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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HDGNIKPO_00001	8.95e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDGNIKPO_00002	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDGNIKPO_00003	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HDGNIKPO_00004	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDGNIKPO_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDGNIKPO_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDGNIKPO_00007	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HDGNIKPO_00008	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDGNIKPO_00009	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDGNIKPO_00010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HDGNIKPO_00011	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HDGNIKPO_00012	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HDGNIKPO_00013	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_00014	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDGNIKPO_00015	3.25e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDGNIKPO_00016	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDGNIKPO_00018	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDGNIKPO_00019	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDGNIKPO_00020	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HDGNIKPO_00021	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDGNIKPO_00022	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDGNIKPO_00023	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDGNIKPO_00025	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDGNIKPO_00026	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HDGNIKPO_00027	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HDGNIKPO_00028	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HDGNIKPO_00029	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HDGNIKPO_00030	2.54e-50	-	-	-	-	-	-	-	-
HDGNIKPO_00031	2.85e-290	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDGNIKPO_00032	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
HDGNIKPO_00034	4.64e-12	-	-	-	-	-	-	-	-
HDGNIKPO_00037	4.95e-177	-	-	-	L	-	-	-	DNA replication protein
HDGNIKPO_00038	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HDGNIKPO_00040	6.4e-97	-	-	-	-	-	-	-	-
HDGNIKPO_00042	1.79e-68	-	-	-	S	-	-	-	Head-tail joining protein
HDGNIKPO_00043	4.46e-90	-	-	-	L	-	-	-	HNH endonuclease
HDGNIKPO_00044	2.13e-106	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HDGNIKPO_00045	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HDGNIKPO_00046	0.000495	-	-	-	-	-	-	-	-
HDGNIKPO_00047	5.25e-257	-	-	-	S	-	-	-	Phage portal protein
HDGNIKPO_00048	1.25e-264	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HDGNIKPO_00051	2.58e-52	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDGNIKPO_00052	6.45e-70	-	-	-	-	-	-	-	-
HDGNIKPO_00053	1.72e-40	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HDGNIKPO_00054	9.46e-44	-	-	-	-	-	-	-	-
HDGNIKPO_00056	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDGNIKPO_00057	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDGNIKPO_00058	5.04e-313	yycH	-	-	S	-	-	-	YycH protein
HDGNIKPO_00059	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HDGNIKPO_00060	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HDGNIKPO_00061	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HDGNIKPO_00062	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDGNIKPO_00063	2e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_00064	6.44e-231	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HDGNIKPO_00065	6.34e-49	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HDGNIKPO_00066	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HDGNIKPO_00067	1.84e-154	pnb	-	-	C	-	-	-	nitroreductase
HDGNIKPO_00068	2.02e-85	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HDGNIKPO_00069	2.14e-148	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HDGNIKPO_00070	0.0	-	-	-	C	-	-	-	FMN_bind
HDGNIKPO_00071	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDGNIKPO_00072	3.43e-203	-	-	-	K	-	-	-	LysR family
HDGNIKPO_00073	1.69e-93	-	-	-	C	-	-	-	FMN binding
HDGNIKPO_00074	1.82e-97	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDGNIKPO_00075	3.34e-210	-	-	-	S	-	-	-	KR domain
HDGNIKPO_00076	9.51e-203	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HDGNIKPO_00077	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HDGNIKPO_00078	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HDGNIKPO_00079	2.22e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HDGNIKPO_00080	9.29e-250	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDGNIKPO_00081	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDGNIKPO_00082	2.79e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDGNIKPO_00083	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HDGNIKPO_00084	1.65e-106	-	-	-	S	-	-	-	ASCH
HDGNIKPO_00085	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HDGNIKPO_00086	1.88e-216	-	-	-	K	-	-	-	WYL domain
HDGNIKPO_00087	6.65e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDGNIKPO_00088	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HDGNIKPO_00089	3.66e-59	-	-	-	S	-	-	-	Protein of unknown function
HDGNIKPO_00090	2.84e-81	-	-	-	S	-	-	-	Protein of unknown function
HDGNIKPO_00091	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HDGNIKPO_00092	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HDGNIKPO_00093	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HDGNIKPO_00094	3.42e-234	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HDGNIKPO_00095	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDGNIKPO_00096	6.97e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HDGNIKPO_00097	2.02e-216	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HDGNIKPO_00098	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HDGNIKPO_00099	2.38e-99	-	-	-	-	-	-	-	-
HDGNIKPO_00100	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HDGNIKPO_00101	3.99e-179	-	-	-	-	-	-	-	-
HDGNIKPO_00102	4.07e-05	-	-	-	-	-	-	-	-
HDGNIKPO_00103	2.92e-186	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HDGNIKPO_00104	1.67e-54	-	-	-	-	-	-	-	-
HDGNIKPO_00105	7.41e-167	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_00106	8.38e-193	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HDGNIKPO_00107	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HDGNIKPO_00108	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HDGNIKPO_00109	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HDGNIKPO_00110	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HDGNIKPO_00111	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HDGNIKPO_00112	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HDGNIKPO_00113	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDGNIKPO_00114	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HDGNIKPO_00115	4.79e-225	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDGNIKPO_00116	2.27e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HDGNIKPO_00117	9.72e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HDGNIKPO_00118	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HDGNIKPO_00119	9.14e-265	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HDGNIKPO_00120	7.45e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HDGNIKPO_00121	0.0	-	-	-	L	-	-	-	HIRAN domain
HDGNIKPO_00122	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HDGNIKPO_00123	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HDGNIKPO_00124	8.96e-160	-	-	-	-	-	-	-	-
HDGNIKPO_00125	5.08e-192	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HDGNIKPO_00126	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HDGNIKPO_00127	1.29e-181	-	-	-	F	-	-	-	Phosphorylase superfamily
HDGNIKPO_00128	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HDGNIKPO_00129	5.13e-144	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HDGNIKPO_00130	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_00131	2.31e-95	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDGNIKPO_00132	2.14e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HDGNIKPO_00133	4.14e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
HDGNIKPO_00134	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HDGNIKPO_00135	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDGNIKPO_00136	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HDGNIKPO_00138	2.16e-204	morA	-	-	S	-	-	-	reductase
HDGNIKPO_00139	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HDGNIKPO_00140	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HDGNIKPO_00141	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HDGNIKPO_00142	4.03e-132	-	-	-	-	-	-	-	-
HDGNIKPO_00143	0.0	-	-	-	-	-	-	-	-
HDGNIKPO_00144	1.86e-267	-	-	-	C	-	-	-	Oxidoreductase
HDGNIKPO_00145	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HDGNIKPO_00146	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_00147	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HDGNIKPO_00148	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HDGNIKPO_00149	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HDGNIKPO_00150	7.71e-183	-	-	-	-	-	-	-	-
HDGNIKPO_00151	3.16e-191	-	-	-	-	-	-	-	-
HDGNIKPO_00152	3.37e-115	-	-	-	-	-	-	-	-
HDGNIKPO_00153	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HDGNIKPO_00154	1.04e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_00155	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HDGNIKPO_00156	9.77e-152	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HDGNIKPO_00157	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HDGNIKPO_00158	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HDGNIKPO_00160	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_00161	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HDGNIKPO_00162	9.52e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HDGNIKPO_00163	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HDGNIKPO_00164	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HDGNIKPO_00165	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDGNIKPO_00166	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDGNIKPO_00167	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HDGNIKPO_00168	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HDGNIKPO_00169	4.69e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDGNIKPO_00170	2.16e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDGNIKPO_00171	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_00172	1.75e-191	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HDGNIKPO_00173	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HDGNIKPO_00174	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDGNIKPO_00175	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDGNIKPO_00176	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HDGNIKPO_00177	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HDGNIKPO_00178	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HDGNIKPO_00179	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDGNIKPO_00180	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HDGNIKPO_00181	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDGNIKPO_00182	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDGNIKPO_00183	9.92e-212	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HDGNIKPO_00184	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HDGNIKPO_00185	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDGNIKPO_00186	5.99e-213	mleR	-	-	K	-	-	-	LysR substrate binding domain
HDGNIKPO_00187	8.71e-35	-	-	-	M	-	-	-	domain protein
HDGNIKPO_00188	0.0	-	-	-	M	-	-	-	domain protein
HDGNIKPO_00190	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HDGNIKPO_00191	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDGNIKPO_00192	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDGNIKPO_00193	1.31e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDGNIKPO_00194	1.19e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDGNIKPO_00195	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDGNIKPO_00196	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HDGNIKPO_00197	1.01e-228	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HDGNIKPO_00198	6.33e-46	-	-	-	-	-	-	-	-
HDGNIKPO_00199	4.69e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HDGNIKPO_00200	6.21e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HDGNIKPO_00201	2.6e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDGNIKPO_00202	3.81e-18	-	-	-	-	-	-	-	-
HDGNIKPO_00203	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDGNIKPO_00204	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDGNIKPO_00205	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HDGNIKPO_00206	6.11e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HDGNIKPO_00207	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDGNIKPO_00208	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HDGNIKPO_00209	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HDGNIKPO_00210	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HDGNIKPO_00211	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDGNIKPO_00212	1.2e-91	-	-	-	-	-	-	-	-
HDGNIKPO_00213	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDGNIKPO_00215	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDGNIKPO_00216	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDGNIKPO_00217	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HDGNIKPO_00218	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_00219	2.61e-282	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HDGNIKPO_00220	1.21e-111	-	-	-	-	-	-	-	-
HDGNIKPO_00221	1.96e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDGNIKPO_00222	7.19e-68	-	-	-	-	-	-	-	-
HDGNIKPO_00223	1.22e-125	-	-	-	-	-	-	-	-
HDGNIKPO_00224	2.98e-90	-	-	-	-	-	-	-	-
HDGNIKPO_00225	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HDGNIKPO_00226	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HDGNIKPO_00227	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HDGNIKPO_00228	1.89e-159	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HDGNIKPO_00229	4.08e-291	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_00230	6.14e-53	-	-	-	-	-	-	-	-
HDGNIKPO_00231	7.59e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HDGNIKPO_00232	3.63e-271	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HDGNIKPO_00233	5.06e-259	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HDGNIKPO_00234	1.22e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HDGNIKPO_00235	2.02e-245	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HDGNIKPO_00236	3.68e-125	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HDGNIKPO_00237	5.78e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HDGNIKPO_00238	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HDGNIKPO_00239	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HDGNIKPO_00240	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HDGNIKPO_00241	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HDGNIKPO_00242	2.21e-56	-	-	-	-	-	-	-	-
HDGNIKPO_00243	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HDGNIKPO_00244	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDGNIKPO_00245	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDGNIKPO_00246	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDGNIKPO_00247	2.6e-185	-	-	-	-	-	-	-	-
HDGNIKPO_00248	6.2e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDGNIKPO_00249	7.84e-92	-	-	-	-	-	-	-	-
HDGNIKPO_00250	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_00251	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_00252	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDGNIKPO_00253	2.6e-149	-	-	-	-	-	-	-	-
HDGNIKPO_00254	2.81e-55	-	-	-	-	-	-	-	-
HDGNIKPO_00255	1.55e-55	-	-	-	-	-	-	-	-
HDGNIKPO_00256	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_00257	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDGNIKPO_00258	1.4e-314	hpk2	-	-	T	-	-	-	Histidine kinase
HDGNIKPO_00259	3.28e-166	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HDGNIKPO_00260	9.86e-65	-	-	-	-	-	-	-	-
HDGNIKPO_00261	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDGNIKPO_00262	3.96e-310	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_00263	3.35e-75	-	-	-	-	-	-	-	-
HDGNIKPO_00264	2.87e-56	-	-	-	-	-	-	-	-
HDGNIKPO_00265	1.76e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDGNIKPO_00266	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HDGNIKPO_00267	1.49e-63	-	-	-	-	-	-	-	-
HDGNIKPO_00268	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HDGNIKPO_00269	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HDGNIKPO_00270	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HDGNIKPO_00271	8.31e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HDGNIKPO_00272	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HDGNIKPO_00273	2.38e-291	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HDGNIKPO_00274	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_00275	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_00276	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_00277	9.9e-75	-	-	-	M	-	-	-	Lysin motif
HDGNIKPO_00278	1.43e-82	-	-	-	M	-	-	-	LysM domain protein
HDGNIKPO_00279	8.48e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HDGNIKPO_00280	7.42e-228	-	-	-	-	-	-	-	-
HDGNIKPO_00281	6.88e-170	-	-	-	-	-	-	-	-
HDGNIKPO_00282	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HDGNIKPO_00283	2.03e-75	-	-	-	-	-	-	-	-
HDGNIKPO_00284	5.31e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDGNIKPO_00285	1.08e-101	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HDGNIKPO_00286	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_00287	4.76e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDGNIKPO_00289	1.04e-35	-	-	-	-	-	-	-	-
HDGNIKPO_00290	9.25e-32	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
HDGNIKPO_00291	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_00292	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_00293	9e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_00294	1.46e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDGNIKPO_00295	1.5e-124	-	-	-	K	-	-	-	Cupin domain
HDGNIKPO_00296	8.08e-110	-	-	-	S	-	-	-	ASCH
HDGNIKPO_00297	1.88e-111	-	-	-	K	-	-	-	GNAT family
HDGNIKPO_00298	2.05e-115	-	-	-	K	-	-	-	acetyltransferase
HDGNIKPO_00299	2.06e-30	-	-	-	-	-	-	-	-
HDGNIKPO_00300	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDGNIKPO_00301	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_00302	3.6e-242	-	-	-	-	-	-	-	-
HDGNIKPO_00303	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HDGNIKPO_00304	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HDGNIKPO_00305	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_00307	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HDGNIKPO_00308	2.03e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HDGNIKPO_00309	2.97e-41	-	-	-	-	-	-	-	-
HDGNIKPO_00310	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDGNIKPO_00311	6.4e-54	-	-	-	-	-	-	-	-
HDGNIKPO_00312	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HDGNIKPO_00313	7.1e-226	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDGNIKPO_00314	6.71e-80	-	-	-	S	-	-	-	CHY zinc finger
HDGNIKPO_00315	2.21e-284	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDGNIKPO_00316	1.1e-280	-	-	-	-	-	-	-	-
HDGNIKPO_00317	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HDGNIKPO_00318	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDGNIKPO_00319	2.76e-59	-	-	-	-	-	-	-	-
HDGNIKPO_00320	2.39e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HDGNIKPO_00321	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HDGNIKPO_00322	1.05e-308	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HDGNIKPO_00323	3.82e-228	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDGNIKPO_00324	8.95e-60	-	-	-	-	-	-	-	-
HDGNIKPO_00325	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HDGNIKPO_00326	6.87e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HDGNIKPO_00327	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HDGNIKPO_00328	1.08e-71	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HDGNIKPO_00329	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HDGNIKPO_00330	3.25e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HDGNIKPO_00331	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HDGNIKPO_00332	2.16e-103	-	-	-	-	-	-	-	-
HDGNIKPO_00333	4.9e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDGNIKPO_00334	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HDGNIKPO_00335	1.03e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDGNIKPO_00336	2.39e-73	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HDGNIKPO_00337	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDGNIKPO_00338	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_00339	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDGNIKPO_00340	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDGNIKPO_00341	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HDGNIKPO_00342	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDGNIKPO_00343	0.0	-	-	-	M	-	-	-	domain protein
HDGNIKPO_00344	4e-78	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HDGNIKPO_00345	7.12e-226	-	-	-	-	-	-	-	-
HDGNIKPO_00346	6.97e-45	-	-	-	-	-	-	-	-
HDGNIKPO_00347	2.35e-52	-	-	-	-	-	-	-	-
HDGNIKPO_00348	2.59e-84	-	-	-	-	-	-	-	-
HDGNIKPO_00349	4.92e-90	-	-	-	S	-	-	-	Immunity protein 63
HDGNIKPO_00350	1.51e-17	-	-	-	L	-	-	-	LXG domain of WXG superfamily
HDGNIKPO_00351	5.32e-51	-	-	-	-	-	-	-	-
HDGNIKPO_00352	9.2e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDGNIKPO_00353	7.81e-263	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HDGNIKPO_00354	1.61e-184	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HDGNIKPO_00355	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_00356	8.38e-192	-	-	-	S	-	-	-	hydrolase
HDGNIKPO_00357	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDGNIKPO_00358	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDGNIKPO_00360	1.15e-43	-	-	-	-	-	-	-	-
HDGNIKPO_00361	6.24e-25	plnR	-	-	-	-	-	-	-
HDGNIKPO_00362	9.76e-153	-	-	-	-	-	-	-	-
HDGNIKPO_00363	3.29e-32	plnK	-	-	-	-	-	-	-
HDGNIKPO_00364	8.53e-34	plnJ	-	-	-	-	-	-	-
HDGNIKPO_00365	4.08e-39	-	-	-	-	-	-	-	-
HDGNIKPO_00367	5.58e-291	-	-	-	M	-	-	-	Glycosyl transferase family 2
HDGNIKPO_00368	2.08e-160	plnP	-	-	S	-	-	-	CAAX protease self-immunity
HDGNIKPO_00369	1.22e-36	-	-	-	-	-	-	-	-
HDGNIKPO_00370	1.9e-25	plnA	-	-	-	-	-	-	-
HDGNIKPO_00371	2.08e-301	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDGNIKPO_00372	2.48e-172	sppR	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDGNIKPO_00373	1.05e-173	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDGNIKPO_00374	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_00375	1.93e-31	plnF	-	-	-	-	-	-	-
HDGNIKPO_00376	8.82e-32	-	-	-	-	-	-	-	-
HDGNIKPO_00377	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDGNIKPO_00378	1.49e-309	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HDGNIKPO_00379	3.26e-124	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_00380	5.04e-155	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_00381	2.75e-145	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_00382	3.34e-147	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_00383	1.85e-40	-	-	-	-	-	-	-	-
HDGNIKPO_00384	0.0	-	-	-	L	-	-	-	DNA helicase
HDGNIKPO_00385	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HDGNIKPO_00386	8.19e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDGNIKPO_00387	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HDGNIKPO_00388	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_00389	9.68e-34	-	-	-	-	-	-	-	-
HDGNIKPO_00390	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HDGNIKPO_00391	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_00392	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_00393	6.97e-209	-	-	-	GK	-	-	-	ROK family
HDGNIKPO_00394	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDGNIKPO_00395	2.94e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDGNIKPO_00396	1.23e-262	-	-	-	-	-	-	-	-
HDGNIKPO_00397	5.08e-194	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDGNIKPO_00398	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDGNIKPO_00399	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HDGNIKPO_00400	4.65e-229	-	-	-	-	-	-	-	-
HDGNIKPO_00401	8.73e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HDGNIKPO_00402	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HDGNIKPO_00403	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HDGNIKPO_00404	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDGNIKPO_00405	4.08e-270	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HDGNIKPO_00406	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HDGNIKPO_00407	3.1e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDGNIKPO_00408	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDGNIKPO_00409	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HDGNIKPO_00410	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDGNIKPO_00411	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HDGNIKPO_00412	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDGNIKPO_00413	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HDGNIKPO_00414	2.4e-56	-	-	-	S	-	-	-	ankyrin repeats
HDGNIKPO_00415	5.3e-49	-	-	-	-	-	-	-	-
HDGNIKPO_00416	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HDGNIKPO_00417	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDGNIKPO_00418	1.1e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HDGNIKPO_00419	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDGNIKPO_00420	1.15e-235	-	-	-	S	-	-	-	DUF218 domain
HDGNIKPO_00421	4.31e-179	-	-	-	-	-	-	-	-
HDGNIKPO_00422	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
HDGNIKPO_00423	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HDGNIKPO_00424	8.97e-200	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HDGNIKPO_00425	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HDGNIKPO_00426	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDGNIKPO_00427	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDGNIKPO_00428	2.66e-308	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDGNIKPO_00429	1.32e-289	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HDGNIKPO_00430	1.52e-158	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HDGNIKPO_00431	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HDGNIKPO_00432	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HDGNIKPO_00433	4.01e-36	-	-	-	-	-	-	-	-
HDGNIKPO_00434	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDGNIKPO_00435	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HDGNIKPO_00436	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HDGNIKPO_00437	1.05e-273	-	-	-	J	-	-	-	translation release factor activity
HDGNIKPO_00438	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HDGNIKPO_00439	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HDGNIKPO_00440	4.58e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HDGNIKPO_00441	3.71e-189	-	-	-	-	-	-	-	-
HDGNIKPO_00442	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDGNIKPO_00443	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDGNIKPO_00444	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDGNIKPO_00445	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDGNIKPO_00446	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HDGNIKPO_00447	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDGNIKPO_00448	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HDGNIKPO_00449	1.06e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDGNIKPO_00450	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HDGNIKPO_00451	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDGNIKPO_00452	3.7e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDGNIKPO_00453	6.25e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDGNIKPO_00454	1.38e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDGNIKPO_00455	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HDGNIKPO_00456	2.21e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HDGNIKPO_00457	2.16e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDGNIKPO_00458	5.3e-110	queT	-	-	S	-	-	-	QueT transporter
HDGNIKPO_00459	5.29e-211	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HDGNIKPO_00460	8.1e-157	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HDGNIKPO_00461	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HDGNIKPO_00462	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HDGNIKPO_00463	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HDGNIKPO_00464	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDGNIKPO_00465	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDGNIKPO_00466	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HDGNIKPO_00467	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HDGNIKPO_00469	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HDGNIKPO_00470	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HDGNIKPO_00471	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDGNIKPO_00472	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HDGNIKPO_00473	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDGNIKPO_00474	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDGNIKPO_00475	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDGNIKPO_00476	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HDGNIKPO_00479	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HDGNIKPO_00482	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HDGNIKPO_00483	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDGNIKPO_00487	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HDGNIKPO_00488	2.78e-71	-	-	-	S	-	-	-	Cupin domain
HDGNIKPO_00489	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HDGNIKPO_00490	6.2e-245	ysdE	-	-	P	-	-	-	Citrate transporter
HDGNIKPO_00491	5.06e-194	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HDGNIKPO_00492	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDGNIKPO_00493	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDGNIKPO_00494	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HDGNIKPO_00495	6.62e-176	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDGNIKPO_00496	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDGNIKPO_00497	1.51e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDGNIKPO_00498	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HDGNIKPO_00499	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HDGNIKPO_00500	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HDGNIKPO_00501	6.25e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HDGNIKPO_00502	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HDGNIKPO_00503	2.93e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDGNIKPO_00506	4.34e-31	-	-	-	-	-	-	-	-
HDGNIKPO_00507	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HDGNIKPO_00510	3.4e-206	-	-	-	G	-	-	-	Peptidase_C39 like family
HDGNIKPO_00511	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDGNIKPO_00512	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HDGNIKPO_00513	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HDGNIKPO_00514	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HDGNIKPO_00515	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HDGNIKPO_00516	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HDGNIKPO_00517	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDGNIKPO_00518	2.58e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDGNIKPO_00519	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HDGNIKPO_00520	1.98e-314	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HDGNIKPO_00521	6.33e-185	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDGNIKPO_00522	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HDGNIKPO_00523	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDGNIKPO_00524	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HDGNIKPO_00525	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HDGNIKPO_00526	3.3e-166	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDGNIKPO_00527	4.57e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HDGNIKPO_00528	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HDGNIKPO_00529	4.65e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDGNIKPO_00530	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HDGNIKPO_00531	3.29e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HDGNIKPO_00532	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDGNIKPO_00533	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HDGNIKPO_00534	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDGNIKPO_00535	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HDGNIKPO_00536	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDGNIKPO_00537	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDGNIKPO_00538	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HDGNIKPO_00539	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HDGNIKPO_00540	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDGNIKPO_00541	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDGNIKPO_00542	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HDGNIKPO_00543	6.91e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDGNIKPO_00544	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDGNIKPO_00545	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDGNIKPO_00546	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDGNIKPO_00547	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDGNIKPO_00548	5.84e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HDGNIKPO_00549	4.16e-87	-	-	-	L	-	-	-	nuclease
HDGNIKPO_00550	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDGNIKPO_00551	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HDGNIKPO_00552	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDGNIKPO_00553	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDGNIKPO_00554	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HDGNIKPO_00555	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HDGNIKPO_00556	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDGNIKPO_00557	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDGNIKPO_00558	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDGNIKPO_00559	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDGNIKPO_00560	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HDGNIKPO_00561	2.22e-153	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDGNIKPO_00562	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HDGNIKPO_00563	9.5e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HDGNIKPO_00564	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HDGNIKPO_00565	1.53e-212	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDGNIKPO_00566	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HDGNIKPO_00567	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDGNIKPO_00568	8.87e-269	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HDGNIKPO_00569	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HDGNIKPO_00570	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_00571	2.65e-177	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HDGNIKPO_00572	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HDGNIKPO_00573	4.7e-240	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HDGNIKPO_00574	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HDGNIKPO_00575	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HDGNIKPO_00576	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDGNIKPO_00577	7.63e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDGNIKPO_00578	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HDGNIKPO_00579	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDGNIKPO_00580	1.68e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_00581	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDGNIKPO_00582	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDGNIKPO_00583	0.0	ydaO	-	-	E	-	-	-	amino acid
HDGNIKPO_00584	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HDGNIKPO_00585	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HDGNIKPO_00586	9.07e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HDGNIKPO_00587	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HDGNIKPO_00588	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HDGNIKPO_00589	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDGNIKPO_00590	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDGNIKPO_00591	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDGNIKPO_00592	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HDGNIKPO_00593	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HDGNIKPO_00594	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDGNIKPO_00595	9.81e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HDGNIKPO_00596	2.22e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HDGNIKPO_00597	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HDGNIKPO_00598	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDGNIKPO_00599	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDGNIKPO_00600	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HDGNIKPO_00601	7.97e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HDGNIKPO_00602	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HDGNIKPO_00603	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDGNIKPO_00604	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDGNIKPO_00605	2.82e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HDGNIKPO_00606	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HDGNIKPO_00607	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDGNIKPO_00608	0.0	nox	-	-	C	-	-	-	NADH oxidase
HDGNIKPO_00609	2.6e-206	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HDGNIKPO_00610	4.95e-310	-	-	-	-	-	-	-	-
HDGNIKPO_00611	2.39e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
HDGNIKPO_00612	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HDGNIKPO_00613	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HDGNIKPO_00614	7.91e-172	-	-	-	T	-	-	-	diguanylate cyclase activity
HDGNIKPO_00615	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDGNIKPO_00616	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HDGNIKPO_00617	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HDGNIKPO_00618	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDGNIKPO_00619	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDGNIKPO_00620	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDGNIKPO_00621	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HDGNIKPO_00622	2.53e-266	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HDGNIKPO_00623	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HDGNIKPO_00624	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDGNIKPO_00625	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDGNIKPO_00626	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDGNIKPO_00627	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDGNIKPO_00628	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HDGNIKPO_00629	8.62e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HDGNIKPO_00630	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HDGNIKPO_00631	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HDGNIKPO_00632	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HDGNIKPO_00633	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDGNIKPO_00634	1.55e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDGNIKPO_00635	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDGNIKPO_00637	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HDGNIKPO_00638	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HDGNIKPO_00639	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDGNIKPO_00640	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HDGNIKPO_00641	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDGNIKPO_00642	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDGNIKPO_00643	6.94e-169	-	-	-	-	-	-	-	-
HDGNIKPO_00644	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HDGNIKPO_00645	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HDGNIKPO_00646	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HDGNIKPO_00647	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDGNIKPO_00648	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDGNIKPO_00649	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDGNIKPO_00650	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_00651	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_00652	5.62e-137	-	-	-	-	-	-	-	-
HDGNIKPO_00653	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDGNIKPO_00654	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDGNIKPO_00655	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HDGNIKPO_00656	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HDGNIKPO_00657	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDGNIKPO_00658	7.18e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HDGNIKPO_00659	5.96e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HDGNIKPO_00660	2.72e-207	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HDGNIKPO_00661	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HDGNIKPO_00662	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDGNIKPO_00663	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDGNIKPO_00664	6.9e-157	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HDGNIKPO_00665	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDGNIKPO_00666	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HDGNIKPO_00667	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDGNIKPO_00668	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDGNIKPO_00669	5.44e-159	-	-	-	T	-	-	-	EAL domain
HDGNIKPO_00670	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HDGNIKPO_00671	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_00672	2.07e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDGNIKPO_00673	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_00674	1.96e-69	-	-	-	-	-	-	-	-
HDGNIKPO_00675	2.49e-95	-	-	-	-	-	-	-	-
HDGNIKPO_00676	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HDGNIKPO_00677	3.51e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HDGNIKPO_00678	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDGNIKPO_00679	5.03e-183	-	-	-	-	-	-	-	-
HDGNIKPO_00681	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HDGNIKPO_00682	3.88e-46	-	-	-	-	-	-	-	-
HDGNIKPO_00683	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HDGNIKPO_00684	4.22e-228	-	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_00685	1.67e-35	-	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_00686	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDGNIKPO_00687	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HDGNIKPO_00688	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HDGNIKPO_00689	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HDGNIKPO_00690	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_00691	1.36e-27	-	-	-	-	-	-	-	-
HDGNIKPO_00692	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HDGNIKPO_00693	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDGNIKPO_00694	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HDGNIKPO_00695	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDGNIKPO_00696	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HDGNIKPO_00697	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDGNIKPO_00698	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HDGNIKPO_00699	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDGNIKPO_00700	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HDGNIKPO_00701	1.09e-60	-	-	-	-	-	-	-	-
HDGNIKPO_00702	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDGNIKPO_00703	6.12e-115	-	-	-	-	-	-	-	-
HDGNIKPO_00704	5.24e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HDGNIKPO_00705	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HDGNIKPO_00706	1.48e-27	-	-	-	-	-	-	-	-
HDGNIKPO_00707	6.02e-135	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HDGNIKPO_00708	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HDGNIKPO_00709	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HDGNIKPO_00710	1.01e-188	-	-	-	-	-	-	-	-
HDGNIKPO_00711	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HDGNIKPO_00712	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDGNIKPO_00713	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDGNIKPO_00714	1.23e-52	-	-	-	-	-	-	-	-
HDGNIKPO_00716	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_00717	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HDGNIKPO_00718	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_00719	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_00720	2.1e-109	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDGNIKPO_00721	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDGNIKPO_00722	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDGNIKPO_00723	6.38e-182	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HDGNIKPO_00724	7.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HDGNIKPO_00725	2.55e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDGNIKPO_00726	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HDGNIKPO_00727	3.08e-93	-	-	-	K	-	-	-	MarR family
HDGNIKPO_00728	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDGNIKPO_00729	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDGNIKPO_00730	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_00731	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDGNIKPO_00732	1.13e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HDGNIKPO_00733	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HDGNIKPO_00734	1.61e-36	-	-	-	-	-	-	-	-
HDGNIKPO_00735	2.61e-163	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HDGNIKPO_00736	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HDGNIKPO_00737	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HDGNIKPO_00738	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HDGNIKPO_00739	1.07e-203	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDGNIKPO_00740	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDGNIKPO_00741	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_00742	1.75e-142	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HDGNIKPO_00743	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HDGNIKPO_00744	3.59e-212	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HDGNIKPO_00745	3.69e-230	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HDGNIKPO_00746	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HDGNIKPO_00747	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HDGNIKPO_00748	1.89e-114	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDGNIKPO_00750	1.1e-123	-	-	-	S	-	-	-	KilA-N domain
HDGNIKPO_00752	4.78e-27	-	-	-	S	-	-	-	Short C-terminal domain
HDGNIKPO_00756	5.44e-12	-	-	-	K	-	-	-	transcriptional
HDGNIKPO_00757	1.13e-242	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_00758	3.57e-129	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HDGNIKPO_00759	1.08e-71	-	-	-	-	-	-	-	-
HDGNIKPO_00760	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HDGNIKPO_00761	0.0	-	-	-	L	-	-	-	AAA domain
HDGNIKPO_00762	2.01e-149	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_00763	1.53e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDGNIKPO_00764	4.73e-302	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HDGNIKPO_00765	2.66e-301	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HDGNIKPO_00766	1.59e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDGNIKPO_00767	6.44e-121	-	-	-	D	-	-	-	nuclear chromosome segregation
HDGNIKPO_00768	6.46e-111	-	-	-	-	-	-	-	-
HDGNIKPO_00769	5.53e-205	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HDGNIKPO_00770	6.35e-69	-	-	-	-	-	-	-	-
HDGNIKPO_00771	3.61e-61	-	-	-	S	-	-	-	MORN repeat
HDGNIKPO_00772	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HDGNIKPO_00773	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HDGNIKPO_00774	1.95e-116	-	-	-	-	-	-	-	-
HDGNIKPO_00775	5.74e-32	-	-	-	-	-	-	-	-
HDGNIKPO_00776	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDGNIKPO_00777	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDGNIKPO_00778	2.02e-192	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HDGNIKPO_00779	2.11e-211	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HDGNIKPO_00780	4.46e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HDGNIKPO_00781	2.19e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
HDGNIKPO_00782	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HDGNIKPO_00783	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HDGNIKPO_00784	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HDGNIKPO_00785	1.97e-73	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HDGNIKPO_00786	6.29e-220	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDGNIKPO_00787	3.62e-32	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HDGNIKPO_00788	8.97e-63	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
HDGNIKPO_00789	2.31e-117	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HDGNIKPO_00790	0.0	-	-	-	M	-	-	-	MucBP domain
HDGNIKPO_00791	1.42e-08	-	-	-	-	-	-	-	-
HDGNIKPO_00792	1.27e-115	-	-	-	S	-	-	-	AAA domain
HDGNIKPO_00793	1.83e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
HDGNIKPO_00794	1.09e-123	-	-	-	K	-	-	-	Helix-turn-helix domain
HDGNIKPO_00795	1.6e-219	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_00796	0.0	-	-	-	C	-	-	-	FMN_bind
HDGNIKPO_00798	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_00799	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDGNIKPO_00800	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HDGNIKPO_00801	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HDGNIKPO_00802	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDGNIKPO_00803	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HDGNIKPO_00804	9.05e-55	-	-	-	-	-	-	-	-
HDGNIKPO_00805	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HDGNIKPO_00806	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HDGNIKPO_00807	1.65e-209	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDGNIKPO_00808	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDGNIKPO_00809	8.34e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDGNIKPO_00810	3.91e-244	-	-	-	-	-	-	-	-
HDGNIKPO_00811	2.41e-280	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HDGNIKPO_00812	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HDGNIKPO_00813	1.22e-132	-	-	-	K	-	-	-	FR47-like protein
HDGNIKPO_00814	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HDGNIKPO_00815	3.33e-64	-	-	-	-	-	-	-	-
HDGNIKPO_00816	3.48e-245	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDGNIKPO_00817	0.0	xylP2	-	-	G	-	-	-	symporter
HDGNIKPO_00818	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDGNIKPO_00819	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HDGNIKPO_00820	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HDGNIKPO_00821	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HDGNIKPO_00822	1.43e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HDGNIKPO_00823	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HDGNIKPO_00824	1.46e-170	-	-	-	-	-	-	-	-
HDGNIKPO_00825	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HDGNIKPO_00826	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HDGNIKPO_00827	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HDGNIKPO_00828	1.36e-77	-	-	-	-	-	-	-	-
HDGNIKPO_00829	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HDGNIKPO_00830	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HDGNIKPO_00831	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDGNIKPO_00832	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HDGNIKPO_00833	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HDGNIKPO_00834	2.05e-153	-	-	-	I	-	-	-	phosphatase
HDGNIKPO_00835	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDGNIKPO_00836	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDGNIKPO_00837	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_00838	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HDGNIKPO_00839	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HDGNIKPO_00840	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HDGNIKPO_00841	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HDGNIKPO_00842	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDGNIKPO_00850	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HDGNIKPO_00851	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDGNIKPO_00852	6.72e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_00853	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDGNIKPO_00854	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDGNIKPO_00855	8.58e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HDGNIKPO_00856	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDGNIKPO_00857	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDGNIKPO_00858	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDGNIKPO_00859	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HDGNIKPO_00860	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDGNIKPO_00861	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HDGNIKPO_00862	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDGNIKPO_00863	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDGNIKPO_00864	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDGNIKPO_00865	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDGNIKPO_00866	3.16e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDGNIKPO_00867	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDGNIKPO_00868	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HDGNIKPO_00869	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDGNIKPO_00870	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDGNIKPO_00871	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDGNIKPO_00872	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDGNIKPO_00873	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDGNIKPO_00874	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDGNIKPO_00875	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDGNIKPO_00876	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDGNIKPO_00877	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HDGNIKPO_00878	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HDGNIKPO_00879	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDGNIKPO_00880	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDGNIKPO_00881	1.19e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDGNIKPO_00882	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDGNIKPO_00883	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDGNIKPO_00884	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDGNIKPO_00885	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HDGNIKPO_00886	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDGNIKPO_00887	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HDGNIKPO_00888	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HDGNIKPO_00889	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HDGNIKPO_00890	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HDGNIKPO_00891	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDGNIKPO_00892	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDGNIKPO_00893	2.85e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDGNIKPO_00894	9.72e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDGNIKPO_00895	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDGNIKPO_00896	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDGNIKPO_00897	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HDGNIKPO_00898	2.44e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HDGNIKPO_00899	1e-234	-	-	-	S	-	-	-	Membrane
HDGNIKPO_00900	2.61e-259	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HDGNIKPO_00901	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDGNIKPO_00902	5.53e-210	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDGNIKPO_00903	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HDGNIKPO_00904	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDGNIKPO_00906	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDGNIKPO_00907	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HDGNIKPO_00908	2.01e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HDGNIKPO_00909	3.01e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HDGNIKPO_00910	6.33e-254	-	-	-	K	-	-	-	Helix-turn-helix domain
HDGNIKPO_00911	9.07e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HDGNIKPO_00912	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDGNIKPO_00913	1.44e-179	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HDGNIKPO_00914	3e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDGNIKPO_00915	1.18e-66	-	-	-	-	-	-	-	-
HDGNIKPO_00916	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HDGNIKPO_00917	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HDGNIKPO_00918	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HDGNIKPO_00919	5.51e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HDGNIKPO_00920	2.52e-240	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HDGNIKPO_00921	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HDGNIKPO_00922	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HDGNIKPO_00923	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HDGNIKPO_00925	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDGNIKPO_00926	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDGNIKPO_00927	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HDGNIKPO_00928	4.35e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HDGNIKPO_00929	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_00930	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HDGNIKPO_00931	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HDGNIKPO_00932	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HDGNIKPO_00933	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDGNIKPO_00934	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HDGNIKPO_00935	2.56e-34	-	-	-	-	-	-	-	-
HDGNIKPO_00936	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HDGNIKPO_00937	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HDGNIKPO_00938	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HDGNIKPO_00939	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HDGNIKPO_00940	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HDGNIKPO_00941	7.68e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HDGNIKPO_00942	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDGNIKPO_00943	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HDGNIKPO_00944	9.47e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDGNIKPO_00945	5.66e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HDGNIKPO_00946	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDGNIKPO_00947	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HDGNIKPO_00948	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDGNIKPO_00949	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HDGNIKPO_00950	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDGNIKPO_00951	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HDGNIKPO_00952	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDGNIKPO_00953	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDGNIKPO_00954	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDGNIKPO_00955	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HDGNIKPO_00956	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDGNIKPO_00957	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_00958	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HDGNIKPO_00959	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_00960	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDGNIKPO_00961	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HDGNIKPO_00962	1.1e-185	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HDGNIKPO_00963	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HDGNIKPO_00964	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HDGNIKPO_00965	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HDGNIKPO_00966	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HDGNIKPO_00968	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HDGNIKPO_00969	1.56e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_00970	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDGNIKPO_00972	7.62e-97	-	-	-	-	-	-	-	-
HDGNIKPO_00973	2.9e-139	-	-	-	-	-	-	-	-
HDGNIKPO_00974	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HDGNIKPO_00975	1.15e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HDGNIKPO_00976	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDGNIKPO_00977	1.01e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HDGNIKPO_00978	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDGNIKPO_00979	6.08e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HDGNIKPO_00981	2.23e-10	cap5B	-	-	D	-	-	-	NUBPL iron-transfer P-loop NTPase
HDGNIKPO_00982	7.12e-09	-	-	-	V	-	-	-	Beta-lactamase
HDGNIKPO_00983	1.43e-28	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HDGNIKPO_00984	9.47e-99	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HDGNIKPO_00985	2.84e-117	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HDGNIKPO_00986	1.4e-62	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDGNIKPO_00987	6.89e-68	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HDGNIKPO_00988	2.02e-214	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HDGNIKPO_00989	1.33e-82	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HDGNIKPO_00990	2.89e-129	-	-	-	M	-	-	-	Parallel beta-helix repeats
HDGNIKPO_00991	8.79e-239	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDGNIKPO_00992	3.69e-130	-	-	-	L	-	-	-	Integrase
HDGNIKPO_00993	2.18e-168	epsB	-	-	M	-	-	-	biosynthesis protein
HDGNIKPO_00994	1.95e-162	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HDGNIKPO_00995	1.69e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HDGNIKPO_00996	1.33e-226	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HDGNIKPO_00997	8.38e-160	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HDGNIKPO_00998	1.47e-166	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HDGNIKPO_00999	1.54e-159	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HDGNIKPO_01000	2.08e-218	-	-	-	-	-	-	-	-
HDGNIKPO_01001	2.08e-167	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HDGNIKPO_01002	5.71e-57	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HDGNIKPO_01003	2.34e-105	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HDGNIKPO_01004	1e-28	cps2K	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
HDGNIKPO_01005	1.09e-138	-	-	-	M	-	-	-	domain protein
HDGNIKPO_01006	3.59e-39	-	-	-	M	-	-	-	domain protein
HDGNIKPO_01007	2.5e-173	-	-	-	M	ko:K21493	-	ko00000,ko01000,ko02048	self proteolysis
HDGNIKPO_01008	3.23e-58	-	-	-	-	-	-	-	-
HDGNIKPO_01010	7.45e-152	-	-	-	-	-	-	-	-
HDGNIKPO_01011	3.07e-48	-	-	-	-	-	-	-	-
HDGNIKPO_01012	9.17e-41	-	-	-	-	-	-	-	-
HDGNIKPO_01013	2.67e-173	-	-	-	-	-	-	-	-
HDGNIKPO_01014	9.94e-142	-	-	-	-	-	-	-	-
HDGNIKPO_01015	0.000143	-	-	-	U	ko:K15125	ko05133,map05133	ko00000,ko00001,ko00536	Large exoproteins involved in heme utilization or adhesion
HDGNIKPO_01016	4.75e-191	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HDGNIKPO_01018	2.32e-152	-	-	-	-	-	-	-	-
HDGNIKPO_01020	8.72e-73	-	-	-	S	-	-	-	Immunity protein 63
HDGNIKPO_01021	7.72e-35	-	-	-	S	-	-	-	Barstar (barnase inhibitor)
HDGNIKPO_01022	1.54e-219	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HDGNIKPO_01023	3.01e-225	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HDGNIKPO_01024	2.81e-282	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HDGNIKPO_01025	1.6e-259	cps3D	-	-	-	-	-	-	-
HDGNIKPO_01026	2.92e-145	cps3E	-	-	-	-	-	-	-
HDGNIKPO_01027	1.73e-207	cps3F	-	-	-	-	-	-	-
HDGNIKPO_01028	4.2e-264	cps3H	-	-	-	-	-	-	-
HDGNIKPO_01029	5.06e-260	cps3I	-	-	G	-	-	-	Acyltransferase family
HDGNIKPO_01030	8.42e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HDGNIKPO_01031	2.91e-176	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDGNIKPO_01032	0.0	-	-	-	M	-	-	-	domain protein
HDGNIKPO_01033	5.36e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDGNIKPO_01034	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HDGNIKPO_01035	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HDGNIKPO_01036	9.02e-70	-	-	-	-	-	-	-	-
HDGNIKPO_01037	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HDGNIKPO_01038	1.95e-41	-	-	-	-	-	-	-	-
HDGNIKPO_01039	1.35e-34	-	-	-	-	-	-	-	-
HDGNIKPO_01040	6.87e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HDGNIKPO_01041	7.74e-168	-	-	-	-	-	-	-	-
HDGNIKPO_01042	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HDGNIKPO_01043	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HDGNIKPO_01044	1.37e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
HDGNIKPO_01045	5.64e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HDGNIKPO_01046	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HDGNIKPO_01047	4.02e-166	pbpX	-	-	V	-	-	-	Beta-lactamase
HDGNIKPO_01048	4.22e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDGNIKPO_01049	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HDGNIKPO_01050	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HDGNIKPO_01051	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HDGNIKPO_01052	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HDGNIKPO_01053	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HDGNIKPO_01054	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDGNIKPO_01055	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDGNIKPO_01056	0.0	-	-	-	-	-	-	-	-
HDGNIKPO_01057	1.49e-252	-	-	-	M	-	-	-	MucBP domain
HDGNIKPO_01058	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HDGNIKPO_01059	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDGNIKPO_01060	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HDGNIKPO_01061	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDGNIKPO_01062	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDGNIKPO_01063	2.42e-239	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDGNIKPO_01064	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDGNIKPO_01065	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDGNIKPO_01066	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDGNIKPO_01067	2.5e-132	-	-	-	L	-	-	-	Integrase
HDGNIKPO_01068	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HDGNIKPO_01069	5.6e-41	-	-	-	-	-	-	-	-
HDGNIKPO_01070	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HDGNIKPO_01071	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDGNIKPO_01072	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HDGNIKPO_01073	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HDGNIKPO_01074	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDGNIKPO_01075	2.29e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDGNIKPO_01076	1.22e-292	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDGNIKPO_01077	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HDGNIKPO_01078	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDGNIKPO_01081	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HDGNIKPO_01093	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HDGNIKPO_01094	1.28e-236	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HDGNIKPO_01095	1.25e-124	-	-	-	-	-	-	-	-
HDGNIKPO_01096	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDGNIKPO_01097	1.46e-200	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HDGNIKPO_01098	5.39e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDGNIKPO_01099	2.95e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HDGNIKPO_01100	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HDGNIKPO_01101	6.48e-215	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HDGNIKPO_01102	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDGNIKPO_01103	5.79e-158	-	-	-	-	-	-	-	-
HDGNIKPO_01104	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDGNIKPO_01105	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_01106	1.92e-304	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HDGNIKPO_01107	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HDGNIKPO_01108	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDGNIKPO_01109	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDGNIKPO_01110	2.68e-39	-	-	-	-	-	-	-	-
HDGNIKPO_01111	7.15e-121	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HDGNIKPO_01112	2.07e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HDGNIKPO_01113	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HDGNIKPO_01114	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HDGNIKPO_01115	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDGNIKPO_01116	5.24e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDGNIKPO_01117	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HDGNIKPO_01118	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDGNIKPO_01119	1.02e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HDGNIKPO_01120	2.27e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDGNIKPO_01121	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_01122	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDGNIKPO_01123	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HDGNIKPO_01124	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HDGNIKPO_01125	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDGNIKPO_01126	0.0	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HDGNIKPO_01128	3.63e-164	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HDGNIKPO_01129	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_01130	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HDGNIKPO_01131	4.03e-197	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDGNIKPO_01132	1.01e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDGNIKPO_01133	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HDGNIKPO_01134	6.59e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDGNIKPO_01135	1.97e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDGNIKPO_01136	7.83e-140	-	-	-	-	-	-	-	-
HDGNIKPO_01137	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDGNIKPO_01138	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDGNIKPO_01139	5.37e-74	-	-	-	-	-	-	-	-
HDGNIKPO_01140	4.56e-78	-	-	-	-	-	-	-	-
HDGNIKPO_01141	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_01142	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HDGNIKPO_01143	2.95e-117	-	-	-	-	-	-	-	-
HDGNIKPO_01144	7.12e-62	-	-	-	-	-	-	-	-
HDGNIKPO_01145	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HDGNIKPO_01147	2.25e-120	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDGNIKPO_01148	5.8e-172	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
HDGNIKPO_01149	1.15e-99	-	-	-	S	-	-	-	AAA ATPase domain
HDGNIKPO_01152	1.98e-23	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDGNIKPO_01153	5.72e-27	-	-	-	-	-	-	-	-
HDGNIKPO_01154	3.2e-11	-	-	-	-	-	-	-	-
HDGNIKPO_01155	4.38e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HDGNIKPO_01160	2.24e-53	-	-	-	S	-	-	-	Siphovirus Gp157
HDGNIKPO_01161	3.9e-221	-	-	-	S	-	-	-	helicase activity
HDGNIKPO_01162	3.64e-68	-	-	-	L	-	-	-	AAA domain
HDGNIKPO_01163	3.52e-28	-	-	-	-	-	-	-	-
HDGNIKPO_01164	1.74e-97	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HDGNIKPO_01165	4.51e-166	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
HDGNIKPO_01166	1.34e-52	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HDGNIKPO_01167	1.24e-24	-	-	-	-	-	-	-	-
HDGNIKPO_01169	5.93e-38	-	-	-	S	-	-	-	YopX protein
HDGNIKPO_01170	7.73e-51	-	-	-	-	-	-	-	-
HDGNIKPO_01171	4.66e-21	-	-	-	-	-	-	-	-
HDGNIKPO_01173	4.99e-44	-	-	-	-	-	-	-	-
HDGNIKPO_01177	8.83e-35	-	-	-	V	-	-	-	HNH nucleases
HDGNIKPO_01180	2.47e-17	-	-	-	-	-	-	-	-
HDGNIKPO_01181	3.27e-224	-	-	-	S	-	-	-	Phage Terminase
HDGNIKPO_01182	4.37e-129	-	-	-	S	-	-	-	Phage portal protein
HDGNIKPO_01183	1.15e-70	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
HDGNIKPO_01184	1.05e-139	-	-	-	S	-	-	-	Phage capsid family
HDGNIKPO_01185	1.43e-24	-	-	-	-	-	-	-	-
HDGNIKPO_01186	3.04e-32	-	-	-	-	-	-	-	-
HDGNIKPO_01187	1.32e-44	-	-	-	-	-	-	-	-
HDGNIKPO_01188	5.64e-30	-	-	-	-	-	-	-	-
HDGNIKPO_01189	7.59e-44	-	-	-	S	-	-	-	Phage tail tube protein
HDGNIKPO_01191	1.59e-213	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HDGNIKPO_01193	2.17e-97	-	-	-	L	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDGNIKPO_01194	1.75e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
HDGNIKPO_01196	4.34e-55	-	-	-	-	-	-	-	-
HDGNIKPO_01198	1.78e-07	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
HDGNIKPO_01199	1.61e-135	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDGNIKPO_01201	4.29e-87	-	-	-	-	-	-	-	-
HDGNIKPO_01202	9.03e-16	-	-	-	-	-	-	-	-
HDGNIKPO_01203	3.89e-237	-	-	-	-	-	-	-	-
HDGNIKPO_01204	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HDGNIKPO_01205	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HDGNIKPO_01206	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HDGNIKPO_01207	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDGNIKPO_01208	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HDGNIKPO_01209	5.16e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HDGNIKPO_01210	9.14e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HDGNIKPO_01211	1.79e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HDGNIKPO_01212	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HDGNIKPO_01213	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HDGNIKPO_01214	2.69e-316	dinF	-	-	V	-	-	-	MatE
HDGNIKPO_01215	1.79e-42	-	-	-	-	-	-	-	-
HDGNIKPO_01218	3.48e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HDGNIKPO_01219	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HDGNIKPO_01220	4.64e-106	-	-	-	-	-	-	-	-
HDGNIKPO_01221	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HDGNIKPO_01222	6.25e-138	-	-	-	-	-	-	-	-
HDGNIKPO_01223	0.0	celR	-	-	K	-	-	-	PRD domain
HDGNIKPO_01224	2.7e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HDGNIKPO_01225	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HDGNIKPO_01226	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDGNIKPO_01227	4.29e-310	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_01228	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_01229	1.28e-263	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HDGNIKPO_01230	9.94e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HDGNIKPO_01231	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDGNIKPO_01232	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HDGNIKPO_01233	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HDGNIKPO_01234	2.77e-271	arcT	-	-	E	-	-	-	Aminotransferase
HDGNIKPO_01235	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDGNIKPO_01236	2.43e-18	-	-	-	-	-	-	-	-
HDGNIKPO_01237	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HDGNIKPO_01238	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HDGNIKPO_01239	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HDGNIKPO_01240	0.0	yhaN	-	-	L	-	-	-	AAA domain
HDGNIKPO_01241	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDGNIKPO_01242	7.82e-278	-	-	-	-	-	-	-	-
HDGNIKPO_01243	1.39e-232	-	-	-	M	-	-	-	Peptidase family S41
HDGNIKPO_01244	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HDGNIKPO_01245	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDGNIKPO_01246	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDGNIKPO_01247	3e-127	-	-	-	-	-	-	-	-
HDGNIKPO_01248	3.36e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HDGNIKPO_01249	5.27e-203	-	-	-	T	-	-	-	Histidine kinase
HDGNIKPO_01250	1.73e-134	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HDGNIKPO_01251	7.93e-79	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
HDGNIKPO_01252	2.26e-167	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HDGNIKPO_01253	1.18e-100	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HDGNIKPO_01254	3.3e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HDGNIKPO_01255	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDGNIKPO_01256	5.72e-90	-	-	-	S	-	-	-	NUDIX domain
HDGNIKPO_01257	0.0	-	-	-	S	-	-	-	membrane
HDGNIKPO_01258	1.22e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDGNIKPO_01259	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HDGNIKPO_01260	5.12e-285	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HDGNIKPO_01261	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HDGNIKPO_01262	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HDGNIKPO_01263	3.39e-138	-	-	-	-	-	-	-	-
HDGNIKPO_01264	2.71e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HDGNIKPO_01265	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_01266	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HDGNIKPO_01267	0.0	-	-	-	-	-	-	-	-
HDGNIKPO_01268	4.75e-80	-	-	-	-	-	-	-	-
HDGNIKPO_01269	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
HDGNIKPO_01270	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_01271	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_01272	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDGNIKPO_01273	7.9e-72	-	-	-	-	-	-	-	-
HDGNIKPO_01274	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HDGNIKPO_01275	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_01276	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_01277	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HDGNIKPO_01278	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDGNIKPO_01279	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HDGNIKPO_01280	1.45e-145	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDGNIKPO_01281	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDGNIKPO_01282	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HDGNIKPO_01283	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HDGNIKPO_01284	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HDGNIKPO_01285	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HDGNIKPO_01286	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HDGNIKPO_01287	8.63e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HDGNIKPO_01288	1.83e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDGNIKPO_01289	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HDGNIKPO_01290	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HDGNIKPO_01291	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HDGNIKPO_01292	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HDGNIKPO_01293	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HDGNIKPO_01294	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDGNIKPO_01295	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDGNIKPO_01296	3.88e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDGNIKPO_01297	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDGNIKPO_01298	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HDGNIKPO_01299	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HDGNIKPO_01300	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDGNIKPO_01301	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDGNIKPO_01302	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HDGNIKPO_01303	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDGNIKPO_01304	2.76e-74	-	-	-	-	-	-	-	-
HDGNIKPO_01305	8.2e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HDGNIKPO_01306	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDGNIKPO_01307	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDGNIKPO_01308	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HDGNIKPO_01309	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HDGNIKPO_01310	1.81e-113	-	-	-	-	-	-	-	-
HDGNIKPO_01311	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HDGNIKPO_01312	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HDGNIKPO_01313	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HDGNIKPO_01314	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDGNIKPO_01315	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HDGNIKPO_01316	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDGNIKPO_01317	6.65e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HDGNIKPO_01318	3.55e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HDGNIKPO_01319	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HDGNIKPO_01320	1.3e-125	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HDGNIKPO_01321	8.93e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDGNIKPO_01322	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDGNIKPO_01323	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HDGNIKPO_01324	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HDGNIKPO_01325	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDGNIKPO_01326	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HDGNIKPO_01327	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HDGNIKPO_01328	2.36e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDGNIKPO_01329	1.21e-129	-	-	-	S	-	-	-	SdpI/YhfL protein family
HDGNIKPO_01330	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDGNIKPO_01331	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HDGNIKPO_01332	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDGNIKPO_01333	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDGNIKPO_01334	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDGNIKPO_01335	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDGNIKPO_01336	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDGNIKPO_01337	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDGNIKPO_01338	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HDGNIKPO_01339	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDGNIKPO_01340	9.72e-146	-	-	-	S	-	-	-	membrane
HDGNIKPO_01341	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HDGNIKPO_01342	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HDGNIKPO_01343	0.0	-	-	-	S	-	-	-	membrane
HDGNIKPO_01344	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDGNIKPO_01345	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HDGNIKPO_01346	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDGNIKPO_01347	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HDGNIKPO_01348	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HDGNIKPO_01349	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HDGNIKPO_01350	4.65e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HDGNIKPO_01351	6.68e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HDGNIKPO_01352	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HDGNIKPO_01353	1.83e-177	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HDGNIKPO_01354	1.33e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDGNIKPO_01355	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HDGNIKPO_01356	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HDGNIKPO_01357	7.21e-205	-	-	-	-	-	-	-	-
HDGNIKPO_01358	1.34e-232	-	-	-	-	-	-	-	-
HDGNIKPO_01359	3.55e-127	-	-	-	S	-	-	-	Protein conserved in bacteria
HDGNIKPO_01360	1.87e-74	-	-	-	-	-	-	-	-
HDGNIKPO_01361	2.97e-41	-	-	-	-	-	-	-	-
HDGNIKPO_01364	9.81e-27	-	-	-	-	-	-	-	-
HDGNIKPO_01365	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_01366	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HDGNIKPO_01367	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HDGNIKPO_01368	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HDGNIKPO_01369	1.42e-247	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HDGNIKPO_01370	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDGNIKPO_01371	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HDGNIKPO_01372	9.43e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDGNIKPO_01373	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDGNIKPO_01374	3.99e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDGNIKPO_01375	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDGNIKPO_01376	5.49e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HDGNIKPO_01377	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HDGNIKPO_01378	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HDGNIKPO_01379	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HDGNIKPO_01380	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_01381	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_01382	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDGNIKPO_01383	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDGNIKPO_01384	2.38e-72	-	-	-	-	-	-	-	-
HDGNIKPO_01385	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HDGNIKPO_01386	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDGNIKPO_01387	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDGNIKPO_01388	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDGNIKPO_01389	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDGNIKPO_01390	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDGNIKPO_01391	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HDGNIKPO_01392	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HDGNIKPO_01393	9.9e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDGNIKPO_01394	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HDGNIKPO_01395	2.61e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HDGNIKPO_01396	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HDGNIKPO_01397	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HDGNIKPO_01398	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HDGNIKPO_01399	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDGNIKPO_01400	1.79e-243	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDGNIKPO_01401	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDGNIKPO_01402	7.45e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDGNIKPO_01403	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HDGNIKPO_01404	7.71e-298	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDGNIKPO_01405	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDGNIKPO_01406	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDGNIKPO_01407	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HDGNIKPO_01408	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HDGNIKPO_01409	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDGNIKPO_01410	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HDGNIKPO_01411	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDGNIKPO_01412	1.03e-66	-	-	-	-	-	-	-	-
HDGNIKPO_01413	1.57e-151	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HDGNIKPO_01414	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HDGNIKPO_01415	1.1e-112	-	-	-	-	-	-	-	-
HDGNIKPO_01416	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDGNIKPO_01417	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HDGNIKPO_01419	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HDGNIKPO_01420	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HDGNIKPO_01421	1.42e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HDGNIKPO_01422	6.06e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HDGNIKPO_01423	1.51e-140	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HDGNIKPO_01424	1.79e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HDGNIKPO_01425	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HDGNIKPO_01426	1.45e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HDGNIKPO_01427	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HDGNIKPO_01428	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HDGNIKPO_01429	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HDGNIKPO_01430	1.38e-273	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HDGNIKPO_01431	1.56e-251	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HDGNIKPO_01432	2.12e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HDGNIKPO_01433	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDGNIKPO_01434	8.02e-230	yneE	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_01435	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDGNIKPO_01436	1.97e-230	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDGNIKPO_01437	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDGNIKPO_01438	2.97e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HDGNIKPO_01439	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HDGNIKPO_01440	5.38e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDGNIKPO_01441	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDGNIKPO_01442	7.23e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HDGNIKPO_01443	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HDGNIKPO_01444	2.62e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDGNIKPO_01445	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HDGNIKPO_01446	5.4e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HDGNIKPO_01447	1.01e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HDGNIKPO_01448	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HDGNIKPO_01449	1.07e-206	-	-	-	K	-	-	-	LysR substrate binding domain
HDGNIKPO_01450	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HDGNIKPO_01451	2.66e-247	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDGNIKPO_01452	2.46e-120	-	-	-	K	-	-	-	transcriptional regulator
HDGNIKPO_01453	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_01454	6.56e-193	-	-	-	O	-	-	-	Band 7 protein
HDGNIKPO_01455	7.41e-31	-	-	-	L	-	-	-	Pfam:Integrase_AP2
HDGNIKPO_01459	1.19e-13	-	-	-	-	-	-	-	-
HDGNIKPO_01461	2.1e-71	-	-	-	-	-	-	-	-
HDGNIKPO_01462	1.42e-39	-	-	-	-	-	-	-	-
HDGNIKPO_01463	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HDGNIKPO_01464	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HDGNIKPO_01465	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HDGNIKPO_01466	2.05e-55	-	-	-	-	-	-	-	-
HDGNIKPO_01467	4.98e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HDGNIKPO_01468	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDGNIKPO_01469	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HDGNIKPO_01470	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HDGNIKPO_01471	1.51e-48	-	-	-	-	-	-	-	-
HDGNIKPO_01472	5.79e-21	-	-	-	-	-	-	-	-
HDGNIKPO_01473	5.19e-48	-	-	-	S	-	-	-	transglycosylase associated protein
HDGNIKPO_01474	4e-40	-	-	-	S	-	-	-	CsbD-like
HDGNIKPO_01475	1.06e-53	-	-	-	-	-	-	-	-
HDGNIKPO_01476	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HDGNIKPO_01477	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HDGNIKPO_01478	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDGNIKPO_01479	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HDGNIKPO_01480	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HDGNIKPO_01481	1.52e-67	-	-	-	-	-	-	-	-
HDGNIKPO_01482	2.12e-57	-	-	-	-	-	-	-	-
HDGNIKPO_01483	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDGNIKPO_01484	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HDGNIKPO_01485	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDGNIKPO_01486	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HDGNIKPO_01487	2.06e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HDGNIKPO_01488	4.84e-45	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HDGNIKPO_01489	3.14e-239	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HDGNIKPO_01490	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDGNIKPO_01491	5.84e-129	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDGNIKPO_01492	1.01e-249	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDGNIKPO_01493	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HDGNIKPO_01494	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HDGNIKPO_01495	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HDGNIKPO_01496	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HDGNIKPO_01497	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HDGNIKPO_01498	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HDGNIKPO_01499	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HDGNIKPO_01500	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HDGNIKPO_01502	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDGNIKPO_01503	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_01504	1.3e-202	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HDGNIKPO_01505	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HDGNIKPO_01506	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDGNIKPO_01507	3.28e-233	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HDGNIKPO_01508	2.8e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HDGNIKPO_01509	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HDGNIKPO_01510	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDGNIKPO_01511	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HDGNIKPO_01512	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDGNIKPO_01514	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HDGNIKPO_01516	1.7e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HDGNIKPO_01517	1.86e-94	-	-	-	S	-	-	-	SnoaL-like domain
HDGNIKPO_01518	3.2e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HDGNIKPO_01519	2.85e-266	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HDGNIKPO_01520	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDGNIKPO_01521	2.13e-312	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HDGNIKPO_01522	1.44e-234	-	-	-	V	-	-	-	LD-carboxypeptidase
HDGNIKPO_01523	1.99e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HDGNIKPO_01524	3.99e-158	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDGNIKPO_01525	1.37e-248	-	-	-	-	-	-	-	-
HDGNIKPO_01526	1.5e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HDGNIKPO_01527	1.47e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HDGNIKPO_01528	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HDGNIKPO_01529	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HDGNIKPO_01530	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HDGNIKPO_01531	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDGNIKPO_01532	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDGNIKPO_01533	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDGNIKPO_01534	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HDGNIKPO_01535	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDGNIKPO_01536	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HDGNIKPO_01537	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HDGNIKPO_01538	1.9e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HDGNIKPO_01541	1.92e-168	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HDGNIKPO_01542	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HDGNIKPO_01543	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HDGNIKPO_01544	1.87e-117	-	-	-	F	-	-	-	NUDIX domain
HDGNIKPO_01545	6.19e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_01546	9.28e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDGNIKPO_01547	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HDGNIKPO_01548	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_01549	6.44e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HDGNIKPO_01550	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HDGNIKPO_01551	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HDGNIKPO_01552	3.03e-40	-	-	-	-	-	-	-	-
HDGNIKPO_01553	5.59e-64	-	-	-	-	-	-	-	-
HDGNIKPO_01554	6.64e-189	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HDGNIKPO_01555	3.87e-264	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDGNIKPO_01557	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HDGNIKPO_01558	2.98e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HDGNIKPO_01559	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HDGNIKPO_01560	4.31e-312	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDGNIKPO_01561	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_01562	1.3e-174	-	-	-	-	-	-	-	-
HDGNIKPO_01563	7.79e-78	-	-	-	-	-	-	-	-
HDGNIKPO_01564	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HDGNIKPO_01565	6.75e-290	-	-	-	-	-	-	-	-
HDGNIKPO_01566	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HDGNIKPO_01567	2.44e-242	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HDGNIKPO_01568	3.21e-247	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDGNIKPO_01569	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDGNIKPO_01570	6.39e-119	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDGNIKPO_01571	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDGNIKPO_01572	1.86e-303	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDGNIKPO_01573	1.98e-66	-	-	-	-	-	-	-	-
HDGNIKPO_01574	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HDGNIKPO_01575	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDGNIKPO_01576	5.95e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HDGNIKPO_01577	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HDGNIKPO_01578	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDGNIKPO_01579	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HDGNIKPO_01580	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HDGNIKPO_01581	1.56e-227	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_01582	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDGNIKPO_01583	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDGNIKPO_01584	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDGNIKPO_01585	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HDGNIKPO_01586	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDGNIKPO_01587	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDGNIKPO_01588	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HDGNIKPO_01589	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDGNIKPO_01590	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDGNIKPO_01591	1.1e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HDGNIKPO_01592	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDGNIKPO_01593	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDGNIKPO_01595	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HDGNIKPO_01596	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HDGNIKPO_01597	1.23e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HDGNIKPO_01598	2.48e-252	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HDGNIKPO_01599	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_01600	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_01601	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HDGNIKPO_01602	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HDGNIKPO_01603	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HDGNIKPO_01604	2.4e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HDGNIKPO_01605	2.88e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HDGNIKPO_01606	7.35e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDGNIKPO_01607	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDGNIKPO_01608	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_01609	6.46e-109	-	-	-	-	-	-	-	-
HDGNIKPO_01610	8.95e-292	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDGNIKPO_01611	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDGNIKPO_01612	3.71e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDGNIKPO_01613	5.96e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HDGNIKPO_01614	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDGNIKPO_01615	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HDGNIKPO_01616	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HDGNIKPO_01617	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HDGNIKPO_01618	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HDGNIKPO_01619	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HDGNIKPO_01620	3.38e-252	-	-	-	S	-	-	-	Helix-turn-helix domain
HDGNIKPO_01621	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDGNIKPO_01622	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HDGNIKPO_01623	1.51e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDGNIKPO_01624	1.18e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDGNIKPO_01625	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDGNIKPO_01626	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HDGNIKPO_01627	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HDGNIKPO_01628	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HDGNIKPO_01629	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HDGNIKPO_01630	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDGNIKPO_01631	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HDGNIKPO_01632	2.02e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HDGNIKPO_01633	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDGNIKPO_01634	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HDGNIKPO_01635	3.25e-251	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDGNIKPO_01636	8.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HDGNIKPO_01637	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HDGNIKPO_01638	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HDGNIKPO_01639	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_01640	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDGNIKPO_01641	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HDGNIKPO_01642	2.27e-82	-	-	-	P	-	-	-	Rhodanese Homology Domain
HDGNIKPO_01643	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDGNIKPO_01644	1.93e-266	-	-	-	-	-	-	-	-
HDGNIKPO_01645	1.05e-277	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HDGNIKPO_01646	1.51e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDGNIKPO_01647	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HDGNIKPO_01648	2.2e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDGNIKPO_01649	2.66e-306	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HDGNIKPO_01650	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_01651	7.87e-266	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HDGNIKPO_01652	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDGNIKPO_01653	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HDGNIKPO_01654	7.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HDGNIKPO_01655	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HDGNIKPO_01656	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HDGNIKPO_01657	4.88e-147	-	-	-	GM	-	-	-	epimerase
HDGNIKPO_01658	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HDGNIKPO_01659	5.04e-155	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HDGNIKPO_01660	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HDGNIKPO_01661	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDGNIKPO_01662	6.46e-207	-	-	-	S	-	-	-	Alpha beta hydrolase
HDGNIKPO_01663	5.89e-145	-	-	-	GM	-	-	-	NmrA-like family
HDGNIKPO_01664	9.69e-99	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HDGNIKPO_01665	3.86e-205	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_01666	1.04e-218	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HDGNIKPO_01667	1.58e-21	-	-	-	S	-	-	-	Alpha beta hydrolase
HDGNIKPO_01668	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDGNIKPO_01669	9.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HDGNIKPO_01670	7.78e-261	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDGNIKPO_01671	7.05e-172	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HDGNIKPO_01672	3.43e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_01674	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HDGNIKPO_01675	9.55e-95	-	-	-	K	-	-	-	MarR family
HDGNIKPO_01676	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HDGNIKPO_01677	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_01678	2.11e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDGNIKPO_01679	5.21e-254	-	-	-	-	-	-	-	-
HDGNIKPO_01680	2.59e-256	-	-	-	-	-	-	-	-
HDGNIKPO_01681	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_01682	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDGNIKPO_01683	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_01684	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDGNIKPO_01685	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDGNIKPO_01686	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HDGNIKPO_01687	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HDGNIKPO_01688	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HDGNIKPO_01689	4.58e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDGNIKPO_01690	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HDGNIKPO_01691	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDGNIKPO_01692	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HDGNIKPO_01693	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HDGNIKPO_01694	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HDGNIKPO_01695	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDGNIKPO_01696	3.65e-166	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDGNIKPO_01697	7.36e-220	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HDGNIKPO_01698	5.49e-286	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDGNIKPO_01699	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDGNIKPO_01700	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDGNIKPO_01701	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDGNIKPO_01702	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HDGNIKPO_01703	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HDGNIKPO_01704	3.23e-214	-	-	-	G	-	-	-	Fructosamine kinase
HDGNIKPO_01705	5.97e-151	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HDGNIKPO_01706	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDGNIKPO_01707	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDGNIKPO_01708	2.56e-76	-	-	-	-	-	-	-	-
HDGNIKPO_01709	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDGNIKPO_01710	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HDGNIKPO_01711	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HDGNIKPO_01712	4.78e-65	-	-	-	-	-	-	-	-
HDGNIKPO_01713	1.73e-67	-	-	-	-	-	-	-	-
HDGNIKPO_01714	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDGNIKPO_01715	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDGNIKPO_01716	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDGNIKPO_01717	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HDGNIKPO_01718	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDGNIKPO_01719	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HDGNIKPO_01720	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HDGNIKPO_01721	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDGNIKPO_01722	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HDGNIKPO_01723	4.94e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDGNIKPO_01724	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDGNIKPO_01725	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HDGNIKPO_01726	7.56e-242	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HDGNIKPO_01727	6.29e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDGNIKPO_01728	1.45e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDGNIKPO_01729	8.88e-248	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HDGNIKPO_01730	8.18e-303	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDGNIKPO_01731	1.45e-32	-	-	-	-	-	-	-	-
HDGNIKPO_01732	3.2e-78	-	-	-	-	-	-	-	-
HDGNIKPO_01733	7.4e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDGNIKPO_01734	0.0	-	-	-	G	-	-	-	Major Facilitator
HDGNIKPO_01735	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDGNIKPO_01736	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDGNIKPO_01737	5.46e-62	ylxQ	-	-	J	-	-	-	ribosomal protein
HDGNIKPO_01738	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HDGNIKPO_01739	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HDGNIKPO_01740	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HDGNIKPO_01741	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDGNIKPO_01742	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDGNIKPO_01743	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HDGNIKPO_01744	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HDGNIKPO_01745	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDGNIKPO_01746	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDGNIKPO_01747	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HDGNIKPO_01748	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDGNIKPO_01749	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HDGNIKPO_01750	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HDGNIKPO_01751	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDGNIKPO_01752	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HDGNIKPO_01753	1.14e-175	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HDGNIKPO_01754	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HDGNIKPO_01755	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HDGNIKPO_01756	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HDGNIKPO_01757	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDGNIKPO_01758	7.8e-123	-	-	-	-	-	-	-	-
HDGNIKPO_01759	6.35e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HDGNIKPO_01760	1.01e-100	-	-	-	-	-	-	-	-
HDGNIKPO_01761	3.81e-87	-	-	-	-	-	-	-	-
HDGNIKPO_01762	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HDGNIKPO_01763	8.9e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HDGNIKPO_01764	1.89e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HDGNIKPO_01765	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDGNIKPO_01766	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDGNIKPO_01767	2.19e-125	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HDGNIKPO_01768	4.52e-153	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HDGNIKPO_01771	3.19e-50	-	-	-	S	-	-	-	Haemolysin XhlA
HDGNIKPO_01772	3.43e-259	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDGNIKPO_01773	3.02e-72	-	-	-	-	-	-	-	-
HDGNIKPO_01777	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HDGNIKPO_01778	3.23e-290	-	-	-	S	-	-	-	Phage tail protein
HDGNIKPO_01779	0.0	-	-	-	D	-	-	-	domain protein
HDGNIKPO_01780	2.09e-26	-	-	-	-	-	-	-	-
HDGNIKPO_01781	3.88e-75	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HDGNIKPO_01782	1.66e-137	-	-	-	S	-	-	-	Phage tail tube protein
HDGNIKPO_01783	6.66e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HDGNIKPO_01784	1.65e-88	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HDGNIKPO_01785	6.96e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
HDGNIKPO_01786	5.42e-64	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HDGNIKPO_01787	2.01e-269	-	-	-	S	-	-	-	Phage capsid family
HDGNIKPO_01788	5.74e-162	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HDGNIKPO_01789	2.43e-284	-	-	-	S	-	-	-	Phage portal protein
HDGNIKPO_01790	1.64e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HDGNIKPO_01791	0.0	-	-	-	S	-	-	-	Phage Terminase
HDGNIKPO_01792	7.49e-102	-	-	-	S	-	-	-	Phage terminase, small subunit
HDGNIKPO_01795	2.72e-113	-	-	-	L	-	-	-	HNH nucleases
HDGNIKPO_01796	1.01e-17	-	-	-	V	-	-	-	HNH nucleases
HDGNIKPO_01797	3.02e-112	-	-	-	-	-	-	-	-
HDGNIKPO_01798	4.28e-80	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HDGNIKPO_01799	1.19e-61	-	-	-	-	-	-	-	-
HDGNIKPO_01801	4.21e-171	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HDGNIKPO_01802	3.09e-93	-	-	-	L	-	-	-	DnaD domain protein
HDGNIKPO_01805	4.56e-12	-	-	-	-	-	-	-	-
HDGNIKPO_01811	1.22e-33	-	-	-	-	-	-	-	-
HDGNIKPO_01813	2.16e-116	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HDGNIKPO_01815	3.49e-30	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDGNIKPO_01816	6.22e-48	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HDGNIKPO_01821	3.53e-32	-	-	-	-	-	-	-	-
HDGNIKPO_01826	1.55e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HDGNIKPO_01827	2.74e-43	-	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Hydrolase, nudix family
HDGNIKPO_01828	2.41e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HDGNIKPO_01829	1.75e-43	-	-	-	-	-	-	-	-
HDGNIKPO_01830	1.02e-183	-	-	-	Q	-	-	-	Methyltransferase
HDGNIKPO_01831	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HDGNIKPO_01832	2.87e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HDGNIKPO_01833	4.57e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
HDGNIKPO_01834	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDGNIKPO_01835	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HDGNIKPO_01836	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HDGNIKPO_01837	7.93e-177	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDGNIKPO_01838	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDGNIKPO_01839	6.62e-62	-	-	-	-	-	-	-	-
HDGNIKPO_01840	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDGNIKPO_01841	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HDGNIKPO_01842	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDGNIKPO_01843	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HDGNIKPO_01844	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HDGNIKPO_01845	0.0	cps4J	-	-	S	-	-	-	MatE
HDGNIKPO_01846	2.79e-227	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HDGNIKPO_01847	2.32e-298	-	-	-	-	-	-	-	-
HDGNIKPO_01848	1.94e-244	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HDGNIKPO_01849	1.4e-259	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HDGNIKPO_01850	4.7e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HDGNIKPO_01851	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HDGNIKPO_01852	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HDGNIKPO_01853	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HDGNIKPO_01854	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HDGNIKPO_01855	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDGNIKPO_01856	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_01857	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HDGNIKPO_01858	5.12e-31	-	-	-	-	-	-	-	-
HDGNIKPO_01859	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HDGNIKPO_01860	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HDGNIKPO_01861	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HDGNIKPO_01862	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDGNIKPO_01863	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDGNIKPO_01864	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDGNIKPO_01865	3.4e-203	-	-	-	S	-	-	-	Tetratricopeptide repeat
HDGNIKPO_01866	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDGNIKPO_01867	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDGNIKPO_01868	3.84e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDGNIKPO_01869	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDGNIKPO_01870	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HDGNIKPO_01871	5.09e-241	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HDGNIKPO_01872	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HDGNIKPO_01873	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HDGNIKPO_01874	2.56e-162	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HDGNIKPO_01875	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HDGNIKPO_01876	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDGNIKPO_01877	4.98e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HDGNIKPO_01878	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HDGNIKPO_01879	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDGNIKPO_01880	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HDGNIKPO_01881	0.0	-	-	-	-	-	-	-	-
HDGNIKPO_01882	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HDGNIKPO_01883	9.51e-135	-	-	-	-	-	-	-	-
HDGNIKPO_01884	9.43e-259	-	-	-	-	-	-	-	-
HDGNIKPO_01885	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HDGNIKPO_01886	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HDGNIKPO_01887	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HDGNIKPO_01888	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HDGNIKPO_01889	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HDGNIKPO_01890	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDGNIKPO_01891	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HDGNIKPO_01892	7.02e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HDGNIKPO_01893	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDGNIKPO_01894	6.45e-111	-	-	-	-	-	-	-	-
HDGNIKPO_01895	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HDGNIKPO_01896	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDGNIKPO_01897	5.96e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HDGNIKPO_01898	2.16e-39	-	-	-	-	-	-	-	-
HDGNIKPO_01899	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HDGNIKPO_01900	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDGNIKPO_01901	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDGNIKPO_01902	5.87e-155	-	-	-	S	-	-	-	repeat protein
HDGNIKPO_01903	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HDGNIKPO_01904	0.0	-	-	-	N	-	-	-	domain, Protein
HDGNIKPO_01905	1.22e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDGNIKPO_01906	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_01907	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HDGNIKPO_01908	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HDGNIKPO_01909	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDGNIKPO_01910	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HDGNIKPO_01911	2.13e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HDGNIKPO_01912	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDGNIKPO_01913	7.74e-47	-	-	-	-	-	-	-	-
HDGNIKPO_01914	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HDGNIKPO_01915	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDGNIKPO_01916	2.05e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HDGNIKPO_01917	2.57e-47	-	-	-	K	-	-	-	LytTr DNA-binding domain
HDGNIKPO_01918	1.47e-100	-	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HDGNIKPO_01919	3.64e-101	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HDGNIKPO_01920	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDGNIKPO_01921	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HDGNIKPO_01922	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HDGNIKPO_01923	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HDGNIKPO_01924	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDGNIKPO_01925	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDGNIKPO_01926	4.13e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDGNIKPO_01927	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDGNIKPO_01928	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDGNIKPO_01929	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDGNIKPO_01930	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDGNIKPO_01931	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HDGNIKPO_01932	2.85e-75	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HDGNIKPO_01933	2.12e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDGNIKPO_01934	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HDGNIKPO_01935	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HDGNIKPO_01936	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HDGNIKPO_01937	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HDGNIKPO_01938	1.66e-122	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDGNIKPO_01939	1.44e-146	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HDGNIKPO_01940	2.17e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDGNIKPO_01942	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HDGNIKPO_01943	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDGNIKPO_01944	2.24e-262	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HDGNIKPO_01945	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HDGNIKPO_01946	5.57e-247	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HDGNIKPO_01947	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HDGNIKPO_01948	1.09e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HDGNIKPO_01949	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDGNIKPO_01950	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HDGNIKPO_01951	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HDGNIKPO_01952	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HDGNIKPO_01953	2.34e-266	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HDGNIKPO_01954	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDGNIKPO_01955	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDGNIKPO_01956	3.28e-177	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HDGNIKPO_01957	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HDGNIKPO_01958	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_01980	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HDGNIKPO_01981	1.11e-84	-	-	-	-	-	-	-	-
HDGNIKPO_01982	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HDGNIKPO_01983	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDGNIKPO_01984	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HDGNIKPO_01985	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HDGNIKPO_01986	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDGNIKPO_01987	6.53e-115	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HDGNIKPO_01988	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDGNIKPO_01989	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HDGNIKPO_01990	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDGNIKPO_01991	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDGNIKPO_01992	3.68e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HDGNIKPO_01994	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HDGNIKPO_01995	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HDGNIKPO_01996	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HDGNIKPO_01997	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HDGNIKPO_01998	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HDGNIKPO_01999	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HDGNIKPO_02000	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDGNIKPO_02001	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HDGNIKPO_02002	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HDGNIKPO_02003	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HDGNIKPO_02004	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HDGNIKPO_02005	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HDGNIKPO_02006	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDGNIKPO_02007	1.6e-96	-	-	-	-	-	-	-	-
HDGNIKPO_02008	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDGNIKPO_02009	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HDGNIKPO_02010	7.85e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDGNIKPO_02011	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDGNIKPO_02012	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HDGNIKPO_02013	4.53e-122	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HDGNIKPO_02014	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDGNIKPO_02015	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HDGNIKPO_02016	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HDGNIKPO_02017	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HDGNIKPO_02018	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDGNIKPO_02019	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDGNIKPO_02020	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HDGNIKPO_02021	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDGNIKPO_02022	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HDGNIKPO_02023	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDGNIKPO_02024	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDGNIKPO_02025	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HDGNIKPO_02026	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDGNIKPO_02027	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HDGNIKPO_02028	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDGNIKPO_02029	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDGNIKPO_02030	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDGNIKPO_02031	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDGNIKPO_02032	2.07e-118	-	-	-	-	-	-	-	-
HDGNIKPO_02033	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDGNIKPO_02034	2.24e-92	-	-	-	-	-	-	-	-
HDGNIKPO_02035	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDGNIKPO_02036	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDGNIKPO_02037	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HDGNIKPO_02038	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HDGNIKPO_02039	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDGNIKPO_02040	4.47e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HDGNIKPO_02041	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDGNIKPO_02042	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HDGNIKPO_02043	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HDGNIKPO_02044	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HDGNIKPO_02045	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HDGNIKPO_02046	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HDGNIKPO_02047	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02048	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HDGNIKPO_02049	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HDGNIKPO_02050	5.41e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDGNIKPO_02051	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HDGNIKPO_02052	7.58e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HDGNIKPO_02053	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HDGNIKPO_02054	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HDGNIKPO_02055	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HDGNIKPO_02056	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDGNIKPO_02057	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDGNIKPO_02058	4.5e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HDGNIKPO_02059	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_02060	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDGNIKPO_02061	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HDGNIKPO_02062	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDGNIKPO_02063	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HDGNIKPO_02064	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDGNIKPO_02065	1.15e-144	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HDGNIKPO_02066	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDGNIKPO_02067	1.57e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HDGNIKPO_02068	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDGNIKPO_02069	7.24e-291	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HDGNIKPO_02070	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HDGNIKPO_02071	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HDGNIKPO_02072	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HDGNIKPO_02073	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDGNIKPO_02074	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
HDGNIKPO_02075	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HDGNIKPO_02076	2.96e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HDGNIKPO_02077	1.34e-52	-	-	-	-	-	-	-	-
HDGNIKPO_02078	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HDGNIKPO_02079	1.91e-259	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HDGNIKPO_02080	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDGNIKPO_02081	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HDGNIKPO_02082	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HDGNIKPO_02083	1.78e-240	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDGNIKPO_02084	1.88e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HDGNIKPO_02085	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HDGNIKPO_02086	3.54e-190	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HDGNIKPO_02087	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HDGNIKPO_02088	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDGNIKPO_02089	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HDGNIKPO_02090	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HDGNIKPO_02091	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HDGNIKPO_02092	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HDGNIKPO_02093	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HDGNIKPO_02094	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDGNIKPO_02095	1.2e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDGNIKPO_02096	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HDGNIKPO_02097	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDGNIKPO_02098	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDGNIKPO_02099	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDGNIKPO_02100	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDGNIKPO_02101	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDGNIKPO_02102	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDGNIKPO_02103	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HDGNIKPO_02104	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HDGNIKPO_02105	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDGNIKPO_02106	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDGNIKPO_02107	4.39e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDGNIKPO_02108	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDGNIKPO_02109	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDGNIKPO_02110	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HDGNIKPO_02111	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HDGNIKPO_02112	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HDGNIKPO_02113	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HDGNIKPO_02114	1.12e-246	ampC	-	-	V	-	-	-	Beta-lactamase
HDGNIKPO_02115	8.57e-41	-	-	-	-	-	-	-	-
HDGNIKPO_02116	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HDGNIKPO_02117	1.33e-77	-	-	-	-	-	-	-	-
HDGNIKPO_02118	5.37e-182	-	-	-	-	-	-	-	-
HDGNIKPO_02119	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HDGNIKPO_02120	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02121	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDGNIKPO_02122	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HDGNIKPO_02125	1.98e-40	-	-	-	-	-	-	-	-
HDGNIKPO_02127	1.28e-51	-	-	-	-	-	-	-	-
HDGNIKPO_02128	9.28e-58	-	-	-	-	-	-	-	-
HDGNIKPO_02129	1.27e-109	-	-	-	K	-	-	-	MarR family
HDGNIKPO_02130	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HDGNIKPO_02131	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HDGNIKPO_02132	6.58e-24	-	-	-	-	-	-	-	-
HDGNIKPO_02133	3.26e-24	-	-	-	-	-	-	-	-
HDGNIKPO_02134	9.35e-24	-	-	-	-	-	-	-	-
HDGNIKPO_02135	9.35e-24	-	-	-	-	-	-	-	-
HDGNIKPO_02136	9.35e-24	-	-	-	-	-	-	-	-
HDGNIKPO_02137	2.16e-26	-	-	-	-	-	-	-	-
HDGNIKPO_02138	4.63e-24	-	-	-	-	-	-	-	-
HDGNIKPO_02139	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HDGNIKPO_02140	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDGNIKPO_02141	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02142	2.1e-33	-	-	-	-	-	-	-	-
HDGNIKPO_02143	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HDGNIKPO_02144	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HDGNIKPO_02145	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HDGNIKPO_02146	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HDGNIKPO_02147	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HDGNIKPO_02148	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HDGNIKPO_02149	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HDGNIKPO_02150	1.06e-156	-	-	-	EG	-	-	-	EamA-like transporter family
HDGNIKPO_02151	3.44e-39	-	-	-	EG	-	-	-	EamA-like transporter family
HDGNIKPO_02157	3.42e-20	-	-	-	-	-	-	-	-
HDGNIKPO_02158	6.31e-158	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
HDGNIKPO_02162	2.87e-61	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
HDGNIKPO_02165	6.73e-133	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HDGNIKPO_02166	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HDGNIKPO_02167	1.31e-64	-	-	-	-	-	-	-	-
HDGNIKPO_02168	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HDGNIKPO_02169	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HDGNIKPO_02170	2.68e-32	-	-	-	-	-	-	-	-
HDGNIKPO_02172	8.16e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDGNIKPO_02173	4.27e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HDGNIKPO_02174	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HDGNIKPO_02175	2.29e-48	-	-	-	-	-	-	-	-
HDGNIKPO_02176	1.11e-45	-	-	-	-	-	-	-	-
HDGNIKPO_02177	4.86e-279	-	-	-	T	-	-	-	diguanylate cyclase
HDGNIKPO_02178	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HDGNIKPO_02179	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HDGNIKPO_02180	9.95e-108	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDGNIKPO_02181	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_02182	9.2e-62	-	-	-	-	-	-	-	-
HDGNIKPO_02183	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDGNIKPO_02184	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDGNIKPO_02185	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HDGNIKPO_02186	1.75e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HDGNIKPO_02187	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HDGNIKPO_02188	1.26e-212	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HDGNIKPO_02189	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_02190	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDGNIKPO_02191	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02192	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HDGNIKPO_02193	2.34e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HDGNIKPO_02194	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HDGNIKPO_02195	7.09e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDGNIKPO_02196	3.68e-256	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDGNIKPO_02197	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HDGNIKPO_02198	2.49e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HDGNIKPO_02199	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDGNIKPO_02200	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDGNIKPO_02201	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDGNIKPO_02202	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HDGNIKPO_02203	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDGNIKPO_02204	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HDGNIKPO_02205	1.39e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HDGNIKPO_02206	7.54e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HDGNIKPO_02207	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
HDGNIKPO_02208	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HDGNIKPO_02209	1.71e-67	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HDGNIKPO_02210	2.54e-17	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HDGNIKPO_02211	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDGNIKPO_02212	1.35e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDGNIKPO_02213	1.45e-46	-	-	-	-	-	-	-	-
HDGNIKPO_02214	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDGNIKPO_02215	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HDGNIKPO_02216	0.0	-	-	-	M	-	-	-	domain protein
HDGNIKPO_02217	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HDGNIKPO_02218	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDGNIKPO_02219	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HDGNIKPO_02220	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HDGNIKPO_02221	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDGNIKPO_02222	4.32e-247	-	-	-	S	-	-	-	domain, Protein
HDGNIKPO_02223	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HDGNIKPO_02224	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
HDGNIKPO_02225	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HDGNIKPO_02226	2.43e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDGNIKPO_02227	1.91e-198	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HDGNIKPO_02228	1.79e-92	-	-	-	GK	-	-	-	ROK family
HDGNIKPO_02229	1.13e-112	-	-	-	GK	-	-	-	ROK family
HDGNIKPO_02230	2.08e-199	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDGNIKPO_02231	1.18e-172	rdrA	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HDGNIKPO_02232	0.0	pflD	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HDGNIKPO_02233	4.3e-228	-	-	-	K	-	-	-	sugar-binding domain protein
HDGNIKPO_02234	1.81e-160	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HDGNIKPO_02235	2.13e-182	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDGNIKPO_02236	2.89e-224	ccpB	-	-	K	-	-	-	lacI family
HDGNIKPO_02237	1.51e-202	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDGNIKPO_02238	5e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HDGNIKPO_02239	1.89e-254	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HDGNIKPO_02240	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDGNIKPO_02241	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDGNIKPO_02242	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HDGNIKPO_02243	2.66e-172	-	-	-	-	-	-	-	-
HDGNIKPO_02244	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_02245	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HDGNIKPO_02246	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HDGNIKPO_02247	3.25e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDGNIKPO_02248	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HDGNIKPO_02249	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_02250	1.86e-210	-	-	-	-	-	-	-	-
HDGNIKPO_02251	1.23e-75	-	-	-	-	-	-	-	-
HDGNIKPO_02252	1.44e-65	-	-	-	-	-	-	-	-
HDGNIKPO_02253	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDGNIKPO_02254	4.09e-89	-	-	-	-	-	-	-	-
HDGNIKPO_02255	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HDGNIKPO_02256	2.84e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
HDGNIKPO_02257	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HDGNIKPO_02258	3.89e-62	-	-	-	-	-	-	-	-
HDGNIKPO_02259	1.57e-71	-	-	-	-	-	-	-	-
HDGNIKPO_02260	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HDGNIKPO_02261	4.05e-98	-	-	-	-	-	-	-	-
HDGNIKPO_02262	4.15e-78	-	-	-	-	-	-	-	-
HDGNIKPO_02263	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HDGNIKPO_02264	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HDGNIKPO_02265	9.42e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HDGNIKPO_02266	3.82e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HDGNIKPO_02267	5.2e-185	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HDGNIKPO_02268	1.49e-112	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HDGNIKPO_02269	5.87e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HDGNIKPO_02270	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
HDGNIKPO_02271	1.84e-205	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HDGNIKPO_02272	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDGNIKPO_02273	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HDGNIKPO_02274	3.07e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
HDGNIKPO_02275	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HDGNIKPO_02276	3.74e-205	-	-	-	S	-	-	-	Putative esterase
HDGNIKPO_02277	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_02278	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDGNIKPO_02279	1.74e-178	-	-	-	-	-	-	-	-
HDGNIKPO_02280	4.85e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HDGNIKPO_02281	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HDGNIKPO_02282	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HDGNIKPO_02283	5.4e-80	-	-	-	-	-	-	-	-
HDGNIKPO_02284	7.48e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDGNIKPO_02285	2.97e-76	-	-	-	-	-	-	-	-
HDGNIKPO_02286	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HDGNIKPO_02287	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HDGNIKPO_02288	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDGNIKPO_02289	1.17e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_02290	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDGNIKPO_02291	8.91e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HDGNIKPO_02292	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HDGNIKPO_02293	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDGNIKPO_02294	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HDGNIKPO_02295	2.91e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HDGNIKPO_02296	1.46e-131	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDGNIKPO_02297	3.59e-26	-	-	-	-	-	-	-	-
HDGNIKPO_02298	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDGNIKPO_02299	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HDGNIKPO_02300	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HDGNIKPO_02301	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HDGNIKPO_02302	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HDGNIKPO_02303	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HDGNIKPO_02304	5.46e-218	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HDGNIKPO_02305	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDGNIKPO_02306	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDGNIKPO_02307	4.24e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDGNIKPO_02308	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HDGNIKPO_02309	2.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HDGNIKPO_02310	1.95e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDGNIKPO_02311	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HDGNIKPO_02312	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDGNIKPO_02313	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HDGNIKPO_02314	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HDGNIKPO_02315	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HDGNIKPO_02316	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
HDGNIKPO_02317	1.25e-199	-	-	-	T	-	-	-	EAL domain
HDGNIKPO_02318	2.62e-121	-	-	-	-	-	-	-	-
HDGNIKPO_02319	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HDGNIKPO_02320	4.17e-163	-	-	-	E	-	-	-	Methionine synthase
HDGNIKPO_02321	2.71e-280	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HDGNIKPO_02322	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HDGNIKPO_02323	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDGNIKPO_02324	5.35e-246	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HDGNIKPO_02325	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDGNIKPO_02326	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDGNIKPO_02327	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDGNIKPO_02328	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDGNIKPO_02329	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HDGNIKPO_02330	1e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDGNIKPO_02331	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDGNIKPO_02332	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HDGNIKPO_02333	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDGNIKPO_02334	2.01e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HDGNIKPO_02335	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDGNIKPO_02336	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HDGNIKPO_02337	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDGNIKPO_02338	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HDGNIKPO_02339	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02340	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HDGNIKPO_02341	4.76e-56	-	-	-	-	-	-	-	-
HDGNIKPO_02342	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HDGNIKPO_02343	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02344	3.41e-190	-	-	-	-	-	-	-	-
HDGNIKPO_02345	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HDGNIKPO_02346	1.08e-47	-	-	-	-	-	-	-	-
HDGNIKPO_02347	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HDGNIKPO_02348	1.76e-114	-	-	-	-	-	-	-	-
HDGNIKPO_02349	1.4e-65	-	-	-	-	-	-	-	-
HDGNIKPO_02350	4.79e-13	-	-	-	-	-	-	-	-
HDGNIKPO_02351	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HDGNIKPO_02352	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HDGNIKPO_02353	1.52e-151	-	-	-	-	-	-	-	-
HDGNIKPO_02354	1.21e-69	-	-	-	-	-	-	-	-
HDGNIKPO_02356	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HDGNIKPO_02357	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HDGNIKPO_02358	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HDGNIKPO_02359	2.96e-41	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HDGNIKPO_02360	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDGNIKPO_02361	2.28e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HDGNIKPO_02362	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HDGNIKPO_02363	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HDGNIKPO_02364	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HDGNIKPO_02365	9.97e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HDGNIKPO_02366	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
HDGNIKPO_02367	1.58e-285	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HDGNIKPO_02368	3.74e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HDGNIKPO_02369	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDGNIKPO_02370	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_02371	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_02372	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HDGNIKPO_02373	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HDGNIKPO_02374	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_02375	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_02376	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HDGNIKPO_02377	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDGNIKPO_02378	7.44e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HDGNIKPO_02379	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HDGNIKPO_02380	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HDGNIKPO_02381	7.63e-107	-	-	-	-	-	-	-	-
HDGNIKPO_02382	5.06e-196	-	-	-	S	-	-	-	hydrolase
HDGNIKPO_02383	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDGNIKPO_02384	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HDGNIKPO_02385	5.85e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HDGNIKPO_02386	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HDGNIKPO_02387	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HDGNIKPO_02388	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HDGNIKPO_02389	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDGNIKPO_02390	1.08e-81	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDGNIKPO_02391	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HDGNIKPO_02392	4.3e-44	-	-	-	-	-	-	-	-
HDGNIKPO_02393	5.59e-163	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HDGNIKPO_02394	0.0	ycaM	-	-	E	-	-	-	amino acid
HDGNIKPO_02395	2e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDGNIKPO_02396	8.21e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HDGNIKPO_02397	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HDGNIKPO_02398	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_02400	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HDGNIKPO_02401	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HDGNIKPO_02402	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDGNIKPO_02403	1.54e-144	-	-	-	-	-	-	-	-
HDGNIKPO_02404	1.08e-243	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HDGNIKPO_02405	1.57e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
HDGNIKPO_02406	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDGNIKPO_02407	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HDGNIKPO_02408	5.43e-188	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HDGNIKPO_02409	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDGNIKPO_02410	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HDGNIKPO_02411	1.63e-238	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HDGNIKPO_02412	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02413	1.12e-116	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HDGNIKPO_02414	2.33e-237	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HDGNIKPO_02415	5.04e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HDGNIKPO_02416	2.3e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDGNIKPO_02417	9.01e-155	-	-	-	S	-	-	-	Membrane
HDGNIKPO_02418	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HDGNIKPO_02419	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HDGNIKPO_02420	7.15e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HDGNIKPO_02421	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HDGNIKPO_02422	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HDGNIKPO_02423	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HDGNIKPO_02424	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDGNIKPO_02425	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HDGNIKPO_02426	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HDGNIKPO_02427	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HDGNIKPO_02428	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HDGNIKPO_02430	2.72e-90	-	-	-	M	-	-	-	LysM domain
HDGNIKPO_02431	3.92e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HDGNIKPO_02432	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02433	6.76e-270	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HDGNIKPO_02434	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDGNIKPO_02435	2e-73	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HDGNIKPO_02436	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HDGNIKPO_02437	1.27e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HDGNIKPO_02438	5.3e-302	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HDGNIKPO_02439	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HDGNIKPO_02440	1.64e-58	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HDGNIKPO_02441	2.03e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02443	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDGNIKPO_02444	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HDGNIKPO_02445	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDGNIKPO_02446	2.82e-110	-	-	-	-	-	-	-	-
HDGNIKPO_02447	5.14e-111	yvbK	-	-	K	-	-	-	GNAT family
HDGNIKPO_02448	2.8e-49	-	-	-	-	-	-	-	-
HDGNIKPO_02449	2.81e-64	-	-	-	-	-	-	-	-
HDGNIKPO_02450	5.46e-145	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HDGNIKPO_02451	2.65e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HDGNIKPO_02452	1.57e-202	-	-	-	K	-	-	-	LysR substrate binding domain
HDGNIKPO_02453	2.53e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
HDGNIKPO_02454	2.03e-248	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HDGNIKPO_02455	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDGNIKPO_02456	1.15e-179	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HDGNIKPO_02457	2.92e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDGNIKPO_02458	2.47e-97	-	-	-	C	-	-	-	Flavodoxin
HDGNIKPO_02459	1.38e-160	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HDGNIKPO_02460	1.07e-116	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HDGNIKPO_02461	1.83e-111	-	-	-	GM	-	-	-	NAD(P)H-binding
HDGNIKPO_02462	7.86e-138	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HDGNIKPO_02463	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_02465	1.03e-31	-	-	-	C	-	-	-	Flavodoxin
HDGNIKPO_02466	1.69e-08	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDGNIKPO_02467	9.99e-147	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDGNIKPO_02468	2.41e-165	-	-	-	C	-	-	-	Aldo keto reductase
HDGNIKPO_02469	4.02e-181	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HDGNIKPO_02470	3.08e-178	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HDGNIKPO_02471	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
HDGNIKPO_02472	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDGNIKPO_02473	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HDGNIKPO_02474	2.4e-160	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HDGNIKPO_02475	3.2e-105	-	-	-	-	-	-	-	-
HDGNIKPO_02476	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HDGNIKPO_02477	3.45e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HDGNIKPO_02478	1.52e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HDGNIKPO_02479	1e-246	-	-	-	C	-	-	-	Aldo/keto reductase family
HDGNIKPO_02481	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_02482	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_02483	9.09e-314	-	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_02486	1.24e-229	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HDGNIKPO_02487	1.74e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HDGNIKPO_02488	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HDGNIKPO_02489	3.34e-199	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HDGNIKPO_02490	1.06e-138	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDGNIKPO_02491	3.05e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HDGNIKPO_02492	9.53e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HDGNIKPO_02493	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HDGNIKPO_02494	4.68e-190	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HDGNIKPO_02495	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HDGNIKPO_02496	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HDGNIKPO_02497	2.33e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HDGNIKPO_02498	2.67e-220	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDGNIKPO_02499	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HDGNIKPO_02500	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HDGNIKPO_02501	1.58e-203	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDGNIKPO_02502	3.39e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HDGNIKPO_02503	0.0	-	-	-	-	-	-	-	-
HDGNIKPO_02504	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HDGNIKPO_02505	5.02e-117	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDGNIKPO_02506	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HDGNIKPO_02507	2.82e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HDGNIKPO_02508	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDGNIKPO_02509	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HDGNIKPO_02510	1.56e-108	-	-	-	-	-	-	-	-
HDGNIKPO_02511	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDGNIKPO_02512	5.32e-242	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDGNIKPO_02513	2.09e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDGNIKPO_02514	3.7e-30	-	-	-	-	-	-	-	-
HDGNIKPO_02515	1.84e-134	-	-	-	-	-	-	-	-
HDGNIKPO_02516	5.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain
HDGNIKPO_02517	1.24e-313	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HDGNIKPO_02518	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HDGNIKPO_02519	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HDGNIKPO_02520	3.22e-181	-	-	-	S	-	-	-	zinc-ribbon domain
HDGNIKPO_02522	4.29e-50	-	-	-	-	-	-	-	-
HDGNIKPO_02523	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HDGNIKPO_02524	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HDGNIKPO_02525	0.0	-	-	-	I	-	-	-	acetylesterase activity
HDGNIKPO_02526	1.99e-297	-	-	-	M	-	-	-	Collagen binding domain
HDGNIKPO_02527	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
HDGNIKPO_02528	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HDGNIKPO_02529	1.44e-226	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HDGNIKPO_02530	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HDGNIKPO_02531	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDGNIKPO_02532	8.78e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HDGNIKPO_02533	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HDGNIKPO_02534	6.37e-125	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HDGNIKPO_02535	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
HDGNIKPO_02536	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HDGNIKPO_02537	7.52e-139	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HDGNIKPO_02538	4.78e-197	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HDGNIKPO_02539	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_02540	0.0	-	-	-	-	-	-	-	-
HDGNIKPO_02541	3.08e-80	-	-	-	-	-	-	-	-
HDGNIKPO_02542	1.52e-239	-	-	-	S	-	-	-	Cell surface protein
HDGNIKPO_02543	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_02544	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HDGNIKPO_02545	1.61e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_02546	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HDGNIKPO_02547	3.79e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HDGNIKPO_02548	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HDGNIKPO_02549	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HDGNIKPO_02551	1.15e-43	-	-	-	-	-	-	-	-
HDGNIKPO_02552	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HDGNIKPO_02553	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HDGNIKPO_02554	4.08e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDGNIKPO_02555	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HDGNIKPO_02556	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HDGNIKPO_02557	2.87e-61	-	-	-	-	-	-	-	-
HDGNIKPO_02558	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HDGNIKPO_02559	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HDGNIKPO_02560	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HDGNIKPO_02561	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02562	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HDGNIKPO_02563	2.03e-84	-	-	-	-	-	-	-	-
HDGNIKPO_02564	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HDGNIKPO_02565	2.86e-72	-	-	-	-	-	-	-	-
HDGNIKPO_02566	1.02e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
HDGNIKPO_02567	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDGNIKPO_02568	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDGNIKPO_02569	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_02570	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_02571	7.48e-236	-	-	-	GM	-	-	-	Male sterility protein
HDGNIKPO_02572	4.4e-101	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDGNIKPO_02573	4.61e-101	-	-	-	M	-	-	-	LysM domain
HDGNIKPO_02574	3.03e-130	-	-	-	M	-	-	-	Lysin motif
HDGNIKPO_02575	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HDGNIKPO_02576	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HDGNIKPO_02577	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDGNIKPO_02578	3.57e-120	-	-	-	-	-	-	-	-
HDGNIKPO_02579	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HDGNIKPO_02580	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
HDGNIKPO_02581	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDGNIKPO_02582	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HDGNIKPO_02583	1.17e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HDGNIKPO_02584	5.26e-96	-	-	-	-	-	-	-	-
HDGNIKPO_02585	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDGNIKPO_02586	5.37e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HDGNIKPO_02587	2.51e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
HDGNIKPO_02588	1.6e-118	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HDGNIKPO_02589	7.83e-101	yphH	-	-	S	-	-	-	Cupin domain
HDGNIKPO_02590	2.06e-78	-	-	-	I	-	-	-	sulfurtransferase activity
HDGNIKPO_02591	5.44e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HDGNIKPO_02592	8.38e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
HDGNIKPO_02593	2.31e-277	-	-	-	-	-	-	-	-
HDGNIKPO_02594	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_02595	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02596	1.3e-226	-	-	-	O	-	-	-	protein import
HDGNIKPO_02597	1.67e-292	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HDGNIKPO_02598	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
HDGNIKPO_02600	9.38e-91	-	-	-	-	-	-	-	-
HDGNIKPO_02601	1.74e-185	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDGNIKPO_02602	0.0	-	-	-	E	-	-	-	Amino Acid
HDGNIKPO_02603	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HDGNIKPO_02604	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HDGNIKPO_02605	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HDGNIKPO_02606	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HDGNIKPO_02607	1.49e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
HDGNIKPO_02608	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HDGNIKPO_02609	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HDGNIKPO_02610	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HDGNIKPO_02611	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HDGNIKPO_02612	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDGNIKPO_02613	0.0	-	-	-	-	-	-	-	-
HDGNIKPO_02614	2.69e-99	-	-	-	-	-	-	-	-
HDGNIKPO_02615	2.85e-243	-	-	-	S	-	-	-	Cell surface protein
HDGNIKPO_02616	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_02617	4.62e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HDGNIKPO_02618	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HDGNIKPO_02619	1.36e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HDGNIKPO_02620	1.52e-241	ynjC	-	-	S	-	-	-	Cell surface protein
HDGNIKPO_02621	4.48e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_02622	1.47e-83	-	-	-	-	-	-	-	-
HDGNIKPO_02623	1.06e-302	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HDGNIKPO_02624	4.8e-156	-	-	-	-	-	-	-	-
HDGNIKPO_02625	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HDGNIKPO_02626	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HDGNIKPO_02627	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_02628	4.52e-147	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HDGNIKPO_02629	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HDGNIKPO_02630	1.38e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDGNIKPO_02631	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDGNIKPO_02632	1.59e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_02633	2.65e-216	-	-	-	GM	-	-	-	NmrA-like family
HDGNIKPO_02634	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HDGNIKPO_02635	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDGNIKPO_02636	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HDGNIKPO_02637	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDGNIKPO_02638	3.27e-170	-	-	-	S	-	-	-	KR domain
HDGNIKPO_02639	2.46e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_02640	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HDGNIKPO_02641	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HDGNIKPO_02642	1.97e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
HDGNIKPO_02645	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HDGNIKPO_02646	1.08e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_02647	1.42e-218	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HDGNIKPO_02648	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HDGNIKPO_02649	2.58e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDGNIKPO_02650	3.32e-219	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDGNIKPO_02651	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_02652	3.89e-210	-	-	-	GM	-	-	-	NmrA-like family
HDGNIKPO_02653	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HDGNIKPO_02654	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HDGNIKPO_02655	1.83e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HDGNIKPO_02656	3.86e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDGNIKPO_02657	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HDGNIKPO_02658	3.51e-232	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDGNIKPO_02659	1.87e-107	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_02660	2.78e-254	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HDGNIKPO_02661	1.97e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_02662	3.05e-38	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDGNIKPO_02663	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDGNIKPO_02664	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HDGNIKPO_02665	4.54e-202	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HDGNIKPO_02666	2.72e-208	-	-	-	K	-	-	-	LysR substrate binding domain
HDGNIKPO_02667	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDGNIKPO_02668	0.0	-	-	-	S	-	-	-	MucBP domain
HDGNIKPO_02669	8.08e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HDGNIKPO_02670	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_02671	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_02672	2.09e-85	-	-	-	-	-	-	-	-
HDGNIKPO_02673	5.15e-16	-	-	-	-	-	-	-	-
HDGNIKPO_02674	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HDGNIKPO_02675	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HDGNIKPO_02676	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDGNIKPO_02677	8.12e-282	-	-	-	S	-	-	-	Membrane
HDGNIKPO_02678	2.97e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HDGNIKPO_02679	5.35e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HDGNIKPO_02680	1.35e-55	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HDGNIKPO_02681	9.66e-77	-	-	-	-	-	-	-	-
HDGNIKPO_02682	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HDGNIKPO_02683	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HDGNIKPO_02684	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HDGNIKPO_02685	3.64e-47	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDGNIKPO_02686	1.44e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HDGNIKPO_02687	8.09e-142	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HDGNIKPO_02688	1.93e-139	-	-	-	GM	-	-	-	NAD(P)H-binding
HDGNIKPO_02689	5.35e-102	-	-	-	GM	-	-	-	SnoaL-like domain
HDGNIKPO_02690	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
HDGNIKPO_02691	2.52e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HDGNIKPO_02692	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_02693	1.34e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HDGNIKPO_02694	8.53e-45	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HDGNIKPO_02696	6.79e-53	-	-	-	-	-	-	-	-
HDGNIKPO_02697	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDGNIKPO_02698	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HDGNIKPO_02699	7.62e-270	xylR	-	-	GK	-	-	-	ROK family
HDGNIKPO_02700	4.93e-149	-	-	-	-	-	-	-	-
HDGNIKPO_02701	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HDGNIKPO_02702	1.41e-211	-	-	-	-	-	-	-	-
HDGNIKPO_02703	1.66e-259	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HDGNIKPO_02704	5.03e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HDGNIKPO_02705	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HDGNIKPO_02706	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HDGNIKPO_02707	2.12e-72	-	-	-	-	-	-	-	-
HDGNIKPO_02708	1.18e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HDGNIKPO_02709	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HDGNIKPO_02710	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HDGNIKPO_02711	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HDGNIKPO_02712	5.36e-305	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HDGNIKPO_02713	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HDGNIKPO_02714	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HDGNIKPO_02715	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HDGNIKPO_02716	1.1e-143	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDGNIKPO_02717	2.11e-33	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDGNIKPO_02718	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDGNIKPO_02719	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HDGNIKPO_02720	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDGNIKPO_02721	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HDGNIKPO_02722	3.98e-200	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDGNIKPO_02723	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HDGNIKPO_02724	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HDGNIKPO_02725	3.66e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HDGNIKPO_02726	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HDGNIKPO_02727	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HDGNIKPO_02728	5.43e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDGNIKPO_02729	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HDGNIKPO_02730	9.83e-301	-	-	-	EK	-	-	-	Aminotransferase, class I
HDGNIKPO_02731	1.11e-169	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HDGNIKPO_02732	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_02733	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02734	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HDGNIKPO_02735	8.83e-127	-	-	-	KT	-	-	-	response to antibiotic
HDGNIKPO_02736	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HDGNIKPO_02737	6.03e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HDGNIKPO_02738	9.68e-202	-	-	-	S	-	-	-	Putative adhesin
HDGNIKPO_02739	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDGNIKPO_02740	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HDGNIKPO_02741	1.06e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HDGNIKPO_02742	4.35e-262	-	-	-	S	-	-	-	DUF218 domain
HDGNIKPO_02743	9.95e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HDGNIKPO_02744	1.76e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HDGNIKPO_02745	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDGNIKPO_02746	6.26e-101	-	-	-	-	-	-	-	-
HDGNIKPO_02747	5.43e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HDGNIKPO_02748	4.82e-188	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HDGNIKPO_02749	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HDGNIKPO_02750	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HDGNIKPO_02751	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HDGNIKPO_02752	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDGNIKPO_02753	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HDGNIKPO_02754	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDGNIKPO_02755	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HDGNIKPO_02756	2.16e-199	-	-	-	GM	-	-	-	NmrA-like family
HDGNIKPO_02757	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDGNIKPO_02758	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HDGNIKPO_02760	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HDGNIKPO_02761	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HDGNIKPO_02762	2.73e-134	-	-	-	-	-	-	-	-
HDGNIKPO_02763	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HDGNIKPO_02764	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HDGNIKPO_02765	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HDGNIKPO_02766	7.93e-217	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HDGNIKPO_02767	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HDGNIKPO_02768	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HDGNIKPO_02769	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HDGNIKPO_02770	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HDGNIKPO_02771	1.03e-34	-	-	-	-	-	-	-	-
HDGNIKPO_02772	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HDGNIKPO_02773	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HDGNIKPO_02774	1.04e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HDGNIKPO_02775	4.68e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDGNIKPO_02776	5.81e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HDGNIKPO_02777	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HDGNIKPO_02778	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
HDGNIKPO_02779	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDGNIKPO_02780	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDGNIKPO_02781	7.21e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDGNIKPO_02782	1.45e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HDGNIKPO_02783	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDGNIKPO_02785	1.88e-106	-	-	-	-	-	-	-	-
HDGNIKPO_02786	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HDGNIKPO_02788	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HDGNIKPO_02789	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDGNIKPO_02790	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HDGNIKPO_02791	1.01e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HDGNIKPO_02792	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HDGNIKPO_02793	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HDGNIKPO_02794	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HDGNIKPO_02795	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HDGNIKPO_02796	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HDGNIKPO_02797	3.28e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HDGNIKPO_02799	2.77e-30	-	-	-	-	-	-	-	-
HDGNIKPO_02801	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HDGNIKPO_02802	4.79e-272	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HDGNIKPO_02803	4.4e-138	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HDGNIKPO_02804	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HDGNIKPO_02805	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HDGNIKPO_02806	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HDGNIKPO_02807	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDGNIKPO_02808	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HDGNIKPO_02809	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HDGNIKPO_02810	4.41e-316	-	-	-	EGP	-	-	-	Major Facilitator
HDGNIKPO_02812	1.53e-52	-	-	-	-	-	-	-	-
HDGNIKPO_02813	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HDGNIKPO_02814	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HDGNIKPO_02815	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HDGNIKPO_02816	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HDGNIKPO_02817	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDGNIKPO_02818	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HDGNIKPO_02819	1.05e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HDGNIKPO_02820	1.66e-40	-	-	-	FG	-	-	-	HIT domain
HDGNIKPO_02821	3.23e-73	-	-	-	FG	-	-	-	HIT domain
HDGNIKPO_02822	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HDGNIKPO_02823	4.29e-101	-	-	-	-	-	-	-	-
HDGNIKPO_02824	3.73e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDGNIKPO_02825	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HDGNIKPO_02826	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HDGNIKPO_02828	4.21e-158	-	-	-	S	-	-	-	YjbR
HDGNIKPO_02829	5.51e-284	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HDGNIKPO_02830	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HDGNIKPO_02831	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HDGNIKPO_02832	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HDGNIKPO_02833	3.58e-36	-	-	-	S	-	-	-	Belongs to the LOG family
HDGNIKPO_02834	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HDGNIKPO_02835	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDGNIKPO_02836	2.65e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HDGNIKPO_02837	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HDGNIKPO_02838	7.87e-209	-	-	-	GM	-	-	-	NmrA-like family
HDGNIKPO_02839	1.24e-85	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HDGNIKPO_02840	4.06e-93	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HDGNIKPO_02841	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HDGNIKPO_02842	1.7e-70	-	-	-	-	-	-	-	-
HDGNIKPO_02843	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HDGNIKPO_02844	2.11e-82	-	-	-	-	-	-	-	-
HDGNIKPO_02845	9.16e-111	-	-	-	-	-	-	-	-
HDGNIKPO_02846	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HDGNIKPO_02847	4.59e-74	-	-	-	-	-	-	-	-
HDGNIKPO_02848	4.79e-21	-	-	-	-	-	-	-	-
HDGNIKPO_02849	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HDGNIKPO_02850	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HDGNIKPO_02851	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HDGNIKPO_02852	2.66e-155	-	-	-	S	-	-	-	membrane
HDGNIKPO_02853	1.47e-144	-	-	-	S	-	-	-	VIT family
HDGNIKPO_02854	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HDGNIKPO_02855	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HDGNIKPO_02856	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HDGNIKPO_02857	4.26e-54	-	-	-	-	-	-	-	-
HDGNIKPO_02858	8.43e-97	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HDGNIKPO_02859	3.57e-314	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HDGNIKPO_02860	7.21e-35	-	-	-	-	-	-	-	-
HDGNIKPO_02861	4.39e-66	-	-	-	-	-	-	-	-
HDGNIKPO_02862	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HDGNIKPO_02863	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HDGNIKPO_02864	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HDGNIKPO_02865	2.44e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HDGNIKPO_02866	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HDGNIKPO_02867	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HDGNIKPO_02868	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HDGNIKPO_02869	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HDGNIKPO_02870	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HDGNIKPO_02871	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HDGNIKPO_02872	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HDGNIKPO_02873	2.07e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HDGNIKPO_02874	1.05e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HDGNIKPO_02875	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDGNIKPO_02876	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HDGNIKPO_02877	2.16e-122	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HDGNIKPO_02878	1.58e-66	-	-	-	-	-	-	-	-
HDGNIKPO_02879	9.81e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HDGNIKPO_02880	0.0	-	-	-	-	-	-	-	-
HDGNIKPO_02881	6.48e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDGNIKPO_02882	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_02883	2.7e-175	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HDGNIKPO_02884	1.31e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HDGNIKPO_02885	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HDGNIKPO_02886	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HDGNIKPO_02887	4.45e-38	-	-	-	-	-	-	-	-
HDGNIKPO_02888	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HDGNIKPO_02889	2.04e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
HDGNIKPO_02890	6.18e-71	-	-	-	-	-	-	-	-
HDGNIKPO_02891	9.96e-82	-	-	-	-	-	-	-	-
HDGNIKPO_02894	6.57e-84	-	-	-	V	-	-	-	VanZ like family
HDGNIKPO_02896	1.17e-15	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HDGNIKPO_02897	1.53e-139	-	-	-	-	-	-	-	-
HDGNIKPO_02898	2.56e-70	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HDGNIKPO_02899	5.87e-207	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HDGNIKPO_02900	2.36e-136	-	-	-	K	-	-	-	transcriptional regulator
HDGNIKPO_02901	2.5e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HDGNIKPO_02902	4.86e-174	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HDGNIKPO_02903	7.76e-168	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HDGNIKPO_02904	1.77e-235	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HDGNIKPO_02905	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HDGNIKPO_02906	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDGNIKPO_02907	9.52e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HDGNIKPO_02908	6.85e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HDGNIKPO_02909	1.01e-26	-	-	-	-	-	-	-	-
HDGNIKPO_02910	2.03e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HDGNIKPO_02911	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HDGNIKPO_02912	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HDGNIKPO_02913	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HDGNIKPO_02914	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDGNIKPO_02915	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HDGNIKPO_02916	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HDGNIKPO_02917	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HDGNIKPO_02918	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_02919	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HDGNIKPO_02920	1.58e-59	-	-	-	-	-	-	-	-
HDGNIKPO_02921	7.01e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HDGNIKPO_02922	1.03e-65	-	-	-	-	-	-	-	-
HDGNIKPO_02923	4.16e-314	-	-	-	S	-	-	-	Putative metallopeptidase domain
HDGNIKPO_02924	4.03e-283	-	-	-	S	-	-	-	associated with various cellular activities
HDGNIKPO_02925	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HDGNIKPO_02926	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HDGNIKPO_02927	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HDGNIKPO_02928	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HDGNIKPO_02929	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HDGNIKPO_02930	4.73e-242	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HDGNIKPO_02931	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HDGNIKPO_02932	8.69e-295	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HDGNIKPO_02933	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HDGNIKPO_02934	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HDGNIKPO_02935	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDGNIKPO_02936	9.21e-142	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HDGNIKPO_02937	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HDGNIKPO_02938	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HDGNIKPO_02939	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HDGNIKPO_02940	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDGNIKPO_02941	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDGNIKPO_02942	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HDGNIKPO_02943	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HDGNIKPO_02944	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HDGNIKPO_02945	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HDGNIKPO_02946	4.27e-253	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HDGNIKPO_02947	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HDGNIKPO_02948	8.93e-249	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HDGNIKPO_02949	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HDGNIKPO_02950	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HDGNIKPO_02951	2.49e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDGNIKPO_02952	6.76e-168	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDGNIKPO_02953	4.63e-275	-	-	-	G	-	-	-	Transporter
HDGNIKPO_02954	1.66e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDGNIKPO_02955	5.79e-209	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HDGNIKPO_02956	4.74e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
HDGNIKPO_02957	2.09e-83	-	-	-	-	-	-	-	-
HDGNIKPO_02958	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
HDGNIKPO_02959	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HDGNIKPO_02960	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGNIKPO_02961	3.06e-212	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDGNIKPO_02962	1.58e-207	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HDGNIKPO_02963	1.94e-270	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HDGNIKPO_02964	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_02965	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDGNIKPO_02966	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDGNIKPO_02967	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_02968	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_02969	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HDGNIKPO_02970	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HDGNIKPO_02971	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HDGNIKPO_02972	2.66e-222	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HDGNIKPO_02973	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HDGNIKPO_02974	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HDGNIKPO_02976	1.15e-236	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDGNIKPO_02977	9e-187	yxeH	-	-	S	-	-	-	hydrolase
HDGNIKPO_02978	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDGNIKPO_02979	8.34e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HDGNIKPO_02980	1.43e-306	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HDGNIKPO_02981	2.97e-60	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HDGNIKPO_02982	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDGNIKPO_02983	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDGNIKPO_02984	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HDGNIKPO_02985	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HDGNIKPO_02986	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HDGNIKPO_02987	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HDGNIKPO_02988	1.1e-103	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDGNIKPO_02989	3.05e-161	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HDGNIKPO_02990	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HDGNIKPO_02991	1.09e-66	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDGNIKPO_02992	4.84e-14	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDGNIKPO_02993	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HDGNIKPO_02994	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HDGNIKPO_02995	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HDGNIKPO_02996	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HDGNIKPO_02997	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HDGNIKPO_02998	1.2e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HDGNIKPO_02999	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HDGNIKPO_03000	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDGNIKPO_03001	2.54e-210	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDGNIKPO_03002	1.65e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HDGNIKPO_03003	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDGNIKPO_03004	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDGNIKPO_03005	3.83e-174	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HDGNIKPO_03006	2.93e-200	nanK	-	-	GK	-	-	-	ROK family
HDGNIKPO_03007	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HDGNIKPO_03008	1.01e-157	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HDGNIKPO_03009	2.28e-291	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HDGNIKPO_03010	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HDGNIKPO_03011	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HDGNIKPO_03012	1.06e-16	-	-	-	-	-	-	-	-
HDGNIKPO_03013	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HDGNIKPO_03014	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HDGNIKPO_03015	5.38e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HDGNIKPO_03016	4.29e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HDGNIKPO_03017	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HDGNIKPO_03018	9.62e-19	-	-	-	-	-	-	-	-
HDGNIKPO_03019	6.12e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HDGNIKPO_03020	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HDGNIKPO_03022	1.97e-256	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HDGNIKPO_03023	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDGNIKPO_03024	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_03025	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HDGNIKPO_03026	4.04e-94	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HDGNIKPO_03027	1.45e-162	-	-	-	S	-	-	-	Membrane
HDGNIKPO_03028	1.31e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HDGNIKPO_03029	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
HDGNIKPO_03030	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HDGNIKPO_03031	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HDGNIKPO_03032	4.67e-314	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HDGNIKPO_03033	8.35e-230	rhaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDGNIKPO_03034	1.05e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HDGNIKPO_03035	1.36e-173	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_03036	8.3e-39	-	-	-	L	ko:K07487	-	ko00000	Transposase
HDGNIKPO_03037	1.82e-208	-	-	-	L	ko:K07487	-	ko00000	Transposase
HDGNIKPO_03038	3.69e-112	-	-	-	L	ko:K07487	-	ko00000	Transposase
HDGNIKPO_03040	1.08e-208	-	-	-	-	-	-	-	-
HDGNIKPO_03041	2.76e-28	-	-	-	S	-	-	-	Cell surface protein
HDGNIKPO_03044	2.03e-12	-	-	-	L	-	-	-	Helix-turn-helix domain
HDGNIKPO_03045	4.32e-16	-	-	-	L	-	-	-	Helix-turn-helix domain
HDGNIKPO_03046	2.28e-22	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HDGNIKPO_03047	4.6e-18	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDGNIKPO_03049	3.07e-06	-	-	-	D	-	-	-	Mycoplasma protein of unknown function, DUF285
HDGNIKPO_03051	2.72e-70	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDGNIKPO_03053	2.12e-27	-	-	-	L	ko:K07487	-	ko00000	Transposase
HDGNIKPO_03054	9.07e-22	-	-	-	L	ko:K07487	-	ko00000	Transposase
HDGNIKPO_03055	4.24e-144	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HDGNIKPO_03056	9.95e-122	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HDGNIKPO_03057	3.95e-92	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HDGNIKPO_03058	0.0	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HDGNIKPO_03059	4.02e-205	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HDGNIKPO_03060	0.0	-	2.3.1.204, 3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
HDGNIKPO_03061	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HDGNIKPO_03062	2.66e-248	-	-	-	K	-	-	-	Transcriptional regulator
HDGNIKPO_03063	0.0	ypdD	-	-	G	-	-	-	Glycosyl hydrolase family 92
HDGNIKPO_03064	6.06e-273	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HDGNIKPO_03065	3.76e-212	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HDGNIKPO_03066	0.0	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HDGNIKPO_03067	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HDGNIKPO_03068	1.71e-139	ypcB	-	-	S	-	-	-	integral membrane protein
HDGNIKPO_03069	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HDGNIKPO_03070	0.0	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Domain of unknown function (DUF3502)
HDGNIKPO_03071	6.47e-213	lplC	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDGNIKPO_03072	1.29e-231	ypdA	-	-	U	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HDGNIKPO_03073	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HDGNIKPO_03074	1.76e-119	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDGNIKPO_03075	6.12e-48	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HDGNIKPO_03076	0.0	mdlA2	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HDGNIKPO_03077	0.0	yknV	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HDGNIKPO_03078	1.48e-247	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HDGNIKPO_03079	1.91e-201	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HDGNIKPO_03080	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HDGNIKPO_03081	2.5e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HDGNIKPO_03082	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HDGNIKPO_03083	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HDGNIKPO_03084	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HDGNIKPO_03085	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HDGNIKPO_03086	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HDGNIKPO_03087	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HDGNIKPO_03088	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDGNIKPO_03089	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HDGNIKPO_03090	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HDGNIKPO_03091	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HDGNIKPO_03092	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HDGNIKPO_03093	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HDGNIKPO_03094	1.44e-185	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HDGNIKPO_03095	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HDGNIKPO_03096	3.3e-202	degV1	-	-	S	-	-	-	DegV family
HDGNIKPO_03097	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HDGNIKPO_03098	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HDGNIKPO_03100	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HDGNIKPO_03101	0.0	-	-	-	-	-	-	-	-
HDGNIKPO_03103	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HDGNIKPO_03104	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HDGNIKPO_03105	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDGNIKPO_03106	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDGNIKPO_03107	2.37e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HDGNIKPO_03108	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HDGNIKPO_03109	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HDGNIKPO_03110	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDGNIKPO_03111	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDGNIKPO_03112	1.18e-123	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HDGNIKPO_03113	9.37e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDGNIKPO_03114	1.02e-153	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HDGNIKPO_03115	1.33e-108	-	-	-	S	-	-	-	Pfam:DUF3816
HDGNIKPO_03116	2.07e-103	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDGNIKPO_03117	2.37e-29	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HDGNIKPO_03118	6.33e-225	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HDGNIKPO_03120	5e-224	arsB	-	-	U	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HDGNIKPO_03121	4.68e-43	-	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HDGNIKPO_03122	7.14e-180	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDGNIKPO_03123	9.03e-241	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HDGNIKPO_03124	3.47e-40	-	-	-	-	-	-	-	-
HDGNIKPO_03125	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDGNIKPO_03126	1.16e-84	-	-	-	-	-	-	-	-
HDGNIKPO_03127	3.82e-192	-	-	-	-	-	-	-	-
HDGNIKPO_03128	8.15e-77	-	-	-	-	-	-	-	-
HDGNIKPO_03129	1.53e-26	-	-	-	-	-	-	-	-
HDGNIKPO_03130	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HDGNIKPO_03131	8.15e-77	-	-	-	-	-	-	-	-
HDGNIKPO_03132	2.03e-67	-	-	-	-	-	-	-	-
HDGNIKPO_03133	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HDGNIKPO_03134	1e-27	-	-	-	-	-	-	-	-
HDGNIKPO_03135	1.36e-51	-	-	-	-	-	-	-	-
HDGNIKPO_03136	1.1e-88	-	-	-	S	-	-	-	protein conserved in bacteria
HDGNIKPO_03137	5.22e-37	-	-	-	-	-	-	-	-
HDGNIKPO_03138	1.39e-175	repA	-	-	S	-	-	-	Replication initiator protein A
HDGNIKPO_03139	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HDGNIKPO_03140	7.85e-29	-	-	-	-	-	-	-	-
HDGNIKPO_03141	1.52e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDGNIKPO_03142	6.13e-127	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HDGNIKPO_03144	6.95e-155	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HDGNIKPO_03145	3e-42	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HDGNIKPO_03146	1.07e-91	-	-	-	L	-	-	-	manually curated
HDGNIKPO_03147	1.42e-126	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein