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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKDMHDKC_00001	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKDMHDKC_00002	1.29e-72	-	-	-	M	-	-	-	domain protein
HKDMHDKC_00003	0.0	-	-	-	M	-	-	-	domain protein
HKDMHDKC_00005	0.0	-	-	-	-	-	-	-	-
HKDMHDKC_00006	5.55e-143	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HKDMHDKC_00007	2.64e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HKDMHDKC_00008	7.35e-103	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HKDMHDKC_00009	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKDMHDKC_00010	1.55e-17	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKDMHDKC_00011	9.19e-21	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
HKDMHDKC_00012	5.79e-90	-	-	-	K	-	-	-	HxlR family
HKDMHDKC_00013	2.79e-64	-	-	-	-	-	-	-	-
HKDMHDKC_00014	1.73e-294	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
HKDMHDKC_00015	1.83e-15	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HKDMHDKC_00016	1.13e-98	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HKDMHDKC_00017	0.0	-	-	-	P	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
HKDMHDKC_00018	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKDMHDKC_00019	3.13e-55	-	-	-	S	-	-	-	Cupin domain
HKDMHDKC_00020	1.41e-242	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKDMHDKC_00021	4.45e-42	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HKDMHDKC_00022	2.4e-41	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKDMHDKC_00023	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HKDMHDKC_00024	5.26e-157	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HKDMHDKC_00025	6.96e-201	-	-	-	C	-	-	-	Aldo keto reductase
HKDMHDKC_00027	1.24e-129	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HKDMHDKC_00028	4.43e-296	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF1100)
HKDMHDKC_00029	6.65e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
HKDMHDKC_00030	8.01e-276	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HKDMHDKC_00031	2.78e-80	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HKDMHDKC_00032	2.7e-43	-	-	-	G	ko:K03292	-	ko00000	Major facilitator Superfamily
HKDMHDKC_00033	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKDMHDKC_00034	5.09e-82	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKDMHDKC_00035	4.3e-38	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HKDMHDKC_00036	9.67e-222	yobV3	-	-	K	-	-	-	WYL domain
HKDMHDKC_00037	5.89e-90	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HKDMHDKC_00038	2.06e-67	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKDMHDKC_00039	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HKDMHDKC_00040	9.51e-47	-	-	-	C	-	-	-	Heavy-metal-associated domain
HKDMHDKC_00041	1.13e-125	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HKDMHDKC_00042	1.24e-144	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HKDMHDKC_00043	2.34e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKDMHDKC_00044	7e-114	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HKDMHDKC_00045	2.69e-63	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HKDMHDKC_00046	1.4e-99	-	-	-	K	-	-	-	Transcriptional regulator
HKDMHDKC_00047	5.33e-90	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
HKDMHDKC_00048	2.95e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKDMHDKC_00049	1.46e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HKDMHDKC_00050	1.43e-312	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HKDMHDKC_00051	2.63e-43	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HKDMHDKC_00052	6.34e-135	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HKDMHDKC_00053	2.39e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKDMHDKC_00054	3.31e-18	-	-	-	C	-	-	-	Aldo/keto reductase family
HKDMHDKC_00055	6.98e-94	-	-	-	C	-	-	-	Aldo/keto reductase family
HKDMHDKC_00056	1.53e-213	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKDMHDKC_00057	2.95e-160	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HKDMHDKC_00058	1.4e-148	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HKDMHDKC_00059	5.23e-151	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKDMHDKC_00060	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKDMHDKC_00061	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKDMHDKC_00062	2.92e-231	-	-	-	K	-	-	-	Transcriptional regulator
HKDMHDKC_00063	3.5e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HKDMHDKC_00064	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKDMHDKC_00065	6.77e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKDMHDKC_00066	1.5e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HKDMHDKC_00067	6.93e-261	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HKDMHDKC_00068	2.76e-214	lysR	-	-	K	-	-	-	Transcriptional regulator
HKDMHDKC_00069	3.45e-197	-	-	-	-	-	-	-	-
HKDMHDKC_00070	1.93e-209	-	-	-	S	-	-	-	EDD domain protein, DegV family
HKDMHDKC_00071	5.72e-85	-	-	-	-	-	-	-	-
HKDMHDKC_00072	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HKDMHDKC_00073	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKDMHDKC_00074	4.62e-252	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKDMHDKC_00075	1.01e-220	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKDMHDKC_00076	9.07e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKDMHDKC_00077	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HKDMHDKC_00078	2.74e-77	-	-	-	-	-	-	-	-
HKDMHDKC_00079	7.03e-224	degV1	-	-	S	-	-	-	DegV family
HKDMHDKC_00080	5.31e-306	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKDMHDKC_00081	1.61e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HKDMHDKC_00082	1.37e-94	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKDMHDKC_00083	2.28e-137	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HKDMHDKC_00084	2.82e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKDMHDKC_00085	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HKDMHDKC_00086	6.69e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKDMHDKC_00087	2.06e-150	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HKDMHDKC_00088	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKDMHDKC_00089	5.37e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HKDMHDKC_00090	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HKDMHDKC_00091	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HKDMHDKC_00092	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKDMHDKC_00093	1.8e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HKDMHDKC_00094	1.67e-223	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HKDMHDKC_00095	2.53e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HKDMHDKC_00096	2.24e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKDMHDKC_00097	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKDMHDKC_00098	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKDMHDKC_00099	4.73e-203	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HKDMHDKC_00100	2.84e-207	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HKDMHDKC_00101	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKDMHDKC_00102	1.79e-110	-	-	-	S	-	-	-	ASCH
HKDMHDKC_00103	1.45e-173	-	-	-	F	-	-	-	Phosphorylase superfamily
HKDMHDKC_00104	4.43e-115	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HKDMHDKC_00105	1.1e-129	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKDMHDKC_00106	2.21e-57	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
HKDMHDKC_00107	6.11e-68	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
HKDMHDKC_00108	1.76e-193	-	-	-	S	-	-	-	Fic/DOC family
HKDMHDKC_00109	4.3e-185	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKDMHDKC_00110	3.65e-54	-	-	-	-	-	-	-	-
HKDMHDKC_00111	1.39e-174	-	-	-	-	-	-	-	-
HKDMHDKC_00112	1.28e-82	-	-	-	-	-	-	-	-
HKDMHDKC_00113	9.1e-65	-	-	-	S	-	-	-	MazG-like family
HKDMHDKC_00114	7.8e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HKDMHDKC_00115	2.25e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKDMHDKC_00116	1.43e-48	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKDMHDKC_00117	2.39e-64	-	-	-	-	-	-	-	-
HKDMHDKC_00118	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HKDMHDKC_00119	1.01e-110	yfhC	-	-	C	-	-	-	nitroreductase
HKDMHDKC_00120	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKDMHDKC_00121	5.46e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDMHDKC_00122	1.1e-181	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HKDMHDKC_00123	2.21e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKDMHDKC_00124	8.4e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
HKDMHDKC_00126	2.05e-136	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKDMHDKC_00127	1.15e-179	-	-	-	-	-	-	-	-
HKDMHDKC_00128	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKDMHDKC_00129	1.5e-56	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
HKDMHDKC_00130	1.42e-66	-	-	-	-	-	-	-	-
HKDMHDKC_00131	1.81e-38	-	-	-	-	-	-	-	-
HKDMHDKC_00132	1.57e-152	-	-	-	C	-	-	-	nitroreductase
HKDMHDKC_00133	0.0	-	-	-	C	-	-	-	FMN_bind
HKDMHDKC_00134	8.2e-214	-	-	-	K	-	-	-	LysR substrate binding domain
HKDMHDKC_00135	3.84e-200	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKDMHDKC_00136	1.75e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HKDMHDKC_00137	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HKDMHDKC_00138	4.47e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKDMHDKC_00139	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKDMHDKC_00140	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKDMHDKC_00141	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00142	6.34e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_00144	1.11e-163	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HKDMHDKC_00145	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HKDMHDKC_00146	1.02e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
HKDMHDKC_00147	4.14e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKDMHDKC_00148	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKDMHDKC_00149	2.26e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKDMHDKC_00150	4.61e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKDMHDKC_00151	6.42e-237	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKDMHDKC_00152	2.9e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKDMHDKC_00153	3.33e-217	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKDMHDKC_00154	2.49e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKDMHDKC_00155	1.11e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKDMHDKC_00156	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HKDMHDKC_00157	6.41e-197	yxeH	-	-	S	-	-	-	hydrolase
HKDMHDKC_00158	2.48e-215	-	-	-	S	-	-	-	DUF218 domain
HKDMHDKC_00159	7.47e-70	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HKDMHDKC_00160	2.49e-297	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HKDMHDKC_00161	8.88e-221	-	-	-	-	-	-	-	-
HKDMHDKC_00162	2.2e-171	-	-	-	-	-	-	-	-
HKDMHDKC_00163	1.27e-134	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKDMHDKC_00164	1.45e-30	-	-	-	-	-	-	-	-
HKDMHDKC_00165	1.55e-140	-	-	-	-	-	-	-	-
HKDMHDKC_00166	6.56e-185	-	-	-	-	-	-	-	-
HKDMHDKC_00167	1.46e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKDMHDKC_00168	2.1e-78	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HKDMHDKC_00169	2.67e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKDMHDKC_00170	1.15e-195	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKDMHDKC_00171	9.1e-156	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HKDMHDKC_00172	2.29e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKDMHDKC_00173	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKDMHDKC_00174	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HKDMHDKC_00175	1.82e-228	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HKDMHDKC_00176	4.14e-177	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKDMHDKC_00177	4.24e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKDMHDKC_00178	4.52e-128	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKDMHDKC_00179	1.67e-222	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HKDMHDKC_00180	3.98e-79	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HKDMHDKC_00181	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HKDMHDKC_00182	9.43e-201	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKDMHDKC_00183	1.71e-206	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKDMHDKC_00184	1.53e-139	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKDMHDKC_00185	4.33e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKDMHDKC_00186	1.14e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HKDMHDKC_00187	3.88e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKDMHDKC_00188	1e-43	-	-	-	-	-	-	-	-
HKDMHDKC_00189	2.52e-210	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
HKDMHDKC_00191	1.33e-99	-	-	-	S	-	-	-	HIRAN
HKDMHDKC_00192	1.33e-09	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HKDMHDKC_00193	1.53e-243	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKDMHDKC_00194	3.48e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKDMHDKC_00195	1.66e-214	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKDMHDKC_00196	5e-268	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKDMHDKC_00197	1.3e-286	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
HKDMHDKC_00198	2.15e-234	-	-	-	V	-	-	-	Abi-like protein
HKDMHDKC_00199	2.28e-31	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKDMHDKC_00200	7.2e-235	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKDMHDKC_00201	4.11e-229	-	-	-	S	-	-	-	Acyltransferase family
HKDMHDKC_00202	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKDMHDKC_00203	1.1e-281	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKDMHDKC_00204	1.08e-270	-	-	-	-	-	-	-	-
HKDMHDKC_00205	7.35e-249	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKDMHDKC_00206	2.05e-256	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKDMHDKC_00207	6.33e-254	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKDMHDKC_00208	4.29e-207	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HKDMHDKC_00209	5.28e-237	-	-	-	H	-	-	-	Glycosyl transferase family 11
HKDMHDKC_00210	3.49e-160	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HKDMHDKC_00211	2.18e-117	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HKDMHDKC_00212	1.21e-108	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HKDMHDKC_00213	2.06e-157	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HKDMHDKC_00214	5.69e-187	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKDMHDKC_00215	3.3e-162	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKDMHDKC_00216	5.62e-193	epsB	-	-	M	-	-	-	biosynthesis protein
HKDMHDKC_00217	5.1e-220	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKDMHDKC_00218	2.58e-103	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HKDMHDKC_00219	1.12e-212	-	-	-	-	-	-	-	-
HKDMHDKC_00220	3.15e-158	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HKDMHDKC_00221	6.2e-302	-	-	-	-	-	-	-	-
HKDMHDKC_00222	4.05e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKDMHDKC_00223	1.29e-107	-	-	-	-	-	-	-	-
HKDMHDKC_00224	3.98e-116	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKDMHDKC_00225	5.34e-134	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HKDMHDKC_00226	2.5e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKDMHDKC_00227	1.79e-278	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKDMHDKC_00228	6.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKDMHDKC_00229	2e-206	-	-	-	-	-	-	-	-
HKDMHDKC_00230	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKDMHDKC_00231	1.44e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKDMHDKC_00232	1.97e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKDMHDKC_00233	1.23e-229	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKDMHDKC_00234	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKDMHDKC_00235	5.23e-132	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HKDMHDKC_00236	1.45e-236	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKDMHDKC_00237	5.77e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKDMHDKC_00238	7.11e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HKDMHDKC_00239	7.67e-69	ylbG	-	-	S	-	-	-	UPF0298 protein
HKDMHDKC_00240	1.66e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKDMHDKC_00241	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKDMHDKC_00242	2.39e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKDMHDKC_00243	1.53e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HKDMHDKC_00244	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKDMHDKC_00245	5.63e-226	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKDMHDKC_00246	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKDMHDKC_00247	2.93e-150	-	-	-	S	-	-	-	repeat protein
HKDMHDKC_00248	4.52e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HKDMHDKC_00249	3e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKDMHDKC_00250	1.8e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HKDMHDKC_00251	4.29e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKDMHDKC_00252	1.68e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKDMHDKC_00253	1.22e-23	-	-	-	-	-	-	-	-
HKDMHDKC_00254	6.31e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HKDMHDKC_00255	3.24e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKDMHDKC_00256	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKDMHDKC_00257	2.05e-163	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HKDMHDKC_00258	3.41e-188	ylmH	-	-	S	-	-	-	S4 domain protein
HKDMHDKC_00259	1.93e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HKDMHDKC_00260	4.43e-95	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKDMHDKC_00261	7.39e-309	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKDMHDKC_00262	2.81e-313	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKDMHDKC_00263	4.13e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKDMHDKC_00264	2.01e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKDMHDKC_00265	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKDMHDKC_00266	1.82e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKDMHDKC_00267	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKDMHDKC_00268	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HKDMHDKC_00269	7.69e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKDMHDKC_00270	1.33e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKDMHDKC_00271	7.67e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HKDMHDKC_00272	3.35e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HKDMHDKC_00273	9.8e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
HKDMHDKC_00274	4.1e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HKDMHDKC_00275	2.19e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HKDMHDKC_00276	5.06e-144	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HKDMHDKC_00277	1.56e-160	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKDMHDKC_00278	5.72e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKDMHDKC_00279	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKDMHDKC_00280	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKDMHDKC_00281	4.76e-269	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
HKDMHDKC_00282	7.16e-161	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKDMHDKC_00283	2.67e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKDMHDKC_00284	1.5e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKDMHDKC_00285	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKDMHDKC_00287	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKDMHDKC_00288	1.21e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKDMHDKC_00289	3.11e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKDMHDKC_00290	2.34e-08	-	-	-	-	-	-	-	-
HKDMHDKC_00291	3.9e-106	uspA	-	-	T	-	-	-	universal stress protein
HKDMHDKC_00292	3.34e-287	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HKDMHDKC_00293	3.08e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HKDMHDKC_00294	6.72e-70	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HKDMHDKC_00295	2.97e-21	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HKDMHDKC_00296	1.01e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HKDMHDKC_00297	3e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HKDMHDKC_00298	2.1e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKDMHDKC_00299	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKDMHDKC_00300	2.1e-220	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKDMHDKC_00301	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKDMHDKC_00302	7.97e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKDMHDKC_00303	1.96e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKDMHDKC_00304	9.31e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKDMHDKC_00305	1.43e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKDMHDKC_00306	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKDMHDKC_00307	9.87e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKDMHDKC_00308	7.54e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKDMHDKC_00309	1.27e-250	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKDMHDKC_00310	5.77e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HKDMHDKC_00311	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HKDMHDKC_00312	2.07e-249	ampC	-	-	V	-	-	-	Beta-lactamase
HKDMHDKC_00315	2.98e-94	-	-	-	-	-	-	-	-
HKDMHDKC_00316	6.39e-141	-	-	-	EGP	-	-	-	Major Facilitator
HKDMHDKC_00317	2.79e-108	-	-	-	EGP	-	-	-	Major Facilitator
HKDMHDKC_00318	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKDMHDKC_00319	1.93e-139	vanZ	-	-	V	-	-	-	VanZ like family
HKDMHDKC_00320	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKDMHDKC_00321	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HKDMHDKC_00322	6.61e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HKDMHDKC_00323	9.78e-89	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKDMHDKC_00324	7.57e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKDMHDKC_00325	1.62e-100	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKDMHDKC_00326	4.11e-105	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HKDMHDKC_00327	8.38e-36	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HKDMHDKC_00328	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HKDMHDKC_00330	5.13e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKDMHDKC_00331	8.46e-239	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HKDMHDKC_00332	3.17e-113	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HKDMHDKC_00334	1.45e-88	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HKDMHDKC_00335	4.94e-54	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
HKDMHDKC_00336	1.65e-226	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HKDMHDKC_00337	7.04e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HKDMHDKC_00338	2.13e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HKDMHDKC_00339	1.11e-126	-	-	-	S	-	-	-	VanZ like family
HKDMHDKC_00340	1.18e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKDMHDKC_00341	2.74e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKDMHDKC_00342	1.07e-192	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HKDMHDKC_00343	5.95e-149	-	-	-	-	-	-	-	-
HKDMHDKC_00344	7.23e-242	-	-	-	S	-	-	-	Putative adhesin
HKDMHDKC_00345	1.13e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKDMHDKC_00346	2.49e-87	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKDMHDKC_00347	8.42e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKDMHDKC_00348	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKDMHDKC_00349	1.55e-224	ybbR	-	-	S	-	-	-	YbbR-like protein
HKDMHDKC_00350	1.29e-196	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKDMHDKC_00351	1.71e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDMHDKC_00352	5.35e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00353	1.04e-180	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00354	1.25e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKDMHDKC_00355	3.45e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKDMHDKC_00356	3.17e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKDMHDKC_00357	2.49e-110	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HKDMHDKC_00358	1.82e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HKDMHDKC_00359	7.98e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKDMHDKC_00360	3.3e-201	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKDMHDKC_00361	1.41e-120	-	-	-	-	-	-	-	-
HKDMHDKC_00362	1.8e-134	-	-	-	-	-	-	-	-
HKDMHDKC_00364	1.38e-138	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HKDMHDKC_00365	7.24e-102	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKDMHDKC_00366	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKDMHDKC_00367	1.07e-39	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKDMHDKC_00368	1.18e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKDMHDKC_00369	8.39e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKDMHDKC_00370	1.42e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HKDMHDKC_00371	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKDMHDKC_00372	2.15e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HKDMHDKC_00374	0.0	ycaM	-	-	E	-	-	-	amino acid
HKDMHDKC_00375	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKDMHDKC_00376	8.24e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKDMHDKC_00377	1.88e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HKDMHDKC_00378	3.19e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKDMHDKC_00379	1.44e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKDMHDKC_00380	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKDMHDKC_00381	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKDMHDKC_00382	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKDMHDKC_00383	1.66e-247	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKDMHDKC_00384	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKDMHDKC_00385	1.77e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKDMHDKC_00386	2.39e-229	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKDMHDKC_00391	3.1e-276	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKDMHDKC_00392	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HKDMHDKC_00393	1.7e-164	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HKDMHDKC_00394	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKDMHDKC_00395	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKDMHDKC_00396	1.82e-278	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HKDMHDKC_00397	2.27e-164	-	-	-	-	-	-	-	-
HKDMHDKC_00398	1.32e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKDMHDKC_00399	1.96e-161	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKDMHDKC_00400	5.83e-222	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKDMHDKC_00401	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKDMHDKC_00402	3.12e-220	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HKDMHDKC_00403	4.75e-67	-	-	-	-	-	-	-	-
HKDMHDKC_00404	4.65e-100	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKDMHDKC_00405	3.38e-76	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKDMHDKC_00407	3.04e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKDMHDKC_00408	3.72e-166	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
HKDMHDKC_00409	9.45e-145	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HKDMHDKC_00410	2.16e-108	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HKDMHDKC_00411	8.55e-247	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HKDMHDKC_00412	4.71e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKDMHDKC_00413	3.31e-212	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKDMHDKC_00414	4.43e-177	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
HKDMHDKC_00415	6.63e-188	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKDMHDKC_00416	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HKDMHDKC_00417	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HKDMHDKC_00418	2.64e-92	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDMHDKC_00419	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HKDMHDKC_00420	4.48e-102	-	-	-	K	-	-	-	acetyltransferase
HKDMHDKC_00421	1.57e-187	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKDMHDKC_00422	4.86e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1440)
HKDMHDKC_00423	1.99e-193	-	-	-	S	-	-	-	hydrolase
HKDMHDKC_00424	1.44e-98	-	-	-	K	-	-	-	Transcriptional regulator
HKDMHDKC_00425	2.78e-79	-	-	-	K	-	-	-	Transcriptional regulator
HKDMHDKC_00426	2.57e-307	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HKDMHDKC_00427	2.29e-176	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HKDMHDKC_00428	9.37e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HKDMHDKC_00429	2.86e-137	-	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HKDMHDKC_00430	5.07e-166	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
HKDMHDKC_00431	1.71e-111	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKDMHDKC_00432	6.32e-68	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKDMHDKC_00433	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKDMHDKC_00434	3.59e-52	-	-	-	-	-	-	-	-
HKDMHDKC_00435	4.16e-196	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
HKDMHDKC_00436	6.12e-76	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKDMHDKC_00437	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HKDMHDKC_00438	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDMHDKC_00439	3.04e-258	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HKDMHDKC_00440	1.31e-211	-	-	-	K	-	-	-	LysR family
HKDMHDKC_00441	0.0	-	-	-	C	-	-	-	FMN_bind
HKDMHDKC_00442	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKDMHDKC_00443	1.08e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HKDMHDKC_00444	1.23e-144	-	-	-	I	-	-	-	Acid phosphatase homologues
HKDMHDKC_00445	2.3e-276	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HKDMHDKC_00446	7.95e-45	-	-	-	-	-	-	-	-
HKDMHDKC_00447	4.11e-95	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKDMHDKC_00448	1.64e-108	-	-	-	-	-	-	-	-
HKDMHDKC_00449	5.75e-267	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HKDMHDKC_00451	5.16e-115	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKDMHDKC_00452	1.9e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKDMHDKC_00453	1.49e-194	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKDMHDKC_00454	2.38e-94	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKDMHDKC_00455	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKDMHDKC_00456	5.45e-232	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKDMHDKC_00457	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Glycosyl hydrolases family 31
HKDMHDKC_00458	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HKDMHDKC_00459	2.81e-265	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HKDMHDKC_00460	2.6e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
HKDMHDKC_00461	2.27e-98	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HKDMHDKC_00462	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_00463	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HKDMHDKC_00464	6.61e-190	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDMHDKC_00465	4.37e-176	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_00466	1.18e-191	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDMHDKC_00467	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00468	7.95e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00469	1.77e-199	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKDMHDKC_00470	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKDMHDKC_00471	3.51e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HKDMHDKC_00472	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDMHDKC_00473	1.65e-128	-	-	-	S	-	-	-	Putative adhesin
HKDMHDKC_00474	9.28e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HKDMHDKC_00475	9.09e-204	-	-	-	EGP	-	-	-	Major facilitator superfamily
HKDMHDKC_00476	9.4e-100	-	-	-	EGP	-	-	-	Major facilitator superfamily
HKDMHDKC_00478	7.42e-75	-	-	-	S	-	-	-	Enterocin A Immunity
HKDMHDKC_00479	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKDMHDKC_00480	3.34e-208	-	-	-	S	-	-	-	Phospholipase, patatin family
HKDMHDKC_00481	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00482	2.68e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_00483	2.8e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKDMHDKC_00484	2.89e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKDMHDKC_00485	1.24e-216	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKDMHDKC_00486	2.05e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HKDMHDKC_00487	3.84e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKDMHDKC_00488	2.13e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKDMHDKC_00489	4.1e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKDMHDKC_00490	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HKDMHDKC_00491	1.15e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKDMHDKC_00493	1.58e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKDMHDKC_00494	8.05e-166	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKDMHDKC_00495	5.75e-224	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HKDMHDKC_00496	2.4e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HKDMHDKC_00497	7.47e-70	-	-	-	S	-	-	-	Enterocin A Immunity
HKDMHDKC_00498	3.92e-178	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HKDMHDKC_00499	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKDMHDKC_00500	1.24e-153	-	-	-	C	-	-	-	nitroreductase
HKDMHDKC_00501	8.05e-171	-	-	-	-	-	-	-	-
HKDMHDKC_00502	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HKDMHDKC_00503	1.22e-132	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKDMHDKC_00504	2.29e-299	-	-	-	E	ko:K03294	-	ko00000	amino acid
HKDMHDKC_00505	3.55e-176	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKDMHDKC_00506	1.35e-278	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HKDMHDKC_00507	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDMHDKC_00510	1.4e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKDMHDKC_00511	3.13e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKDMHDKC_00512	4.75e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKDMHDKC_00513	2.09e-207	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HKDMHDKC_00514	6.47e-214	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HKDMHDKC_00515	1.94e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKDMHDKC_00516	3.18e-199	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKDMHDKC_00517	1.02e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_00518	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKDMHDKC_00519	4.54e-91	-	-	-	O	-	-	-	OsmC-like protein
HKDMHDKC_00520	1.52e-28	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HKDMHDKC_00521	2.97e-149	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HKDMHDKC_00522	1.44e-149	dltr	-	-	K	-	-	-	response regulator
HKDMHDKC_00523	3.86e-300	sptS	-	-	T	-	-	-	Histidine kinase
HKDMHDKC_00524	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKDMHDKC_00525	2.75e-74	-	-	-	-	-	-	-	-
HKDMHDKC_00526	8.93e-90	-	-	-	-	-	-	-	-
HKDMHDKC_00527	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HKDMHDKC_00528	1.1e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKDMHDKC_00529	1.13e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDMHDKC_00531	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKDMHDKC_00532	2.46e-95	-	-	-	-	-	-	-	-
HKDMHDKC_00533	6.22e-140	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HKDMHDKC_00534	1.78e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKDMHDKC_00535	2.83e-165	pnb	-	-	C	-	-	-	nitroreductase
HKDMHDKC_00536	5.18e-128	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKDMHDKC_00537	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKDMHDKC_00538	4.6e-102	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKDMHDKC_00539	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKDMHDKC_00540	6.93e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HKDMHDKC_00541	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKDMHDKC_00542	7.29e-215	-	-	-	GK	-	-	-	ROK family
HKDMHDKC_00543	1.12e-211	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKDMHDKC_00544	8.33e-225	-	-	-	I	-	-	-	Carboxylesterase family
HKDMHDKC_00545	2.31e-264	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKDMHDKC_00546	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKDMHDKC_00547	4.63e-74	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKDMHDKC_00548	1.59e-77	-	-	-	-	-	-	-	-
HKDMHDKC_00549	3.41e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HKDMHDKC_00550	4.96e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HKDMHDKC_00551	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HKDMHDKC_00552	4.08e-18	-	-	-	-	-	-	-	-
HKDMHDKC_00553	2.59e-313	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HKDMHDKC_00554	1.89e-192	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKDMHDKC_00555	1.23e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HKDMHDKC_00556	1.67e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKDMHDKC_00557	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HKDMHDKC_00558	1.56e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKDMHDKC_00559	6.05e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKDMHDKC_00560	1.47e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HKDMHDKC_00561	1.42e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKDMHDKC_00562	2.23e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKDMHDKC_00563	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKDMHDKC_00564	1.93e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKDMHDKC_00565	9.87e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKDMHDKC_00566	1.85e-199	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKDMHDKC_00567	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKDMHDKC_00568	8.55e-64	-	-	-	-	-	-	-	-
HKDMHDKC_00569	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKDMHDKC_00570	1.63e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKDMHDKC_00571	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKDMHDKC_00572	8.3e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKDMHDKC_00573	1.55e-310	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKDMHDKC_00574	2.6e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HKDMHDKC_00575	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKDMHDKC_00576	9.56e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKDMHDKC_00577	1.11e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKDMHDKC_00578	4.49e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HKDMHDKC_00579	9.04e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HKDMHDKC_00580	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKDMHDKC_00581	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HKDMHDKC_00582	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKDMHDKC_00583	1.01e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKDMHDKC_00584	6.2e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKDMHDKC_00585	4.35e-244	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKDMHDKC_00586	2.91e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKDMHDKC_00587	3.16e-232	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00588	2.73e-209	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDMHDKC_00589	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKDMHDKC_00590	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKDMHDKC_00591	5.24e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKDMHDKC_00592	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKDMHDKC_00593	1.78e-241	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKDMHDKC_00594	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKDMHDKC_00595	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKDMHDKC_00596	4.67e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKDMHDKC_00597	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKDMHDKC_00598	8.79e-125	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKDMHDKC_00599	3.13e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKDMHDKC_00600	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKDMHDKC_00601	3.68e-151	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKDMHDKC_00602	1.68e-98	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
HKDMHDKC_00603	1.35e-149	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HKDMHDKC_00604	3.88e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKDMHDKC_00605	9.78e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
HKDMHDKC_00606	3.41e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HKDMHDKC_00607	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDMHDKC_00608	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKDMHDKC_00609	1.31e-286	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKDMHDKC_00610	3.62e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HKDMHDKC_00611	1.87e-249	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HKDMHDKC_00612	1.07e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKDMHDKC_00613	4.15e-234	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKDMHDKC_00614	7.13e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKDMHDKC_00615	2.87e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKDMHDKC_00616	1.7e-175	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKDMHDKC_00617	3.37e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HKDMHDKC_00618	3.14e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HKDMHDKC_00619	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKDMHDKC_00620	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKDMHDKC_00621	2.25e-107	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HKDMHDKC_00622	6.72e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKDMHDKC_00623	2.17e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HKDMHDKC_00624	2.2e-62	-	-	-	J	-	-	-	ribosomal protein
HKDMHDKC_00625	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKDMHDKC_00626	6.74e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKDMHDKC_00627	2.1e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKDMHDKC_00628	4.29e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKDMHDKC_00629	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HKDMHDKC_00630	1.71e-155	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HKDMHDKC_00631	4.59e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKDMHDKC_00632	9.65e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKDMHDKC_00633	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKDMHDKC_00634	9.97e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKDMHDKC_00635	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKDMHDKC_00636	6.6e-159	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HKDMHDKC_00637	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HKDMHDKC_00638	1.02e-124	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKDMHDKC_00639	0.0	potE	-	-	E	-	-	-	Amino Acid
HKDMHDKC_00640	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKDMHDKC_00641	1.21e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKDMHDKC_00642	3.2e-126	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKDMHDKC_00643	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKDMHDKC_00644	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKDMHDKC_00645	4.36e-204	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HKDMHDKC_00647	5.12e-132	-	-	-	I	-	-	-	PAP2 superfamily
HKDMHDKC_00648	6.08e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKDMHDKC_00649	9.84e-41	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HKDMHDKC_00650	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKDMHDKC_00651	4.03e-64	-	-	-	K	-	-	-	Helix-turn-helix domain
HKDMHDKC_00652	1.14e-195	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKDMHDKC_00653	5.81e-125	-	-	-	L	-	-	-	nuclease
HKDMHDKC_00654	5.71e-201	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKDMHDKC_00655	9.17e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKDMHDKC_00656	2.57e-126	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00657	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKDMHDKC_00658	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKDMHDKC_00659	1.54e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKDMHDKC_00660	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKDMHDKC_00661	4.36e-242	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HKDMHDKC_00662	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKDMHDKC_00663	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HKDMHDKC_00664	1.7e-113	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKDMHDKC_00665	4.27e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HKDMHDKC_00666	2.32e-86	-	-	-	-	-	-	-	-
HKDMHDKC_00667	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKDMHDKC_00668	2.88e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKDMHDKC_00669	4.28e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKDMHDKC_00670	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKDMHDKC_00671	3.8e-118	-	-	-	-	-	-	-	-
HKDMHDKC_00672	1.22e-107	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKDMHDKC_00673	3.4e-58	-	-	-	-	-	-	-	-
HKDMHDKC_00674	2.11e-89	-	-	-	-	-	-	-	-
HKDMHDKC_00675	4.27e-85	-	-	-	S	-	-	-	Domain of unknown function DUF1828
HKDMHDKC_00676	2.98e-140	-	-	-	S	-	-	-	Rib/alpha-like repeat
HKDMHDKC_00677	4.62e-316	yagE	-	-	E	-	-	-	amino acid
HKDMHDKC_00678	4.45e-150	-	-	-	GM	-	-	-	NmrA-like family
HKDMHDKC_00679	3.3e-137	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HKDMHDKC_00680	1.01e-222	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HKDMHDKC_00681	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKDMHDKC_00682	1.08e-305	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKDMHDKC_00683	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HKDMHDKC_00684	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKDMHDKC_00685	5.02e-185	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKDMHDKC_00686	1.1e-62	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HKDMHDKC_00687	5.51e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKDMHDKC_00688	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKDMHDKC_00689	1.57e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKDMHDKC_00690	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HKDMHDKC_00692	1.19e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKDMHDKC_00693	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKDMHDKC_00694	1.65e-211	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HKDMHDKC_00695	1.17e-218	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HKDMHDKC_00696	1.95e-82	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
HKDMHDKC_00697	5.22e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKDMHDKC_00698	3.57e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKDMHDKC_00699	8.87e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKDMHDKC_00700	1.39e-94	-	-	-	M	-	-	-	Lysin motif
HKDMHDKC_00701	7.54e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKDMHDKC_00702	1.03e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKDMHDKC_00703	5.27e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKDMHDKC_00704	1.6e-306	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKDMHDKC_00705	7.91e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKDMHDKC_00706	1.27e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HKDMHDKC_00707	0.0	-	-	-	KL	-	-	-	domain protein
HKDMHDKC_00708	2.2e-195	-	-	-	-	-	-	-	-
HKDMHDKC_00709	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKDMHDKC_00710	1.25e-155	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKDMHDKC_00711	2.91e-229	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKDMHDKC_00712	2.58e-148	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HKDMHDKC_00713	0.0	-	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	EcoEI R protein C-terminal
HKDMHDKC_00714	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HKDMHDKC_00715	0.0	-	-	-	C	-	-	-	FMN_bind
HKDMHDKC_00716	7.96e-135	-	-	-	-	-	-	-	-
HKDMHDKC_00717	3.51e-142	-	-	-	-	-	-	-	-
HKDMHDKC_00718	8.13e-207	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKDMHDKC_00719	1.66e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKDMHDKC_00720	1.38e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HKDMHDKC_00721	2.31e-196	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKDMHDKC_00722	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HKDMHDKC_00723	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HKDMHDKC_00724	4.91e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKDMHDKC_00725	7.68e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKDMHDKC_00726	1.3e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HKDMHDKC_00727	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKDMHDKC_00728	1.9e-316	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKDMHDKC_00729	1.09e-221	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HKDMHDKC_00730	7.75e-115	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKDMHDKC_00731	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKDMHDKC_00732	3.03e-231	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKDMHDKC_00733	1.19e-134	-	-	-	K	-	-	-	LysR substrate binding domain
HKDMHDKC_00734	1.17e-129	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HKDMHDKC_00736	6.86e-92	-	-	-	-	-	-	-	-
HKDMHDKC_00737	1.09e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKDMHDKC_00738	5.9e-94	-	-	-	K	-	-	-	Transcriptional regulator
HKDMHDKC_00739	6.05e-69	-	-	-	-	-	-	-	-
HKDMHDKC_00740	3.75e-57	-	-	-	-	-	-	-	-
HKDMHDKC_00741	5.57e-55	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
HKDMHDKC_00742	2.08e-179	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKDMHDKC_00743	3.29e-146	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_00744	2.18e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HKDMHDKC_00745	6.43e-127	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKDMHDKC_00746	3.18e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKDMHDKC_00747	1.27e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKDMHDKC_00748	1.21e-144	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKDMHDKC_00749	0.0	-	-	-	S	-	-	-	domain, Protein
HKDMHDKC_00751	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKDMHDKC_00752	2.08e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKDMHDKC_00753	1.04e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HKDMHDKC_00754	4.56e-266	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKDMHDKC_00755	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKDMHDKC_00756	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKDMHDKC_00757	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKDMHDKC_00758	7.47e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKDMHDKC_00759	2.5e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKDMHDKC_00760	4.55e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKDMHDKC_00761	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HKDMHDKC_00762	8.13e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKDMHDKC_00763	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKDMHDKC_00764	2.56e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKDMHDKC_00765	1.19e-280	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HKDMHDKC_00766	0.0	-	-	-	-	-	-	-	-
HKDMHDKC_00767	2.64e-151	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HKDMHDKC_00769	6.94e-146	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HKDMHDKC_00770	7.49e-29	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKDMHDKC_00771	1.56e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
HKDMHDKC_00772	1.49e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
HKDMHDKC_00773	1.39e-256	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKDMHDKC_00775	5.09e-285	-	-	-	S	-	-	-	Sterol carrier protein domain
HKDMHDKC_00776	6.39e-150	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HKDMHDKC_00777	2.7e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKDMHDKC_00778	1.58e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKDMHDKC_00779	4.34e-198	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HKDMHDKC_00780	1.92e-26	-	-	-	-	-	-	-	-
HKDMHDKC_00781	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HKDMHDKC_00782	1.72e-214	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKDMHDKC_00783	3.18e-19	-	-	-	S	-	-	-	CsbD-like
HKDMHDKC_00784	1.29e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
HKDMHDKC_00785	9.2e-207	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKDMHDKC_00786	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HKDMHDKC_00787	4.93e-212	-	-	-	S	-	-	-	Alpha beta hydrolase
HKDMHDKC_00788	3.66e-54	-	-	-	-	-	-	-	-
HKDMHDKC_00789	2.88e-229	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKDMHDKC_00790	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HKDMHDKC_00791	2.28e-271	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKDMHDKC_00792	1.8e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKDMHDKC_00793	1.71e-246	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKDMHDKC_00794	0.0	-	-	-	S	-	-	-	domain, Protein
HKDMHDKC_00795	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKDMHDKC_00796	0.0	-	-	-	M	-	-	-	domain protein
HKDMHDKC_00797	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HKDMHDKC_00798	1.37e-220	-	-	-	K	-	-	-	LysR substrate binding domain
HKDMHDKC_00799	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKDMHDKC_00800	1.55e-309	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKDMHDKC_00801	1.1e-170	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKDMHDKC_00802	4.14e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKDMHDKC_00803	1.18e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKDMHDKC_00804	7.51e-238	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HKDMHDKC_00805	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKDMHDKC_00806	2.13e-75	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKDMHDKC_00807	2.48e-166	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKDMHDKC_00808	1.42e-211	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HKDMHDKC_00809	2.51e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
HKDMHDKC_00810	3.05e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
HKDMHDKC_00811	9.16e-202	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HKDMHDKC_00812	1.3e-194	-	-	-	I	-	-	-	Acyl-transferase
HKDMHDKC_00814	3.03e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKDMHDKC_00815	1.65e-182	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKDMHDKC_00816	1.77e-211	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKDMHDKC_00817	0.0	yycH	-	-	S	-	-	-	YycH protein
HKDMHDKC_00818	2.3e-190	yycI	-	-	S	-	-	-	YycH protein
HKDMHDKC_00819	6.41e-193	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HKDMHDKC_00820	1.04e-263	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HKDMHDKC_00821	3.66e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKDMHDKC_00822	2.2e-142	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKDMHDKC_00823	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_00824	3.01e-124	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HKDMHDKC_00825	3.49e-219	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKDMHDKC_00826	5.77e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKDMHDKC_00827	7.65e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKDMHDKC_00828	4.66e-240	ysdE	-	-	P	-	-	-	Citrate transporter
HKDMHDKC_00829	6.45e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKDMHDKC_00830	1.14e-23	-	-	-	-	-	-	-	-
HKDMHDKC_00831	1.57e-199	-	-	-	-	-	-	-	-
HKDMHDKC_00833	4.47e-313	-	-	-	M	-	-	-	Glycosyl transferase
HKDMHDKC_00834	1.09e-272	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HKDMHDKC_00835	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HKDMHDKC_00836	2.73e-208	-	-	-	L	-	-	-	HNH nucleases
HKDMHDKC_00837	8.61e-176	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_00838	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00839	3.97e-136	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HKDMHDKC_00840	5.23e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HKDMHDKC_00841	2.16e-168	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HKDMHDKC_00842	5.26e-123	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HKDMHDKC_00843	1.63e-172	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HKDMHDKC_00844	1.33e-104	-	-	-	-	-	-	-	-
HKDMHDKC_00845	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKDMHDKC_00846	1.81e-159	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HKDMHDKC_00847	2.39e-225	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDMHDKC_00848	3.86e-187	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKDMHDKC_00849	4.75e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HKDMHDKC_00850	3.33e-205	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKDMHDKC_00851	5.7e-160	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HKDMHDKC_00852	9.68e-83	-	-	-	-	-	-	-	-
HKDMHDKC_00853	7.71e-231	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKDMHDKC_00854	8.76e-283	-	-	-	S	-	-	-	CAAX protease self-immunity
HKDMHDKC_00855	4.1e-307	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKDMHDKC_00856	4.82e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDMHDKC_00857	8.47e-180	-	-	-	-	-	-	-	-
HKDMHDKC_00858	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HKDMHDKC_00859	6.59e-265	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKDMHDKC_00860	1.03e-151	-	-	-	-	-	-	-	-
HKDMHDKC_00861	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKDMHDKC_00862	1.02e-239	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HKDMHDKC_00863	1.61e-155	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HKDMHDKC_00864	6.44e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKDMHDKC_00865	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HKDMHDKC_00866	2.04e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HKDMHDKC_00867	5.87e-276	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
HKDMHDKC_00868	8.85e-290	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKDMHDKC_00869	5.59e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKDMHDKC_00870	1.87e-196	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKDMHDKC_00871	2.13e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKDMHDKC_00872	1.6e-89	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKDMHDKC_00873	3.49e-23	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKDMHDKC_00874	8.35e-277	-	-	-	S	-	-	-	zinc-ribbon domain
HKDMHDKC_00875	2.07e-242	-	-	-	-	-	-	-	-
HKDMHDKC_00876	9.02e-113	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HKDMHDKC_00877	1.89e-129	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKDMHDKC_00878	4.26e-171	-	-	-	K	-	-	-	UTRA domain
HKDMHDKC_00879	3.05e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKDMHDKC_00880	4.96e-113	usp5	-	-	T	-	-	-	universal stress protein
HKDMHDKC_00882	9.6e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HKDMHDKC_00883	2.58e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HKDMHDKC_00884	2.46e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDMHDKC_00885	8.69e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDMHDKC_00886	6.97e-107	-	-	-	-	-	-	-	-
HKDMHDKC_00887	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKDMHDKC_00888	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKDMHDKC_00889	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HKDMHDKC_00890	2.3e-83	-	-	-	-	-	-	-	-
HKDMHDKC_00891	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HKDMHDKC_00892	8.75e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKDMHDKC_00893	1.83e-134	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKDMHDKC_00894	4.42e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HKDMHDKC_00895	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKDMHDKC_00896	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKDMHDKC_00897	2.19e-290	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKDMHDKC_00898	9.39e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HKDMHDKC_00899	0.0	-	-	-	D	-	-	-	transport
HKDMHDKC_00900	9.83e-175	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKDMHDKC_00901	6.42e-210	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HKDMHDKC_00902	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKDMHDKC_00903	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKDMHDKC_00904	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HKDMHDKC_00905	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HKDMHDKC_00906	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKDMHDKC_00907	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKDMHDKC_00908	1.06e-95	-	-	-	-	-	-	-	-
HKDMHDKC_00909	1.47e-162	-	-	-	-	-	-	-	-
HKDMHDKC_00910	1.75e-39	-	-	-	-	-	-	-	-
HKDMHDKC_00911	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HKDMHDKC_00912	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKDMHDKC_00913	0.0	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKDMHDKC_00914	2.55e-185	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HKDMHDKC_00915	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HKDMHDKC_00916	6.12e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKDMHDKC_00917	2.11e-175	-	-	-	-	-	-	-	-
HKDMHDKC_00918	3.41e-193	-	-	-	-	-	-	-	-
HKDMHDKC_00919	2.22e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HKDMHDKC_00920	1.11e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKDMHDKC_00921	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKDMHDKC_00922	5.36e-92	-	-	-	S	-	-	-	GtrA-like protein
HKDMHDKC_00923	1.56e-227	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HKDMHDKC_00924	7.1e-152	-	-	-	-	-	-	-	-
HKDMHDKC_00925	2.21e-195	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKDMHDKC_00926	4.25e-219	-	-	-	G	-	-	-	Aldose 1-epimerase
HKDMHDKC_00927	3.28e-260	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKDMHDKC_00928	1.13e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKDMHDKC_00929	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HKDMHDKC_00930	9.21e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKDMHDKC_00932	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKDMHDKC_00933	2.24e-160	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKDMHDKC_00934	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKDMHDKC_00935	8.46e-81	-	-	-	-	-	-	-	-
HKDMHDKC_00936	4.87e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKDMHDKC_00937	1.47e-100	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKDMHDKC_00938	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDMHDKC_00939	2.08e-105	-	-	-	-	-	-	-	-
HKDMHDKC_00940	1.29e-315	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDMHDKC_00941	3.99e-166	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HKDMHDKC_00942	2.83e-57	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKDMHDKC_00943	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDMHDKC_00944	1.1e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HKDMHDKC_00945	1.76e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HKDMHDKC_00946	2.42e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKDMHDKC_00947	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDMHDKC_00948	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDMHDKC_00949	3.8e-202	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKDMHDKC_00950	2.21e-148	-	-	-	-	-	-	-	-
HKDMHDKC_00952	2.85e-147	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
HKDMHDKC_00953	4.06e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKDMHDKC_00954	6.82e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HKDMHDKC_00955	1.52e-129	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HKDMHDKC_00956	1.44e-114	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HKDMHDKC_00957	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKDMHDKC_00958	2.07e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HKDMHDKC_00959	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKDMHDKC_00960	3.56e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKDMHDKC_00961	2.99e-49	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HKDMHDKC_00962	7.77e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HKDMHDKC_00963	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKDMHDKC_00964	9.21e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKDMHDKC_00965	1.05e-227	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKDMHDKC_00966	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKDMHDKC_00967	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKDMHDKC_00968	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKDMHDKC_00969	6.6e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKDMHDKC_00970	4.76e-269	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKDMHDKC_00971	1.58e-293	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKDMHDKC_00972	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDMHDKC_00973	2.93e-199	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKDMHDKC_00974	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HKDMHDKC_00975	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKDMHDKC_00976	4.73e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HKDMHDKC_00977	3.78e-92	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKDMHDKC_00978	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKDMHDKC_00979	6.24e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKDMHDKC_00980	4.58e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HKDMHDKC_00981	1.66e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKDMHDKC_00982	1.59e-172	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HKDMHDKC_00983	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKDMHDKC_00985	5.2e-229	-	-	-	K	-	-	-	Helix-turn-helix
HKDMHDKC_00986	7.98e-50	-	-	-	-	-	-	-	-
HKDMHDKC_00987	9.94e-90	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HKDMHDKC_00988	1.63e-121	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDMHDKC_00989	6.29e-146	-	-	-	S	-	-	-	Flavodoxin-like fold
HKDMHDKC_00990	7.78e-63	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HKDMHDKC_00992	9.45e-67	-	-	-	-	-	-	-	-
HKDMHDKC_00993	5.66e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HKDMHDKC_00994	3.72e-86	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HKDMHDKC_00995	2.08e-127	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKDMHDKC_00996	1.97e-123	-	-	-	-	-	-	-	-
HKDMHDKC_00997	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKDMHDKC_00998	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKDMHDKC_00999	9.92e-266	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKDMHDKC_01000	1.64e-52	-	-	-	-	-	-	-	-
HKDMHDKC_01001	4.86e-28	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKDMHDKC_01002	4.68e-238	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKDMHDKC_01003	1.67e-101	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HKDMHDKC_01004	4.92e-104	-	-	-	-	-	-	-	-
HKDMHDKC_01006	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKDMHDKC_01007	2.21e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKDMHDKC_01008	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKDMHDKC_01009	5.27e-241	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKDMHDKC_01010	1.2e-182	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKDMHDKC_01011	1.55e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_01012	0.0	-	-	-	E	-	-	-	amino acid
HKDMHDKC_01013	1.28e-54	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKDMHDKC_01014	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKDMHDKC_01015	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKDMHDKC_01016	3.03e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKDMHDKC_01017	1.69e-278	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKDMHDKC_01018	5.46e-161	-	-	-	S	-	-	-	(CBS) domain
HKDMHDKC_01019	2.31e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKDMHDKC_01020	2.68e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKDMHDKC_01021	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKDMHDKC_01022	8.68e-47	yabO	-	-	J	-	-	-	S4 domain protein
HKDMHDKC_01023	5.29e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HKDMHDKC_01024	3.27e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
HKDMHDKC_01025	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKDMHDKC_01026	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKDMHDKC_01027	0.0	-	-	-	S	-	-	-	membrane
HKDMHDKC_01028	1.66e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKDMHDKC_01029	1.36e-245	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKDMHDKC_01030	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKDMHDKC_01033	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKDMHDKC_01034	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKDMHDKC_01035	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKDMHDKC_01036	1.28e-154	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HKDMHDKC_01037	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKDMHDKC_01038	1.14e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKDMHDKC_01039	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKDMHDKC_01040	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKDMHDKC_01041	5.06e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKDMHDKC_01042	3.16e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKDMHDKC_01043	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKDMHDKC_01044	4.88e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKDMHDKC_01045	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKDMHDKC_01046	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKDMHDKC_01047	7.46e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKDMHDKC_01048	4.26e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKDMHDKC_01049	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKDMHDKC_01050	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKDMHDKC_01051	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKDMHDKC_01052	1.67e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKDMHDKC_01053	4.3e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKDMHDKC_01054	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKDMHDKC_01055	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKDMHDKC_01056	6.14e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKDMHDKC_01057	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKDMHDKC_01058	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKDMHDKC_01059	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HKDMHDKC_01060	8.21e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKDMHDKC_01061	2.42e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKDMHDKC_01062	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKDMHDKC_01063	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKDMHDKC_01064	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HKDMHDKC_01065	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKDMHDKC_01066	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKDMHDKC_01067	2.19e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKDMHDKC_01068	3.85e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKDMHDKC_01069	1.1e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKDMHDKC_01070	1.86e-208	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKDMHDKC_01071	2.19e-180	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKDMHDKC_01072	8.78e-195	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKDMHDKC_01073	7.82e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKDMHDKC_01074	7.96e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKDMHDKC_01075	1.8e-104	-	-	-	-	-	-	-	-
HKDMHDKC_01076	5.1e-206	-	-	-	GM	-	-	-	NmrA-like family
HKDMHDKC_01077	1.27e-141	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HKDMHDKC_01078	1.83e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HKDMHDKC_01079	5.56e-70	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HKDMHDKC_01080	5.88e-199	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HKDMHDKC_01081	2.66e-56	-	-	-	-	-	-	-	-
HKDMHDKC_01082	1.33e-35	-	-	-	-	-	-	-	-
HKDMHDKC_01083	5.21e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKDMHDKC_01084	1.2e-236	-	-	-	S	-	-	-	AAA domain
HKDMHDKC_01085	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKDMHDKC_01086	6.34e-132	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HKDMHDKC_01087	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKDMHDKC_01088	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKDMHDKC_01089	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKDMHDKC_01090	2.73e-102	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKDMHDKC_01091	1.62e-179	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKDMHDKC_01092	4.51e-199	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
HKDMHDKC_01093	5.42e-75	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKDMHDKC_01094	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HKDMHDKC_01095	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDMHDKC_01096	3.38e-128	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
HKDMHDKC_01097	1.19e-45	-	-	-	-	-	-	-	-
HKDMHDKC_01098	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HKDMHDKC_01099	6.78e-270	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HKDMHDKC_01100	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKDMHDKC_01101	8.29e-292	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKDMHDKC_01102	6.02e-246	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKDMHDKC_01103	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKDMHDKC_01104	9.78e-18	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKDMHDKC_01105	2.58e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKDMHDKC_01106	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKDMHDKC_01107	6.1e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKDMHDKC_01108	1.38e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKDMHDKC_01109	1.29e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HKDMHDKC_01110	5.9e-188	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKDMHDKC_01111	2.35e-126	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKDMHDKC_01112	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKDMHDKC_01113	1.02e-198	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
HKDMHDKC_01114	3.25e-44	-	-	-	-	-	-	-	-
HKDMHDKC_01115	3.19e-145	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HKDMHDKC_01116	6.96e-33	-	-	-	-	-	-	-	-
HKDMHDKC_01117	2.52e-106	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKDMHDKC_01118	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKDMHDKC_01119	9.41e-69	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKDMHDKC_01120	1.53e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKDMHDKC_01121	3.68e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HKDMHDKC_01122	7.09e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKDMHDKC_01123	8.23e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HKDMHDKC_01124	1.39e-197	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKDMHDKC_01125	3.89e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HKDMHDKC_01126	8.76e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKDMHDKC_01127	2.57e-168	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HKDMHDKC_01128	8.12e-113	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKDMHDKC_01129	3.02e-170	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HKDMHDKC_01130	3.43e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HKDMHDKC_01131	8.61e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKDMHDKC_01132	6.62e-11	-	-	-	D	-	-	-	nuclear chromosome segregation
HKDMHDKC_01133	2.34e-11	-	-	-	D	-	-	-	nuclear chromosome segregation
HKDMHDKC_01134	6.8e-219	-	-	-	-	-	-	-	-
HKDMHDKC_01135	3.45e-150	-	-	-	-	-	-	-	-
HKDMHDKC_01136	3.27e-306	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKDMHDKC_01137	1.49e-64	-	-	-	-	-	-	-	-
HKDMHDKC_01138	1.2e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HKDMHDKC_01139	8.5e-242	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKDMHDKC_01140	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKDMHDKC_01141	3.38e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKDMHDKC_01142	1.53e-102	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HKDMHDKC_01143	2.75e-64	-	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
HKDMHDKC_01144	1.01e-71	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HKDMHDKC_01145	3.25e-298	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKDMHDKC_01146	2.19e-196	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKDMHDKC_01147	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HKDMHDKC_01148	0.0	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDMHDKC_01149	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
HKDMHDKC_01150	6.18e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKDMHDKC_01151	1.51e-100	-	-	-	-	-	-	-	-
HKDMHDKC_01152	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HKDMHDKC_01153	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKDMHDKC_01154	1.55e-133	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKDMHDKC_01155	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKDMHDKC_01156	2.75e-167	-	-	-	S	-	-	-	membrane
HKDMHDKC_01157	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKDMHDKC_01158	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKDMHDKC_01159	5.96e-09	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKDMHDKC_01160	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKDMHDKC_01161	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
HKDMHDKC_01162	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKDMHDKC_01163	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKDMHDKC_01164	1.26e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKDMHDKC_01165	9.5e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKDMHDKC_01166	1.08e-67	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKDMHDKC_01167	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKDMHDKC_01168	1.79e-267	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKDMHDKC_01169	2.44e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HKDMHDKC_01170	3.84e-299	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKDMHDKC_01171	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKDMHDKC_01172	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HKDMHDKC_01173	1.01e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKDMHDKC_01174	1.27e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HKDMHDKC_01175	1.33e-118	cvpA	-	-	S	-	-	-	Colicin V production protein
HKDMHDKC_01176	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKDMHDKC_01177	8.93e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKDMHDKC_01178	2.57e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HKDMHDKC_01179	1.14e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKDMHDKC_01180	4.91e-150	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKDMHDKC_01181	1.06e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKDMHDKC_01182	1.51e-203	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HKDMHDKC_01183	2.54e-33	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKDMHDKC_01184	1.47e-67	-	-	-	-	-	-	-	-
HKDMHDKC_01185	1.54e-270	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKDMHDKC_01186	2.52e-229	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HKDMHDKC_01187	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HKDMHDKC_01188	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
HKDMHDKC_01189	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HKDMHDKC_01190	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HKDMHDKC_01191	3.99e-74	-	-	-	-	-	-	-	-
HKDMHDKC_01192	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKDMHDKC_01193	1.44e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HKDMHDKC_01194	4.87e-190	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKDMHDKC_01195	1.62e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HKDMHDKC_01196	1.45e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HKDMHDKC_01197	8.83e-230	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HKDMHDKC_01198	3.37e-68	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
HKDMHDKC_01199	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKDMHDKC_01200	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
HKDMHDKC_01201	1.76e-199	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKDMHDKC_01202	4.61e-308	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDMHDKC_01203	7.34e-54	-	-	-	-	-	-	-	-
HKDMHDKC_01204	1.52e-274	-	-	-	E	-	-	-	Major Facilitator Superfamily
HKDMHDKC_01205	2.47e-223	pbpX2	-	-	V	-	-	-	Beta-lactamase
HKDMHDKC_01206	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKDMHDKC_01207	3.63e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKDMHDKC_01208	9.88e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HKDMHDKC_01209	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKDMHDKC_01210	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HKDMHDKC_01211	4.82e-60	-	-	-	-	-	-	-	-
HKDMHDKC_01212	5.68e-260	-	-	-	S	-	-	-	Membrane
HKDMHDKC_01213	7.91e-78	-	-	-	-	-	-	-	-
HKDMHDKC_01214	8.97e-66	-	-	-	-	-	-	-	-
HKDMHDKC_01215	9.94e-60	-	-	-	-	-	-	-	-
HKDMHDKC_01217	2.47e-112	ykuL	-	-	S	-	-	-	(CBS) domain
HKDMHDKC_01218	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HKDMHDKC_01219	1.39e-257	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HKDMHDKC_01221	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HKDMHDKC_01222	1.24e-204	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKDMHDKC_01223	3.3e-36	-	-	-	-	-	-	-	-
HKDMHDKC_01224	8.28e-47	-	-	-	-	-	-	-	-
HKDMHDKC_01225	1.03e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKDMHDKC_01226	1.75e-202	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HKDMHDKC_01227	3.9e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HKDMHDKC_01228	1.66e-303	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKDMHDKC_01229	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HKDMHDKC_01230	6.45e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HKDMHDKC_01231	8.24e-137	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDMHDKC_01232	7.17e-258	-	-	-	S	-	-	-	DUF218 domain
HKDMHDKC_01233	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_01234	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HKDMHDKC_01235	1.05e-231	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HKDMHDKC_01236	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKDMHDKC_01237	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKDMHDKC_01238	6.33e-226	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKDMHDKC_01239	4.97e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKDMHDKC_01240	2.01e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HKDMHDKC_01241	2.8e-256	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HKDMHDKC_01242	8.85e-226	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKDMHDKC_01243	9.29e-250	-	-	-	V	-	-	-	Beta-lactamase
HKDMHDKC_01244	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDMHDKC_01245	1.05e-203	gspK	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HKDMHDKC_01246	1.04e-270	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKDMHDKC_01247	1.84e-196	-	-	-	S	-	-	-	Putative esterase
HKDMHDKC_01248	1.13e-249	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HKDMHDKC_01249	1.05e-171	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKDMHDKC_01250	9.42e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKDMHDKC_01251	9.68e-173	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKDMHDKC_01252	7.88e-24	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKDMHDKC_01253	2.53e-206	-	-	-	S	-	-	-	Aldo/keto reductase family
HKDMHDKC_01254	1.26e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKDMHDKC_01255	8.74e-155	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HKDMHDKC_01256	4.15e-162	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HKDMHDKC_01257	1.45e-303	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKDMHDKC_01258	6.61e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKDMHDKC_01260	4.19e-161	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKDMHDKC_01261	5.76e-296	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKDMHDKC_01262	1.58e-60	-	-	-	I	-	-	-	bis(5'-adenosyl)-triphosphatase activity
HKDMHDKC_01263	7.1e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKDMHDKC_01264	8.45e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKDMHDKC_01265	1.37e-116	-	-	-	-	-	-	-	-
HKDMHDKC_01266	2.26e-117	-	-	-	-	-	-	-	-
HKDMHDKC_01267	3.09e-102	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HKDMHDKC_01268	4.35e-86	-	-	-	S	-	-	-	Cupredoxin-like domain
HKDMHDKC_01269	6.31e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HKDMHDKC_01270	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKDMHDKC_01271	1.29e-199	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HKDMHDKC_01272	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKDMHDKC_01273	0.0	-	-	-	E	-	-	-	Amino acid permease
HKDMHDKC_01274	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HKDMHDKC_01275	1.67e-315	ynbB	-	-	P	-	-	-	aluminum resistance
HKDMHDKC_01276	1.13e-98	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKDMHDKC_01277	2.63e-296	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HKDMHDKC_01278	7.94e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKDMHDKC_01279	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKDMHDKC_01280	1.98e-149	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HKDMHDKC_01281	9.66e-138	-	-	-	-	-	-	-	-
HKDMHDKC_01282	1.27e-195	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
HKDMHDKC_01283	7.78e-267	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKDMHDKC_01284	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKDMHDKC_01285	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKDMHDKC_01286	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKDMHDKC_01287	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKDMHDKC_01288	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKDMHDKC_01289	1.7e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKDMHDKC_01290	3.62e-79	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKDMHDKC_01291	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HKDMHDKC_01292	4.24e-298	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKDMHDKC_01293	3.7e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKDMHDKC_01294	0.0	-	-	-	E	-	-	-	Amino Acid
HKDMHDKC_01295	4.63e-173	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_01296	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKDMHDKC_01297	6.19e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HKDMHDKC_01298	6e-35	-	-	-	-	-	-	-	-
HKDMHDKC_01299	5.76e-70	-	-	-	-	-	-	-	-
HKDMHDKC_01300	6.23e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKDMHDKC_01301	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKDMHDKC_01302	2.81e-165	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKDMHDKC_01303	1.38e-186	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKDMHDKC_01304	4.84e-60	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKDMHDKC_01305	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKDMHDKC_01306	4.12e-316	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKDMHDKC_01307	4.02e-208	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKDMHDKC_01309	7.5e-153	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HKDMHDKC_01310	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKDMHDKC_01311	9.08e-176	-	-	-	S	-	-	-	Peptidase_C39 like family
HKDMHDKC_01312	1.97e-159	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKDMHDKC_01313	4.36e-105	-	-	-	L	-	-	-	MgsA AAA+ ATPase C terminal
HKDMHDKC_01314	3.14e-311	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDMHDKC_01315	9.65e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKDMHDKC_01316	7.9e-212	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKDMHDKC_01317	3.93e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKDMHDKC_01320	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
HKDMHDKC_01321	7.94e-202	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKDMHDKC_01322	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDMHDKC_01323	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDMHDKC_01324	2.22e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HKDMHDKC_01325	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKDMHDKC_01326	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HKDMHDKC_01327	1.73e-89	-	-	-	-	-	-	-	-
HKDMHDKC_01328	1.2e-30	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKDMHDKC_01329	4.41e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKDMHDKC_01330	2.47e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HKDMHDKC_01331	3.52e-303	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKDMHDKC_01332	4.63e-169	-	-	-	S	-	-	-	PAS domain
HKDMHDKC_01333	5.83e-205	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKDMHDKC_01334	1.11e-70	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKDMHDKC_01335	3.06e-06	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKDMHDKC_01336	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKDMHDKC_01337	1.7e-188	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKDMHDKC_01338	1.83e-124	-	-	-	S	-	-	-	PAS domain
HKDMHDKC_01339	3.53e-314	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKDMHDKC_01340	1.16e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HKDMHDKC_01341	7.18e-145	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKDMHDKC_01342	5.38e-180	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HKDMHDKC_01343	1.2e-236	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HKDMHDKC_01344	6.36e-257	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HKDMHDKC_01345	1.43e-97	dkgB	-	-	S	-	-	-	reductase
HKDMHDKC_01346	3.26e-17	dkgB	-	-	S	-	-	-	reductase
HKDMHDKC_01347	1.46e-202	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKDMHDKC_01348	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKDMHDKC_01349	9.81e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKDMHDKC_01350	4.34e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HKDMHDKC_01351	3.39e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKDMHDKC_01352	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
HKDMHDKC_01353	1.38e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKDMHDKC_01354	7.83e-74	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HKDMHDKC_01355	1.84e-100	yybA	-	-	K	-	-	-	Transcriptional regulator
HKDMHDKC_01356	2.29e-125	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKDMHDKC_01357	1.27e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKDMHDKC_01358	1.59e-214	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HKDMHDKC_01359	8.18e-216	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKDMHDKC_01360	3.6e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDMHDKC_01361	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HKDMHDKC_01362	3.15e-175	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKDMHDKC_01363	3.24e-159	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKDMHDKC_01364	1.05e-229	-	-	-	-	-	-	-	-
HKDMHDKC_01365	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKDMHDKC_01366	1.73e-184	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HKDMHDKC_01367	6.43e-196	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKDMHDKC_01368	1.03e-138	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKDMHDKC_01369	3.29e-132	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKDMHDKC_01370	1.3e-301	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKDMHDKC_01372	1.51e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKDMHDKC_01373	1.23e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HKDMHDKC_01374	2.46e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HKDMHDKC_01375	4.26e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HKDMHDKC_01376	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKDMHDKC_01377	1.01e-311	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKDMHDKC_01378	5.91e-177	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HKDMHDKC_01379	6.26e-306	-	-	-	E	-	-	-	amino acid
HKDMHDKC_01380	3.99e-299	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKDMHDKC_01381	8e-245	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HKDMHDKC_01382	1.52e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HKDMHDKC_01383	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKDMHDKC_01384	8.43e-170	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HKDMHDKC_01385	1.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKDMHDKC_01386	2.82e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKDMHDKC_01387	1.19e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKDMHDKC_01388	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HKDMHDKC_01389	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDMHDKC_01390	1.59e-120	ymdB	-	-	S	-	-	-	Macro domain protein
HKDMHDKC_01391	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HKDMHDKC_01392	2.4e-160	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HKDMHDKC_01393	3.09e-286	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKDMHDKC_01394	2.49e-201	-	-	-	-	-	-	-	-
HKDMHDKC_01395	5.74e-71	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
HKDMHDKC_01396	4.62e-223	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HKDMHDKC_01397	9.8e-197	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKDMHDKC_01398	2.92e-183	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKDMHDKC_01399	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HKDMHDKC_01400	6.19e-208	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKDMHDKC_01401	4.68e-168	-	-	-	-	-	-	-	-
HKDMHDKC_01402	4.81e-69	-	-	-	-	-	-	-	-
HKDMHDKC_01403	3.01e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HKDMHDKC_01404	1.58e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKDMHDKC_01405	1.53e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HKDMHDKC_01406	8.8e-149	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HKDMHDKC_01407	9.98e-146	-	-	-	G	-	-	-	phosphoglycerate mutase
HKDMHDKC_01408	2.72e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKDMHDKC_01409	2.91e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKDMHDKC_01410	3.67e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_01411	5.09e-203	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKDMHDKC_01412	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKDMHDKC_01413	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKDMHDKC_01414	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKDMHDKC_01415	6.73e-51	-	-	-	-	-	-	-	-
HKDMHDKC_01416	6.92e-141	-	-	-	K	-	-	-	WHG domain
HKDMHDKC_01417	9.4e-128	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HKDMHDKC_01418	4.45e-128	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HKDMHDKC_01419	3.26e-254	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HKDMHDKC_01420	1.06e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKDMHDKC_01421	1.33e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKDMHDKC_01422	1.5e-123	cvpA	-	-	S	-	-	-	Colicin V production protein
HKDMHDKC_01423	8.33e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HKDMHDKC_01424	1.28e-197	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKDMHDKC_01425	7.1e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HKDMHDKC_01426	9.01e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKDMHDKC_01427	2.58e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HKDMHDKC_01428	9.37e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKDMHDKC_01429	3.82e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HKDMHDKC_01430	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_01431	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKDMHDKC_01432	2.39e-156	vanR	-	-	K	-	-	-	response regulator
HKDMHDKC_01433	1.85e-264	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HKDMHDKC_01434	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKDMHDKC_01435	1.29e-184	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HKDMHDKC_01436	9.23e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_01437	1.07e-282	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKDMHDKC_01438	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HKDMHDKC_01439	2.68e-174	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HKDMHDKC_01440	2.97e-213	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKDMHDKC_01441	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HKDMHDKC_01442	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKDMHDKC_01443	2.02e-179	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKDMHDKC_01444	4.8e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HKDMHDKC_01445	3.83e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKDMHDKC_01446	2.22e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKDMHDKC_01447	8.87e-174	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKDMHDKC_01448	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HKDMHDKC_01450	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HKDMHDKC_01451	1.04e-271	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKDMHDKC_01452	5.64e-54	-	-	-	-	-	-	-	-
HKDMHDKC_01453	9.18e-83	-	-	-	-	-	-	-	-
HKDMHDKC_01454	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKDMHDKC_01455	9.33e-179	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKDMHDKC_01456	1.1e-103	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKDMHDKC_01457	5.2e-54	-	-	-	-	-	-	-	-
HKDMHDKC_01458	3.75e-79	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKDMHDKC_01459	6.76e-106	-	-	-	-	-	-	-	-
HKDMHDKC_01460	3.52e-232	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKDMHDKC_01461	3.86e-107	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HKDMHDKC_01462	3.86e-143	-	-	-	-	-	-	-	-
HKDMHDKC_01463	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HKDMHDKC_01464	3.52e-58	-	-	-	-	-	-	-	-
HKDMHDKC_01465	5.01e-128	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HKDMHDKC_01467	3.06e-194	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HKDMHDKC_01468	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKDMHDKC_01469	2.85e-206	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKDMHDKC_01470	6.46e-137	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKDMHDKC_01471	5.92e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKDMHDKC_01472	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HKDMHDKC_01473	4.54e-210	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HKDMHDKC_01474	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKDMHDKC_01475	6.56e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKDMHDKC_01476	1.82e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKDMHDKC_01477	5.34e-218	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKDMHDKC_01478	8.85e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
HKDMHDKC_01479	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKDMHDKC_01480	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HKDMHDKC_01481	3.54e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKDMHDKC_01482	2.75e-244	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKDMHDKC_01483	1.25e-119	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HKDMHDKC_01484	1.94e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HKDMHDKC_01485	1.16e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKDMHDKC_01486	2.26e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HKDMHDKC_01487	1.78e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKDMHDKC_01488	1.45e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HKDMHDKC_01489	7.11e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKDMHDKC_01490	3.11e-169	csrR	-	-	K	-	-	-	response regulator
HKDMHDKC_01491	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKDMHDKC_01492	2.72e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKDMHDKC_01493	8.53e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HKDMHDKC_01494	6.34e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKDMHDKC_01495	1.01e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKDMHDKC_01496	9.43e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKDMHDKC_01497	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKDMHDKC_01498	1.11e-261	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKDMHDKC_01499	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKDMHDKC_01500	0.0	-	-	-	S	-	-	-	membrane
HKDMHDKC_01501	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKDMHDKC_01502	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKDMHDKC_01503	1.17e-119	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKDMHDKC_01504	9.32e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HKDMHDKC_01505	1.15e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HKDMHDKC_01506	1.47e-76	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HKDMHDKC_01507	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HKDMHDKC_01508	3.2e-214	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKDMHDKC_01509	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKDMHDKC_01510	1.34e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKDMHDKC_01511	6.93e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKDMHDKC_01513	5.22e-228	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKDMHDKC_01514	4.31e-278	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HKDMHDKC_01515	5.82e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HKDMHDKC_01516	2.41e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HKDMHDKC_01517	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKDMHDKC_01518	1.1e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HKDMHDKC_01519	6.36e-147	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HKDMHDKC_01520	4.08e-117	-	-	-	-	-	-	-	-
HKDMHDKC_01521	8.42e-102	-	-	-	-	-	-	-	-
HKDMHDKC_01522	4.69e-202	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HKDMHDKC_01523	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKDMHDKC_01524	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HKDMHDKC_01525	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKDMHDKC_01526	4.33e-36	-	-	-	-	-	-	-	-
HKDMHDKC_01527	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HKDMHDKC_01528	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKDMHDKC_01529	1e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKDMHDKC_01530	2.82e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKDMHDKC_01531	4.94e-209	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKDMHDKC_01532	2.2e-139	yjbH	-	-	Q	-	-	-	Thioredoxin
HKDMHDKC_01533	7.51e-145	-	-	-	S	-	-	-	CYTH
HKDMHDKC_01534	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKDMHDKC_01535	2.24e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKDMHDKC_01536	2.38e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKDMHDKC_01537	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HKDMHDKC_01538	5.46e-300	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKDMHDKC_01539	6.1e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HKDMHDKC_01540	1.88e-88	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKDMHDKC_01541	4.6e-271	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HKDMHDKC_01542	1.88e-135	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKDMHDKC_01543	8.29e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HKDMHDKC_01544	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKDMHDKC_01545	4.27e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HKDMHDKC_01546	2.58e-296	ymfH	-	-	S	-	-	-	Peptidase M16
HKDMHDKC_01547	3.01e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKDMHDKC_01548	1.85e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HKDMHDKC_01549	7.62e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKDMHDKC_01550	1.73e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKDMHDKC_01551	1.38e-312	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HKDMHDKC_01552	2.33e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HKDMHDKC_01553	1.39e-156	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HKDMHDKC_01554	2.75e-308	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HKDMHDKC_01555	1.29e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HKDMHDKC_01556	2.35e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKDMHDKC_01557	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKDMHDKC_01558	8.75e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKDMHDKC_01559	2.64e-49	-	-	-	-	-	-	-	-
HKDMHDKC_01560	6.07e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKDMHDKC_01561	6.19e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKDMHDKC_01562	2.67e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HKDMHDKC_01563	6.31e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKDMHDKC_01564	7.89e-26	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKDMHDKC_01565	1.45e-313	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HKDMHDKC_01566	1.53e-210	yvgN	-	-	C	-	-	-	Aldo keto reductase
HKDMHDKC_01568	7.35e-198	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKDMHDKC_01569	1.7e-122	-	-	-	K	-	-	-	acetyltransferase
HKDMHDKC_01570	1.85e-80	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HKDMHDKC_01571	1.83e-175	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HKDMHDKC_01572	4.59e-175	-	-	-	M	-	-	-	LysM domain protein
HKDMHDKC_01573	2.22e-159	-	-	-	M	-	-	-	LysM domain protein
HKDMHDKC_01575	7.78e-80	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HKDMHDKC_01576	3.9e-243	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKDMHDKC_01578	1.43e-187	-	-	-	K	-	-	-	SIS domain
HKDMHDKC_01579	1.53e-214	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HKDMHDKC_01582	1.44e-69	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
HKDMHDKC_01583	2.15e-246	-	-	-	-	-	-	-	-
HKDMHDKC_01584	6.31e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HKDMHDKC_01585	2.31e-87	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HKDMHDKC_01586	1.75e-182	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKDMHDKC_01587	4.33e-260	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKDMHDKC_01588	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKDMHDKC_01589	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKDMHDKC_01590	6.16e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKDMHDKC_01591	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKDMHDKC_01592	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HKDMHDKC_01593	1.29e-189	-	-	-	-	-	-	-	-
HKDMHDKC_01594	1.79e-292	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKDMHDKC_01595	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKDMHDKC_01596	7.2e-174	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HKDMHDKC_01597	8.17e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HKDMHDKC_01599	4.37e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKDMHDKC_01600	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HKDMHDKC_01601	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HKDMHDKC_01602	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKDMHDKC_01603	4.64e-265	camS	-	-	S	-	-	-	sex pheromone
HKDMHDKC_01604	1.29e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKDMHDKC_01605	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKDMHDKC_01606	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKDMHDKC_01607	1.86e-215	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HKDMHDKC_01609	1.51e-194	-	-	-	S	-	-	-	hydrolase
HKDMHDKC_01610	1.61e-49	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKDMHDKC_01611	7.5e-29	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKDMHDKC_01612	3.08e-164	-	-	-	L	-	-	-	Helix-turn-helix domain
HKDMHDKC_01613	5.03e-122	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
HKDMHDKC_01614	1.19e-113	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HKDMHDKC_01615	3.15e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HKDMHDKC_01616	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HKDMHDKC_01617	3.27e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKDMHDKC_01618	5.56e-183	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKDMHDKC_01619	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_01620	1.8e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HKDMHDKC_01621	5.54e-209	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HKDMHDKC_01622	2.12e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKDMHDKC_01623	3.41e-168	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_01624	6.34e-156	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HKDMHDKC_01625	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKDMHDKC_01626	2.11e-253	flp	-	-	V	-	-	-	Beta-lactamase
HKDMHDKC_01627	2.08e-196	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
HKDMHDKC_01628	1.11e-123	-	-	-	L	-	-	-	NUDIX domain
HKDMHDKC_01629	1.43e-87	-	-	-	-	-	-	-	-
HKDMHDKC_01630	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HKDMHDKC_01632	1.07e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKDMHDKC_01633	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKDMHDKC_01634	3.16e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HKDMHDKC_01635	5.64e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HKDMHDKC_01636	0.0	yhaN	-	-	L	-	-	-	AAA domain
HKDMHDKC_01637	1.3e-238	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKDMHDKC_01638	1.02e-201	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKDMHDKC_01639	2.42e-72	-	-	-	S	-	-	-	YtxH-like protein
HKDMHDKC_01640	4.48e-90	-	-	-	-	-	-	-	-
HKDMHDKC_01641	1.01e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HKDMHDKC_01642	1.55e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKDMHDKC_01643	3.63e-289	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKDMHDKC_01644	3.87e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKDMHDKC_01645	1.34e-53	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKDMHDKC_01646	3.11e-19	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HKDMHDKC_01647	4.28e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
HKDMHDKC_01648	6.18e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKDMHDKC_01649	8.28e-169	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HKDMHDKC_01650	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
HKDMHDKC_01651	2.92e-231	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HKDMHDKC_01652	8.76e-121	-	-	-	S	-	-	-	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
HKDMHDKC_01653	1.23e-249	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKDMHDKC_01654	7.5e-153	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HKDMHDKC_01655	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKDMHDKC_01656	5.98e-100	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HKDMHDKC_01657	1.92e-17	-	-	-	-	-	-	-	-
HKDMHDKC_01658	6.53e-90	-	-	-	K	-	-	-	Transcriptional regulator
HKDMHDKC_01659	4.61e-284	-	-	-	EGP	-	-	-	Major Facilitator
HKDMHDKC_01660	6.03e-292	dpaL	4.3.1.15	-	E	ko:K01751	-	ko00000,ko01000	Pyridoxal-phosphate dependent enzyme
HKDMHDKC_01661	8.5e-55	-	-	-	-	-	-	-	-
HKDMHDKC_01662	3.89e-112	-	-	-	-	-	-	-	-
HKDMHDKC_01663	1.99e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HKDMHDKC_01664	2.4e-207	repA	-	-	S	-	-	-	Replication initiator protein A
HKDMHDKC_01665	4.65e-184	-	-	-	D	-	-	-	AAA domain
HKDMHDKC_01666	5.78e-39	-	-	-	-	-	-	-	-
HKDMHDKC_01667	2.51e-109	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKDMHDKC_01668	1.32e-19	-	-	-	-	-	-	-	-
HKDMHDKC_01669	1.33e-77	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKDMHDKC_01670	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKDMHDKC_01671	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HKDMHDKC_01673	1.12e-241	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
HKDMHDKC_01677	1.1e-46	-	-	-	-	-	-	-	-
HKDMHDKC_01678	8.1e-44	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HKDMHDKC_01679	2.04e-117	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HKDMHDKC_01681	4.39e-18	-	-	-	-	-	-	-	-
HKDMHDKC_01682	1.23e-34	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HKDMHDKC_01683	9.73e-273	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HKDMHDKC_01684	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKDMHDKC_01685	5.23e-97	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HKDMHDKC_01686	5.17e-250	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKDMHDKC_01687	3.95e-95	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HKDMHDKC_01688	6.84e-124	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HKDMHDKC_01689	1.25e-169	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKDMHDKC_01690	4.88e-200	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKDMHDKC_01691	2.4e-191	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKDMHDKC_01692	9.93e-130	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HKDMHDKC_01694	1.5e-134	pncA	-	-	Q	-	-	-	Isochorismatase family
HKDMHDKC_01695	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKDMHDKC_01696	2.06e-169	-	-	-	F	-	-	-	NUDIX domain
HKDMHDKC_01697	1.19e-88	-	-	-	-	-	-	-	-
HKDMHDKC_01698	5.83e-69	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
HKDMHDKC_01700	6.79e-292	-	-	-	M	-	-	-	Cna protein B-type domain
HKDMHDKC_01701	7.33e-248	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKDMHDKC_01702	1.61e-57	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKDMHDKC_01703	3.09e-62	-	-	-	L	-	-	-	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKDMHDKC_01704	2e-103	-	-	-	-	-	-	-	-
HKDMHDKC_01705	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HKDMHDKC_01706	1.06e-31	-	-	-	-	-	-	-	-
HKDMHDKC_01707	6.11e-129	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HKDMHDKC_01708	0.0	-	-	-	S	-	-	-	TerB-C domain
HKDMHDKC_01709	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
HKDMHDKC_01710	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HKDMHDKC_01711	1.75e-296	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKDMHDKC_01712	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKDMHDKC_01713	1.41e-93	-	-	-	-	-	-	-	-
HKDMHDKC_01714	2.31e-281	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
HKDMHDKC_01715	3.53e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKDMHDKC_01716	3.15e-232	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKDMHDKC_01717	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKDMHDKC_01734	1.09e-79	-	-	-	-	-	-	-	-