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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HOFHCPNK_00003	2.39e-229	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HOFHCPNK_00004	1.77e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HOFHCPNK_00005	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HOFHCPNK_00006	1.66e-247	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HOFHCPNK_00007	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HOFHCPNK_00008	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HOFHCPNK_00009	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HOFHCPNK_00010	1.44e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HOFHCPNK_00011	3.19e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HOFHCPNK_00012	1.88e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HOFHCPNK_00013	8.24e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HOFHCPNK_00014	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOFHCPNK_00015	0.0	ycaM	-	-	E	-	-	-	amino acid
HOFHCPNK_00017	2.15e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HOFHCPNK_00018	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOFHCPNK_00019	1.42e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HOFHCPNK_00020	8.39e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOFHCPNK_00021	1.18e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOFHCPNK_00022	1.07e-39	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HOFHCPNK_00023	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HOFHCPNK_00024	7.24e-102	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HOFHCPNK_00025	1.38e-138	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HOFHCPNK_00027	1.8e-134	-	-	-	-	-	-	-	-
HOFHCPNK_00028	1.41e-120	-	-	-	-	-	-	-	-
HOFHCPNK_00029	3.3e-201	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HOFHCPNK_00030	7.98e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOFHCPNK_00031	1.82e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HOFHCPNK_00032	2.49e-110	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HOFHCPNK_00033	3.17e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HOFHCPNK_00034	3.45e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HOFHCPNK_00035	1.25e-264	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HOFHCPNK_00036	1.04e-180	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOFHCPNK_00037	5.35e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOFHCPNK_00038	1.71e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOFHCPNK_00039	1.29e-196	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HOFHCPNK_00040	1.55e-224	ybbR	-	-	S	-	-	-	YbbR-like protein
HOFHCPNK_00041	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOFHCPNK_00042	8.42e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HOFHCPNK_00043	2.49e-87	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOFHCPNK_00044	1.13e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOFHCPNK_00045	7.23e-242	-	-	-	S	-	-	-	Putative adhesin
HOFHCPNK_00046	5.95e-149	-	-	-	-	-	-	-	-
HOFHCPNK_00047	1.07e-192	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HOFHCPNK_00048	2.74e-210	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HOFHCPNK_00049	5.59e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HOFHCPNK_00050	1.11e-126	-	-	-	S	-	-	-	VanZ like family
HOFHCPNK_00051	2.13e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HOFHCPNK_00052	7.04e-230	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HOFHCPNK_00053	1.65e-226	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HOFHCPNK_00054	4.94e-54	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
HOFHCPNK_00055	1.45e-88	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HOFHCPNK_00057	3.17e-113	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HOFHCPNK_00058	1.48e-186	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HOFHCPNK_00059	2.51e-33	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HOFHCPNK_00060	5.13e-287	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOFHCPNK_00062	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HOFHCPNK_00063	8.38e-36	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HOFHCPNK_00064	4.11e-105	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HOFHCPNK_00065	1.62e-100	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HOFHCPNK_00066	7.57e-245	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HOFHCPNK_00067	9.78e-89	-	-	-	S	-	-	-	SdpI/YhfL protein family
HOFHCPNK_00068	6.61e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HOFHCPNK_00069	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HOFHCPNK_00070	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HOFHCPNK_00071	1.93e-139	vanZ	-	-	V	-	-	-	VanZ like family
HOFHCPNK_00072	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HOFHCPNK_00073	2.79e-108	-	-	-	EGP	-	-	-	Major Facilitator
HOFHCPNK_00074	6.39e-141	-	-	-	EGP	-	-	-	Major Facilitator
HOFHCPNK_00075	2.98e-94	-	-	-	-	-	-	-	-
HOFHCPNK_00078	2.07e-249	ampC	-	-	V	-	-	-	Beta-lactamase
HOFHCPNK_00079	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HOFHCPNK_00080	5.77e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HOFHCPNK_00081	1.27e-250	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOFHCPNK_00082	7.54e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HOFHCPNK_00083	9.87e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HOFHCPNK_00084	2.24e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOFHCPNK_00085	1.43e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HOFHCPNK_00086	9.31e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOFHCPNK_00087	1.96e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HOFHCPNK_00088	7.97e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOFHCPNK_00089	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HOFHCPNK_00090	2.1e-220	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOFHCPNK_00091	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOFHCPNK_00092	3.48e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HOFHCPNK_00093	3e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HOFHCPNK_00094	1.01e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HOFHCPNK_00095	2.97e-21	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HOFHCPNK_00096	6.72e-70	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HOFHCPNK_00097	3.08e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HOFHCPNK_00098	3.34e-287	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HOFHCPNK_00099	3.9e-106	uspA	-	-	T	-	-	-	universal stress protein
HOFHCPNK_00100	2.34e-08	-	-	-	-	-	-	-	-
HOFHCPNK_00101	3.11e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HOFHCPNK_00102	1.21e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HOFHCPNK_00103	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOFHCPNK_00105	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HOFHCPNK_00106	4.29e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HOFHCPNK_00107	2.67e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOFHCPNK_00108	7.16e-161	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HOFHCPNK_00109	4.76e-269	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
HOFHCPNK_00110	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HOFHCPNK_00111	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HOFHCPNK_00112	5.72e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HOFHCPNK_00113	1.56e-160	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HOFHCPNK_00114	5.06e-144	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HOFHCPNK_00115	2.19e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HOFHCPNK_00116	2.88e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HOFHCPNK_00117	9.8e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
HOFHCPNK_00118	1.66e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HOFHCPNK_00119	7.67e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HOFHCPNK_00120	1.33e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HOFHCPNK_00121	7.69e-226	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HOFHCPNK_00122	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HOFHCPNK_00123	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HOFHCPNK_00124	1.82e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOFHCPNK_00125	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOFHCPNK_00126	2.01e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOFHCPNK_00127	4.13e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HOFHCPNK_00128	2.81e-313	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HOFHCPNK_00129	7.39e-309	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOFHCPNK_00130	4.43e-95	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HOFHCPNK_00131	1.93e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HOFHCPNK_00132	3.41e-188	ylmH	-	-	S	-	-	-	S4 domain protein
HOFHCPNK_00133	2.05e-163	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HOFHCPNK_00134	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOFHCPNK_00135	3.24e-44	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HOFHCPNK_00136	3.65e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HOFHCPNK_00137	1.22e-23	-	-	-	-	-	-	-	-
HOFHCPNK_00138	1.68e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOFHCPNK_00139	4.29e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HOFHCPNK_00140	1.8e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HOFHCPNK_00141	3e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HOFHCPNK_00142	4.52e-161	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HOFHCPNK_00143	2.93e-150	-	-	-	S	-	-	-	repeat protein
HOFHCPNK_00144	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HOFHCPNK_00145	5.63e-226	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HOFHCPNK_00146	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOFHCPNK_00147	1.53e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HOFHCPNK_00148	2.39e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOFHCPNK_00149	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HOFHCPNK_00150	1.66e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HOFHCPNK_00151	7.67e-69	ylbG	-	-	S	-	-	-	UPF0298 protein
HOFHCPNK_00152	7.11e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HOFHCPNK_00153	5.77e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOFHCPNK_00154	1.45e-236	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HOFHCPNK_00155	5.23e-132	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HOFHCPNK_00156	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HOFHCPNK_00157	1.23e-229	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HOFHCPNK_00158	1.97e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HOFHCPNK_00159	1.44e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOFHCPNK_00160	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOFHCPNK_00161	2e-206	-	-	-	-	-	-	-	-
HOFHCPNK_00162	6.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOFHCPNK_00163	1.79e-278	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HOFHCPNK_00164	2.5e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOFHCPNK_00165	5.34e-134	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HOFHCPNK_00166	3.98e-116	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOFHCPNK_00167	1.29e-107	-	-	-	-	-	-	-	-
HOFHCPNK_00168	4.05e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HOFHCPNK_00169	6.2e-302	-	-	-	-	-	-	-	-
HOFHCPNK_00170	3.15e-158	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HOFHCPNK_00171	1.12e-212	-	-	-	-	-	-	-	-
HOFHCPNK_00172	2.58e-103	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HOFHCPNK_00173	5.1e-220	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HOFHCPNK_00174	5.62e-193	epsB	-	-	M	-	-	-	biosynthesis protein
HOFHCPNK_00175	3.3e-162	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HOFHCPNK_00176	5.69e-187	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HOFHCPNK_00177	2.06e-157	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HOFHCPNK_00178	1.21e-108	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HOFHCPNK_00179	2.18e-117	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HOFHCPNK_00180	3.49e-160	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HOFHCPNK_00181	5.28e-237	-	-	-	H	-	-	-	Glycosyl transferase family 11
HOFHCPNK_00182	4.29e-207	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HOFHCPNK_00183	6.33e-254	-	-	-	M	-	-	-	Glycosyl transferases group 1
HOFHCPNK_00184	5.88e-256	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HOFHCPNK_00185	7.35e-249	-	-	-	M	-	-	-	Glycosyl transferase family 2
HOFHCPNK_00186	1.08e-270	-	-	-	-	-	-	-	-
HOFHCPNK_00187	1.1e-281	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HOFHCPNK_00188	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HOFHCPNK_00189	4.11e-229	-	-	-	S	-	-	-	Acyltransferase family
HOFHCPNK_00190	7.2e-235	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOFHCPNK_00191	2.28e-31	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOFHCPNK_00192	5.27e-235	-	-	-	V	-	-	-	Abi-like protein
HOFHCPNK_00193	1.3e-286	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
HOFHCPNK_00194	5e-268	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOFHCPNK_00195	1.66e-214	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HOFHCPNK_00196	3.48e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HOFHCPNK_00197	1.53e-243	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HOFHCPNK_00198	1.33e-09	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HOFHCPNK_00199	1.33e-99	-	-	-	S	-	-	-	HIRAN
HOFHCPNK_00201	2.52e-210	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
HOFHCPNK_00202	1e-43	-	-	-	-	-	-	-	-
HOFHCPNK_00203	3.88e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HOFHCPNK_00204	1.14e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HOFHCPNK_00205	4.33e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HOFHCPNK_00206	1.53e-139	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOFHCPNK_00207	1.71e-206	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOFHCPNK_00208	5.46e-200	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HOFHCPNK_00209	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HOFHCPNK_00210	3.98e-79	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HOFHCPNK_00211	1.67e-222	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HOFHCPNK_00212	4.52e-128	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOFHCPNK_00213	4.24e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOFHCPNK_00214	4.14e-177	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HOFHCPNK_00215	1.82e-228	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HOFHCPNK_00216	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HOFHCPNK_00217	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HOFHCPNK_00218	2.29e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HOFHCPNK_00219	3.7e-155	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HOFHCPNK_00220	1.15e-195	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HOFHCPNK_00221	1.88e-313	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HOFHCPNK_00222	2.1e-78	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HOFHCPNK_00223	1.46e-160	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOFHCPNK_00224	6.56e-185	-	-	-	-	-	-	-	-
HOFHCPNK_00225	1.55e-140	-	-	-	-	-	-	-	-
HOFHCPNK_00226	1.45e-30	-	-	-	-	-	-	-	-
HOFHCPNK_00227	1.27e-134	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HOFHCPNK_00228	2.2e-171	-	-	-	-	-	-	-	-
HOFHCPNK_00229	8.88e-221	-	-	-	-	-	-	-	-
HOFHCPNK_00230	2.49e-297	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HOFHCPNK_00231	7.47e-70	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HOFHCPNK_00232	2.48e-215	-	-	-	S	-	-	-	DUF218 domain
HOFHCPNK_00233	4.51e-197	yxeH	-	-	S	-	-	-	hydrolase
HOFHCPNK_00234	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HOFHCPNK_00235	1.11e-153	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOFHCPNK_00236	2.49e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HOFHCPNK_00237	2.34e-217	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HOFHCPNK_00238	2.9e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HOFHCPNK_00239	6.42e-237	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HOFHCPNK_00240	3.11e-308	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HOFHCPNK_00241	2.26e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HOFHCPNK_00242	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HOFHCPNK_00243	4.14e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HOFHCPNK_00244	1.02e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
HOFHCPNK_00245	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HOFHCPNK_00246	1.11e-163	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HOFHCPNK_00247	6.34e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_00248	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HOFHCPNK_00249	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HOFHCPNK_00250	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HOFHCPNK_00251	5.21e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOFHCPNK_00252	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HOFHCPNK_00253	1.75e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HOFHCPNK_00254	9.14e-204	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HOFHCPNK_00255	8.2e-214	-	-	-	K	-	-	-	LysR substrate binding domain
HOFHCPNK_00256	0.0	-	-	-	C	-	-	-	FMN_bind
HOFHCPNK_00257	1.57e-152	-	-	-	C	-	-	-	nitroreductase
HOFHCPNK_00258	1.81e-38	-	-	-	-	-	-	-	-
HOFHCPNK_00259	1.42e-66	-	-	-	-	-	-	-	-
HOFHCPNK_00260	1.5e-56	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
HOFHCPNK_00261	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HOFHCPNK_00262	1.15e-179	-	-	-	-	-	-	-	-
HOFHCPNK_00263	2.05e-136	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HOFHCPNK_00265	8.4e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
HOFHCPNK_00266	2.21e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HOFHCPNK_00267	1.1e-181	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HOFHCPNK_00268	5.46e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
HOFHCPNK_00269	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HOFHCPNK_00270	1.01e-110	yfhC	-	-	C	-	-	-	nitroreductase
HOFHCPNK_00271	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HOFHCPNK_00272	2.39e-64	-	-	-	-	-	-	-	-
HOFHCPNK_00273	1.43e-48	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFHCPNK_00274	2.25e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFHCPNK_00275	7.8e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HOFHCPNK_00276	9.1e-65	-	-	-	S	-	-	-	MazG-like family
HOFHCPNK_00277	1.28e-82	-	-	-	-	-	-	-	-
HOFHCPNK_00278	1.39e-174	-	-	-	-	-	-	-	-
HOFHCPNK_00279	3.65e-54	-	-	-	-	-	-	-	-
HOFHCPNK_00280	4.3e-185	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HOFHCPNK_00281	1.76e-193	-	-	-	S	-	-	-	Fic/DOC family
HOFHCPNK_00282	6.11e-68	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
HOFHCPNK_00283	2.21e-57	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
HOFHCPNK_00284	1.1e-129	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HOFHCPNK_00285	4.43e-115	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HOFHCPNK_00286	1.45e-173	-	-	-	F	-	-	-	Phosphorylase superfamily
HOFHCPNK_00287	1.79e-110	-	-	-	S	-	-	-	ASCH
HOFHCPNK_00288	5.83e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HOFHCPNK_00289	2e-207	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HOFHCPNK_00290	4.73e-203	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HOFHCPNK_00291	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HOFHCPNK_00292	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HOFHCPNK_00293	2.24e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HOFHCPNK_00294	2.53e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HOFHCPNK_00295	1.67e-223	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HOFHCPNK_00296	1.8e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HOFHCPNK_00297	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HOFHCPNK_00298	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HOFHCPNK_00299	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HOFHCPNK_00300	5.37e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HOFHCPNK_00301	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HOFHCPNK_00302	2.06e-150	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HOFHCPNK_00303	6.69e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOFHCPNK_00304	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HOFHCPNK_00305	2.82e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HOFHCPNK_00306	2.28e-137	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HOFHCPNK_00307	1.37e-94	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HOFHCPNK_00308	1.61e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HOFHCPNK_00309	1.52e-305	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HOFHCPNK_00310	7.03e-224	degV1	-	-	S	-	-	-	DegV family
HOFHCPNK_00311	2.74e-77	-	-	-	-	-	-	-	-
HOFHCPNK_00312	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HOFHCPNK_00313	9.07e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOFHCPNK_00314	1.01e-220	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOFHCPNK_00315	4.62e-252	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HOFHCPNK_00316	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HOFHCPNK_00317	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HOFHCPNK_00318	5.72e-85	-	-	-	-	-	-	-	-
HOFHCPNK_00319	1.93e-209	-	-	-	S	-	-	-	EDD domain protein, DegV family
HOFHCPNK_00320	3.45e-197	-	-	-	-	-	-	-	-
HOFHCPNK_00321	2.76e-214	lysR	-	-	K	-	-	-	Transcriptional regulator
HOFHCPNK_00322	6.93e-261	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HOFHCPNK_00323	1.5e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HOFHCPNK_00324	6.77e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOFHCPNK_00325	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HOFHCPNK_00326	3.5e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HOFHCPNK_00327	2.92e-231	-	-	-	K	-	-	-	Transcriptional regulator
HOFHCPNK_00328	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOFHCPNK_00329	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOFHCPNK_00330	5.23e-151	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HOFHCPNK_00331	1.4e-148	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HOFHCPNK_00332	2.95e-160	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HOFHCPNK_00333	1.53e-213	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HOFHCPNK_00334	6.98e-94	-	-	-	C	-	-	-	Aldo/keto reductase family
HOFHCPNK_00335	3.31e-18	-	-	-	C	-	-	-	Aldo/keto reductase family
HOFHCPNK_00336	7.15e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HOFHCPNK_00337	6.34e-135	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HOFHCPNK_00338	2.63e-43	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HOFHCPNK_00339	1.43e-312	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HOFHCPNK_00340	1.46e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HOFHCPNK_00341	2.95e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFHCPNK_00342	5.33e-90	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
HOFHCPNK_00343	1.4e-99	-	-	-	K	-	-	-	Transcriptional regulator
HOFHCPNK_00344	2.69e-63	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HOFHCPNK_00345	7e-114	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HOFHCPNK_00346	2.34e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HOFHCPNK_00347	1.24e-144	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HOFHCPNK_00348	1.13e-125	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HOFHCPNK_00349	9.51e-47	-	-	-	C	-	-	-	Heavy-metal-associated domain
HOFHCPNK_00350	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HOFHCPNK_00351	2.06e-67	-	-	-	K	-	-	-	LytTr DNA-binding domain
HOFHCPNK_00352	5.89e-90	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HOFHCPNK_00353	9.67e-222	yobV3	-	-	K	-	-	-	WYL domain
HOFHCPNK_00354	4.3e-38	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HOFHCPNK_00355	5.09e-82	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HOFHCPNK_00356	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HOFHCPNK_00357	2.7e-43	-	-	-	G	ko:K03292	-	ko00000	Major facilitator Superfamily
HOFHCPNK_00358	2.78e-80	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HOFHCPNK_00359	8.01e-276	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HOFHCPNK_00360	6.65e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
HOFHCPNK_00361	4.43e-296	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF1100)
HOFHCPNK_00362	1.24e-129	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HOFHCPNK_00364	6.96e-201	-	-	-	C	-	-	-	Aldo keto reductase
HOFHCPNK_00365	5.26e-157	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HOFHCPNK_00366	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HOFHCPNK_00367	2.4e-41	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOFHCPNK_00368	4.45e-42	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HOFHCPNK_00369	1.41e-242	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HOFHCPNK_00370	3.13e-55	-	-	-	S	-	-	-	Cupin domain
HOFHCPNK_00371	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HOFHCPNK_00372	0.0	-	-	-	P	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
HOFHCPNK_00373	1.13e-98	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HOFHCPNK_00374	1.83e-15	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HOFHCPNK_00375	1.73e-294	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
HOFHCPNK_00376	2.79e-64	-	-	-	-	-	-	-	-
HOFHCPNK_00377	5.79e-90	-	-	-	K	-	-	-	HxlR family
HOFHCPNK_00378	9.19e-21	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
HOFHCPNK_00379	1.55e-17	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOFHCPNK_00380	8.75e-317	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HOFHCPNK_00381	7.35e-103	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HOFHCPNK_00382	2.64e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HOFHCPNK_00383	5.55e-143	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HOFHCPNK_00384	0.0	-	-	-	-	-	-	-	-
HOFHCPNK_00386	0.0	-	-	-	M	-	-	-	domain protein
HOFHCPNK_00387	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOFHCPNK_00389	0.0	-	-	-	S	-	-	-	domain, Protein
HOFHCPNK_00390	1.21e-144	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HOFHCPNK_00391	1.27e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HOFHCPNK_00392	3.18e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HOFHCPNK_00393	6.43e-127	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HOFHCPNK_00394	2.18e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HOFHCPNK_00395	3.29e-146	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_00396	2.08e-179	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HOFHCPNK_00397	5.57e-55	-	-	-	K	ko:K15773	-	ko00000,ko02048,ko03000	peptidyl-tyrosine sulfation
HOFHCPNK_00398	3.75e-57	-	-	-	-	-	-	-	-
HOFHCPNK_00399	6.05e-69	-	-	-	-	-	-	-	-
HOFHCPNK_00400	5.9e-94	-	-	-	K	-	-	-	Transcriptional regulator
HOFHCPNK_00401	1.09e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HOFHCPNK_00402	6.86e-92	-	-	-	-	-	-	-	-
HOFHCPNK_00404	1.17e-129	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HOFHCPNK_00405	1.19e-134	-	-	-	K	-	-	-	LysR substrate binding domain
HOFHCPNK_00406	3.03e-231	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HOFHCPNK_00407	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HOFHCPNK_00408	7.75e-115	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HOFHCPNK_00409	1.09e-221	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HOFHCPNK_00410	1.9e-316	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HOFHCPNK_00411	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOFHCPNK_00412	1.3e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HOFHCPNK_00413	7.68e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOFHCPNK_00414	4.91e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HOFHCPNK_00415	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HOFHCPNK_00416	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HOFHCPNK_00417	2.31e-196	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HOFHCPNK_00418	1.38e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HOFHCPNK_00419	1.66e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HOFHCPNK_00420	8.13e-207	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOFHCPNK_00421	3.51e-142	-	-	-	-	-	-	-	-
HOFHCPNK_00422	7.96e-135	-	-	-	-	-	-	-	-
HOFHCPNK_00423	0.0	-	-	-	C	-	-	-	FMN_bind
HOFHCPNK_00424	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HOFHCPNK_00425	0.0	-	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	EcoEI R protein C-terminal
HOFHCPNK_00426	5.39e-152	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HOFHCPNK_00427	2.91e-229	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HOFHCPNK_00428	2.86e-287	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HOFHCPNK_00429	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HOFHCPNK_00430	2.2e-195	-	-	-	-	-	-	-	-
HOFHCPNK_00431	0.0	-	-	-	KL	-	-	-	domain protein
HOFHCPNK_00432	1.27e-296	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HOFHCPNK_00433	7.91e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HOFHCPNK_00434	1.6e-306	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HOFHCPNK_00435	5.27e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HOFHCPNK_00436	1.03e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HOFHCPNK_00437	7.54e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HOFHCPNK_00438	1.39e-94	-	-	-	M	-	-	-	Lysin motif
HOFHCPNK_00439	8.87e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HOFHCPNK_00440	3.57e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HOFHCPNK_00441	5.22e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HOFHCPNK_00442	5.61e-82	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
HOFHCPNK_00443	1.17e-218	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HOFHCPNK_00444	1.65e-211	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HOFHCPNK_00445	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HOFHCPNK_00446	1.19e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HOFHCPNK_00448	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HOFHCPNK_00449	1.57e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HOFHCPNK_00450	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HOFHCPNK_00451	5.51e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HOFHCPNK_00452	1.1e-62	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HOFHCPNK_00453	5.02e-185	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOFHCPNK_00454	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HOFHCPNK_00455	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HOFHCPNK_00456	1.08e-305	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOFHCPNK_00457	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HOFHCPNK_00458	1.01e-222	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HOFHCPNK_00459	3.3e-137	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HOFHCPNK_00460	4.45e-150	-	-	-	GM	-	-	-	NmrA-like family
HOFHCPNK_00461	4.62e-316	yagE	-	-	E	-	-	-	amino acid
HOFHCPNK_00462	2.98e-140	-	-	-	S	-	-	-	Rib/alpha-like repeat
HOFHCPNK_00463	4.27e-85	-	-	-	S	-	-	-	Domain of unknown function DUF1828
HOFHCPNK_00464	2.11e-89	-	-	-	-	-	-	-	-
HOFHCPNK_00465	3.4e-58	-	-	-	-	-	-	-	-
HOFHCPNK_00466	1.22e-107	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HOFHCPNK_00467	3.8e-118	-	-	-	-	-	-	-	-
HOFHCPNK_00468	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HOFHCPNK_00469	4.28e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HOFHCPNK_00470	2.88e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOFHCPNK_00471	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOFHCPNK_00472	2.32e-86	-	-	-	-	-	-	-	-
HOFHCPNK_00473	4.27e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HOFHCPNK_00474	1.7e-113	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOFHCPNK_00475	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HOFHCPNK_00476	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HOFHCPNK_00477	4.36e-242	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HOFHCPNK_00478	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HOFHCPNK_00479	1.54e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HOFHCPNK_00480	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HOFHCPNK_00481	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HOFHCPNK_00482	2.57e-126	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOFHCPNK_00483	9.17e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOFHCPNK_00484	5.71e-201	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HOFHCPNK_00485	5.81e-125	-	-	-	L	-	-	-	nuclease
HOFHCPNK_00486	1.33e-194	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HOFHCPNK_00487	4.03e-64	-	-	-	K	-	-	-	Helix-turn-helix domain
HOFHCPNK_00488	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HOFHCPNK_00489	9.84e-41	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HOFHCPNK_00490	6.08e-312	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOFHCPNK_00491	5.12e-132	-	-	-	I	-	-	-	PAP2 superfamily
HOFHCPNK_00493	4.36e-204	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HOFHCPNK_00494	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HOFHCPNK_00495	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HOFHCPNK_00496	3.2e-126	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HOFHCPNK_00497	1.21e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOFHCPNK_00498	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOFHCPNK_00499	0.0	potE	-	-	E	-	-	-	Amino Acid
HOFHCPNK_00500	1.02e-124	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOFHCPNK_00501	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HOFHCPNK_00502	6.6e-159	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HOFHCPNK_00503	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOFHCPNK_00504	9.97e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOFHCPNK_00505	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HOFHCPNK_00506	9.65e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOFHCPNK_00507	4.59e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HOFHCPNK_00508	1.71e-155	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HOFHCPNK_00509	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HOFHCPNK_00510	4.29e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HOFHCPNK_00511	2.1e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOFHCPNK_00512	6.74e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOFHCPNK_00513	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOFHCPNK_00514	2.2e-62	-	-	-	J	-	-	-	ribosomal protein
HOFHCPNK_00515	2.17e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HOFHCPNK_00516	6.72e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HOFHCPNK_00517	2.25e-107	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HOFHCPNK_00518	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOFHCPNK_00519	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HOFHCPNK_00520	3.14e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HOFHCPNK_00521	3.37e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HOFHCPNK_00522	1.7e-175	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOFHCPNK_00523	2.87e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HOFHCPNK_00524	7.13e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HOFHCPNK_00525	4.15e-234	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOFHCPNK_00526	1.07e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HOFHCPNK_00527	1.87e-249	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HOFHCPNK_00528	3.62e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HOFHCPNK_00529	1.31e-286	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HOFHCPNK_00530	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOFHCPNK_00531	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOFHCPNK_00532	3.41e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HOFHCPNK_00533	9.78e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
HOFHCPNK_00534	3.88e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOFHCPNK_00535	1.35e-149	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HOFHCPNK_00536	1.68e-98	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
HOFHCPNK_00537	3.68e-151	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HOFHCPNK_00538	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HOFHCPNK_00539	3.13e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HOFHCPNK_00540	8.79e-125	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOFHCPNK_00541	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HOFHCPNK_00542	4.67e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOFHCPNK_00543	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HOFHCPNK_00544	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOFHCPNK_00545	1.78e-241	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOFHCPNK_00546	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HOFHCPNK_00547	5.24e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOFHCPNK_00548	3.29e-110	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HOFHCPNK_00549	2.49e-261	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HOFHCPNK_00550	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HOFHCPNK_00551	2.73e-209	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOFHCPNK_00552	3.16e-232	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOFHCPNK_00553	2.91e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HOFHCPNK_00554	4.35e-244	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HOFHCPNK_00555	6.2e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOFHCPNK_00556	1.01e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HOFHCPNK_00557	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HOFHCPNK_00558	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HOFHCPNK_00559	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HOFHCPNK_00560	9.04e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HOFHCPNK_00561	4.49e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HOFHCPNK_00562	1.11e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HOFHCPNK_00563	9.56e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HOFHCPNK_00564	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HOFHCPNK_00565	2.6e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HOFHCPNK_00566	1.55e-310	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HOFHCPNK_00567	8.3e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOFHCPNK_00568	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOFHCPNK_00569	1.63e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HOFHCPNK_00570	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HOFHCPNK_00571	8.55e-64	-	-	-	-	-	-	-	-
HOFHCPNK_00572	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HOFHCPNK_00573	1.85e-199	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HOFHCPNK_00574	1.71e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HOFHCPNK_00575	1.93e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOFHCPNK_00576	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOFHCPNK_00577	2.23e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOFHCPNK_00578	1.42e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOFHCPNK_00579	1.47e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HOFHCPNK_00580	6.05e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOFHCPNK_00581	1.56e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HOFHCPNK_00582	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HOFHCPNK_00583	1.67e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HOFHCPNK_00584	1.23e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HOFHCPNK_00585	1.89e-192	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOFHCPNK_00586	2.59e-313	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HOFHCPNK_00587	4.08e-18	-	-	-	-	-	-	-	-
HOFHCPNK_00588	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HOFHCPNK_00589	4.96e-121	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HOFHCPNK_00590	3.41e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HOFHCPNK_00591	1.59e-77	-	-	-	-	-	-	-	-
HOFHCPNK_00592	4.63e-74	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFHCPNK_00593	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HOFHCPNK_00594	2.31e-264	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOFHCPNK_00595	8.33e-225	-	-	-	I	-	-	-	Carboxylesterase family
HOFHCPNK_00596	1.12e-211	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HOFHCPNK_00597	7.29e-215	-	-	-	GK	-	-	-	ROK family
HOFHCPNK_00598	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HOFHCPNK_00599	6.93e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HOFHCPNK_00600	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HOFHCPNK_00601	4.6e-102	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HOFHCPNK_00602	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HOFHCPNK_00603	5.18e-128	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HOFHCPNK_00604	2.83e-165	pnb	-	-	C	-	-	-	nitroreductase
HOFHCPNK_00605	6.07e-14	-	-	-	-	-	-	-	-
HOFHCPNK_00606	3.38e-134	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HOFHCPNK_00612	4.62e-67	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
HOFHCPNK_00613	1.94e-241	-	-	-	S	-	-	-	Phage minor structural protein
HOFHCPNK_00614	9.36e-152	-	-	-	S	-	-	-	Phage tail protein
HOFHCPNK_00615	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HOFHCPNK_00621	1.47e-52	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HOFHCPNK_00622	2.92e-248	-	-	-	S	-	-	-	Phage capsid family
HOFHCPNK_00623	4.39e-144	-	-	-	S	-	-	-	Clp protease
HOFHCPNK_00624	1.91e-204	-	-	-	S	-	-	-	Phage portal protein
HOFHCPNK_00626	1.58e-305	-	-	-	S	-	-	-	Phage Terminase
HOFHCPNK_00627	2.31e-48	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HOFHCPNK_00628	3.76e-51	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HOFHCPNK_00629	2.09e-85	-	-	-	L	-	-	-	Phage terminase, small subunit
HOFHCPNK_00630	1.11e-112	-	-	-	S	-	-	-	HNH endonuclease
HOFHCPNK_00631	1.16e-102	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HOFHCPNK_00640	1.82e-32	-	-	-	-	-	-	-	-
HOFHCPNK_00641	9.73e-20	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HOFHCPNK_00646	1.84e-129	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HOFHCPNK_00649	1.71e-41	-	-	-	-	-	-	-	-
HOFHCPNK_00651	7.4e-23	-	-	-	-	-	-	-	-
HOFHCPNK_00654	2.81e-40	-	-	-	-	-	-	-	-
HOFHCPNK_00655	1.86e-133	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HOFHCPNK_00658	1.18e-25	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOFHCPNK_00659	1.15e-22	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOFHCPNK_00662	1.3e-91	-	-	-	K	-	-	-	Peptidase S24-like
HOFHCPNK_00664	8.78e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
HOFHCPNK_00666	2.19e-155	-	-	-	V	-	-	-	Abi-like protein
HOFHCPNK_00667	4.99e-48	-	-	-	-	-	-	-	-
HOFHCPNK_00668	5.91e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
HOFHCPNK_00670	5.65e-277	-	-	-	S	-	-	-	Phage integrase family
HOFHCPNK_00671	1.78e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HOFHCPNK_00672	6.22e-140	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HOFHCPNK_00673	2.46e-95	-	-	-	-	-	-	-	-
HOFHCPNK_00674	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOFHCPNK_00676	1.13e-158	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HOFHCPNK_00677	1.1e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HOFHCPNK_00678	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HOFHCPNK_00679	8.93e-90	-	-	-	-	-	-	-	-
HOFHCPNK_00680	2.75e-74	-	-	-	-	-	-	-	-
HOFHCPNK_00681	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HOFHCPNK_00682	3.86e-300	sptS	-	-	T	-	-	-	Histidine kinase
HOFHCPNK_00683	1.44e-149	dltr	-	-	K	-	-	-	response regulator
HOFHCPNK_00684	2.97e-149	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HOFHCPNK_00685	1.52e-28	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HOFHCPNK_00686	4.54e-91	-	-	-	O	-	-	-	OsmC-like protein
HOFHCPNK_00687	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HOFHCPNK_00688	1.02e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_00689	3.18e-199	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HOFHCPNK_00690	1.94e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HOFHCPNK_00691	6.47e-214	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HOFHCPNK_00692	2.09e-207	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HOFHCPNK_00693	4.75e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HOFHCPNK_00694	3.13e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HOFHCPNK_00695	1.64e-277	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HOFHCPNK_00698	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOFHCPNK_00699	1.35e-278	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HOFHCPNK_00700	3.55e-176	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HOFHCPNK_00701	2.29e-299	-	-	-	E	ko:K03294	-	ko00000	amino acid
HOFHCPNK_00702	1.22e-132	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HOFHCPNK_00703	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HOFHCPNK_00704	8.05e-171	-	-	-	-	-	-	-	-
HOFHCPNK_00705	1.24e-153	-	-	-	C	-	-	-	nitroreductase
HOFHCPNK_00706	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HOFHCPNK_00707	3.92e-178	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HOFHCPNK_00708	7.47e-70	-	-	-	S	-	-	-	Enterocin A Immunity
HOFHCPNK_00709	2.4e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HOFHCPNK_00710	5.75e-224	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HOFHCPNK_00711	8.05e-166	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HOFHCPNK_00712	1.58e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOFHCPNK_00714	1.15e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HOFHCPNK_00715	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HOFHCPNK_00716	4.1e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HOFHCPNK_00717	2.13e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOFHCPNK_00718	3.84e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOFHCPNK_00719	2.05e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HOFHCPNK_00720	1.24e-216	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HOFHCPNK_00721	2.89e-206	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HOFHCPNK_00722	2.8e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFHCPNK_00723	2.68e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_00724	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HOFHCPNK_00725	1.36e-207	-	-	-	S	-	-	-	Phospholipase, patatin family
HOFHCPNK_00726	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HOFHCPNK_00727	7.42e-75	-	-	-	S	-	-	-	Enterocin A Immunity
HOFHCPNK_00729	9.4e-100	-	-	-	EGP	-	-	-	Major facilitator superfamily
HOFHCPNK_00730	9.09e-204	-	-	-	EGP	-	-	-	Major facilitator superfamily
HOFHCPNK_00731	9.28e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HOFHCPNK_00732	1.16e-128	-	-	-	S	-	-	-	Putative adhesin
HOFHCPNK_00733	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOFHCPNK_00734	3.51e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HOFHCPNK_00735	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HOFHCPNK_00736	1.77e-199	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HOFHCPNK_00737	7.95e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOFHCPNK_00738	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOFHCPNK_00739	1.18e-191	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOFHCPNK_00740	4.37e-176	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_00741	6.61e-190	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOFHCPNK_00742	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HOFHCPNK_00743	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_00744	2.27e-98	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HOFHCPNK_00745	2.6e-202	-	-	-	S	-	-	-	Alpha beta hydrolase
HOFHCPNK_00746	2.81e-265	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HOFHCPNK_00747	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HOFHCPNK_00748	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Glycosyl hydrolases family 31
HOFHCPNK_00749	5.45e-232	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HOFHCPNK_00750	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HOFHCPNK_00751	2.38e-94	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HOFHCPNK_00752	1.49e-194	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HOFHCPNK_00753	1.4e-155	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HOFHCPNK_00754	5.16e-115	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HOFHCPNK_00756	5.75e-267	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HOFHCPNK_00757	1.64e-108	-	-	-	-	-	-	-	-
HOFHCPNK_00758	4.11e-95	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOFHCPNK_00759	7.95e-45	-	-	-	-	-	-	-	-
HOFHCPNK_00760	2.3e-276	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HOFHCPNK_00761	1.23e-144	-	-	-	I	-	-	-	Acid phosphatase homologues
HOFHCPNK_00762	1.08e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HOFHCPNK_00763	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HOFHCPNK_00764	0.0	-	-	-	C	-	-	-	FMN_bind
HOFHCPNK_00765	1.31e-211	-	-	-	K	-	-	-	LysR family
HOFHCPNK_00766	3.04e-258	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HOFHCPNK_00767	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOFHCPNK_00768	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HOFHCPNK_00769	6.12e-76	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HOFHCPNK_00770	1.19e-195	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	CAT RNA binding domain
HOFHCPNK_00771	3.59e-52	-	-	-	-	-	-	-	-
HOFHCPNK_00772	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HOFHCPNK_00773	6.32e-68	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HOFHCPNK_00774	1.71e-111	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HOFHCPNK_00775	5.07e-166	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
HOFHCPNK_00776	2.86e-137	-	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HOFHCPNK_00777	9.37e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
HOFHCPNK_00778	2.29e-176	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HOFHCPNK_00779	2.57e-307	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HOFHCPNK_00780	2.78e-79	-	-	-	K	-	-	-	Transcriptional regulator
HOFHCPNK_00781	1.44e-98	-	-	-	K	-	-	-	Transcriptional regulator
HOFHCPNK_00782	1.99e-193	-	-	-	S	-	-	-	hydrolase
HOFHCPNK_00783	4.86e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1440)
HOFHCPNK_00784	1.57e-187	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HOFHCPNK_00785	4.48e-102	-	-	-	K	-	-	-	acetyltransferase
HOFHCPNK_00786	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HOFHCPNK_00787	5.51e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOFHCPNK_00788	8.38e-126	qacA	-	-	EGP	-	-	-	Major Facilitator
HOFHCPNK_00789	9.29e-182	qacA	-	-	EGP	-	-	-	Major Facilitator
HOFHCPNK_00790	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HOFHCPNK_00791	5.44e-187	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HOFHCPNK_00792	4.43e-177	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
HOFHCPNK_00793	3.31e-212	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HOFHCPNK_00794	4.71e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HOFHCPNK_00795	8.55e-247	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HOFHCPNK_00796	2.16e-108	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HOFHCPNK_00797	9.45e-145	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HOFHCPNK_00798	3.72e-166	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
HOFHCPNK_00799	3.04e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HOFHCPNK_00801	3.38e-76	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HOFHCPNK_00802	4.65e-100	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HOFHCPNK_00803	4.75e-67	-	-	-	-	-	-	-	-
HOFHCPNK_00804	3.12e-220	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HOFHCPNK_00805	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HOFHCPNK_00806	5.83e-222	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HOFHCPNK_00807	1.96e-161	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HOFHCPNK_00808	1.32e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOFHCPNK_00809	2.27e-164	-	-	-	-	-	-	-	-
HOFHCPNK_00810	1.82e-278	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HOFHCPNK_00811	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HOFHCPNK_00812	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HOFHCPNK_00813	1.7e-164	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HOFHCPNK_00814	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HOFHCPNK_00815	3.1e-276	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOFHCPNK_00821	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HOFHCPNK_00822	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
HOFHCPNK_00823	1.76e-199	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOFHCPNK_00824	4.61e-308	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOFHCPNK_00825	7.34e-54	-	-	-	-	-	-	-	-
HOFHCPNK_00826	1.52e-274	-	-	-	E	-	-	-	Major Facilitator Superfamily
HOFHCPNK_00827	2.47e-223	pbpX2	-	-	V	-	-	-	Beta-lactamase
HOFHCPNK_00828	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HOFHCPNK_00829	3.63e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOFHCPNK_00830	9.88e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HOFHCPNK_00831	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOFHCPNK_00832	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HOFHCPNK_00833	4.82e-60	-	-	-	-	-	-	-	-
HOFHCPNK_00834	5.68e-260	-	-	-	S	-	-	-	Membrane
HOFHCPNK_00835	7.91e-78	-	-	-	-	-	-	-	-
HOFHCPNK_00836	8.97e-66	-	-	-	-	-	-	-	-
HOFHCPNK_00837	9.94e-60	-	-	-	-	-	-	-	-
HOFHCPNK_00839	2.47e-112	ykuL	-	-	S	-	-	-	(CBS) domain
HOFHCPNK_00840	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HOFHCPNK_00841	1.39e-257	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HOFHCPNK_00843	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HOFHCPNK_00844	1.24e-204	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOFHCPNK_00845	3.3e-36	-	-	-	-	-	-	-	-
HOFHCPNK_00846	8.28e-47	-	-	-	-	-	-	-	-
HOFHCPNK_00847	1.03e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HOFHCPNK_00848	1.75e-202	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
HOFHCPNK_00849	3.9e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
HOFHCPNK_00850	1.66e-303	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HOFHCPNK_00851	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HOFHCPNK_00852	8.25e-63	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HOFHCPNK_00853	8.24e-137	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HOFHCPNK_00854	7.17e-258	-	-	-	S	-	-	-	DUF218 domain
HOFHCPNK_00855	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_00856	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HOFHCPNK_00857	1.05e-231	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HOFHCPNK_00858	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HOFHCPNK_00859	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HOFHCPNK_00860	6.33e-226	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HOFHCPNK_00861	4.97e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOFHCPNK_00862	2.01e-214	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HOFHCPNK_00863	2.8e-256	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HOFHCPNK_00864	8.85e-226	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HOFHCPNK_00865	9.29e-250	-	-	-	V	-	-	-	Beta-lactamase
HOFHCPNK_00866	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOFHCPNK_00867	1.05e-203	gspK	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HOFHCPNK_00868	1.04e-270	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HOFHCPNK_00869	1.84e-196	-	-	-	S	-	-	-	Putative esterase
HOFHCPNK_00870	1.13e-249	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HOFHCPNK_00871	1.05e-171	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HOFHCPNK_00872	9.42e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HOFHCPNK_00873	9.68e-173	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HOFHCPNK_00874	7.88e-24	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HOFHCPNK_00875	2.53e-206	-	-	-	S	-	-	-	Aldo/keto reductase family
HOFHCPNK_00876	1.26e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HOFHCPNK_00877	8.74e-155	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HOFHCPNK_00878	4.15e-162	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HOFHCPNK_00879	1.45e-303	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HOFHCPNK_00880	6.61e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HOFHCPNK_00882	1.78e-162	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOFHCPNK_00883	5.76e-296	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HOFHCPNK_00884	1.58e-60	-	-	-	I	-	-	-	bis(5'-adenosyl)-triphosphatase activity
HOFHCPNK_00885	7.1e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HOFHCPNK_00886	8.45e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HOFHCPNK_00887	1.37e-116	-	-	-	-	-	-	-	-
HOFHCPNK_00888	2.26e-117	-	-	-	-	-	-	-	-
HOFHCPNK_00889	3.09e-102	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HOFHCPNK_00890	4.35e-86	-	-	-	S	-	-	-	Cupredoxin-like domain
HOFHCPNK_00891	6.31e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HOFHCPNK_00892	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HOFHCPNK_00893	3.17e-200	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HOFHCPNK_00894	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HOFHCPNK_00895	0.0	-	-	-	E	-	-	-	Amino acid permease
HOFHCPNK_00896	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HOFHCPNK_00897	1.67e-315	ynbB	-	-	P	-	-	-	aluminum resistance
HOFHCPNK_00898	1.13e-98	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFHCPNK_00899	2.63e-296	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HOFHCPNK_00900	7.94e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HOFHCPNK_00901	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HOFHCPNK_00902	1.98e-149	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HOFHCPNK_00903	9.66e-138	-	-	-	-	-	-	-	-
HOFHCPNK_00904	1.27e-195	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
HOFHCPNK_00905	7.78e-267	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HOFHCPNK_00906	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HOFHCPNK_00907	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOFHCPNK_00908	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HOFHCPNK_00909	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HOFHCPNK_00910	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HOFHCPNK_00911	1.7e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOFHCPNK_00912	3.62e-79	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HOFHCPNK_00913	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HOFHCPNK_00914	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOFHCPNK_00915	2.08e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOFHCPNK_00916	1.04e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HOFHCPNK_00917	4.56e-266	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOFHCPNK_00918	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFHCPNK_00919	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFHCPNK_00920	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HOFHCPNK_00921	7.47e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HOFHCPNK_00922	2.5e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOFHCPNK_00923	1.12e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HOFHCPNK_00924	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HOFHCPNK_00925	8.13e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HOFHCPNK_00926	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HOFHCPNK_00927	2.56e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HOFHCPNK_00928	1.19e-280	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HOFHCPNK_00929	0.0	-	-	-	-	-	-	-	-
HOFHCPNK_00930	2.64e-151	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HOFHCPNK_00932	6.94e-146	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HOFHCPNK_00933	7.49e-29	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HOFHCPNK_00934	4.18e-118	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
HOFHCPNK_00935	1.39e-256	ydhF	-	-	S	-	-	-	Aldo keto reductase
HOFHCPNK_00937	5.09e-285	-	-	-	S	-	-	-	Sterol carrier protein domain
HOFHCPNK_00938	6.39e-150	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HOFHCPNK_00939	2.7e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HOFHCPNK_00940	3.71e-177	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HOFHCPNK_00941	4.34e-198	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HOFHCPNK_00942	1.92e-26	-	-	-	-	-	-	-	-
HOFHCPNK_00943	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HOFHCPNK_00944	1.72e-214	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HOFHCPNK_00945	3.18e-19	-	-	-	S	-	-	-	CsbD-like
HOFHCPNK_00946	1.29e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
HOFHCPNK_00947	9.2e-207	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HOFHCPNK_00948	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HOFHCPNK_00949	4.93e-212	-	-	-	S	-	-	-	Alpha beta hydrolase
HOFHCPNK_00950	3.66e-54	-	-	-	-	-	-	-	-
HOFHCPNK_00951	2.88e-229	ydbI	-	-	K	-	-	-	AI-2E family transporter
HOFHCPNK_00952	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HOFHCPNK_00953	2.28e-271	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HOFHCPNK_00954	1.8e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HOFHCPNK_00955	1.71e-246	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOFHCPNK_00956	0.0	-	-	-	S	-	-	-	domain, Protein
HOFHCPNK_00957	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOFHCPNK_00958	0.0	-	-	-	M	-	-	-	domain protein
HOFHCPNK_00959	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HOFHCPNK_00960	1.37e-220	-	-	-	K	-	-	-	LysR substrate binding domain
HOFHCPNK_00961	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HOFHCPNK_00962	1.55e-309	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HOFHCPNK_00963	1.1e-170	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HOFHCPNK_00964	4.14e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HOFHCPNK_00965	1.18e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HOFHCPNK_00966	1.24e-192	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HOFHCPNK_00967	1.33e-19	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HOFHCPNK_00968	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOFHCPNK_00969	2.13e-75	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOFHCPNK_00970	2.48e-166	-	-	-	P	-	-	-	Major Facilitator Superfamily
HOFHCPNK_00971	1.42e-211	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HOFHCPNK_00972	2.51e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
HOFHCPNK_00973	3.05e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
HOFHCPNK_00974	9.16e-202	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HOFHCPNK_00975	7.51e-194	-	-	-	I	-	-	-	Acyl-transferase
HOFHCPNK_00978	3.03e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HOFHCPNK_00979	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HOFHCPNK_00980	0.0	yycH	-	-	S	-	-	-	YycH protein
HOFHCPNK_00981	6.61e-190	yycI	-	-	S	-	-	-	YycH protein
HOFHCPNK_00982	6.41e-193	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HOFHCPNK_00983	1.04e-263	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HOFHCPNK_00984	3.66e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOFHCPNK_00985	2.2e-142	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HOFHCPNK_00986	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_00987	3.01e-124	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HOFHCPNK_00988	3.49e-219	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HOFHCPNK_00989	5.77e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HOFHCPNK_00990	7.65e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HOFHCPNK_00991	4.66e-240	ysdE	-	-	P	-	-	-	Citrate transporter
HOFHCPNK_00992	6.45e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HOFHCPNK_00993	1.14e-23	-	-	-	-	-	-	-	-
HOFHCPNK_00994	1.57e-199	-	-	-	-	-	-	-	-
HOFHCPNK_00996	4.47e-313	-	-	-	M	-	-	-	Glycosyl transferase
HOFHCPNK_00997	1.09e-272	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HOFHCPNK_00998	2.61e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HOFHCPNK_00999	2.73e-208	-	-	-	L	-	-	-	HNH nucleases
HOFHCPNK_01000	7.38e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_01001	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOFHCPNK_01002	3.97e-136	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HOFHCPNK_01003	5.23e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HOFHCPNK_01004	2.16e-168	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HOFHCPNK_01005	5.26e-123	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HOFHCPNK_01006	1.63e-172	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HOFHCPNK_01007	1.33e-104	-	-	-	-	-	-	-	-
HOFHCPNK_01008	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOFHCPNK_01009	1.81e-159	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HOFHCPNK_01010	2.39e-225	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOFHCPNK_01011	3.86e-187	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOFHCPNK_01012	4.75e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HOFHCPNK_01013	1.58e-203	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HOFHCPNK_01014	5.7e-160	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HOFHCPNK_01015	9.68e-83	-	-	-	-	-	-	-	-
HOFHCPNK_01016	7.71e-231	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOFHCPNK_01017	8.76e-283	-	-	-	S	-	-	-	CAAX protease self-immunity
HOFHCPNK_01018	4.1e-307	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HOFHCPNK_01019	4.09e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOFHCPNK_01020	8.47e-180	-	-	-	-	-	-	-	-
HOFHCPNK_01021	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HOFHCPNK_01022	6.59e-265	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HOFHCPNK_01023	1.03e-151	-	-	-	-	-	-	-	-
HOFHCPNK_01024	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HOFHCPNK_01025	1.02e-239	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HOFHCPNK_01026	1.61e-155	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HOFHCPNK_01027	6.44e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOFHCPNK_01028	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HOFHCPNK_01029	2.04e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HOFHCPNK_01030	5.87e-276	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
HOFHCPNK_01031	2.64e-291	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HOFHCPNK_01032	5.59e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HOFHCPNK_01033	1.87e-196	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HOFHCPNK_01034	2.13e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HOFHCPNK_01035	1.6e-89	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HOFHCPNK_01036	3.49e-23	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HOFHCPNK_01037	8.35e-277	-	-	-	S	-	-	-	zinc-ribbon domain
HOFHCPNK_01038	4.51e-17	-	-	-	-	-	-	-	-
HOFHCPNK_01039	5.62e-216	-	-	-	-	-	-	-	-
HOFHCPNK_01040	3.82e-114	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HOFHCPNK_01041	1.89e-129	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HOFHCPNK_01042	4.26e-171	-	-	-	K	-	-	-	UTRA domain
HOFHCPNK_01043	3.05e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HOFHCPNK_01044	4.96e-113	usp5	-	-	T	-	-	-	universal stress protein
HOFHCPNK_01046	9.6e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HOFHCPNK_01047	2.58e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HOFHCPNK_01048	2.46e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOFHCPNK_01049	8.69e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOFHCPNK_01050	6.97e-107	-	-	-	-	-	-	-	-
HOFHCPNK_01051	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HOFHCPNK_01052	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HOFHCPNK_01053	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HOFHCPNK_01054	2.3e-83	-	-	-	-	-	-	-	-
HOFHCPNK_01055	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HOFHCPNK_01056	8.75e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOFHCPNK_01057	1.83e-134	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HOFHCPNK_01058	4.42e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HOFHCPNK_01059	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOFHCPNK_01060	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOFHCPNK_01061	2.19e-290	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOFHCPNK_01062	9.39e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
HOFHCPNK_01063	0.0	-	-	-	D	-	-	-	transport
HOFHCPNK_01064	9.83e-175	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HOFHCPNK_01065	6.42e-210	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HOFHCPNK_01066	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HOFHCPNK_01067	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HOFHCPNK_01068	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HOFHCPNK_01069	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HOFHCPNK_01070	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HOFHCPNK_01071	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HOFHCPNK_01072	1.06e-95	-	-	-	-	-	-	-	-
HOFHCPNK_01073	1.47e-162	-	-	-	-	-	-	-	-
HOFHCPNK_01074	1.75e-39	-	-	-	-	-	-	-	-
HOFHCPNK_01075	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HOFHCPNK_01076	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HOFHCPNK_01077	0.0	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HOFHCPNK_01078	2.55e-185	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HOFHCPNK_01079	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HOFHCPNK_01080	6.12e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HOFHCPNK_01081	2.11e-175	-	-	-	-	-	-	-	-
HOFHCPNK_01082	3.41e-193	-	-	-	-	-	-	-	-
HOFHCPNK_01083	2.22e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HOFHCPNK_01084	1.11e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOFHCPNK_01085	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOFHCPNK_01086	5.36e-92	-	-	-	S	-	-	-	GtrA-like protein
HOFHCPNK_01087	1.56e-227	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HOFHCPNK_01088	7.1e-152	-	-	-	-	-	-	-	-
HOFHCPNK_01089	2.21e-195	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HOFHCPNK_01090	4.25e-219	-	-	-	G	-	-	-	Aldose 1-epimerase
HOFHCPNK_01091	3.28e-260	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HOFHCPNK_01092	1.13e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HOFHCPNK_01093	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HOFHCPNK_01094	9.21e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOFHCPNK_01096	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HOFHCPNK_01097	2.24e-160	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOFHCPNK_01098	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HOFHCPNK_01099	8.46e-81	-	-	-	-	-	-	-	-
HOFHCPNK_01100	4.87e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOFHCPNK_01101	1.47e-100	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HOFHCPNK_01102	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOFHCPNK_01103	2.08e-105	-	-	-	-	-	-	-	-
HOFHCPNK_01104	1.29e-315	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOFHCPNK_01105	3.99e-166	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HOFHCPNK_01106	2.83e-57	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HOFHCPNK_01107	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOFHCPNK_01108	1.1e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HOFHCPNK_01109	1.76e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HOFHCPNK_01110	2.42e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HOFHCPNK_01111	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOFHCPNK_01112	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOFHCPNK_01113	3.8e-202	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HOFHCPNK_01114	2.21e-148	-	-	-	-	-	-	-	-
HOFHCPNK_01116	2.85e-147	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
HOFHCPNK_01117	4.06e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HOFHCPNK_01118	6.82e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HOFHCPNK_01119	1.52e-129	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HOFHCPNK_01120	1.44e-114	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HOFHCPNK_01121	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOFHCPNK_01122	2.07e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HOFHCPNK_01123	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HOFHCPNK_01124	3.56e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HOFHCPNK_01125	2.99e-49	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HOFHCPNK_01126	7.77e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HOFHCPNK_01127	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOFHCPNK_01128	9.21e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOFHCPNK_01129	1.05e-227	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HOFHCPNK_01130	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HOFHCPNK_01131	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HOFHCPNK_01132	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HOFHCPNK_01133	6.6e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HOFHCPNK_01134	5.55e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HOFHCPNK_01135	1.58e-293	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOFHCPNK_01136	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOFHCPNK_01137	2.93e-199	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOFHCPNK_01138	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HOFHCPNK_01139	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOFHCPNK_01140	4.73e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HOFHCPNK_01141	3.78e-92	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HOFHCPNK_01142	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HOFHCPNK_01143	6.24e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOFHCPNK_01144	4.58e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HOFHCPNK_01145	1.66e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HOFHCPNK_01146	1.59e-172	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HOFHCPNK_01147	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HOFHCPNK_01149	5.2e-229	-	-	-	K	-	-	-	Helix-turn-helix
HOFHCPNK_01150	7.98e-50	-	-	-	-	-	-	-	-
HOFHCPNK_01151	9.94e-90	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HOFHCPNK_01152	1.63e-121	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOFHCPNK_01153	6.29e-146	-	-	-	S	-	-	-	Flavodoxin-like fold
HOFHCPNK_01154	7.78e-63	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HOFHCPNK_01156	9.45e-67	-	-	-	-	-	-	-	-
HOFHCPNK_01157	5.66e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HOFHCPNK_01158	3.72e-86	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HOFHCPNK_01159	2.08e-127	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HOFHCPNK_01160	1.97e-123	-	-	-	-	-	-	-	-
HOFHCPNK_01161	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HOFHCPNK_01162	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HOFHCPNK_01163	9.92e-266	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HOFHCPNK_01164	1.64e-52	-	-	-	-	-	-	-	-
HOFHCPNK_01165	4.86e-28	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOFHCPNK_01166	4.68e-238	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOFHCPNK_01167	1.67e-101	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HOFHCPNK_01168	4.92e-104	-	-	-	-	-	-	-	-
HOFHCPNK_01170	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOFHCPNK_01171	2.21e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOFHCPNK_01172	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HOFHCPNK_01173	5.27e-241	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HOFHCPNK_01174	1.2e-182	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HOFHCPNK_01175	1.55e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_01176	0.0	-	-	-	E	-	-	-	amino acid
HOFHCPNK_01177	1.28e-54	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HOFHCPNK_01178	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOFHCPNK_01179	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HOFHCPNK_01180	3.03e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HOFHCPNK_01181	1.69e-278	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOFHCPNK_01182	5.46e-161	-	-	-	S	-	-	-	(CBS) domain
HOFHCPNK_01183	2.31e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HOFHCPNK_01184	2.68e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HOFHCPNK_01185	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOFHCPNK_01186	8.68e-47	yabO	-	-	J	-	-	-	S4 domain protein
HOFHCPNK_01187	5.29e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HOFHCPNK_01188	3.27e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
HOFHCPNK_01189	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HOFHCPNK_01190	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOFHCPNK_01191	0.0	-	-	-	S	-	-	-	membrane
HOFHCPNK_01192	1.66e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HOFHCPNK_01193	1.36e-245	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOFHCPNK_01194	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HOFHCPNK_01197	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HOFHCPNK_01198	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFHCPNK_01199	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFHCPNK_01200	1.28e-154	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HOFHCPNK_01201	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOFHCPNK_01202	1.14e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HOFHCPNK_01203	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOFHCPNK_01204	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HOFHCPNK_01205	5.06e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOFHCPNK_01206	3.16e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HOFHCPNK_01207	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HOFHCPNK_01208	4.88e-199	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOFHCPNK_01209	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOFHCPNK_01210	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOFHCPNK_01211	7.46e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOFHCPNK_01212	4.26e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOFHCPNK_01213	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HOFHCPNK_01214	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOFHCPNK_01215	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOFHCPNK_01216	1.67e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOFHCPNK_01217	4.3e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOFHCPNK_01218	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOFHCPNK_01219	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOFHCPNK_01220	6.14e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOFHCPNK_01221	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOFHCPNK_01222	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOFHCPNK_01223	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HOFHCPNK_01224	8.21e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HOFHCPNK_01225	2.42e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HOFHCPNK_01226	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HOFHCPNK_01227	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOFHCPNK_01228	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HOFHCPNK_01229	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOFHCPNK_01230	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOFHCPNK_01231	2.19e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFHCPNK_01232	3.85e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HOFHCPNK_01233	1.1e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOFHCPNK_01234	1.86e-208	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOFHCPNK_01235	2.19e-180	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOFHCPNK_01236	8.78e-195	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HOFHCPNK_01237	7.82e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOFHCPNK_01238	7.96e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HOFHCPNK_01239	1.8e-104	-	-	-	-	-	-	-	-
HOFHCPNK_01240	5.1e-206	-	-	-	GM	-	-	-	NmrA-like family
HOFHCPNK_01241	1.27e-141	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HOFHCPNK_01242	1.83e-165	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HOFHCPNK_01243	5.56e-70	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HOFHCPNK_01244	5.88e-199	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HOFHCPNK_01245	2.66e-56	-	-	-	-	-	-	-	-
HOFHCPNK_01246	1.33e-35	-	-	-	-	-	-	-	-
HOFHCPNK_01247	5.21e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOFHCPNK_01248	1.2e-236	-	-	-	S	-	-	-	AAA domain
HOFHCPNK_01249	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HOFHCPNK_01250	7.41e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HOFHCPNK_01251	5.16e-221	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOFHCPNK_01252	1.17e-66	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOFHCPNK_01253	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOFHCPNK_01254	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HOFHCPNK_01255	2.73e-102	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HOFHCPNK_01256	1.62e-179	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOFHCPNK_01257	4.51e-199	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
HOFHCPNK_01258	5.42e-75	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HOFHCPNK_01259	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
HOFHCPNK_01260	0.0	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOFHCPNK_01261	3.38e-128	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
HOFHCPNK_01262	1.19e-45	-	-	-	-	-	-	-	-
HOFHCPNK_01263	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HOFHCPNK_01264	6.78e-270	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HOFHCPNK_01265	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOFHCPNK_01266	8.29e-292	-	-	-	G	-	-	-	Major Facilitator Superfamily
HOFHCPNK_01267	6.02e-246	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HOFHCPNK_01268	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HOFHCPNK_01269	9.78e-18	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HOFHCPNK_01270	2.58e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HOFHCPNK_01271	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOFHCPNK_01272	6.1e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HOFHCPNK_01273	5.35e-140	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HOFHCPNK_01274	5.25e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HOFHCPNK_01275	5.9e-188	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HOFHCPNK_01276	2.35e-126	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOFHCPNK_01277	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HOFHCPNK_01278	1.02e-198	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
HOFHCPNK_01279	3.25e-44	-	-	-	-	-	-	-	-
HOFHCPNK_01280	3.19e-145	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HOFHCPNK_01281	6.96e-33	-	-	-	-	-	-	-	-
HOFHCPNK_01282	2.52e-106	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HOFHCPNK_01283	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOFHCPNK_01284	9.41e-69	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HOFHCPNK_01285	1.53e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOFHCPNK_01286	3.68e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HOFHCPNK_01287	7.09e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOFHCPNK_01288	8.23e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HOFHCPNK_01289	1.39e-197	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HOFHCPNK_01290	3.89e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HOFHCPNK_01291	8.76e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOFHCPNK_01292	2.57e-168	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HOFHCPNK_01293	8.12e-113	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HOFHCPNK_01294	3.02e-170	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HOFHCPNK_01295	3.43e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HOFHCPNK_01296	8.61e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOFHCPNK_01297	6.62e-11	-	-	-	D	-	-	-	nuclear chromosome segregation
HOFHCPNK_01298	2.34e-11	-	-	-	D	-	-	-	nuclear chromosome segregation
HOFHCPNK_01299	6.8e-219	-	-	-	-	-	-	-	-
HOFHCPNK_01300	1.29e-80	-	-	-	-	-	-	-	-
HOFHCPNK_01301	3.27e-306	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HOFHCPNK_01302	1.49e-64	-	-	-	-	-	-	-	-
HOFHCPNK_01303	1.2e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HOFHCPNK_01304	8.5e-242	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HOFHCPNK_01305	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOFHCPNK_01306	3.38e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HOFHCPNK_01307	1.53e-102	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HOFHCPNK_01308	2.75e-64	-	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
HOFHCPNK_01309	1.01e-71	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HOFHCPNK_01310	3.25e-298	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HOFHCPNK_01311	2.19e-196	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HOFHCPNK_01312	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
HOFHCPNK_01313	0.0	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOFHCPNK_01314	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
HOFHCPNK_01315	6.18e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOFHCPNK_01316	1.51e-100	-	-	-	-	-	-	-	-
HOFHCPNK_01317	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HOFHCPNK_01318	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HOFHCPNK_01319	1.55e-133	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HOFHCPNK_01320	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
HOFHCPNK_01321	2.75e-167	-	-	-	S	-	-	-	membrane
HOFHCPNK_01322	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOFHCPNK_01323	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HOFHCPNK_01324	5.96e-09	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOFHCPNK_01325	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOFHCPNK_01326	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
HOFHCPNK_01327	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HOFHCPNK_01328	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HOFHCPNK_01329	1.26e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HOFHCPNK_01330	1.16e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HOFHCPNK_01331	1.08e-67	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HOFHCPNK_01332	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HOFHCPNK_01333	1.79e-267	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOFHCPNK_01334	2.44e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HOFHCPNK_01335	3.84e-299	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HOFHCPNK_01336	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOFHCPNK_01337	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HOFHCPNK_01338	1.01e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOFHCPNK_01339	1.27e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HOFHCPNK_01340	1.33e-118	cvpA	-	-	S	-	-	-	Colicin V production protein
HOFHCPNK_01341	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HOFHCPNK_01342	8.93e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HOFHCPNK_01343	2.57e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HOFHCPNK_01344	1.14e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HOFHCPNK_01345	4.91e-150	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOFHCPNK_01346	1.06e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOFHCPNK_01347	1.51e-203	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HOFHCPNK_01348	2.54e-33	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HOFHCPNK_01349	1.47e-67	-	-	-	-	-	-	-	-
HOFHCPNK_01350	1.54e-270	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HOFHCPNK_01351	2.52e-229	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HOFHCPNK_01352	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HOFHCPNK_01353	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
HOFHCPNK_01354	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HOFHCPNK_01355	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HOFHCPNK_01356	3.99e-74	-	-	-	-	-	-	-	-
HOFHCPNK_01357	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HOFHCPNK_01358	1.44e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HOFHCPNK_01359	4.87e-190	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HOFHCPNK_01360	1.62e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HOFHCPNK_01361	1.45e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HOFHCPNK_01362	2.17e-230	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HOFHCPNK_01363	2.37e-79	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
HOFHCPNK_01364	6.31e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOFHCPNK_01365	2.67e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HOFHCPNK_01366	6.19e-202	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HOFHCPNK_01367	6.07e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HOFHCPNK_01368	2.64e-49	-	-	-	-	-	-	-	-
HOFHCPNK_01369	8.75e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOFHCPNK_01370	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOFHCPNK_01371	2.35e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOFHCPNK_01372	1.29e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HOFHCPNK_01373	2.75e-308	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HOFHCPNK_01374	1.39e-156	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HOFHCPNK_01375	2.33e-262	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HOFHCPNK_01376	1.38e-312	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HOFHCPNK_01377	1.73e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOFHCPNK_01378	7.62e-126	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOFHCPNK_01379	1.85e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HOFHCPNK_01380	3.01e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HOFHCPNK_01381	2.58e-296	ymfH	-	-	S	-	-	-	Peptidase M16
HOFHCPNK_01382	3.51e-292	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HOFHCPNK_01383	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HOFHCPNK_01384	8.29e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HOFHCPNK_01385	1.88e-135	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HOFHCPNK_01386	4.6e-271	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HOFHCPNK_01387	1.88e-88	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HOFHCPNK_01388	6.1e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HOFHCPNK_01389	5.46e-300	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HOFHCPNK_01390	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HOFHCPNK_01391	2.38e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOFHCPNK_01392	2.24e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOFHCPNK_01393	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HOFHCPNK_01394	8.77e-144	-	-	-	S	-	-	-	CYTH
HOFHCPNK_01395	2.2e-139	yjbH	-	-	Q	-	-	-	Thioredoxin
HOFHCPNK_01396	4.94e-209	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HOFHCPNK_01397	2.82e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HOFHCPNK_01398	1e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HOFHCPNK_01399	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOFHCPNK_01400	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HOFHCPNK_01401	4.33e-36	-	-	-	-	-	-	-	-
HOFHCPNK_01402	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HOFHCPNK_01403	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HOFHCPNK_01404	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HOFHCPNK_01405	4.69e-202	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HOFHCPNK_01406	8.42e-102	-	-	-	-	-	-	-	-
HOFHCPNK_01407	4.08e-117	-	-	-	-	-	-	-	-
HOFHCPNK_01408	6.36e-147	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HOFHCPNK_01409	1.1e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HOFHCPNK_01410	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOFHCPNK_01411	2.41e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HOFHCPNK_01412	5.82e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HOFHCPNK_01413	4.31e-278	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HOFHCPNK_01414	5.22e-228	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HOFHCPNK_01416	6.93e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HOFHCPNK_01417	1.34e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOFHCPNK_01418	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HOFHCPNK_01419	3.2e-214	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOFHCPNK_01420	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HOFHCPNK_01421	1.47e-76	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HOFHCPNK_01422	1.15e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HOFHCPNK_01423	9.32e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HOFHCPNK_01424	1.17e-119	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HOFHCPNK_01425	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HOFHCPNK_01426	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HOFHCPNK_01427	0.0	-	-	-	S	-	-	-	membrane
HOFHCPNK_01428	3.09e-96	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOFHCPNK_01429	1.11e-261	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOFHCPNK_01430	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOFHCPNK_01431	9.43e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOFHCPNK_01432	1.01e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HOFHCPNK_01433	6.34e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOFHCPNK_01434	8.53e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HOFHCPNK_01435	2.72e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOFHCPNK_01436	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HOFHCPNK_01437	3.11e-169	csrR	-	-	K	-	-	-	response regulator
HOFHCPNK_01438	7.11e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HOFHCPNK_01439	1.45e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HOFHCPNK_01440	1.78e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HOFHCPNK_01441	2.26e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HOFHCPNK_01442	1.16e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOFHCPNK_01443	1.94e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HOFHCPNK_01444	1.25e-119	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HOFHCPNK_01445	2.75e-244	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HOFHCPNK_01446	3.54e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOFHCPNK_01447	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HOFHCPNK_01448	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOFHCPNK_01449	8.85e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
HOFHCPNK_01450	5.34e-218	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HOFHCPNK_01451	1.82e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HOFHCPNK_01452	6.56e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
HOFHCPNK_01453	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOFHCPNK_01454	4.54e-210	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HOFHCPNK_01455	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HOFHCPNK_01456	5.92e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOFHCPNK_01457	6.46e-137	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HOFHCPNK_01458	2.85e-206	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HOFHCPNK_01459	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOFHCPNK_01460	6.03e-292	dpaL	4.3.1.15	-	E	ko:K01751	-	ko00000,ko01000	Pyridoxal-phosphate dependent enzyme
HOFHCPNK_01461	4.61e-284	-	-	-	EGP	-	-	-	Major Facilitator
HOFHCPNK_01462	6.53e-90	-	-	-	K	-	-	-	Transcriptional regulator
HOFHCPNK_01463	1.92e-17	-	-	-	-	-	-	-	-
HOFHCPNK_01464	5.98e-100	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HOFHCPNK_01465	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HOFHCPNK_01466	7.5e-153	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HOFHCPNK_01467	1.23e-249	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOFHCPNK_01468	8.76e-121	-	-	-	S	-	-	-	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
HOFHCPNK_01469	2.92e-231	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HOFHCPNK_01470	0.0	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
HOFHCPNK_01471	8.28e-169	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HOFHCPNK_01472	6.18e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOFHCPNK_01473	4.28e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
HOFHCPNK_01474	3.11e-19	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HOFHCPNK_01475	1.34e-53	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HOFHCPNK_01476	3.87e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HOFHCPNK_01477	3.63e-289	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HOFHCPNK_01478	3.26e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_01479	1.01e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HOFHCPNK_01480	4.48e-90	-	-	-	-	-	-	-	-
HOFHCPNK_01481	2.42e-72	-	-	-	S	-	-	-	YtxH-like protein
HOFHCPNK_01482	5.88e-201	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HOFHCPNK_01483	1.3e-238	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOFHCPNK_01484	0.0	yhaN	-	-	L	-	-	-	AAA domain
HOFHCPNK_01485	5.64e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HOFHCPNK_01486	3.16e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HOFHCPNK_01487	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HOFHCPNK_01488	1.07e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HOFHCPNK_01490	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HOFHCPNK_01491	1.43e-87	-	-	-	-	-	-	-	-
HOFHCPNK_01492	1.11e-123	-	-	-	L	-	-	-	NUDIX domain
HOFHCPNK_01493	2.08e-196	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
HOFHCPNK_01494	2.11e-253	flp	-	-	V	-	-	-	Beta-lactamase
HOFHCPNK_01496	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HOFHCPNK_01497	3.24e-51	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction
HOFHCPNK_01498	3.88e-50	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HOFHCPNK_01499	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HOFHCPNK_01500	4.26e-32	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HOFHCPNK_01501	3.22e-137	-	-	-	F	-	-	-	helicase superfamily c-terminal domain
HOFHCPNK_01504	6.8e-32	-	-	-	-	-	-	-	-
HOFHCPNK_01505	3.92e-38	-	-	-	-	-	-	-	-
HOFHCPNK_01506	2.69e-256	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HOFHCPNK_01507	1.44e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HOFHCPNK_01508	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
HOFHCPNK_01509	2.81e-88	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFHCPNK_01510	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HOFHCPNK_01511	1.06e-62	-	-	-	S	-	-	-	VRR_NUC
HOFHCPNK_01512	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HOFHCPNK_01513	3.56e-113	-	-	-	-	-	-	-	-
HOFHCPNK_01514	2.4e-130	-	-	-	-	-	-	-	-
HOFHCPNK_01515	8.18e-309	-	-	-	KL	-	-	-	DNA methylase
HOFHCPNK_01516	3.2e-150	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFHCPNK_01517	2.05e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
HOFHCPNK_01518	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HOFHCPNK_01519	4.58e-308	-	-	-	S	-	-	-	Phage portal protein
HOFHCPNK_01520	4.66e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HOFHCPNK_01521	1.58e-282	-	-	-	S	-	-	-	Phage capsid family
HOFHCPNK_01522	3.08e-57	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HOFHCPNK_01523	1.29e-88	-	-	-	S	-	-	-	Phage head-tail joining protein
HOFHCPNK_01524	5.95e-92	-	-	-	S	-	-	-	Bacteriophage holin family
HOFHCPNK_01525	3.19e-186	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HOFHCPNK_01526	3.04e-48	-	-	-	-	-	-	-	-
HOFHCPNK_01527	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HOFHCPNK_01528	0.0	-	-	-	L	-	-	-	Recombinase
HOFHCPNK_01529	8.23e-23	-	2.1.1.303	-	K	ko:K04096,ko:K20421	ko01059,ko01130,map01059,map01130	ko00000,ko00001,ko00002,ko01000	DNA-binding transcription factor activity
HOFHCPNK_01530	1.21e-35	-	-	-	M	-	-	-	domain protein
HOFHCPNK_01532	1.73e-89	-	-	-	-	-	-	-	-
HOFHCPNK_01533	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HOFHCPNK_01534	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HOFHCPNK_01535	2.22e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HOFHCPNK_01536	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOFHCPNK_01537	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOFHCPNK_01538	7.94e-202	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HOFHCPNK_01539	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
HOFHCPNK_01540	3.93e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOFHCPNK_01541	7.9e-212	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HOFHCPNK_01542	9.65e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HOFHCPNK_01543	3.14e-311	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOFHCPNK_01544	4.36e-105	-	-	-	L	-	-	-	MgsA AAA+ ATPase C terminal
HOFHCPNK_01545	1.97e-159	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HOFHCPNK_01546	9.08e-176	-	-	-	S	-	-	-	Peptidase_C39 like family
HOFHCPNK_01547	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HOFHCPNK_01548	7.5e-153	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HOFHCPNK_01550	4.02e-208	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HOFHCPNK_01551	4.12e-316	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HOFHCPNK_01552	0.0	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HOFHCPNK_01553	4.84e-60	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HOFHCPNK_01554	1.38e-186	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HOFHCPNK_01555	2.81e-165	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HOFHCPNK_01556	1.77e-67	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HOFHCPNK_01557	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HOFHCPNK_01558	6.23e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HOFHCPNK_01559	5.76e-70	-	-	-	-	-	-	-	-
HOFHCPNK_01560	6e-35	-	-	-	-	-	-	-	-
HOFHCPNK_01561	6.19e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HOFHCPNK_01562	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HOFHCPNK_01563	4.63e-173	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_01564	0.0	-	-	-	E	-	-	-	Amino Acid
HOFHCPNK_01565	3.7e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOFHCPNK_01566	4.24e-298	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HOFHCPNK_01567	3.06e-194	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HOFHCPNK_01569	5.01e-128	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HOFHCPNK_01570	3.52e-58	-	-	-	-	-	-	-	-
HOFHCPNK_01571	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HOFHCPNK_01572	3.86e-143	-	-	-	-	-	-	-	-
HOFHCPNK_01573	3.86e-107	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HOFHCPNK_01574	3.52e-232	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOFHCPNK_01575	6.76e-106	-	-	-	-	-	-	-	-
HOFHCPNK_01576	3.75e-79	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HOFHCPNK_01577	5.2e-54	-	-	-	-	-	-	-	-
HOFHCPNK_01578	1.1e-103	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HOFHCPNK_01579	9.33e-179	-	-	-	S	-	-	-	Putative threonine/serine exporter
HOFHCPNK_01580	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HOFHCPNK_01581	9.18e-83	-	-	-	-	-	-	-	-
HOFHCPNK_01582	5.64e-54	-	-	-	-	-	-	-	-
HOFHCPNK_01583	1.04e-271	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HOFHCPNK_01584	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HOFHCPNK_01586	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HOFHCPNK_01587	8.87e-174	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HOFHCPNK_01588	2.22e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HOFHCPNK_01589	3.83e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HOFHCPNK_01590	4.8e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HOFHCPNK_01591	2.02e-179	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HOFHCPNK_01592	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HOFHCPNK_01593	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HOFHCPNK_01594	5.13e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HOFHCPNK_01595	2.29e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HOFHCPNK_01596	4.79e-56	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HOFHCPNK_01597	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HOFHCPNK_01598	1.07e-282	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HOFHCPNK_01599	9.23e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_01600	1.29e-184	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HOFHCPNK_01601	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOFHCPNK_01602	1.85e-264	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HOFHCPNK_01603	2.39e-156	vanR	-	-	K	-	-	-	response regulator
HOFHCPNK_01604	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HOFHCPNK_01605	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_01606	3.82e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HOFHCPNK_01607	9.37e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HOFHCPNK_01608	2.58e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HOFHCPNK_01609	9.01e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HOFHCPNK_01610	7.1e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HOFHCPNK_01611	1.28e-197	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HOFHCPNK_01612	8.33e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HOFHCPNK_01613	1.5e-123	cvpA	-	-	S	-	-	-	Colicin V production protein
HOFHCPNK_01614	1.33e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HOFHCPNK_01615	1.06e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HOFHCPNK_01616	3.26e-254	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HOFHCPNK_01617	4.45e-128	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HOFHCPNK_01618	9.4e-128	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HOFHCPNK_01619	6.92e-141	-	-	-	K	-	-	-	WHG domain
HOFHCPNK_01620	6.73e-51	-	-	-	-	-	-	-	-
HOFHCPNK_01621	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOFHCPNK_01622	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOFHCPNK_01623	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOFHCPNK_01624	5.09e-203	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HOFHCPNK_01625	3.67e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_01626	2.91e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HOFHCPNK_01627	2.72e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOFHCPNK_01628	9.98e-146	-	-	-	G	-	-	-	phosphoglycerate mutase
HOFHCPNK_01629	8.8e-149	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HOFHCPNK_01630	1.53e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HOFHCPNK_01631	1.58e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HOFHCPNK_01632	3.01e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HOFHCPNK_01633	4.81e-69	-	-	-	-	-	-	-	-
HOFHCPNK_01634	4.68e-168	-	-	-	-	-	-	-	-
HOFHCPNK_01635	6.19e-208	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HOFHCPNK_01636	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HOFHCPNK_01637	2.92e-183	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HOFHCPNK_01638	9.8e-197	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HOFHCPNK_01639	4.62e-223	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HOFHCPNK_01640	5.74e-71	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
HOFHCPNK_01641	2.49e-201	-	-	-	-	-	-	-	-
HOFHCPNK_01642	1.31e-287	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HOFHCPNK_01643	2.4e-160	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HOFHCPNK_01644	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HOFHCPNK_01645	1.59e-120	ymdB	-	-	S	-	-	-	Macro domain protein
HOFHCPNK_01646	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOFHCPNK_01647	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HOFHCPNK_01648	1.19e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOFHCPNK_01649	2.82e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HOFHCPNK_01650	1.38e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HOFHCPNK_01651	8.43e-170	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HOFHCPNK_01652	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HOFHCPNK_01653	1.52e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HOFHCPNK_01654	6.86e-246	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HOFHCPNK_01655	3.99e-299	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HOFHCPNK_01656	6.26e-306	-	-	-	E	-	-	-	amino acid
HOFHCPNK_01657	1.02e-177	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HOFHCPNK_01658	1.01e-311	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HOFHCPNK_01659	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HOFHCPNK_01660	4.26e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HOFHCPNK_01661	2.46e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HOFHCPNK_01662	1.23e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HOFHCPNK_01663	1.51e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HOFHCPNK_01665	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOFHCPNK_01666	6.34e-156	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HOFHCPNK_01667	3.41e-168	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_01668	2.12e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HOFHCPNK_01669	1.36e-209	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HOFHCPNK_01670	1.8e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HOFHCPNK_01671	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOFHCPNK_01672	5.56e-183	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HOFHCPNK_01673	3.27e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HOFHCPNK_01674	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HOFHCPNK_01675	3.15e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HOFHCPNK_01676	1.19e-113	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HOFHCPNK_01677	5.03e-122	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
HOFHCPNK_01678	1.86e-165	-	-	-	L	-	-	-	Helix-turn-helix domain
HOFHCPNK_01679	7.5e-29	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOFHCPNK_01680	1.61e-49	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOFHCPNK_01681	1.51e-194	-	-	-	S	-	-	-	hydrolase
HOFHCPNK_01683	1.86e-215	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HOFHCPNK_01684	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOFHCPNK_01685	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HOFHCPNK_01686	1.29e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOFHCPNK_01687	4.64e-265	camS	-	-	S	-	-	-	sex pheromone
HOFHCPNK_01688	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOFHCPNK_01689	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HOFHCPNK_01690	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HOFHCPNK_01691	4.37e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HOFHCPNK_01693	8.17e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HOFHCPNK_01694	7.2e-174	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HOFHCPNK_01695	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HOFHCPNK_01696	1.79e-292	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOFHCPNK_01697	1.29e-189	-	-	-	-	-	-	-	-
HOFHCPNK_01698	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HOFHCPNK_01699	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HOFHCPNK_01700	6.16e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HOFHCPNK_01701	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOFHCPNK_01702	1.68e-67	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HOFHCPNK_01703	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HOFHCPNK_01704	7.18e-259	-	-	-	M	-	-	-	Glycosyl transferases group 1
HOFHCPNK_01705	1.75e-182	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HOFHCPNK_01706	2.31e-87	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HOFHCPNK_01707	6.31e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HOFHCPNK_01708	2.15e-246	-	-	-	-	-	-	-	-
HOFHCPNK_01709	1.44e-69	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
HOFHCPNK_01712	1.53e-214	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HOFHCPNK_01713	1.43e-187	-	-	-	K	-	-	-	SIS domain
HOFHCPNK_01715	3.9e-243	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HOFHCPNK_01716	7.78e-80	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HOFHCPNK_01718	2.22e-159	-	-	-	M	-	-	-	LysM domain protein
HOFHCPNK_01719	4.59e-175	-	-	-	M	-	-	-	LysM domain protein
HOFHCPNK_01720	1.83e-175	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HOFHCPNK_01721	1.45e-232	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HOFHCPNK_01722	1.73e-87	-	-	-	S	-	-	-	Pfam:Phage_holin_6_1
HOFHCPNK_01723	5.31e-58	-	-	-	-	-	-	-	-
HOFHCPNK_01724	1e-84	-	-	-	-	-	-	-	-
HOFHCPNK_01726	3.59e-113	-	-	-	-	-	-	-	-
HOFHCPNK_01727	0.0	-	-	-	-	-	-	-	-
HOFHCPNK_01728	3.5e-126	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2313)
HOFHCPNK_01729	8.59e-271	-	-	-	S	-	-	-	Baseplate J-like protein
HOFHCPNK_01730	9.94e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HOFHCPNK_01731	6.7e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HOFHCPNK_01732	2.21e-253	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
HOFHCPNK_01733	8.91e-154	xkdP	-	-	S	-	-	-	protein containing LysM domain
HOFHCPNK_01734	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
HOFHCPNK_01735	1.57e-88	xkdN	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HOFHCPNK_01736	3.04e-110	-	-	-	S	-	-	-	Phage tail tube protein
HOFHCPNK_01737	1.67e-307	-	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HOFHCPNK_01738	8.81e-39	-	-	-	-	-	-	-	-
HOFHCPNK_01739	4.75e-91	-	-	-	-	-	-	-	-
HOFHCPNK_01740	5.61e-98	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HOFHCPNK_01741	1.55e-79	-	-	-	-	-	-	-	-
HOFHCPNK_01742	7.13e-87	-	-	-	-	-	-	-	-
HOFHCPNK_01743	2.94e-242	-	-	-	-	-	-	-	-
HOFHCPNK_01744	1.48e-117	-	-	-	S	-	-	-	viral scaffold
HOFHCPNK_01745	6.92e-282	-	-	-	S	-	-	-	Phage Mu protein F like protein
HOFHCPNK_01746	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HOFHCPNK_01747	1.01e-314	-	-	-	S	-	-	-	DNA packaging
HOFHCPNK_01748	3.95e-115	-	-	-	S	-	-	-	Terminase small subunit
HOFHCPNK_01749	2.06e-152	-	-	-	-	-	-	-	-
HOFHCPNK_01751	4.56e-154	-	-	-	C	-	-	-	Domain of unknown function (DUF4145)
HOFHCPNK_01752	4.13e-65	-	-	-	K	-	-	-	chromosome segregation
HOFHCPNK_01754	1.83e-123	-	-	-	-	-	-	-	-
HOFHCPNK_01755	3.18e-16	-	-	-	-	-	-	-	-
HOFHCPNK_01756	2.62e-40	-	-	-	-	-	-	-	-
HOFHCPNK_01757	1.97e-48	-	-	-	-	-	-	-	-
HOFHCPNK_01758	2.42e-30	-	-	-	-	-	-	-	-
HOFHCPNK_01759	4.17e-102	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HOFHCPNK_01764	5.21e-41	-	-	-	-	-	-	-	-
HOFHCPNK_01766	8.57e-163	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
HOFHCPNK_01768	1.79e-26	-	-	-	S	-	-	-	sequence-specific DNA binding
HOFHCPNK_01769	3.23e-51	-	-	-	L	-	-	-	Helix-turn-helix domain
HOFHCPNK_01770	1.78e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
HOFHCPNK_01772	1.15e-73	-	-	-	-	-	-	-	-
HOFHCPNK_01773	1.73e-22	-	-	-	-	-	-	-	-
HOFHCPNK_01778	1.39e-70	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HOFHCPNK_01779	3.93e-07	-	-	-	K	-	-	-	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOFHCPNK_01780	1.98e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
HOFHCPNK_01781	5.98e-105	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HOFHCPNK_01782	4.6e-128	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
HOFHCPNK_01784	7.41e-156	-	-	-	S	-	-	-	Phage integrase family
HOFHCPNK_01785	7.85e-80	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HOFHCPNK_01786	1.7e-122	-	-	-	K	-	-	-	acetyltransferase
HOFHCPNK_01787	7.35e-198	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HOFHCPNK_01789	1.53e-210	yvgN	-	-	C	-	-	-	Aldo keto reductase
HOFHCPNK_01790	1.45e-313	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HOFHCPNK_01791	1.3e-301	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOFHCPNK_01792	3.29e-132	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HOFHCPNK_01793	1.03e-138	-	-	-	S	-	-	-	SNARE associated Golgi protein
HOFHCPNK_01794	6.43e-196	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOFHCPNK_01795	1.73e-184	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HOFHCPNK_01796	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HOFHCPNK_01797	1.05e-229	-	-	-	-	-	-	-	-
HOFHCPNK_01798	3.24e-159	-	-	-	S	-	-	-	SNARE associated Golgi protein
HOFHCPNK_01799	3.15e-175	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HOFHCPNK_01800	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HOFHCPNK_01801	3.6e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOFHCPNK_01802	8.18e-216	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HOFHCPNK_01803	1.59e-214	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HOFHCPNK_01804	1.27e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HOFHCPNK_01805	2.29e-125	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HOFHCPNK_01806	1.84e-100	yybA	-	-	K	-	-	-	Transcriptional regulator
HOFHCPNK_01807	7.83e-74	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HOFHCPNK_01808	1.38e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOFHCPNK_01809	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
HOFHCPNK_01810	3.39e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOFHCPNK_01811	4.34e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HOFHCPNK_01812	9.81e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOFHCPNK_01813	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOFHCPNK_01814	1.46e-202	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HOFHCPNK_01815	3.26e-17	dkgB	-	-	S	-	-	-	reductase
HOFHCPNK_01816	1.43e-97	dkgB	-	-	S	-	-	-	reductase
HOFHCPNK_01817	6.36e-257	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HOFHCPNK_01818	1.2e-236	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HOFHCPNK_01819	5.38e-180	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HOFHCPNK_01820	7.18e-145	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HOFHCPNK_01821	1.16e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HOFHCPNK_01822	3.53e-314	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HOFHCPNK_01823	1.83e-124	-	-	-	S	-	-	-	PAS domain
HOFHCPNK_01824	1.7e-188	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HOFHCPNK_01825	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HOFHCPNK_01826	3.06e-06	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HOFHCPNK_01827	1.29e-69	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HOFHCPNK_01828	5.83e-205	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HOFHCPNK_01829	4.63e-169	-	-	-	S	-	-	-	PAS domain
HOFHCPNK_01830	3.52e-303	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOFHCPNK_01831	2.47e-275	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HOFHCPNK_01832	4.41e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOFHCPNK_01833	1.2e-30	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HOFHCPNK_01834	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HOFHCPNK_01835	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
HOFHCPNK_01836	0.0	-	-	-	S	-	-	-	TerB-C domain
HOFHCPNK_01837	6.11e-129	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HOFHCPNK_01838	1.41e-93	-	-	-	-	-	-	-	-
HOFHCPNK_01839	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HOFHCPNK_01840	3.99e-256	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HOFHCPNK_01841	1.75e-296	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HOFHCPNK_01842	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HOFHCPNK_01843	3.15e-232	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HOFHCPNK_01844	3.53e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HOFHCPNK_01845	2.31e-281	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
HOFHCPNK_01857	1.09e-79	-	-	-	-	-	-	-	-