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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MKMNKICO_00003	6.2e-48	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MKMNKICO_00004	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MKMNKICO_00005	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKMNKICO_00006	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKMNKICO_00007	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKMNKICO_00008	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKMNKICO_00009	1.89e-123	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MKMNKICO_00010	2.99e-275	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MKMNKICO_00011	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MKMNKICO_00012	2.15e-158	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MKMNKICO_00014	6.6e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKMNKICO_00015	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MKMNKICO_00016	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MKMNKICO_00017	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MKMNKICO_00018	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MKMNKICO_00019	2.14e-232	yaaC	-	-	S	-	-	-	YaaC-like Protein
MKMNKICO_00020	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKMNKICO_00021	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKMNKICO_00022	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MKMNKICO_00023	1.68e-25	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKMNKICO_00030	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKMNKICO_00031	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKMNKICO_00032	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MKMNKICO_00033	1.85e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKMNKICO_00034	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MKMNKICO_00035	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKMNKICO_00036	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKMNKICO_00037	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKMNKICO_00038	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKMNKICO_00039	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MKMNKICO_00040	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKMNKICO_00041	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MKMNKICO_00042	5.86e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MKMNKICO_00043	2.58e-192	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MKMNKICO_00044	9.26e-98	-	-	-	S	-	-	-	Bacterial PH domain
MKMNKICO_00045	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MKMNKICO_00046	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MKMNKICO_00047	4.53e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MKMNKICO_00048	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
MKMNKICO_00049	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00050	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKMNKICO_00051	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKMNKICO_00052	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MKMNKICO_00053	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKMNKICO_00054	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKMNKICO_00055	4.68e-184	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MKMNKICO_00056	6.85e-227	ccpB	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00057	9.85e-88	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKMNKICO_00058	1.55e-128	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
MKMNKICO_00059	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
MKMNKICO_00060	4.94e-214	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MKMNKICO_00061	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MKMNKICO_00062	0.0	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_00063	7.09e-136	yyaP	-	-	H	-	-	-	RibD C-terminal domain
MKMNKICO_00064	1.23e-84	-	-	-	S	-	-	-	YjbR
MKMNKICO_00065	1.84e-117	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
MKMNKICO_00066	1.74e-124	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MKMNKICO_00067	2.85e-93	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MKMNKICO_00068	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
MKMNKICO_00069	2.52e-163	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MKMNKICO_00070	1.94e-94	yybC	-	-	-	-	-	-	-
MKMNKICO_00071	1.26e-100	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MKMNKICO_00072	1.31e-210	yybE	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00073	8.32e-275	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_00074	5.67e-162	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
MKMNKICO_00075	2.49e-87	-	-	-	S	-	-	-	SnoaL-like domain
MKMNKICO_00076	2.05e-183	-	-	-	-	-	-	-	-
MKMNKICO_00077	1.46e-140	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
MKMNKICO_00078	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_00080	3.67e-80	-	-	-	-	-	-	-	-
MKMNKICO_00081	4.89e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MKMNKICO_00082	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00083	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MKMNKICO_00085	8.66e-204	yybS	-	-	S	-	-	-	membrane
MKMNKICO_00086	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MKMNKICO_00087	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MKMNKICO_00088	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKMNKICO_00089	4.19e-283	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MKMNKICO_00090	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
MKMNKICO_00092	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MKMNKICO_00093	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MKMNKICO_00094	3.85e-98	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKMNKICO_00095	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKMNKICO_00100	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_00101	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_00102	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00103	2.83e-199	yycI	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00104	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MKMNKICO_00105	1.56e-277	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKMNKICO_00106	2.2e-42	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MKMNKICO_00107	9.34e-98	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MKMNKICO_00108	2.36e-122	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
MKMNKICO_00109	5.58e-216	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MKMNKICO_00110	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MKMNKICO_00111	8.29e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MKMNKICO_00112	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MKMNKICO_00113	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MKMNKICO_00115	1.06e-239	-	-	-	S	-	-	-	aspartate phosphatase
MKMNKICO_00116	5.25e-111	yycN	-	-	K	-	-	-	Acetyltransferase
MKMNKICO_00117	1.68e-169	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MKMNKICO_00118	1.01e-271	yycP	-	-	-	-	-	-	-
MKMNKICO_00119	2.24e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MKMNKICO_00121	1.81e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKMNKICO_00122	8.12e-90	-	-	-	-	-	-	-	-
MKMNKICO_00124	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKMNKICO_00126	1.23e-134	-	-	-	L	-	-	-	reverse transcriptase
MKMNKICO_00127	1.36e-141	-	-	-	S	-	-	-	Caspase domain
MKMNKICO_00128	3.64e-56	-	-	-	S	-	-	-	MazG-like family
MKMNKICO_00129	6.93e-310	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MKMNKICO_00130	0.0	-	-	-	L	-	-	-	AAA domain
MKMNKICO_00131	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MKMNKICO_00132	2.4e-23	-	-	-	-	-	-	-	-
MKMNKICO_00133	1.23e-162	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_00134	8.38e-44	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_00135	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKMNKICO_00136	5.52e-238	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
MKMNKICO_00137	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MKMNKICO_00138	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MKMNKICO_00139	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKMNKICO_00140	5.87e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MKMNKICO_00141	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MKMNKICO_00142	2.56e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
MKMNKICO_00143	1.64e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MKMNKICO_00144	7.3e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
MKMNKICO_00145	7.33e-152	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MKMNKICO_00146	5.96e-77	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MKMNKICO_00147	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKMNKICO_00148	5.01e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_00149	7.9e-130	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MKMNKICO_00150	1e-248	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
MKMNKICO_00151	6.77e-289	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MKMNKICO_00152	4.03e-99	yxaI	-	-	S	-	-	-	membrane protein domain
MKMNKICO_00153	1.96e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
MKMNKICO_00154	1.73e-135	yxaL	-	-	S	-	-	-	PQQ-like domain
MKMNKICO_00155	2.09e-16	yxaI	-	-	S	-	-	-	membrane protein domain
MKMNKICO_00156	2.4e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKMNKICO_00157	1.03e-265	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKMNKICO_00158	8.38e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKMNKICO_00160	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MKMNKICO_00161	2.4e-312	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKMNKICO_00162	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
MKMNKICO_00164	3.52e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MKMNKICO_00165	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MKMNKICO_00166	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKMNKICO_00167	9.89e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MKMNKICO_00168	6.09e-228	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MKMNKICO_00169	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MKMNKICO_00170	1.74e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MKMNKICO_00171	4.68e-295	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MKMNKICO_00172	1.55e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MKMNKICO_00173	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MKMNKICO_00174	1.96e-194	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MKMNKICO_00175	2.83e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MKMNKICO_00176	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_00177	2.7e-231	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_00178	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_00179	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MKMNKICO_00180	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MKMNKICO_00181	4.99e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKMNKICO_00182	6.79e-91	-	-	-	-	-	-	-	-
MKMNKICO_00183	7.57e-28	yxeD	-	-	-	-	-	-	-
MKMNKICO_00184	7.32e-42	yxeE	-	-	-	-	-	-	-
MKMNKICO_00187	1.4e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MKMNKICO_00188	9.11e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MKMNKICO_00189	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKMNKICO_00190	1.54e-121	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKMNKICO_00191	5.02e-185	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MKMNKICO_00192	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MKMNKICO_00193	2.78e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_00194	2.65e-268	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MKMNKICO_00195	1.39e-312	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MKMNKICO_00196	7.72e-256	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
MKMNKICO_00197	1.76e-195	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
MKMNKICO_00198	1.22e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKMNKICO_00199	4.8e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MKMNKICO_00200	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKMNKICO_00201	3.16e-296	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MKMNKICO_00202	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MKMNKICO_00203	8.04e-230	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MKMNKICO_00204	2.61e-298	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MKMNKICO_00205	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MKMNKICO_00206	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MKMNKICO_00207	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MKMNKICO_00208	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MKMNKICO_00209	2.18e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MKMNKICO_00210	4.47e-51	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
MKMNKICO_00211	2.14e-156	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
MKMNKICO_00213	2.81e-26	-	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00215	5.62e-292	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
MKMNKICO_00216	9.25e-103	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
MKMNKICO_00217	1.33e-62	-	-	-	-	-	-	-	-
MKMNKICO_00218	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_00219	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKMNKICO_00220	6.99e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MKMNKICO_00221	2.77e-35	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MKMNKICO_00222	1.24e-113	-	-	-	-	-	-	-	-
MKMNKICO_00224	2.01e-75	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKMNKICO_00225	2.2e-28	-	-	-	-	-	-	-	-
MKMNKICO_00226	8.44e-210	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MKMNKICO_00227	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
MKMNKICO_00228	2.34e-21	-	-	-	S	-	-	-	YxiJ-like protein
MKMNKICO_00229	2.16e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MKMNKICO_00230	1.86e-70	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKMNKICO_00231	2.37e-272	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MKMNKICO_00232	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MKMNKICO_00233	1.09e-291	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MKMNKICO_00234	4.37e-142	-	-	-	-	-	-	-	-
MKMNKICO_00235	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MKMNKICO_00236	1.46e-182	bglS	-	-	M	-	-	-	licheninase activity
MKMNKICO_00237	3.31e-283	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MKMNKICO_00238	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MKMNKICO_00239	5.39e-62	yxiS	-	-	-	-	-	-	-
MKMNKICO_00240	2.83e-131	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MKMNKICO_00241	2.1e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKMNKICO_00242	8.81e-204	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MKMNKICO_00243	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MKMNKICO_00244	3.82e-167	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKMNKICO_00245	5.91e-151	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MKMNKICO_00246	6.8e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MKMNKICO_00247	9.77e-279	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MKMNKICO_00248	1.28e-278	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MKMNKICO_00249	1.43e-111	yxjI	-	-	S	-	-	-	LURP-one-related
MKMNKICO_00252	2.6e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MKMNKICO_00253	4.65e-149	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
MKMNKICO_00254	4.59e-257	-	-	-	T	-	-	-	Signal transduction histidine kinase
MKMNKICO_00255	7.69e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
MKMNKICO_00256	4.98e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKMNKICO_00257	1.17e-98	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MKMNKICO_00258	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKMNKICO_00259	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKMNKICO_00260	3.89e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MKMNKICO_00261	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKMNKICO_00262	6.16e-198	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MKMNKICO_00264	0.0	-	-	-	O	-	-	-	Peptidase family M48
MKMNKICO_00265	3.97e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MKMNKICO_00266	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MKMNKICO_00267	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MKMNKICO_00268	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MKMNKICO_00269	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MKMNKICO_00270	1.52e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKMNKICO_00271	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MKMNKICO_00272	1.06e-123	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKMNKICO_00273	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
MKMNKICO_00274	1.75e-43	-	-	-	-	-	-	-	-
MKMNKICO_00275	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
MKMNKICO_00276	1.65e-210	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_00277	8.58e-174	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKMNKICO_00278	3.23e-270	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKMNKICO_00279	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MKMNKICO_00280	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MKMNKICO_00281	8.94e-28	yxzF	-	-	-	-	-	-	-
MKMNKICO_00282	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MKMNKICO_00283	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MKMNKICO_00284	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKMNKICO_00285	1.18e-67	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_00286	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKMNKICO_00287	3.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MKMNKICO_00288	8e-176	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_00289	8.26e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKMNKICO_00290	1.61e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKMNKICO_00291	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MKMNKICO_00292	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKMNKICO_00293	5.7e-210	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MKMNKICO_00294	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MKMNKICO_00295	2.79e-165	-	-	-	EGP	-	-	-	Permeases of the major facilitator superfamily
MKMNKICO_00296	7.93e-64	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MKMNKICO_00297	5.37e-116	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKMNKICO_00298	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
MKMNKICO_00299	1.56e-297	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKMNKICO_00300	4.18e-113	ywaE	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00301	1.66e-156	ywaF	-	-	S	-	-	-	Integral membrane protein
MKMNKICO_00302	4.41e-215	gspA	-	-	M	-	-	-	General stress
MKMNKICO_00303	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MKMNKICO_00304	1.45e-312	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_00305	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKMNKICO_00306	1.59e-315	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKMNKICO_00307	1.99e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MKMNKICO_00308	4e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MKMNKICO_00309	6.33e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MKMNKICO_00310	1.76e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
MKMNKICO_00311	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MKMNKICO_00312	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MKMNKICO_00313	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00314	1.32e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MKMNKICO_00315	1e-145	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MKMNKICO_00316	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
MKMNKICO_00317	1.98e-245	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
MKMNKICO_00318	2.54e-307	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MKMNKICO_00319	1.26e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MKMNKICO_00320	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKMNKICO_00321	7.41e-65	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
MKMNKICO_00323	4.16e-159	ywcC	-	-	K	-	-	-	transcriptional regulator
MKMNKICO_00324	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
MKMNKICO_00325	1.79e-287	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKMNKICO_00326	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MKMNKICO_00327	5.11e-49	ydaS	-	-	S	-	-	-	membrane
MKMNKICO_00328	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MKMNKICO_00329	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKMNKICO_00330	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MKMNKICO_00331	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MKMNKICO_00332	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MKMNKICO_00333	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MKMNKICO_00334	5.44e-177	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MKMNKICO_00335	3.44e-238	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKMNKICO_00336	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKMNKICO_00338	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MKMNKICO_00339	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
MKMNKICO_00340	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_00341	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MKMNKICO_00342	6.19e-39	ywdA	-	-	-	-	-	-	-
MKMNKICO_00343	7.39e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MKMNKICO_00344	7.92e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MKMNKICO_00345	8.74e-146	ywdD	-	-	-	-	-	-	-
MKMNKICO_00347	1.9e-191	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MKMNKICO_00348	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKMNKICO_00349	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKMNKICO_00350	2.18e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MKMNKICO_00351	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
MKMNKICO_00352	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
MKMNKICO_00353	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MKMNKICO_00354	2.32e-186	spsA	-	-	M	-	-	-	Spore Coat
MKMNKICO_00355	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MKMNKICO_00356	1.85e-284	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MKMNKICO_00357	4.22e-210	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MKMNKICO_00358	1.13e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MKMNKICO_00359	4.64e-169	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MKMNKICO_00360	2.54e-243	spsG	-	-	M	-	-	-	Spore Coat
MKMNKICO_00361	2.6e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MKMNKICO_00362	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MKMNKICO_00363	2.44e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MKMNKICO_00364	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MKMNKICO_00365	1.1e-102	-	-	-	-	-	-	-	-
MKMNKICO_00366	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKMNKICO_00367	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MKMNKICO_00368	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MKMNKICO_00369	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MKMNKICO_00370	3.12e-274	ywfA	-	-	EGP	-	-	-	-transporter
MKMNKICO_00371	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MKMNKICO_00372	7.2e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MKMNKICO_00373	1.56e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_00374	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MKMNKICO_00375	1.85e-266	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MKMNKICO_00376	1.74e-294	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MKMNKICO_00377	2.37e-176	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MKMNKICO_00378	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MKMNKICO_00379	6.8e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MKMNKICO_00380	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_00381	2.51e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MKMNKICO_00382	3.69e-201	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
MKMNKICO_00383	5.39e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MKMNKICO_00384	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MKMNKICO_00385	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MKMNKICO_00386	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
MKMNKICO_00387	1.28e-102	yffB	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00388	6.12e-20	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MKMNKICO_00389	2.66e-263	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MKMNKICO_00391	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKMNKICO_00392	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00393	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MKMNKICO_00394	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
MKMNKICO_00395	5.51e-123	ywhD	-	-	S	-	-	-	YwhD family
MKMNKICO_00396	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MKMNKICO_00397	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MKMNKICO_00398	1.42e-213	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MKMNKICO_00400	1.4e-74	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKMNKICO_00403	1.3e-10	-	-	-	-	-	-	-	-
MKMNKICO_00407	6.56e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MKMNKICO_00408	9.47e-275	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
MKMNKICO_00409	0.0	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
MKMNKICO_00411	0.0	-	-	-	L	-	-	-	Peptidase, M16
MKMNKICO_00412	4.88e-276	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
MKMNKICO_00413	1.46e-298	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
MKMNKICO_00414	1.5e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MKMNKICO_00416	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
MKMNKICO_00417	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
MKMNKICO_00418	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00419	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MKMNKICO_00420	1.4e-272	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MKMNKICO_00421	2.3e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MKMNKICO_00422	1.51e-178	ywiC	-	-	S	-	-	-	YwiC-like protein
MKMNKICO_00423	3.53e-110	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MKMNKICO_00424	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKMNKICO_00425	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MKMNKICO_00426	6.53e-121	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MKMNKICO_00427	1.02e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MKMNKICO_00428	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKMNKICO_00429	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MKMNKICO_00430	7.5e-122	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MKMNKICO_00431	1.32e-57	ywjC	-	-	-	-	-	-	-
MKMNKICO_00432	2.82e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MKMNKICO_00433	9.57e-287	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MKMNKICO_00434	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MKMNKICO_00435	1.65e-266	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
MKMNKICO_00436	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MKMNKICO_00437	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKMNKICO_00438	3.86e-119	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MKMNKICO_00439	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MKMNKICO_00440	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MKMNKICO_00441	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKMNKICO_00442	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKMNKICO_00443	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MKMNKICO_00444	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKMNKICO_00445	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MKMNKICO_00446	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MKMNKICO_00447	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MKMNKICO_00448	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MKMNKICO_00449	6.01e-117	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MKMNKICO_00450	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKMNKICO_00451	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKMNKICO_00452	7.78e-201	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKMNKICO_00454	5.61e-73	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MKMNKICO_00455	1.55e-150	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MKMNKICO_00456	1.04e-99	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MKMNKICO_00457	1.22e-249	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MKMNKICO_00458	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MKMNKICO_00459	1.58e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKMNKICO_00460	1.36e-105	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MKMNKICO_00461	2.9e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MKMNKICO_00462	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKMNKICO_00463	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKMNKICO_00464	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MKMNKICO_00465	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MKMNKICO_00466	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKMNKICO_00467	1.24e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKMNKICO_00468	9.66e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKMNKICO_00469	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKMNKICO_00470	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKMNKICO_00471	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKMNKICO_00472	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MKMNKICO_00473	4.84e-112	ywmA	-	-	-	-	-	-	-
MKMNKICO_00474	4.54e-45	ywzB	-	-	S	-	-	-	membrane
MKMNKICO_00475	2.68e-171	ywmB	-	-	S	-	-	-	TATA-box binding
MKMNKICO_00476	1e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKMNKICO_00477	9.77e-234	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MKMNKICO_00478	1.89e-157	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MKMNKICO_00479	1.02e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MKMNKICO_00481	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MKMNKICO_00482	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MKMNKICO_00483	1.25e-128	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKMNKICO_00484	1.12e-109	ywmF	-	-	S	-	-	-	Peptidase M50
MKMNKICO_00485	1.84e-20	csbD	-	-	K	-	-	-	CsbD-like
MKMNKICO_00487	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MKMNKICO_00488	7.55e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MKMNKICO_00489	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MKMNKICO_00490	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00491	1.02e-145	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MKMNKICO_00492	1.24e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MKMNKICO_00493	2.31e-182	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
MKMNKICO_00494	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKMNKICO_00495	1.43e-91	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MKMNKICO_00496	1.29e-16	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MKMNKICO_00497	5.19e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MKMNKICO_00498	1.3e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MKMNKICO_00499	6.63e-95	ywnJ	-	-	S	-	-	-	VanZ like family
MKMNKICO_00500	3.48e-134	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MKMNKICO_00501	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MKMNKICO_00502	6.5e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MKMNKICO_00503	5.04e-101	-	-	-	-	-	-	-	-
MKMNKICO_00504	1.04e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
MKMNKICO_00505	5.39e-307	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MKMNKICO_00506	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MKMNKICO_00507	7.65e-308	ywoF	-	-	P	-	-	-	Right handed beta helix region
MKMNKICO_00508	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_00509	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
MKMNKICO_00510	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MKMNKICO_00511	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MKMNKICO_00512	9.79e-170	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MKMNKICO_00513	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MKMNKICO_00514	1.5e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MKMNKICO_00515	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MKMNKICO_00516	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MKMNKICO_00517	1.28e-66	ywpD	-	-	T	-	-	-	Histidine kinase
MKMNKICO_00518	2.51e-18	-	-	-	M	-	-	-	cell wall anchor domain
MKMNKICO_00519	6.34e-66	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MKMNKICO_00520	3.59e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
MKMNKICO_00521	3.56e-86	ywpG	-	-	-	-	-	-	-
MKMNKICO_00522	1.04e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MKMNKICO_00523	3.96e-179	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MKMNKICO_00524	1.45e-199	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MKMNKICO_00525	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKMNKICO_00526	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MKMNKICO_00527	3.6e-25	-	-	-	-	-	-	-	-
MKMNKICO_00528	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MKMNKICO_00529	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MKMNKICO_00530	1.18e-178	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MKMNKICO_00531	1.34e-312	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKMNKICO_00532	1.71e-195	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MKMNKICO_00534	4.98e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MKMNKICO_00535	1.95e-297	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MKMNKICO_00536	1.29e-97	-	-	-	-	-	-	-	-
MKMNKICO_00537	2.2e-66	-	-	-	-	-	-	-	-
MKMNKICO_00539	1.13e-126	-	-	-	-	-	-	-	-
MKMNKICO_00540	8.51e-155	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MKMNKICO_00541	3.33e-209	-	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00542	6.11e-129	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
MKMNKICO_00544	3.51e-113	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MKMNKICO_00545	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MKMNKICO_00546	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MKMNKICO_00547	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MKMNKICO_00548	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
MKMNKICO_00549	1.77e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKMNKICO_00550	2.17e-16	-	-	-	-	-	-	-	-
MKMNKICO_00551	2.64e-268	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MKMNKICO_00552	1.37e-194	cotB	-	-	-	ko:K06325	-	ko00000	-
MKMNKICO_00553	2.5e-161	ywrJ	-	-	-	-	-	-	-
MKMNKICO_00554	1.68e-281	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKMNKICO_00555	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
MKMNKICO_00556	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MKMNKICO_00557	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MKMNKICO_00558	8.76e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MKMNKICO_00559	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
MKMNKICO_00560	1.62e-118	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MKMNKICO_00561	9.04e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MKMNKICO_00562	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKMNKICO_00563	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MKMNKICO_00564	4.61e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MKMNKICO_00565	1.85e-206	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKMNKICO_00566	2.68e-227	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MKMNKICO_00567	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MKMNKICO_00568	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MKMNKICO_00569	1.1e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MKMNKICO_00570	2.29e-29	ywtC	-	-	-	-	-	-	-
MKMNKICO_00571	1.37e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MKMNKICO_00572	4.69e-201	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MKMNKICO_00573	1.42e-220	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00574	2.27e-315	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKMNKICO_00575	1.95e-251	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MKMNKICO_00576	3.4e-238	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MKMNKICO_00577	3.12e-310	gerBA	-	-	EG	ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MKMNKICO_00578	9.14e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MKMNKICO_00579	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKMNKICO_00580	1.42e-235	tarL	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKMNKICO_00581	6.69e-110	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	M	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKMNKICO_00582	5.68e-186	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MKMNKICO_00583	1.46e-134	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MKMNKICO_00584	1.01e-129	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKMNKICO_00585	6.82e-111	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MKMNKICO_00586	1.32e-73	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MKMNKICO_00587	6.53e-180	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKMNKICO_00588	4.14e-106	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKMNKICO_00589	7.58e-249	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKMNKICO_00590	5.37e-68	-	-	-	-	-	-	-	-
MKMNKICO_00591	7.8e-102	-	-	-	-	-	-	-	-
MKMNKICO_00592	1.95e-167	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MKMNKICO_00593	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MKMNKICO_00594	2.74e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MKMNKICO_00596	3.05e-119	-	-	-	M	-	-	-	Glycosyl transferases group 1
MKMNKICO_00597	2.94e-103	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKMNKICO_00598	7.71e-277	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MKMNKICO_00599	1.16e-211	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MKMNKICO_00600	9.07e-16	-	-	-	-	-	-	-	-
MKMNKICO_00601	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MKMNKICO_00602	2.25e-265	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MKMNKICO_00603	7e-108	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKMNKICO_00604	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MKMNKICO_00605	2.58e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKMNKICO_00606	5.68e-279	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MKMNKICO_00607	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKMNKICO_00608	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MKMNKICO_00609	5.79e-147	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MKMNKICO_00610	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MKMNKICO_00611	3.69e-300	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MKMNKICO_00612	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MKMNKICO_00613	3.81e-223	yvhJ	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00614	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MKMNKICO_00615	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MKMNKICO_00616	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKMNKICO_00617	1.77e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00618	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MKMNKICO_00619	1.04e-60	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MKMNKICO_00620	7.56e-161	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MKMNKICO_00621	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
MKMNKICO_00622	4.32e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MKMNKICO_00623	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
MKMNKICO_00624	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MKMNKICO_00625	3.8e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MKMNKICO_00626	6.92e-92	yviE	-	-	-	-	-	-	-
MKMNKICO_00627	5e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MKMNKICO_00628	5.02e-39	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MKMNKICO_00629	1.43e-124	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKMNKICO_00630	1.62e-69	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
MKMNKICO_00631	8.97e-313	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MKMNKICO_00632	8.56e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MKMNKICO_00633	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MKMNKICO_00634	9.14e-88	-	-	-	-	-	-	-	-
MKMNKICO_00635	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKMNKICO_00636	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKMNKICO_00637	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKMNKICO_00638	6.5e-185	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKMNKICO_00639	3.23e-75	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MKMNKICO_00640	3.03e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MKMNKICO_00641	1.1e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MKMNKICO_00642	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MKMNKICO_00643	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
MKMNKICO_00644	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKMNKICO_00645	5.24e-296	yvkA	-	-	P	-	-	-	-transporter
MKMNKICO_00646	2.36e-130	yvkB	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00647	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MKMNKICO_00648	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00649	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKMNKICO_00650	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKMNKICO_00651	3.03e-147	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKMNKICO_00652	2.25e-45	yvkN	-	-	-	-	-	-	-
MKMNKICO_00653	3.3e-64	yvlA	-	-	-	-	-	-	-
MKMNKICO_00654	1.85e-217	yvlB	-	-	S	-	-	-	Putative adhesin
MKMNKICO_00655	2.49e-35	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MKMNKICO_00656	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MKMNKICO_00657	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKMNKICO_00658	1.03e-112	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKMNKICO_00659	2.49e-177	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MKMNKICO_00660	9.32e-293	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MKMNKICO_00661	9.4e-110	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKMNKICO_00662	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MKMNKICO_00663	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MKMNKICO_00664	2.12e-166	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKMNKICO_00665	9.39e-277	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKMNKICO_00666	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKMNKICO_00667	2.61e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKMNKICO_00668	3.72e-211	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
MKMNKICO_00669	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MKMNKICO_00670	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MKMNKICO_00671	1.1e-153	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
MKMNKICO_00672	5.03e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MKMNKICO_00673	2.42e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MKMNKICO_00674	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MKMNKICO_00675	3e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKMNKICO_00676	2.87e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MKMNKICO_00677	1.15e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKMNKICO_00678	1.32e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MKMNKICO_00679	5.63e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MKMNKICO_00680	2.61e-146	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MKMNKICO_00681	6.36e-172	-	-	-	-	-	-	-	-
MKMNKICO_00682	0.0	-	-	-	-	-	-	-	-
MKMNKICO_00684	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MKMNKICO_00685	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKMNKICO_00686	2.18e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MKMNKICO_00687	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKMNKICO_00688	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MKMNKICO_00689	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MKMNKICO_00690	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MKMNKICO_00691	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MKMNKICO_00692	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MKMNKICO_00693	8.35e-185	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MKMNKICO_00694	1.37e-45	-	-	-	-	-	-	-	-
MKMNKICO_00695	7.75e-171	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_00696	5.37e-249	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MKMNKICO_00697	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_00698	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MKMNKICO_00699	1.15e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKMNKICO_00700	3.73e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MKMNKICO_00701	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MKMNKICO_00702	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MKMNKICO_00703	2.66e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MKMNKICO_00704	1.54e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00705	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
MKMNKICO_00706	1.63e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MKMNKICO_00707	8.65e-311	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MKMNKICO_00708	6.84e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MKMNKICO_00709	3.96e-197	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MKMNKICO_00710	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
MKMNKICO_00711	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MKMNKICO_00712	2.91e-156	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MKMNKICO_00713	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKMNKICO_00715	9.45e-234	-	-	-	S	-	-	-	Patatin-like phospholipase
MKMNKICO_00716	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
MKMNKICO_00717	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
MKMNKICO_00718	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MKMNKICO_00719	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MKMNKICO_00720	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00721	0.0	ybeC	-	-	E	-	-	-	amino acid
MKMNKICO_00722	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MKMNKICO_00723	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MKMNKICO_00724	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
MKMNKICO_00725	1.69e-160	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MKMNKICO_00726	4.48e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
MKMNKICO_00727	3.13e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MKMNKICO_00729	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MKMNKICO_00730	3.57e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MKMNKICO_00731	1.61e-157	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MKMNKICO_00732	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MKMNKICO_00733	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MKMNKICO_00734	4.5e-281	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MKMNKICO_00735	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKMNKICO_00736	5.9e-277	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MKMNKICO_00737	3.59e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MKMNKICO_00738	3.5e-248	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MKMNKICO_00739	4.13e-254	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MKMNKICO_00740	2.36e-246	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKMNKICO_00741	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKMNKICO_00742	7.83e-140	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MKMNKICO_00743	8.22e-77	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MKMNKICO_00744	1.91e-281	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MKMNKICO_00745	7.54e-241	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MKMNKICO_00746	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
MKMNKICO_00747	3.35e-304	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MKMNKICO_00748	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MKMNKICO_00749	6.85e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MKMNKICO_00750	6.42e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_00751	1.68e-294	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MKMNKICO_00752	2.15e-300	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MKMNKICO_00753	1.1e-193	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MKMNKICO_00754	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
MKMNKICO_00755	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MKMNKICO_00756	2.93e-263	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
MKMNKICO_00757	4.2e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
MKMNKICO_00758	1.7e-208	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MKMNKICO_00759	5.01e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MKMNKICO_00760	7.33e-250	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_00761	2.52e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKMNKICO_00762	2.6e-174	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKMNKICO_00763	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MKMNKICO_00764	2.92e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKMNKICO_00765	1.22e-248	-	-	-	S	-	-	-	Glycosyl hydrolase
MKMNKICO_00766	1.43e-306	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKMNKICO_00767	3.93e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MKMNKICO_00768	5.49e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00770	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKMNKICO_00771	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MKMNKICO_00772	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKMNKICO_00773	9.84e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKMNKICO_00774	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKMNKICO_00775	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MKMNKICO_00776	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKMNKICO_00777	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MKMNKICO_00778	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKMNKICO_00779	6.87e-106	yvbK	-	-	K	-	-	-	acetyltransferase
MKMNKICO_00780	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MKMNKICO_00781	1.61e-156	yvbI	-	-	M	-	-	-	Membrane
MKMNKICO_00782	9.9e-144	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
MKMNKICO_00783	7.95e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MKMNKICO_00784	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MKMNKICO_00785	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKMNKICO_00786	4.63e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKMNKICO_00787	4.11e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKMNKICO_00788	1.37e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKMNKICO_00789	6.63e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MKMNKICO_00790	8.57e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKMNKICO_00791	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKMNKICO_00792	3.37e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKMNKICO_00793	1.31e-143	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKMNKICO_00794	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKMNKICO_00795	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
MKMNKICO_00796	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MKMNKICO_00797	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MKMNKICO_00798	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
MKMNKICO_00799	5.5e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
MKMNKICO_00800	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MKMNKICO_00801	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MKMNKICO_00802	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MKMNKICO_00803	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MKMNKICO_00805	9.32e-181	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_00806	1.17e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKMNKICO_00807	3.52e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MKMNKICO_00808	2.02e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MKMNKICO_00809	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MKMNKICO_00810	2.08e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKMNKICO_00811	1.4e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MKMNKICO_00812	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MKMNKICO_00813	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
MKMNKICO_00814	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MKMNKICO_00815	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MKMNKICO_00816	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
MKMNKICO_00817	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MKMNKICO_00818	2.34e-139	yvgT	-	-	S	-	-	-	membrane
MKMNKICO_00820	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKMNKICO_00821	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKMNKICO_00822	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MKMNKICO_00823	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MKMNKICO_00824	7.97e-113	yvgO	-	-	-	-	-	-	-
MKMNKICO_00825	6.19e-201	yvgN	-	-	S	-	-	-	reductase
MKMNKICO_00826	1.95e-150	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MKMNKICO_00827	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MKMNKICO_00828	4.91e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MKMNKICO_00829	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MKMNKICO_00830	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MKMNKICO_00831	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MKMNKICO_00832	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MKMNKICO_00834	4.45e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKMNKICO_00835	2e-235	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_00836	3.76e-223	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_00837	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKMNKICO_00838	3.61e-231	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
MKMNKICO_00839	3.82e-158	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_00840	3.36e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MKMNKICO_00841	8.13e-85	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MKMNKICO_00842	1.86e-291	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MKMNKICO_00843	4.92e-26	-	-	-	S	-	-	-	YvrJ protein family
MKMNKICO_00844	5.77e-127	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MKMNKICO_00845	5.07e-32	-	-	-	-	-	-	-	-
MKMNKICO_00846	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_00847	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MKMNKICO_00848	3.79e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MKMNKICO_00849	2.12e-181	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_00850	1.21e-217	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MKMNKICO_00851	2.7e-236	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_00852	2.47e-307	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MKMNKICO_00853	4.56e-130	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MKMNKICO_00854	9.24e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_00855	1.51e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MKMNKICO_00856	2.44e-143	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MKMNKICO_00857	2.48e-166	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MKMNKICO_00858	7.65e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MKMNKICO_00859	2.74e-244	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_00860	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKMNKICO_00861	3.48e-249	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MKMNKICO_00862	2.9e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MKMNKICO_00863	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MKMNKICO_00864	4.48e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MKMNKICO_00865	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MKMNKICO_00866	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_00867	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_00868	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_00869	5.56e-305	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKMNKICO_00870	8.76e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
MKMNKICO_00871	1.1e-196	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_00872	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MKMNKICO_00873	2.86e-87	-	-	-	S	-	-	-	YusW-like protein
MKMNKICO_00874	1.06e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKMNKICO_00875	3.66e-64	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MKMNKICO_00876	8.42e-204	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MKMNKICO_00877	8.6e-139	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_00878	2.93e-85	yusQ	-	-	S	-	-	-	Tautomerase enzyme
MKMNKICO_00879	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MKMNKICO_00880	4.47e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MKMNKICO_00881	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
MKMNKICO_00882	2.23e-54	-	-	-	-	-	-	-	-
MKMNKICO_00883	6.98e-211	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MKMNKICO_00884	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
MKMNKICO_00885	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MKMNKICO_00886	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MKMNKICO_00887	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MKMNKICO_00888	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MKMNKICO_00889	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MKMNKICO_00890	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MKMNKICO_00891	7.62e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MKMNKICO_00892	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
MKMNKICO_00893	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MKMNKICO_00894	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKMNKICO_00895	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MKMNKICO_00896	1.01e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MKMNKICO_00897	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKMNKICO_00898	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MKMNKICO_00899	1.23e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MKMNKICO_00900	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKMNKICO_00901	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MKMNKICO_00902	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MKMNKICO_00903	3.35e-56	-	-	-	-	-	-	-	-
MKMNKICO_00905	2.52e-262	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MKMNKICO_00906	8e-51	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MKMNKICO_00907	5.27e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MKMNKICO_00908	1.66e-306	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MKMNKICO_00909	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKMNKICO_00910	4.58e-215	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MKMNKICO_00911	5.54e-208	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MKMNKICO_00912	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MKMNKICO_00913	2.42e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKMNKICO_00914	1.8e-215	bsn	-	-	L	-	-	-	Ribonuclease
MKMNKICO_00915	1.64e-301	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MKMNKICO_00916	8.16e-304	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MKMNKICO_00917	3.56e-234	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MKMNKICO_00918	6.18e-143	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MKMNKICO_00919	4.85e-194	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MKMNKICO_00920	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MKMNKICO_00921	2.42e-122	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MKMNKICO_00922	2.09e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MKMNKICO_00923	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MKMNKICO_00924	1.24e-280	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MKMNKICO_00925	2.82e-298	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
MKMNKICO_00926	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MKMNKICO_00927	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MKMNKICO_00928	1.07e-79	yunG	-	-	-	-	-	-	-
MKMNKICO_00929	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MKMNKICO_00930	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MKMNKICO_00931	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MKMNKICO_00932	3.41e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
MKMNKICO_00933	2.46e-171	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MKMNKICO_00934	3.11e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MKMNKICO_00935	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MKMNKICO_00936	5.47e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKMNKICO_00937	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00938	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MKMNKICO_00939	2.49e-181	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MKMNKICO_00940	3.21e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MKMNKICO_00941	1.55e-253	yutH	-	-	S	-	-	-	Spore coat protein
MKMNKICO_00942	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MKMNKICO_00943	2.4e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MKMNKICO_00944	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKMNKICO_00945	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MKMNKICO_00946	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MKMNKICO_00947	5.44e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00948	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MKMNKICO_00949	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MKMNKICO_00950	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKMNKICO_00951	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKMNKICO_00952	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MKMNKICO_00953	3.98e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKMNKICO_00954	8.15e-149	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
MKMNKICO_00955	4.51e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKMNKICO_00957	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MKMNKICO_00958	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MKMNKICO_00959	1.14e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
MKMNKICO_00960	1.62e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_00961	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MKMNKICO_00962	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MKMNKICO_00963	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MKMNKICO_00964	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MKMNKICO_00965	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MKMNKICO_00966	8.58e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MKMNKICO_00967	5.83e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_00968	7.34e-291	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MKMNKICO_00969	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MKMNKICO_00970	4.47e-228	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MKMNKICO_00971	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKMNKICO_00972	4.08e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MKMNKICO_00973	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MKMNKICO_00974	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MKMNKICO_00975	8.49e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
MKMNKICO_00976	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MKMNKICO_00977	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MKMNKICO_00978	3.93e-270	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MKMNKICO_00979	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MKMNKICO_00980	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MKMNKICO_00981	1.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MKMNKICO_00982	2.04e-169	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_00983	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MKMNKICO_00984	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MKMNKICO_00985	7.71e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
MKMNKICO_00986	5.5e-244	yueF	-	-	S	-	-	-	transporter activity
MKMNKICO_00987	2.05e-42	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MKMNKICO_00988	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
MKMNKICO_00989	3.64e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MKMNKICO_00990	7.71e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MKMNKICO_00991	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKMNKICO_00992	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MKMNKICO_00993	8.73e-09	yuzC	-	-	-	-	-	-	-
MKMNKICO_00994	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
MKMNKICO_00995	8.19e-169	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
MKMNKICO_00997	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_00998	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKMNKICO_00999	2.24e-82	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MKMNKICO_01000	9.92e-78	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MKMNKICO_01001	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKMNKICO_01002	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKMNKICO_01003	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKMNKICO_01004	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKMNKICO_01005	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKMNKICO_01006	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MKMNKICO_01007	1.73e-22	-	-	-	-	-	-	-	-
MKMNKICO_01008	7.99e-309	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
MKMNKICO_01009	6.97e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKMNKICO_01010	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKMNKICO_01011	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_01012	1.28e-253	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MKMNKICO_01013	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MKMNKICO_01014	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MKMNKICO_01015	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MKMNKICO_01016	3.31e-98	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_01017	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MKMNKICO_01018	8.9e-242	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MKMNKICO_01020	8.49e-150	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MKMNKICO_01021	1.44e-90	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MKMNKICO_01022	1.06e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_01023	4.53e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MKMNKICO_01024	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MKMNKICO_01025	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
MKMNKICO_01026	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_01027	3.14e-254	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MKMNKICO_01028	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MKMNKICO_01029	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MKMNKICO_01030	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MKMNKICO_01031	5.34e-289	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MKMNKICO_01032	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MKMNKICO_01034	9.97e-94	yugN	-	-	S	-	-	-	YugN-like family
MKMNKICO_01035	1.45e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MKMNKICO_01036	2.12e-70	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MKMNKICO_01037	1.58e-50	-	-	-	-	-	-	-	-
MKMNKICO_01038	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MKMNKICO_01039	1.03e-299	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKMNKICO_01040	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MKMNKICO_01041	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MKMNKICO_01042	1.44e-47	-	-	-	-	-	-	-	-
MKMNKICO_01043	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MKMNKICO_01044	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKMNKICO_01045	2.64e-294	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKMNKICO_01046	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKMNKICO_01047	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKMNKICO_01048	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
MKMNKICO_01049	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MKMNKICO_01050	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MKMNKICO_01051	2.02e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
MKMNKICO_01052	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
MKMNKICO_01053	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MKMNKICO_01054	7.34e-254	yubA	-	-	S	-	-	-	transporter activity
MKMNKICO_01055	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MKMNKICO_01057	1.61e-112	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
MKMNKICO_01058	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MKMNKICO_01059	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKMNKICO_01060	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
MKMNKICO_01061	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
MKMNKICO_01062	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MKMNKICO_01063	5.83e-118	yuaB	-	-	-	-	-	-	-
MKMNKICO_01064	3.53e-123	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MKMNKICO_01065	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKMNKICO_01066	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MKMNKICO_01067	8.58e-139	yuaD	-	-	-	-	-	-	-
MKMNKICO_01068	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
MKMNKICO_01069	4.82e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MKMNKICO_01070	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MKMNKICO_01071	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
MKMNKICO_01072	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MKMNKICO_01073	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MKMNKICO_01074	9.53e-241	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MKMNKICO_01075	1.33e-310	yoeA	-	-	V	-	-	-	MATE efflux family protein
MKMNKICO_01076	4.13e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MKMNKICO_01078	1.14e-124	-	-	-	L	-	-	-	Integrase
MKMNKICO_01079	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MKMNKICO_01080	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MKMNKICO_01081	1.3e-202	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_01082	4.18e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MKMNKICO_01083	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MKMNKICO_01084	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MKMNKICO_01085	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_01086	1.91e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKMNKICO_01087	2.24e-184	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKMNKICO_01088	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MKMNKICO_01089	7.3e-156	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_01090	1.7e-54	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MKMNKICO_01091	5.79e-171	yoxB	-	-	-	-	-	-	-
MKMNKICO_01092	7.43e-119	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKMNKICO_01093	1.7e-300	-	-	-	S	-	-	-	Arylsulfotransferase (ASST)
MKMNKICO_01094	2.75e-160	-	3.1.1.3	-	I	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	Lipase (class 3)
MKMNKICO_01095	1.84e-299	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MKMNKICO_01096	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MKMNKICO_01097	3.36e-234	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKMNKICO_01098	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKMNKICO_01099	7.24e-45	yoaF	-	-	-	-	-	-	-
MKMNKICO_01102	1.46e-19	-	-	-	-	-	-	-	-
MKMNKICO_01103	2.99e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
MKMNKICO_01104	6.22e-308	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
MKMNKICO_01105	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MKMNKICO_01106	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
MKMNKICO_01107	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
MKMNKICO_01108	1.43e-252	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
MKMNKICO_01109	2.07e-170	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
MKMNKICO_01112	8.89e-293	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MKMNKICO_01114	3.86e-183	yoaP	-	-	K	-	-	-	YoaP-like
MKMNKICO_01115	3.01e-87	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MKMNKICO_01117	1.87e-113	-	-	-	-	-	-	-	-
MKMNKICO_01118	1.04e-217	yoaR	-	-	V	-	-	-	vancomycin resistance protein
MKMNKICO_01119	3.22e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
MKMNKICO_01120	7.19e-41	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_01121	1.57e-188	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
MKMNKICO_01122	1.11e-201	yoaU	-	-	K	-	-	-	LysR substrate binding domain
MKMNKICO_01123	3.7e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
MKMNKICO_01124	1.89e-100	yoaW	-	-	-	-	-	-	-
MKMNKICO_01125	5.94e-148	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
MKMNKICO_01126	2.09e-214	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MKMNKICO_01129	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MKMNKICO_01130	1.07e-156	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MKMNKICO_01131	1e-47	-	-	-	S	-	-	-	TM2 domain
MKMNKICO_01132	7.63e-74	-	-	-	K	-	-	-	Helix-turn-helix
MKMNKICO_01135	7.44e-66	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MKMNKICO_01140	1.56e-12	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MKMNKICO_01144	6.81e-66	-	-	-	S	-	-	-	Tetratricopeptide repeat
MKMNKICO_01145	2.51e-74	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
MKMNKICO_01153	8.49e-265	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MKMNKICO_01155	4.52e-201	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKMNKICO_01156	2.36e-44	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKMNKICO_01157	3.72e-58	-	-	-	-	-	-	-	-
MKMNKICO_01159	5.21e-26	-	-	-	-	-	-	-	-
MKMNKICO_01160	8.94e-13	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MKMNKICO_01161	3.93e-117	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MKMNKICO_01162	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
MKMNKICO_01163	5.21e-71	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MKMNKICO_01164	6.11e-174	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MKMNKICO_01165	3.05e-182	-	-	-	J	-	-	-	FR47-like protein
MKMNKICO_01166	1.53e-127	yobS	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_01167	3.16e-168	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MKMNKICO_01168	1.01e-110	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MKMNKICO_01169	2.3e-226	yobV	-	-	K	-	-	-	WYL domain
MKMNKICO_01170	3.01e-120	yobW	-	-	-	-	-	-	-
MKMNKICO_01171	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MKMNKICO_01172	2.89e-151	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKMNKICO_01173	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MKMNKICO_01174	2.49e-183	-	-	-	-	-	-	-	-
MKMNKICO_01175	1.08e-121	yocC	-	-	-	-	-	-	-
MKMNKICO_01176	6.71e-241	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MKMNKICO_01177	5.67e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MKMNKICO_01178	3.51e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_01179	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKMNKICO_01180	1.67e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MKMNKICO_01181	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKMNKICO_01182	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKMNKICO_01183	4.07e-107	yocK	-	-	T	-	-	-	general stress protein
MKMNKICO_01184	3.02e-70	yocL	-	-	-	-	-	-	-
MKMNKICO_01185	3.93e-41	-	-	-	-	-	-	-	-
MKMNKICO_01186	2.21e-113	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MKMNKICO_01187	2.94e-55	yozN	-	-	-	-	-	-	-
MKMNKICO_01188	1.83e-49	yocN	-	-	-	-	-	-	-
MKMNKICO_01189	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
MKMNKICO_01190	1.91e-42	yozC	-	-	-	-	-	-	-
MKMNKICO_01191	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKMNKICO_01192	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MKMNKICO_01193	3.91e-211	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MKMNKICO_01194	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKMNKICO_01195	4.5e-212	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MKMNKICO_01196	2.59e-264	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MKMNKICO_01197	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MKMNKICO_01198	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MKMNKICO_01199	3.82e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MKMNKICO_01200	7.31e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MKMNKICO_01201	7.5e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MKMNKICO_01202	1.13e-293	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MKMNKICO_01203	1.19e-138	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKMNKICO_01205	2.06e-313	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MKMNKICO_01206	1.01e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKMNKICO_01207	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MKMNKICO_01208	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MKMNKICO_01209	1.07e-57	-	-	-	-	-	-	-	-
MKMNKICO_01210	2.84e-208	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MKMNKICO_01211	7.69e-100	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MKMNKICO_01212	5.59e-14	-	-	-	-	-	-	-	-
MKMNKICO_01213	1.6e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MKMNKICO_01214	3.97e-84	iolK	-	-	S	-	-	-	tautomerase
MKMNKICO_01215	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
MKMNKICO_01216	1.11e-139	yodC	-	-	C	-	-	-	nitroreductase
MKMNKICO_01217	8.86e-145	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MKMNKICO_01218	3.24e-221	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MKMNKICO_01219	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MKMNKICO_01220	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKMNKICO_01221	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MKMNKICO_01222	3.69e-167	yodH	-	-	Q	-	-	-	Methyltransferase
MKMNKICO_01223	8.39e-42	yodI	-	-	-	-	-	-	-
MKMNKICO_01224	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MKMNKICO_01225	1.19e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MKMNKICO_01226	2.08e-12	-	-	-	-	-	-	-	-
MKMNKICO_01227	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
MKMNKICO_01228	2.14e-133	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MKMNKICO_01229	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
MKMNKICO_01231	1.29e-159	yodN	-	-	-	-	-	-	-
MKMNKICO_01232	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MKMNKICO_01233	1.4e-62	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MKMNKICO_01234	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MKMNKICO_01235	1.84e-197	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MKMNKICO_01236	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MKMNKICO_01237	2.71e-152	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MKMNKICO_01238	3.27e-159	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKMNKICO_01239	2.34e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKMNKICO_01241	9.78e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MKMNKICO_01242	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MKMNKICO_01243	3.04e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
MKMNKICO_01244	1.12e-85	cgeA	-	-	-	ko:K06319	-	ko00000	-
MKMNKICO_01245	4.7e-237	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MKMNKICO_01246	2.31e-279	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MKMNKICO_01247	4.75e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MKMNKICO_01248	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MKMNKICO_01249	1.4e-132	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKMNKICO_01250	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
MKMNKICO_01251	9.99e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
MKMNKICO_01252	2.13e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
MKMNKICO_01253	6.8e-129	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_01254	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MKMNKICO_01255	2.77e-140	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MKMNKICO_01256	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MKMNKICO_01257	3.64e-310	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MKMNKICO_01258	1.4e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_01259	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MKMNKICO_01260	1.71e-145	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MKMNKICO_01261	1.21e-124	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKMNKICO_01262	7.27e-203	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKMNKICO_01263	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MKMNKICO_01264	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
MKMNKICO_01265	6.15e-187	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MKMNKICO_01266	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MKMNKICO_01267	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MKMNKICO_01268	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MKMNKICO_01269	3.3e-138	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MKMNKICO_01270	3.13e-114	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MKMNKICO_01271	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MKMNKICO_01272	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MKMNKICO_01273	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MKMNKICO_01274	1.17e-22	degR	-	-	-	-	-	-	-
MKMNKICO_01275	5.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MKMNKICO_01276	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
MKMNKICO_01277	6.45e-173	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MKMNKICO_01278	3.27e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MKMNKICO_01279	7.64e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MKMNKICO_01280	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
MKMNKICO_01281	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
MKMNKICO_01282	1.08e-11	-	-	-	-	-	-	-	-
MKMNKICO_01283	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MKMNKICO_01284	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MKMNKICO_01285	3.33e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MKMNKICO_01286	2.07e-262	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MKMNKICO_01287	3.51e-291	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MKMNKICO_01288	1.65e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKMNKICO_01289	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MKMNKICO_01290	4.09e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MKMNKICO_01291	1.47e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MKMNKICO_01292	2.83e-237	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MKMNKICO_01293	4.51e-237	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MKMNKICO_01294	1.2e-202	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MKMNKICO_01295	1.88e-175	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_01296	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MKMNKICO_01298	2.84e-286	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MKMNKICO_01299	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MKMNKICO_01300	9.4e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MKMNKICO_01301	9.82e-299	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MKMNKICO_01302	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MKMNKICO_01303	1.34e-112	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MKMNKICO_01304	4.33e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MKMNKICO_01305	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
MKMNKICO_01306	2.27e-11	-	-	-	S	-	-	-	YppF-like protein
MKMNKICO_01307	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
MKMNKICO_01310	1.03e-237	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MKMNKICO_01311	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKMNKICO_01312	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MKMNKICO_01313	1.17e-120	ypoC	-	-	-	-	-	-	-
MKMNKICO_01314	5.92e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKMNKICO_01315	1.9e-164	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MKMNKICO_01316	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MKMNKICO_01317	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MKMNKICO_01318	2.27e-103	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_01319	6.21e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MKMNKICO_01320	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MKMNKICO_01321	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MKMNKICO_01322	2.23e-199	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MKMNKICO_01323	9.39e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MKMNKICO_01324	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKMNKICO_01325	3.7e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MKMNKICO_01326	1.65e-265	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MKMNKICO_01327	2.21e-165	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MKMNKICO_01328	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MKMNKICO_01329	6.89e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKMNKICO_01330	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MKMNKICO_01331	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKMNKICO_01332	6.84e-183	ypjB	-	-	S	-	-	-	sporulation protein
MKMNKICO_01333	1.15e-125	ypjA	-	-	S	-	-	-	membrane
MKMNKICO_01334	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MKMNKICO_01335	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MKMNKICO_01336	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MKMNKICO_01337	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MKMNKICO_01338	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MKMNKICO_01339	8.74e-298	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKMNKICO_01340	1.64e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MKMNKICO_01341	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MKMNKICO_01342	2.6e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKMNKICO_01343	5.43e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MKMNKICO_01344	3.12e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MKMNKICO_01345	5.25e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MKMNKICO_01346	8.44e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MKMNKICO_01347	2.48e-229	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKMNKICO_01348	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKMNKICO_01349	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MKMNKICO_01350	7.79e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MKMNKICO_01351	5.88e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MKMNKICO_01352	2.13e-182	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MKMNKICO_01353	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MKMNKICO_01354	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MKMNKICO_01355	3.84e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MKMNKICO_01356	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MKMNKICO_01357	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MKMNKICO_01358	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MKMNKICO_01359	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKMNKICO_01360	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MKMNKICO_01361	2.5e-175	yphF	-	-	-	-	-	-	-
MKMNKICO_01362	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MKMNKICO_01363	6.32e-231	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MKMNKICO_01364	1.72e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MKMNKICO_01365	5.91e-38	ypzH	-	-	-	-	-	-	-
MKMNKICO_01366	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
MKMNKICO_01367	3.87e-134	yphA	-	-	-	-	-	-	-
MKMNKICO_01368	5.6e-12	-	-	-	S	-	-	-	YpzI-like protein
MKMNKICO_01369	1.1e-233	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MKMNKICO_01370	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MKMNKICO_01371	3.91e-144	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MKMNKICO_01372	2.48e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MKMNKICO_01373	8.95e-142	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MKMNKICO_01374	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MKMNKICO_01375	1.1e-204	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MKMNKICO_01376	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MKMNKICO_01377	4.25e-223	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MKMNKICO_01378	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKMNKICO_01379	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKMNKICO_01380	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MKMNKICO_01381	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MKMNKICO_01382	4.22e-139	ypbE	-	-	M	-	-	-	Lysin motif
MKMNKICO_01383	6.13e-129	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MKMNKICO_01384	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKMNKICO_01385	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MKMNKICO_01386	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MKMNKICO_01387	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKMNKICO_01388	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKMNKICO_01389	3.37e-174	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MKMNKICO_01390	1.49e-254	rsiX	-	-	-	-	-	-	-
MKMNKICO_01391	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKMNKICO_01392	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_01393	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_01394	1.34e-278	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MKMNKICO_01395	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MKMNKICO_01396	8.71e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MKMNKICO_01397	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MKMNKICO_01398	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MKMNKICO_01399	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MKMNKICO_01400	1.37e-271	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MKMNKICO_01401	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MKMNKICO_01402	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKMNKICO_01403	4.45e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKMNKICO_01404	3.43e-118	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MKMNKICO_01405	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKMNKICO_01406	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MKMNKICO_01407	2.1e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKMNKICO_01408	2.05e-146	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MKMNKICO_01409	1.77e-261	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKMNKICO_01410	2.96e-72	ypuD	-	-	-	-	-	-	-
MKMNKICO_01411	4.99e-127	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKMNKICO_01412	7.41e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
MKMNKICO_01413	1.61e-16	-	-	-	S	-	-	-	SNARE associated Golgi protein
MKMNKICO_01415	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKMNKICO_01416	2.67e-193	ypuA	-	-	S	-	-	-	Secreted protein
MKMNKICO_01417	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKMNKICO_01418	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MKMNKICO_01419	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MKMNKICO_01420	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MKMNKICO_01421	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MKMNKICO_01422	5.52e-101	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MKMNKICO_01423	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
MKMNKICO_01424	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MKMNKICO_01425	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKMNKICO_01426	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MKMNKICO_01427	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MKMNKICO_01428	2.89e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MKMNKICO_01429	8.04e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MKMNKICO_01430	2.77e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MKMNKICO_01431	1.59e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MKMNKICO_01432	2.25e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MKMNKICO_01433	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MKMNKICO_01434	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MKMNKICO_01435	3.73e-44	yqkK	-	-	-	-	-	-	-
MKMNKICO_01436	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MKMNKICO_01437	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MKMNKICO_01438	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MKMNKICO_01439	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MKMNKICO_01440	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_01441	2.62e-283	yqxK	-	-	L	-	-	-	DNA helicase
MKMNKICO_01442	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MKMNKICO_01443	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MKMNKICO_01444	2.65e-217	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MKMNKICO_01445	1.78e-29	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MKMNKICO_01446	7.12e-226	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MKMNKICO_01447	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MKMNKICO_01448	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MKMNKICO_01449	3.37e-250	yqkA	-	-	K	-	-	-	GrpB protein
MKMNKICO_01450	2.25e-71	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MKMNKICO_01451	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MKMNKICO_01452	9.27e-66	yqiX	-	-	S	-	-	-	YolD-like protein
MKMNKICO_01453	4.7e-303	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKMNKICO_01455	7.01e-286	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
MKMNKICO_01457	1.28e-93	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKMNKICO_01458	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MKMNKICO_01459	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MKMNKICO_01460	3.41e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_01461	1.09e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MKMNKICO_01462	2.56e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKMNKICO_01463	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MKMNKICO_01464	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MKMNKICO_01465	1.29e-186	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MKMNKICO_01466	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MKMNKICO_01467	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MKMNKICO_01468	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKMNKICO_01469	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKMNKICO_01470	2.72e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKMNKICO_01471	1.77e-32	yqzJ	-	-	-	-	-	-	-
MKMNKICO_01472	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKMNKICO_01473	2.52e-183	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
MKMNKICO_01474	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MKMNKICO_01475	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKMNKICO_01476	7.17e-99	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MKMNKICO_01478	2.41e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_01479	1.55e-224	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MKMNKICO_01480	1.28e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKMNKICO_01481	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MKMNKICO_01482	6.81e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MKMNKICO_01483	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MKMNKICO_01484	4.06e-212	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKMNKICO_01485	3.09e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_01486	6.38e-195	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
MKMNKICO_01487	3.77e-288	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKMNKICO_01488	1.98e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKMNKICO_01489	1.92e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKMNKICO_01490	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKMNKICO_01491	3.39e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MKMNKICO_01492	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKMNKICO_01493	1.18e-196	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MKMNKICO_01494	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MKMNKICO_01495	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MKMNKICO_01496	7.23e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MKMNKICO_01497	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MKMNKICO_01498	3.9e-266	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MKMNKICO_01499	2.01e-267	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MKMNKICO_01500	1.19e-199	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MKMNKICO_01501	2.59e-277	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MKMNKICO_01502	7.42e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MKMNKICO_01503	1.14e-138	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MKMNKICO_01504	4.74e-37	-	-	-	-	-	-	-	-
MKMNKICO_01505	2.81e-273	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MKMNKICO_01507	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MKMNKICO_01508	1.26e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MKMNKICO_01509	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MKMNKICO_01510	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MKMNKICO_01511	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MKMNKICO_01512	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKMNKICO_01513	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MKMNKICO_01514	3.81e-50	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKMNKICO_01515	2.05e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKMNKICO_01516	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKMNKICO_01517	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKMNKICO_01518	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_01519	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MKMNKICO_01520	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKMNKICO_01521	4.04e-134	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MKMNKICO_01522	2.43e-145	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MKMNKICO_01523	2.58e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MKMNKICO_01524	1.8e-255	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MKMNKICO_01525	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MKMNKICO_01526	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MKMNKICO_01527	5.69e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MKMNKICO_01528	3.35e-216	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MKMNKICO_01529	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MKMNKICO_01530	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKMNKICO_01531	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MKMNKICO_01532	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MKMNKICO_01533	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MKMNKICO_01534	6.02e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MKMNKICO_01535	5.18e-81	yqhP	-	-	-	-	-	-	-
MKMNKICO_01536	3.33e-208	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MKMNKICO_01537	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MKMNKICO_01538	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MKMNKICO_01539	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MKMNKICO_01540	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKMNKICO_01541	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKMNKICO_01542	1.11e-260	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MKMNKICO_01543	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKMNKICO_01544	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MKMNKICO_01545	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MKMNKICO_01546	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MKMNKICO_01547	9e-182	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MKMNKICO_01548	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MKMNKICO_01549	8e-156	yqxM	-	-	-	ko:K19433	-	ko00000	-
MKMNKICO_01550	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MKMNKICO_01551	3.33e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
MKMNKICO_01552	3.24e-58	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MKMNKICO_01553	2.77e-44	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MKMNKICO_01554	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MKMNKICO_01555	1.05e-88	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
MKMNKICO_01556	3.09e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MKMNKICO_01557	2.14e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MKMNKICO_01558	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKMNKICO_01560	3.8e-06	-	-	-	S	-	-	-	Domain in cystathionine beta-synthase and other proteins.
MKMNKICO_01561	1.51e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MKMNKICO_01562	2.86e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKMNKICO_01563	7.14e-192	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKMNKICO_01565	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MKMNKICO_01566	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MKMNKICO_01567	3.2e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MKMNKICO_01568	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MKMNKICO_01569	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
MKMNKICO_01570	2.69e-256	yqgU	-	-	-	-	-	-	-
MKMNKICO_01571	3.04e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MKMNKICO_01572	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MKMNKICO_01573	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MKMNKICO_01574	2.19e-44	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
MKMNKICO_01575	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
MKMNKICO_01576	3.38e-14	yqgO	-	-	-	-	-	-	-
MKMNKICO_01577	3.8e-135	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKMNKICO_01578	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MKMNKICO_01579	2.81e-257	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
MKMNKICO_01581	2.81e-67	yqzD	-	-	-	-	-	-	-
MKMNKICO_01582	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
MKMNKICO_01583	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKMNKICO_01584	2.4e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKMNKICO_01585	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MKMNKICO_01586	1.43e-202	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MKMNKICO_01587	2.61e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MKMNKICO_01588	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MKMNKICO_01589	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MKMNKICO_01590	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MKMNKICO_01591	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MKMNKICO_01592	1.58e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MKMNKICO_01593	1.64e-62	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MKMNKICO_01594	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MKMNKICO_01595	2.04e-81	yqfX	-	-	S	-	-	-	membrane
MKMNKICO_01596	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MKMNKICO_01597	2.47e-106	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MKMNKICO_01598	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKMNKICO_01599	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MKMNKICO_01600	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MKMNKICO_01601	5.42e-311	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MKMNKICO_01602	4.89e-58	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MKMNKICO_01603	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MKMNKICO_01604	9.26e-270	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKMNKICO_01605	2.41e-150	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MKMNKICO_01606	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MKMNKICO_01607	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKMNKICO_01608	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKMNKICO_01609	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MKMNKICO_01610	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MKMNKICO_01611	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
MKMNKICO_01612	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MKMNKICO_01613	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MKMNKICO_01614	5.26e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MKMNKICO_01615	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
MKMNKICO_01616	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKMNKICO_01617	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MKMNKICO_01618	1.42e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MKMNKICO_01619	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKMNKICO_01620	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MKMNKICO_01622	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MKMNKICO_01623	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MKMNKICO_01624	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MKMNKICO_01625	3.13e-79	yqfB	-	-	-	-	-	-	-
MKMNKICO_01626	8.78e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
MKMNKICO_01627	1.32e-290	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MKMNKICO_01628	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MKMNKICO_01629	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MKMNKICO_01630	2.04e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MKMNKICO_01631	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MKMNKICO_01632	6.85e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MKMNKICO_01633	9.34e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MKMNKICO_01634	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKMNKICO_01635	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MKMNKICO_01636	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKMNKICO_01637	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKMNKICO_01638	2.9e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MKMNKICO_01639	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKMNKICO_01640	7.06e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MKMNKICO_01641	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MKMNKICO_01642	1.39e-257	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MKMNKICO_01643	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MKMNKICO_01644	1.16e-243	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MKMNKICO_01645	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
MKMNKICO_01646	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MKMNKICO_01647	5.39e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MKMNKICO_01648	6.65e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MKMNKICO_01649	2.69e-189	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKMNKICO_01650	9.8e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
MKMNKICO_01651	9.76e-82	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKMNKICO_01652	4.81e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MKMNKICO_01653	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKMNKICO_01654	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MKMNKICO_01655	8.44e-201	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKMNKICO_01656	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MKMNKICO_01657	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MKMNKICO_01659	6.41e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MKMNKICO_01660	4.44e-172	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MKMNKICO_01661	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MKMNKICO_01662	1.29e-23	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
MKMNKICO_01663	3e-169	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
MKMNKICO_01664	9.38e-171	-	-	-	-	-	-	-	-
MKMNKICO_01665	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MKMNKICO_01666	1.1e-72	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKMNKICO_01667	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
MKMNKICO_01668	9.82e-101	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MKMNKICO_01669	7.13e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Arsenic resistance protein
MKMNKICO_01670	2.56e-104	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKMNKICO_01671	1.37e-67	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
MKMNKICO_01672	2.08e-197	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MKMNKICO_01673	1.37e-30	-	-	-	S	-	-	-	YtkA-like
MKMNKICO_01674	9e-62	-	-	-	S	-	-	-	PepSY-associated TM region
MKMNKICO_01675	1.69e-142	-	-	-	S	-	-	-	PepSY-associated TM region
MKMNKICO_01676	3.16e-81	-	-	-	K	-	-	-	BetI-type transcriptional repressor, C-terminal
MKMNKICO_01677	1.78e-175	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MKMNKICO_01678	1.41e-61	-	-	-	-	-	-	-	-
MKMNKICO_01679	1.51e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3992)
MKMNKICO_01680	4.35e-53	-	-	-	S	-	-	-	Spore coat protein Z
MKMNKICO_01681	1.14e-117	-	-	-	S	-	-	-	Tetratricopeptide repeat
MKMNKICO_01684	0.0	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
MKMNKICO_01685	1.37e-135	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
MKMNKICO_01687	5.4e-80	-	-	-	-	-	-	-	-
MKMNKICO_01689	9.72e-187	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MKMNKICO_01690	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
MKMNKICO_01691	2.45e-213	xepA	-	-	-	-	-	-	-
MKMNKICO_01692	9.34e-33	-	-	-	-	-	-	-	-
MKMNKICO_01693	1.01e-73	xkdW	-	-	S	-	-	-	XkdW protein
MKMNKICO_01694	2.91e-283	-	-	-	-	-	-	-	-
MKMNKICO_01695	3e-54	-	-	-	-	-	-	-	-
MKMNKICO_01696	4.58e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MKMNKICO_01697	1.31e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MKMNKICO_01698	1.14e-91	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MKMNKICO_01699	6.68e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MKMNKICO_01700	1.02e-231	xkdQ	-	-	G	-	-	-	NLP P60 protein
MKMNKICO_01701	6.56e-156	xkdP	-	-	S	-	-	-	Lysin motif
MKMNKICO_01702	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MKMNKICO_01703	9.14e-88	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MKMNKICO_01705	7.03e-98	xkdM	-	-	S	-	-	-	Phage tail tube protein
MKMNKICO_01706	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MKMNKICO_01707	1.21e-34	-	-	-	-	-	-	-	-
MKMNKICO_01708	1.48e-98	yqbJ	-	-	-	-	-	-	-
MKMNKICO_01709	1.79e-112	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MKMNKICO_01710	9.68e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MKMNKICO_01711	1.43e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MKMNKICO_01712	2.12e-60	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
MKMNKICO_01713	8.83e-214	xkdG	-	-	S	-	-	-	Phage capsid family
MKMNKICO_01714	4.23e-158	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
MKMNKICO_01716	1.79e-194	-	-	-	S	-	-	-	Phage Mu protein F like protein
MKMNKICO_01717	0.0	yqbA	-	-	S	-	-	-	portal protein
MKMNKICO_01718	2.69e-312	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MKMNKICO_01719	7.73e-147	yqaS	-	-	L	-	-	-	DNA packaging
MKMNKICO_01721	2.83e-99	yqaQ	-	-	L	-	-	-	Transposase
MKMNKICO_01723	8.38e-42	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
MKMNKICO_01724	1.28e-93	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MKMNKICO_01726	5.04e-207	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
MKMNKICO_01727	5.29e-156	yqaL	-	-	L	-	-	-	DnaD domain protein
MKMNKICO_01728	2.79e-192	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MKMNKICO_01729	3.18e-213	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
MKMNKICO_01733	1.04e-133	-	-	-	-	-	-	-	-
MKMNKICO_01735	3.43e-49	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKMNKICO_01736	1.25e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
MKMNKICO_01738	8.73e-132	yqaC	-	-	F	-	-	-	adenylate kinase activity
MKMNKICO_01739	1.58e-122	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MKMNKICO_01740	4.46e-79	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKMNKICO_01741	7.32e-306	yrkQ	-	-	T	-	-	-	Histidine kinase
MKMNKICO_01742	1.24e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
MKMNKICO_01743	2.16e-282	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MKMNKICO_01744	6.33e-133	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MKMNKICO_01745	5.71e-126	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
MKMNKICO_01746	3.13e-104	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
MKMNKICO_01747	1.9e-149	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MKMNKICO_01748	3.2e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
MKMNKICO_01749	2.07e-263	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
MKMNKICO_01750	2.28e-126	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
MKMNKICO_01751	7.44e-86	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
MKMNKICO_01752	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_01753	1.82e-137	yrkC	-	-	G	-	-	-	Cupin domain
MKMNKICO_01754	1.24e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKMNKICO_01755	7.59e-269	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_01756	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
MKMNKICO_01757	1.02e-297	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKMNKICO_01758	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
MKMNKICO_01759	2.84e-215	yrdR	-	-	EG	-	-	-	EamA-like transporter family
MKMNKICO_01760	1.64e-202	-	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_01761	7.41e-255	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MKMNKICO_01762	2e-211	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MKMNKICO_01763	1.44e-86	yodA	-	-	S	-	-	-	tautomerase
MKMNKICO_01764	6.6e-201	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MKMNKICO_01765	5.01e-41	-	-	-	C	-	-	-	COG2041 Sulfite oxidase and related enzymes
MKMNKICO_01766	1.43e-291	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MKMNKICO_01767	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
MKMNKICO_01768	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
MKMNKICO_01769	1.18e-103	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
MKMNKICO_01770	5.04e-22	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MKMNKICO_01771	8.91e-289	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MKMNKICO_01772	7.38e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
MKMNKICO_01773	2.99e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
MKMNKICO_01774	1.17e-117	yrdA	-	-	S	-	-	-	DinB family
MKMNKICO_01775	5.77e-210	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MKMNKICO_01776	5.15e-247	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MKMNKICO_01777	1.39e-187	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MKMNKICO_01778	4.62e-160	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MKMNKICO_01779	6.71e-128	-	-	-	K	ko:K05799	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MKMNKICO_01781	4.11e-268	-	-	-	P	-	-	-	Major Facilitator Superfamily
MKMNKICO_01782	6.21e-148	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_01783	1.02e-192	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
MKMNKICO_01784	4.98e-172	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG3959 Transketolase, N-terminal subunit
MKMNKICO_01785	3.1e-126	-	-	-	S	-	-	-	Flavin reductase like domain
MKMNKICO_01786	1.12e-156	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
MKMNKICO_01787	1.62e-63	-	-	-	S	-	-	-	YjbR
MKMNKICO_01788	7.31e-167	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MKMNKICO_01789	3.99e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKMNKICO_01790	5.96e-240	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
MKMNKICO_01791	2.16e-285	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MKMNKICO_01792	2.97e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_01793	1.71e-262	yraM	-	-	S	-	-	-	PrpF protein
MKMNKICO_01794	9.5e-201	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MKMNKICO_01795	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKMNKICO_01796	2.33e-194	-	-	-	S	-	-	-	Alpha beta hydrolase
MKMNKICO_01797	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
MKMNKICO_01798	1.69e-80	-	-	-	T	-	-	-	sh3 domain protein
MKMNKICO_01799	5.45e-86	-	-	-	E	-	-	-	Glyoxalase-like domain
MKMNKICO_01800	1.2e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
MKMNKICO_01801	7.91e-83	yraF	-	-	M	-	-	-	Spore coat protein
MKMNKICO_01802	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKMNKICO_01803	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
MKMNKICO_01804	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MKMNKICO_01805	3.7e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MKMNKICO_01806	3.95e-252	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MKMNKICO_01807	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MKMNKICO_01808	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MKMNKICO_01809	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MKMNKICO_01810	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MKMNKICO_01811	8.91e-106	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
MKMNKICO_01812	4.41e-96	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MKMNKICO_01813	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
MKMNKICO_01814	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MKMNKICO_01815	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
MKMNKICO_01816	1.98e-192	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
MKMNKICO_01817	8.2e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKMNKICO_01818	7.4e-193	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MKMNKICO_01819	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
MKMNKICO_01820	1.15e-70	oatA	-	-	I	-	-	-	Acyltransferase family
MKMNKICO_01821	1.55e-61	yrhK	-	-	S	-	-	-	YrhK-like protein
MKMNKICO_01822	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MKMNKICO_01823	9.22e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MKMNKICO_01824	7.42e-125	yrhH	-	-	Q	-	-	-	methyltransferase
MKMNKICO_01825	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MKMNKICO_01827	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MKMNKICO_01829	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MKMNKICO_01830	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MKMNKICO_01831	4.26e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MKMNKICO_01832	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
MKMNKICO_01833	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKMNKICO_01834	7.04e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MKMNKICO_01835	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKMNKICO_01836	7.23e-155	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MKMNKICO_01837	8.52e-37	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MKMNKICO_01838	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MKMNKICO_01839	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MKMNKICO_01840	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKMNKICO_01841	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MKMNKICO_01842	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MKMNKICO_01843	7.67e-223	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MKMNKICO_01844	1.4e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MKMNKICO_01845	7.19e-240	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKMNKICO_01846	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MKMNKICO_01847	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKMNKICO_01848	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MKMNKICO_01849	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKMNKICO_01850	8.81e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
MKMNKICO_01851	1.89e-169	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKMNKICO_01852	1.28e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MKMNKICO_01853	6.53e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKMNKICO_01854	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKMNKICO_01855	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MKMNKICO_01856	8.4e-42	yrzR	-	-	-	-	-	-	-
MKMNKICO_01857	3.39e-106	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_01858	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MKMNKICO_01859	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKMNKICO_01860	3.4e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MKMNKICO_01861	1.09e-271	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MKMNKICO_01862	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_01863	2.44e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MKMNKICO_01864	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MKMNKICO_01865	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MKMNKICO_01866	1.27e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MKMNKICO_01868	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MKMNKICO_01869	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKMNKICO_01870	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKMNKICO_01871	8.47e-117	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKMNKICO_01872	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MKMNKICO_01873	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MKMNKICO_01874	3.1e-112	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MKMNKICO_01875	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKMNKICO_01876	5.53e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MKMNKICO_01877	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKMNKICO_01878	5.83e-143	yrbG	-	-	S	-	-	-	membrane
MKMNKICO_01879	2.95e-96	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MKMNKICO_01880	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MKMNKICO_01881	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MKMNKICO_01882	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKMNKICO_01883	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MKMNKICO_01884	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKMNKICO_01885	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKMNKICO_01886	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MKMNKICO_01887	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
MKMNKICO_01888	2.65e-246	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MKMNKICO_01889	2.32e-152	yrzF	-	-	T	-	-	-	serine threonine protein kinase
MKMNKICO_01891	2.55e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
MKMNKICO_01892	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MKMNKICO_01893	8.63e-165	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MKMNKICO_01894	2.08e-69	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKMNKICO_01895	4.02e-216	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MKMNKICO_01896	7.94e-273	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MKMNKICO_01897	5.07e-202	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MKMNKICO_01898	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MKMNKICO_01899	3.35e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MKMNKICO_01900	5.86e-122	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MKMNKICO_01901	4.99e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MKMNKICO_01902	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MKMNKICO_01903	1.6e-307	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKMNKICO_01904	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MKMNKICO_01905	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MKMNKICO_01906	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MKMNKICO_01907	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MKMNKICO_01908	1.25e-206	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MKMNKICO_01909	1.5e-186	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MKMNKICO_01910	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MKMNKICO_01911	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MKMNKICO_01912	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MKMNKICO_01913	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MKMNKICO_01914	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MKMNKICO_01915	1.97e-161	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MKMNKICO_01916	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MKMNKICO_01917	3.08e-206	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MKMNKICO_01918	1.81e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MKMNKICO_01919	7.42e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MKMNKICO_01920	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKMNKICO_01921	1.53e-35	-	-	-	-	-	-	-	-
MKMNKICO_01922	9.73e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKMNKICO_01923	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MKMNKICO_01924	3.53e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MKMNKICO_01925	3.04e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MKMNKICO_01926	2.49e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MKMNKICO_01927	2.19e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MKMNKICO_01928	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MKMNKICO_01929	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MKMNKICO_01930	4.77e-116	ysxD	-	-	-	-	-	-	-
MKMNKICO_01931	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MKMNKICO_01932	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MKMNKICO_01933	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MKMNKICO_01934	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKMNKICO_01935	8.87e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKMNKICO_01936	2.73e-240	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MKMNKICO_01937	5.35e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKMNKICO_01938	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKMNKICO_01939	1.75e-254	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MKMNKICO_01940	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MKMNKICO_01941	3.91e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MKMNKICO_01942	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MKMNKICO_01943	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MKMNKICO_01945	1.71e-100	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MKMNKICO_01946	9.59e-48	ysnF	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_01948	2.34e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MKMNKICO_01949	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKMNKICO_01950	2.04e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MKMNKICO_01951	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MKMNKICO_01952	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MKMNKICO_01953	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKMNKICO_01954	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_01955	1.79e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MKMNKICO_01956	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MKMNKICO_01957	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MKMNKICO_01958	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MKMNKICO_01959	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MKMNKICO_01960	3.96e-275	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MKMNKICO_01961	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKMNKICO_01962	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MKMNKICO_01963	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MKMNKICO_01965	1.23e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MKMNKICO_01966	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MKMNKICO_01967	2.2e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MKMNKICO_01968	1.21e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_01969	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKMNKICO_01970	7.59e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MKMNKICO_01971	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKMNKICO_01972	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MKMNKICO_01973	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MKMNKICO_01974	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKMNKICO_01975	2.96e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKMNKICO_01976	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKMNKICO_01977	1.81e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKMNKICO_01978	2.57e-170	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKMNKICO_01979	4.37e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MKMNKICO_01980	1.92e-264	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MKMNKICO_01981	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
MKMNKICO_01982	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MKMNKICO_01983	2.94e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
MKMNKICO_01984	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MKMNKICO_01985	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MKMNKICO_01986	6.34e-192	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MKMNKICO_01987	6.77e-219	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MKMNKICO_01988	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MKMNKICO_01989	3.72e-282	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MKMNKICO_01990	1.74e-186	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MKMNKICO_01991	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MKMNKICO_01992	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MKMNKICO_01993	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MKMNKICO_01994	4.04e-241	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MKMNKICO_01995	4.35e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MKMNKICO_01996	2.29e-88	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MKMNKICO_01997	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
MKMNKICO_01998	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKMNKICO_01999	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MKMNKICO_02000	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKMNKICO_02002	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MKMNKICO_02003	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MKMNKICO_02004	1.96e-166	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MKMNKICO_02005	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_02006	1.2e-190	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MKMNKICO_02007	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKMNKICO_02008	5.98e-206	ytxC	-	-	S	-	-	-	YtxC-like family
MKMNKICO_02009	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MKMNKICO_02010	1.22e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MKMNKICO_02011	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MKMNKICO_02012	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKMNKICO_02013	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MKMNKICO_02014	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKMNKICO_02015	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_02016	1.12e-254	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MKMNKICO_02017	4.54e-205	ytbE	-	-	S	-	-	-	reductase
MKMNKICO_02018	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKMNKICO_02019	5.63e-137	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MKMNKICO_02020	3.88e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKMNKICO_02021	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKMNKICO_02022	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MKMNKICO_02023	3.27e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_02024	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MKMNKICO_02025	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MKMNKICO_02026	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MKMNKICO_02027	9.38e-95	ytwI	-	-	S	-	-	-	membrane
MKMNKICO_02028	6.42e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MKMNKICO_02029	4.68e-82	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MKMNKICO_02030	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MKMNKICO_02031	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKMNKICO_02032	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MKMNKICO_02033	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKMNKICO_02034	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MKMNKICO_02035	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MKMNKICO_02036	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MKMNKICO_02037	5.98e-111	ytrI	-	-	-	-	-	-	-
MKMNKICO_02038	1.15e-39	-	-	-	-	-	-	-	-
MKMNKICO_02039	1.02e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MKMNKICO_02040	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
MKMNKICO_02041	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MKMNKICO_02042	6.14e-204	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MKMNKICO_02043	1.41e-304	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MKMNKICO_02044	9.41e-164	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
MKMNKICO_02045	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKMNKICO_02046	1.24e-61	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
MKMNKICO_02047	6.9e-234	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKMNKICO_02048	6.61e-183	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKMNKICO_02049	2.64e-152	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKMNKICO_02050	6.75e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKMNKICO_02051	2.71e-192	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MKMNKICO_02052	2.15e-193	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MKMNKICO_02053	2.31e-127	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MKMNKICO_02054	4.99e-223	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
MKMNKICO_02055	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MKMNKICO_02056	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_02058	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MKMNKICO_02059	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MKMNKICO_02060	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MKMNKICO_02061	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKMNKICO_02062	6.26e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MKMNKICO_02063	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKMNKICO_02064	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MKMNKICO_02065	5.03e-150	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MKMNKICO_02066	2.36e-111	yteJ	-	-	S	-	-	-	RDD family
MKMNKICO_02067	5.87e-231	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MKMNKICO_02068	4.85e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKMNKICO_02069	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MKMNKICO_02070	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKMNKICO_02071	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MKMNKICO_02072	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKMNKICO_02073	1.22e-269	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MKMNKICO_02074	8.23e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MKMNKICO_02075	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKMNKICO_02076	3.73e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MKMNKICO_02077	1.2e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_02078	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MKMNKICO_02079	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MKMNKICO_02080	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKMNKICO_02082	1.85e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKMNKICO_02083	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKMNKICO_02084	2.84e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MKMNKICO_02085	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MKMNKICO_02086	2.65e-292	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MKMNKICO_02087	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MKMNKICO_02088	6.84e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MKMNKICO_02089	4.86e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MKMNKICO_02090	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MKMNKICO_02091	6.39e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MKMNKICO_02092	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MKMNKICO_02093	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKMNKICO_02094	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MKMNKICO_02095	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MKMNKICO_02096	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKMNKICO_02097	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MKMNKICO_02098	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
MKMNKICO_02099	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MKMNKICO_02100	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MKMNKICO_02101	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
MKMNKICO_02102	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MKMNKICO_02103	5.09e-192	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MKMNKICO_02104	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKMNKICO_02105	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
MKMNKICO_02106	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
MKMNKICO_02107	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MKMNKICO_02108	9.05e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MKMNKICO_02109	4.04e-211	ytlQ	-	-	-	-	-	-	-
MKMNKICO_02110	4.29e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MKMNKICO_02111	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MKMNKICO_02112	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MKMNKICO_02113	2.35e-286	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MKMNKICO_02114	3.51e-255	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MKMNKICO_02115	5.66e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MKMNKICO_02116	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MKMNKICO_02117	7.43e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MKMNKICO_02118	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKMNKICO_02119	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MKMNKICO_02120	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MKMNKICO_02121	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MKMNKICO_02122	1.55e-149	yteU	-	-	S	-	-	-	Integral membrane protein
MKMNKICO_02123	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKMNKICO_02124	4.78e-94	yteS	-	-	G	-	-	-	transport
MKMNKICO_02125	1.88e-275	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MKMNKICO_02126	2.27e-221	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MKMNKICO_02127	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_02128	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MKMNKICO_02129	1.02e-191	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MKMNKICO_02130	8.64e-176	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
MKMNKICO_02131	1.03e-284	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MKMNKICO_02132	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MKMNKICO_02133	9.36e-160	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MKMNKICO_02134	6.91e-280	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MKMNKICO_02135	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MKMNKICO_02136	2.73e-180	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MKMNKICO_02137	1.95e-220	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
MKMNKICO_02138	1.53e-242	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_02139	7.08e-310	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKMNKICO_02140	5.54e-213	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKMNKICO_02141	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MKMNKICO_02142	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MKMNKICO_02143	7.08e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
MKMNKICO_02144	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MKMNKICO_02145	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MKMNKICO_02146	5.43e-183	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MKMNKICO_02147	1.21e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MKMNKICO_02148	5.75e-78	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MKMNKICO_02149	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MKMNKICO_02150	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_02151	4.53e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MKMNKICO_02152	2.07e-166	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_02153	6.91e-297	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MKMNKICO_02154	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_02155	1.63e-163	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MKMNKICO_02156	5.22e-187	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKMNKICO_02157	1.4e-205	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_02158	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MKMNKICO_02160	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MKMNKICO_02161	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MKMNKICO_02162	1.59e-135	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MKMNKICO_02163	2.78e-275	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MKMNKICO_02164	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MKMNKICO_02165	5.88e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MKMNKICO_02166	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKMNKICO_02167	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MKMNKICO_02168	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKMNKICO_02169	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MKMNKICO_02170	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MKMNKICO_02171	5.48e-190	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MKMNKICO_02172	6.26e-239	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MKMNKICO_02173	6.12e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKMNKICO_02174	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKMNKICO_02175	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MKMNKICO_02176	6.47e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MKMNKICO_02177	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MKMNKICO_02179	6.79e-95	ytkA	-	-	S	-	-	-	YtkA-like
MKMNKICO_02180	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKMNKICO_02181	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MKMNKICO_02182	1.44e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MKMNKICO_02183	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MKMNKICO_02184	6.96e-240	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MKMNKICO_02185	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MKMNKICO_02186	2.65e-191	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MKMNKICO_02187	1.01e-293	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MKMNKICO_02188	9.74e-176	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MKMNKICO_02189	3.77e-217	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MKMNKICO_02190	2.88e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MKMNKICO_02191	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MKMNKICO_02192	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MKMNKICO_02193	1.29e-192	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MKMNKICO_02194	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MKMNKICO_02195	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MKMNKICO_02196	7.13e-168	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MKMNKICO_02197	2.82e-195	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
MKMNKICO_02198	1.6e-307	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKMNKICO_02199	1.23e-227	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
MKMNKICO_02200	5.88e-297	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
MKMNKICO_02202	2.82e-262	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
MKMNKICO_02203	1.01e-275	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
MKMNKICO_02204	1.29e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
MKMNKICO_02205	1.9e-99	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MKMNKICO_02206	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MKMNKICO_02207	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
MKMNKICO_02208	5.28e-238	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
MKMNKICO_02209	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKMNKICO_02210	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MKMNKICO_02243	6.37e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
MKMNKICO_02244	1.58e-36	-	-	-	-	-	-	-	-
MKMNKICO_02245	3.18e-169	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MKMNKICO_02246	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MKMNKICO_02247	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
MKMNKICO_02249	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MKMNKICO_02250	9.01e-179	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MKMNKICO_02251	8.45e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MKMNKICO_02252	4.82e-189	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKMNKICO_02253	2.2e-274	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MKMNKICO_02255	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKMNKICO_02256	2.79e-102	ygaO	-	-	-	-	-	-	-
MKMNKICO_02257	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_02259	1.92e-147	yhzB	-	-	S	-	-	-	B3/4 domain
MKMNKICO_02260	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MKMNKICO_02261	1.32e-223	yhbB	-	-	S	-	-	-	Putative amidase domain
MKMNKICO_02262	5.37e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKMNKICO_02263	1.38e-142	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MKMNKICO_02264	2.66e-95	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MKMNKICO_02265	4.06e-103	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MKMNKICO_02266	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MKMNKICO_02267	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MKMNKICO_02268	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MKMNKICO_02269	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MKMNKICO_02270	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MKMNKICO_02271	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
MKMNKICO_02272	3.95e-59	yhcC	-	-	-	-	-	-	-
MKMNKICO_02273	2.92e-69	-	-	-	-	-	-	-	-
MKMNKICO_02274	4.78e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_02275	3.24e-156	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_02276	4.37e-211	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_02277	1.4e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKMNKICO_02278	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MKMNKICO_02279	1.34e-195	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MKMNKICO_02280	7.08e-251	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MKMNKICO_02281	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKMNKICO_02282	1.13e-70	yhcM	-	-	-	-	-	-	-
MKMNKICO_02283	1.74e-107	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKMNKICO_02284	3.64e-223	yhcP	-	-	-	-	-	-	-
MKMNKICO_02285	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
MKMNKICO_02286	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MKMNKICO_02287	7.24e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MKMNKICO_02288	4.78e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MKMNKICO_02289	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MKMNKICO_02290	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MKMNKICO_02291	4.32e-155	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MKMNKICO_02292	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKMNKICO_02293	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKMNKICO_02294	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MKMNKICO_02295	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MKMNKICO_02296	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKMNKICO_02297	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MKMNKICO_02298	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MKMNKICO_02299	7.33e-270	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_02300	7.42e-142	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKMNKICO_02301	5.68e-117	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MKMNKICO_02302	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
MKMNKICO_02303	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MKMNKICO_02304	1.2e-268	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MKMNKICO_02305	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MKMNKICO_02306	1.51e-306	ygxB	-	-	M	-	-	-	Conserved TM helix
MKMNKICO_02307	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MKMNKICO_02308	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MKMNKICO_02309	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MKMNKICO_02310	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_02311	1.45e-258	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MKMNKICO_02312	1.58e-205	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_02313	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MKMNKICO_02314	2.48e-309	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKMNKICO_02315	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKMNKICO_02316	2.05e-99	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKMNKICO_02317	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MKMNKICO_02318	3.54e-257	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MKMNKICO_02319	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKMNKICO_02320	1.93e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
MKMNKICO_02321	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MKMNKICO_02322	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKMNKICO_02323	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MKMNKICO_02324	2.08e-283	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MKMNKICO_02325	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKMNKICO_02326	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKMNKICO_02327	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKMNKICO_02328	5.44e-174	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MKMNKICO_02329	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MKMNKICO_02330	4.51e-260	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MKMNKICO_02331	2.93e-180	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MKMNKICO_02332	5.7e-200	nodB1	-	-	G	-	-	-	deacetylase
MKMNKICO_02333	3.16e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MKMNKICO_02334	3.77e-305	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MKMNKICO_02335	3.85e-109	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
MKMNKICO_02336	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKMNKICO_02337	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKMNKICO_02338	3.31e-143	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MKMNKICO_02339	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MKMNKICO_02340	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MKMNKICO_02341	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MKMNKICO_02342	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MKMNKICO_02343	1.69e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MKMNKICO_02344	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MKMNKICO_02345	2.24e-262	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MKMNKICO_02346	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MKMNKICO_02347	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MKMNKICO_02348	7.54e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MKMNKICO_02349	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MKMNKICO_02351	1.6e-172	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MKMNKICO_02352	2.29e-36	-	-	-	S	-	-	-	YhzD-like protein
MKMNKICO_02353	1.31e-213	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_02354	5.99e-271	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MKMNKICO_02355	2.22e-299	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MKMNKICO_02356	0.0	yhaN	-	-	L	-	-	-	AAA domain
MKMNKICO_02357	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MKMNKICO_02358	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MKMNKICO_02359	2.29e-179	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKMNKICO_02360	1.4e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MKMNKICO_02361	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MKMNKICO_02362	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MKMNKICO_02363	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
MKMNKICO_02364	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MKMNKICO_02365	2.51e-260	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKMNKICO_02366	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MKMNKICO_02367	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MKMNKICO_02368	1.27e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MKMNKICO_02369	1.01e-161	ecsC	-	-	S	-	-	-	EcsC protein family
MKMNKICO_02370	1.48e-289	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MKMNKICO_02371	2.31e-313	yhfA	-	-	C	-	-	-	membrane
MKMNKICO_02372	1.23e-45	-	-	-	C	-	-	-	Rubrerythrin
MKMNKICO_02373	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MKMNKICO_02374	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MKMNKICO_02375	1.76e-257	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MKMNKICO_02376	5.66e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MKMNKICO_02377	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MKMNKICO_02378	1e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_02379	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MKMNKICO_02380	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKMNKICO_02381	1.61e-178	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
MKMNKICO_02382	2.68e-253	yhfE	-	-	G	-	-	-	peptidase M42
MKMNKICO_02383	6.22e-93	-	-	-	S	-	-	-	ASCH
MKMNKICO_02384	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKMNKICO_02385	5.93e-183	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MKMNKICO_02386	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MKMNKICO_02387	1.01e-141	yhfK	-	-	GM	-	-	-	NmrA-like family
MKMNKICO_02388	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MKMNKICO_02389	5.6e-85	yhfM	-	-	-	-	-	-	-
MKMNKICO_02390	1.37e-307	yhfN	-	-	O	-	-	-	Peptidase M48
MKMNKICO_02391	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKMNKICO_02392	1.47e-100	-	-	-	K	-	-	-	acetyltransferase
MKMNKICO_02393	8.03e-231	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MKMNKICO_02394	2.77e-223	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MKMNKICO_02395	3.93e-140	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MKMNKICO_02396	1.48e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MKMNKICO_02397	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MKMNKICO_02398	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MKMNKICO_02399	2.62e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MKMNKICO_02400	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MKMNKICO_02401	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_02402	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
MKMNKICO_02403	6.29e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MKMNKICO_02404	2.1e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKMNKICO_02405	2.04e-56	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MKMNKICO_02406	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKMNKICO_02407	9.31e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MKMNKICO_02408	2.12e-77	yhjD	-	-	-	-	-	-	-
MKMNKICO_02409	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MKMNKICO_02410	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKMNKICO_02411	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MKMNKICO_02412	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKMNKICO_02413	3.12e-273	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MKMNKICO_02414	3.98e-257	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MKMNKICO_02415	2.63e-205	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
MKMNKICO_02416	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MKMNKICO_02417	1.07e-239	yhjM	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_02418	1.02e-258	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MKMNKICO_02419	4.25e-271	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MKMNKICO_02420	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
MKMNKICO_02421	2.19e-100	yhjR	-	-	S	-	-	-	Rubrerythrin
MKMNKICO_02422	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MKMNKICO_02423	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MKMNKICO_02424	1.63e-279	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MKMNKICO_02425	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MKMNKICO_02426	7.78e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MKMNKICO_02427	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MKMNKICO_02428	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MKMNKICO_02429	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MKMNKICO_02430	1e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MKMNKICO_02431	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MKMNKICO_02432	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MKMNKICO_02433	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MKMNKICO_02434	8.94e-221	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MKMNKICO_02435	7.64e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MKMNKICO_02436	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
MKMNKICO_02437	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKMNKICO_02438	7.42e-132	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MKMNKICO_02439	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MKMNKICO_02440	1.07e-114	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
MKMNKICO_02441	1.54e-189	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MKMNKICO_02442	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
MKMNKICO_02443	4.04e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_02444	1.83e-235	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKMNKICO_02445	5.17e-249	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MKMNKICO_02446	9.94e-120	yisT	-	-	S	-	-	-	DinB family
MKMNKICO_02447	5.96e-128	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MKMNKICO_02448	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKMNKICO_02449	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MKMNKICO_02450	2.25e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MKMNKICO_02451	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MKMNKICO_02452	1.6e-294	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MKMNKICO_02453	2.15e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MKMNKICO_02454	1.34e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
MKMNKICO_02455	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
MKMNKICO_02456	6.77e-145	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKMNKICO_02457	2.14e-283	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MKMNKICO_02458	1.01e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_02459	1.4e-200	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKMNKICO_02460	5.09e-92	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MKMNKICO_02461	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MKMNKICO_02462	1.06e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MKMNKICO_02463	1.94e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MKMNKICO_02464	4.16e-122	-	-	-	-	-	-	-	-
MKMNKICO_02465	1.42e-218	-	-	-	-	-	-	-	-
MKMNKICO_02466	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MKMNKICO_02467	1.2e-76	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKMNKICO_02468	6.11e-120	-	-	-	-	-	-	-	-
MKMNKICO_02469	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
MKMNKICO_02470	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MKMNKICO_02471	9.13e-202	yitS	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_02472	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKMNKICO_02473	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MKMNKICO_02474	4.11e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MKMNKICO_02475	1.92e-08	-	-	-	-	-	-	-	-
MKMNKICO_02476	3.19e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MKMNKICO_02477	5.05e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MKMNKICO_02478	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MKMNKICO_02479	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
MKMNKICO_02480	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MKMNKICO_02481	2.04e-91	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MKMNKICO_02482	7.41e-255	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MKMNKICO_02483	7.4e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MKMNKICO_02484	5.4e-177	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MKMNKICO_02485	3.98e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MKMNKICO_02486	1.4e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MKMNKICO_02487	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MKMNKICO_02488	3.66e-226	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MKMNKICO_02489	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
MKMNKICO_02490	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MKMNKICO_02491	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MKMNKICO_02492	5.41e-134	yjaV	-	-	-	-	-	-	-
MKMNKICO_02493	6.4e-235	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MKMNKICO_02494	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MKMNKICO_02495	2.67e-38	yjzB	-	-	-	-	-	-	-
MKMNKICO_02496	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKMNKICO_02497	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKMNKICO_02498	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MKMNKICO_02499	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKMNKICO_02500	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKMNKICO_02501	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MKMNKICO_02502	3.73e-213	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKMNKICO_02503	1.03e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKMNKICO_02504	7.51e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MKMNKICO_02505	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MKMNKICO_02506	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKMNKICO_02507	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKMNKICO_02508	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKMNKICO_02509	3.92e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKMNKICO_02510	3.12e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKMNKICO_02511	9.6e-260	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKMNKICO_02512	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKMNKICO_02513	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKMNKICO_02514	7.1e-144	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MKMNKICO_02515	4.65e-149	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKMNKICO_02516	4.38e-282	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MKMNKICO_02517	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MKMNKICO_02518	2.68e-28	-	-	-	-	-	-	-	-
MKMNKICO_02520	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MKMNKICO_02521	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MKMNKICO_02522	7.22e-129	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKMNKICO_02523	4.94e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_02524	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MKMNKICO_02525	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MKMNKICO_02526	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKMNKICO_02527	9.01e-204	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MKMNKICO_02528	6.5e-162	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MKMNKICO_02529	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKMNKICO_02530	1.11e-174	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MKMNKICO_02531	2.32e-138	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MKMNKICO_02532	1.42e-271	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MKMNKICO_02533	1.8e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
MKMNKICO_02534	2.76e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MKMNKICO_02535	6.18e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MKMNKICO_02536	3.98e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MKMNKICO_02537	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MKMNKICO_02538	3.11e-98	yjbX	-	-	S	-	-	-	Spore coat protein
MKMNKICO_02539	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MKMNKICO_02540	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MKMNKICO_02541	1.23e-95	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MKMNKICO_02542	9.3e-32	cotW	-	-	-	ko:K06341	-	ko00000	-
MKMNKICO_02543	2.34e-66	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
MKMNKICO_02544	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MKMNKICO_02547	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MKMNKICO_02548	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKMNKICO_02549	6.31e-51	-	-	-	-	-	-	-	-
MKMNKICO_02550	1.1e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKMNKICO_02551	6.97e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MKMNKICO_02552	1.91e-177	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MKMNKICO_02553	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKMNKICO_02554	7.47e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKMNKICO_02555	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MKMNKICO_02556	1.05e-273	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
MKMNKICO_02558	4.53e-182	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MKMNKICO_02559	1.89e-60	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MKMNKICO_02562	3.26e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKMNKICO_02563	3e-05	-	-	-	K	-	-	-	Helix-turn-helix domain
MKMNKICO_02564	8.03e-22	-	-	-	S	-	-	-	Helix-turn-helix domain
MKMNKICO_02565	7.12e-56	-	-	-	S	-	-	-	DNA binding
MKMNKICO_02566	1.89e-88	-	-	-	-	-	-	-	-
MKMNKICO_02572	3.94e-123	-	-	-	-	-	-	-	-
MKMNKICO_02573	8.94e-88	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
MKMNKICO_02575	5.74e-97	yqaL	-	-	L	-	-	-	DnaD domain protein
MKMNKICO_02576	5.25e-103	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
MKMNKICO_02578	6.24e-95	-	-	-	-	-	-	-	-
MKMNKICO_02579	2.59e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
MKMNKICO_02581	1.85e-29	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
MKMNKICO_02583	8.96e-98	-	-	-	-	-	-	-	-
MKMNKICO_02596	1.77e-103	-	-	-	L	-	-	-	Transposase
MKMNKICO_02598	5.01e-115	yqaS	-	-	L	-	-	-	DNA packaging
MKMNKICO_02599	6.46e-273	-	-	-	S	ko:K06909	-	ko00000	Terminase RNAseH like domain
MKMNKICO_02600	2.87e-211	-	-	-	S	-	-	-	portal protein
MKMNKICO_02601	4.03e-116	-	-	-	M	-	-	-	Phage minor capsid protein 2
MKMNKICO_02602	1.28e-25	-	-	-	-	-	-	-	-
MKMNKICO_02603	1.16e-123	-	-	-	-	-	-	-	-
MKMNKICO_02604	5.32e-10	chiA	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 18 family
MKMNKICO_02605	2.32e-27	-	-	-	-	-	-	-	-
MKMNKICO_02607	2.49e-28	-	-	-	S	-	-	-	Minor capsid protein
MKMNKICO_02609	3.38e-53	-	-	-	N	-	-	-	Belongs to the glycosyl hydrolase family 6
MKMNKICO_02611	1.83e-45	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
MKMNKICO_02612	6.65e-146	-	-	-	D	-	-	-	minor tail protein
MKMNKICO_02613	2.45e-40	-	-	-	S	-	-	-	Phage tail protein
MKMNKICO_02614	4.57e-207	-	-	-	L	-	-	-	Phage minor structural protein
MKMNKICO_02619	5.36e-76	-	-	-	S	-	-	-	Bacteriophage holin family
MKMNKICO_02620	2.8e-138	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MKMNKICO_02621	1.61e-38	-	-	-	KLT	-	-	-	serine threonine protein kinase
MKMNKICO_02623	1.36e-37	-	-	-	K	-	-	-	Helix-turn-helix domain
MKMNKICO_02624	1.84e-70	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
MKMNKICO_02625	1.56e-60	-	-	-	S	-	-	-	YolD-like protein
MKMNKICO_02627	1.33e-50	-	-	-	-	-	-	-	-
MKMNKICO_02629	2.35e-295	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
MKMNKICO_02632	1.42e-09	-	-	-	S	-	-	-	YolD-like protein
MKMNKICO_02633	1.92e-47	-	-	-	-	-	-	-	-
MKMNKICO_02634	3.94e-26	-	-	-	-	-	-	-	-
MKMNKICO_02635	2.49e-07	-	-	-	-	-	-	-	-
MKMNKICO_02636	5.19e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MKMNKICO_02637	9.79e-181	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MKMNKICO_02638	0.000759	-	-	-	-	-	-	-	-
MKMNKICO_02639	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MKMNKICO_02640	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_02641	1.4e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MKMNKICO_02642	3.08e-74	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MKMNKICO_02643	5.12e-117	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKMNKICO_02645	8.3e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKMNKICO_02646	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
MKMNKICO_02647	4.66e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MKMNKICO_02648	1.52e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKMNKICO_02650	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MKMNKICO_02651	2.22e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
MKMNKICO_02652	1.95e-30	yjfB	-	-	S	-	-	-	Putative motility protein
MKMNKICO_02653	1.42e-213	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MKMNKICO_02654	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MKMNKICO_02655	1.22e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MKMNKICO_02656	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MKMNKICO_02657	6.51e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MKMNKICO_02659	3.17e-148	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MKMNKICO_02661	1.25e-281	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MKMNKICO_02662	5.89e-278	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MKMNKICO_02663	1.11e-41	-	-	-	-	-	-	-	-
MKMNKICO_02664	1.13e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MKMNKICO_02665	1.82e-155	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MKMNKICO_02666	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKMNKICO_02667	3.12e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MKMNKICO_02668	1.42e-117	yjlB	-	-	S	-	-	-	Cupin domain
MKMNKICO_02669	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MKMNKICO_02670	3.56e-279	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MKMNKICO_02671	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MKMNKICO_02672	4.34e-314	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
MKMNKICO_02673	2.08e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
MKMNKICO_02674	9.24e-246	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MKMNKICO_02675	3.92e-273	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MKMNKICO_02676	5.47e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKMNKICO_02677	9.24e-288	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
MKMNKICO_02678	9.87e-238	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MKMNKICO_02679	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MKMNKICO_02680	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MKMNKICO_02681	1.59e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MKMNKICO_02682	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
MKMNKICO_02683	1.67e-311	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
MKMNKICO_02684	3.5e-271	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKMNKICO_02686	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
MKMNKICO_02687	5.12e-216	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MKMNKICO_02688	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
MKMNKICO_02689	3.73e-137	yjqB	-	-	S	-	-	-	Pfam:DUF867
MKMNKICO_02690	4.2e-190	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
MKMNKICO_02691	1.79e-143	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MKMNKICO_02692	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKMNKICO_02694	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
MKMNKICO_02695	3.55e-151	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MKMNKICO_02699	9.88e-111	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MKMNKICO_02700	7.93e-178	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MKMNKICO_02701	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MKMNKICO_02702	0.0	yqbA	-	-	S	-	-	-	portal protein
MKMNKICO_02703	9.88e-177	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MKMNKICO_02704	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
MKMNKICO_02705	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MKMNKICO_02706	1.5e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MKMNKICO_02707	8.3e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MKMNKICO_02708	2.87e-101	xkdJ	-	-	-	-	-	-	-
MKMNKICO_02709	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MKMNKICO_02710	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
MKMNKICO_02711	9.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MKMNKICO_02712	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MKMNKICO_02713	4.25e-152	xkdP	-	-	S	-	-	-	Lysin motif
MKMNKICO_02714	1.56e-230	xkdQ	-	-	G	-	-	-	NLP P60 protein
MKMNKICO_02715	5.05e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MKMNKICO_02716	1.1e-89	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MKMNKICO_02717	1.47e-242	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MKMNKICO_02718	3.23e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MKMNKICO_02719	4.43e-56	-	-	-	-	-	-	-	-
MKMNKICO_02720	1.87e-219	-	-	-	-	-	-	-	-
MKMNKICO_02721	1.28e-59	xkdW	-	-	S	-	-	-	XkdW protein
MKMNKICO_02722	6.35e-31	xkdX	-	-	-	-	-	-	-
MKMNKICO_02723	2.21e-193	xepA	-	-	-	-	-	-	-
MKMNKICO_02724	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MKMNKICO_02725	1.15e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
MKMNKICO_02726	5.3e-208	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MKMNKICO_02728	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MKMNKICO_02729	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MKMNKICO_02730	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MKMNKICO_02731	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MKMNKICO_02732	8.98e-310	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MKMNKICO_02733	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MKMNKICO_02734	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKMNKICO_02735	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKMNKICO_02737	2.41e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKMNKICO_02738	1.16e-178	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
MKMNKICO_02739	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MKMNKICO_02740	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKMNKICO_02741	9.02e-226	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKMNKICO_02742	1.35e-236	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKMNKICO_02743	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKMNKICO_02745	4.26e-228	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MKMNKICO_02746	1.24e-259	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MKMNKICO_02747	2.56e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MKMNKICO_02748	1.77e-238	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKMNKICO_02749	9.83e-262	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MKMNKICO_02750	4.37e-206	ykgA	-	-	E	-	-	-	Amidinotransferase
MKMNKICO_02751	3.82e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MKMNKICO_02752	2.65e-289	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKMNKICO_02753	5.85e-13	-	-	-	-	-	-	-	-
MKMNKICO_02754	3.95e-167	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MKMNKICO_02755	1.57e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
MKMNKICO_02756	3.59e-128	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKMNKICO_02757	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MKMNKICO_02758	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MKMNKICO_02759	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MKMNKICO_02760	3.16e-257	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKMNKICO_02761	3.38e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKMNKICO_02763	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MKMNKICO_02764	1.42e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MKMNKICO_02765	8.15e-94	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MKMNKICO_02766	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
MKMNKICO_02767	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKMNKICO_02768	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKMNKICO_02769	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKMNKICO_02770	3.65e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MKMNKICO_02771	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_02772	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MKMNKICO_02773	2.34e-140	ykoF	-	-	S	-	-	-	YKOF-related Family
MKMNKICO_02774	3.03e-159	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_02775	3.13e-309	ykoH	-	-	T	-	-	-	Histidine kinase
MKMNKICO_02776	2.26e-144	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MKMNKICO_02777	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MKMNKICO_02778	1.45e-08	-	-	-	-	-	-	-	-
MKMNKICO_02780	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MKMNKICO_02781	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
MKMNKICO_02782	1.63e-25	-	-	-	-	-	-	-	-
MKMNKICO_02783	3.04e-36	ykoL	-	-	-	-	-	-	-
MKMNKICO_02784	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MKMNKICO_02785	6.37e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MKMNKICO_02786	1.44e-128	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MKMNKICO_02787	4.35e-198	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MKMNKICO_02788	0.0	ykoS	-	-	-	-	-	-	-
MKMNKICO_02789	5.72e-239	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKMNKICO_02790	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MKMNKICO_02791	1.25e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MKMNKICO_02792	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
MKMNKICO_02793	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
MKMNKICO_02794	1.33e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MKMNKICO_02795	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKMNKICO_02796	1.63e-212	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MKMNKICO_02797	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MKMNKICO_02798	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MKMNKICO_02799	9.33e-198	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MKMNKICO_02800	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MKMNKICO_02802	1.77e-28	ykzE	-	-	-	-	-	-	-
MKMNKICO_02803	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MKMNKICO_02804	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_02805	1.53e-112	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKMNKICO_02807	1.33e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MKMNKICO_02808	2.47e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MKMNKICO_02809	1.99e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKMNKICO_02810	2.67e-293	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MKMNKICO_02811	2.29e-293	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MKMNKICO_02812	1.77e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MKMNKICO_02813	1.84e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MKMNKICO_02814	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MKMNKICO_02815	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
MKMNKICO_02817	5.62e-93	eag	-	-	-	-	-	-	-
MKMNKICO_02818	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MKMNKICO_02819	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MKMNKICO_02820	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MKMNKICO_02821	3.23e-178	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MKMNKICO_02822	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MKMNKICO_02823	2.36e-227	ykvI	-	-	S	-	-	-	membrane
MKMNKICO_02824	2.61e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MKMNKICO_02825	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MKMNKICO_02826	2.06e-178	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MKMNKICO_02827	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MKMNKICO_02828	2.8e-81	ykvN	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_02829	9.35e-173	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKMNKICO_02830	3.66e-296	-	-	-	M	-	-	-	Glycosyl transferases group 1
MKMNKICO_02831	7.56e-48	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
MKMNKICO_02832	1.75e-204	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
MKMNKICO_02833	8.95e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MKMNKICO_02834	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_02835	2.5e-39	-	-	-	-	-	-	-	-
MKMNKICO_02836	9.09e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MKMNKICO_02837	1.12e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKMNKICO_02838	1.31e-113	stoA	-	-	CO	-	-	-	thiol-disulfide
MKMNKICO_02839	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MKMNKICO_02840	1.93e-264	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MKMNKICO_02841	6.34e-228	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_02843	6.87e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MKMNKICO_02844	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_02845	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MKMNKICO_02846	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKMNKICO_02847	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_02848	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MKMNKICO_02849	1.06e-167	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKMNKICO_02850	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKMNKICO_02851	4.02e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MKMNKICO_02852	2.97e-169	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MKMNKICO_02853	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MKMNKICO_02854	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_02855	3.44e-282	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MKMNKICO_02856	1.05e-22	-	-	-	-	-	-	-	-
MKMNKICO_02857	2.02e-215	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MKMNKICO_02858	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
MKMNKICO_02859	2.97e-304	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_02860	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_02861	2.45e-210	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MKMNKICO_02862	2.91e-179	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_02863	2.05e-297	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MKMNKICO_02864	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_02865	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MKMNKICO_02866	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MKMNKICO_02867	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
MKMNKICO_02868	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_02869	8.34e-109	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
MKMNKICO_02870	7.7e-226	ykuO	-	-	-	-	-	-	-
MKMNKICO_02871	6.2e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MKMNKICO_02872	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MKMNKICO_02873	7.66e-274	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MKMNKICO_02874	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MKMNKICO_02875	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MKMNKICO_02876	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
MKMNKICO_02877	1.47e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
MKMNKICO_02878	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
MKMNKICO_02879	2.43e-200	yknT	-	-	-	ko:K06437	-	ko00000	-
MKMNKICO_02880	3.75e-141	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MKMNKICO_02881	1.26e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MKMNKICO_02882	2.38e-310	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MKMNKICO_02883	4.89e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MKMNKICO_02884	3.83e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MKMNKICO_02885	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MKMNKICO_02886	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKMNKICO_02887	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKMNKICO_02888	5.34e-150	yknW	-	-	S	-	-	-	Yip1 domain
MKMNKICO_02889	8.16e-234	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKMNKICO_02890	1.44e-158	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_02891	1.58e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MKMNKICO_02892	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_02893	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MKMNKICO_02894	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MKMNKICO_02895	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKMNKICO_02896	5.43e-52	ykoA	-	-	-	-	-	-	-
MKMNKICO_02897	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKMNKICO_02898	2.86e-215	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKMNKICO_02899	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MKMNKICO_02900	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MKMNKICO_02901	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MKMNKICO_02902	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MKMNKICO_02903	2.65e-306	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MKMNKICO_02904	8.06e-197	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MKMNKICO_02905	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MKMNKICO_02906	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MKMNKICO_02907	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKMNKICO_02908	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MKMNKICO_02909	4.79e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MKMNKICO_02910	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKMNKICO_02911	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MKMNKICO_02912	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MKMNKICO_02913	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKMNKICO_02914	1.75e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKMNKICO_02915	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKMNKICO_02916	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKMNKICO_02917	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MKMNKICO_02918	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MKMNKICO_02919	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MKMNKICO_02920	1.45e-149	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MKMNKICO_02921	4.48e-35	ykzI	-	-	-	-	-	-	-
MKMNKICO_02922	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MKMNKICO_02923	2.98e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MKMNKICO_02924	2.88e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MKMNKICO_02925	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MKMNKICO_02926	0.0	ylaA	-	-	-	-	-	-	-
MKMNKICO_02927	1.44e-56	ylaB	-	-	-	-	-	-	-
MKMNKICO_02928	1.45e-114	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKMNKICO_02930	1.74e-57	ylaE	-	-	-	-	-	-	-
MKMNKICO_02931	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MKMNKICO_02932	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MKMNKICO_02933	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
MKMNKICO_02934	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_02935	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKMNKICO_02936	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MKMNKICO_02937	1.09e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKMNKICO_02938	3.49e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MKMNKICO_02939	5.71e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MKMNKICO_02940	2.87e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MKMNKICO_02941	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MKMNKICO_02942	1.65e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MKMNKICO_02943	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKMNKICO_02944	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MKMNKICO_02945	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKMNKICO_02946	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MKMNKICO_02947	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MKMNKICO_02948	1.04e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MKMNKICO_02949	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
MKMNKICO_02950	3.09e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MKMNKICO_02951	1.53e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MKMNKICO_02952	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
MKMNKICO_02953	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MKMNKICO_02954	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MKMNKICO_02955	8.8e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
MKMNKICO_02956	1.74e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MKMNKICO_02957	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKMNKICO_02958	5.5e-282	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MKMNKICO_02959	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MKMNKICO_02960	3.18e-238	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MKMNKICO_02961	1.05e-294	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MKMNKICO_02963	1.99e-116	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MKMNKICO_02964	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MKMNKICO_02965	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MKMNKICO_02966	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
MKMNKICO_02967	9.62e-216	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKMNKICO_02968	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MKMNKICO_02969	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MKMNKICO_02970	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKMNKICO_02971	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
MKMNKICO_02972	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MKMNKICO_02973	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MKMNKICO_02974	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKMNKICO_02975	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKMNKICO_02976	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKMNKICO_02977	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MKMNKICO_02978	4.66e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKMNKICO_02979	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MKMNKICO_02980	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MKMNKICO_02981	4.5e-142	ylxW	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_02982	1.03e-123	ylxX	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_02983	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
MKMNKICO_02984	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MKMNKICO_02985	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKMNKICO_02986	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MKMNKICO_02988	1.48e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MKMNKICO_02989	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKMNKICO_02990	1.14e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKMNKICO_02991	1.83e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MKMNKICO_02992	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MKMNKICO_02993	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
MKMNKICO_02994	7.23e-201	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MKMNKICO_02995	9.03e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKMNKICO_02996	4.47e-87	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKMNKICO_02997	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MKMNKICO_02998	3.67e-179	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MKMNKICO_02999	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MKMNKICO_03000	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKMNKICO_03001	9.18e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MKMNKICO_03002	5.47e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKMNKICO_03003	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MKMNKICO_03004	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKMNKICO_03005	3.71e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MKMNKICO_03006	1.04e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MKMNKICO_03007	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKMNKICO_03008	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MKMNKICO_03009	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MKMNKICO_03010	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MKMNKICO_03011	1.22e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKMNKICO_03012	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MKMNKICO_03013	1.27e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKMNKICO_03015	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MKMNKICO_03016	6.01e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MKMNKICO_03017	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MKMNKICO_03018	3.76e-140	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MKMNKICO_03019	5.9e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MKMNKICO_03020	1.45e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MKMNKICO_03021	1.08e-106	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MKMNKICO_03022	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MKMNKICO_03023	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MKMNKICO_03024	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
MKMNKICO_03025	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MKMNKICO_03026	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MKMNKICO_03027	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKMNKICO_03028	7.28e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKMNKICO_03029	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKMNKICO_03030	8.3e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKMNKICO_03031	1.28e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKMNKICO_03032	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKMNKICO_03033	5.3e-264	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MKMNKICO_03034	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MKMNKICO_03035	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MKMNKICO_03036	3.92e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKMNKICO_03037	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MKMNKICO_03038	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MKMNKICO_03039	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MKMNKICO_03040	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_03041	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MKMNKICO_03042	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MKMNKICO_03043	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MKMNKICO_03044	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKMNKICO_03045	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MKMNKICO_03046	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MKMNKICO_03047	1.79e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MKMNKICO_03048	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MKMNKICO_03049	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKMNKICO_03050	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKMNKICO_03051	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MKMNKICO_03052	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKMNKICO_03053	1.67e-114	-	-	-	-	-	-	-	-
MKMNKICO_03054	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKMNKICO_03055	9.7e-309	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKMNKICO_03056	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MKMNKICO_03057	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MKMNKICO_03058	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
MKMNKICO_03059	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKMNKICO_03060	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MKMNKICO_03061	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKMNKICO_03062	4.89e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKMNKICO_03063	2.89e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKMNKICO_03064	0.0	ylqG	-	-	-	-	-	-	-
MKMNKICO_03065	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MKMNKICO_03066	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MKMNKICO_03067	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MKMNKICO_03068	2.66e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MKMNKICO_03069	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKMNKICO_03070	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKMNKICO_03071	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MKMNKICO_03072	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKMNKICO_03073	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKMNKICO_03074	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MKMNKICO_03075	3.27e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MKMNKICO_03076	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MKMNKICO_03077	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MKMNKICO_03078	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MKMNKICO_03079	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKMNKICO_03080	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MKMNKICO_03081	1.22e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MKMNKICO_03082	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MKMNKICO_03083	5.08e-84	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MKMNKICO_03084	1.28e-311	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MKMNKICO_03085	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MKMNKICO_03086	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MKMNKICO_03087	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MKMNKICO_03088	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKMNKICO_03089	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MKMNKICO_03090	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MKMNKICO_03091	7.87e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MKMNKICO_03092	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MKMNKICO_03093	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MKMNKICO_03094	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MKMNKICO_03095	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKMNKICO_03096	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKMNKICO_03097	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MKMNKICO_03098	1.09e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MKMNKICO_03099	2.58e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MKMNKICO_03100	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MKMNKICO_03101	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MKMNKICO_03102	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MKMNKICO_03103	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MKMNKICO_03104	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKMNKICO_03105	6.62e-99	ylxL	-	-	-	-	-	-	-
MKMNKICO_03106	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MKMNKICO_03107	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKMNKICO_03108	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MKMNKICO_03109	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKMNKICO_03110	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKMNKICO_03111	1.36e-177	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MKMNKICO_03112	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MKMNKICO_03113	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MKMNKICO_03114	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKMNKICO_03115	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKMNKICO_03116	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MKMNKICO_03117	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MKMNKICO_03118	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MKMNKICO_03119	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MKMNKICO_03120	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKMNKICO_03121	7.83e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MKMNKICO_03122	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKMNKICO_03123	1.17e-217	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKMNKICO_03124	3.84e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MKMNKICO_03125	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKMNKICO_03126	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MKMNKICO_03127	3.98e-230	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MKMNKICO_03128	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MKMNKICO_03129	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MKMNKICO_03130	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MKMNKICO_03131	8.17e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MKMNKICO_03132	4.77e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKMNKICO_03133	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MKMNKICO_03134	9.08e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKMNKICO_03135	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKMNKICO_03136	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MKMNKICO_03137	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
MKMNKICO_03138	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MKMNKICO_03139	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_03140	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_03141	1.35e-298	albE	-	-	S	-	-	-	Peptidase M16
MKMNKICO_03142	6.8e-309	ymfH	-	-	S	-	-	-	zinc protease
MKMNKICO_03143	1.49e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MKMNKICO_03144	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MKMNKICO_03145	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MKMNKICO_03146	3.05e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MKMNKICO_03147	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKMNKICO_03148	4.33e-299	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MKMNKICO_03149	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKMNKICO_03150	2.82e-280	pbpX	-	-	V	-	-	-	Beta-lactamase
MKMNKICO_03151	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MKMNKICO_03152	5.08e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MKMNKICO_03153	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MKMNKICO_03154	7.12e-254	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MKMNKICO_03155	2.4e-277	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MKMNKICO_03156	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKMNKICO_03157	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MKMNKICO_03158	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MKMNKICO_03159	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKMNKICO_03160	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKMNKICO_03161	2.93e-92	-	-	-	S	-	-	-	Regulatory protein YrvL
MKMNKICO_03163	1.13e-126	ymcC	-	-	S	-	-	-	Membrane
MKMNKICO_03164	3.43e-140	pksA	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_03165	9.47e-166	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
MKMNKICO_03166	1.78e-206	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MKMNKICO_03168	1.64e-236	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
MKMNKICO_03169	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MKMNKICO_03170	5.46e-51	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
MKMNKICO_03171	4.36e-303	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKMNKICO_03172	9.7e-314	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MKMNKICO_03173	2.04e-183	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
MKMNKICO_03174	1.75e-173	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MKMNKICO_03175	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MKMNKICO_03176	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MKMNKICO_03177	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MKMNKICO_03178	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MKMNKICO_03179	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
MKMNKICO_03180	9.72e-295	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MKMNKICO_03181	9.39e-80	ymzB	-	-	-	-	-	-	-
MKMNKICO_03182	7.65e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MKMNKICO_03183	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MKMNKICO_03185	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
MKMNKICO_03186	8.49e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MKMNKICO_03187	6.39e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
MKMNKICO_03188	2.02e-66	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MKMNKICO_03190	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
MKMNKICO_03191	3.95e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKMNKICO_03192	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MKMNKICO_03193	1.63e-31	-	-	-	-	-	-	-	-
MKMNKICO_03194	1.2e-30	ymzA	-	-	-	-	-	-	-
MKMNKICO_03195	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MKMNKICO_03196	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKMNKICO_03197	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKMNKICO_03198	2.24e-141	-	-	-	-	-	-	-	-
MKMNKICO_03199	2e-150	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MKMNKICO_03200	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MKMNKICO_03201	2.12e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKMNKICO_03202	1.95e-309	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MKMNKICO_03203	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MKMNKICO_03204	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MKMNKICO_03205	4.61e-47	-	-	-	L	-	-	-	Arm DNA-binding domain
MKMNKICO_03206	6.66e-127	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	replicative DNA helicase
MKMNKICO_03207	3.5e-30	-	-	-	-	-	-	-	-
MKMNKICO_03210	4.9e-66	-	-	-	M	-	-	-	ArpU family transcriptional regulator
MKMNKICO_03211	1.82e-31	-	-	-	S	-	-	-	FRG
MKMNKICO_03212	1.4e-86	-	-	-	S	-	-	-	regulation of transcription, DNA-dependent
MKMNKICO_03213	4.25e-25	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MKMNKICO_03218	1.89e-63	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
MKMNKICO_03219	6.85e-103	-	-	-	L	-	-	-	phage terminase small subunit
MKMNKICO_03220	1.04e-42	-	-	-	S	-	-	-	Terminase
MKMNKICO_03223	4.18e-14	-	-	-	-	-	-	-	-
MKMNKICO_03228	4.89e-202	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MKMNKICO_03229	6.49e-269	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MKMNKICO_03230	8.45e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MKMNKICO_03231	4.94e-214	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MKMNKICO_03232	1.83e-169	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MKMNKICO_03233	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKMNKICO_03234	6.51e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKMNKICO_03235	3.39e-67	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_03236	1.88e-63	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_03237	8.95e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MKMNKICO_03238	7.76e-128	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MKMNKICO_03239	9.03e-230	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MKMNKICO_03240	2.2e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKMNKICO_03242	2.74e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MKMNKICO_03243	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MKMNKICO_03244	4.79e-160	-	-	-	-	-	-	-	-
MKMNKICO_03245	7.9e-289	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MKMNKICO_03246	7.33e-309	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MKMNKICO_03247	4.31e-157	ydhC	-	-	K	-	-	-	FCD
MKMNKICO_03248	1.02e-154	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MKMNKICO_03249	4.02e-265	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MKMNKICO_03250	6.63e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MKMNKICO_03251	9.12e-147	ydgI	-	-	C	-	-	-	nitroreductase
MKMNKICO_03252	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MKMNKICO_03253	8.04e-102	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKMNKICO_03254	2.32e-115	-	-	-	S	-	-	-	DinB family
MKMNKICO_03255	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MKMNKICO_03256	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MKMNKICO_03257	2.46e-68	yycN	-	-	K	-	-	-	Acetyltransferase
MKMNKICO_03258	1.93e-68	-	-	-	S	-	-	-	DoxX-like family
MKMNKICO_03259	4.04e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKMNKICO_03260	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MKMNKICO_03261	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MKMNKICO_03262	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MKMNKICO_03263	2.57e-159	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MKMNKICO_03264	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
MKMNKICO_03266	5.33e-39	-	-	-	-	-	-	-	-
MKMNKICO_03267	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MKMNKICO_03268	7.63e-74	ydfQ	-	-	CO	-	-	-	Thioredoxin
MKMNKICO_03269	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
MKMNKICO_03270	1.51e-235	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MKMNKICO_03271	2.83e-144	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
MKMNKICO_03272	5.22e-199	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKMNKICO_03273	1.18e-186	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MKMNKICO_03274	3.77e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MKMNKICO_03275	3.87e-13	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MKMNKICO_03276	5.32e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MKMNKICO_03277	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
MKMNKICO_03278	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKMNKICO_03279	7.24e-247	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_03281	1.12e-103	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKMNKICO_03282	5.24e-159	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MKMNKICO_03283	2.34e-148	ydfE	-	-	S	-	-	-	Flavin reductase like domain
MKMNKICO_03284	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKMNKICO_03285	9.56e-195	-	-	-	EG	-	-	-	EamA-like transporter family
MKMNKICO_03286	2.59e-187	-	-	-	J	-	-	-	GNAT acetyltransferase
MKMNKICO_03287	3.53e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKMNKICO_03288	1.05e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MKMNKICO_03289	4.73e-133	ydeS	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_03290	1.13e-256	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MKMNKICO_03291	2.36e-143	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
MKMNKICO_03292	2.92e-90	ydeP	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_03293	1.32e-193	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKMNKICO_03294	8.68e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MKMNKICO_03295	2.31e-133	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MKMNKICO_03296	3.54e-95	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MKMNKICO_03297	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKMNKICO_03298	1.49e-193	ydeK	-	-	EG	-	-	-	-transporter
MKMNKICO_03300	4.22e-111	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MKMNKICO_03301	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
MKMNKICO_03302	4.01e-92	-	-	-	S	-	-	-	SNARE associated Golgi protein
MKMNKICO_03303	2.65e-176	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
MKMNKICO_03304	5.54e-146	-	-	-	T	-	-	-	Transcriptional regulator
MKMNKICO_03305	2.79e-100	-	-	-	I	-	-	-	Ribosomal RNA adenine dimethylase
MKMNKICO_03306	2.46e-140	-	-	-	-	-	-	-	-
MKMNKICO_03307	6.99e-136	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
MKMNKICO_03308	9.2e-70	ydeH	-	-	-	-	-	-	-
MKMNKICO_03309	3.8e-277	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
MKMNKICO_03310	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKMNKICO_03311	4.94e-210	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MKMNKICO_03312	2.37e-222	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MKMNKICO_03313	2.18e-213	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKMNKICO_03314	3.56e-184	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MKMNKICO_03315	5.92e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MKMNKICO_03316	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MKMNKICO_03317	4.24e-146	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
MKMNKICO_03321	6e-53	-	-	-	-	-	-	-	-
MKMNKICO_03322	1.54e-46	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MKMNKICO_03325	7.24e-08	-	-	-	S	-	-	-	Putative amidase domain
MKMNKICO_03328	9.05e-56	-	-	-	L	-	-	-	HNH nucleases
MKMNKICO_03329	8.43e-29	-	-	-	L	ko:K07451,ko:K07452	-	ko00000,ko01000,ko02048	HNH endonuclease
MKMNKICO_03330	3.85e-24	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	LXG domain of WXG superfamily
MKMNKICO_03331	2.85e-58	-	-	-	-	-	-	-	-
MKMNKICO_03332	7.32e-92	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKMNKICO_03340	1.53e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MKMNKICO_03341	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MKMNKICO_03342	1.54e-101	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKMNKICO_03343	1.32e-106	ydcG	-	-	S	-	-	-	EVE domain
MKMNKICO_03347	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MKMNKICO_03348	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKMNKICO_03349	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MKMNKICO_03350	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MKMNKICO_03351	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MKMNKICO_03352	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MKMNKICO_03353	7.34e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MKMNKICO_03354	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MKMNKICO_03355	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MKMNKICO_03356	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MKMNKICO_03357	5.29e-284	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKMNKICO_03358	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MKMNKICO_03359	1.6e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKMNKICO_03360	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MKMNKICO_03361	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MKMNKICO_03362	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MKMNKICO_03363	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKMNKICO_03364	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKMNKICO_03365	3.58e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MKMNKICO_03366	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
MKMNKICO_03367	1.35e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKMNKICO_03369	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
MKMNKICO_03370	7.45e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MKMNKICO_03371	7.67e-69	ydbL	-	-	-	-	-	-	-
MKMNKICO_03372	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKMNKICO_03373	3.23e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_03374	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
MKMNKICO_03375	8.93e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKMNKICO_03376	1.38e-154	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MKMNKICO_03377	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MKMNKICO_03378	1.43e-250	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MKMNKICO_03379	1.06e-195	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MKMNKICO_03380	4.45e-83	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MKMNKICO_03381	7.58e-79	ydbB	-	-	G	-	-	-	Cupin domain
MKMNKICO_03382	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MKMNKICO_03383	7.14e-189	ydbA	-	-	P	-	-	-	EcsC protein family
MKMNKICO_03384	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MKMNKICO_03385	1.67e-42	ydaS	-	-	S	-	-	-	membrane
MKMNKICO_03386	3.2e-285	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MKMNKICO_03387	6.14e-53	-	-	-	-	-	-	-	-
MKMNKICO_03389	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MKMNKICO_03390	2.54e-101	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MKMNKICO_03391	0.0	ydaO	-	-	E	-	-	-	amino acid
MKMNKICO_03392	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MKMNKICO_03393	1.93e-304	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MKMNKICO_03394	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
MKMNKICO_03395	3.66e-192	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MKMNKICO_03396	1.11e-260	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MKMNKICO_03397	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKMNKICO_03398	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MKMNKICO_03399	1.09e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MKMNKICO_03400	1.31e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MKMNKICO_03401	3.04e-100	ydaG	-	-	S	-	-	-	general stress protein
MKMNKICO_03402	6.34e-132	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKMNKICO_03403	1.12e-124	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MKMNKICO_03404	1.07e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_03405	1e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
MKMNKICO_03406	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MKMNKICO_03407	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MKMNKICO_03408	8.6e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
MKMNKICO_03409	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MKMNKICO_03410	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
MKMNKICO_03412	4.18e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MKMNKICO_03413	3.8e-171	kipR	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_03414	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MKMNKICO_03415	5.04e-173	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MKMNKICO_03416	1.68e-144	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MKMNKICO_03417	7.45e-20	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MKMNKICO_03418	1.87e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MKMNKICO_03419	3.82e-181	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MKMNKICO_03420	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MKMNKICO_03422	1.89e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MKMNKICO_03423	1.71e-143	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
MKMNKICO_03424	1.78e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKMNKICO_03426	5.62e-254	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MKMNKICO_03427	8.5e-266	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MKMNKICO_03428	4.81e-94	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MKMNKICO_03429	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MKMNKICO_03430	1.34e-74	-	-	-	-	-	-	-	-
MKMNKICO_03431	1.22e-137	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MKMNKICO_03432	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MKMNKICO_03433	3.99e-134	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_03434	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_03435	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MKMNKICO_03436	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKMNKICO_03437	4.64e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKMNKICO_03438	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKMNKICO_03439	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MKMNKICO_03440	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
MKMNKICO_03441	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MKMNKICO_03442	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_03443	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MKMNKICO_03444	1.18e-96	-	-	-	V	-	-	-	Restriction endonuclease
MKMNKICO_03445	4.69e-212	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MKMNKICO_03446	2.29e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_03447	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_03448	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_03449	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MKMNKICO_03450	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MKMNKICO_03452	7.71e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MKMNKICO_03453	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MKMNKICO_03454	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_03455	2.27e-279	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MKMNKICO_03456	2.05e-156	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKMNKICO_03457	2.29e-254	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MKMNKICO_03458	8.35e-297	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MKMNKICO_03459	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MKMNKICO_03461	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MKMNKICO_03462	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MKMNKICO_03463	2.15e-199	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
MKMNKICO_03464	2.82e-105	yclD	-	-	-	-	-	-	-
MKMNKICO_03465	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MKMNKICO_03466	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MKMNKICO_03467	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MKMNKICO_03468	5.32e-209	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MKMNKICO_03469	2.49e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MKMNKICO_03470	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MKMNKICO_03471	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKMNKICO_03472	8.71e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MKMNKICO_03473	2.02e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MKMNKICO_03474	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
MKMNKICO_03475	7.69e-204	ycxC	-	-	EG	-	-	-	EamA-like transporter family
MKMNKICO_03476	2.87e-120	-	-	-	S	-	-	-	YcxB-like protein
MKMNKICO_03477	6.53e-290	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKMNKICO_03478	2.71e-178	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MKMNKICO_03479	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MKMNKICO_03480	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKMNKICO_03481	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKMNKICO_03482	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
MKMNKICO_03483	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MKMNKICO_03484	1.13e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MKMNKICO_03485	1.86e-268	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKMNKICO_03486	3.23e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MKMNKICO_03487	4.78e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MKMNKICO_03488	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKMNKICO_03489	1.01e-68	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MKMNKICO_03490	1.29e-95	yckC	-	-	S	-	-	-	membrane
MKMNKICO_03493	7.26e-185	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MKMNKICO_03494	9.69e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MKMNKICO_03495	3.76e-288	yciC	-	-	S	-	-	-	GTPases (G3E family)
MKMNKICO_03496	1.04e-140	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MKMNKICO_03497	1.08e-215	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
MKMNKICO_03498	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MKMNKICO_03499	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
MKMNKICO_03500	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKMNKICO_03501	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKMNKICO_03502	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MKMNKICO_03503	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MKMNKICO_03504	1.48e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MKMNKICO_03505	2.32e-200	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
MKMNKICO_03506	2.41e-184	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
MKMNKICO_03507	7.72e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
MKMNKICO_03508	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MKMNKICO_03509	2.64e-316	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKMNKICO_03510	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MKMNKICO_03511	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MKMNKICO_03512	1.75e-183	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MKMNKICO_03513	3.16e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MKMNKICO_03514	5.4e-226	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
MKMNKICO_03515	1.02e-183	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MKMNKICO_03516	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MKMNKICO_03518	2.39e-22	tmrB	-	-	S	-	-	-	AAA domain
MKMNKICO_03519	1.43e-53	tmrB	-	-	S	-	-	-	AAA domain
MKMNKICO_03520	5.24e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MKMNKICO_03521	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MKMNKICO_03522	9.32e-317	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKMNKICO_03523	2.07e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MKMNKICO_03524	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MKMNKICO_03525	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKMNKICO_03526	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MKMNKICO_03527	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MKMNKICO_03528	9.79e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MKMNKICO_03529	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MKMNKICO_03530	2.72e-105	ycgB	-	-	-	-	-	-	-
MKMNKICO_03531	0.0	ycgA	-	-	S	-	-	-	Membrane
MKMNKICO_03532	1.97e-276	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MKMNKICO_03533	1.16e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MKMNKICO_03534	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MKMNKICO_03535	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MKMNKICO_03536	1.97e-60	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MKMNKICO_03537	1.3e-264	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MKMNKICO_03538	1.5e-275	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MKMNKICO_03539	6.97e-244	yceH	-	-	P	-	-	-	Belongs to the TelA family
MKMNKICO_03540	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MKMNKICO_03541	1.37e-174	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MKMNKICO_03542	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MKMNKICO_03543	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MKMNKICO_03544	2.17e-140	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MKMNKICO_03545	5.95e-238	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKMNKICO_03546	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MKMNKICO_03547	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MKMNKICO_03548	2.27e-220	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MKMNKICO_03549	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MKMNKICO_03550	1.96e-179	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MKMNKICO_03551	2.86e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MKMNKICO_03552	2.65e-123	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MKMNKICO_03553	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKMNKICO_03554	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKMNKICO_03555	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MKMNKICO_03556	6.81e-222	yccK	-	-	C	-	-	-	Aldo keto reductase
MKMNKICO_03557	5.64e-257	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKMNKICO_03558	2.2e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MKMNKICO_03559	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MKMNKICO_03560	1.77e-212	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MKMNKICO_03561	1.01e-254	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MKMNKICO_03562	4.32e-78	-	-	-	S	-	-	-	RDD family
MKMNKICO_03563	1.63e-146	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKMNKICO_03564	1.97e-256	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MKMNKICO_03565	1.88e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MKMNKICO_03566	2.51e-302	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MKMNKICO_03567	4.86e-259	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MKMNKICO_03568	9.85e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKMNKICO_03569	3.09e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKMNKICO_03570	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MKMNKICO_03571	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MKMNKICO_03572	5.44e-174	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
MKMNKICO_03573	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MKMNKICO_03574	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MKMNKICO_03575	2.87e-148	-	-	-	S	-	-	-	ABC-2 family transporter protein
MKMNKICO_03576	1.66e-216	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_03577	6.21e-214	ycbM	-	-	T	-	-	-	Histidine kinase
MKMNKICO_03578	3.71e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKMNKICO_03579	7.31e-218	eamA1	-	-	EG	-	-	-	spore germination
MKMNKICO_03580	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MKMNKICO_03581	2.47e-222	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
MKMNKICO_03582	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MKMNKICO_03583	4.63e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MKMNKICO_03584	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MKMNKICO_03585	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_03586	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKMNKICO_03587	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
MKMNKICO_03588	1.72e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MKMNKICO_03589	3.55e-294	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_03590	9.16e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MKMNKICO_03591	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MKMNKICO_03592	5.26e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MKMNKICO_03593	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MKMNKICO_03594	2.82e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MKMNKICO_03596	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MKMNKICO_03597	2.59e-175	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKMNKICO_03598	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_03599	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKMNKICO_03600	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MKMNKICO_03601	1.58e-59	ybfN	-	-	-	-	-	-	-
MKMNKICO_03602	4.33e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MKMNKICO_03603	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MKMNKICO_03604	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKMNKICO_03605	2.02e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MKMNKICO_03607	5.04e-230	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MKMNKICO_03608	5.85e-274	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MKMNKICO_03609	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
MKMNKICO_03610	5.27e-208	ybfH	-	-	EG	-	-	-	EamA-like transporter family
MKMNKICO_03611	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MKMNKICO_03613	2.75e-286	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_03614	2.1e-218	ybfA	-	-	K	-	-	-	FR47-like protein
MKMNKICO_03615	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MKMNKICO_03616	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MKMNKICO_03617	2.85e-210	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MKMNKICO_03618	0.0	ybeC	-	-	E	-	-	-	amino acid
MKMNKICO_03619	1.11e-54	ybyB	-	-	-	-	-	-	-
MKMNKICO_03620	3.64e-312	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MKMNKICO_03621	1.06e-192	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
MKMNKICO_03622	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
MKMNKICO_03623	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MKMNKICO_03624	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKMNKICO_03625	1.22e-271	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
MKMNKICO_03626	7.4e-193	ybdN	-	-	-	-	-	-	-
MKMNKICO_03627	3.26e-177	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MKMNKICO_03629	1.61e-218	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
MKMNKICO_03630	3.28e-156	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
MKMNKICO_03631	2.31e-232	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MKMNKICO_03632	6.47e-176	abcA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MKMNKICO_03634	6.48e-50	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C family protein
MKMNKICO_03635	7.04e-139	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
MKMNKICO_03636	1.21e-21	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKMNKICO_03638	1.81e-255	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MKMNKICO_03639	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
MKMNKICO_03641	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MKMNKICO_03642	1.6e-63	-	-	-	-	-	-	-	-
MKMNKICO_03643	1.83e-118	ybcF	-	-	P	-	-	-	carbonic anhydrase
MKMNKICO_03644	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
MKMNKICO_03645	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MKMNKICO_03646	1.06e-128	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKMNKICO_03647	1.71e-152	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MKMNKICO_03648	5.38e-220	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKMNKICO_03649	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKMNKICO_03650	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKMNKICO_03651	3.41e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_03652	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKMNKICO_03653	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MKMNKICO_03654	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKMNKICO_03660	4.19e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MKMNKICO_03661	1.81e-113	ybbJ	-	-	J	-	-	-	acetyltransferase
MKMNKICO_03662	1.11e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKMNKICO_03663	3.01e-191	ybbH	-	-	K	-	-	-	transcriptional
MKMNKICO_03664	1.04e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_03665	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MKMNKICO_03666	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MKMNKICO_03667	8.14e-303	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_03668	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MKMNKICO_03669	1.26e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MKMNKICO_03670	1.17e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_03671	2.37e-226	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_03672	5.87e-177	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MKMNKICO_03673	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
MKMNKICO_03675	2.61e-316	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MKMNKICO_03676	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MKMNKICO_03677	3.95e-72	ygzB	-	-	S	-	-	-	UPF0295 protein
MKMNKICO_03678	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MKMNKICO_03679	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MKMNKICO_03680	1.33e-311	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MKMNKICO_03681	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
MKMNKICO_03682	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MKMNKICO_03683	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MKMNKICO_03684	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MKMNKICO_03685	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MKMNKICO_03686	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKMNKICO_03687	1.73e-48	yfhS	-	-	-	-	-	-	-
MKMNKICO_03688	1.2e-267	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MKMNKICO_03689	7.22e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MKMNKICO_03690	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MKMNKICO_03691	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKMNKICO_03692	3.93e-218	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
MKMNKICO_03693	4.74e-62	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MKMNKICO_03694	1.7e-117	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MKMNKICO_03695	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
MKMNKICO_03696	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
MKMNKICO_03697	3.47e-268	yfhI	-	-	EGP	-	-	-	-transporter
MKMNKICO_03698	4.8e-67	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MKMNKICO_03699	9.32e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MKMNKICO_03700	3.11e-219	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MKMNKICO_03702	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
MKMNKICO_03703	2.87e-138	yfhC	-	-	C	-	-	-	nitroreductase
MKMNKICO_03704	7.61e-215	yfhB	-	-	S	-	-	-	PhzF family
MKMNKICO_03705	7.36e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_03706	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_03707	1.56e-230	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKMNKICO_03708	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKMNKICO_03709	2.11e-103	yfiV	-	-	K	-	-	-	transcriptional
MKMNKICO_03710	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MKMNKICO_03711	9.81e-129	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MKMNKICO_03712	8.95e-251	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MKMNKICO_03713	3.2e-127	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKMNKICO_03714	1.89e-128	padR	-	-	K	-	-	-	transcriptional
MKMNKICO_03715	3.84e-259	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MKMNKICO_03716	1.46e-264	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MKMNKICO_03717	7.89e-217	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKMNKICO_03718	6.07e-146	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MKMNKICO_03719	1.98e-271	baeS	-	-	T	-	-	-	Histidine kinase
MKMNKICO_03721	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MKMNKICO_03722	3.34e-83	yfiD3	-	-	S	-	-	-	DoxX
MKMNKICO_03723	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKMNKICO_03724	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MKMNKICO_03725	1.45e-39	-	-	-	M	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
MKMNKICO_03726	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
MKMNKICO_03727	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_03728	2.05e-179	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MKMNKICO_03729	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKMNKICO_03730	1.6e-60	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
MKMNKICO_03731	6.91e-241	yfjB	-	-	-	-	-	-	-
MKMNKICO_03732	3.83e-161	yfjC	-	-	-	-	-	-	-
MKMNKICO_03733	1.9e-109	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
MKMNKICO_03734	7.42e-75	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
MKMNKICO_03735	2.75e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MKMNKICO_03736	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MKMNKICO_03737	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKMNKICO_03738	2.7e-261	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKMNKICO_03739	2.64e-242	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKMNKICO_03740	9.2e-243	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKMNKICO_03741	9.55e-111	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MKMNKICO_03742	3.47e-243	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKMNKICO_03743	3.04e-59	-	-	-	S	-	-	-	YfzA-like protein
MKMNKICO_03744	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKMNKICO_03745	2.76e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKMNKICO_03746	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MKMNKICO_03747	5.16e-189	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MKMNKICO_03748	4.19e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MKMNKICO_03749	3.26e-36	yfjT	-	-	-	-	-	-	-
MKMNKICO_03750	7.17e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
MKMNKICO_03751	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MKMNKICO_03752	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
MKMNKICO_03753	5.44e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MKMNKICO_03754	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_03755	1.64e-12	-	-	-	-	-	-	-	-
MKMNKICO_03756	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MKMNKICO_03757	2.53e-67	yfkI	-	-	S	-	-	-	gas vesicle protein
MKMNKICO_03758	2.14e-110	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKMNKICO_03759	7.27e-42	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MKMNKICO_03760	6.21e-266	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_03761	8.44e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MKMNKICO_03762	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MKMNKICO_03763	5.27e-161	frp	-	-	C	-	-	-	nitroreductase
MKMNKICO_03764	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MKMNKICO_03765	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MKMNKICO_03766	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKMNKICO_03767	0.0	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MKMNKICO_03768	9.28e-271	yfkR	-	-	S	ko:K06297,ko:K06308	-	ko00000	spore germination
MKMNKICO_03770	2.19e-249	yfkT	-	-	E	ko:K06309	-	ko00000	Spore germination protein
MKMNKICO_03771	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MKMNKICO_03772	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MKMNKICO_03773	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MKMNKICO_03774	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MKMNKICO_03775	6.62e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MKMNKICO_03776	2.1e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MKMNKICO_03777	9.81e-27	yflI	-	-	-	-	-	-	-
MKMNKICO_03778	1.1e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MKMNKICO_03779	5.91e-158	yflK	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_03780	2.54e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MKMNKICO_03781	1.37e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MKMNKICO_03782	2.94e-193	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MKMNKICO_03783	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MKMNKICO_03784	1.45e-232	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MKMNKICO_03785	3.96e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MKMNKICO_03786	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MKMNKICO_03787	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MKMNKICO_03788	4.06e-306	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MKMNKICO_03789	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MKMNKICO_03790	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
MKMNKICO_03791	2.76e-219	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MKMNKICO_03792	8.17e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_03793	4.94e-222	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKMNKICO_03794	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MKMNKICO_03795	0.0	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
MKMNKICO_03796	1.72e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
MKMNKICO_03797	6.98e-241	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
MKMNKICO_03798	2.55e-105	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
MKMNKICO_03799	1.2e-262	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MKMNKICO_03800	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKMNKICO_03801	7.24e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MKMNKICO_03802	3.03e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MKMNKICO_03803	6.48e-99	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MKMNKICO_03804	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKMNKICO_03805	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
MKMNKICO_03806	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKMNKICO_03807	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MKMNKICO_03808	9.43e-171	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MKMNKICO_03809	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKMNKICO_03810	2.84e-244	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MKMNKICO_03811	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MKMNKICO_03812	3.99e-231	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MKMNKICO_03813	1.37e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MKMNKICO_03814	2.41e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MKMNKICO_03815	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MKMNKICO_03816	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MKMNKICO_03817	4.11e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MKMNKICO_03818	2.57e-171	-	-	-	M	-	-	-	Membrane
MKMNKICO_03819	1.78e-265	yetM	-	-	CH	-	-	-	FAD binding domain
MKMNKICO_03820	2.75e-116	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKMNKICO_03821	2.1e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MKMNKICO_03822	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MKMNKICO_03823	3.08e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKMNKICO_03824	9.79e-45	-	-	-	-	-	-	-	-
MKMNKICO_03825	7.08e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKMNKICO_03826	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MKMNKICO_03827	1.49e-156	yetF	-	-	S	-	-	-	membrane
MKMNKICO_03828	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MKMNKICO_03829	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKMNKICO_03830	6.84e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MKMNKICO_03831	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKMNKICO_03832	0.0	yetA	-	-	-	-	-	-	-
MKMNKICO_03833	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
MKMNKICO_03834	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MKMNKICO_03835	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MKMNKICO_03836	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MKMNKICO_03837	7.78e-143	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MKMNKICO_03838	7.22e-163	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
MKMNKICO_03839	9.8e-169	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MKMNKICO_03840	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_03841	5.63e-254	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
MKMNKICO_03842	5.11e-210	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKMNKICO_03843	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKMNKICO_03844	6.85e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKMNKICO_03845	1.89e-255	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MKMNKICO_03846	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKMNKICO_03847	1.95e-132	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
MKMNKICO_03848	2.4e-130	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MKMNKICO_03849	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MKMNKICO_03850	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MKMNKICO_03851	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MKMNKICO_03852	1.23e-195	yesF	-	-	GM	-	-	-	NAD(P)H-binding
MKMNKICO_03853	2.02e-106	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
MKMNKICO_03854	2.85e-129	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
MKMNKICO_03856	1.09e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MKMNKICO_03858	1.42e-270	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
MKMNKICO_03859	2.32e-235	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
MKMNKICO_03860	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
MKMNKICO_03861	1.09e-73	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MKMNKICO_03862	8.48e-105	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MKMNKICO_03864	4.5e-41	-	-	-	S	-	-	-	Colicin immunity protein / pyocin immunity protein
MKMNKICO_03866	3.95e-125	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKMNKICO_03869	6.7e-95	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MKMNKICO_03870	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system methyltransferase subunit()
MKMNKICO_03871	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKMNKICO_03872	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKMNKICO_03873	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKMNKICO_03874	2.08e-190	yerO	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_03875	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKMNKICO_03876	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKMNKICO_03877	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKMNKICO_03878	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKMNKICO_03879	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MKMNKICO_03880	2.45e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MKMNKICO_03881	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MKMNKICO_03882	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKMNKICO_03883	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MKMNKICO_03884	7.43e-160	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MKMNKICO_03886	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MKMNKICO_03887	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_03888	9.18e-242	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MKMNKICO_03889	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MKMNKICO_03890	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
MKMNKICO_03891	4.8e-291	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
MKMNKICO_03892	1.29e-94	-	-	-	K	-	-	-	helix_turn_helix ASNC type
MKMNKICO_03893	5.69e-298	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MKMNKICO_03894	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MKMNKICO_03895	8.88e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKMNKICO_03896	1.71e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MKMNKICO_03897	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKMNKICO_03898	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKMNKICO_03899	6.66e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKMNKICO_03900	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKMNKICO_03901	7.13e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MKMNKICO_03902	1.98e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKMNKICO_03903	1.05e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKMNKICO_03904	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKMNKICO_03905	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
MKMNKICO_03906	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
MKMNKICO_03908	2.78e-163	yebC	-	-	M	-	-	-	Membrane
MKMNKICO_03909	2.81e-282	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MKMNKICO_03910	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MKMNKICO_03911	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MKMNKICO_03912	1.59e-285	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MKMNKICO_03913	2.79e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MKMNKICO_03914	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKMNKICO_03915	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MKMNKICO_03916	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MKMNKICO_03917	1.9e-233	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
MKMNKICO_03918	3.21e-205	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MKMNKICO_03919	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MKMNKICO_03921	1.27e-204	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MKMNKICO_03922	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
MKMNKICO_03923	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MKMNKICO_03924	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKMNKICO_03925	1.37e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
MKMNKICO_03926	1.79e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MKMNKICO_03927	3.96e-177	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MKMNKICO_03928	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKMNKICO_03929	1.08e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MKMNKICO_03930	7.03e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MKMNKICO_03931	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MKMNKICO_03932	4.32e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MKMNKICO_03933	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MKMNKICO_03934	8.95e-31	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MKMNKICO_03935	4.31e-82	yozB	-	-	S	ko:K08976	-	ko00000	Membrane
MKMNKICO_03938	7.05e-293	-	-	-	S	-	-	-	Bacterial EndoU nuclease
MKMNKICO_03939	1.93e-53	-	-	-	-	-	-	-	-
MKMNKICO_03941	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKMNKICO_03942	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKMNKICO_03943	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MKMNKICO_03944	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MKMNKICO_03945	8.73e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKMNKICO_03946	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MKMNKICO_03947	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKMNKICO_03948	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MKMNKICO_03949	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MKMNKICO_03950	5.46e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKMNKICO_03951	2.34e-107	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MKMNKICO_03952	1.76e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MKMNKICO_03953	7.42e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MKMNKICO_03954	1.9e-231	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MKMNKICO_03962	3.51e-22	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MKMNKICO_03963	2.26e-118	-	-	-	M	-	-	-	Glycosyltransferase like family
MKMNKICO_03964	7.89e-154	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
MKMNKICO_03965	1.03e-240	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKMNKICO_03966	1.56e-274	-	-	-	H	-	-	-	N-terminal domain of galactosyltransferase
MKMNKICO_03968	3.38e-125	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKMNKICO_03970	3.45e-90	-	-	-	S	-	-	-	CAAX protease self-immunity
MKMNKICO_03971	2.38e-11	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MKMNKICO_03972	2.79e-30	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MKMNKICO_03973	1.1e-142	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MKMNKICO_03974	1.14e-61	ynaF	-	-	-	-	-	-	-
MKMNKICO_03976	1.76e-109	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
MKMNKICO_03977	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MKMNKICO_03978	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MKMNKICO_03979	5.85e-274	xylR	-	-	GK	-	-	-	ROK family
MKMNKICO_03980	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MKMNKICO_03981	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MKMNKICO_03982	2.06e-144	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MKMNKICO_03983	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MKMNKICO_03984	5.06e-280	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKMNKICO_03985	3.86e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
MKMNKICO_03986	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MKMNKICO_03987	7.54e-22	-	-	-	-	-	-	-	-
MKMNKICO_03990	2.75e-210	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKMNKICO_03992	4.44e-172	-	-	-	S	-	-	-	Domain of unknown function, YrpD
MKMNKICO_03995	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
MKMNKICO_03996	8.92e-96	-	-	-	-	-	-	-	-
MKMNKICO_03997	1.05e-102	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MKMNKICO_04000	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MKMNKICO_04001	1.95e-250	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
MKMNKICO_04002	5.57e-289	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MKMNKICO_04003	1.85e-198	yndG	-	-	S	-	-	-	DoxX-like family
MKMNKICO_04004	3.46e-149	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MKMNKICO_04005	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MKMNKICO_04007	3.26e-175	yndL	-	-	S	-	-	-	Replication protein
MKMNKICO_04008	1.32e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MKMNKICO_04009	4.44e-104	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MKMNKICO_04010	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKMNKICO_04011	2.44e-64	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MKMNKICO_04012	2.29e-144	yneB	-	-	L	-	-	-	resolvase
MKMNKICO_04013	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
MKMNKICO_04014	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKMNKICO_04015	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MKMNKICO_04016	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MKMNKICO_04017	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MKMNKICO_04018	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MKMNKICO_04019	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MKMNKICO_04020	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MKMNKICO_04021	3.97e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MKMNKICO_04022	5.77e-85	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MKMNKICO_04023	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MKMNKICO_04024	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MKMNKICO_04025	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MKMNKICO_04026	2.53e-118	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MKMNKICO_04027	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
MKMNKICO_04029	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MKMNKICO_04030	1.64e-94	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MKMNKICO_04031	2.32e-71	yneQ	-	-	-	-	-	-	-
MKMNKICO_04032	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MKMNKICO_04033	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKMNKICO_04034	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MKMNKICO_04035	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKMNKICO_04036	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKMNKICO_04037	1.82e-18	-	-	-	-	-	-	-	-
MKMNKICO_04038	1.06e-75	ynfC	-	-	-	-	-	-	-
MKMNKICO_04039	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MKMNKICO_04040	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
MKMNKICO_04042	9.85e-317	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
MKMNKICO_04043	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MKMNKICO_04044	4.06e-102	yngA	-	-	S	-	-	-	membrane
MKMNKICO_04045	7.53e-208	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MKMNKICO_04046	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
MKMNKICO_04047	7.39e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
MKMNKICO_04048	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKMNKICO_04049	1.42e-173	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MKMNKICO_04050	3.89e-211	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MKMNKICO_04051	1.19e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MKMNKICO_04052	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MKMNKICO_04053	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKMNKICO_04054	7.28e-266	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MKMNKICO_04055	2.97e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKMNKICO_04056	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MKMNKICO_04057	2.48e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MKMNKICO_04058	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
MKMNKICO_04059	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKMNKICO_04060	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKMNKICO_04065	2.65e-85	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
MKMNKICO_04067	3.46e-159	-	-	-	S	-	-	-	peptidoglycan catabolic process
MKMNKICO_04068	1.87e-238	-	-	-	S	-	-	-	Phage tail protein
MKMNKICO_04069	1.12e-174	-	-	-	D	-	-	-	Phage tail tape measure protein
MKMNKICO_04071	1.33e-52	-	-	-	S	-	-	-	Phage tail tube protein
MKMNKICO_04075	0.000105	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MKMNKICO_04077	1.96e-109	-	-	-	S	-	-	-	Phage capsid family
MKMNKICO_04078	4.5e-65	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
MKMNKICO_04079	1.82e-131	-	-	-	S	-	-	-	Phage portal protein
MKMNKICO_04082	8.66e-05	-	-	-	L	-	-	-	Phage terminase small Subunit
MKMNKICO_04085	4.91e-226	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKMNKICO_04087	6.23e-105	-	-	-	-	-	-	-	-
MKMNKICO_04089	2.33e-67	-	-	-	S	-	-	-	DNA ligase (ATP) activity
MKMNKICO_04090	4.22e-23	-	-	-	S	-	-	-	3D domain
MKMNKICO_04093	7.94e-94	-	-	-	L	-	-	-	integrase family
MKMNKICO_04097	1.23e-52	-	-	-	S	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphoribosyl-ATP pyrophosphohydrolase
MKMNKICO_04098	5.79e-19	-	-	-	-	-	-	-	-
MKMNKICO_04100	6.29e-43	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
MKMNKICO_04104	3.64e-62	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MKMNKICO_04107	2.72e-80	-	-	-	S	-	-	-	AAA domain
MKMNKICO_04108	0.0	-	-	-	S	-	-	-	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
MKMNKICO_04109	7.45e-130	-	-	-	S	-	-	-	Ribonucleotide reductase, small chain
MKMNKICO_04112	3.01e-52	-	-	-	-	-	-	-	-
MKMNKICO_04114	1.48e-10	-	-	-	-	-	-	-	-
MKMNKICO_04115	6.14e-12	-	-	-	-	-	-	-	-
MKMNKICO_04116	8.73e-132	-	-	-	S	-	-	-	DNA helicase activity
MKMNKICO_04117	4.79e-111	-	-	-	S	-	-	-	DNA primase activity
MKMNKICO_04119	2.39e-101	-	-	-	S	-	-	-	exonuclease activity
MKMNKICO_04120	1.77e-14	M1-624	-	-	K	-	-	-	Transcriptional regulator
MKMNKICO_04127	4.61e-60	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKMNKICO_04131	0.0	-	-	-	S	-	-	-	Bacterial DNA polymerase III alpha subunit
MKMNKICO_04135	7.95e-18	-	-	-	F	-	-	-	Guanylate kinase homologues.
MKMNKICO_04144	5.92e-17	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
MKMNKICO_04145	2.29e-228	-	-	-	S	-	-	-	DNA gyrase B
MKMNKICO_04146	6.66e-181	-	-	-	S	-	-	-	DNA gyrase/topoisomerase IV, subunit A
MKMNKICO_04147	6.82e-71	-	-	-	L	-	-	-	Domain of unknown function (DUF1738)
MKMNKICO_04155	2.3e-148	-	-	-	-	-	-	-	-
MKMNKICO_04156	7.94e-28	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
MKMNKICO_04157	6.95e-78	-	-	-	-	-	-	-	-
MKMNKICO_04159	7.45e-82	-	-	-	S	-	-	-	Immunity protein 70
MKMNKICO_04160	4.8e-242	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
MKMNKICO_04161	7.4e-122	-	-	-	S	-	-	-	Phage integrase family
MKMNKICO_04162	1.85e-24	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MKMNKICO_04163	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MKMNKICO_04164	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MKMNKICO_04165	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MKMNKICO_04166	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MKMNKICO_04167	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKMNKICO_04168	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MKMNKICO_04169	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MKMNKICO_04170	4.29e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MKMNKICO_04171	2.59e-112	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MKMNKICO_04172	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKMNKICO_04173	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MKMNKICO_04174	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MKMNKICO_04175	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKMNKICO_04176	3.52e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKMNKICO_04177	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MKMNKICO_04178	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MKMNKICO_04179	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKMNKICO_04180	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MKMNKICO_04181	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKMNKICO_04182	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKMNKICO_04183	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKMNKICO_04184	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKMNKICO_04185	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MKMNKICO_04186	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKMNKICO_04187	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKMNKICO_04188	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MKMNKICO_04189	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKMNKICO_04190	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKMNKICO_04191	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKMNKICO_04192	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKMNKICO_04193	8.68e-229	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MKMNKICO_04194	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MKMNKICO_04195	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKMNKICO_04196	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MKMNKICO_04197	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKMNKICO_04198	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKMNKICO_04199	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKMNKICO_04200	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKMNKICO_04201	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKMNKICO_04202	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKMNKICO_04203	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MKMNKICO_04204	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKMNKICO_04205	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKMNKICO_04206	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKMNKICO_04207	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKMNKICO_04208	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKMNKICO_04209	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKMNKICO_04210	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKMNKICO_04211	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKMNKICO_04212	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKMNKICO_04213	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MKMNKICO_04214	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MKMNKICO_04215	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKMNKICO_04216	1.46e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKMNKICO_04217	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MKMNKICO_04218	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKMNKICO_04219	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MKMNKICO_04220	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKMNKICO_04221	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKMNKICO_04222	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKMNKICO_04223	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MKMNKICO_04224	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKMNKICO_04225	1.28e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKMNKICO_04226	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKMNKICO_04227	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKMNKICO_04228	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKMNKICO_04229	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MKMNKICO_04230	2.14e-186	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MKMNKICO_04231	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MKMNKICO_04232	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MKMNKICO_04233	4.47e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MKMNKICO_04234	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
MKMNKICO_04235	2.42e-132	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MKMNKICO_04236	2.49e-180	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MKMNKICO_04237	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MKMNKICO_04238	3.28e-133	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MKMNKICO_04239	8.37e-259	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MKMNKICO_04240	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MKMNKICO_04241	2.82e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKMNKICO_04242	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_04243	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MKMNKICO_04244	2.42e-236	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MKMNKICO_04245	1.1e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MKMNKICO_04246	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MKMNKICO_04247	2.81e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MKMNKICO_04248	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MKMNKICO_04249	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKMNKICO_04250	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MKMNKICO_04251	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKMNKICO_04252	4.85e-183	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MKMNKICO_04253	1.18e-277	yabE	-	-	T	-	-	-	protein conserved in bacteria
MKMNKICO_04254	1.43e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKMNKICO_04255	5.04e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKMNKICO_04256	1.84e-197	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MKMNKICO_04257	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MKMNKICO_04258	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MKMNKICO_04259	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKMNKICO_04260	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MKMNKICO_04261	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MKMNKICO_04262	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MKMNKICO_04263	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKMNKICO_04264	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKMNKICO_04265	9.8e-135	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MKMNKICO_04266	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKMNKICO_04267	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MKMNKICO_04268	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKMNKICO_04269	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MKMNKICO_04270	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKMNKICO_04271	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MKMNKICO_04272	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MKMNKICO_04273	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MKMNKICO_04274	2.21e-139	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MKMNKICO_04275	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MKMNKICO_04276	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MKMNKICO_04279	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MKMNKICO_04280	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MKMNKICO_04281	1.63e-234	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MKMNKICO_04282	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKMNKICO_04283	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MKMNKICO_04284	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKMNKICO_04285	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MKMNKICO_04286	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKMNKICO_04287	2.72e-195	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MKMNKICO_04288	1.26e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MKMNKICO_04289	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKMNKICO_04290	1.72e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MKMNKICO_04291	1.54e-214	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MKMNKICO_04292	1.11e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MKMNKICO_04293	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MKMNKICO_04294	9.21e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKMNKICO_04295	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
MKMNKICO_04296	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKMNKICO_04297	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family