 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
LFDEFCAG_01276 1.27e-63 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LFDEFCAG_01277 2e-117 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
LFDEFCAG_01278 1.16e-99 cps3J - - M - - - Domain of unknown function (DUF4422)
LFDEFCAG_01279 1.43e-28 - - - S - - - O-antigen ligase like membrane protein
LFDEFCAG_01280 7.12e-09 - - - V - - - Beta-lactamase
LFDEFCAG_01281 2.23e-10 cap5B - - D - - - NUBPL iron-transfer P-loop NTPase
LFDEFCAG_01283 6.08e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
LFDEFCAG_01284 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LFDEFCAG_01285 7.42e-202 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LFDEFCAG_01286 4.55e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LFDEFCAG_01287 1.23e-276 pbpX - - V - - - Beta-lactamase
LFDEFCAG_01288 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LFDEFCAG_01289 2.9e-139 - - - - - - - -
LFDEFCAG_01290 7.62e-97 - - - - - - - -
LFDEFCAG_01292 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LFDEFCAG_01293 6.29e-281 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_01294 9.04e-14 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_01295 3.93e-99 - - - T - - - Universal stress protein family
LFDEFCAG_01297 9.46e-315 yfmL - - L - - - DEAD DEAH box helicase
LFDEFCAG_01298 7.89e-245 mocA - - S - - - Oxidoreductase
LFDEFCAG_01299 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
LFDEFCAG_01300 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
LFDEFCAG_01301 4.68e-187 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LFDEFCAG_01302 6.57e-195 gntR - - K - - - rpiR family
LFDEFCAG_01303 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LFDEFCAG_01304 2.88e-306 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_01305 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
LFDEFCAG_01306 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01307 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LFDEFCAG_01308 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
LFDEFCAG_01309 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LFDEFCAG_01310 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LFDEFCAG_01311 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LFDEFCAG_01312 9.48e-263 camS - - S - - - sex pheromone
LFDEFCAG_01313 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LFDEFCAG_01314 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LFDEFCAG_01315 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LFDEFCAG_01316 1.13e-120 yebE - - S - - - UPF0316 protein
LFDEFCAG_01317 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LFDEFCAG_01318 2.8e-145 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
LFDEFCAG_01319 9.47e-236 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LFDEFCAG_01320 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
LFDEFCAG_01321 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LFDEFCAG_01322 1.89e-208 - - - S - - - L,D-transpeptidase catalytic domain
LFDEFCAG_01323 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LFDEFCAG_01324 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LFDEFCAG_01325 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
LFDEFCAG_01326 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
LFDEFCAG_01327 0.0 - - - S ko:K06889 - ko00000 Alpha beta
LFDEFCAG_01328 6.07e-33 - - - - - - - -
LFDEFCAG_01329 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
LFDEFCAG_01330 0.0 - - - E ko:K03294 - ko00000 Amino Acid
LFDEFCAG_01331 9.09e-213 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
LFDEFCAG_01332 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
LFDEFCAG_01333 6.5e-215 mleR - - K - - - LysR family
LFDEFCAG_01334 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
LFDEFCAG_01335 1.98e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LFDEFCAG_01336 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LFDEFCAG_01337 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LFDEFCAG_01339 0.0 - - - S - - - MucBP domain
LFDEFCAG_01341 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
LFDEFCAG_01342 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
LFDEFCAG_01343 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LFDEFCAG_01344 1.97e-151 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01345 2.83e-267 - - - NU - - - Mycoplasma protein of unknown function, DUF285
LFDEFCAG_01346 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
LFDEFCAG_01347 4.28e-233 - - - S - - - Bacterial protein of unknown function (DUF916)
LFDEFCAG_01348 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
LFDEFCAG_01349 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
LFDEFCAG_01350 1.83e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LFDEFCAG_01351 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
LFDEFCAG_01352 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LFDEFCAG_01353 3.89e-210 - - - GM - - - NmrA-like family
LFDEFCAG_01354 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01355 3.32e-219 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFDEFCAG_01356 2.58e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFDEFCAG_01357 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LFDEFCAG_01358 1.42e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LFDEFCAG_01359 2.64e-141 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01360 0.0 yfjF - - U - - - Sugar (and other) transporter
LFDEFCAG_01363 1.97e-229 ydhF - - S - - - Aldo keto reductase
LFDEFCAG_01364 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
LFDEFCAG_01365 4.93e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
LFDEFCAG_01366 2.46e-127 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01367 3.27e-170 - - - S - - - KR domain
LFDEFCAG_01368 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
LFDEFCAG_01369 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
LFDEFCAG_01370 0.0 - - - M - - - Glycosyl hydrolases family 25
LFDEFCAG_01371 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LFDEFCAG_01372 2.65e-216 - - - GM - - - NmrA-like family
LFDEFCAG_01373 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01374 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LFDEFCAG_01375 1.38e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LFDEFCAG_01376 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LFDEFCAG_01377 4.52e-147 - - - M - - - ErfK YbiS YcfS YnhG
LFDEFCAG_01378 1.81e-272 - - - EGP - - - Major Facilitator
LFDEFCAG_01379 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
LFDEFCAG_01380 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
LFDEFCAG_01381 4.8e-156 - - - - - - - -
LFDEFCAG_01382 2.81e-301 - - - NU - - - Mycoplasma protein of unknown function, DUF285
LFDEFCAG_01383 1.47e-83 - - - - - - - -
LFDEFCAG_01384 4.48e-130 - - - S - - - WxL domain surface cell wall-binding
LFDEFCAG_01385 4.55e-243 ynjC - - S - - - Cell surface protein
LFDEFCAG_01386 2.63e-146 - - - S - - - GyrI-like small molecule binding domain
LFDEFCAG_01387 5.83e-87 - - - S - - - Iron-sulphur cluster biosynthesis
LFDEFCAG_01388 2.67e-225 - - - C - - - Alcohol dehydrogenase GroES-like domain
LFDEFCAG_01389 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
LFDEFCAG_01390 1.06e-238 - - - S - - - Cell surface protein
LFDEFCAG_01391 3.15e-98 - - - - - - - -
LFDEFCAG_01392 0.0 - - - - - - - -
LFDEFCAG_01393 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LFDEFCAG_01394 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
LFDEFCAG_01395 2.81e-181 - - - K - - - Helix-turn-helix domain
LFDEFCAG_01398 6.87e-33 - - - K - - - sequence-specific DNA binding
LFDEFCAG_01399 5.91e-234 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
LFDEFCAG_01400 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
LFDEFCAG_01401 9.11e-208 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
LFDEFCAG_01402 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
LFDEFCAG_01403 3.07e-241 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LFDEFCAG_01404 1.92e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
LFDEFCAG_01405 8.69e-230 citR - - K - - - sugar-binding domain protein
LFDEFCAG_01406 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LFDEFCAG_01407 1.53e-213 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LFDEFCAG_01408 9.69e-66 - - - - - - - -
LFDEFCAG_01409 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LFDEFCAG_01410 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LFDEFCAG_01411 1.18e-169 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LFDEFCAG_01412 1.57e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
LFDEFCAG_01413 1.28e-253 - - - K - - - Helix-turn-helix domain
LFDEFCAG_01414 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
LFDEFCAG_01415 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
LFDEFCAG_01416 3.05e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
LFDEFCAG_01417 4.93e-275 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LFDEFCAG_01419 1.82e-253 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LFDEFCAG_01420 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
LFDEFCAG_01421 6.45e-209 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFDEFCAG_01422 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LFDEFCAG_01423 1.35e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
LFDEFCAG_01424 2.46e-235 - - - S - - - Membrane
LFDEFCAG_01425 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
LFDEFCAG_01426 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LFDEFCAG_01427 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LFDEFCAG_01428 7.21e-193 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LFDEFCAG_01429 2.49e-186 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LFDEFCAG_01430 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LFDEFCAG_01431 3.42e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LFDEFCAG_01432 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LFDEFCAG_01433 3.19e-194 - - - S - - - FMN_bind
LFDEFCAG_01434 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LFDEFCAG_01435 5.37e-112 - - - S - - - NusG domain II
LFDEFCAG_01436 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
LFDEFCAG_01437 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LFDEFCAG_01438 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LFDEFCAG_01439 1.8e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LFDEFCAG_01440 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LFDEFCAG_01441 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LFDEFCAG_01442 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LFDEFCAG_01443 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LFDEFCAG_01444 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LFDEFCAG_01445 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LFDEFCAG_01446 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LFDEFCAG_01447 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LFDEFCAG_01448 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LFDEFCAG_01449 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LFDEFCAG_01450 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LFDEFCAG_01451 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LFDEFCAG_01452 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LFDEFCAG_01453 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LFDEFCAG_01454 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LFDEFCAG_01455 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LFDEFCAG_01456 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LFDEFCAG_01457 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LFDEFCAG_01458 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LFDEFCAG_01459 1.07e-61 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LFDEFCAG_01460 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LFDEFCAG_01461 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LFDEFCAG_01462 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LFDEFCAG_01463 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LFDEFCAG_01464 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LFDEFCAG_01465 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LFDEFCAG_01466 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LFDEFCAG_01467 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LFDEFCAG_01468 8.58e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
LFDEFCAG_01469 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LFDEFCAG_01470 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LFDEFCAG_01471 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01472 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LFDEFCAG_01473 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LFDEFCAG_01481 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LFDEFCAG_01482 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
LFDEFCAG_01483 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LFDEFCAG_01484 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
LFDEFCAG_01485 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LFDEFCAG_01486 1.7e-118 - - - K - - - Transcriptional regulator
LFDEFCAG_01487 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LFDEFCAG_01488 1.58e-197 - - - I - - - alpha/beta hydrolase fold
LFDEFCAG_01489 2.05e-153 - - - I - - - phosphatase
LFDEFCAG_01490 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LFDEFCAG_01491 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
LFDEFCAG_01492 4.6e-169 - - - S - - - Putative threonine/serine exporter
LFDEFCAG_01493 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LFDEFCAG_01494 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
LFDEFCAG_01495 1.36e-77 - - - - - - - -
LFDEFCAG_01496 7.79e-112 - - - K - - - MerR HTH family regulatory protein
LFDEFCAG_01497 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
LFDEFCAG_01498 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
LFDEFCAG_01499 9.04e-179 - - - - - - - -
LFDEFCAG_01500 1.75e-47 - - - K - - - MerR HTH family regulatory protein
LFDEFCAG_01501 3.36e-154 azlC - - E - - - branched-chain amino acid
LFDEFCAG_01502 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
LFDEFCAG_01503 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LFDEFCAG_01504 3.29e-279 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
LFDEFCAG_01505 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LFDEFCAG_01506 0.0 xylP2 - - G - - - symporter
LFDEFCAG_01507 2.01e-244 - - - I - - - alpha/beta hydrolase fold
LFDEFCAG_01508 3.33e-64 - - - - - - - -
LFDEFCAG_01509 1.19e-153 gpm5 - - G - - - Phosphoglycerate mutase family
LFDEFCAG_01510 3.36e-132 - - - K - - - FR47-like protein
LFDEFCAG_01511 3.44e-162 yibF - - S - - - overlaps another CDS with the same product name
LFDEFCAG_01512 3.42e-280 yibE - - S - - - overlaps another CDS with the same product name
LFDEFCAG_01513 3.91e-244 - - - - - - - -
LFDEFCAG_01514 1.18e-178 - - - S - - - NADPH-dependent FMN reductase
LFDEFCAG_01515 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LFDEFCAG_01516 1.65e-209 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LFDEFCAG_01517 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LFDEFCAG_01518 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
LFDEFCAG_01519 1.56e-55 - - - - - - - -
LFDEFCAG_01520 7.64e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LFDEFCAG_01521 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LFDEFCAG_01522 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
LFDEFCAG_01523 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LFDEFCAG_01524 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LFDEFCAG_01525 3.54e-105 - - - K - - - Transcriptional regulator
LFDEFCAG_01527 0.0 - - - C - - - FMN_bind
LFDEFCAG_01528 1.6e-219 - - - K - - - Transcriptional regulator
LFDEFCAG_01529 1.09e-123 - - - K - - - Helix-turn-helix domain
LFDEFCAG_01530 7.45e-180 - - - K - - - sequence-specific DNA binding
LFDEFCAG_01531 1.27e-115 - - - S - - - AAA domain
LFDEFCAG_01532 1.42e-08 - - - - - - - -
LFDEFCAG_01533 1.13e-62 - - - M - - - MucBP domain
LFDEFCAG_01534 0.0 - - - M - - - MucBP domain
LFDEFCAG_01535 2.81e-118 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
LFDEFCAG_01537 9.97e-108 - - - L - - - PFAM Integrase catalytic region
LFDEFCAG_01538 1.44e-33 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
LFDEFCAG_01539 2.38e-102 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LFDEFCAG_01540 0.000211 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
LFDEFCAG_01541 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
LFDEFCAG_01542 3.1e-131 - - - G - - - Glycogen debranching enzyme
LFDEFCAG_01543 4.46e-63 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
LFDEFCAG_01544 2.11e-211 yjdB - - S - - - Domain of unknown function (DUF4767)
LFDEFCAG_01545 4.76e-191 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
LFDEFCAG_01546 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
LFDEFCAG_01547 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
LFDEFCAG_01548 5.74e-32 - - - - - - - -
LFDEFCAG_01549 1.95e-116 - - - - - - - -
LFDEFCAG_01550 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
LFDEFCAG_01551 0.0 XK27_09800 - - I - - - Acyltransferase family
LFDEFCAG_01552 3.61e-61 - - - S - - - MORN repeat
LFDEFCAG_01553 6.35e-69 - - - - - - - -
LFDEFCAG_01554 9.14e-204 - - - S - - - Domain of unknown function (DUF4767)
LFDEFCAG_01555 1.85e-110 - - - - - - - -
LFDEFCAG_01556 2.45e-120 - - - D - - - nuclear chromosome segregation
LFDEFCAG_01557 2.56e-66 - - - K - - - Cro/C1-type HTH DNA-binding domain
LFDEFCAG_01558 2.28e-292 - - - S - - - Cysteine-rich secretory protein family
LFDEFCAG_01559 7.83e-301 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
LFDEFCAG_01560 1.85e-75 - - - K - - - HxlR-like helix-turn-helix
LFDEFCAG_01561 2.01e-149 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_01562 0.0 - - - L - - - AAA domain
LFDEFCAG_01563 5.57e-83 - - - K - - - Helix-turn-helix domain
LFDEFCAG_01564 1.08e-71 - - - - - - - -
LFDEFCAG_01565 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LFDEFCAG_01566 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LFDEFCAG_01567 1.46e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
LFDEFCAG_01568 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LFDEFCAG_01569 6.4e-143 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
LFDEFCAG_01570 1.39e-225 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LFDEFCAG_01571 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
LFDEFCAG_01572 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
LFDEFCAG_01573 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
LFDEFCAG_01574 1.61e-36 - - - - - - - -
LFDEFCAG_01575 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
LFDEFCAG_01576 4.6e-102 rppH3 - - F - - - NUDIX domain
LFDEFCAG_01577 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LFDEFCAG_01578 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01579 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
LFDEFCAG_01580 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
LFDEFCAG_01581 3.08e-93 - - - K - - - MarR family
LFDEFCAG_01582 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
LFDEFCAG_01583 2.98e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LFDEFCAG_01584 9.38e-317 steT - - E ko:K03294 - ko00000 amino acid
LFDEFCAG_01585 9.06e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
LFDEFCAG_01586 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LFDEFCAG_01587 1.34e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LFDEFCAG_01588 2.99e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LFDEFCAG_01589 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_01590 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_01591 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LFDEFCAG_01592 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_01594 1.28e-54 - - - - - - - -
LFDEFCAG_01595 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFDEFCAG_01596 3.21e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LFDEFCAG_01597 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
LFDEFCAG_01598 1.01e-188 - - - - - - - -
LFDEFCAG_01599 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
LFDEFCAG_01600 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LFDEFCAG_01601 6.02e-135 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
LFDEFCAG_01602 1.48e-27 - - - - - - - -
LFDEFCAG_01603 7.48e-96 - - - F - - - Nudix hydrolase
LFDEFCAG_01604 5.24e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
LFDEFCAG_01605 6.12e-115 - - - - - - - -
LFDEFCAG_01606 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
LFDEFCAG_01607 1.09e-60 - - - - - - - -
LFDEFCAG_01608 1.89e-90 - - - O - - - OsmC-like protein
LFDEFCAG_01609 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LFDEFCAG_01610 0.0 oatA - - I - - - Acyltransferase
LFDEFCAG_01611 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LFDEFCAG_01612 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
LFDEFCAG_01613 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LFDEFCAG_01614 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LFDEFCAG_01615 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LFDEFCAG_01616 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LFDEFCAG_01617 1.36e-27 - - - - - - - -
LFDEFCAG_01618 6.16e-107 - - - K - - - Transcriptional regulator
LFDEFCAG_01619 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
LFDEFCAG_01620 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LFDEFCAG_01621 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LFDEFCAG_01622 1.81e-225 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LFDEFCAG_01623 1.06e-314 - - - EGP - - - Major Facilitator
LFDEFCAG_01624 2.08e-117 - - - V - - - VanZ like family
LFDEFCAG_01625 3.88e-46 - - - - - - - -
LFDEFCAG_01626 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
LFDEFCAG_01628 4.13e-182 - - - - - - - -
LFDEFCAG_01629 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LFDEFCAG_01630 2.09e-42 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
LFDEFCAG_01631 1.73e-178 - - - EGP - - - Transmembrane secretion effector
LFDEFCAG_01632 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LFDEFCAG_01633 2.49e-95 - - - - - - - -
LFDEFCAG_01634 3.38e-70 - - - - - - - -
LFDEFCAG_01635 2.07e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LFDEFCAG_01636 1.21e-135 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_01637 1.33e-188 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
LFDEFCAG_01638 3.15e-158 - - - T - - - EAL domain
LFDEFCAG_01639 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LFDEFCAG_01640 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LFDEFCAG_01641 2.18e-182 ybbR - - S - - - YbbR-like protein
LFDEFCAG_01642 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LFDEFCAG_01643 2.31e-155 - - - S - - - Protein of unknown function (DUF1361)
LFDEFCAG_01644 3.59e-118 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LFDEFCAG_01645 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
LFDEFCAG_01646 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
LFDEFCAG_01647 1.71e-210 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
LFDEFCAG_01648 1.03e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LFDEFCAG_01649 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LFDEFCAG_01650 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
LFDEFCAG_01651 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
LFDEFCAG_01652 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
LFDEFCAG_01653 5.71e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LFDEFCAG_01654 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
LFDEFCAG_01655 7.98e-137 - - - - - - - -
LFDEFCAG_01656 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_01657 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_01658 0.0 - - - M - - - Domain of unknown function (DUF5011)
LFDEFCAG_01659 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LFDEFCAG_01660 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LFDEFCAG_01661 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
LFDEFCAG_01662 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LFDEFCAG_01663 0.0 eriC - - P ko:K03281 - ko00000 chloride
LFDEFCAG_01664 5.11e-171 - - - - - - - -
LFDEFCAG_01665 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LFDEFCAG_01666 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LFDEFCAG_01667 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LFDEFCAG_01668 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LFDEFCAG_01669 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
LFDEFCAG_01670 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
LFDEFCAG_01672 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LFDEFCAG_01673 1.55e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFDEFCAG_01674 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LFDEFCAG_01675 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LFDEFCAG_01676 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LFDEFCAG_01677 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LFDEFCAG_01678 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
LFDEFCAG_01679 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LFDEFCAG_01680 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LFDEFCAG_01681 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LFDEFCAG_01682 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LFDEFCAG_01683 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LFDEFCAG_01684 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
LFDEFCAG_01685 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
LFDEFCAG_01686 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LFDEFCAG_01687 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LFDEFCAG_01688 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
LFDEFCAG_01689 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LFDEFCAG_01690 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
LFDEFCAG_01691 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
LFDEFCAG_01692 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LFDEFCAG_01693 6.49e-171 - - - T - - - diguanylate cyclase activity
LFDEFCAG_01694 0.0 - - - S - - - Bacterial cellulose synthase subunit
LFDEFCAG_01695 2.74e-277 ydaM - - M - - - Glycosyl transferase family group 2
LFDEFCAG_01696 3.39e-256 - - - S - - - Protein conserved in bacteria
LFDEFCAG_01697 2.45e-310 - - - - - - - -
LFDEFCAG_01698 1.29e-206 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
LFDEFCAG_01699 0.0 nox - - C - - - NADH oxidase
LFDEFCAG_01700 1.06e-158 - - - T - - - Putative diguanylate phosphodiesterase
LFDEFCAG_01701 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LFDEFCAG_01702 2.82e-235 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LFDEFCAG_01703 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LFDEFCAG_01704 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LFDEFCAG_01705 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
LFDEFCAG_01706 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
LFDEFCAG_01707 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
LFDEFCAG_01708 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LFDEFCAG_01709 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LFDEFCAG_01710 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
LFDEFCAG_01711 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LFDEFCAG_01712 6.91e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LFDEFCAG_01713 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LFDEFCAG_01714 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LFDEFCAG_01715 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
LFDEFCAG_01716 8.03e-256 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LFDEFCAG_01717 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LFDEFCAG_01718 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LFDEFCAG_01719 3.43e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
LFDEFCAG_01720 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
LFDEFCAG_01721 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
LFDEFCAG_01722 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LFDEFCAG_01723 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
LFDEFCAG_01724 0.0 ydaO - - E - - - amino acid
LFDEFCAG_01725 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LFDEFCAG_01726 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LFDEFCAG_01727 1.68e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_01728 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LFDEFCAG_01729 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
LFDEFCAG_01730 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LFDEFCAG_01731 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LFDEFCAG_01732 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
LFDEFCAG_01733 3.25e-165 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
LFDEFCAG_01734 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
LFDEFCAG_01735 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LFDEFCAG_01736 5.35e-177 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
LFDEFCAG_01737 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_01738 1.97e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
LFDEFCAG_01739 2.18e-269 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
LFDEFCAG_01740 2.86e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LFDEFCAG_01741 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
LFDEFCAG_01742 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LFDEFCAG_01743 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
LFDEFCAG_01744 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LFDEFCAG_01745 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
LFDEFCAG_01746 2.22e-153 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LFDEFCAG_01747 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
LFDEFCAG_01748 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LFDEFCAG_01749 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LFDEFCAG_01750 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LFDEFCAG_01751 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LFDEFCAG_01752 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LFDEFCAG_01753 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
LFDEFCAG_01754 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LFDEFCAG_01755 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LFDEFCAG_01756 5.82e-141 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LFDEFCAG_01757 5.03e-50 - - - K - - - Helix-turn-helix domain
LFDEFCAG_01758 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LFDEFCAG_01759 1.78e-88 - - - L - - - nuclease
LFDEFCAG_01760 1.01e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
LFDEFCAG_01761 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LFDEFCAG_01762 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LFDEFCAG_01763 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LFDEFCAG_01764 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LFDEFCAG_01765 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LFDEFCAG_01766 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LFDEFCAG_01767 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LFDEFCAG_01768 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LFDEFCAG_01769 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
LFDEFCAG_01770 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
LFDEFCAG_01771 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFDEFCAG_01772 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LFDEFCAG_01773 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LFDEFCAG_01774 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LFDEFCAG_01775 4.84e-102 - - - L - - - Transposase
LFDEFCAG_01776 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LFDEFCAG_01777 2.15e-131 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LFDEFCAG_01778 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LFDEFCAG_01779 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LFDEFCAG_01780 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
LFDEFCAG_01781 2.65e-213 - - - G - - - Fructosamine kinase
LFDEFCAG_01782 1.35e-147 yjcF - - J - - - HAD-hyrolase-like
LFDEFCAG_01783 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LFDEFCAG_01784 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LFDEFCAG_01785 2.56e-76 - - - - - - - -
LFDEFCAG_01786 4.44e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LFDEFCAG_01787 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
LFDEFCAG_01788 1.11e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LFDEFCAG_01789 4.78e-65 - - - - - - - -
LFDEFCAG_01790 1.73e-67 - - - - - - - -
LFDEFCAG_01791 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LFDEFCAG_01792 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LFDEFCAG_01793 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LFDEFCAG_01794 3.27e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
LFDEFCAG_01795 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LFDEFCAG_01796 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
LFDEFCAG_01797 8.49e-266 pbpX2 - - V - - - Beta-lactamase
LFDEFCAG_01798 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LFDEFCAG_01799 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LFDEFCAG_01800 1.72e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LFDEFCAG_01801 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LFDEFCAG_01802 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LFDEFCAG_01803 7.56e-242 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LFDEFCAG_01804 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LFDEFCAG_01805 1.45e-114 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LFDEFCAG_01806 3.1e-248 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LFDEFCAG_01807 1.16e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LFDEFCAG_01808 9.84e-123 - - - - - - - -
LFDEFCAG_01809 2.21e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LFDEFCAG_01810 0.0 - - - G - - - Major Facilitator
LFDEFCAG_01811 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LFDEFCAG_01812 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LFDEFCAG_01813 3.28e-63 ylxQ - - J - - - ribosomal protein
LFDEFCAG_01814 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
LFDEFCAG_01815 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LFDEFCAG_01816 5.64e-107 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LFDEFCAG_01817 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LFDEFCAG_01818 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LFDEFCAG_01819 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LFDEFCAG_01820 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LFDEFCAG_01821 1.29e-189 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LFDEFCAG_01822 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LFDEFCAG_01823 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LFDEFCAG_01824 2.67e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LFDEFCAG_01825 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LFDEFCAG_01826 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
LFDEFCAG_01827 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LFDEFCAG_01828 1.02e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
LFDEFCAG_01829 9.74e-177 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LFDEFCAG_01830 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
LFDEFCAG_01831 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
LFDEFCAG_01832 7.68e-48 ynzC - - S - - - UPF0291 protein
LFDEFCAG_01833 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LFDEFCAG_01834 6.4e-122 - - - - - - - -
LFDEFCAG_01835 1.1e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
LFDEFCAG_01836 1.94e-97 - - - - - - - -
LFDEFCAG_01837 1.09e-86 - - - - - - - -
LFDEFCAG_01838 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
LFDEFCAG_01839 6.27e-131 - - - L - - - Helix-turn-helix domain
LFDEFCAG_01840 1.89e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
LFDEFCAG_01841 1.1e-183 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LFDEFCAG_01842 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LFDEFCAG_01843 1.08e-66 relE - - DJ ko:K06218 - ko00000,ko02048 ParE toxin of type II toxin-antitoxin system, parDE
LFDEFCAG_01844 2.97e-50 relB - - L ko:K18918 - ko00000,ko02048,ko03000 bifunctional antitoxin of the RelE-RelB toxin-antitoxin system transcriptional repressor
LFDEFCAG_01846 0.0 uvrA2 - - L - - - ABC transporter
LFDEFCAG_01847 2.9e-61 - - - - - - - -
LFDEFCAG_01848 8.82e-119 - - - - - - - -
LFDEFCAG_01849 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
LFDEFCAG_01850 1.23e-145 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_01851 4.56e-78 - - - - - - - -
LFDEFCAG_01852 5.37e-74 - - - - - - - -
LFDEFCAG_01853 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LFDEFCAG_01854 8.83e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LFDEFCAG_01855 7.83e-140 - - - - - - - -
LFDEFCAG_01856 1.97e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LFDEFCAG_01857 3.36e-88 - - - K - - - HxlR-like helix-turn-helix
LFDEFCAG_01858 3.88e-203 - - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LFDEFCAG_01859 2.91e-281 - - - C - - - Oxidoreductase
LFDEFCAG_01860 2.56e-95 - - - S - - - macrophage migration inhibitory factor
LFDEFCAG_01861 1.52e-207 - - - I - - - carboxylic ester hydrolase activity
LFDEFCAG_01862 5.25e-258 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LFDEFCAG_01863 1.27e-202 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LFDEFCAG_01864 6.66e-151 - - - GM - - - NAD(P)H-binding
LFDEFCAG_01865 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
LFDEFCAG_01866 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LFDEFCAG_01867 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
LFDEFCAG_01868 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_01869 1.16e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
LFDEFCAG_01871 7.61e-316 XK27_06930 - - V ko:K01421 - ko00000 domain protein
LFDEFCAG_01872 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LFDEFCAG_01873 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
LFDEFCAG_01874 1.56e-161 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LFDEFCAG_01875 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LFDEFCAG_01876 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_01877 3.93e-222 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LFDEFCAG_01878 7.18e-259 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
LFDEFCAG_01879 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
LFDEFCAG_01880 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
LFDEFCAG_01881 1.06e-193 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LFDEFCAG_01882 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LFDEFCAG_01883 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LFDEFCAG_01884 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LFDEFCAG_01885 2.95e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LFDEFCAG_01886 3.54e-121 mraW1 - - J - - - Putative rRNA methylase
LFDEFCAG_01887 9.32e-40 - - - - - - - -
LFDEFCAG_01888 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LFDEFCAG_01889 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LFDEFCAG_01890 0.0 - - - S - - - Pfam Methyltransferase
LFDEFCAG_01891 6.56e-22 - - - N - - - Cell shape-determining protein MreB
LFDEFCAG_01894 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
LFDEFCAG_01895 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
LFDEFCAG_01899 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
LFDEFCAG_01900 2.78e-71 - - - S - - - Cupin domain
LFDEFCAG_01901 1.53e-212 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
LFDEFCAG_01902 1.59e-247 ysdE - - P - - - Citrate transporter
LFDEFCAG_01903 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
LFDEFCAG_01904 2.65e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LFDEFCAG_01905 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LFDEFCAG_01906 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LFDEFCAG_01907 3.99e-177 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LFDEFCAG_01908 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LFDEFCAG_01909 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LFDEFCAG_01910 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LFDEFCAG_01911 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
LFDEFCAG_01912 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
LFDEFCAG_01913 7.59e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LFDEFCAG_01914 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LFDEFCAG_01915 1.19e-201 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LFDEFCAG_01917 2.88e-200 - - - G - - - Peptidase_C39 like family
LFDEFCAG_01918 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LFDEFCAG_01919 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
LFDEFCAG_01920 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
LFDEFCAG_01921 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
LFDEFCAG_01922 0.0 levR - - K - - - Sigma-54 interaction domain
LFDEFCAG_01923 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LFDEFCAG_01924 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LFDEFCAG_01925 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LFDEFCAG_01926 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
LFDEFCAG_01927 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
LFDEFCAG_01928 1.49e-183 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LFDEFCAG_01929 9.67e-175 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
LFDEFCAG_01930 1.32e-233 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LFDEFCAG_01931 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
LFDEFCAG_01932 7.04e-226 - - - EG - - - EamA-like transporter family
LFDEFCAG_01933 1.11e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LFDEFCAG_01934 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
LFDEFCAG_01935 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LFDEFCAG_01936 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LFDEFCAG_01937 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
LFDEFCAG_01938 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
LFDEFCAG_01939 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LFDEFCAG_01940 4.91e-265 yacL - - S - - - domain protein
LFDEFCAG_01941 7.51e-147 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
LFDEFCAG_01942 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
LFDEFCAG_01943 3.69e-169 - - - K - - - Helix-turn-helix domain, rpiR family
LFDEFCAG_01944 2.63e-206 - - - S - - - Alpha beta hydrolase
LFDEFCAG_01945 3.55e-146 - - - GM - - - NmrA-like family
LFDEFCAG_01946 4.14e-79 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
LFDEFCAG_01947 5.72e-207 - - - K - - - Transcriptional regulator
LFDEFCAG_01948 9.29e-222 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
LFDEFCAG_01950 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LFDEFCAG_01951 1.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
LFDEFCAG_01952 2.08e-265 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LFDEFCAG_01953 1.27e-174 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LFDEFCAG_01954 3.43e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_01956 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LFDEFCAG_01957 3.89e-94 - - - K - - - MarR family
LFDEFCAG_01958 1.49e-147 - - - S - - - Psort location CytoplasmicMembrane, score
LFDEFCAG_01959 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_01960 2.02e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LFDEFCAG_01961 5.21e-254 - - - - - - - -
LFDEFCAG_01962 2.59e-256 - - - - - - - -
LFDEFCAG_01963 2.45e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_01964 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LFDEFCAG_01965 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LFDEFCAG_01966 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LFDEFCAG_01967 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LFDEFCAG_01968 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LFDEFCAG_01969 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LFDEFCAG_01970 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LFDEFCAG_01971 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LFDEFCAG_01972 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LFDEFCAG_01973 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
LFDEFCAG_01974 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
LFDEFCAG_01975 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LFDEFCAG_01976 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LFDEFCAG_01977 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
LFDEFCAG_01978 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LFDEFCAG_01979 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LFDEFCAG_01980 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LFDEFCAG_01981 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LFDEFCAG_01982 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFDEFCAG_01983 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LFDEFCAG_01984 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LFDEFCAG_01985 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
LFDEFCAG_01986 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
LFDEFCAG_01987 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
LFDEFCAG_01988 1.49e-252 - - - M - - - MucBP domain
LFDEFCAG_01989 0.0 - - - - - - - -
LFDEFCAG_01990 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LFDEFCAG_01991 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LFDEFCAG_01992 1e-217 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LFDEFCAG_01993 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LFDEFCAG_01994 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
LFDEFCAG_01995 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
LFDEFCAG_01996 1.13e-257 yueF - - S - - - AI-2E family transporter
LFDEFCAG_01997 2.97e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LFDEFCAG_01998 6.46e-166 pbpX - - V - - - Beta-lactamase
LFDEFCAG_01999 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
LFDEFCAG_02000 3.97e-64 - - - K - - - sequence-specific DNA binding
LFDEFCAG_02001 1.94e-170 lytE - - M - - - NlpC/P60 family
LFDEFCAG_02002 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LFDEFCAG_02003 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
LFDEFCAG_02004 1.9e-168 - - - - - - - -
LFDEFCAG_02005 6.87e-131 - - - K - - - DNA-templated transcription, initiation
LFDEFCAG_02006 1.64e-35 - - - - - - - -
LFDEFCAG_02007 1.95e-41 - - - - - - - -
LFDEFCAG_02008 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
LFDEFCAG_02009 1.06e-68 - - - - - - - -
LFDEFCAG_02010 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
LFDEFCAG_02011 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LFDEFCAG_02012 5.36e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LFDEFCAG_02013 2.33e-99 - - - M - - - domain protein
LFDEFCAG_02014 5.32e-109 - - - T - - - Universal stress protein family
LFDEFCAG_02015 1.3e-202 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LFDEFCAG_02016 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_02017 7.74e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LFDEFCAG_02019 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
LFDEFCAG_02020 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LFDEFCAG_02021 3.62e-288 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LFDEFCAG_02022 1.46e-106 ypmB - - S - - - protein conserved in bacteria
LFDEFCAG_02023 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LFDEFCAG_02024 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
LFDEFCAG_02025 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
LFDEFCAG_02026 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
LFDEFCAG_02027 4.98e-250 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LFDEFCAG_02028 3.22e-245 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LFDEFCAG_02029 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LFDEFCAG_02030 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
LFDEFCAG_02031 2.18e-146 - - - S - - - Domain of unknown function (DUF4767)
LFDEFCAG_02032 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
LFDEFCAG_02033 1.57e-191 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LFDEFCAG_02034 0.0 - - - E ko:K03294 - ko00000 Amino Acid
LFDEFCAG_02035 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LFDEFCAG_02036 3.23e-58 - - - - - - - -
LFDEFCAG_02037 1.25e-66 - - - - - - - -
LFDEFCAG_02038 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
LFDEFCAG_02039 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
LFDEFCAG_02040 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LFDEFCAG_02041 4.87e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
LFDEFCAG_02042 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LFDEFCAG_02043 1.06e-53 - - - - - - - -
LFDEFCAG_02044 4e-40 - - - S - - - CsbD-like
LFDEFCAG_02045 2.22e-55 - - - S - - - transglycosylase associated protein
LFDEFCAG_02046 5.79e-21 - - - - - - - -
LFDEFCAG_02047 1.46e-46 - - - - - - - -
LFDEFCAG_02048 7.27e-211 - - - I - - - Diacylglycerol kinase catalytic domain
LFDEFCAG_02049 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
LFDEFCAG_02050 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
LFDEFCAG_02051 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
LFDEFCAG_02052 2.05e-55 - - - - - - - -
LFDEFCAG_02053 5.93e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
LFDEFCAG_02054 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
LFDEFCAG_02055 8e-275 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LFDEFCAG_02056 2.02e-39 - - - - - - - -
LFDEFCAG_02057 1.48e-71 - - - - - - - -
LFDEFCAG_02058 2.19e-07 - - - K - - - transcriptional regulator
LFDEFCAG_02059 1.73e-113 - - - S - - - Protein of unknown function with HXXEE motif
LFDEFCAG_02060 1.14e-193 - - - O - - - Band 7 protein
LFDEFCAG_02061 0.0 - - - EGP - - - Major Facilitator
LFDEFCAG_02062 1.49e-121 - - - K - - - transcriptional regulator
LFDEFCAG_02063 6.25e-246 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LFDEFCAG_02064 4.94e-114 ykhA - - I - - - Thioesterase superfamily
LFDEFCAG_02065 3.73e-207 - - - K - - - LysR substrate binding domain
LFDEFCAG_02066 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LFDEFCAG_02067 1.75e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
LFDEFCAG_02068 7.68e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LFDEFCAG_02069 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
LFDEFCAG_02070 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LFDEFCAG_02071 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
LFDEFCAG_02072 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LFDEFCAG_02073 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LFDEFCAG_02074 1.54e-289 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LFDEFCAG_02075 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LFDEFCAG_02076 4.93e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
LFDEFCAG_02077 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LFDEFCAG_02078 1.97e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LFDEFCAG_02079 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LFDEFCAG_02080 8.02e-230 yneE - - K - - - Transcriptional regulator
LFDEFCAG_02081 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LFDEFCAG_02082 1.09e-79 - - - S - - - Protein of unknown function (DUF1648)
LFDEFCAG_02083 2.3e-253 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LFDEFCAG_02084 2.38e-225 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
LFDEFCAG_02085 4.84e-125 entB - - Q - - - Isochorismatase family
LFDEFCAG_02086 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LFDEFCAG_02087 1.47e-286 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LFDEFCAG_02088 6.4e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LFDEFCAG_02089 1.66e-156 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LFDEFCAG_02090 7.03e-225 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LFDEFCAG_02091 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
LFDEFCAG_02092 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
LFDEFCAG_02094 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
LFDEFCAG_02095 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LFDEFCAG_02096 9.06e-112 - - - - - - - -
LFDEFCAG_02097 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
LFDEFCAG_02098 6.21e-68 - - - - - - - -
LFDEFCAG_02099 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LFDEFCAG_02100 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LFDEFCAG_02101 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LFDEFCAG_02102 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LFDEFCAG_02103 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LFDEFCAG_02104 9.38e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LFDEFCAG_02105 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LFDEFCAG_02106 7.71e-298 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LFDEFCAG_02107 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LFDEFCAG_02108 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LFDEFCAG_02109 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LFDEFCAG_02110 1.26e-243 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LFDEFCAG_02111 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LFDEFCAG_02112 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
LFDEFCAG_02113 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
LFDEFCAG_02114 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LFDEFCAG_02115 1.84e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LFDEFCAG_02116 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LFDEFCAG_02117 1.21e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LFDEFCAG_02118 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LFDEFCAG_02119 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LFDEFCAG_02120 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LFDEFCAG_02121 5.2e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LFDEFCAG_02122 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LFDEFCAG_02123 1.24e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LFDEFCAG_02124 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LFDEFCAG_02125 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LFDEFCAG_02126 3.51e-74 - - - - - - - -
LFDEFCAG_02127 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LFDEFCAG_02128 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LFDEFCAG_02129 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LFDEFCAG_02130 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02131 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LFDEFCAG_02132 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LFDEFCAG_02133 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
LFDEFCAG_02134 6.68e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LFDEFCAG_02135 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LFDEFCAG_02136 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LFDEFCAG_02137 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LFDEFCAG_02138 4.86e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LFDEFCAG_02139 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
LFDEFCAG_02140 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LFDEFCAG_02141 2.46e-248 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LFDEFCAG_02142 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LFDEFCAG_02143 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
LFDEFCAG_02144 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LFDEFCAG_02145 4.04e-125 - - - K - - - Transcriptional regulator
LFDEFCAG_02146 9.81e-27 - - - - - - - -
LFDEFCAG_02149 2.97e-41 - - - - - - - -
LFDEFCAG_02150 3.11e-73 - - - - - - - -
LFDEFCAG_02151 2.92e-126 - - - S - - - Protein conserved in bacteria
LFDEFCAG_02152 1.34e-232 - - - - - - - -
LFDEFCAG_02153 5.08e-205 - - - - - - - -
LFDEFCAG_02154 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LFDEFCAG_02155 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
LFDEFCAG_02156 1.33e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LFDEFCAG_02157 9.07e-178 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
LFDEFCAG_02158 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
LFDEFCAG_02159 6.68e-89 yqhL - - P - - - Rhodanese-like protein
LFDEFCAG_02160 1.62e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
LFDEFCAG_02161 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LFDEFCAG_02162 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
LFDEFCAG_02163 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
LFDEFCAG_02164 2.74e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LFDEFCAG_02165 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LFDEFCAG_02166 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LFDEFCAG_02167 0.0 - - - S - - - membrane
LFDEFCAG_02168 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
LFDEFCAG_02169 5.72e-99 - - - K - - - LytTr DNA-binding domain
LFDEFCAG_02170 9.72e-146 - - - S - - - membrane
LFDEFCAG_02171 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LFDEFCAG_02172 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LFDEFCAG_02173 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LFDEFCAG_02174 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LFDEFCAG_02175 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LFDEFCAG_02176 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
LFDEFCAG_02177 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LFDEFCAG_02178 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LFDEFCAG_02179 2.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LFDEFCAG_02180 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LFDEFCAG_02181 7.22e-122 - - - S - - - SdpI/YhfL protein family
LFDEFCAG_02182 5.55e-288 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LFDEFCAG_02183 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
LFDEFCAG_02184 1.59e-217 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
LFDEFCAG_02185 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LFDEFCAG_02186 1.38e-155 csrR - - K - - - response regulator
LFDEFCAG_02187 1.8e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LFDEFCAG_02188 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LFDEFCAG_02189 3.79e-224 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LFDEFCAG_02190 3.06e-124 - - - S - - - Peptidase propeptide and YPEB domain
LFDEFCAG_02191 2.12e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
LFDEFCAG_02192 7.16e-279 ylbM - - S - - - Belongs to the UPF0348 family
LFDEFCAG_02193 3.3e-180 yqeM - - Q - - - Methyltransferase
LFDEFCAG_02194 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LFDEFCAG_02195 1.71e-149 yqeK - - H - - - Hydrolase, HD family
LFDEFCAG_02196 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LFDEFCAG_02197 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
LFDEFCAG_02198 2.57e-274 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
LFDEFCAG_02199 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
LFDEFCAG_02200 6.32e-114 - - - - - - - -
LFDEFCAG_02201 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
LFDEFCAG_02202 6.86e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LFDEFCAG_02203 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
LFDEFCAG_02204 4.79e-250 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LFDEFCAG_02205 7.03e-307 - - - L ko:K07478 - ko00000 AAA C-terminal domain
LFDEFCAG_02206 2.76e-74 - - - - - - - -
LFDEFCAG_02207 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LFDEFCAG_02208 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LFDEFCAG_02209 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LFDEFCAG_02210 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LFDEFCAG_02211 1.91e-143 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LFDEFCAG_02212 3.62e-123 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
LFDEFCAG_02213 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LFDEFCAG_02214 4.53e-132 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LFDEFCAG_02215 1.85e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LFDEFCAG_02216 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LFDEFCAG_02217 3.46e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
LFDEFCAG_02218 4.45e-58 - - - S - - - Phage minor structural protein GP20
LFDEFCAG_02220 5.12e-46 - - - S - - - Phage Mu protein F like protein
LFDEFCAG_02222 1.8e-96 - - - - - - - -
LFDEFCAG_02223 8.63e-226 - - - - - - - -
LFDEFCAG_02224 2.69e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
LFDEFCAG_02225 2.35e-126 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
LFDEFCAG_02226 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
LFDEFCAG_02227 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LFDEFCAG_02228 1.27e-250 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
LFDEFCAG_02229 9.07e-107 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LFDEFCAG_02230 5.2e-294 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
LFDEFCAG_02231 9.62e-116 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LFDEFCAG_02232 1.08e-111 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LFDEFCAG_02233 5.73e-129 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LFDEFCAG_02234 8.84e-52 - - - - - - - -
LFDEFCAG_02235 1.48e-98 - 2.7.13.3 - T ko:K07683,ko:K10851 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 phosphoenolpyruvate-protein phosphotransferase activity
LFDEFCAG_02236 8.17e-242 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
LFDEFCAG_02237 7.76e-152 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
LFDEFCAG_02238 6.1e-64 - - - - - - - -
LFDEFCAG_02239 1.76e-232 - - - - - - - -
LFDEFCAG_02240 4.87e-205 - - - H - - - geranyltranstransferase activity
LFDEFCAG_02241 7.79e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
LFDEFCAG_02242 4.08e-78 - - - S - - - Iron-sulfur cluster assembly protein
LFDEFCAG_02243 1.98e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
LFDEFCAG_02244 3.92e-248 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LFDEFCAG_02245 7.86e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
LFDEFCAG_02246 6.26e-92 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
LFDEFCAG_02247 6.7e-107 - - - C - - - Flavodoxin
LFDEFCAG_02248 6.56e-211 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LFDEFCAG_02249 1.15e-161 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LFDEFCAG_02250 6.87e-236 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LFDEFCAG_02251 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
LFDEFCAG_02252 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
LFDEFCAG_02253 6.39e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LFDEFCAG_02254 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
LFDEFCAG_02255 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
LFDEFCAG_02256 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
LFDEFCAG_02257 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
LFDEFCAG_02258 3.04e-29 - - - S - - - Virus attachment protein p12 family
LFDEFCAG_02259 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LFDEFCAG_02260 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LFDEFCAG_02261 1.45e-145 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LFDEFCAG_02262 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
LFDEFCAG_02263 1.35e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LFDEFCAG_02264 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
LFDEFCAG_02265 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_02266 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02267 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
LFDEFCAG_02268 6.76e-73 - - - - - - - -
LFDEFCAG_02269 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LFDEFCAG_02270 3.95e-150 draG - - O - - - ADP-ribosylglycohydrolase
LFDEFCAG_02271 2.34e-134 - - - S - - - WxL domain surface cell wall-binding
LFDEFCAG_02272 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
LFDEFCAG_02273 3.36e-248 - - - S - - - Fn3-like domain
LFDEFCAG_02274 1.58e-64 - - - - - - - -
LFDEFCAG_02275 0.0 - - - - - - - -
LFDEFCAG_02276 5.19e-309 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
LFDEFCAG_02277 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_02278 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
LFDEFCAG_02279 1.96e-137 - - - - - - - -
LFDEFCAG_02280 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
LFDEFCAG_02281 3.01e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LFDEFCAG_02282 3.76e-287 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
LFDEFCAG_02283 1.44e-109 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LFDEFCAG_02284 2.86e-216 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LFDEFCAG_02285 0.0 - - - S - - - membrane
LFDEFCAG_02286 1.4e-90 - - - S - - - NUDIX domain
LFDEFCAG_02287 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LFDEFCAG_02288 1.15e-235 ykoT - - M - - - Glycosyl transferase family 2
LFDEFCAG_02289 0.0 - - - L - - - MutS domain V
LFDEFCAG_02290 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
LFDEFCAG_02291 4.09e-253 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LFDEFCAG_02292 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
LFDEFCAG_02293 3.44e-269 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LFDEFCAG_02294 3.88e-20 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LFDEFCAG_02296 1.21e-125 - - - M - - - domain protein
LFDEFCAG_02297 1.25e-25 - - - M - - - domain protein
LFDEFCAG_02298 1.78e-72 - - - M - - - domain protein
LFDEFCAG_02299 6.78e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
LFDEFCAG_02300 4.43e-129 - - - - - - - -
LFDEFCAG_02301 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LFDEFCAG_02302 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
LFDEFCAG_02303 4.45e-225 - - - K - - - LysR substrate binding domain
LFDEFCAG_02304 7.73e-230 - - - M - - - Peptidase family S41
LFDEFCAG_02305 5.21e-273 - - - - - - - -
LFDEFCAG_02306 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
LFDEFCAG_02307 0.0 yhaN - - L - - - AAA domain
LFDEFCAG_02308 4.47e-296 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
LFDEFCAG_02309 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
LFDEFCAG_02310 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LFDEFCAG_02311 2.43e-18 - - - - - - - -
LFDEFCAG_02312 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LFDEFCAG_02313 9.65e-272 arcT - - E - - - Aminotransferase
LFDEFCAG_02314 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
LFDEFCAG_02315 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
LFDEFCAG_02316 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LFDEFCAG_02317 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
LFDEFCAG_02318 3.13e-274 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
LFDEFCAG_02319 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LFDEFCAG_02320 1.77e-286 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_02321 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LFDEFCAG_02322 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
LFDEFCAG_02323 5.44e-104 - - - S - - - Domain of unknown function (DUF3284)
LFDEFCAG_02324 0.0 celR - - K - - - PRD domain
LFDEFCAG_02325 6.25e-138 - - - - - - - -
LFDEFCAG_02326 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
LFDEFCAG_02327 5.64e-107 - - - - - - - -
LFDEFCAG_02328 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LFDEFCAG_02329 9.97e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
LFDEFCAG_02332 1.79e-42 - - - - - - - -
LFDEFCAG_02333 2.51e-315 dinF - - V - - - MatE
LFDEFCAG_02334 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
LFDEFCAG_02335 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
LFDEFCAG_02336 5.68e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
LFDEFCAG_02337 3.06e-144 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LFDEFCAG_02338 8.91e-293 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
LFDEFCAG_02339 0.0 - - - S - - - Protein conserved in bacteria
LFDEFCAG_02340 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LFDEFCAG_02341 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LFDEFCAG_02342 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
LFDEFCAG_02343 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
LFDEFCAG_02344 3.89e-237 - - - - - - - -
LFDEFCAG_02345 9.03e-16 - - - - - - - -
LFDEFCAG_02346 6.09e-87 - - - - - - - -
LFDEFCAG_02348 2.91e-176 - - - K - - - helix_turn_helix, arabinose operon control protein
LFDEFCAG_02349 8.42e-190 cps3J - - M - - - Domain of unknown function (DUF4422)
LFDEFCAG_02350 5.06e-260 cps3I - - G - - - Acyltransferase family
LFDEFCAG_02351 1.03e-264 cps3H - - - - - - -
LFDEFCAG_02352 1.73e-207 cps3F - - - - - - -
LFDEFCAG_02353 2.92e-145 cps3E - - - - - - -
LFDEFCAG_02354 1.6e-259 cps3D - - - - - - -
LFDEFCAG_02355 2.31e-281 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
LFDEFCAG_02356 5.21e-226 - - - S - - - Glycosyltransferase like family 2
LFDEFCAG_02357 1.54e-219 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
LFDEFCAG_02358 7.72e-35 - - - S - - - Barstar (barnase inhibitor)
LFDEFCAG_02359 8.72e-73 - - - S - - - Immunity protein 63
LFDEFCAG_02361 1.63e-145 - - - - - - - -
LFDEFCAG_02363 2.87e-192 - - - L - - - Transposase and inactivated derivatives, IS30 family
LFDEFCAG_02364 9.94e-142 - - - - - - - -
LFDEFCAG_02365 6.56e-174 - - - - - - - -
LFDEFCAG_02366 9.17e-41 - - - - - - - -
LFDEFCAG_02367 3.07e-48 - - - - - - - -
LFDEFCAG_02368 1.29e-152 - - - - - - - -
LFDEFCAG_02370 3.23e-58 - - - - - - - -
LFDEFCAG_02371 5.45e-46 - - - M ko:K21493 - ko00000,ko01000,ko02048 self proteolysis
LFDEFCAG_02372 3.85e-54 - - - M ko:K21493 - ko00000,ko01000,ko02048 self proteolysis
LFDEFCAG_02375 0.0 mdr - - EGP - - - Major Facilitator
LFDEFCAG_02376 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LFDEFCAG_02377 5.79e-158 - - - - - - - -
LFDEFCAG_02378 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LFDEFCAG_02379 3.91e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
LFDEFCAG_02380 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LFDEFCAG_02381 2.08e-239 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LFDEFCAG_02382 1.14e-293 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LFDEFCAG_02384 1.7e-199 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
LFDEFCAG_02385 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
LFDEFCAG_02386 2.07e-123 - - - - - - - -
LFDEFCAG_02387 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
LFDEFCAG_02388 5.4e-118 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
LFDEFCAG_02399 3.71e-105 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LFDEFCAG_02400 6.08e-179 - - - K - - - DeoR C terminal sensor domain
LFDEFCAG_02401 8.35e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
LFDEFCAG_02402 6.57e-311 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
LFDEFCAG_02403 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LFDEFCAG_02404 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
LFDEFCAG_02405 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
LFDEFCAG_02406 1.31e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
LFDEFCAG_02407 1.45e-162 - - - S - - - Membrane
LFDEFCAG_02408 4.04e-94 yueI - - S - - - Protein of unknown function (DUF1694)
LFDEFCAG_02409 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LFDEFCAG_02410 5.03e-95 - - - K - - - Transcriptional regulator
LFDEFCAG_02411 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LFDEFCAG_02412 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
LFDEFCAG_02414 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
LFDEFCAG_02415 1.48e-95 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
LFDEFCAG_02416 7.24e-23 - - - - - - - -
LFDEFCAG_02417 2.56e-261 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LFDEFCAG_02418 3.67e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LFDEFCAG_02419 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
LFDEFCAG_02420 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
LFDEFCAG_02421 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
LFDEFCAG_02422 1.06e-16 - - - - - - - -
LFDEFCAG_02423 8.56e-116 - - - T - - - ECF transporter, substrate-specific component
LFDEFCAG_02424 1.16e-89 - - - S - - - Pyrimidine dimer DNA glycosylase
LFDEFCAG_02425 1.04e-287 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
LFDEFCAG_02426 2.67e-153 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LFDEFCAG_02427 1.9e-163 icaA - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyltransferases, probably involved in cell wall biogenesis
LFDEFCAG_02429 6.55e-62 icaB - - G ko:K21478 - ko00000,ko01000 Polysaccharide deacetylase
LFDEFCAG_02430 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LFDEFCAG_02431 6.69e-149 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
LFDEFCAG_02432 3.53e-100 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LFDEFCAG_02433 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LFDEFCAG_02434 1.69e-295 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LFDEFCAG_02435 1.32e-240 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
LFDEFCAG_02436 9.32e-312 - - - K ko:K02538 - ko00000,ko03000 PRD domain
LFDEFCAG_02438 3.29e-99 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LFDEFCAG_02439 5.14e-62 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LFDEFCAG_02440 3.64e-224 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
LFDEFCAG_02441 3.15e-162 alsE - - G ko:K17195 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Ribulose-phosphate 3 epimerase family
LFDEFCAG_02442 1.5e-149 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LFDEFCAG_02443 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LFDEFCAG_02444 4.78e-182 yxeH - - S - - - hydrolase
LFDEFCAG_02445 7.16e-231 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LFDEFCAG_02447 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
LFDEFCAG_02448 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
LFDEFCAG_02449 2.18e-221 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
LFDEFCAG_02450 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LFDEFCAG_02451 1.85e-100 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LFDEFCAG_02452 8.36e-87 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LFDEFCAG_02453 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LFDEFCAG_02454 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LFDEFCAG_02455 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LFDEFCAG_02456 1.51e-199 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LFDEFCAG_02457 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LFDEFCAG_02458 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LFDEFCAG_02459 2.53e-266 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LFDEFCAG_02460 8.36e-203 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
LFDEFCAG_02461 1.97e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LFDEFCAG_02462 1.77e-315 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_02463 1.82e-172 - - - K - - - UTRA domain
LFDEFCAG_02464 5.1e-198 estA - - S - - - Putative esterase
LFDEFCAG_02465 1.36e-79 - - - - - - - -
LFDEFCAG_02466 1.3e-261 - - - EGP - - - Major Facilitator Superfamily
LFDEFCAG_02467 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
LFDEFCAG_02468 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
LFDEFCAG_02469 1.82e-190 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LFDEFCAG_02470 1.64e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFDEFCAG_02471 3.45e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFDEFCAG_02472 2.33e-281 - - - EGP - - - Major Facilitator Superfamily
LFDEFCAG_02473 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
LFDEFCAG_02474 3.21e-212 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LFDEFCAG_02475 2.2e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LFDEFCAG_02476 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LFDEFCAG_02477 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LFDEFCAG_02478 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
LFDEFCAG_02479 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
LFDEFCAG_02480 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LFDEFCAG_02481 3.51e-252 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LFDEFCAG_02482 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LFDEFCAG_02483 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LFDEFCAG_02484 4.7e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
LFDEFCAG_02485 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
LFDEFCAG_02486 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LFDEFCAG_02487 1.26e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LFDEFCAG_02488 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LFDEFCAG_02489 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LFDEFCAG_02490 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LFDEFCAG_02491 1.94e-130 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
LFDEFCAG_02492 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
LFDEFCAG_02493 1.45e-297 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
LFDEFCAG_02494 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
LFDEFCAG_02495 8.32e-293 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
LFDEFCAG_02496 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
LFDEFCAG_02497 4.73e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LFDEFCAG_02498 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
LFDEFCAG_02499 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LFDEFCAG_02500 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LFDEFCAG_02501 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
LFDEFCAG_02502 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LFDEFCAG_02503 4.03e-283 - - - S - - - associated with various cellular activities
LFDEFCAG_02504 4.16e-314 - - - S - - - Putative metallopeptidase domain
LFDEFCAG_02505 1.03e-65 - - - - - - - -
LFDEFCAG_02506 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
LFDEFCAG_02507 1.58e-59 - - - - - - - -
LFDEFCAG_02508 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
LFDEFCAG_02509 1.68e-157 - - - S - - - WxL domain surface cell wall-binding
LFDEFCAG_02510 1.83e-235 - - - S - - - Cell surface protein
LFDEFCAG_02511 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
LFDEFCAG_02512 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
LFDEFCAG_02513 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LFDEFCAG_02514 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LFDEFCAG_02515 2.59e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
LFDEFCAG_02516 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
LFDEFCAG_02517 1.43e-124 dpsB - - P - - - Belongs to the Dps family
LFDEFCAG_02518 1.34e-26 - - - - - - - -
LFDEFCAG_02519 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
LFDEFCAG_02520 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
LFDEFCAG_02521 8.08e-184 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LFDEFCAG_02522 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
LFDEFCAG_02523 2.93e-234 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LFDEFCAG_02524 3.55e-164 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
LFDEFCAG_02525 4.16e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LFDEFCAG_02526 8.37e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
LFDEFCAG_02527 6.25e-132 - - - K - - - transcriptional regulator
LFDEFCAG_02528 1.13e-204 - - - S ko:K07045 - ko00000 Amidohydrolase
LFDEFCAG_02529 1.22e-68 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
LFDEFCAG_02530 8.86e-139 - - - - - - - -
LFDEFCAG_02532 9.96e-82 - - - - - - - -
LFDEFCAG_02533 6.18e-71 - - - - - - - -
LFDEFCAG_02534 2.04e-107 - - - M - - - PFAM NLP P60 protein
LFDEFCAG_02535 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
LFDEFCAG_02536 4.45e-38 - - - - - - - -
LFDEFCAG_02537 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
LFDEFCAG_02538 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
LFDEFCAG_02539 5.33e-114 - - - K - - - Winged helix DNA-binding domain
LFDEFCAG_02540 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
LFDEFCAG_02541 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
LFDEFCAG_02542 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
LFDEFCAG_02543 0.0 - - - - - - - -
LFDEFCAG_02544 2.41e-212 - - - S - - - Protein of unknown function (DUF1002)
LFDEFCAG_02545 1.58e-66 - - - - - - - -
LFDEFCAG_02546 9.19e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
LFDEFCAG_02547 5.94e-118 ymdB - - S - - - Macro domain protein
LFDEFCAG_02548 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LFDEFCAG_02549 1.05e-56 - - - S - - - Protein of unknown function (DUF1093)
LFDEFCAG_02550 2.93e-102 - - - S - - - Threonine/Serine exporter, ThrE
LFDEFCAG_02551 2.57e-171 - - - S - - - Putative threonine/serine exporter
LFDEFCAG_02552 1.36e-209 yvgN - - C - - - Aldo keto reductase
LFDEFCAG_02553 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LFDEFCAG_02554 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LFDEFCAG_02555 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
LFDEFCAG_02556 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
LFDEFCAG_02557 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
LFDEFCAG_02558 1.34e-229 ybcH - - D ko:K06889 - ko00000 Alpha beta
LFDEFCAG_02559 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LFDEFCAG_02560 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
LFDEFCAG_02561 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
LFDEFCAG_02562 4.39e-66 - - - - - - - -
LFDEFCAG_02563 7.21e-35 - - - - - - - -
LFDEFCAG_02564 8.8e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
LFDEFCAG_02565 2.07e-97 - - - S - - - COG NOG18757 non supervised orthologous group
LFDEFCAG_02566 4.26e-54 - - - - - - - -
LFDEFCAG_02567 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
LFDEFCAG_02568 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LFDEFCAG_02569 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LFDEFCAG_02570 1.47e-144 - - - S - - - VIT family
LFDEFCAG_02571 2.66e-155 - - - S - - - membrane
LFDEFCAG_02572 3.29e-203 - - - EG - - - EamA-like transporter family
LFDEFCAG_02573 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
LFDEFCAG_02574 3.57e-150 - - - GM - - - NmrA-like family
LFDEFCAG_02575 4.79e-21 - - - - - - - -
LFDEFCAG_02576 2.27e-74 - - - - - - - -
LFDEFCAG_02577 3.22e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LFDEFCAG_02578 1.36e-112 - - - - - - - -
LFDEFCAG_02579 2.11e-82 - - - - - - - -
LFDEFCAG_02580 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
LFDEFCAG_02581 1.7e-70 - - - - - - - -
LFDEFCAG_02582 1.41e-86 yeaO - - S - - - Protein of unknown function, DUF488
LFDEFCAG_02583 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
LFDEFCAG_02584 2.14e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
LFDEFCAG_02585 2.67e-189 - - - GM - - - NmrA-like family
LFDEFCAG_02586 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
LFDEFCAG_02587 5e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LFDEFCAG_02588 9.04e-317 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LFDEFCAG_02589 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LFDEFCAG_02590 3.58e-36 - - - S - - - Belongs to the LOG family
LFDEFCAG_02591 7.12e-256 glmS2 - - M - - - SIS domain
LFDEFCAG_02592 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LFDEFCAG_02593 9.53e-285 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
LFDEFCAG_02594 1.08e-82 - - - S - - - YjbR
LFDEFCAG_02596 0.0 cadA - - P - - - P-type ATPase
LFDEFCAG_02597 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
LFDEFCAG_02598 1.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LFDEFCAG_02599 4.29e-101 - - - - - - - -
LFDEFCAG_02600 4.9e-49 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
LFDEFCAG_02601 2.42e-127 - - - FG - - - HIT domain
LFDEFCAG_02602 1.05e-223 ydhF - - S - - - Aldo keto reductase
LFDEFCAG_02603 8.93e-71 - - - S - - - Pfam:DUF59
LFDEFCAG_02604 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LFDEFCAG_02605 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
LFDEFCAG_02606 1.87e-249 - - - V - - - Beta-lactamase
LFDEFCAG_02607 6.21e-124 - - - V - - - VanZ like family
LFDEFCAG_02608 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LFDEFCAG_02609 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
LFDEFCAG_02610 1.22e-292 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LFDEFCAG_02611 1.88e-291 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LFDEFCAG_02612 1.77e-240 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LFDEFCAG_02613 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LFDEFCAG_02614 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LFDEFCAG_02615 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LFDEFCAG_02616 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
LFDEFCAG_02617 5.6e-41 - - - - - - - -
LFDEFCAG_02618 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
LFDEFCAG_02619 2.5e-132 - - - L - - - Integrase
LFDEFCAG_02620 3.4e-85 - - - K - - - Winged helix DNA-binding domain
LFDEFCAG_02621 1.36e-84 - - - S - - - Cupredoxin-like domain
LFDEFCAG_02622 1.23e-57 - - - S - - - Cupredoxin-like domain
LFDEFCAG_02623 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LFDEFCAG_02624 6.8e-272 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
LFDEFCAG_02625 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
LFDEFCAG_02626 1.67e-86 lysM - - M - - - LysM domain
LFDEFCAG_02627 0.0 - - - E - - - Amino Acid
LFDEFCAG_02628 3.51e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
LFDEFCAG_02629 9.38e-91 - - - - - - - -
LFDEFCAG_02631 2.43e-208 yhxD - - IQ - - - KR domain
LFDEFCAG_02632 2.77e-291 amd - - E - - - Peptidase family M20/M25/M40
LFDEFCAG_02633 1.3e-226 - - - O - - - protein import
LFDEFCAG_02634 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02635 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_02636 2.31e-277 - - - - - - - -
LFDEFCAG_02637 3.41e-151 - - - GM - - - NAD(P)H-binding
LFDEFCAG_02638 3.83e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
LFDEFCAG_02639 3.55e-79 - - - I - - - sulfurtransferase activity
LFDEFCAG_02640 6.7e-102 yphH - - S - - - Cupin domain
LFDEFCAG_02641 1.17e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
LFDEFCAG_02642 2.51e-150 - - - GM - - - NAD(P)H-binding
LFDEFCAG_02643 1.88e-222 - - - C - - - C4-dicarboxylate transmembrane transporter activity
LFDEFCAG_02644 2.19e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LFDEFCAG_02645 3.05e-95 - - - - - - - -
LFDEFCAG_02646 5.78e-215 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
LFDEFCAG_02647 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
LFDEFCAG_02648 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
LFDEFCAG_02649 3.55e-281 - - - T - - - diguanylate cyclase
LFDEFCAG_02650 2.72e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
LFDEFCAG_02651 8.76e-121 - - - - - - - -
LFDEFCAG_02652 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LFDEFCAG_02653 1.58e-72 nudA - - S - - - ASCH
LFDEFCAG_02654 1.99e-138 - - - S - - - SdpI/YhfL protein family
LFDEFCAG_02655 1.18e-127 - - - M - - - Lysin motif
LFDEFCAG_02656 1.46e-97 - - - M - - - LysM domain
LFDEFCAG_02657 2.55e-100 - - - K - - - helix_turn_helix, mercury resistance
LFDEFCAG_02658 6.14e-235 - - - GM - - - Male sterility protein
LFDEFCAG_02659 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LFDEFCAG_02660 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_02661 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LFDEFCAG_02662 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LFDEFCAG_02663 1.24e-194 - - - K - - - Helix-turn-helix domain
LFDEFCAG_02664 1.21e-73 - - - - - - - -
LFDEFCAG_02665 7.85e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
LFDEFCAG_02666 2.03e-84 - - - - - - - -
LFDEFCAG_02667 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
LFDEFCAG_02668 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02669 7.89e-124 - - - P - - - Cadmium resistance transporter
LFDEFCAG_02670 1e-63 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
LFDEFCAG_02671 1.81e-150 - - - S - - - SNARE associated Golgi protein
LFDEFCAG_02672 7.03e-62 - - - - - - - -
LFDEFCAG_02673 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
LFDEFCAG_02674 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LFDEFCAG_02675 1.69e-158 - - - K - - - Helix-turn-helix XRE-family like proteins
LFDEFCAG_02676 2.88e-106 gtcA3 - - S - - - GtrA-like protein
LFDEFCAG_02677 2.93e-169 zmp3 - - O - - - Zinc-dependent metalloprotease
LFDEFCAG_02678 1.15e-43 - - - - - - - -
LFDEFCAG_02680 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
LFDEFCAG_02681 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
LFDEFCAG_02682 1.88e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
LFDEFCAG_02683 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
LFDEFCAG_02684 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_02685 1.67e-49 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LFDEFCAG_02686 3.67e-72 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LFDEFCAG_02687 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
LFDEFCAG_02688 7.52e-240 - - - S - - - Cell surface protein
LFDEFCAG_02689 1.4e-82 - - - - - - - -
LFDEFCAG_02690 0.0 - - - - - - - -
LFDEFCAG_02691 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_02692 6.48e-195 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LFDEFCAG_02693 7.52e-139 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LFDEFCAG_02694 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
LFDEFCAG_02695 8.08e-154 ydgI3 - - C - - - Nitroreductase family
LFDEFCAG_02696 5.24e-124 - - - K - - - Transcriptional regulator, MarR family
LFDEFCAG_02697 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LFDEFCAG_02698 7.52e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
LFDEFCAG_02699 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
LFDEFCAG_02700 2.51e-145 - - - K - - - Transcriptional regulator C-terminal region
LFDEFCAG_02701 4.12e-226 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
LFDEFCAG_02702 1.24e-165 - - - E - - - lipolytic protein G-D-S-L family
LFDEFCAG_02703 4e-205 yicL - - EG - - - EamA-like transporter family
LFDEFCAG_02704 1.21e-298 - - - M - - - Collagen binding domain
LFDEFCAG_02705 0.0 - - - I - - - acetylesterase activity
LFDEFCAG_02706 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LFDEFCAG_02707 3.49e-170 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
LFDEFCAG_02708 4.29e-50 - - - - - - - -
LFDEFCAG_02710 1.37e-182 - - - S - - - zinc-ribbon domain
LFDEFCAG_02711 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LFDEFCAG_02712 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
LFDEFCAG_02713 1.24e-313 - - - P - - - Sodium:sulfate symporter transmembrane region
LFDEFCAG_02714 5.12e-212 - - - K - - - LysR substrate binding domain
LFDEFCAG_02715 5.13e-129 - - - - - - - -
LFDEFCAG_02716 3.7e-30 - - - - - - - -
LFDEFCAG_02717 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LFDEFCAG_02718 6.48e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LFDEFCAG_02719 8.48e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
LFDEFCAG_02720 3.68e-107 - - - - - - - -
LFDEFCAG_02721 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
LFDEFCAG_02722 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LFDEFCAG_02723 3.29e-162 - - - T - - - Putative diguanylate phosphodiesterase
LFDEFCAG_02724 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
LFDEFCAG_02725 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LFDEFCAG_02726 2e-52 - - - S - - - Cytochrome B5
LFDEFCAG_02727 0.0 - - - - - - - -
LFDEFCAG_02728 2.39e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LFDEFCAG_02729 6.45e-203 - - - I - - - alpha/beta hydrolase fold
LFDEFCAG_02730 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
LFDEFCAG_02731 2.83e-297 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
LFDEFCAG_02732 2.67e-220 ropB - - K - - - Helix-turn-helix XRE-family like proteins
LFDEFCAG_02733 3.31e-265 - - - EGP - - - Major facilitator Superfamily
LFDEFCAG_02734 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
LFDEFCAG_02735 0.0 - - - S - - - Predicted membrane protein (DUF2207)
LFDEFCAG_02736 4.68e-190 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LFDEFCAG_02737 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
LFDEFCAG_02738 9.53e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LFDEFCAG_02739 1.48e-167 - - - M - - - Phosphotransferase enzyme family
LFDEFCAG_02740 8.42e-124 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LFDEFCAG_02741 2.81e-134 yokL3 - - J - - - Acetyltransferase (GNAT) domain
LFDEFCAG_02742 1.36e-198 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
LFDEFCAG_02743 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LFDEFCAG_02744 8.85e-141 - - - K - - - Transcriptional regulator (TetR family)
LFDEFCAG_02745 1.58e-230 yhgE - - V ko:K01421 - ko00000 domain protein
LFDEFCAG_02748 4.51e-314 - - - EGP - - - Major Facilitator
LFDEFCAG_02749 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_02750 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LFDEFCAG_02752 1.8e-249 - - - C - - - Aldo/keto reductase family
LFDEFCAG_02753 1.86e-132 - - - M - - - Protein of unknown function (DUF3737)
LFDEFCAG_02754 2.17e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LFDEFCAG_02755 5.52e-133 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
LFDEFCAG_02756 2.97e-82 - - - - - - - -
LFDEFCAG_02757 7.47e-164 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LFDEFCAG_02758 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
LFDEFCAG_02759 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
LFDEFCAG_02760 2.21e-46 - - - - - - - -
LFDEFCAG_02761 3.38e-193 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LFDEFCAG_02762 1.94e-246 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LFDEFCAG_02763 1.64e-130 - - - GM - - - NAD(P)H-binding
LFDEFCAG_02764 1.83e-201 - - - K - - - LysR substrate binding domain
LFDEFCAG_02765 2.65e-78 - - - S - - - Domain of unknown function (DUF4440)
LFDEFCAG_02766 1.1e-144 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
LFDEFCAG_02767 2.81e-64 - - - - - - - -
LFDEFCAG_02768 2.8e-49 - - - - - - - -
LFDEFCAG_02769 6.25e-112 yvbK - - K - - - GNAT family
LFDEFCAG_02770 8.4e-112 - - - - - - - -
LFDEFCAG_02771 3.19e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LFDEFCAG_02772 5.98e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LFDEFCAG_02773 1.24e-138 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LFDEFCAG_02774 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LFDEFCAG_02776 1.74e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02777 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LFDEFCAG_02778 1.46e-299 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LFDEFCAG_02779 7.37e-103 - - - K - - - transcriptional regulator, MerR family
LFDEFCAG_02780 2.27e-98 yphH - - S - - - Cupin domain
LFDEFCAG_02781 1.16e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LFDEFCAG_02782 3.63e-165 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LFDEFCAG_02783 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LFDEFCAG_02784 4.23e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02785 1.6e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
LFDEFCAG_02786 4.96e-88 - - - M - - - LysM domain
LFDEFCAG_02788 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LFDEFCAG_02789 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
LFDEFCAG_02790 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LFDEFCAG_02791 4.38e-222 - - - S - - - Conserved hypothetical protein 698
LFDEFCAG_02792 8.99e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LFDEFCAG_02793 4.03e-104 - - - S - - - Domain of unknown function (DUF4811)
LFDEFCAG_02794 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
LFDEFCAG_02795 7.22e-163 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LFDEFCAG_02796 3.04e-261 - - - EGP - - - Major Facilitator Superfamily
LFDEFCAG_02797 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
LFDEFCAG_02798 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
LFDEFCAG_02799 9.01e-155 - - - S - - - Membrane
LFDEFCAG_02800 1.97e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LFDEFCAG_02801 3.55e-127 ywjB - - H - - - RibD C-terminal domain
LFDEFCAG_02802 2e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
LFDEFCAG_02803 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
LFDEFCAG_02804 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02805 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LFDEFCAG_02806 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
LFDEFCAG_02807 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LFDEFCAG_02808 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
LFDEFCAG_02809 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LFDEFCAG_02810 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
LFDEFCAG_02811 3.84e-185 - - - S - - - Peptidase_C39 like family
LFDEFCAG_02812 7.58e-244 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
LFDEFCAG_02813 1.27e-143 - - - - - - - -
LFDEFCAG_02814 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LFDEFCAG_02815 1.97e-110 - - - S - - - Pfam:DUF3816
LFDEFCAG_02816 3.2e-13 - - - Q - - - HAD-superfamily phosphatase subfamily IIIC
LFDEFCAG_02817 7.01e-83 - - - S - - - Capsule biosynthesis phosphatase
LFDEFCAG_02818 0.0 - - - JM - - - COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LFDEFCAG_02819 2.67e-165 - - - M - - - COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LFDEFCAG_02821 1.8e-109 - 3.2.1.82 GH28 E ko:K18650 - ko00000,ko01000 lipolytic protein G-D-S-L family
LFDEFCAG_02822 2.67e-48 cps3J - - M - - - Domain of unknown function (DUF4422)
LFDEFCAG_02825 0.0 - - - S ko:K07484 - ko00000 Transposase IS66 family
LFDEFCAG_02826 5.49e-82 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
LFDEFCAG_02827 3.97e-77 - - - L ko:K07483 - ko00000 Transposase
LFDEFCAG_02828 0.0 - - - M - - - domain protein
LFDEFCAG_02829 2.5e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LFDEFCAG_02830 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
LFDEFCAG_02831 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LFDEFCAG_02832 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
LFDEFCAG_02833 1.1e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02834 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LFDEFCAG_02835 2.01e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
LFDEFCAG_02836 2.18e-168 epsB - - M - - - biosynthesis protein
LFDEFCAG_02837 2.27e-161 ywqD - - D - - - Capsular exopolysaccharide family
LFDEFCAG_02838 1.97e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LFDEFCAG_02839 1.33e-226 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
LFDEFCAG_02840 8.38e-160 tuaA - - M - - - Bacterial sugar transferase
LFDEFCAG_02841 1.47e-166 cps4F - - M - - - Glycosyl transferases group 1
LFDEFCAG_02842 1.54e-159 cps4G - - M - - - Glycosyltransferase Family 4
LFDEFCAG_02843 2.08e-218 - - - - - - - -
LFDEFCAG_02844 2.08e-167 cps4I - - M - - - Glycosyltransferase like family 2
LFDEFCAG_02845 1.13e-56 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
LFDEFCAG_02846 2.34e-105 cps2J - - S - - - Polysaccharide biosynthesis protein
LFDEFCAG_02847 1e-28 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
LFDEFCAG_02848 1.86e-175 - - - M - - - domain protein
LFDEFCAG_02849 1.44e-228 - - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
LFDEFCAG_02850 1.6e-220 - - - C - - - Alcohol dehydrogenase GroES-like domain
LFDEFCAG_02851 7.45e-108 - - - S - - - Haem-degrading
LFDEFCAG_02852 1.87e-246 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LFDEFCAG_02853 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LFDEFCAG_02854 2.2e-250 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LFDEFCAG_02855 3.39e-226 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LFDEFCAG_02856 2.4e-258 iolG 1.1.1.18, 1.1.1.369 - C ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LFDEFCAG_02857 5.84e-252 iolG2 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LFDEFCAG_02858 0.0 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LFDEFCAG_02859 3.1e-138 - - - L - - - Integrase
LFDEFCAG_02860 4.17e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
LFDEFCAG_02861 1.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
LFDEFCAG_02862 0.000343 - - - S - - - Protein of unknown function (DUF3923)
LFDEFCAG_02863 9.28e-22 - - - K - - - Helix-turn-helix domain
LFDEFCAG_02864 8e-177 - - - K - - - Helix-turn-helix domain
LFDEFCAG_02865 8.58e-71 - - - K - - - Helix-turn-helix XRE-family like proteins
LFDEFCAG_02866 1.26e-74 - - - S - - - Protein of unknown function (DUF2992)
LFDEFCAG_02867 1.46e-37 - - - - - - - -
LFDEFCAG_02871 6.94e-37 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
LFDEFCAG_02872 4.56e-85 - - - L - - - Transposase
LFDEFCAG_02873 1.31e-288 - - - L - - - MULE transposase domain
LFDEFCAG_02874 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
LFDEFCAG_02875 2.17e-131 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
LFDEFCAG_02876 2.31e-48 - - - K - - - LysR substrate binding domain
LFDEFCAG_02877 9.15e-91 - - - KT - - - Purine catabolism regulatory protein-like family
LFDEFCAG_02878 1.08e-165 hyuA - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
LFDEFCAG_02879 7.59e-288 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
LFDEFCAG_02880 1.59e-61 - - - - - - - -
LFDEFCAG_02881 1.33e-77 - - - - - - - -
LFDEFCAG_02883 1.07e-208 - - - K - - - Transcriptional regulator
LFDEFCAG_02884 2.95e-207 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
LFDEFCAG_02885 1.42e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
LFDEFCAG_02886 2.45e-101 - - - K - - - Winged helix DNA-binding domain
LFDEFCAG_02887 0.0 ycaM - - E - - - amino acid
LFDEFCAG_02888 2.55e-166 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
LFDEFCAG_02889 4.3e-44 - - - - - - - -
LFDEFCAG_02890 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
LFDEFCAG_02891 0.0 - - - M - - - Domain of unknown function (DUF5011)
LFDEFCAG_02892 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
LFDEFCAG_02893 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
LFDEFCAG_02894 3.1e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
LFDEFCAG_02895 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
LFDEFCAG_02896 2.8e-204 - - - EG - - - EamA-like transporter family
LFDEFCAG_02897 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LFDEFCAG_02898 5.06e-196 - - - S - - - hydrolase
LFDEFCAG_02899 7.63e-107 - - - - - - - -
LFDEFCAG_02900 7.15e-156 pgm7 - - G - - - Phosphoglycerate mutase family
LFDEFCAG_02901 1.4e-181 epsV - - S - - - glycosyl transferase family 2
LFDEFCAG_02902 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
LFDEFCAG_02903 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LFDEFCAG_02904 2.73e-73 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
LFDEFCAG_02905 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LFDEFCAG_02906 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LFDEFCAG_02907 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
LFDEFCAG_02908 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LFDEFCAG_02909 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_02910 2.13e-152 - - - K - - - Transcriptional regulator
LFDEFCAG_02911 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LFDEFCAG_02912 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
LFDEFCAG_02913 1.48e-292 - - - S - - - Sterol carrier protein domain
LFDEFCAG_02914 3.48e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
LFDEFCAG_02915 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
LFDEFCAG_02916 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LFDEFCAG_02917 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
LFDEFCAG_02918 2.28e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LFDEFCAG_02919 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LFDEFCAG_02920 2.96e-41 - - - S - - - Pentapeptide repeats (8 copies)
LFDEFCAG_02921 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LFDEFCAG_02922 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
LFDEFCAG_02923 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LFDEFCAG_02925 1.21e-69 - - - - - - - -
LFDEFCAG_02926 1.52e-151 - - - - - - - -
LFDEFCAG_02927 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
LFDEFCAG_02928 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LFDEFCAG_02929 4.79e-13 - - - - - - - -
LFDEFCAG_02930 1.4e-65 - - - - - - - -
LFDEFCAG_02931 1.02e-113 - - - - - - - -
LFDEFCAG_02932 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
LFDEFCAG_02933 8.93e-47 - - - - - - - -
LFDEFCAG_02934 2.7e-104 usp5 - - T - - - universal stress protein
LFDEFCAG_02935 3.41e-190 - - - - - - - -
LFDEFCAG_02936 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02937 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
LFDEFCAG_02938 4.76e-56 - - - - - - - -
LFDEFCAG_02939 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
LFDEFCAG_02940 3.4e-177 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_02941 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
LFDEFCAG_02942 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LFDEFCAG_02943 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
LFDEFCAG_02944 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LFDEFCAG_02945 1.16e-242 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
LFDEFCAG_02946 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
LFDEFCAG_02947 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
LFDEFCAG_02948 8.89e-103 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LFDEFCAG_02949 1.37e-268 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LFDEFCAG_02950 3.95e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LFDEFCAG_02951 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LFDEFCAG_02952 2.82e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LFDEFCAG_02953 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LFDEFCAG_02954 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LFDEFCAG_02955 1.72e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LFDEFCAG_02956 1.79e-131 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LFDEFCAG_02957 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LFDEFCAG_02958 2.71e-280 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LFDEFCAG_02959 9.07e-158 - - - E - - - Methionine synthase
LFDEFCAG_02960 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
LFDEFCAG_02961 2.62e-121 - - - - - - - -
LFDEFCAG_02962 1.77e-199 - - - T - - - EAL domain
LFDEFCAG_02963 4.71e-208 - - - GM - - - NmrA-like family
LFDEFCAG_02964 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
LFDEFCAG_02965 4.41e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
LFDEFCAG_02966 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
LFDEFCAG_02967 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LFDEFCAG_02968 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LFDEFCAG_02969 3.38e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LFDEFCAG_02970 3.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LFDEFCAG_02971 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LFDEFCAG_02972 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LFDEFCAG_02973 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LFDEFCAG_02974 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LFDEFCAG_02975 1.56e-217 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
LFDEFCAG_02976 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LFDEFCAG_02977 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LFDEFCAG_02978 1.57e-123 - - - K - - - Acetyltransferase (GNAT) family
LFDEFCAG_02979 1.29e-148 - - - GM - - - NAD(P)H-binding
LFDEFCAG_02980 8.13e-208 mleR - - K - - - LysR family
LFDEFCAG_02981 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
LFDEFCAG_02982 3.59e-26 - - - - - - - -
LFDEFCAG_02983 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LFDEFCAG_02984 1.02e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LFDEFCAG_02985 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
LFDEFCAG_02986 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LFDEFCAG_02987 4.71e-74 - - - S - - - SdpI/YhfL protein family
LFDEFCAG_02988 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
LFDEFCAG_02989 2.84e-82 - - - K - - - helix_turn_helix, mercury resistance
LFDEFCAG_02990 1.17e-270 yttB - - EGP - - - Major Facilitator
LFDEFCAG_02991 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
LFDEFCAG_02992 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
LFDEFCAG_02993 0.0 yhdP - - S - - - Transporter associated domain
LFDEFCAG_02994 2.97e-76 - - - - - - - -
LFDEFCAG_02995 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LFDEFCAG_02996 2.2e-79 - - - - - - - -
LFDEFCAG_02997 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
LFDEFCAG_02998 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
LFDEFCAG_02999 4.85e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LFDEFCAG_03000 6.08e-179 - - - - - - - -
LFDEFCAG_03001 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LFDEFCAG_03002 3.53e-169 - - - K - - - Transcriptional regulator
LFDEFCAG_03003 1.52e-204 - - - S - - - Putative esterase
LFDEFCAG_03004 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LFDEFCAG_03005 1.03e-282 - - - M - - - Glycosyl transferases group 1
LFDEFCAG_03006 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
LFDEFCAG_03007 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
LFDEFCAG_03008 1.84e-205 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LFDEFCAG_03009 2.51e-103 uspA3 - - T - - - universal stress protein
LFDEFCAG_03010 5.87e-166 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LFDEFCAG_03011 4.28e-112 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LFDEFCAG_03012 5.2e-185 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LFDEFCAG_03013 3.82e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
LFDEFCAG_03014 1.63e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LFDEFCAG_03015 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
LFDEFCAG_03016 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LFDEFCAG_03017 4.15e-78 - - - - - - - -
LFDEFCAG_03018 4.05e-98 - - - - - - - -
LFDEFCAG_03019 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
LFDEFCAG_03020 1.57e-71 - - - - - - - -
LFDEFCAG_03021 3.89e-62 - - - - - - - -
LFDEFCAG_03022 3.87e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
LFDEFCAG_03023 9.89e-74 ytpP - - CO - - - Thioredoxin
LFDEFCAG_03024 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
LFDEFCAG_03025 4.27e-89 - - - - - - - -
LFDEFCAG_03026 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LFDEFCAG_03027 4.83e-64 - - - - - - - -
LFDEFCAG_03028 1.28e-77 - - - - - - - -
LFDEFCAG_03029 1.86e-210 - - - - - - - -
LFDEFCAG_03030 1.4e-95 - - - K - - - Transcriptional regulator
LFDEFCAG_03031 0.0 pepF2 - - E - - - Oligopeptidase F
LFDEFCAG_03032 2.29e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
LFDEFCAG_03033 7.2e-61 - - - S - - - Enterocin A Immunity
LFDEFCAG_03034 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
LFDEFCAG_03035 5.83e-161 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LFDEFCAG_03036 2.66e-172 - - - - - - - -
LFDEFCAG_03037 9.38e-139 pncA - - Q - - - Isochorismatase family
LFDEFCAG_03038 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LFDEFCAG_03039 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
LFDEFCAG_03040 1.89e-254 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
LFDEFCAG_03041 3.02e-228 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LFDEFCAG_03042 6.43e-204 - - - K - - - Helix-turn-helix domain, rpiR family
LFDEFCAG_03043 2.89e-224 ccpB - - K - - - lacI family
LFDEFCAG_03044 2.13e-182 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LFDEFCAG_03045 2.11e-159 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
LFDEFCAG_03046 4.3e-228 - - - K - - - sugar-binding domain protein
LFDEFCAG_03047 0.0 pflD 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
LFDEFCAG_03048 2.48e-174 rdrA - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LFDEFCAG_03049 2.08e-199 - 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LFDEFCAG_03050 3.16e-232 - - - GK - - - ROK family
LFDEFCAG_03051 3.3e-199 - - - U ko:K05340 - ko00000,ko02000 sugar transport
LFDEFCAG_03052 1.41e-208 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LFDEFCAG_03053 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
LFDEFCAG_03054 6.05e-127 - - - C - - - Nitroreductase family
LFDEFCAG_03055 7.05e-216 - - - S - - - Polyphosphate kinase 2 (PPK2)
LFDEFCAG_03057 1.71e-31 - - - - - - - -
LFDEFCAG_03058 5.05e-99 - - - - - - - -
LFDEFCAG_03059 1.6e-37 - - - - - - - -
LFDEFCAG_03060 3.24e-27 - - - S - - - Mor transcription activator family
LFDEFCAG_03064 1.83e-236 adhP 1.1.1.1 - C ko:K13953,ko:K13979 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LFDEFCAG_03065 6.5e-185 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
LFDEFCAG_03067 3.73e-85 - - - D ko:K03496 - ko00000,ko03036,ko04812 VirC1 protein
LFDEFCAG_03068 8.14e-63 - - - K ko:K07726 - ko00000,ko03000 transcriptional regulator
LFDEFCAG_03069 9.65e-60 - - - S - - - Cytotoxic translational repressor of toxin-antitoxin stability system
LFDEFCAG_03070 3.06e-237 - - - U - - - Adhesin family
LFDEFCAG_03071 2.79e-114 - - - - - - - -
LFDEFCAG_03072 7.95e-34 - - - - - - - -
LFDEFCAG_03073 1.92e-54 yefM - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
LFDEFCAG_03074 6.83e-133 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
LFDEFCAG_03075 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LFDEFCAG_03076 3.04e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
LFDEFCAG_03077 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
LFDEFCAG_03078 6.71e-284 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LFDEFCAG_03079 1.31e-119 - - - K - - - Periplasmic binding proteins and sugar binding domain of LacI family
LFDEFCAG_03080 3.79e-85 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LFDEFCAG_03081 4.54e-132 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LFDEFCAG_03082 5.82e-139 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
LFDEFCAG_03083 3.43e-55 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LFDEFCAG_03084 1.19e-289 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LFDEFCAG_03085 1.27e-219 - - - L - - - Belongs to the 'phage' integrase family
LFDEFCAG_03086 1.23e-67 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
LFDEFCAG_03087 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LFDEFCAG_03088 1.67e-304 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
LFDEFCAG_03089 1.88e-23 - - - - - - - -
LFDEFCAG_03090 2.35e-46 - - - S - - - protein conserved in bacteria
LFDEFCAG_03091 6.52e-36 - - - - - - - -
LFDEFCAG_03092 0.0 traA - - L - - - MobA MobL family protein
LFDEFCAG_03093 6.51e-48 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
LFDEFCAG_03094 2.09e-85 - - - - - - - -
LFDEFCAG_03095 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LFDEFCAG_03096 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LFDEFCAG_03097 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
LFDEFCAG_03098 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LFDEFCAG_03099 3.88e-147 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
LFDEFCAG_03100 4.87e-166 ycsI - - S - - - Protein of unknown function (DUF1445)
LFDEFCAG_03101 2.91e-140 - - - S ko:K07160 - ko00000 LamB/YcsF family
LFDEFCAG_03102 8.53e-234 ycsG - - P - - - Natural resistance-associated macrophage protein
LFDEFCAG_03103 3.64e-45 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LFDEFCAG_03104 4.41e-59 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
LFDEFCAG_03105 3.57e-58 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LFDEFCAG_03106 3.38e-294 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
LFDEFCAG_03108 2.55e-51 - - - S - - - Bacteriophage holin
LFDEFCAG_03109 8.8e-48 - - - S - - - Haemolysin XhlA
LFDEFCAG_03110 1.16e-223 - - - M - - - Glycosyl hydrolases family 25
LFDEFCAG_03111 3.02e-72 - - - - - - - -
LFDEFCAG_03115 0.0 - - - S - - - Phage minor structural protein
LFDEFCAG_03116 1.17e-285 - - - S - - - Phage tail protein
LFDEFCAG_03117 0.0 - - - D - - - domain protein
LFDEFCAG_03118 2.09e-26 - - - - - - - -
LFDEFCAG_03119 3.88e-75 - - - S - - - Phage tail assembly chaperone proteins, TAC
LFDEFCAG_03120 1.42e-138 - - - S - - - Phage tail tube protein
LFDEFCAG_03121 7.78e-76 - - - S - - - Protein of unknown function (DUF806)
LFDEFCAG_03122 6.72e-88 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LFDEFCAG_03123 2.73e-73 - - - S - - - Phage head-tail joining protein
LFDEFCAG_03124 5.64e-66 - - - S - - - Phage gp6-like head-tail connector protein
LFDEFCAG_03125 7.01e-270 - - - S - - - Phage capsid family
LFDEFCAG_03126 1.53e-159 - - - S - - - Clp protease
LFDEFCAG_03127 4.21e-285 - - - S - - - Phage portal protein
LFDEFCAG_03128 1.64e-35 - - - S - - - Protein of unknown function (DUF1056)
LFDEFCAG_03129 0.0 - - - S - - - Phage Terminase
LFDEFCAG_03130 5.28e-100 - - - L - - - Phage terminase, small subunit
LFDEFCAG_03131 7.03e-40 - - - S - - - HNH endonuclease
LFDEFCAG_03132 8.47e-109 - - - L - - - HNH nucleases
LFDEFCAG_03133 4.32e-20 - - - - - - - -
LFDEFCAG_03134 1.02e-16 - - - - - - - -
LFDEFCAG_03135 4.87e-100 - - - S - - - Transcriptional regulator, RinA family
LFDEFCAG_03136 6.79e-27 - - - - - - - -
LFDEFCAG_03138 3.16e-12 - - - - - - - -
LFDEFCAG_03140 5.88e-20 - - - - - - - -
LFDEFCAG_03142 1.49e-59 - - - - - - - -
LFDEFCAG_03144 1.02e-187 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
LFDEFCAG_03145 3.06e-77 - - - L - - - DnaD domain protein
LFDEFCAG_03146 1.07e-14 - - - S - - - HNH endonuclease
LFDEFCAG_03149 1.12e-12 - - - - - - - -
LFDEFCAG_03158 2.27e-77 - - - S - - - ORF6C domain
LFDEFCAG_03160 3.49e-30 - - - K - - - Helix-turn-helix XRE-family like proteins
LFDEFCAG_03161 6.22e-48 - - - S - - - Pfam:Peptidase_M78
LFDEFCAG_03165 3.44e-74 int3 - - L - - - Belongs to the 'phage' integrase family
LFDEFCAG_03166 1.75e-43 - - - - - - - -
LFDEFCAG_03167 4.15e-183 - - - Q - - - Methyltransferase
LFDEFCAG_03168 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
LFDEFCAG_03169 1.17e-269 - - - EGP - - - Major facilitator Superfamily
LFDEFCAG_03170 4.57e-135 - - - K - - - Helix-turn-helix domain
LFDEFCAG_03171 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LFDEFCAG_03172 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LFDEFCAG_03173 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
LFDEFCAG_03174 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LFDEFCAG_03175 2.05e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LFDEFCAG_03176 6.62e-62 - - - - - - - -
LFDEFCAG_03177 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LFDEFCAG_03178 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
LFDEFCAG_03179 1.73e-217 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LFDEFCAG_03180 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
LFDEFCAG_03181 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
LFDEFCAG_03182 0.0 cps4J - - S - - - MatE
LFDEFCAG_03183 2.39e-228 cps4I - - M - - - Glycosyltransferase like family 2
LFDEFCAG_03184 1.01e-292 - - - - - - - -
LFDEFCAG_03185 5.46e-235 cps4G - - M - - - Glycosyltransferase Family 4
LFDEFCAG_03186 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
LFDEFCAG_03187 5.49e-163 tuaA - - M - - - Bacterial sugar transferase
LFDEFCAG_03188 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
LFDEFCAG_03189 2.25e-188 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LFDEFCAG_03190 4.97e-157 ywqD - - D - - - Capsular exopolysaccharide family
LFDEFCAG_03191 8.45e-162 epsB - - M - - - biosynthesis protein
LFDEFCAG_03192 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LFDEFCAG_03193 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LFDEFCAG_03194 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LFDEFCAG_03195 5.12e-31 - - - - - - - -
LFDEFCAG_03196 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
LFDEFCAG_03197 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
LFDEFCAG_03198 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LFDEFCAG_03199 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LFDEFCAG_03200 3.75e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LFDEFCAG_03201 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LFDEFCAG_03202 5.89e-204 - - - S - - - Tetratricopeptide repeat
LFDEFCAG_03203 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LFDEFCAG_03204 1.29e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LFDEFCAG_03205 3.84e-262 - - - EGP - - - Major Facilitator Superfamily
LFDEFCAG_03206 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LFDEFCAG_03207 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LFDEFCAG_03208 5.09e-241 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LFDEFCAG_03209 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LFDEFCAG_03210 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LFDEFCAG_03211 4.39e-51 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
LFDEFCAG_03212 2.16e-99 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
LFDEFCAG_03213 4.27e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LFDEFCAG_03214 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LFDEFCAG_03215 4.98e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
LFDEFCAG_03216 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
LFDEFCAG_03217 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LFDEFCAG_03218 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LFDEFCAG_03219 0.0 - - - - - - - -
LFDEFCAG_03220 0.0 icaA - - M - - - Glycosyl transferase family group 2
LFDEFCAG_03221 9.51e-135 - - - - - - - -
LFDEFCAG_03222 1.1e-257 - - - - - - - -
LFDEFCAG_03223 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LFDEFCAG_03224 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
LFDEFCAG_03225 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
LFDEFCAG_03226 2.51e-208 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
LFDEFCAG_03227 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
LFDEFCAG_03228 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LFDEFCAG_03229 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
LFDEFCAG_03230 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
LFDEFCAG_03231 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LFDEFCAG_03232 6.45e-111 - - - - - - - -
LFDEFCAG_03233 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
LFDEFCAG_03234 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LFDEFCAG_03235 1.71e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LFDEFCAG_03236 6.21e-39 - - - - - - - -
LFDEFCAG_03237 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
LFDEFCAG_03238 1.6e-221 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LFDEFCAG_03239 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LFDEFCAG_03240 1.02e-155 - - - S - - - repeat protein
LFDEFCAG_03241 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
LFDEFCAG_03242 0.0 - - - N - - - domain, Protein
LFDEFCAG_03243 1.22e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
LFDEFCAG_03244 3.57e-154 - - - N - - - WxL domain surface cell wall-binding
LFDEFCAG_03245 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
LFDEFCAG_03246 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
LFDEFCAG_03247 6.7e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LFDEFCAG_03248 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
LFDEFCAG_03249 1.06e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LFDEFCAG_03250 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LFDEFCAG_03251 7.74e-47 - - - - - - - -
LFDEFCAG_03252 2.8e-93 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LFDEFCAG_03253 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LFDEFCAG_03254 2.05e-20 - - - S - - - Protein of unknown function (DUF3021)
LFDEFCAG_03255 2.57e-47 - - - K - - - LytTr DNA-binding domain
LFDEFCAG_03256 1.47e-100 - - - U ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
LFDEFCAG_03257 4.02e-99 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
LFDEFCAG_03258 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LFDEFCAG_03259 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
LFDEFCAG_03260 3.41e-186 ylmH - - S - - - S4 domain protein
LFDEFCAG_03261 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
LFDEFCAG_03262 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LFDEFCAG_03263 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LFDEFCAG_03264 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LFDEFCAG_03265 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LFDEFCAG_03266 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LFDEFCAG_03267 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LFDEFCAG_03268 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LFDEFCAG_03269 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LFDEFCAG_03270 7.01e-76 ftsL - - D - - - Cell division protein FtsL
LFDEFCAG_03271 8.62e-225 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LFDEFCAG_03272 5.96e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LFDEFCAG_03273 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
LFDEFCAG_03274 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LFDEFCAG_03275 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LFDEFCAG_03276 5.75e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LFDEFCAG_03277 2.5e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
LFDEFCAG_03278 2.17e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LFDEFCAG_03280 3.74e-206 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
LFDEFCAG_03281 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LFDEFCAG_03282 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
LFDEFCAG_03283 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LFDEFCAG_03284 6.5e-246 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
LFDEFCAG_03285 7.21e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
LFDEFCAG_03286 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LFDEFCAG_03287 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LFDEFCAG_03288 3.7e-156 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LFDEFCAG_03289 2.24e-148 yjbH - - Q - - - Thioredoxin
LFDEFCAG_03290 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LFDEFCAG_03291 3.19e-264 coiA - - S ko:K06198 - ko00000 Competence protein
LFDEFCAG_03292 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LFDEFCAG_03293 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LFDEFCAG_03294 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
LFDEFCAG_03295 4.4e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)