Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HBDLGIIM_00001	2.34e-148	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HBDLGIIM_00002	5.2e-118	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBDLGIIM_00003	6.22e-204	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HBDLGIIM_00004	9.2e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
HBDLGIIM_00005	1.73e-172	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HBDLGIIM_00006	4.8e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HBDLGIIM_00007	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HBDLGIIM_00008	1.81e-200	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HBDLGIIM_00009	5.4e-127	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HBDLGIIM_00010	3.93e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HBDLGIIM_00011	2.3e-227	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBDLGIIM_00012	1.82e-275	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HBDLGIIM_00013	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HBDLGIIM_00014	1.27e-17	degR	-	-	-	-	-	-	-
HBDLGIIM_00015	6.52e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HBDLGIIM_00016	6.59e-40	ypeQ	-	-	S	-	-	-	Zinc-finger
HBDLGIIM_00017	2.06e-159	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HBDLGIIM_00018	3.96e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HBDLGIIM_00019	1.22e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HBDLGIIM_00021	3.33e-210	ypcP	-	-	L	-	-	-	5'3' exonuclease
HBDLGIIM_00022	4.92e-10	-	-	-	-	-	-	-	-
HBDLGIIM_00023	7.03e-53	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HBDLGIIM_00024	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HBDLGIIM_00025	1.26e-117	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HBDLGIIM_00026	5.13e-268	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HBDLGIIM_00027	2.94e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HBDLGIIM_00028	3.81e-67	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
HBDLGIIM_00029	8.58e-09	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HBDLGIIM_00030	4.76e-127	yrdC	-	-	Q	-	-	-	Isochorismatase family
HBDLGIIM_00031	1.97e-295	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
HBDLGIIM_00032	1.92e-127	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HBDLGIIM_00033	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HBDLGIIM_00034	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HBDLGIIM_00036	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
HBDLGIIM_00037	4.48e-274	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HBDLGIIM_00038	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HBDLGIIM_00039	5.42e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HBDLGIIM_00040	9.36e-48	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HBDLGIIM_00042	1.64e-301	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HBDLGIIM_00043	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HBDLGIIM_00044	1.21e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HBDLGIIM_00045	1.85e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HBDLGIIM_00046	1.59e-75	yppG	-	-	S	-	-	-	YppG-like protein
HBDLGIIM_00050	0.000542	-	-	-	-	ko:K06430	-	ko00000	-
HBDLGIIM_00051	7.83e-237	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HBDLGIIM_00052	3.6e-145	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HBDLGIIM_00053	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HBDLGIIM_00054	1.74e-117	ypoC	-	-	-	-	-	-	-
HBDLGIIM_00055	4.87e-156	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBDLGIIM_00056	3.42e-167	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HBDLGIIM_00057	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HBDLGIIM_00058	1.46e-283	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HBDLGIIM_00059	9.65e-105	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_00060	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HBDLGIIM_00061	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HBDLGIIM_00062	2.41e-84	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HBDLGIIM_00063	5.71e-202	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HBDLGIIM_00064	1.14e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HBDLGIIM_00065	1.82e-229	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HBDLGIIM_00066	2.41e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HBDLGIIM_00067	1.54e-270	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HBDLGIIM_00068	2.59e-169	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HBDLGIIM_00069	6.19e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HBDLGIIM_00070	4.65e-187	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HBDLGIIM_00071	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HBDLGIIM_00072	4.31e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBDLGIIM_00073	9.57e-288	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HBDLGIIM_00074	1.68e-181	ypjB	-	-	S	-	-	-	sporulation protein
HBDLGIIM_00075	1.2e-132	ypjA	-	-	S	-	-	-	membrane
HBDLGIIM_00076	8.11e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HBDLGIIM_00077	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HBDLGIIM_00078	2.86e-127	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HBDLGIIM_00079	1.66e-101	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HBDLGIIM_00080	7.45e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HBDLGIIM_00081	7.49e-299	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HBDLGIIM_00082	2.14e-296	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HBDLGIIM_00083	3.57e-260	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HBDLGIIM_00084	1.44e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HBDLGIIM_00085	1.33e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HBDLGIIM_00086	1.73e-290	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HBDLGIIM_00087	1.5e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HBDLGIIM_00088	1e-168	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HBDLGIIM_00089	9.63e-211	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBDLGIIM_00090	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBDLGIIM_00091	1.7e-78	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HBDLGIIM_00092	1.11e-260	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HBDLGIIM_00093	9.75e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HBDLGIIM_00094	2.73e-179	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HBDLGIIM_00095	8.53e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HBDLGIIM_00096	2.29e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HBDLGIIM_00097	7.76e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HBDLGIIM_00098	1.33e-175	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HBDLGIIM_00099	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HBDLGIIM_00100	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HBDLGIIM_00101	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HBDLGIIM_00102	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HBDLGIIM_00103	3.97e-172	yphF	-	-	-	-	-	-	-
HBDLGIIM_00104	3.25e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HBDLGIIM_00105	4.93e-244	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HBDLGIIM_00106	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HBDLGIIM_00107	7.23e-135	yphA	-	-	-	-	-	-	-
HBDLGIIM_00108	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
HBDLGIIM_00109	5.67e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HBDLGIIM_00110	8.14e-264	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HBDLGIIM_00111	1.94e-144	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HBDLGIIM_00112	7.86e-18	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HBDLGIIM_00113	5e-79	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HBDLGIIM_00114	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HBDLGIIM_00115	3.77e-213	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HBDLGIIM_00116	6.4e-156	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HBDLGIIM_00117	5.3e-239	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HBDLGIIM_00118	1.81e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HBDLGIIM_00119	3.35e-137	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HBDLGIIM_00120	3.84e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HBDLGIIM_00121	1.92e-111	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HBDLGIIM_00122	5.85e-124	ypbE	-	-	M	-	-	-	Lysin motif
HBDLGIIM_00123	1.09e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HBDLGIIM_00124	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBDLGIIM_00125	3.37e-250	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HBDLGIIM_00126	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HBDLGIIM_00127	2.16e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HBDLGIIM_00128	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBDLGIIM_00129	4.62e-253	rsiX	-	-	-	-	-	-	-
HBDLGIIM_00130	3.09e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBDLGIIM_00131	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_00132	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_00133	6.24e-252	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HBDLGIIM_00134	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HBDLGIIM_00135	4.31e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HBDLGIIM_00136	7.38e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HBDLGIIM_00137	2.58e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HBDLGIIM_00138	3.75e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HBDLGIIM_00139	7.68e-274	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HBDLGIIM_00140	1.84e-110	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HBDLGIIM_00141	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBDLGIIM_00142	2.09e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBDLGIIM_00144	6.67e-120	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HBDLGIIM_00145	2.74e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBDLGIIM_00146	6.92e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HBDLGIIM_00147	1.04e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBDLGIIM_00148	3.97e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HBDLGIIM_00149	3.76e-268	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBDLGIIM_00150	2.01e-70	ypuD	-	-	-	-	-	-	-
HBDLGIIM_00151	8.95e-129	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HBDLGIIM_00152	2.75e-105	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
HBDLGIIM_00153	1.96e-102	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBDLGIIM_00154	2.29e-199	ypuA	-	-	S	-	-	-	Secreted protein
HBDLGIIM_00155	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HBDLGIIM_00156	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HBDLGIIM_00157	5.32e-142	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HBDLGIIM_00158	1.51e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HBDLGIIM_00159	1.65e-243	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HBDLGIIM_00160	2.85e-103	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HBDLGIIM_00161	1.43e-78	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HBDLGIIM_00162	6.68e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HBDLGIIM_00163	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBDLGIIM_00164	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HBDLGIIM_00165	4.86e-77	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HBDLGIIM_00166	1.43e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HBDLGIIM_00167	1.83e-191	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HBDLGIIM_00168	4.97e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HBDLGIIM_00169	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HBDLGIIM_00170	9.51e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HBDLGIIM_00171	4.56e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HBDLGIIM_00172	3.53e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HBDLGIIM_00173	4.38e-47	yqkK	-	-	-	-	-	-	-
HBDLGIIM_00174	1.96e-30	-	-	-	-	-	-	-	-
HBDLGIIM_00175	4.12e-310	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HBDLGIIM_00176	5.89e-312	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HBDLGIIM_00177	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HBDLGIIM_00178	1.3e-240	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HBDLGIIM_00179	1.63e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_00180	4.16e-280	yqxK	-	-	L	-	-	-	DNA helicase
HBDLGIIM_00181	1.04e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HBDLGIIM_00182	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HBDLGIIM_00183	2.18e-216	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HBDLGIIM_00184	1.45e-11	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HBDLGIIM_00185	8.24e-226	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HBDLGIIM_00186	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HBDLGIIM_00187	1.09e-79	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HBDLGIIM_00188	1.76e-224	yqkA	-	-	K	-	-	-	GrpB protein
HBDLGIIM_00189	6.98e-80	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HBDLGIIM_00190	6.63e-114	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HBDLGIIM_00191	2.7e-298	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBDLGIIM_00192	9.19e-76	-	-	-	S	-	-	-	YolD-like protein
HBDLGIIM_00194	1.61e-235	yueF	-	-	S	-	-	-	transporter activity
HBDLGIIM_00196	4.44e-95	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBDLGIIM_00197	6.33e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HBDLGIIM_00198	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HBDLGIIM_00199	5.87e-181	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBDLGIIM_00200	1.61e-222	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HBDLGIIM_00201	4.1e-187	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBDLGIIM_00202	1.38e-174	-	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HBDLGIIM_00203	2.25e-305	-	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HBDLGIIM_00204	8.08e-281	-	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HBDLGIIM_00205	0.0	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HBDLGIIM_00206	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_00207	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_00208	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_00209	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_00210	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_00211	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_00212	1.32e-166	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HBDLGIIM_00213	6.45e-313	-	6.1.3.1, 6.2.1.3, 6.2.1.34	-	IQ	ko:K00666,ko:K01897,ko:K12508,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HBDLGIIM_00216	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HBDLGIIM_00217	4.32e-122	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HBDLGIIM_00218	1.36e-212	-	-	-	K	-	-	-	LysR substrate binding domain
HBDLGIIM_00219	1.11e-66	-	-	-	S	-	-	-	GlpM protein
HBDLGIIM_00220	1.27e-247	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HBDLGIIM_00221	2.23e-189	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HBDLGIIM_00222	3.77e-218	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HBDLGIIM_00223	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBDLGIIM_00224	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HBDLGIIM_00225	3.31e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBDLGIIM_00226	1.3e-34	yqzJ	-	-	-	-	-	-	-
HBDLGIIM_00227	2.91e-191	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBDLGIIM_00228	1.06e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HBDLGIIM_00229	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HBDLGIIM_00230	1.33e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HBDLGIIM_00232	3.7e-123	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_00233	1.6e-219	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HBDLGIIM_00234	3.51e-164	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HBDLGIIM_00235	1.04e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HBDLGIIM_00236	3.37e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HBDLGIIM_00237	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HBDLGIIM_00238	4.97e-218	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HBDLGIIM_00239	6.94e-282	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HBDLGIIM_00240	1.7e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HBDLGIIM_00241	9.42e-214	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HBDLGIIM_00242	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HBDLGIIM_00243	1.2e-263	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HBDLGIIM_00244	2.61e-260	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HBDLGIIM_00245	2.37e-195	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HBDLGIIM_00246	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HBDLGIIM_00247	6.25e-47	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HBDLGIIM_00248	6.63e-204	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HBDLGIIM_00249	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HBDLGIIM_00250	7.23e-263	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HBDLGIIM_00251	1.07e-261	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HBDLGIIM_00252	4.65e-195	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HBDLGIIM_00253	1.32e-270	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HBDLGIIM_00254	1.56e-174	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HBDLGIIM_00255	6.87e-137	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HBDLGIIM_00257	1.96e-131	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HBDLGIIM_00258	1.15e-145	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
HBDLGIIM_00260	4.59e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HBDLGIIM_00263	2.04e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBDLGIIM_00264	6.11e-187	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HBDLGIIM_00265	1.79e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HBDLGIIM_00266	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HBDLGIIM_00267	4.38e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HBDLGIIM_00268	2.93e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HBDLGIIM_00269	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HBDLGIIM_00270	1.11e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HBDLGIIM_00271	2.67e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBDLGIIM_00272	1.6e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBDLGIIM_00273	3.05e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HBDLGIIM_00274	2.2e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HBDLGIIM_00275	1.36e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_00276	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HBDLGIIM_00277	4.67e-86	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HBDLGIIM_00278	2.74e-94	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HBDLGIIM_00279	9.98e-150	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HBDLGIIM_00280	4.98e-129	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HBDLGIIM_00281	5.23e-261	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HBDLGIIM_00282	3.72e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HBDLGIIM_00283	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HBDLGIIM_00284	1.7e-112	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HBDLGIIM_00285	3.12e-221	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HBDLGIIM_00286	9.89e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HBDLGIIM_00287	6.82e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HBDLGIIM_00288	6.04e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HBDLGIIM_00289	5.66e-118	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HBDLGIIM_00290	7.33e-221	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HBDLGIIM_00291	7.65e-83	yqhP	-	-	-	-	-	-	-
HBDLGIIM_00292	2.85e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HBDLGIIM_00293	5.64e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HBDLGIIM_00294	1.58e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HBDLGIIM_00295	3.18e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HBDLGIIM_00296	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HBDLGIIM_00297	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HBDLGIIM_00298	1.84e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HBDLGIIM_00299	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HBDLGIIM_00300	5.29e-196	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HBDLGIIM_00301	2.31e-32	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HBDLGIIM_00302	2.75e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HBDLGIIM_00303	1.82e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HBDLGIIM_00304	3.27e-103	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HBDLGIIM_00305	1.98e-157	yqxM	-	-	-	ko:K19433	-	ko00000	-
HBDLGIIM_00306	4.84e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HBDLGIIM_00307	2e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
HBDLGIIM_00308	4.03e-82	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HBDLGIIM_00309	2.22e-85	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HBDLGIIM_00310	2.21e-26	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HBDLGIIM_00311	2.66e-92	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
HBDLGIIM_00312	5.22e-65	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HBDLGIIM_00313	3.13e-231	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HBDLGIIM_00314	1.1e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HBDLGIIM_00315	6.43e-239	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HBDLGIIM_00316	2.65e-304	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HBDLGIIM_00317	2.05e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HBDLGIIM_00319	1.15e-86	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HBDLGIIM_00320	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HBDLGIIM_00321	5.73e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HBDLGIIM_00322	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HBDLGIIM_00323	2.99e-65	dglA	-	-	S	-	-	-	Thiamine-binding protein
HBDLGIIM_00324	1.55e-255	yqgU	-	-	-	-	-	-	-
HBDLGIIM_00325	5.91e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HBDLGIIM_00326	2.91e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HBDLGIIM_00327	9.1e-39	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
HBDLGIIM_00328	1.3e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HBDLGIIM_00329	1.88e-11	yqgO	-	-	-	-	-	-	-
HBDLGIIM_00330	2.57e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBDLGIIM_00331	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HBDLGIIM_00332	3.42e-68	yqzD	-	-	-	-	-	-	-
HBDLGIIM_00333	2.4e-97	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBDLGIIM_00334	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HBDLGIIM_00335	8.33e-186	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HBDLGIIM_00336	5.88e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HBDLGIIM_00337	1.75e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HBDLGIIM_00338	2.72e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HBDLGIIM_00339	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HBDLGIIM_00340	2.37e-289	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HBDLGIIM_00341	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HBDLGIIM_00342	2.76e-99	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HBDLGIIM_00343	1.08e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HBDLGIIM_00344	3.05e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HBDLGIIM_00345	5.64e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HBDLGIIM_00346	3.34e-80	yqfX	-	-	S	-	-	-	membrane
HBDLGIIM_00347	7.06e-143	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HBDLGIIM_00348	2.25e-100	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HBDLGIIM_00349	5.44e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBDLGIIM_00350	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HBDLGIIM_00351	1.72e-213	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HBDLGIIM_00352	6.06e-308	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HBDLGIIM_00353	4.16e-89	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HBDLGIIM_00354	2.04e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HBDLGIIM_00355	1.53e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBDLGIIM_00356	2.01e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HBDLGIIM_00357	9.68e-83	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HBDLGIIM_00358	3.97e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HBDLGIIM_00359	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HBDLGIIM_00360	1.36e-112	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HBDLGIIM_00361	7.44e-190	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HBDLGIIM_00362	5.89e-145	ccpN	-	-	K	-	-	-	CBS domain
HBDLGIIM_00363	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HBDLGIIM_00364	5.19e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HBDLGIIM_00365	5.05e-185	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HBDLGIIM_00366	6e-24	-	-	-	S	-	-	-	YqzL-like protein
HBDLGIIM_00367	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBDLGIIM_00368	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HBDLGIIM_00369	5.28e-83	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HBDLGIIM_00370	1.44e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HBDLGIIM_00371	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HBDLGIIM_00372	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HBDLGIIM_00373	1.3e-282	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HBDLGIIM_00374	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HBDLGIIM_00375	2.97e-84	yqfB	-	-	-	-	-	-	-
HBDLGIIM_00376	4.78e-177	yqfA	-	-	S	-	-	-	UPF0365 protein
HBDLGIIM_00377	9.41e-296	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HBDLGIIM_00378	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HBDLGIIM_00379	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HBDLGIIM_00380	2.38e-202	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HBDLGIIM_00381	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HBDLGIIM_00382	1.75e-181	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HBDLGIIM_00383	1.55e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HBDLGIIM_00384	4.93e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HBDLGIIM_00385	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HBDLGIIM_00386	5.18e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HBDLGIIM_00387	7.82e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HBDLGIIM_00388	9.71e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HBDLGIIM_00389	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HBDLGIIM_00390	2.1e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HBDLGIIM_00391	9.09e-280	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HBDLGIIM_00392	8.4e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HBDLGIIM_00393	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HBDLGIIM_00394	3.84e-234	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HBDLGIIM_00395	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HBDLGIIM_00396	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HBDLGIIM_00397	6.9e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HBDLGIIM_00398	2.4e-192	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBDLGIIM_00399	4.86e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
HBDLGIIM_00400	4.65e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HBDLGIIM_00401	5.17e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HBDLGIIM_00402	2.89e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HBDLGIIM_00403	1.81e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HBDLGIIM_00404	6.94e-200	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBDLGIIM_00405	1.13e-271	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HBDLGIIM_00406	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HBDLGIIM_00408	3.99e-176	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HBDLGIIM_00409	3.16e-178	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HBDLGIIM_00410	1.19e-137	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HBDLGIIM_00411	3.66e-276	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HBDLGIIM_00412	3.92e-159	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBDLGIIM_00413	2.83e-199	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HBDLGIIM_00414	2.71e-120	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HBDLGIIM_00415	1.57e-259	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HBDLGIIM_00416	3.93e-13	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HBDLGIIM_00418	2.98e-190	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HBDLGIIM_00419	1.27e-132	ywqM	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_00420	1.62e-156	-	-	-	E	-	-	-	amino acid
HBDLGIIM_00421	5.75e-38	-	-	-	K	-	-	-	acetyltransferase
HBDLGIIM_00422	9.69e-283	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_00423	1.75e-103	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HBDLGIIM_00424	4.76e-121	-	-	-	S	-	-	-	DinB family
HBDLGIIM_00426	2.8e-188	supH	-	-	S	-	-	-	hydrolase
HBDLGIIM_00427	2.57e-171	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HBDLGIIM_00428	1.88e-145	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HBDLGIIM_00429	4.19e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HBDLGIIM_00430	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_00431	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HBDLGIIM_00432	6.62e-231	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
HBDLGIIM_00433	1.61e-107	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBDLGIIM_00434	1.86e-211	yybE	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_00435	3.34e-149	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_00436	1.82e-71	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_00437	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HBDLGIIM_00438	5.56e-129	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HBDLGIIM_00439	9.01e-121	yrhH	-	-	Q	-	-	-	methyltransferase
HBDLGIIM_00440	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HBDLGIIM_00441	2.29e-182	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HBDLGIIM_00442	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HBDLGIIM_00443	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HBDLGIIM_00444	3.91e-105	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HBDLGIIM_00445	3.31e-47	yrhC	-	-	S	-	-	-	YrhC-like protein
HBDLGIIM_00446	1.53e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HBDLGIIM_00447	7.63e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HBDLGIIM_00448	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBDLGIIM_00449	1.2e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HBDLGIIM_00450	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HBDLGIIM_00451	2.92e-123	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HBDLGIIM_00452	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HBDLGIIM_00453	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HBDLGIIM_00454	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HBDLGIIM_00455	5.4e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HBDLGIIM_00456	2.2e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HBDLGIIM_00457	1.91e-152	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HBDLGIIM_00458	4.03e-243	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBDLGIIM_00459	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HBDLGIIM_00460	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBDLGIIM_00461	1.29e-54	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HBDLGIIM_00462	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBDLGIIM_00463	3.29e-237	yrrI	-	-	S	-	-	-	AI-2E family transporter
HBDLGIIM_00464	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HBDLGIIM_00465	2.58e-188	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HBDLGIIM_00466	1.95e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBDLGIIM_00467	3.1e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBDLGIIM_00468	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HBDLGIIM_00469	8.4e-42	yrzR	-	-	-	-	-	-	-
HBDLGIIM_00470	1.76e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_00471	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HBDLGIIM_00472	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HBDLGIIM_00473	3.55e-282	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HBDLGIIM_00474	2.56e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HBDLGIIM_00475	9.19e-84	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_00476	2.07e-300	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HBDLGIIM_00477	3.96e-177	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HBDLGIIM_00478	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HBDLGIIM_00479	1.37e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HBDLGIIM_00482	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HBDLGIIM_00483	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HBDLGIIM_00484	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBDLGIIM_00485	5.1e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HBDLGIIM_00486	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HBDLGIIM_00487	7.78e-63	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HBDLGIIM_00488	2.65e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HBDLGIIM_00489	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBDLGIIM_00490	3.45e-68	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HBDLGIIM_00491	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBDLGIIM_00492	1.95e-141	yrbG	-	-	S	-	-	-	membrane
HBDLGIIM_00493	9.08e-81	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HBDLGIIM_00494	2.09e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HBDLGIIM_00495	8.2e-293	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HBDLGIIM_00496	2.36e-245	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HBDLGIIM_00497	9.76e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HBDLGIIM_00498	3.57e-236	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HBDLGIIM_00499	5.49e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HBDLGIIM_00500	1.03e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HBDLGIIM_00502	8.92e-61	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HBDLGIIM_00503	5.42e-251	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HBDLGIIM_00504	1.12e-267	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HBDLGIIM_00505	2.6e-196	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HBDLGIIM_00506	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HBDLGIIM_00507	3.17e-282	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HBDLGIIM_00508	2.49e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HBDLGIIM_00509	9.52e-205	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HBDLGIIM_00510	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HBDLGIIM_00511	7.1e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HBDLGIIM_00512	7.06e-138	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HBDLGIIM_00513	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HBDLGIIM_00514	1.42e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HBDLGIIM_00515	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HBDLGIIM_00516	1.03e-205	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HBDLGIIM_00517	4.65e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HBDLGIIM_00518	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HBDLGIIM_00519	6.85e-155	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HBDLGIIM_00520	1.76e-110	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HBDLGIIM_00521	4.34e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HBDLGIIM_00522	1.06e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HBDLGIIM_00523	7.5e-65	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HBDLGIIM_00524	1.35e-127	-	-	-	-	-	-	-	-
HBDLGIIM_00526	8.17e-31	-	-	-	-	-	-	-	-
HBDLGIIM_00530	1.15e-159	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HBDLGIIM_00531	1.36e-77	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
HBDLGIIM_00534	4.32e-217	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HBDLGIIM_00535	0.0	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HBDLGIIM_00536	2.41e-290	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HBDLGIIM_00537	7.98e-141	-	-	-	S	-	-	-	Phage tail protein
HBDLGIIM_00538	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HBDLGIIM_00539	1.78e-16	-	-	-	-	-	-	-	-
HBDLGIIM_00540	5.76e-32	-	-	-	-	-	-	-	-
HBDLGIIM_00541	5.11e-76	-	-	-	-	-	-	-	-
HBDLGIIM_00542	1.42e-40	-	-	-	-	-	-	-	-
HBDLGIIM_00543	8.87e-62	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HBDLGIIM_00544	3.08e-20	-	-	-	S	-	-	-	Phage head-tail joining protein
HBDLGIIM_00545	2.86e-31	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HBDLGIIM_00546	3.09e-62	-	-	-	S	-	-	-	peptidoglycan catabolic process
HBDLGIIM_00547	7.43e-09	-	-	-	-	-	-	-	-
HBDLGIIM_00548	8.05e-226	-	-	-	S	-	-	-	capsid protein
HBDLGIIM_00549	2.5e-139	-	-	-	S	-	-	-	peptidase activity
HBDLGIIM_00550	2.44e-305	-	-	-	S	-	-	-	Phage portal protein
HBDLGIIM_00551	1.56e-14	-	-	-	-	-	-	-	-
HBDLGIIM_00552	4.53e-290	-	-	-	S	-	-	-	Phage Terminase
HBDLGIIM_00553	2.34e-113	-	-	-	S	-	-	-	Phage terminase, small subunit
HBDLGIIM_00554	9.5e-94	-	-	-	S	-	-	-	HNH endonuclease
HBDLGIIM_00556	8.89e-27	-	-	-	N	-	-	-	PFAM YcfA family protein
HBDLGIIM_00557	1.7e-96	-	-	-	S	-	-	-	regulation of transcription, DNA-dependent
HBDLGIIM_00559	2.62e-78	-	-	-	-	-	-	-	-
HBDLGIIM_00561	6.12e-106	-	-	-	-	-	-	-	-
HBDLGIIM_00562	2.3e-123	-	-	-	S	-	-	-	nuclease activity
HBDLGIIM_00563	7.89e-69	-	-	-	-	-	-	-	-
HBDLGIIM_00564	0.0	-	-	-	S	-	-	-	hydrolase activity
HBDLGIIM_00565	1.17e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HBDLGIIM_00566	4.58e-07	-	-	-	-	-	-	-	-
HBDLGIIM_00567	4.08e-219	-	-	-	S	-	-	-	AAA domain
HBDLGIIM_00568	3.62e-118	-	-	-	S	-	-	-	DNA protection
HBDLGIIM_00570	1.8e-32	-	-	-	S	-	-	-	Uncharacterized protein YqaH
HBDLGIIM_00573	5.7e-13	-	-	-	K	-	-	-	helix-turn-helix
HBDLGIIM_00574	3.5e-86	-	-	-	S	-	-	-	sequence-specific DNA binding
HBDLGIIM_00575	6.48e-99	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HBDLGIIM_00576	0.0	-	-	-	S	-	-	-	Recombinase
HBDLGIIM_00577	8.68e-90	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HBDLGIIM_00578	3.36e-130	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HBDLGIIM_00579	1.54e-209	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HBDLGIIM_00580	1.81e-171	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HBDLGIIM_00581	1.32e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HBDLGIIM_00582	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HBDLGIIM_00583	1.53e-35	-	-	-	-	-	-	-	-
HBDLGIIM_00584	3.14e-250	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBDLGIIM_00585	8.01e-296	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HBDLGIIM_00586	3.8e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HBDLGIIM_00587	1.2e-236	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HBDLGIIM_00588	3.27e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HBDLGIIM_00589	5.19e-223	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HBDLGIIM_00590	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HBDLGIIM_00591	4.36e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HBDLGIIM_00592	1.13e-113	ysxD	-	-	-	-	-	-	-
HBDLGIIM_00593	3.1e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HBDLGIIM_00594	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HBDLGIIM_00595	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HBDLGIIM_00596	3.83e-295	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HBDLGIIM_00597	2.18e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HBDLGIIM_00598	1.35e-240	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HBDLGIIM_00599	3.77e-150	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HBDLGIIM_00600	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HBDLGIIM_00601	1.23e-254	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HBDLGIIM_00602	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBDLGIIM_00603	6.75e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HBDLGIIM_00604	2.06e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HBDLGIIM_00605	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HBDLGIIM_00608	3.33e-33	-	-	-	-	-	-	-	-
HBDLGIIM_00609	1.38e-100	res	-	-	L	-	-	-	Resolvase, N terminal domain
HBDLGIIM_00610	6.46e-149	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HBDLGIIM_00611	2.31e-313	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
HBDLGIIM_00612	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HBDLGIIM_00614	4.15e-71	-	-	-	L	-	-	-	Phage integrase family
HBDLGIIM_00617	1.52e-114	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HBDLGIIM_00618	1.59e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HBDLGIIM_00619	5.85e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HBDLGIIM_00620	4.47e-255	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HBDLGIIM_00621	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HBDLGIIM_00622	2.18e-96	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_00623	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_00624	2.67e-101	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HBDLGIIM_00625	4.34e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HBDLGIIM_00626	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HBDLGIIM_00627	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HBDLGIIM_00628	2.45e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HBDLGIIM_00629	7.09e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HBDLGIIM_00630	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HBDLGIIM_00631	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HBDLGIIM_00632	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HBDLGIIM_00633	9.67e-225	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HBDLGIIM_00634	8.64e-178	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HBDLGIIM_00635	1.67e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HBDLGIIM_00636	6.22e-134	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_00637	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HBDLGIIM_00638	6.12e-155	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HBDLGIIM_00639	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HBDLGIIM_00640	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HBDLGIIM_00641	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HBDLGIIM_00642	2.87e-107	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HBDLGIIM_00643	1.47e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HBDLGIIM_00644	1.53e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBDLGIIM_00645	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBDLGIIM_00646	1.54e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HBDLGIIM_00647	7.07e-168	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBDLGIIM_00648	1.07e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HBDLGIIM_00649	1.45e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HBDLGIIM_00650	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
HBDLGIIM_00651	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HBDLGIIM_00652	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HBDLGIIM_00653	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HBDLGIIM_00654	1.38e-190	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HBDLGIIM_00655	1.78e-214	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HBDLGIIM_00656	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HBDLGIIM_00657	1.58e-283	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HBDLGIIM_00658	7.52e-182	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HBDLGIIM_00659	3.43e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HBDLGIIM_00660	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HBDLGIIM_00661	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HBDLGIIM_00662	1.71e-241	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HBDLGIIM_00663	1.85e-263	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HBDLGIIM_00664	5.41e-87	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HBDLGIIM_00665	5.44e-56	ysdA	-	-	S	-	-	-	Membrane
HBDLGIIM_00666	2.3e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HBDLGIIM_00667	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HBDLGIIM_00668	1.79e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HBDLGIIM_00669	3.1e-147	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HBDLGIIM_00670	2.76e-69	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
HBDLGIIM_00671	1.05e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HBDLGIIM_00672	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_00673	7.21e-194	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HBDLGIIM_00674	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBDLGIIM_00675	1.34e-195	ytxC	-	-	S	-	-	-	YtxC-like family
HBDLGIIM_00676	5.42e-141	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HBDLGIIM_00677	1.42e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HBDLGIIM_00678	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HBDLGIIM_00679	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HBDLGIIM_00680	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HBDLGIIM_00681	8.93e-249	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HBDLGIIM_00682	1.69e-89	ytcD	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_00683	6.86e-260	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HBDLGIIM_00684	4.54e-205	ytbE	-	-	S	-	-	-	reductase
HBDLGIIM_00685	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBDLGIIM_00686	4.04e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HBDLGIIM_00687	1.64e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HBDLGIIM_00688	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBDLGIIM_00689	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HBDLGIIM_00690	2.9e-167	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_00691	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HBDLGIIM_00692	1.32e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HBDLGIIM_00693	8.21e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HBDLGIIM_00694	2.17e-131	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HBDLGIIM_00695	5.25e-182	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
HBDLGIIM_00697	9.12e-82	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HBDLGIIM_00698	5.65e-96	ytwI	-	-	S	-	-	-	membrane
HBDLGIIM_00699	9.96e-248	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HBDLGIIM_00700	1.39e-83	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HBDLGIIM_00701	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HBDLGIIM_00702	3.98e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HBDLGIIM_00703	2.7e-231	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HBDLGIIM_00704	2.95e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HBDLGIIM_00705	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HBDLGIIM_00706	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HBDLGIIM_00707	4.94e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HBDLGIIM_00708	2.64e-114	ytrI	-	-	-	-	-	-	-
HBDLGIIM_00709	2.45e-32	-	-	-	-	-	-	-	-
HBDLGIIM_00710	2.14e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HBDLGIIM_00711	1.24e-62	ytpI	-	-	S	-	-	-	YtpI-like protein
HBDLGIIM_00712	1.94e-304	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HBDLGIIM_00713	4.86e-165	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HBDLGIIM_00714	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBDLGIIM_00716	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HBDLGIIM_00717	3.03e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HBDLGIIM_00718	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HBDLGIIM_00719	3.16e-279	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBDLGIIM_00720	9.77e-231	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HBDLGIIM_00721	1.36e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HBDLGIIM_00722	4.77e-100	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HBDLGIIM_00723	1.53e-148	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HBDLGIIM_00724	1.6e-113	yteJ	-	-	S	-	-	-	RDD family
HBDLGIIM_00725	6.39e-235	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HBDLGIIM_00726	9.45e-196	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBDLGIIM_00727	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HBDLGIIM_00728	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HBDLGIIM_00729	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HBDLGIIM_00730	2.44e-286	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBDLGIIM_00731	4.75e-267	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HBDLGIIM_00732	1.96e-308	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HBDLGIIM_00733	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HBDLGIIM_00734	1.46e-196	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HBDLGIIM_00735	2.41e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_00736	5.2e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HBDLGIIM_00737	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HBDLGIIM_00738	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HBDLGIIM_00739	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HBDLGIIM_00740	4.11e-129	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HBDLGIIM_00741	3.46e-47	-	-	-	V	-	-	-	HNH endonuclease
HBDLGIIM_00745	7.73e-61	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HBDLGIIM_00747	4.54e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBDLGIIM_00749	1.36e-117	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HBDLGIIM_00751	2.39e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HBDLGIIM_00752	1.74e-193	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBDLGIIM_00753	7.76e-191	-	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_00754	2.86e-160	ygaZ	-	-	E	-	-	-	AzlC protein
HBDLGIIM_00755	3.06e-64	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HBDLGIIM_00756	5.98e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBDLGIIM_00757	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HBDLGIIM_00758	2.84e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HBDLGIIM_00759	4.16e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HBDLGIIM_00760	6.76e-291	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HBDLGIIM_00761	1.05e-155	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HBDLGIIM_00762	5.2e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HBDLGIIM_00763	5.91e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HBDLGIIM_00764	1.54e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HBDLGIIM_00765	5.9e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HBDLGIIM_00766	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HBDLGIIM_00767	5.38e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HBDLGIIM_00768	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HBDLGIIM_00769	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HBDLGIIM_00770	2.08e-139	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBDLGIIM_00771	1.69e-190	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HBDLGIIM_00772	5.47e-76	ytpP	-	-	CO	-	-	-	Thioredoxin
HBDLGIIM_00773	5.77e-102	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HBDLGIIM_00774	6.15e-260	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HBDLGIIM_00775	1.42e-68	ytzB	-	-	S	-	-	-	small secreted protein
HBDLGIIM_00776	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HBDLGIIM_00777	6.76e-212	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HBDLGIIM_00778	6.43e-160	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HBDLGIIM_00779	3.88e-60	ytzH	-	-	S	-	-	-	YtzH-like protein
HBDLGIIM_00780	2.93e-199	ytmP	-	-	M	-	-	-	Phosphotransferase
HBDLGIIM_00781	1.68e-226	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HBDLGIIM_00782	6e-216	ytlQ	-	-	-	-	-	-	-
HBDLGIIM_00783	3.14e-132	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HBDLGIIM_00784	3.37e-222	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HBDLGIIM_00785	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HBDLGIIM_00786	2.99e-290	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HBDLGIIM_00787	2.13e-277	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HBDLGIIM_00788	3.14e-164	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HBDLGIIM_00789	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HBDLGIIM_00790	8.68e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HBDLGIIM_00791	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBDLGIIM_00792	7.53e-299	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HBDLGIIM_00793	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HBDLGIIM_00794	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HBDLGIIM_00795	5.5e-239	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_00796	4.52e-248	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HBDLGIIM_00797	1.87e-216	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBDLGIIM_00798	1.67e-183	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HBDLGIIM_00799	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HBDLGIIM_00800	4.86e-111	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HBDLGIIM_00801	1.74e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
HBDLGIIM_00802	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HBDLGIIM_00803	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HBDLGIIM_00804	5.06e-176	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HBDLGIIM_00805	7.89e-213	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HBDLGIIM_00806	4.67e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
HBDLGIIM_00807	3.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HBDLGIIM_00808	1.39e-111	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HBDLGIIM_00809	5.64e-313	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HBDLGIIM_00810	9.11e-240	ygaE	-	-	S	-	-	-	Membrane
HBDLGIIM_00811	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HBDLGIIM_00812	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HBDLGIIM_00813	5.69e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HBDLGIIM_00814	7.33e-07	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HBDLGIIM_00815	3.81e-173	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBDLGIIM_00816	2.54e-50	yfhS	-	-	-	-	-	-	-
HBDLGIIM_00817	1.78e-263	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HBDLGIIM_00818	1.98e-234	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HBDLGIIM_00819	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HBDLGIIM_00820	1.35e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBDLGIIM_00821	3.23e-217	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HBDLGIIM_00822	1.73e-56	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HBDLGIIM_00823	5.69e-122	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HBDLGIIM_00824	7.37e-59	yfhJ	-	-	S	-	-	-	WVELL protein
HBDLGIIM_00825	9.99e-216	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HBDLGIIM_00827	4.06e-268	yfhI	-	-	EGP	-	-	-	-transporter
HBDLGIIM_00828	1.12e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HBDLGIIM_00829	8.63e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HBDLGIIM_00830	1.04e-215	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HBDLGIIM_00832	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
HBDLGIIM_00833	8.22e-138	yfhC	-	-	C	-	-	-	nitroreductase
HBDLGIIM_00834	6.96e-207	yfhB	-	-	S	-	-	-	PhzF family
HBDLGIIM_00835	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBDLGIIM_00836	2.29e-107	yfiV	-	-	K	-	-	-	transcriptional
HBDLGIIM_00837	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HBDLGIIM_00838	1.05e-73	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HBDLGIIM_00839	3.27e-36	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HBDLGIIM_00840	2.36e-60	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HBDLGIIM_00841	0.0	-	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HBDLGIIM_00842	2.2e-235	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HBDLGIIM_00843	1.79e-144	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HBDLGIIM_00844	4.62e-125	padR	-	-	K	-	-	-	transcriptional
HBDLGIIM_00845	1.46e-214	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HBDLGIIM_00846	2.73e-204	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HBDLGIIM_00847	1.36e-82	yfiD3	-	-	S	-	-	-	DoxX
HBDLGIIM_00848	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HBDLGIIM_00849	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HBDLGIIM_00850	0.0	-	-	-	M	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HBDLGIIM_00851	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_00852	1.82e-177	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HBDLGIIM_00853	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HBDLGIIM_00854	6.64e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HBDLGIIM_00855	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HBDLGIIM_00856	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HBDLGIIM_00857	3.79e-272	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HBDLGIIM_00858	3.08e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HBDLGIIM_00859	1.31e-242	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HBDLGIIM_00860	7.48e-114	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HBDLGIIM_00861	4.93e-244	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBDLGIIM_00862	6.96e-64	-	-	-	S	-	-	-	YfzA-like protein
HBDLGIIM_00863	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBDLGIIM_00864	1.65e-206	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HBDLGIIM_00865	2.5e-233	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HBDLGIIM_00867	7.65e-191	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HBDLGIIM_00868	4.36e-199	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HBDLGIIM_00869	7.99e-37	yfjT	-	-	-	-	-	-	-
HBDLGIIM_00870	2.4e-281	yfkA	-	-	S	-	-	-	YfkB-like domain
HBDLGIIM_00871	1.23e-187	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HBDLGIIM_00872	9.38e-185	yfkD	-	-	S	-	-	-	YfkD-like protein
HBDLGIIM_00873	2.31e-236	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HBDLGIIM_00874	4.15e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_00875	1.37e-12	-	-	-	-	-	-	-	-
HBDLGIIM_00876	3.22e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HBDLGIIM_00877	3.7e-70	yfkI	-	-	S	-	-	-	gas vesicle protein
HBDLGIIM_00878	6.88e-112	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBDLGIIM_00879	1.47e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HBDLGIIM_00880	5.73e-251	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_00881	6.81e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HBDLGIIM_00882	3.54e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HBDLGIIM_00883	1.51e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HBDLGIIM_00884	3.19e-117	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HBDLGIIM_00885	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HBDLGIIM_00886	4.26e-253	yibE	-	-	S	-	-	-	YibE/F-like protein
HBDLGIIM_00887	1.72e-166	yibF	-	-	S	-	-	-	YibE/F-like protein
HBDLGIIM_00888	1.02e-158	frp	-	-	C	-	-	-	nitroreductase
HBDLGIIM_00889	1.13e-163	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HBDLGIIM_00890	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HBDLGIIM_00891	9.06e-313	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_00892	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HBDLGIIM_00893	8.17e-52	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HBDLGIIM_00894	1.43e-104	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HBDLGIIM_00895	2.43e-83	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HBDLGIIM_00896	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HBDLGIIM_00897	2.86e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HBDLGIIM_00898	5.92e-313	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HBDLGIIM_00899	9.02e-176	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HBDLGIIM_00900	1.67e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HBDLGIIM_00901	1.98e-26	yflI	-	-	-	-	-	-	-
HBDLGIIM_00902	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HBDLGIIM_00903	9.82e-156	yflK	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_00904	2.76e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HBDLGIIM_00905	2.47e-278	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HBDLGIIM_00906	1.4e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HBDLGIIM_00907	5.77e-287	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HBDLGIIM_00908	1.18e-227	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HBDLGIIM_00909	3.96e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HBDLGIIM_00910	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HBDLGIIM_00911	1.12e-103	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HBDLGIIM_00912	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HBDLGIIM_00913	5.02e-193	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HBDLGIIM_00914	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
HBDLGIIM_00915	2.34e-93	M1-820	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
HBDLGIIM_00919	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HBDLGIIM_00920	2.76e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HBDLGIIM_00921	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HBDLGIIM_00922	7.35e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HBDLGIIM_00923	5.73e-240	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HBDLGIIM_00924	2.82e-84	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
HBDLGIIM_00925	2.08e-263	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HBDLGIIM_00926	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HBDLGIIM_00927	1.25e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HBDLGIIM_00928	8.7e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HBDLGIIM_00929	1.1e-89	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HBDLGIIM_00930	7.81e-12	-	-	-	C	ko:K15468	-	ko00000,ko01008	Cytochrome P450
HBDLGIIM_00931	5.16e-144	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HBDLGIIM_00932	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HBDLGIIM_00933	1.2e-265	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBDLGIIM_00934	1.3e-181	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HBDLGIIM_00935	5.07e-156	yfmS	-	-	NT	-	-	-	chemotaxis protein
HBDLGIIM_00936	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HBDLGIIM_00937	8.39e-313	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HBDLGIIM_00938	1.1e-277	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_00939	1.99e-238	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HBDLGIIM_00940	1.34e-280	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HBDLGIIM_00941	6.61e-230	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HBDLGIIM_00942	1.32e-217	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HBDLGIIM_00943	3.57e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HBDLGIIM_00944	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HBDLGIIM_00945	7.47e-07	-	-	-	S	-	-	-	protein homooligomerization
HBDLGIIM_00946	5.34e-162	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HBDLGIIM_00947	8.48e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HBDLGIIM_00948	1.67e-66	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HBDLGIIM_00950	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HBDLGIIM_00951	1.38e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HBDLGIIM_00952	2.45e-264	yetM	-	-	CH	-	-	-	FAD binding domain
HBDLGIIM_00953	2.08e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_00954	2.19e-136	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HBDLGIIM_00955	1.82e-73	-	-	-	H	-	-	-	riboflavin kinase activity
HBDLGIIM_00956	1.34e-31	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HBDLGIIM_00957	2.4e-166	cysA	3.6.3.25	-	P	ko:K02045	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HBDLGIIM_00958	1.7e-134	cysW	-	-	P	ko:K02047	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG4208 ABC-type sulfate transport system, permease component
HBDLGIIM_00959	4.82e-142	cysT	-	-	O	ko:K02046	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0555 ABC-type sulfate transport system, permease component
HBDLGIIM_00960	8.82e-10	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG1613 ABC-type sulfate transport system, periplasmic component
HBDLGIIM_00961	3.82e-148	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG1613 ABC-type sulfate transport system, periplasmic component
HBDLGIIM_00962	6.02e-195	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HBDLGIIM_00963	1.32e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBDLGIIM_00964	1.11e-72	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HBDLGIIM_00965	4.99e-154	yetF	-	-	S	-	-	-	membrane
HBDLGIIM_00966	0.00012	-	-	-	-	-	-	-	-
HBDLGIIM_00967	4.48e-120	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HBDLGIIM_00968	1.48e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HBDLGIIM_00969	1.62e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HBDLGIIM_00970	2.67e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HBDLGIIM_00971	1.97e-138	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HBDLGIIM_00974	3.12e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HBDLGIIM_00975	1.18e-307	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HBDLGIIM_00977	3.79e-311	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HBDLGIIM_00978	2.81e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HBDLGIIM_00979	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_00980	6.53e-171	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HBDLGIIM_00981	7.08e-187	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HBDLGIIM_00982	7.39e-226	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBDLGIIM_00983	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HBDLGIIM_00984	1.91e-156	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HBDLGIIM_00985	8.04e-277	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_00986	1.63e-156	-	-	-	K	-	-	-	Collagen triple helix repeat
HBDLGIIM_00987	1.67e-273	-	-	-	M	-	-	-	Glycosyl transferase family 2
HBDLGIIM_00989	7.06e-78	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HBDLGIIM_00990	3.88e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HBDLGIIM_00991	7.24e-113	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HBDLGIIM_00992	6.87e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HBDLGIIM_00993	1.37e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HBDLGIIM_00994	1.77e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HBDLGIIM_00995	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HBDLGIIM_00996	1.04e-65	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HBDLGIIM_00997	4.09e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HBDLGIIM_00998	1.82e-130	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HBDLGIIM_00999	1.46e-118	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HBDLGIIM_01000	6.95e-203	ykgA	-	-	E	-	-	-	Amidinotransferase
HBDLGIIM_01001	1.46e-263	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HBDLGIIM_01002	6.62e-231	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_01003	1.04e-215	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HBDLGIIM_01004	2.9e-253	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HBDLGIIM_01005	5.63e-226	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HBDLGIIM_01006	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HBDLGIIM_01007	9.2e-243	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_01008	6.59e-227	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBDLGIIM_01009	2.8e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBDLGIIM_01010	4.36e-200	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HBDLGIIM_01012	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HBDLGIIM_01013	8.37e-273	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBDLGIIM_01015	4.28e-227	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBDLGIIM_01016	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HBDLGIIM_01017	1.23e-55	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HBDLGIIM_01018	1.2e-151	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HBDLGIIM_01019	2.3e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HBDLGIIM_01020	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HBDLGIIM_01021	7.07e-226	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HBDLGIIM_01022	1.89e-172	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HBDLGIIM_01023	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HBDLGIIM_01024	5.16e-217	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HBDLGIIM_01025	4.7e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
HBDLGIIM_01026	3.87e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HBDLGIIM_01027	6.09e-176	xepA	-	-	-	-	-	-	-
HBDLGIIM_01028	3.25e-40	xkdX	-	-	-	-	-	-	-
HBDLGIIM_01030	7.41e-231	-	-	-	-	-	-	-	-
HBDLGIIM_01031	3.63e-37	-	-	-	-	-	-	-	-
HBDLGIIM_01032	4.1e-112	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HBDLGIIM_01033	1.53e-212	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HBDLGIIM_01034	5.77e-76	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HBDLGIIM_01035	5.07e-43	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HBDLGIIM_01036	5.14e-204	xkdQ	-	-	G	-	-	-	NLP P60 protein
HBDLGIIM_01037	2.67e-144	xkdP	-	-	S	-	-	-	Lysin motif
HBDLGIIM_01038	1.6e-281	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HBDLGIIM_01039	4.33e-27	-	-	-	-	-	-	-	-
HBDLGIIM_01040	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HBDLGIIM_01041	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
HBDLGIIM_01042	2.31e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HBDLGIIM_01043	5.92e-20	-	-	-	-	-	-	-	-
HBDLGIIM_01044	3.51e-73	xkdJ	-	-	-	-	-	-	-
HBDLGIIM_01045	9.8e-77	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HBDLGIIM_01046	1.93e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HBDLGIIM_01047	1.78e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HBDLGIIM_01048	8.3e-203	xkdG	-	-	S	-	-	-	Phage capsid family
HBDLGIIM_01049	5.07e-118	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HBDLGIIM_01050	1.79e-302	xkdE3	-	-	S	-	-	-	portal protein
HBDLGIIM_01051	3.9e-262	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HBDLGIIM_01052	1.18e-140	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HBDLGIIM_01053	1.24e-109	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HBDLGIIM_01057	8.78e-196	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HBDLGIIM_01058	0.000156	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
HBDLGIIM_01060	6.52e-75	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HBDLGIIM_01061	1.54e-143	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HBDLGIIM_01063	1.07e-141	yjqB	-	-	S	-	-	-	phage-related replication protein
HBDLGIIM_01064	2.1e-69	yjqA	-	-	S	-	-	-	Bacterial PH domain
HBDLGIIM_01065	1.94e-220	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HBDLGIIM_01067	2.68e-275	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HBDLGIIM_01068	8.38e-103	yjoA	-	-	S	-	-	-	DinB family
HBDLGIIM_01069	3.21e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HBDLGIIM_01070	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HBDLGIIM_01071	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HBDLGIIM_01072	1.02e-234	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HBDLGIIM_01073	2.83e-63	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HBDLGIIM_01074	9.87e-233	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HBDLGIIM_01075	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HBDLGIIM_01076	6.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HBDLGIIM_01077	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HBDLGIIM_01078	1e-117	yjlB	-	-	S	-	-	-	Cupin domain
HBDLGIIM_01079	6.53e-224	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HBDLGIIM_01080	2.26e-168	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_01081	2.42e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HBDLGIIM_01082	1.31e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HBDLGIIM_01083	1.73e-40	-	-	-	-	-	-	-	-
HBDLGIIM_01084	1.03e-286	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HBDLGIIM_01085	2.28e-291	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HBDLGIIM_01086	2.2e-117	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HBDLGIIM_01087	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HBDLGIIM_01088	3.92e-129	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HBDLGIIM_01089	7.32e-91	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HBDLGIIM_01090	1.91e-31	yjfB	-	-	S	-	-	-	Putative motility protein
HBDLGIIM_01092	2.48e-136	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HBDLGIIM_01093	6.88e-68	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_01094	6.86e-46	-	-	-	-	-	-	-	-
HBDLGIIM_01095	2.06e-161	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HBDLGIIM_01096	1.19e-178	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HBDLGIIM_01097	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HBDLGIIM_01098	5.16e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_01099	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBDLGIIM_01100	5.44e-277	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HBDLGIIM_01101	5.74e-240	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBDLGIIM_01102	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HBDLGIIM_01103	6.62e-282	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HBDLGIIM_01104	2.13e-106	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_01105	1.36e-289	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
HBDLGIIM_01106	3.51e-58	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HBDLGIIM_01107	3.32e-210	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HBDLGIIM_01108	1.71e-14	yqaS	-	-	L	-	-	-	DNA packaging
HBDLGIIM_01112	1.3e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2971)
HBDLGIIM_01115	3.25e-96	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
HBDLGIIM_01116	1.02e-63	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HBDLGIIM_01117	1.58e-106	-	-	-	S	-	-	-	Alpha beta hydrolase
HBDLGIIM_01118	3.69e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HBDLGIIM_01119	3e-226	yplP	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_01120	1e-307	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBDLGIIM_01121	8.98e-55	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HBDLGIIM_01122	1.71e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HBDLGIIM_01123	1.49e-175	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HBDLGIIM_01124	3.23e-125	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_01125	9.6e-89	ypoP	-	-	K	-	-	-	transcriptional
HBDLGIIM_01126	1.2e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBDLGIIM_01127	4.61e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HBDLGIIM_01128	1.3e-136	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HBDLGIIM_01129	0.0	yokA	-	-	L	-	-	-	Recombinase
HBDLGIIM_01132	6.83e-107	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HBDLGIIM_01133	3.12e-111	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
HBDLGIIM_01134	8.42e-304	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HBDLGIIM_01135	5.08e-112	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HBDLGIIM_01136	2.32e-94	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HBDLGIIM_01137	1.63e-115	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HBDLGIIM_01139	1.24e-82	-	-	-	S	-	-	-	SMI1 / KNR4 family
HBDLGIIM_01140	5.36e-92	yoaW	-	-	-	-	-	-	-
HBDLGIIM_01146	9.91e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4236)
HBDLGIIM_01147	4.01e-12	-	-	-	K	-	-	-	Putative DNA-binding domain
HBDLGIIM_01148	3.11e-28	-	-	-	K	-	-	-	Putative DNA-binding domain
HBDLGIIM_01152	9.44e-08	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HBDLGIIM_01153	1.04e-314	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HBDLGIIM_01154	1.11e-81	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HBDLGIIM_01157	7.49e-49	-	-	-	S	-	-	-	amine dehydrogenase activity
HBDLGIIM_01158	1.29e-88	-	-	-	S	-	-	-	amine dehydrogenase activity
HBDLGIIM_01159	2.59e-20	-	-	-	S	-	-	-	amine dehydrogenase activity
HBDLGIIM_01161	8.92e-251	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HBDLGIIM_01162	1.85e-99	yoqH	-	-	M	-	-	-	LysM domain
HBDLGIIM_01167	3.54e-95	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HBDLGIIM_01168	1.76e-279	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HBDLGIIM_01169	2.13e-229	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HBDLGIIM_01170	4.09e-86	cgeA	-	-	-	ko:K06319	-	ko00000	-
HBDLGIIM_01171	8.14e-63	cgeC	-	-	-	ko:K06321	-	ko00000	-
HBDLGIIM_01172	9.83e-317	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HBDLGIIM_01173	1.64e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HBDLGIIM_01175	3.4e-83	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
HBDLGIIM_01176	1.69e-312	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBDLGIIM_01177	1.97e-160	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBDLGIIM_01178	3.81e-159	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HBDLGIIM_01179	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HBDLGIIM_01180	3.44e-204	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HBDLGIIM_01181	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HBDLGIIM_01182	8.43e-64	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HBDLGIIM_01183	1e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HBDLGIIM_01184	9.94e-17	-	-	-	E	-	-	-	lactoylglutathione lyase activity
HBDLGIIM_01185	7.75e-161	yodN	-	-	-	-	-	-	-
HBDLGIIM_01187	9.77e-34	yozD	-	-	S	-	-	-	YozD-like protein
HBDLGIIM_01188	6.13e-133	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HBDLGIIM_01189	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
HBDLGIIM_01191	1.05e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HBDLGIIM_01192	6.38e-192	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HBDLGIIM_01193	3.98e-49	yodI	-	-	-	-	-	-	-
HBDLGIIM_01194	1.76e-165	yodH	-	-	Q	-	-	-	Methyltransferase
HBDLGIIM_01195	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HBDLGIIM_01196	2.49e-169	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_01197	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HBDLGIIM_01198	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
HBDLGIIM_01199	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBDLGIIM_01200	1.97e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HBDLGIIM_01201	5.17e-220	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HBDLGIIM_01202	2.84e-139	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HBDLGIIM_01203	1.35e-138	yodC	-	-	C	-	-	-	nitroreductase
HBDLGIIM_01204	2.42e-74	yodB	-	-	K	-	-	-	transcriptional
HBDLGIIM_01205	2.74e-92	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HBDLGIIM_01206	2.59e-89	iolK	-	-	S	-	-	-	tautomerase
HBDLGIIM_01208	4.68e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HBDLGIIM_01209	2e-208	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HBDLGIIM_01210	1.05e-30	-	-	-	-	-	-	-	-
HBDLGIIM_01211	8.09e-80	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HBDLGIIM_01212	1.57e-162	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HBDLGIIM_01213	8.33e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HBDLGIIM_01214	2.79e-309	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HBDLGIIM_01216	1.91e-143	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HBDLGIIM_01217	1.36e-284	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HBDLGIIM_01218	3.94e-291	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HBDLGIIM_01219	2.55e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBDLGIIM_01220	4.2e-209	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HBDLGIIM_01221	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HBDLGIIM_01222	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HBDLGIIM_01223	1.05e-262	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HBDLGIIM_01224	9.06e-180	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HBDLGIIM_01225	1.31e-124	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HBDLGIIM_01226	3.42e-77	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HBDLGIIM_01227	2.41e-297	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HBDLGIIM_01228	1.66e-212	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HBDLGIIM_01229	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HBDLGIIM_01230	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HBDLGIIM_01231	2.72e-42	yozC	-	-	-	-	-	-	-
HBDLGIIM_01233	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
HBDLGIIM_01234	6.36e-50	yocN	-	-	-	-	-	-	-
HBDLGIIM_01235	5.58e-59	yozN	-	-	-	-	-	-	-
HBDLGIIM_01236	1.33e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HBDLGIIM_01237	3.51e-13	yocN	-	-	-	-	-	-	-
HBDLGIIM_01238	3.83e-13	yocL	-	-	-	-	-	-	-
HBDLGIIM_01239	5.24e-78	yocK	-	-	T	-	-	-	general stress protein
HBDLGIIM_01241	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBDLGIIM_01242	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBDLGIIM_01243	9.79e-168	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HBDLGIIM_01245	1.02e-235	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HBDLGIIM_01246	1.6e-123	yocC	-	-	-	-	-	-	-
HBDLGIIM_01247	1.59e-174	-	-	-	J	-	-	-	Protein required for attachment to host cells
HBDLGIIM_01248	8.99e-116	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HBDLGIIM_01249	9.41e-155	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HBDLGIIM_01250	6.33e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HBDLGIIM_01251	3.86e-119	yobW	-	-	-	-	-	-	-
HBDLGIIM_01252	9.81e-175	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HBDLGIIM_01253	1.08e-121	yobS	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_01254	4.85e-169	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HBDLGIIM_01255	3.67e-71	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HBDLGIIM_01258	1.7e-234	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HBDLGIIM_01259	5.22e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HBDLGIIM_01260	1.02e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HBDLGIIM_01261	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HBDLGIIM_01262	9.22e-245	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HBDLGIIM_01263	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HBDLGIIM_01264	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HBDLGIIM_01265	1.06e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HBDLGIIM_01266	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HBDLGIIM_01267	1.92e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HBDLGIIM_01268	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HBDLGIIM_01269	8.26e-165	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HBDLGIIM_01270	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HBDLGIIM_01271	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HBDLGIIM_01272	2.67e-252	-	-	-	D	-	-	-	nuclear chromosome segregation
HBDLGIIM_01273	4.91e-126	-	-	-	-	-	-	-	-
HBDLGIIM_01274	4.25e-273	-	-	-	-	-	-	-	-
HBDLGIIM_01275	5.96e-57	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HBDLGIIM_01276	1.66e-218	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HBDLGIIM_01277	1.79e-41	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HBDLGIIM_01278	6.46e-145	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HBDLGIIM_01279	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBDLGIIM_01280	2.61e-161	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HBDLGIIM_01281	1.86e-222	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HBDLGIIM_01282	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HBDLGIIM_01283	2.79e-193	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HBDLGIIM_01284	1.87e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBDLGIIM_01285	1e-248	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HBDLGIIM_01286	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
HBDLGIIM_01287	6.08e-196	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HBDLGIIM_01289	2.02e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HBDLGIIM_01290	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HBDLGIIM_01291	4.33e-315	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HBDLGIIM_01292	1.44e-197	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBDLGIIM_01293	2.79e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HBDLGIIM_01294	1.25e-265	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HBDLGIIM_01295	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HBDLGIIM_01296	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HBDLGIIM_01297	1.15e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBDLGIIM_01298	3.04e-313	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HBDLGIIM_01299	1.23e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HBDLGIIM_01300	2.26e-170	yebC	-	-	M	-	-	-	Membrane
HBDLGIIM_01302	1.48e-119	yebE	-	-	S	-	-	-	UPF0316 protein
HBDLGIIM_01303	2.21e-38	yebG	-	-	S	-	-	-	NETI protein
HBDLGIIM_01304	1.13e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HBDLGIIM_01305	3.08e-285	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBDLGIIM_01306	8.99e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBDLGIIM_01307	3.53e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HBDLGIIM_01308	1.55e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBDLGIIM_01309	9.46e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBDLGIIM_01310	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBDLGIIM_01311	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HBDLGIIM_01312	4.38e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HBDLGIIM_01313	4.22e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBDLGIIM_01314	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HBDLGIIM_01315	1.63e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HBDLGIIM_01316	1.03e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HBDLGIIM_01317	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HBDLGIIM_01318	2.98e-247	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HBDLGIIM_01319	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_01320	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HBDLGIIM_01321	8.71e-164	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HBDLGIIM_01322	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HBDLGIIM_01323	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HBDLGIIM_01324	4.55e-285	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HBDLGIIM_01325	4.06e-245	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HBDLGIIM_01326	1.18e-157	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HBDLGIIM_01327	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBDLGIIM_01328	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBDLGIIM_01329	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HBDLGIIM_01330	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBDLGIIM_01331	3.85e-198	yerO	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_01332	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBDLGIIM_01333	4.95e-216	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HBDLGIIM_01334	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBDLGIIM_01335	1.56e-186	-	-	-	L	-	-	-	AAA ATPase domain
HBDLGIIM_01337	6.9e-41	-	-	-	S	-	-	-	Colicin immunity protein / pyocin immunity protein
HBDLGIIM_01339	1.25e-102	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HBDLGIIM_01340	3.33e-73	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HBDLGIIM_01341	2.21e-61	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HBDLGIIM_01342	1.82e-27	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HBDLGIIM_01343	2.34e-31	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HBDLGIIM_01344	4.5e-91	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HBDLGIIM_01345	1.59e-28	-	-	-	S	-	-	-	Colicin immunity protein / pyocin immunity protein
HBDLGIIM_01346	3.66e-44	-	-	-	M	-	-	-	RHS protein
HBDLGIIM_01347	2.6e-182	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HBDLGIIM_01348	5.1e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HBDLGIIM_01349	1.95e-102	gerD	-	-	-	ko:K06294	-	ko00000	-
HBDLGIIM_01350	2.21e-254	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HBDLGIIM_01351	1.15e-172	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HBDLGIIM_01352	1.31e-102	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HBDLGIIM_01353	2.13e-106	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
HBDLGIIM_01354	1.76e-185	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HBDLGIIM_01355	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HBDLGIIM_01356	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HBDLGIIM_01357	4.16e-180	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HBDLGIIM_01358	2.77e-178	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBDLGIIM_01359	9.91e-190	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBDLGIIM_01360	8.39e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBDLGIIM_01361	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HBDLGIIM_01362	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBDLGIIM_01363	2.28e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HBDLGIIM_01364	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HBDLGIIM_01365	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HBDLGIIM_01366	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HBDLGIIM_01367	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HBDLGIIM_01368	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HBDLGIIM_01369	1.9e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HBDLGIIM_01370	5.15e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HBDLGIIM_01371	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HBDLGIIM_01372	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HBDLGIIM_01373	8.29e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HBDLGIIM_01374	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HBDLGIIM_01375	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HBDLGIIM_01376	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HBDLGIIM_01377	5.43e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HBDLGIIM_01378	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HBDLGIIM_01379	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HBDLGIIM_01380	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HBDLGIIM_01381	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HBDLGIIM_01382	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HBDLGIIM_01383	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HBDLGIIM_01384	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HBDLGIIM_01385	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HBDLGIIM_01386	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HBDLGIIM_01387	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HBDLGIIM_01388	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HBDLGIIM_01389	1.77e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HBDLGIIM_01390	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HBDLGIIM_01391	1.71e-241	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HBDLGIIM_01392	2.35e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HBDLGIIM_01393	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HBDLGIIM_01394	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HBDLGIIM_01395	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HBDLGIIM_01396	5.94e-46	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HBDLGIIM_01397	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBDLGIIM_01398	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBDLGIIM_01399	2.95e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HBDLGIIM_01400	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HBDLGIIM_01401	2.33e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HBDLGIIM_01402	8.66e-161	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HBDLGIIM_01403	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HBDLGIIM_01404	1.28e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HBDLGIIM_01405	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HBDLGIIM_01406	1.39e-150	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HBDLGIIM_01407	4.03e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HBDLGIIM_01408	1.01e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBDLGIIM_01409	4.11e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HBDLGIIM_01410	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HBDLGIIM_01411	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HBDLGIIM_01412	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBDLGIIM_01413	3.02e-111	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HBDLGIIM_01414	5.61e-157	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HBDLGIIM_01415	8.6e-251	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HBDLGIIM_01416	8.93e-250	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HBDLGIIM_01417	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HBDLGIIM_01418	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HBDLGIIM_01419	4.67e-258	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HBDLGIIM_01420	1.89e-82	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HBDLGIIM_01421	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HBDLGIIM_01422	1.01e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HBDLGIIM_01424	1.08e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HBDLGIIM_01425	1.04e-57	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HBDLGIIM_01427	0.0	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HBDLGIIM_01428	1.94e-47	-	-	-	-	-	-	-	-
HBDLGIIM_01430	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HBDLGIIM_01431	1.16e-284	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HBDLGIIM_01432	6.39e-234	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HBDLGIIM_01433	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HBDLGIIM_01434	9.45e-124	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HBDLGIIM_01435	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HBDLGIIM_01436	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
HBDLGIIM_01437	7.59e-138	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HBDLGIIM_01438	1.85e-178	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HBDLGIIM_01439	1.56e-279	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HBDLGIIM_01440	1.1e-263	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HBDLGIIM_01441	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
HBDLGIIM_01442	9.37e-207	yvdE	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_01443	8.57e-134	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HBDLGIIM_01444	3.08e-68	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HBDLGIIM_01445	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HBDLGIIM_01446	4.41e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HBDLGIIM_01447	2.51e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBDLGIIM_01448	5.54e-105	-	-	-	M	-	-	-	Ribonuclease
HBDLGIIM_01449	5.69e-183	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HBDLGIIM_01450	2.76e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HBDLGIIM_01451	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HBDLGIIM_01452	8.99e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HBDLGIIM_01453	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HBDLGIIM_01454	5.15e-113	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HBDLGIIM_01455	3.13e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HBDLGIIM_01456	7.1e-202	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HBDLGIIM_01457	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HBDLGIIM_01458	3.74e-243	sasA	-	-	T	-	-	-	Histidine kinase
HBDLGIIM_01459	3.99e-158	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_01460	5.51e-73	-	-	-	-	-	-	-	-
HBDLGIIM_01461	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HBDLGIIM_01462	4.7e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HBDLGIIM_01463	1.38e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HBDLGIIM_01464	5.61e-168	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HBDLGIIM_01465	2.82e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HBDLGIIM_01466	3.91e-136	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HBDLGIIM_01467	3.7e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HBDLGIIM_01468	1.83e-148	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HBDLGIIM_01469	4.07e-268	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HBDLGIIM_01470	2.06e-177	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HBDLGIIM_01471	1.46e-111	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HBDLGIIM_01472	1.64e-157	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HBDLGIIM_01473	2.92e-192	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HBDLGIIM_01474	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HBDLGIIM_01475	1.3e-283	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HBDLGIIM_01476	1.1e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HBDLGIIM_01477	1.05e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HBDLGIIM_01478	5.16e-135	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HBDLGIIM_01479	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HBDLGIIM_01480	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBDLGIIM_01481	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBDLGIIM_01482	2.52e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HBDLGIIM_01483	5.3e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HBDLGIIM_01484	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HBDLGIIM_01485	3.45e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HBDLGIIM_01486	5.59e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HBDLGIIM_01487	1.99e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HBDLGIIM_01488	2.12e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBDLGIIM_01489	7.7e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HBDLGIIM_01490	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HBDLGIIM_01491	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HBDLGIIM_01492	2.29e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HBDLGIIM_01493	6.61e-195	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HBDLGIIM_01494	1.23e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HBDLGIIM_01495	1.43e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HBDLGIIM_01496	4.91e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HBDLGIIM_01497	2.56e-55	yhhY	-	-	K	-	-	-	FR47-like protein
HBDLGIIM_01498	2.37e-225	yyaD	-	-	S	-	-	-	Membrane
HBDLGIIM_01499	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_01500	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBDLGIIM_01501	5.42e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HBDLGIIM_01502	2.9e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HBDLGIIM_01503	4.77e-99	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HBDLGIIM_01504	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HBDLGIIM_01505	3.34e-132	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HBDLGIIM_01506	3.85e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBDLGIIM_01507	2.22e-182	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HBDLGIIM_01508	1.62e-230	ccpB	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_01509	3.43e-88	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBDLGIIM_01510	7.51e-316	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HBDLGIIM_01511	2.33e-207	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HBDLGIIM_01512	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HBDLGIIM_01513	2.42e-30	yyaL	-	-	O	ko:K06888	-	ko00000	Highly conserved protein containing a thioredoxin domain
HBDLGIIM_01515	1.28e-55	-	-	-	S	-	-	-	SIR2-like domain
HBDLGIIM_01517	1.21e-34	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HBDLGIIM_01518	3.19e-81	ydcG	-	-	S	-	-	-	EVE domain
HBDLGIIM_01519	2.72e-59	-	-	-	P	-	-	-	Rhodanese Homology Domain
HBDLGIIM_01520	4.84e-83	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_01521	7.99e-35	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HBDLGIIM_01522	1.35e-89	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HBDLGIIM_01523	7.8e-166	-	-	-	EG	-	-	-	EamA-like transporter family
HBDLGIIM_01524	4.31e-316	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBDLGIIM_01525	7.7e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HBDLGIIM_01526	1.52e-98	yybA	-	-	K	-	-	-	transcriptional
HBDLGIIM_01527	3.4e-197	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBDLGIIM_01528	1.95e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HBDLGIIM_01529	4e-147	ydgI	-	-	C	-	-	-	nitroreductase
HBDLGIIM_01530	1.21e-70	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HBDLGIIM_01531	1.29e-102	eamA1	-	-	EG	-	-	-	spore germination
HBDLGIIM_01532	2.34e-204	-	-	-	G	-	-	-	Major Facilitator Superfamily
HBDLGIIM_01533	6.46e-116	-	-	-	S	-	-	-	PFAM DinB family protein
HBDLGIIM_01534	1.09e-148	-	-	-	K	-	-	-	FCD domain
HBDLGIIM_01535	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HBDLGIIM_01536	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HBDLGIIM_01537	1.44e-197	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HBDLGIIM_01538	1.1e-173	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HBDLGIIM_01539	1.46e-239	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HBDLGIIM_01540	3.04e-200	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HBDLGIIM_01541	3.45e-234	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HBDLGIIM_01542	5.47e-178	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HBDLGIIM_01543	1.2e-40	-	-	-	-	-	-	-	-
HBDLGIIM_01544	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HBDLGIIM_01545	4.89e-265	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HBDLGIIM_01546	4.22e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HBDLGIIM_01547	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBDLGIIM_01548	1.85e-284	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HBDLGIIM_01549	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HBDLGIIM_01550	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HBDLGIIM_01551	8.23e-147	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HBDLGIIM_01552	2.82e-185	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HBDLGIIM_01553	4.67e-303	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HBDLGIIM_01554	3.12e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HBDLGIIM_01555	1.9e-230	yvhJ	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_01556	5.93e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HBDLGIIM_01557	3.44e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HBDLGIIM_01558	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBDLGIIM_01559	8.81e-204	degV	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_01560	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HBDLGIIM_01561	5.91e-56	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HBDLGIIM_01563	1.43e-99	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HBDLGIIM_01564	6.4e-97	yvyF	-	-	S	-	-	-	flagellar protein
HBDLGIIM_01565	6.14e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HBDLGIIM_01566	2.2e-105	yvyG	-	-	NOU	-	-	-	FlgN protein
HBDLGIIM_01567	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HBDLGIIM_01568	1.2e-208	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HBDLGIIM_01569	9.36e-107	yviE	-	-	-	-	-	-	-
HBDLGIIM_01570	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HBDLGIIM_01571	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HBDLGIIM_01572	1.21e-152	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBDLGIIM_01573	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HBDLGIIM_01574	5.79e-88	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HBDLGIIM_01575	7.78e-11	fliT	-	-	N	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HBDLGIIM_01576	3.87e-89	-	-	-	-	-	-	-	-
HBDLGIIM_01577	3.94e-133	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HBDLGIIM_01578	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HBDLGIIM_01579	5.45e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HBDLGIIM_01580	6.85e-192	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBDLGIIM_01581	3.08e-60	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HBDLGIIM_01582	8.68e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HBDLGIIM_01583	7.34e-197	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HBDLGIIM_01584	4.04e-303	ywoF	-	-	P	-	-	-	Right handed beta helix region
HBDLGIIM_01585	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HBDLGIIM_01586	2.47e-73	swrA	-	-	S	-	-	-	Swarming motility protein
HBDLGIIM_01587	8.77e-282	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBDLGIIM_01588	7.88e-20	-	-	-	L	ko:K07497	-	ko00000	transposition
HBDLGIIM_01590	2.01e-69	-	-	-	IQ	-	-	-	KR domain
HBDLGIIM_01591	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HBDLGIIM_01592	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBDLGIIM_01593	6.1e-40	yazB	-	-	K	-	-	-	transcriptional
HBDLGIIM_01594	8.2e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBDLGIIM_01595	4.62e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HBDLGIIM_01596	5.07e-200	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBDLGIIM_01597	6.68e-205	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HBDLGIIM_01598	5.35e-139	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HBDLGIIM_01599	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBDLGIIM_01600	8.88e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HBDLGIIM_01601	2.39e-199	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HBDLGIIM_01602	3.19e-206	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBDLGIIM_01603	1.34e-186	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HBDLGIIM_01604	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBDLGIIM_01605	1.05e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HBDLGIIM_01606	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HBDLGIIM_01607	6.66e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HBDLGIIM_01608	3.79e-166	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HBDLGIIM_01609	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HBDLGIIM_01612	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HBDLGIIM_01613	1.7e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HBDLGIIM_01614	1.13e-132	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HBDLGIIM_01615	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HBDLGIIM_01616	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HBDLGIIM_01617	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HBDLGIIM_01618	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBDLGIIM_01619	8.02e-119	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HBDLGIIM_01620	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBDLGIIM_01621	1.1e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HBDLGIIM_01622	2.89e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HBDLGIIM_01623	6.18e-137	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HBDLGIIM_01624	2.47e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBDLGIIM_01625	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HBDLGIIM_01626	8.55e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HBDLGIIM_01627	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HBDLGIIM_01628	5.67e-197	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HBDLGIIM_01629	2.25e-205	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HBDLGIIM_01630	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HBDLGIIM_01631	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_01632	1.41e-209	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HBDLGIIM_01633	2.07e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HBDLGIIM_01634	7.62e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HBDLGIIM_01635	2.49e-310	yabE	-	-	T	-	-	-	protein conserved in bacteria
HBDLGIIM_01636	5.87e-182	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HBDLGIIM_01637	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBDLGIIM_01638	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HBDLGIIM_01639	7.84e-208	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HBDLGIIM_01640	6.96e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HBDLGIIM_01641	3.99e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HBDLGIIM_01642	3.08e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HBDLGIIM_01643	9e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HBDLGIIM_01644	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HBDLGIIM_01645	2.98e-94	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HBDLGIIM_01646	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_01647	1.9e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HBDLGIIM_01648	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HBDLGIIM_01649	1.99e-243	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HBDLGIIM_01650	5.06e-137	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HBDLGIIM_01651	4.46e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HBDLGIIM_01652	1.12e-267	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HBDLGIIM_01653	2.29e-164	ywaF	-	-	S	-	-	-	Integral membrane protein
HBDLGIIM_01654	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HBDLGIIM_01655	2.2e-172	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_01656	3.25e-217	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HBDLGIIM_01657	6.38e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_01658	9.58e-288	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HBDLGIIM_01659	2.12e-161	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_01660	1.66e-205	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HBDLGIIM_01661	3.41e-231	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HBDLGIIM_01662	6.48e-220	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HBDLGIIM_01663	5.11e-208	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_01664	5.41e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HBDLGIIM_01665	7.09e-53	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HBDLGIIM_01666	5.15e-246	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HBDLGIIM_01667	0.0	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_01668	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HBDLGIIM_01669	1.26e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HBDLGIIM_01671	2.12e-184	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
HBDLGIIM_01672	2.87e-271	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HBDLGIIM_01673	6.95e-194	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HBDLGIIM_01674	3.33e-83	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBDLGIIM_01675	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HBDLGIIM_01676	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HBDLGIIM_01677	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HBDLGIIM_01678	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HBDLGIIM_01679	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HBDLGIIM_01680	7.79e-190	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HBDLGIIM_01681	6.17e-237	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HBDLGIIM_01682	6.12e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HBDLGIIM_01683	7.34e-181	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HBDLGIIM_01684	1.01e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HBDLGIIM_01685	1.23e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HBDLGIIM_01686	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HBDLGIIM_01688	1.48e-99	ytkA	-	-	S	-	-	-	YtkA-like
HBDLGIIM_01689	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HBDLGIIM_01690	8.41e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HBDLGIIM_01691	9.31e-137	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HBDLGIIM_01692	7.13e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HBDLGIIM_01693	1.82e-312	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HBDLGIIM_01694	1.74e-232	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HBDLGIIM_01695	1.92e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HBDLGIIM_01696	1.23e-158	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HBDLGIIM_01697	4.42e-203	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HBDLGIIM_01698	4.48e-156	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HBDLGIIM_01699	3.57e-162	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HBDLGIIM_01700	1.37e-270	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HBDLGIIM_01701	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HBDLGIIM_01702	6.18e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HBDLGIIM_01703	9.15e-198	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HBDLGIIM_01704	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HBDLGIIM_01705	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HBDLGIIM_01706	3.03e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HBDLGIIM_01707	6.1e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HBDLGIIM_01714	3.74e-83	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HBDLGIIM_01715	4.75e-119	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
HBDLGIIM_01716	0.0	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HBDLGIIM_01717	4.66e-243	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HBDLGIIM_01718	0.0	-	-	-	-	-	-	-	-
HBDLGIIM_01719	4.27e-257	-	-	-	S	-	-	-	Major Facilitator Superfamily
HBDLGIIM_01720	0.0	-	-	-	S	-	-	-	ABC transporter
HBDLGIIM_01721	4.53e-189	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
HBDLGIIM_01722	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HBDLGIIM_01723	2.69e-57	sdpR	-	-	K	-	-	-	transcriptional
HBDLGIIM_01724	1.69e-83	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HBDLGIIM_01725	6.81e-295	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HBDLGIIM_01726	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HBDLGIIM_01727	1.86e-212	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HBDLGIIM_01728	1.11e-260	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HBDLGIIM_01730	2.05e-113	yycN	-	-	K	-	-	-	Acetyltransferase
HBDLGIIM_01731	3.04e-233	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HBDLGIIM_01732	8.3e-172	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HBDLGIIM_01733	2.81e-278	yycP	-	-	-	-	-	-	-
HBDLGIIM_01736	8.3e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HBDLGIIM_01737	2.01e-245	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HBDLGIIM_01739	2.34e-27	-	-	-	-	-	-	-	-
HBDLGIIM_01740	3.16e-234	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HBDLGIIM_01741	2.07e-237	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HBDLGIIM_01742	9.82e-115	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HBDLGIIM_01743	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HBDLGIIM_01744	6.65e-198	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HBDLGIIM_01745	4.92e-110	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HBDLGIIM_01746	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HBDLGIIM_01747	3.04e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HBDLGIIM_01748	7.64e-290	-	-	-	S	-	-	-	Fic/DOC family
HBDLGIIM_01749	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HBDLGIIM_01750	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HBDLGIIM_01751	4.48e-161	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
HBDLGIIM_01752	7.8e-97	yxaI	-	-	S	-	-	-	membrane protein domain
HBDLGIIM_01753	7.39e-84	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HBDLGIIM_01754	1.34e-111	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HBDLGIIM_01755	2.01e-66	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HBDLGIIM_01756	8.36e-84	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HBDLGIIM_01757	1.5e-190	yxaL	-	-	S	-	-	-	PQQ-like domain
HBDLGIIM_01758	0.0	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HBDLGIIM_01759	1.09e-274	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HBDLGIIM_01760	1.68e-253	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HBDLGIIM_01761	4.6e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_01762	2.62e-132	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBDLGIIM_01763	3.56e-194	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HBDLGIIM_01765	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HBDLGIIM_01766	3.17e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBDLGIIM_01767	1.43e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HBDLGIIM_01768	6.09e-175	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HBDLGIIM_01769	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HBDLGIIM_01770	5.96e-201	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HBDLGIIM_01771	2.8e-231	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HBDLGIIM_01772	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HBDLGIIM_01773	2.79e-224	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HBDLGIIM_01774	2.59e-294	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HBDLGIIM_01775	4.26e-249	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HBDLGIIM_01776	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HBDLGIIM_01777	3.58e-202	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HBDLGIIM_01778	1.4e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HBDLGIIM_01779	5.65e-160	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_01780	7.95e-224	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_01781	2.57e-20	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_01782	1.81e-112	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_01783	4.32e-56	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_01784	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HBDLGIIM_01785	6.96e-76	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HBDLGIIM_01786	8.69e-230	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HBDLGIIM_01787	1.97e-46	-	-	-	-	-	-	-	-
HBDLGIIM_01788	5.09e-35	yxeD	-	-	-	-	-	-	-
HBDLGIIM_01789	2.06e-42	yxeE	-	-	-	-	-	-	-
HBDLGIIM_01792	6.65e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HBDLGIIM_01793	8.24e-220	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HBDLGIIM_01794	1.17e-144	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HBDLGIIM_01795	4.04e-265	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBDLGIIM_01796	3.85e-297	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HBDLGIIM_01797	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HBDLGIIM_01798	1.44e-226	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HBDLGIIM_01799	1.11e-299	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HBDLGIIM_01800	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HBDLGIIM_01801	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HBDLGIIM_01802	9.97e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HBDLGIIM_01803	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HBDLGIIM_01804	9.75e-85	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HBDLGIIM_01805	0.0	-	-	-	L	-	-	-	HKD family nuclease
HBDLGIIM_01806	1.26e-96	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HBDLGIIM_01807	8.44e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HBDLGIIM_01808	2.16e-230	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HBDLGIIM_01809	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HBDLGIIM_01810	5.65e-113	-	-	-	-	-	-	-	-
HBDLGIIM_01814	9.53e-93	yxxG	-	-	-	-	-	-	-
HBDLGIIM_01815	2.74e-96	yxiG	-	-	-	-	-	-	-
HBDLGIIM_01819	1.81e-11	yxiJ	-	-	S	-	-	-	YxiJ-like protein
HBDLGIIM_01821	2.96e-103	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
HBDLGIIM_01822	3.24e-77	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HBDLGIIM_01825	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HBDLGIIM_01826	4.98e-280	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HBDLGIIM_01827	3.04e-192	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HBDLGIIM_01828	1.51e-180	bglS	-	-	M	-	-	-	licheninase activity
HBDLGIIM_01829	1.91e-282	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HBDLGIIM_01830	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HBDLGIIM_01831	2.38e-65	yxiS	-	-	-	-	-	-	-
HBDLGIIM_01832	3.75e-126	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HBDLGIIM_01833	6.69e-267	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBDLGIIM_01834	4e-201	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HBDLGIIM_01835	1.33e-276	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HBDLGIIM_01836	7.13e-110	yxjI	-	-	S	-	-	-	LURP-one-related
HBDLGIIM_01839	2.22e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HBDLGIIM_01840	2.28e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBDLGIIM_01841	2.68e-120	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HBDLGIIM_01842	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBDLGIIM_01843	2.01e-212	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HBDLGIIM_01844	8.75e-260	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_01845	1.99e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HBDLGIIM_01846	4.75e-289	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HBDLGIIM_01847	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HBDLGIIM_01848	1.36e-242	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HBDLGIIM_01849	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HBDLGIIM_01850	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HBDLGIIM_01851	3.07e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBDLGIIM_01852	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HBDLGIIM_01853	3.08e-243	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HBDLGIIM_01854	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HBDLGIIM_01855	1.62e-120	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HBDLGIIM_01856	1.86e-73	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HBDLGIIM_01857	1.51e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HBDLGIIM_01858	2.97e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HBDLGIIM_01859	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HBDLGIIM_01860	2.1e-304	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBDLGIIM_01861	2.76e-64	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_01862	1.38e-65	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_01863	2.99e-289	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBDLGIIM_01864	4.51e-77	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HBDLGIIM_01865	9.23e-214	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HBDLGIIM_01866	1.38e-230	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBDLGIIM_01867	4.02e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBDLGIIM_01868	3.48e-140	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HBDLGIIM_01870	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HBDLGIIM_01871	4.46e-66	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HBDLGIIM_01872	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBDLGIIM_01873	1.18e-67	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_01874	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HBDLGIIM_01875	1.35e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HBDLGIIM_01876	1.53e-289	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HBDLGIIM_01877	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_01878	7.34e-293	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HBDLGIIM_01879	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_01880	7.08e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HBDLGIIM_01881	4.37e-214	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HBDLGIIM_01882	1.85e-151	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HBDLGIIM_01883	2.87e-248	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBDLGIIM_01884	2.5e-64	ywaE	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_01885	6.3e-209	gspA	-	-	M	-	-	-	General stress
HBDLGIIM_01886	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBDLGIIM_01887	3.28e-315	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBDLGIIM_01888	1.51e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HBDLGIIM_01889	1.64e-281	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HBDLGIIM_01890	3e-220	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HBDLGIIM_01891	5.9e-183	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HBDLGIIM_01892	9.1e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HBDLGIIM_01893	6.47e-144	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HBDLGIIM_01894	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HBDLGIIM_01895	4.83e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_01896	1.3e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HBDLGIIM_01897	1.66e-145	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HBDLGIIM_01898	9.54e-304	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HBDLGIIM_01899	1.79e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBDLGIIM_01900	4.9e-172	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
HBDLGIIM_01901	5.07e-166	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
HBDLGIIM_01903	3.72e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HBDLGIIM_01904	3.45e-81	gtcA	-	-	S	-	-	-	GtrA-like protein
HBDLGIIM_01905	2.37e-183	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HBDLGIIM_01906	8.26e-67	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HBDLGIIM_01907	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HBDLGIIM_01908	5.74e-48	ydaS	-	-	S	-	-	-	membrane
HBDLGIIM_01909	2.21e-228	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HBDLGIIM_01910	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBDLGIIM_01911	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HBDLGIIM_01912	6.76e-84	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HBDLGIIM_01913	8.51e-50	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HBDLGIIM_01914	1.35e-102	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HBDLGIIM_01915	6.27e-270	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HBDLGIIM_01916	1.14e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HBDLGIIM_01917	1.34e-235	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBDLGIIM_01918	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBDLGIIM_01920	5.46e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HBDLGIIM_01921	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_01922	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HBDLGIIM_01923	3.52e-26	ywdA	-	-	-	-	-	-	-
HBDLGIIM_01924	5.86e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HBDLGIIM_01925	3.23e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HBDLGIIM_01926	4.04e-115	ywdD	-	-	-	-	-	-	-
HBDLGIIM_01928	2.42e-194	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HBDLGIIM_01929	5.93e-170	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HBDLGIIM_01930	1.59e-57	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HBDLGIIM_01931	1.88e-291	ywdJ	-	-	F	-	-	-	Xanthine uracil
HBDLGIIM_01932	2.17e-76	ywdK	-	-	S	-	-	-	small membrane protein
HBDLGIIM_01933	6.51e-88	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HBDLGIIM_01934	9.06e-184	spsA	-	-	M	-	-	-	Spore Coat
HBDLGIIM_01935	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HBDLGIIM_01936	5.07e-282	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HBDLGIIM_01937	2.34e-206	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HBDLGIIM_01938	4.78e-272	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HBDLGIIM_01939	7.11e-172	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HBDLGIIM_01940	2.93e-235	spsG	-	-	M	-	-	-	Spore Coat
HBDLGIIM_01941	3.99e-177	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBDLGIIM_01942	4.32e-232	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HBDLGIIM_01943	3.89e-207	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HBDLGIIM_01944	1.15e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HBDLGIIM_01945	2.66e-221	bcrA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_01946	4.38e-18	-	-	-	S	-	-	-	ABC-2 family transporter protein
HBDLGIIM_01947	8.51e-123	-	-	-	S	-	-	-	ABC-2 family transporter protein
HBDLGIIM_01948	1.31e-100	-	-	-	-	-	-	-	-
HBDLGIIM_01949	1.5e-161	-	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_01950	1.29e-206	-	-	-	T	-	-	-	Histidine kinase
HBDLGIIM_01951	6.34e-314	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HBDLGIIM_01952	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HBDLGIIM_01953	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HBDLGIIM_01954	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HBDLGIIM_01955	3.45e-265	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HBDLGIIM_01956	2.25e-283	ywfA	-	-	EGP	-	-	-	-transporter
HBDLGIIM_01957	4.68e-145	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HBDLGIIM_01958	1.19e-176	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HBDLGIIM_01959	2.69e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBDLGIIM_01960	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HBDLGIIM_01961	8.14e-265	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HBDLGIIM_01962	9e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HBDLGIIM_01963	3.28e-178	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HBDLGIIM_01964	2.82e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HBDLGIIM_01965	2.03e-225	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HBDLGIIM_01966	1.19e-213	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HBDLGIIM_01967	2.25e-210	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_01968	6.17e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HBDLGIIM_01970	3.18e-236	-	-	-	-	-	-	-	-
HBDLGIIM_01973	1.03e-215	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HBDLGIIM_01974	2.24e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_01975	9.27e-121	-	-	-	S	-	-	-	membrane
HBDLGIIM_01976	7.62e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
HBDLGIIM_01977	2.48e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HBDLGIIM_01978	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HBDLGIIM_01979	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HBDLGIIM_01980	2.02e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
HBDLGIIM_01981	2.17e-313	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HBDLGIIM_01982	4.16e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_01983	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HBDLGIIM_01984	3.84e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
HBDLGIIM_01985	4.71e-124	ywhD	-	-	S	-	-	-	YwhD family
HBDLGIIM_01986	2.04e-104	-	-	-	-	-	-	-	-
HBDLGIIM_01987	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HBDLGIIM_01988	1.58e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HBDLGIIM_01989	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HBDLGIIM_01991	3.39e-96	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HBDLGIIM_01992	1.95e-56	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_01993	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HBDLGIIM_01994	2.12e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HBDLGIIM_01995	1.33e-167	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HBDLGIIM_01996	6.16e-178	ywiC	-	-	S	-	-	-	YwiC-like protein
HBDLGIIM_01997	2.79e-107	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HBDLGIIM_01998	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBDLGIIM_01999	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HBDLGIIM_02000	8.93e-124	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HBDLGIIM_02001	1.45e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HBDLGIIM_02002	1.43e-134	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBDLGIIM_02003	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBDLGIIM_02004	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HBDLGIIM_02005	1.13e-58	ywjC	-	-	-	-	-	-	-
HBDLGIIM_02006	2.32e-234	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HBDLGIIM_02007	2.97e-286	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HBDLGIIM_02008	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HBDLGIIM_02009	7.39e-74	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HBDLGIIM_02010	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HBDLGIIM_02011	3.31e-120	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HBDLGIIM_02012	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HBDLGIIM_02013	5.51e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HBDLGIIM_02014	6.37e-144	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBDLGIIM_02015	5.31e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBDLGIIM_02016	1.43e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HBDLGIIM_02017	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HBDLGIIM_02018	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HBDLGIIM_02019	5.56e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HBDLGIIM_02020	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HBDLGIIM_02021	2.02e-202	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HBDLGIIM_02022	1.72e-122	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HBDLGIIM_02023	6.14e-87	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBDLGIIM_02024	1.11e-244	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HBDLGIIM_02025	1.71e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HBDLGIIM_02027	2.08e-79	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HBDLGIIM_02028	5.18e-150	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HBDLGIIM_02029	4.23e-99	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HBDLGIIM_02030	2.53e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HBDLGIIM_02031	3.91e-118	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HBDLGIIM_02032	1.2e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBDLGIIM_02033	6.74e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HBDLGIIM_02034	3.68e-125	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HBDLGIIM_02035	2.32e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HBDLGIIM_02036	2.61e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HBDLGIIM_02037	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HBDLGIIM_02038	1.05e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HBDLGIIM_02039	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBDLGIIM_02040	1.66e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HBDLGIIM_02041	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBDLGIIM_02042	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HBDLGIIM_02043	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HBDLGIIM_02044	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HBDLGIIM_02045	3.36e-82	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HBDLGIIM_02046	1.02e-117	ywmA	-	-	-	-	-	-	-
HBDLGIIM_02047	2.25e-45	ywzB	-	-	S	-	-	-	membrane
HBDLGIIM_02048	8.35e-175	ywmB	-	-	S	-	-	-	TATA-box binding
HBDLGIIM_02049	7.05e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBDLGIIM_02050	8.17e-242	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HBDLGIIM_02051	2.59e-160	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HBDLGIIM_02052	1.5e-158	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HBDLGIIM_02054	5.24e-186	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBDLGIIM_02055	5.35e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBDLGIIM_02056	1.93e-117	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HBDLGIIM_02057	1.05e-107	ywmF	-	-	S	-	-	-	Peptidase M50
HBDLGIIM_02058	2.94e-17	csbD	-	-	K	-	-	-	CsbD-like
HBDLGIIM_02059	2.86e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HBDLGIIM_02060	1.85e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HBDLGIIM_02061	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HBDLGIIM_02062	8.87e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02063	5.3e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HBDLGIIM_02064	1.33e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HBDLGIIM_02065	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBDLGIIM_02066	1.04e-89	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HBDLGIIM_02068	1.12e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HBDLGIIM_02069	1.26e-186	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HBDLGIIM_02070	4.67e-95	ywnJ	-	-	S	-	-	-	VanZ like family
HBDLGIIM_02071	8.23e-132	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HBDLGIIM_02072	8.16e-265	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HBDLGIIM_02073	1.29e-76	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HBDLGIIM_02074	1.8e-289	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HBDLGIIM_02075	3.79e-131	yjgF	-	-	Q	-	-	-	Isochorismatase family
HBDLGIIM_02076	2.69e-310	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HBDLGIIM_02077	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HBDLGIIM_02078	4.1e-272	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_02079	3.58e-93	ywoH	-	-	K	-	-	-	transcriptional
HBDLGIIM_02080	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HBDLGIIM_02081	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HBDLGIIM_02082	1.03e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HBDLGIIM_02083	3.5e-183	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HBDLGIIM_02084	1.63e-258	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HBDLGIIM_02085	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HBDLGIIM_02086	1.87e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HBDLGIIM_02087	3.73e-90	ywpF	-	-	S	-	-	-	YwpF-like protein
HBDLGIIM_02088	4.49e-82	ywpG	-	-	-	-	-	-	-
HBDLGIIM_02089	1.47e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HBDLGIIM_02090	4.82e-181	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HBDLGIIM_02091	3.06e-201	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HBDLGIIM_02092	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HBDLGIIM_02093	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HBDLGIIM_02094	1.74e-21	-	-	-	-	-	-	-	-
HBDLGIIM_02095	3.53e-152	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HBDLGIIM_02096	6.33e-157	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HBDLGIIM_02097	8.69e-181	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HBDLGIIM_02098	5.88e-312	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HBDLGIIM_02099	1.15e-189	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HBDLGIIM_02101	2.09e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HBDLGIIM_02102	0.0	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HBDLGIIM_02103	2.05e-66	-	-	-	-	-	-	-	-
HBDLGIIM_02104	5.26e-73	-	-	-	T	-	-	-	A nuclease of the HNH/ENDO VII superfamily with conserved WHH
HBDLGIIM_02105	4.33e-43	-	-	-	M	-	-	-	COG3209 Rhs family protein
HBDLGIIM_02106	8.76e-112	-	-	-	-	-	-	-	-
HBDLGIIM_02107	1.66e-65	-	-	-	-	-	-	-	-
HBDLGIIM_02109	3.35e-62	-	-	-	-	-	-	-	-
HBDLGIIM_02110	1.99e-168	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HBDLGIIM_02111	1.39e-201	-	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02112	2.12e-120	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
HBDLGIIM_02114	1.23e-113	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HBDLGIIM_02115	6.97e-131	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HBDLGIIM_02116	1.01e-109	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HBDLGIIM_02117	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HBDLGIIM_02119	1.4e-144	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBDLGIIM_02120	1.42e-20	-	-	-	-	-	-	-	-
HBDLGIIM_02121	3.09e-268	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HBDLGIIM_02122	1.06e-184	cotB	-	-	-	ko:K06325	-	ko00000	-
HBDLGIIM_02123	3.43e-163	ywrJ	-	-	-	-	-	-	-
HBDLGIIM_02124	2.99e-306	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBDLGIIM_02125	5.35e-215	alsR	-	-	K	-	-	-	LysR substrate binding domain
HBDLGIIM_02126	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HBDLGIIM_02127	5.71e-191	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HBDLGIIM_02128	5.02e-123	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HBDLGIIM_02129	1.68e-115	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HBDLGIIM_02130	4.01e-207	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HBDLGIIM_02131	1.87e-205	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HBDLGIIM_02132	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HBDLGIIM_02133	4.8e-86	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HBDLGIIM_02134	1.39e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBDLGIIM_02135	5.21e-229	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HBDLGIIM_02136	1.69e-258	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
HBDLGIIM_02137	4.4e-247	-	-	-	E	-	-	-	Spore germination protein
HBDLGIIM_02138	6.26e-242	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HBDLGIIM_02139	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HBDLGIIM_02140	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HBDLGIIM_02141	1.39e-280	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HBDLGIIM_02142	4.04e-29	ywtC	-	-	-	-	-	-	-
HBDLGIIM_02143	2.62e-302	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HBDLGIIM_02144	9.04e-77	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HBDLGIIM_02145	1.07e-201	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HBDLGIIM_02146	1.89e-228	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02147	3.45e-315	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBDLGIIM_02148	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
HBDLGIIM_02149	1.37e-268	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HBDLGIIM_02150	2.36e-249	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HBDLGIIM_02151	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HBDLGIIM_02152	1.56e-230	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HBDLGIIM_02153	5.26e-179	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBDLGIIM_02154	1.8e-268	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HBDLGIIM_02155	4.31e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HBDLGIIM_02156	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HBDLGIIM_02157	8.85e-306	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferase 1 domain A
HBDLGIIM_02158	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HBDLGIIM_02159	2.78e-82	ymzB	-	-	-	-	-	-	-
HBDLGIIM_02160	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HBDLGIIM_02161	6.08e-06	-	-	-	-	-	-	-	-
HBDLGIIM_02162	1.61e-162	ymaC	-	-	S	-	-	-	Replication protein
HBDLGIIM_02163	1.71e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HBDLGIIM_02164	7.46e-72	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HBDLGIIM_02165	1.82e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HBDLGIIM_02167	1.4e-75	ymaF	-	-	S	-	-	-	YmaF family
HBDLGIIM_02168	3.63e-219	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HBDLGIIM_02169	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HBDLGIIM_02170	2.52e-41	-	-	-	-	-	-	-	-
HBDLGIIM_02171	9.42e-29	ymzA	-	-	-	-	-	-	-
HBDLGIIM_02172	4.63e-88	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HBDLGIIM_02173	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBDLGIIM_02174	5.77e-244	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBDLGIIM_02175	2.72e-142	ymaB	-	-	S	-	-	-	MutT family
HBDLGIIM_02176	1.07e-148	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HBDLGIIM_02177	1.55e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HBDLGIIM_02178	2.7e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBDLGIIM_02179	3.37e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HBDLGIIM_02180	4.39e-88	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HBDLGIIM_02181	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HBDLGIIM_02185	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HBDLGIIM_02186	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HBDLGIIM_02187	4.12e-274	xylR	-	-	GK	-	-	-	ROK family
HBDLGIIM_02188	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HBDLGIIM_02190	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HBDLGIIM_02191	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HBDLGIIM_02195	1.28e-26	-	-	-	-	-	-	-	-
HBDLGIIM_02196	5.89e-151	yobV	-	-	K	-	-	-	WYL domain
HBDLGIIM_02197	1.93e-86	dinB	-	-	S	-	-	-	DinB family
HBDLGIIM_02198	2.07e-237	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HBDLGIIM_02199	4.66e-20	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HBDLGIIM_02201	6.73e-23	-	-	-	-	-	-	-	-
HBDLGIIM_02202	1.39e-05	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HBDLGIIM_02203	2.22e-182	yoaP	-	-	K	-	-	-	YoaP-like
HBDLGIIM_02204	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HBDLGIIM_02205	6.87e-277	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HBDLGIIM_02206	5.6e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_02207	1.49e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HBDLGIIM_02208	3.66e-182	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HBDLGIIM_02209	4.43e-120	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBDLGIIM_02210	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBDLGIIM_02211	9.23e-249	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HBDLGIIM_02212	2.41e-301	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HBDLGIIM_02213	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HBDLGIIM_02215	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HBDLGIIM_02216	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HBDLGIIM_02217	8.28e-101	yclD	-	-	-	-	-	-	-
HBDLGIIM_02218	2.83e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
HBDLGIIM_02219	5.03e-311	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HBDLGIIM_02220	1.51e-26	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HBDLGIIM_02221	3.44e-130	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HBDLGIIM_02222	3.45e-205	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HBDLGIIM_02223	1.89e-185	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HBDLGIIM_02224	3.03e-154	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HBDLGIIM_02225	1.13e-168	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HBDLGIIM_02226	8.56e-142	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HBDLGIIM_02227	4.34e-166	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HBDLGIIM_02228	2.86e-316	-	-	-	E	-	-	-	Aminotransferase class I and II
HBDLGIIM_02229	2.06e-178	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HBDLGIIM_02230	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HBDLGIIM_02231	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_02232	7.73e-277	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBDLGIIM_02233	9.84e-192	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HBDLGIIM_02234	6.89e-195	yycI	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_02235	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_02236	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_02237	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_02242	8.99e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBDLGIIM_02243	1.29e-93	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBDLGIIM_02244	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HBDLGIIM_02245	1.09e-38	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HBDLGIIM_02247	3.6e-25	yycC	-	-	K	-	-	-	YycC-like protein
HBDLGIIM_02248	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HBDLGIIM_02249	2.85e-302	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HBDLGIIM_02250	3.03e-257	-	-	-	S	-	-	-	Ecdysteroid kinase
HBDLGIIM_02251	1.14e-297	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
HBDLGIIM_02252	9.47e-299	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HBDLGIIM_02253	1.46e-155	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HBDLGIIM_02254	9.66e-114	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
HBDLGIIM_02255	1.58e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HBDLGIIM_02256	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HBDLGIIM_02257	1.37e-201	yybS	-	-	S	-	-	-	membrane
HBDLGIIM_02259	3.33e-111	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HBDLGIIM_02260	4.56e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02261	2.95e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HBDLGIIM_02262	3.12e-65	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HBDLGIIM_02263	1.85e-32	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HBDLGIIM_02264	3.72e-217	yvlB	-	-	S	-	-	-	Putative adhesin
HBDLGIIM_02265	4.87e-66	yvlA	-	-	-	-	-	-	-
HBDLGIIM_02266	8.07e-44	yvkN	-	-	-	-	-	-	-
HBDLGIIM_02267	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HBDLGIIM_02268	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HBDLGIIM_02269	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_02270	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HBDLGIIM_02271	1.35e-143	yvkB	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02272	6.9e-297	yvkA	-	-	P	-	-	-	-transporter
HBDLGIIM_02273	4.57e-62	-	-	-	Q	-	-	-	Thioesterase domain
HBDLGIIM_02274	5.04e-232	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HBDLGIIM_02275	3.33e-59	-	-	-	E	-	-	-	Saccharopine dehydrogenase
HBDLGIIM_02276	2.64e-117	-	-	-	V	-	-	-	ABC transporter transmembrane region
HBDLGIIM_02277	4.29e-125	nrpS2	-	-	Q	-	-	-	Non-ribosomal peptide synthetase modules and related proteins
HBDLGIIM_02278	3.88e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HBDLGIIM_02279	1.9e-187	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HBDLGIIM_02280	1.02e-210	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Isocitrate/isopropylmalate dehydrogenase
HBDLGIIM_02281	2.29e-154	ydhC	-	-	K	-	-	-	FCD
HBDLGIIM_02282	2.76e-290	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HBDLGIIM_02285	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
HBDLGIIM_02287	2.49e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HBDLGIIM_02288	1.58e-247	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HBDLGIIM_02289	2.4e-170	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HBDLGIIM_02290	3.25e-154	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HBDLGIIM_02291	1.23e-276	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HBDLGIIM_02292	1.48e-65	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HBDLGIIM_02293	4.48e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HBDLGIIM_02294	3.63e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02295	0.0	ybeC	-	-	E	-	-	-	amino acid
HBDLGIIM_02296	4.41e-214	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HBDLGIIM_02297	2.06e-112	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HBDLGIIM_02298	6.66e-236	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HBDLGIIM_02299	0.0	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBDLGIIM_02302	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HBDLGIIM_02303	0.0	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HBDLGIIM_02304	1.29e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HBDLGIIM_02305	5.78e-139	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HBDLGIIM_02306	1.59e-285	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HBDLGIIM_02307	5.67e-259	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HBDLGIIM_02309	3.57e-157	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HBDLGIIM_02310	6.7e-148	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HBDLGIIM_02311	7.12e-278	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HBDLGIIM_02312	1.44e-128	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HBDLGIIM_02313	2.04e-110	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HBDLGIIM_02314	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBDLGIIM_02315	6.9e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HBDLGIIM_02316	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HBDLGIIM_02317	5.4e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HBDLGIIM_02318	1.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HBDLGIIM_02320	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_02321	0.0	-	-	-	Q	ko:K15654	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Non-ribosomal peptide synthetase modules and related proteins
HBDLGIIM_02322	3.29e-120	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBDLGIIM_02323	1.06e-145	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HBDLGIIM_02324	1.91e-125	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HBDLGIIM_02326	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HBDLGIIM_02327	9.88e-100	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HBDLGIIM_02328	3.91e-154	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HBDLGIIM_02329	1.55e-151	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HBDLGIIM_02330	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HBDLGIIM_02331	1.06e-278	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HBDLGIIM_02332	2.74e-206	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBDLGIIM_02333	3.36e-270	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HBDLGIIM_02334	1.71e-262	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HBDLGIIM_02335	4.41e-247	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HBDLGIIM_02336	6.38e-258	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HBDLGIIM_02337	1.05e-249	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HBDLGIIM_02338	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBDLGIIM_02339	1.3e-138	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HBDLGIIM_02340	4.67e-78	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HBDLGIIM_02341	2.72e-282	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HBDLGIIM_02342	1.51e-235	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HBDLGIIM_02343	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
HBDLGIIM_02344	1.27e-306	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HBDLGIIM_02345	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HBDLGIIM_02346	1.26e-155	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HBDLGIIM_02347	5.07e-281	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBDLGIIM_02348	3.55e-172	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HBDLGIIM_02349	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HBDLGIIM_02350	1.44e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HBDLGIIM_02351	3.22e-289	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HBDLGIIM_02352	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HBDLGIIM_02353	1.28e-193	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
HBDLGIIM_02355	4.71e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HBDLGIIM_02356	3.02e-202	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HBDLGIIM_02357	8.74e-160	yvbU	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02358	7.57e-243	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBDLGIIM_02359	7.79e-261	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HBDLGIIM_02360	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBDLGIIM_02362	2.95e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HBDLGIIM_02363	8.12e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HBDLGIIM_02364	1.09e-274	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HBDLGIIM_02365	4.28e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HBDLGIIM_02366	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HBDLGIIM_02367	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HBDLGIIM_02368	1.38e-91	yvbK	-	-	K	-	-	-	acetyltransferase
HBDLGIIM_02369	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HBDLGIIM_02370	3.62e-155	yvbI	-	-	M	-	-	-	Membrane
HBDLGIIM_02371	6.3e-134	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HBDLGIIM_02372	3.38e-128	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HBDLGIIM_02373	5.16e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HBDLGIIM_02374	1.61e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HBDLGIIM_02375	3.79e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HBDLGIIM_02376	6.21e-141	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HBDLGIIM_02377	3.42e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HBDLGIIM_02378	4.07e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HBDLGIIM_02379	3.4e-146	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HBDLGIIM_02380	4.61e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HBDLGIIM_02381	6e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HBDLGIIM_02382	1.27e-160	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_02383	3.31e-155	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HBDLGIIM_02384	9.99e-170	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HBDLGIIM_02385	1.76e-154	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HBDLGIIM_02386	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HBDLGIIM_02387	2.97e-70	yvaP	-	-	K	-	-	-	transcriptional
HBDLGIIM_02388	3.52e-96	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HBDLGIIM_02389	1.11e-91	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HBDLGIIM_02390	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
HBDLGIIM_02391	4.58e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HBDLGIIM_02392	5.69e-182	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HBDLGIIM_02393	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HBDLGIIM_02394	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HBDLGIIM_02396	5.05e-58	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HBDLGIIM_02397	1.6e-179	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBDLGIIM_02398	6.6e-205	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HBDLGIIM_02399	3.16e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HBDLGIIM_02400	1.76e-169	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HBDLGIIM_02401	9.06e-191	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HBDLGIIM_02402	1.04e-156	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBDLGIIM_02403	5.56e-154	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBDLGIIM_02404	1.49e-179	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HBDLGIIM_02405	3.7e-234	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBDLGIIM_02406	1.44e-61	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
HBDLGIIM_02407	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBDLGIIM_02408	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBDLGIIM_02409	1.22e-249	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HBDLGIIM_02410	8.06e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HBDLGIIM_02411	3.24e-40	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
HBDLGIIM_02412	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HBDLGIIM_02413	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HBDLGIIM_02414	3.33e-140	bdbD	-	-	O	-	-	-	Thioredoxin
HBDLGIIM_02415	2.93e-93	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HBDLGIIM_02416	3.84e-190	-	-	-	S	-	-	-	Metallo-peptidase family M12
HBDLGIIM_02417	6.36e-130	yvgT	-	-	S	-	-	-	membrane
HBDLGIIM_02418	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBDLGIIM_02419	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HBDLGIIM_02420	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HBDLGIIM_02421	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HBDLGIIM_02422	3.25e-112	yvgO	-	-	-	-	-	-	-
HBDLGIIM_02423	1.03e-199	yvgN	-	-	S	-	-	-	reductase
HBDLGIIM_02424	3.58e-262	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HBDLGIIM_02425	2.46e-249	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HBDLGIIM_02426	4.76e-218	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HBDLGIIM_02427	1.43e-251	-	-	-	T	-	-	-	Histidine kinase
HBDLGIIM_02428	8.36e-146	yfiK	-	-	K	-	-	-	Regulator
HBDLGIIM_02429	5.72e-127	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HBDLGIIM_02430	4.78e-179	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HBDLGIIM_02431	5.75e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HBDLGIIM_02432	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HBDLGIIM_02433	1.01e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HBDLGIIM_02434	3.7e-20	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HBDLGIIM_02435	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HBDLGIIM_02436	5.89e-158	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HBDLGIIM_02437	5.22e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HBDLGIIM_02438	1.9e-237	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBDLGIIM_02439	9.64e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBDLGIIM_02440	9.78e-189	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HBDLGIIM_02441	8.03e-87	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HBDLGIIM_02442	3.11e-295	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HBDLGIIM_02443	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
HBDLGIIM_02444	3.23e-134	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HBDLGIIM_02445	9.71e-50	-	-	-	-	-	-	-	-
HBDLGIIM_02446	2.7e-172	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_02447	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HBDLGIIM_02448	7.64e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HBDLGIIM_02449	7.09e-180	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBDLGIIM_02450	1.16e-215	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HBDLGIIM_02451	2.04e-228	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBDLGIIM_02452	3.47e-285	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HBDLGIIM_02453	8.89e-131	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HBDLGIIM_02454	1.37e-289	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_02455	1.62e-68	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HBDLGIIM_02456	9.74e-134	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HBDLGIIM_02457	2.76e-190	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HBDLGIIM_02458	8.92e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HBDLGIIM_02459	4.06e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_02460	8.35e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBDLGIIM_02461	2.16e-262	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HBDLGIIM_02462	5.31e-245	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HBDLGIIM_02463	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HBDLGIIM_02464	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HBDLGIIM_02465	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HBDLGIIM_02466	3.99e-200	yuxN	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02467	2.68e-32	-	-	-	-	-	-	-	-
HBDLGIIM_02468	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_02469	3.7e-163	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_02470	1.47e-302	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBDLGIIM_02471	4.12e-103	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HBDLGIIM_02472	5.03e-193	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBDLGIIM_02473	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HBDLGIIM_02474	7.61e-60	-	-	-	S	-	-	-	YusW-like protein
HBDLGIIM_02475	9.06e-193	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HBDLGIIM_02476	2.15e-52	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HBDLGIIM_02477	5.96e-241	apbA	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBDLGIIM_02478	1.38e-174	-	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HBDLGIIM_02479	1.39e-202	-	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02480	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HBDLGIIM_02481	9.65e-92	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HBDLGIIM_02482	2.58e-71	yusN	-	-	M	-	-	-	Coat F domain
HBDLGIIM_02483	3.2e-58	-	-	-	-	-	-	-	-
HBDLGIIM_02484	5.35e-215	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HBDLGIIM_02485	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HBDLGIIM_02486	7.74e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HBDLGIIM_02487	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HBDLGIIM_02488	7.13e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HBDLGIIM_02489	4.16e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HBDLGIIM_02490	3.1e-55	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HBDLGIIM_02491	3.6e-81	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HBDLGIIM_02492	1.64e-72	yusE	-	-	CO	-	-	-	Thioredoxin
HBDLGIIM_02493	1.29e-76	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HBDLGIIM_02494	3.71e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBDLGIIM_02495	1.46e-138	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HBDLGIIM_02496	1.49e-185	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HBDLGIIM_02497	8.85e-85	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBDLGIIM_02498	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HBDLGIIM_02499	5.01e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HBDLGIIM_02500	6.62e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBDLGIIM_02501	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HBDLGIIM_02502	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HBDLGIIM_02503	3.07e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HBDLGIIM_02504	5.14e-95	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HBDLGIIM_02505	1.36e-159	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HBDLGIIM_02506	7.79e-261	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HBDLGIIM_02507	5.74e-86	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HBDLGIIM_02509	4.94e-28	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HBDLGIIM_02510	5.4e-95	-	-	-	-	-	-	-	-
HBDLGIIM_02512	1.51e-208	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HBDLGIIM_02513	2.61e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HBDLGIIM_02514	6.08e-312	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HBDLGIIM_02515	4.32e-202	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBDLGIIM_02516	3.6e-209	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HBDLGIIM_02517	1.52e-205	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HBDLGIIM_02518	3.98e-171	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HBDLGIIM_02519	1.3e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_02520	7.06e-218	bsn	-	-	L	-	-	-	Ribonuclease
HBDLGIIM_02521	2.58e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HBDLGIIM_02522	2.42e-301	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HBDLGIIM_02523	1.05e-274	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_02524	1.02e-86	-	-	-	-	-	-	-	-
HBDLGIIM_02525	1.18e-225	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
HBDLGIIM_02527	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HBDLGIIM_02528	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HBDLGIIM_02529	5.25e-81	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
HBDLGIIM_02530	1.8e-217	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HBDLGIIM_02531	1.01e-184	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HBDLGIIM_02532	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HBDLGIIM_02533	1.31e-165	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HBDLGIIM_02534	8.24e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HBDLGIIM_02535	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBDLGIIM_02536	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_02537	2.2e-95	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HBDLGIIM_02538	4.82e-179	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HBDLGIIM_02539	1.5e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HBDLGIIM_02540	1.55e-250	yutH	-	-	S	-	-	-	Spore coat protein
HBDLGIIM_02541	8.26e-308	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HBDLGIIM_02542	9.35e-251	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HBDLGIIM_02543	2.26e-215	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HBDLGIIM_02544	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HBDLGIIM_02545	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HBDLGIIM_02546	1.34e-72	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_02547	1.71e-265	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HBDLGIIM_02548	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HBDLGIIM_02549	1.74e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBDLGIIM_02550	9.18e-207	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HBDLGIIM_02551	1.38e-82	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HBDLGIIM_02552	1.28e-177	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBDLGIIM_02553	3.25e-20	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HBDLGIIM_02554	3.21e-94	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HBDLGIIM_02556	5.3e-44	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
HBDLGIIM_02558	2.66e-156	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HBDLGIIM_02559	3.42e-92	-	-	-	CP	-	-	-	Membrane
HBDLGIIM_02560	5.68e-40	-	-	-	-	-	-	-	-
HBDLGIIM_02561	3.86e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HBDLGIIM_02563	4.19e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HBDLGIIM_02564	1.7e-300	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HBDLGIIM_02565	8.54e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
HBDLGIIM_02566	2.83e-152	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_02567	4.99e-101	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HBDLGIIM_02568	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HBDLGIIM_02569	8.19e-276	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HBDLGIIM_02570	3.73e-131	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HBDLGIIM_02571	1.13e-155	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HBDLGIIM_02572	3.61e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HBDLGIIM_02573	6.07e-172	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBDLGIIM_02574	1.52e-283	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HBDLGIIM_02575	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HBDLGIIM_02576	4.79e-221	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HBDLGIIM_02577	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_02578	1.91e-46	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HBDLGIIM_02579	3.06e-171	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HBDLGIIM_02580	5.7e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HBDLGIIM_02581	1.49e-291	yukF	-	-	QT	-	-	-	Transcriptional regulator
HBDLGIIM_02582	2.36e-61	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HBDLGIIM_02583	5.28e-53	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HBDLGIIM_02584	1.38e-276	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HBDLGIIM_02585	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HBDLGIIM_02586	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HBDLGIIM_02587	1.55e-99	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HBDLGIIM_02588	4.12e-169	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBDLGIIM_02589	2.23e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HBDLGIIM_02590	2.46e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HBDLGIIM_02591	2.67e-238	yueF	-	-	S	-	-	-	transporter activity
HBDLGIIM_02592	6.33e-46	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HBDLGIIM_02593	2.23e-50	yueH	-	-	S	-	-	-	YueH-like protein
HBDLGIIM_02594	7.94e-90	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HBDLGIIM_02595	8.02e-135	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HBDLGIIM_02596	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HBDLGIIM_02597	3.97e-295	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HBDLGIIM_02598	2.18e-69	yuzC	-	-	-	-	-	-	-
HBDLGIIM_02599	2.66e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
HBDLGIIM_02600	2.2e-118	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Polyprenyl synthetase
HBDLGIIM_02601	2.03e-97	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_02602	1.07e-270	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_02603	1.9e-146	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBDLGIIM_02604	3.42e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HBDLGIIM_02605	1.71e-78	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HBDLGIIM_02606	5.47e-52	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBDLGIIM_02607	5.83e-100	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBDLGIIM_02608	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBDLGIIM_02609	1.47e-67	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBDLGIIM_02610	6.3e-90	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HBDLGIIM_02611	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HBDLGIIM_02613	1.79e-217	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HBDLGIIM_02614	2.72e-238	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HBDLGIIM_02615	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_02616	4.98e-250	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HBDLGIIM_02617	5.63e-163	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HBDLGIIM_02618	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HBDLGIIM_02619	1.6e-101	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HBDLGIIM_02620	1.07e-94	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_02621	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HBDLGIIM_02622	3.19e-264	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HBDLGIIM_02623	3.22e-152	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HBDLGIIM_02624	5.66e-88	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HBDLGIIM_02625	7.38e-292	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_02626	1.35e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HBDLGIIM_02627	1e-53	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HBDLGIIM_02628	5.72e-200	yugF	-	-	I	-	-	-	Hydrolase
HBDLGIIM_02629	3.75e-109	alaR	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02630	1.68e-266	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HBDLGIIM_02631	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HBDLGIIM_02632	3.14e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HBDLGIIM_02633	6.7e-286	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HBDLGIIM_02634	1.37e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HBDLGIIM_02635	5.07e-151	ycaC	-	-	Q	-	-	-	Isochorismatase family
HBDLGIIM_02636	9.29e-132	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HBDLGIIM_02637	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HBDLGIIM_02639	8.53e-95	yugN	-	-	S	-	-	-	YugN-like family
HBDLGIIM_02640	4.84e-231	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HBDLGIIM_02641	8.53e-36	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HBDLGIIM_02642	2.51e-22	-	-	-	-	-	-	-	-
HBDLGIIM_02643	1.67e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HBDLGIIM_02644	1.63e-296	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HBDLGIIM_02645	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HBDLGIIM_02646	1.76e-99	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HBDLGIIM_02647	1.72e-243	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HBDLGIIM_02648	9.33e-24	-	-	-	-	-	-	-	-
HBDLGIIM_02649	2.22e-179	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HBDLGIIM_02650	1.89e-315	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBDLGIIM_02651	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBDLGIIM_02652	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBDLGIIM_02653	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBDLGIIM_02654	1.64e-125	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HBDLGIIM_02655	1.35e-237	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HBDLGIIM_02656	2.34e-249	yubA	-	-	S	-	-	-	transporter activity
HBDLGIIM_02657	6.56e-187	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HBDLGIIM_02659	1.11e-70	yjcN	-	-	-	-	-	-	-
HBDLGIIM_02660	4.53e-158	-	-	-	G	-	-	-	Cupin
HBDLGIIM_02661	2.16e-284	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBDLGIIM_02662	4.65e-194	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBDLGIIM_02663	3.04e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HBDLGIIM_02664	1.87e-120	yuaB	-	-	-	-	-	-	-
HBDLGIIM_02665	9.66e-123	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HBDLGIIM_02666	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HBDLGIIM_02667	4.99e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HBDLGIIM_02668	1.95e-140	-	-	-	S	-	-	-	MOSC domain
HBDLGIIM_02669	3.11e-106	yuaE	-	-	S	-	-	-	DinB superfamily
HBDLGIIM_02670	6.54e-108	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HBDLGIIM_02671	2.06e-275	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HBDLGIIM_02672	2.33e-123	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HBDLGIIM_02673	3.6e-226	-	-	-	L	-	-	-	Replication protein
HBDLGIIM_02675	7.23e-99	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
HBDLGIIM_02676	5.09e-304	pre	-	-	D	-	-	-	plasmid recombination enzyme
HBDLGIIM_02677	1.81e-108	-	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_02679	2.12e-97	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBDLGIIM_02680	2.43e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HBDLGIIM_02681	1.23e-164	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HBDLGIIM_02682	4.21e-266	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HBDLGIIM_02683	6.52e-270	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HBDLGIIM_02685	7.04e-07	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HBDLGIIM_02686	1.05e-75	-	-	-	-	-	-	-	-
HBDLGIIM_02687	1.47e-91	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HBDLGIIM_02688	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HBDLGIIM_02714	4.27e-151	yoaK	-	-	S	-	-	-	Membrane
HBDLGIIM_02715	3.51e-101	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HBDLGIIM_02716	2.19e-26	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HBDLGIIM_02717	2.7e-252	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HBDLGIIM_02718	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
HBDLGIIM_02719	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HBDLGIIM_02720	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_02721	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_02722	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HBDLGIIM_02723	3.99e-179	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HBDLGIIM_02724	1.76e-186	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
HBDLGIIM_02725	1.73e-307	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HBDLGIIM_02726	2.51e-47	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
HBDLGIIM_02727	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HBDLGIIM_02728	4.5e-234	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
HBDLGIIM_02729	3.33e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HBDLGIIM_02730	1.65e-165	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
HBDLGIIM_02736	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBDLGIIM_02737	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HBDLGIIM_02738	7.09e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HBDLGIIM_02739	2.11e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HBDLGIIM_02740	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HBDLGIIM_02741	1.75e-274	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HBDLGIIM_02742	6.53e-248	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HBDLGIIM_02743	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HBDLGIIM_02744	3.72e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HBDLGIIM_02745	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HBDLGIIM_02746	3.53e-275	pbpX	-	-	V	-	-	-	Beta-lactamase
HBDLGIIM_02747	3.06e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HBDLGIIM_02748	2.2e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HBDLGIIM_02749	1.17e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBDLGIIM_02750	5.76e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HBDLGIIM_02751	3.14e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HBDLGIIM_02752	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HBDLGIIM_02753	8.26e-164	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HBDLGIIM_02754	5.59e-308	ymfH	-	-	S	-	-	-	zinc protease
HBDLGIIM_02755	1.12e-306	albE	-	-	S	-	-	-	Peptidase M16
HBDLGIIM_02756	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HBDLGIIM_02757	9.88e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_02758	9.04e-296	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_02759	4.48e-172	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_02760	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HBDLGIIM_02761	6.32e-42	-	-	-	S	-	-	-	YlzJ-like protein
HBDLGIIM_02762	2.27e-166	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HBDLGIIM_02763	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBDLGIIM_02764	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBDLGIIM_02765	2e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HBDLGIIM_02766	9.62e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBDLGIIM_02767	1.93e-137	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HBDLGIIM_02768	3.31e-206	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HBDLGIIM_02769	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HBDLGIIM_02770	1.45e-299	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HBDLGIIM_02771	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HBDLGIIM_02772	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HBDLGIIM_02773	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HBDLGIIM_02774	4.31e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HBDLGIIM_02775	1.48e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBDLGIIM_02776	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HBDLGIIM_02777	3.88e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HBDLGIIM_02778	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HBDLGIIM_02779	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HBDLGIIM_02780	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HBDLGIIM_02781	1.16e-263	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HBDLGIIM_02782	3.28e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HBDLGIIM_02783	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBDLGIIM_02784	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HBDLGIIM_02785	1.28e-293	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HBDLGIIM_02786	2.2e-273	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HBDLGIIM_02787	3.8e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HBDLGIIM_02788	1.57e-186	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBDLGIIM_02789	1.94e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HBDLGIIM_02790	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HBDLGIIM_02791	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HBDLGIIM_02792	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HBDLGIIM_02793	1.68e-93	ylxL	-	-	-	-	-	-	-
HBDLGIIM_02794	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBDLGIIM_02795	2.86e-113	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HBDLGIIM_02796	5.91e-143	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HBDLGIIM_02797	2.49e-105	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HBDLGIIM_02798	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HBDLGIIM_02799	4.97e-249	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HBDLGIIM_02800	7.41e-199	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HBDLGIIM_02801	6.52e-249	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HBDLGIIM_02802	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HBDLGIIM_02803	1.03e-241	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HBDLGIIM_02804	6.69e-167	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HBDLGIIM_02805	3.15e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HBDLGIIM_02806	6.02e-142	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HBDLGIIM_02807	2.68e-143	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HBDLGIIM_02808	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HBDLGIIM_02809	8.13e-246	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBDLGIIM_02810	5.43e-230	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HBDLGIIM_02811	1.49e-77	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HBDLGIIM_02812	2.79e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HBDLGIIM_02813	5.15e-95	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HBDLGIIM_02814	6.35e-262	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HBDLGIIM_02815	1.98e-88	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HBDLGIIM_02816	2.17e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HBDLGIIM_02817	4.26e-308	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HBDLGIIM_02818	5.62e-122	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HBDLGIIM_02819	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HBDLGIIM_02820	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HBDLGIIM_02821	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HBDLGIIM_02822	2.63e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HBDLGIIM_02823	2.8e-84	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HBDLGIIM_02824	2.77e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HBDLGIIM_02825	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HBDLGIIM_02826	6.07e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HBDLGIIM_02827	6.29e-220	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HBDLGIIM_02828	3.83e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HBDLGIIM_02829	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBDLGIIM_02830	2.55e-216	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HBDLGIIM_02831	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HBDLGIIM_02832	2.02e-270	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HBDLGIIM_02833	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HBDLGIIM_02834	0.0	ylqG	-	-	-	-	-	-	-
HBDLGIIM_02835	8.29e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBDLGIIM_02836	5.09e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HBDLGIIM_02837	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HBDLGIIM_02838	1.98e-176	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HBDLGIIM_02839	1.51e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBDLGIIM_02840	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
HBDLGIIM_02841	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HBDLGIIM_02842	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HBDLGIIM_02843	1.47e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBDLGIIM_02844	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HBDLGIIM_02845	4.31e-182	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HBDLGIIM_02846	1.87e-224	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HBDLGIIM_02847	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HBDLGIIM_02848	1.23e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HBDLGIIM_02849	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBDLGIIM_02850	8.61e-168	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HBDLGIIM_02851	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HBDLGIIM_02852	3.14e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HBDLGIIM_02853	4.38e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HBDLGIIM_02854	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBDLGIIM_02855	2.4e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HBDLGIIM_02856	4.15e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HBDLGIIM_02857	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HBDLGIIM_02858	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_02859	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HBDLGIIM_02860	4.52e-154	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HBDLGIIM_02861	4.66e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HBDLGIIM_02862	7.27e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HBDLGIIM_02863	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HBDLGIIM_02864	1.43e-177	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HBDLGIIM_02865	8.79e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HBDLGIIM_02866	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HBDLGIIM_02867	1.59e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HBDLGIIM_02868	2.04e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HBDLGIIM_02869	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBDLGIIM_02870	2.18e-287	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBDLGIIM_02871	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HBDLGIIM_02872	4.91e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HBDLGIIM_02873	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HBDLGIIM_02874	2.14e-198	yloC	-	-	S	-	-	-	stress-induced protein
HBDLGIIM_02875	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HBDLGIIM_02876	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HBDLGIIM_02877	2.98e-104	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HBDLGIIM_02878	2.92e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HBDLGIIM_02879	3.41e-184	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HBDLGIIM_02880	6.76e-143	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HBDLGIIM_02881	5.29e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HBDLGIIM_02882	3.47e-228	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HBDLGIIM_02883	9.88e-181	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HBDLGIIM_02885	6.31e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HBDLGIIM_02886	2.12e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HBDLGIIM_02887	1.05e-221	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HBDLGIIM_02888	3.54e-181	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HBDLGIIM_02889	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HBDLGIIM_02890	3.09e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HBDLGIIM_02891	4.47e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HBDLGIIM_02892	1.26e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HBDLGIIM_02893	3.28e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HBDLGIIM_02894	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HBDLGIIM_02895	3.61e-214	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HBDLGIIM_02896	1.02e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HBDLGIIM_02897	4.06e-81	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HBDLGIIM_02898	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBDLGIIM_02899	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HBDLGIIM_02900	6.12e-182	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HBDLGIIM_02901	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HBDLGIIM_02902	7.98e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HBDLGIIM_02903	1.44e-158	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HBDLGIIM_02904	9.55e-206	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HBDLGIIM_02905	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
HBDLGIIM_02906	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HBDLGIIM_02907	1.97e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HBDLGIIM_02908	9.33e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBDLGIIM_02909	7.35e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBDLGIIM_02910	3.91e-216	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HBDLGIIM_02911	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HBDLGIIM_02912	4.32e-259	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBDLGIIM_02913	1.57e-298	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HBDLGIIM_02914	1.88e-179	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HBDLGIIM_02915	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HBDLGIIM_02916	7.74e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HBDLGIIM_02917	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HBDLGIIM_02918	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HBDLGIIM_02919	7.04e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBDLGIIM_02920	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBDLGIIM_02921	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HBDLGIIM_02922	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HBDLGIIM_02923	1.98e-67	ftsL	-	-	D	-	-	-	Essential cell division protein
HBDLGIIM_02924	4.08e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HBDLGIIM_02925	3.7e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HBDLGIIM_02926	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HBDLGIIM_02927	2.68e-207	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBDLGIIM_02928	1.14e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
HBDLGIIM_02929	8.95e-111	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HBDLGIIM_02930	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HBDLGIIM_02931	4.88e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HBDLGIIM_02932	2.48e-293	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HBDLGIIM_02933	4.36e-240	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HBDLGIIM_02934	2.48e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HBDLGIIM_02935	5.88e-277	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HBDLGIIM_02936	8.3e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HBDLGIIM_02937	7.68e-116	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HBDLGIIM_02939	3.94e-57	ylbG	-	-	S	-	-	-	UPF0298 protein
HBDLGIIM_02940	3.33e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HBDLGIIM_02941	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HBDLGIIM_02942	8.47e-87	ylbD	-	-	S	-	-	-	Putative coat protein
HBDLGIIM_02943	1.62e-254	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HBDLGIIM_02944	9.59e-96	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HBDLGIIM_02945	1.68e-78	ylbA	-	-	S	-	-	-	YugN-like family
HBDLGIIM_02960	4.55e-260	-	-	-	C	-	-	-	Na+/H+ antiporter family
HBDLGIIM_02961	4.86e-41	-	-	-	C	-	-	-	Na+/H+ antiporter family
HBDLGIIM_02962	4.02e-171	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HBDLGIIM_02963	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HBDLGIIM_02964	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
HBDLGIIM_02966	2.71e-292	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
HBDLGIIM_02967	8.22e-179	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HBDLGIIM_02968	8.39e-160	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBDLGIIM_02969	4.46e-169	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_02970	1.63e-168	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_02971	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HBDLGIIM_02972	2.71e-233	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HBDLGIIM_02973	4.5e-180	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HBDLGIIM_02974	1.06e-230	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HBDLGIIM_02975	8.27e-186	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HBDLGIIM_02976	1.74e-272	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HBDLGIIM_02977	1.18e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HBDLGIIM_02978	3.16e-107	ygaO	-	-	-	-	-	-	-
HBDLGIIM_02980	9.43e-139	yhzB	-	-	S	-	-	-	B3/4 domain
HBDLGIIM_02981	2.08e-287	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBDLGIIM_02982	2.13e-226	yhbB	-	-	S	-	-	-	Putative amidase domain
HBDLGIIM_02983	4.84e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HBDLGIIM_02984	1.39e-140	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HBDLGIIM_02985	1.98e-85	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HBDLGIIM_02986	1.1e-91	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HBDLGIIM_02987	1.23e-07	-	-	-	-	-	-	-	-
HBDLGIIM_02988	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HBDLGIIM_02989	5.45e-279	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HBDLGIIM_02990	4.15e-98	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HBDLGIIM_02991	1.54e-132	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HBDLGIIM_02992	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HBDLGIIM_02993	9.09e-129	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HBDLGIIM_02994	4.73e-71	yhcC	-	-	-	-	-	-	-
HBDLGIIM_02995	5.8e-67	-	-	-	-	-	-	-	-
HBDLGIIM_02996	2.33e-81	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_02997	1.78e-162	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_02998	2.35e-215	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_02999	9.06e-209	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HBDLGIIM_03000	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HBDLGIIM_03001	1.68e-189	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HBDLGIIM_03002	1.78e-234	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HBDLGIIM_03003	6.4e-294	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBDLGIIM_03004	1.3e-63	yhcM	-	-	-	-	-	-	-
HBDLGIIM_03005	1.18e-114	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HBDLGIIM_03006	1.49e-194	yhcP	-	-	-	-	-	-	-
HBDLGIIM_03007	4.41e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
HBDLGIIM_03008	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HBDLGIIM_03009	2.5e-125	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HBDLGIIM_03010	3.87e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HBDLGIIM_03011	4.99e-88	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HBDLGIIM_03012	6.12e-91	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HBDLGIIM_03013	1.97e-160	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HBDLGIIM_03014	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HBDLGIIM_03015	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBDLGIIM_03016	1.66e-131	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HBDLGIIM_03017	1.83e-195	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HBDLGIIM_03018	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBDLGIIM_03019	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HBDLGIIM_03020	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HBDLGIIM_03021	5.28e-263	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_03022	3.15e-143	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBDLGIIM_03023	2.3e-114	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HBDLGIIM_03024	6.98e-53	yhdB	-	-	S	-	-	-	YhdB-like protein
HBDLGIIM_03025	2.42e-70	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HBDLGIIM_03026	1.41e-295	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HBDLGIIM_03027	1.32e-96	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HBDLGIIM_03028	0.0	ygxB	-	-	M	-	-	-	Conserved TM helix
HBDLGIIM_03029	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HBDLGIIM_03030	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HBDLGIIM_03031	5.07e-174	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HBDLGIIM_03032	7e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_03033	3.86e-260	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HBDLGIIM_03034	1.58e-205	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBDLGIIM_03035	1.78e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HBDLGIIM_03036	7.22e-268	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HBDLGIIM_03037	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HBDLGIIM_03038	6.88e-257	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HBDLGIIM_03039	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBDLGIIM_03040	1.59e-142	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HBDLGIIM_03041	4.59e-306	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HBDLGIIM_03042	1.19e-93	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HBDLGIIM_03043	1.92e-284	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HBDLGIIM_03044	2.24e-300	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HBDLGIIM_03045	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HBDLGIIM_03046	2.12e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBDLGIIM_03047	1.38e-85	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBDLGIIM_03048	2.12e-164	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HBDLGIIM_03049	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HBDLGIIM_03050	6.68e-262	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HBDLGIIM_03051	1.9e-176	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HBDLGIIM_03052	1.15e-199	nodB1	-	-	G	-	-	-	deacetylase
HBDLGIIM_03053	1.45e-198	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HBDLGIIM_03054	4.98e-114	pksA	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_03055	1.55e-123	ymcC	-	-	S	-	-	-	Membrane
HBDLGIIM_03056	2.49e-110	-	-	-	T	-	-	-	universal stress protein
HBDLGIIM_03058	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HBDLGIIM_03059	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HBDLGIIM_03060	3.77e-94	-	-	-	S	-	-	-	AAA ATPase domain
HBDLGIIM_03062	3.86e-142	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HBDLGIIM_03064	6.66e-39	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HBDLGIIM_03065	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HBDLGIIM_03066	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HBDLGIIM_03067	1.26e-271	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HBDLGIIM_03068	1.3e-262	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HBDLGIIM_03069	2.32e-70	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HBDLGIIM_03070	4.1e-257	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
HBDLGIIM_03071	2.95e-205	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HBDLGIIM_03072	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HBDLGIIM_03073	0.0	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
HBDLGIIM_03074	8.13e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HBDLGIIM_03075	4.58e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HBDLGIIM_03077	1.18e-174	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HBDLGIIM_03078	5.99e-21	-	-	-	S	-	-	-	YhzD-like protein
HBDLGIIM_03079	1.12e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_03080	5.62e-276	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HBDLGIIM_03081	7.47e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HBDLGIIM_03082	0.0	yhaN	-	-	L	-	-	-	AAA domain
HBDLGIIM_03083	2.48e-226	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HBDLGIIM_03084	3.48e-44	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HBDLGIIM_03085	1.26e-183	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HBDLGIIM_03086	1.29e-123	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HBDLGIIM_03087	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HBDLGIIM_03088	8.17e-147	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HBDLGIIM_03089	2.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
HBDLGIIM_03090	2.55e-24	-	-	-	-	-	-	-	-
HBDLGIIM_03091	1.43e-100	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HBDLGIIM_03092	2.06e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HBDLGIIM_03093	1.67e-104	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HBDLGIIM_03094	1.82e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HBDLGIIM_03095	1.06e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HBDLGIIM_03096	2.48e-161	ecsC	-	-	S	-	-	-	EcsC protein family
HBDLGIIM_03097	1.78e-285	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HBDLGIIM_03098	3.27e-310	yhfA	-	-	C	-	-	-	membrane
HBDLGIIM_03099	3.1e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HBDLGIIM_03100	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HBDLGIIM_03101	7.35e-259	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HBDLGIIM_03102	4.49e-232	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HBDLGIIM_03103	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HBDLGIIM_03104	3.1e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_03105	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HBDLGIIM_03106	1.39e-233	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBDLGIIM_03108	3.65e-251	yhfE	-	-	G	-	-	-	peptidase M42
HBDLGIIM_03109	3.43e-282	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBDLGIIM_03110	3.85e-179	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HBDLGIIM_03111	3.59e-239	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HBDLGIIM_03112	2.58e-142	yhfK	-	-	GM	-	-	-	NmrA-like family
HBDLGIIM_03113	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HBDLGIIM_03114	6.81e-86	yhfM	-	-	-	-	-	-	-
HBDLGIIM_03115	1.24e-298	yhfN	-	-	O	-	-	-	Peptidase M48
HBDLGIIM_03116	2.72e-262	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HBDLGIIM_03117	7.15e-199	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HBDLGIIM_03118	6.03e-134	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HBDLGIIM_03119	2.48e-253	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HBDLGIIM_03120	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HBDLGIIM_03121	7.56e-116	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HBDLGIIM_03122	5.36e-275	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HBDLGIIM_03123	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HBDLGIIM_03124	1.11e-203	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBDLGIIM_03125	1.91e-42	yhzC	-	-	S	-	-	-	IDEAL
HBDLGIIM_03126	1.09e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HBDLGIIM_03127	1.79e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HBDLGIIM_03128	1.08e-85	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HBDLGIIM_03129	3.33e-118	-	-	-	S	-	-	-	MepB protein
HBDLGIIM_03130	8e-166	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HBDLGIIM_03131	1.23e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HBDLGIIM_03132	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
HBDLGIIM_03133	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBDLGIIM_03134	2.77e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HBDLGIIM_03135	1.68e-78	yhjD	-	-	-	-	-	-	-
HBDLGIIM_03136	9.09e-142	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HBDLGIIM_03137	3.32e-119	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HBDLGIIM_03138	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HBDLGIIM_03139	1.91e-119	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_03140	5.45e-259	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HBDLGIIM_03141	2.64e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_03142	1.57e-141	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
HBDLGIIM_03143	2.96e-121	yhjR	-	-	S	-	-	-	Rubrerythrin
HBDLGIIM_03144	4.08e-159	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HBDLGIIM_03145	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HBDLGIIM_03146	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HBDLGIIM_03147	4.03e-284	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HBDLGIIM_03148	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HBDLGIIM_03149	8.87e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HBDLGIIM_03150	6.66e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HBDLGIIM_03151	1.09e-82	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HBDLGIIM_03152	3e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HBDLGIIM_03153	9.91e-108	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HBDLGIIM_03154	7.71e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HBDLGIIM_03155	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HBDLGIIM_03156	2.25e-11	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HBDLGIIM_03157	8.91e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HBDLGIIM_03158	6.36e-78	yisL	-	-	S	-	-	-	UPF0344 protein
HBDLGIIM_03159	1.78e-122	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HBDLGIIM_03160	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HBDLGIIM_03161	1.33e-171	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HBDLGIIM_03162	1.84e-311	yisQ	-	-	V	-	-	-	Mate efflux family protein
HBDLGIIM_03163	5.28e-203	yisR	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_03164	1.22e-182	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HBDLGIIM_03165	2.08e-198	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HBDLGIIM_03166	2.27e-109	yisT	-	-	S	-	-	-	DinB family
HBDLGIIM_03167	1.24e-107	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HBDLGIIM_03168	3.78e-106	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HBDLGIIM_03169	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HBDLGIIM_03170	2.13e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HBDLGIIM_03171	1.59e-206	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HBDLGIIM_03172	1.04e-219	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
HBDLGIIM_03173	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HBDLGIIM_03174	2.18e-308	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HBDLGIIM_03176	2.24e-202	yitS	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03177	4.62e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBDLGIIM_03178	1.07e-104	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HBDLGIIM_03179	1.5e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HBDLGIIM_03180	1.49e-11	-	-	-	-	-	-	-	-
HBDLGIIM_03181	5.08e-197	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HBDLGIIM_03182	1.06e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HBDLGIIM_03183	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HBDLGIIM_03184	8.23e-106	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HBDLGIIM_03185	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HBDLGIIM_03186	1.18e-121	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HBDLGIIM_03187	1.75e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HBDLGIIM_03188	6.29e-291	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HBDLGIIM_03189	9.59e-171	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HBDLGIIM_03190	2.8e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HBDLGIIM_03191	6.9e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HBDLGIIM_03192	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HBDLGIIM_03193	2.37e-224	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HBDLGIIM_03194	7.21e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
HBDLGIIM_03195	5.24e-33	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HBDLGIIM_03196	3.85e-179	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HBDLGIIM_03197	9.68e-134	yjaV	-	-	-	-	-	-	-
HBDLGIIM_03198	4.67e-213	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HBDLGIIM_03199	6.46e-37	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HBDLGIIM_03200	2.82e-44	yjzB	-	-	-	-	-	-	-
HBDLGIIM_03201	3.78e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBDLGIIM_03202	2.71e-300	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HBDLGIIM_03203	1.84e-190	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HBDLGIIM_03204	4.15e-232	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_03205	7.23e-238	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_03206	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HBDLGIIM_03207	2.45e-218	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBDLGIIM_03208	3.87e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBDLGIIM_03209	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HBDLGIIM_03210	3.56e-234	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HBDLGIIM_03211	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HBDLGIIM_03212	1.46e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBDLGIIM_03213	3.59e-210	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBDLGIIM_03214	1.5e-256	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_03215	4.95e-217	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HBDLGIIM_03216	2.13e-181	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HBDLGIIM_03217	7.01e-94	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HBDLGIIM_03218	4.4e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBDLGIIM_03219	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HBDLGIIM_03220	4.79e-142	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HBDLGIIM_03221	9.78e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HBDLGIIM_03222	6.65e-281	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HBDLGIIM_03223	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HBDLGIIM_03224	3.14e-27	-	-	-	-	-	-	-	-
HBDLGIIM_03225	6.05e-220	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBDLGIIM_03226	1.22e-93	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HBDLGIIM_03227	3.12e-152	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HBDLGIIM_03228	2.55e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03229	2.03e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HBDLGIIM_03230	1.56e-139	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HBDLGIIM_03231	2.07e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBDLGIIM_03232	7.85e-210	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HBDLGIIM_03233	5.27e-184	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HBDLGIIM_03234	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HBDLGIIM_03235	4.88e-178	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBDLGIIM_03236	1.63e-138	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HBDLGIIM_03237	1.42e-271	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HBDLGIIM_03238	5.5e-42	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
HBDLGIIM_03239	1.81e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HBDLGIIM_03240	3.57e-237	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HBDLGIIM_03241	1.68e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HBDLGIIM_03242	6.85e-180	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HBDLGIIM_03243	5.85e-126	yjbX	-	-	S	-	-	-	Spore coat protein
HBDLGIIM_03244	2.1e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HBDLGIIM_03245	4.28e-121	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HBDLGIIM_03246	7.48e-100	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HBDLGIIM_03247	7.2e-37	cotW	-	-	-	ko:K06341	-	ko00000	-
HBDLGIIM_03248	2.67e-68	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HBDLGIIM_03249	1.39e-71	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HBDLGIIM_03252	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HBDLGIIM_03253	2.57e-51	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HBDLGIIM_03254	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HBDLGIIM_03255	4.12e-47	-	-	-	-	-	-	-	-
HBDLGIIM_03256	2.93e-181	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HBDLGIIM_03257	1.31e-159	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HBDLGIIM_03258	2.38e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HBDLGIIM_03259	1.24e-47	-	-	-	K	-	-	-	SpoVT / AbrB like domain
HBDLGIIM_03261	3.59e-212	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HBDLGIIM_03262	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HBDLGIIM_03263	5.92e-142	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HBDLGIIM_03264	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBDLGIIM_03265	6.83e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HBDLGIIM_03266	2.07e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HBDLGIIM_03267	2.73e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HBDLGIIM_03268	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HBDLGIIM_03269	2.02e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HBDLGIIM_03270	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HBDLGIIM_03271	2.11e-220	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HBDLGIIM_03272	1.23e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HBDLGIIM_03273	1.56e-312	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HBDLGIIM_03274	5.45e-138	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HBDLGIIM_03275	6.78e-46	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03276	2.44e-65	-	-	-	S	-	-	-	YlaH-like protein
HBDLGIIM_03277	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HBDLGIIM_03278	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HBDLGIIM_03279	3.48e-63	ylaE	-	-	-	-	-	-	-
HBDLGIIM_03281	8.11e-121	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBDLGIIM_03282	6.07e-58	ylaB	-	-	-	-	-	-	-
HBDLGIIM_03283	2.77e-234	ylaA	-	-	-	-	-	-	-
HBDLGIIM_03284	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HBDLGIIM_03285	1.25e-106	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HBDLGIIM_03286	1.35e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HBDLGIIM_03287	4.57e-31	ykzI	-	-	-	-	-	-	-
HBDLGIIM_03288	8.15e-155	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HBDLGIIM_03289	2.7e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HBDLGIIM_03290	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HBDLGIIM_03291	7.76e-190	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HBDLGIIM_03292	1.38e-59	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HBDLGIIM_03293	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HBDLGIIM_03294	2.43e-300	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HBDLGIIM_03295	1.01e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HBDLGIIM_03296	6.68e-262	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HBDLGIIM_03297	4.74e-267	-	-	-	V	-	-	-	Beta-lactamase
HBDLGIIM_03298	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HBDLGIIM_03299	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_03300	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_03301	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_03302	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_03303	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
HBDLGIIM_03304	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HBDLGIIM_03305	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HBDLGIIM_03306	1.54e-131	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HBDLGIIM_03307	7.91e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HBDLGIIM_03308	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HBDLGIIM_03309	5.26e-188	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HBDLGIIM_03310	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HBDLGIIM_03311	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBDLGIIM_03312	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HBDLGIIM_03313	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HBDLGIIM_03314	5.06e-195	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HBDLGIIM_03315	5.87e-313	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HBDLGIIM_03316	6.37e-60	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HBDLGIIM_03317	2.15e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HBDLGIIM_03318	4.47e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HBDLGIIM_03319	1.2e-302	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HBDLGIIM_03320	7.59e-215	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBDLGIIM_03321	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HBDLGIIM_03322	1.5e-49	ykoA	-	-	-	-	-	-	-
HBDLGIIM_03323	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HBDLGIIM_03324	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HBDLGIIM_03325	1.93e-213	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HBDLGIIM_03326	1.6e-170	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_03327	7.01e-268	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HBDLGIIM_03328	2.9e-158	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_03329	2e-246	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBDLGIIM_03330	8.03e-141	yknW	-	-	S	-	-	-	Yip1 domain
HBDLGIIM_03331	2.06e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HBDLGIIM_03332	3.41e-107	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HBDLGIIM_03333	3.21e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HBDLGIIM_03334	5.6e-309	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HBDLGIIM_03335	4.91e-241	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HBDLGIIM_03336	7.85e-139	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HBDLGIIM_03337	7.24e-218	yknT	-	-	-	ko:K06437	-	ko00000	-
HBDLGIIM_03338	3.04e-126	rok	-	-	K	-	-	-	Repressor of ComK
HBDLGIIM_03339	3.18e-101	ykuV	-	-	CO	-	-	-	thiol-disulfide
HBDLGIIM_03340	2.1e-179	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HBDLGIIM_03341	2.15e-52	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HBDLGIIM_03342	1.14e-275	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HBDLGIIM_03343	2.89e-129	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HBDLGIIM_03344	7.53e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HBDLGIIM_03345	1.67e-220	ykuO	-	-	-	-	-	-	-
HBDLGIIM_03346	3.69e-116	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HBDLGIIM_03347	1.32e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_03348	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
HBDLGIIM_03349	3.09e-35	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HBDLGIIM_03350	5.29e-121	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HBDLGIIM_03351	3.63e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03352	7.72e-297	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HBDLGIIM_03354	3.03e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBDLGIIM_03355	6.33e-198	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HBDLGIIM_03356	5.14e-116	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03357	2.28e-308	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_03358	5.07e-108	ykyB	-	-	S	-	-	-	YkyB-like protein
HBDLGIIM_03359	4.75e-214	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HBDLGIIM_03360	6.38e-15	-	-	-	-	-	-	-	-
HBDLGIIM_03361	1.62e-275	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HBDLGIIM_03362	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_03363	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HBDLGIIM_03364	3.95e-160	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HBDLGIIM_03365	3.9e-66	-	-	-	-	-	-	-	-
HBDLGIIM_03366	3.3e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HBDLGIIM_03367	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HBDLGIIM_03368	4.12e-255	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HBDLGIIM_03369	2.11e-49	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_03370	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBDLGIIM_03371	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HBDLGIIM_03372	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_03373	2.78e-199	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HBDLGIIM_03374	6.8e-223	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_03376	4.71e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HBDLGIIM_03377	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HBDLGIIM_03378	2.1e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
HBDLGIIM_03379	2.66e-306	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HBDLGIIM_03380	1.7e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HBDLGIIM_03381	7.17e-39	-	-	-	-	-	-	-	-
HBDLGIIM_03382	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03383	8.21e-57	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HBDLGIIM_03384	2.57e-170	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HBDLGIIM_03385	2.04e-80	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HBDLGIIM_03386	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HBDLGIIM_03387	1.76e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HBDLGIIM_03388	8.88e-103	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HBDLGIIM_03389	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HBDLGIIM_03390	3.12e-252	-	-	-	-	-	-	-	-
HBDLGIIM_03391	1.81e-230	ykvI	-	-	S	-	-	-	membrane
HBDLGIIM_03392	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HBDLGIIM_03393	1.17e-176	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HBDLGIIM_03394	4.04e-169	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HBDLGIIM_03395	3.91e-100	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HBDLGIIM_03396	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HBDLGIIM_03398	5.24e-124	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HBDLGIIM_03399	1.92e-148	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HBDLGIIM_03400	1.06e-171	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HBDLGIIM_03401	1.3e-287	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HBDLGIIM_03402	1.04e-290	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HBDLGIIM_03403	1.64e-192	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HBDLGIIM_03404	4.05e-286	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HBDLGIIM_03405	2.57e-250	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HBDLGIIM_03407	2.18e-112	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBDLGIIM_03408	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_03409	4.36e-240	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HBDLGIIM_03410	6.21e-32	ykzE	-	-	-	-	-	-	-
HBDLGIIM_03411	6.05e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HBDLGIIM_03412	4.63e-309	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HBDLGIIM_03413	6.35e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HBDLGIIM_03414	3.26e-161	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HBDLGIIM_03415	5.7e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HBDLGIIM_03416	3.6e-250	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HBDLGIIM_03417	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBDLGIIM_03418	4.13e-173	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HBDLGIIM_03419	4.77e-130	ykoX	-	-	S	-	-	-	membrane-associated protein
HBDLGIIM_03420	3.42e-202	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HBDLGIIM_03421	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HBDLGIIM_03422	3.81e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HBDLGIIM_03423	1.98e-105	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HBDLGIIM_03424	5.25e-37	ykoL	-	-	-	-	-	-	-
HBDLGIIM_03425	1.11e-23	-	-	-	-	-	-	-	-
HBDLGIIM_03426	1.01e-68	tnrA	-	-	K	-	-	-	transcriptional
HBDLGIIM_03427	5.43e-157	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HBDLGIIM_03428	1.03e-303	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HBDLGIIM_03429	2.6e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HBDLGIIM_03430	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HBDLGIIM_03431	2.72e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HBDLGIIM_03433	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HBDLGIIM_03434	3.85e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBDLGIIM_03435	6.96e-213	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBDLGIIM_03436	1.61e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_03437	2.78e-223	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HBDLGIIM_03438	7.02e-316	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HBDLGIIM_03439	3.67e-196	ycnC	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_03440	2.68e-172	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HBDLGIIM_03441	5.64e-59	ycnE	-	-	S	-	-	-	Monooxygenase
HBDLGIIM_03442	1.37e-70	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HBDLGIIM_03443	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBDLGIIM_03444	5.34e-288	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBDLGIIM_03445	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HBDLGIIM_03446	5.58e-189	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HBDLGIIM_03447	2.4e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBDLGIIM_03448	1.14e-128	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03449	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HBDLGIIM_03450	4.26e-138	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HBDLGIIM_03451	1.59e-71	-	-	-	-	-	-	-	-
HBDLGIIM_03452	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HBDLGIIM_03453	4.11e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HBDLGIIM_03454	2.84e-264	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HBDLGIIM_03455	2.89e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HBDLGIIM_03457	3.56e-65	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HBDLGIIM_03458	2.49e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HBDLGIIM_03459	1.87e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HBDLGIIM_03460	3.29e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HBDLGIIM_03461	9.41e-175	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HBDLGIIM_03462	1.03e-241	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HBDLGIIM_03463	1.39e-168	kipR	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_03464	7.78e-150	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HBDLGIIM_03466	1.2e-74	yczJ	-	-	S	-	-	-	biosynthesis
HBDLGIIM_03467	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HBDLGIIM_03468	2.57e-221	ycsN	-	-	S	-	-	-	Oxidoreductase
HBDLGIIM_03469	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HBDLGIIM_03470	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HBDLGIIM_03471	1.55e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HBDLGIIM_03472	2.18e-122	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HBDLGIIM_03473	3.72e-145	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HBDLGIIM_03474	1.83e-101	ydaG	-	-	S	-	-	-	general stress protein
HBDLGIIM_03475	1.87e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HBDLGIIM_03476	6.54e-63	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HBDLGIIM_03477	7.97e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HBDLGIIM_03478	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBDLGIIM_03479	1.82e-254	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HBDLGIIM_03480	9.16e-158	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HBDLGIIM_03481	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HBDLGIIM_03482	4.54e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HBDLGIIM_03483	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HBDLGIIM_03484	0.0	ydaO	-	-	E	-	-	-	amino acid
HBDLGIIM_03485	1.08e-97	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HBDLGIIM_03486	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HBDLGIIM_03487	1.21e-62	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HBDLGIIM_03488	2.17e-99	-	-	-	-	-	-	-	-
HBDLGIIM_03490	1.31e-152	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HBDLGIIM_03491	2.61e-53	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HBDLGIIM_03493	3.66e-17	-	-	-	-	-	-	-	-
HBDLGIIM_03495	4.89e-112	-	-	-	-	-	-	-	-
HBDLGIIM_03496	4.14e-129	-	-	-	-	-	-	-	-
HBDLGIIM_03497	2.14e-53	-	-	-	-	-	-	-	-
HBDLGIIM_03498	6.52e-289	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HBDLGIIM_03501	1.95e-45	ydaT	-	-	-	-	-	-	-
HBDLGIIM_03502	2.54e-92	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HBDLGIIM_03503	3.79e-182	ydbA	-	-	P	-	-	-	EcsC protein family
HBDLGIIM_03504	6.55e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HBDLGIIM_03505	1.53e-77	ydbB	-	-	G	-	-	-	Cupin domain
HBDLGIIM_03506	1.28e-82	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HBDLGIIM_03507	3.87e-198	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HBDLGIIM_03508	4.65e-256	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HBDLGIIM_03509	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HBDLGIIM_03510	3.67e-153	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HBDLGIIM_03511	1.59e-286	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBDLGIIM_03512	4.98e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
HBDLGIIM_03513	1.95e-220	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HBDLGIIM_03514	2.44e-167	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HBDLGIIM_03515	7.67e-69	ydbL	-	-	-	-	-	-	-
HBDLGIIM_03516	5.29e-262	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HBDLGIIM_03517	1.13e-15	-	-	-	S	-	-	-	Fur-regulated basic protein B
HBDLGIIM_03518	6.58e-14	-	-	-	S	-	-	-	Fur-regulated basic protein A
HBDLGIIM_03519	9.92e-161	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBDLGIIM_03520	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
HBDLGIIM_03521	7.23e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HBDLGIIM_03522	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HBDLGIIM_03523	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HBDLGIIM_03524	6.24e-96	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HBDLGIIM_03525	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HBDLGIIM_03526	1.71e-137	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HBDLGIIM_03527	1.37e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HBDLGIIM_03528	1.57e-235	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HBDLGIIM_03529	2.81e-279	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBDLGIIM_03530	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HBDLGIIM_03531	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HBDLGIIM_03532	3.01e-186	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HBDLGIIM_03533	6.28e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HBDLGIIM_03534	1.73e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HBDLGIIM_03535	1.25e-241	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HBDLGIIM_03536	9.77e-71	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HBDLGIIM_03537	7.1e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HBDLGIIM_03538	1.14e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBDLGIIM_03539	5.75e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HBDLGIIM_03540	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HBDLGIIM_03541	1.78e-21	-	-	-	-	-	-	-	-
HBDLGIIM_03542	1.74e-75	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HBDLGIIM_03551	0.0	-	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Transporter
HBDLGIIM_03552	3.95e-108	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
HBDLGIIM_03553	5.23e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HBDLGIIM_03554	3.46e-84	-	-	-	S	-	-	-	YjbR
HBDLGIIM_03555	5.6e-87	ywnA	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_03556	1.56e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HBDLGIIM_03557	3.87e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HBDLGIIM_03558	1.4e-100	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HBDLGIIM_03559	2.63e-53	yrkD	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03560	4.62e-107	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
HBDLGIIM_03561	2.02e-76	-	-	-	P	-	-	-	Rhodanese Homology Domain
HBDLGIIM_03562	1.59e-121	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
HBDLGIIM_03563	1.37e-252	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
HBDLGIIM_03564	6.46e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
HBDLGIIM_03565	1.25e-166	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HBDLGIIM_03566	4.07e-75	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HBDLGIIM_03567	7.92e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HBDLGIIM_03568	6.75e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HBDLGIIM_03569	2.81e-231	-	-	-	S	-	-	-	Patatin-like phospholipase
HBDLGIIM_03570	5.2e-103	-	-	-	S	-	-	-	DinB superfamily
HBDLGIIM_03571	2.39e-146	dpaL	4.3.1.15	-	E	ko:K01751	-	ko00000,ko01000	Pyridoxal-phosphate dependent enzyme
HBDLGIIM_03572	4.08e-85	-	-	-	K	-	-	-	COG1802 Transcriptional regulators
HBDLGIIM_03573	1.81e-51	-	-	-	J	-	-	-	Endoribonuclease L-PSP
HBDLGIIM_03574	8.7e-174	-	-	-	E	ko:K03837	-	ko00000,ko02000	Serine transporter
HBDLGIIM_03575	2.03e-204	-	-	-	E	-	-	-	Peptidase dimerisation domain
HBDLGIIM_03576	9.42e-160	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HBDLGIIM_03577	1.41e-221	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HBDLGIIM_03578	8.68e-297	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBDLGIIM_03579	2.27e-244	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HBDLGIIM_03580	3.77e-68	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HBDLGIIM_03583	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HBDLGIIM_03584	5.55e-216	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HBDLGIIM_03585	1.01e-252	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
HBDLGIIM_03587	3.85e-130	yrkC	-	-	G	-	-	-	Cupin domain
HBDLGIIM_03588	9.97e-53	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
HBDLGIIM_03589	2.32e-190	dapA7	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HBDLGIIM_03591	1.09e-249	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HBDLGIIM_03592	2.4e-68	ydeH	-	-	-	-	-	-	-
HBDLGIIM_03593	4.86e-211	-	-	-	S	-	-	-	Sodium Bile acid symporter family
HBDLGIIM_03594	1.83e-257	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HBDLGIIM_03595	7.29e-87	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HBDLGIIM_03596	1.2e-282	nhaC_1	-	-	C	-	-	-	antiporter
HBDLGIIM_03597	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HBDLGIIM_03598	9.88e-145	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_03600	2.24e-139	-	-	-	I	-	-	-	Ribosomal RNA adenine dimethylase
HBDLGIIM_03601	1.06e-159	-	-	-	T	-	-	-	Transcriptional regulator
HBDLGIIM_03602	4.38e-244	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HBDLGIIM_03603	1.43e-134	-	-	-	S	-	-	-	SNARE associated Golgi protein
HBDLGIIM_03604	4.35e-250	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HBDLGIIM_03605	2.43e-132	ydeS	-	-	K	-	-	-	Transcriptional regulator
HBDLGIIM_03606	3.04e-201	ydeK	-	-	EG	-	-	-	-transporter
HBDLGIIM_03607	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HBDLGIIM_03608	5.95e-65	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HBDLGIIM_03609	1.64e-34	yraE	-	-	-	ko:K06440	-	ko00000	-
HBDLGIIM_03610	3.04e-282	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HBDLGIIM_03611	8.22e-85	yraF	-	-	M	-	-	-	Spore coat protein
HBDLGIIM_03612	3.45e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
HBDLGIIM_03613	2.44e-275	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_03614	2.4e-143	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HBDLGIIM_03615	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HBDLGIIM_03616	2.4e-171	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HBDLGIIM_03617	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HBDLGIIM_03618	5.28e-127	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HBDLGIIM_03619	1.74e-191	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HBDLGIIM_03620	2.68e-248	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HBDLGIIM_03621	5.54e-268	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HBDLGIIM_03622	1.17e-289	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HBDLGIIM_03623	2.24e-200	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HBDLGIIM_03624	3.66e-157	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HBDLGIIM_03625	2.95e-106	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HBDLGIIM_03626	5.9e-193	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HBDLGIIM_03627	2.1e-190	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HBDLGIIM_03630	4.1e-84	hxlR	-	-	K	-	-	-	transcriptional
HBDLGIIM_03631	5.21e-138	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HBDLGIIM_03632	8.93e-124	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HBDLGIIM_03633	1.88e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HBDLGIIM_03634	5.81e-92	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HBDLGIIM_03635	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HBDLGIIM_03636	3.31e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HBDLGIIM_03637	1.49e-93	yckC	-	-	S	-	-	-	membrane
HBDLGIIM_03638	8.73e-282	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HBDLGIIM_03639	1.73e-290	yciC	-	-	S	-	-	-	GTPases (G3E family)
HBDLGIIM_03640	5.75e-285	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HBDLGIIM_03641	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
HBDLGIIM_03642	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBDLGIIM_03643	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBDLGIIM_03644	5.95e-75	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HBDLGIIM_03645	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HBDLGIIM_03646	1.36e-241	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HBDLGIIM_03647	8.26e-290	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HBDLGIIM_03648	3.14e-311	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBDLGIIM_03649	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HBDLGIIM_03650	2.75e-216	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HBDLGIIM_03651	3.05e-189	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HBDLGIIM_03652	5.69e-234	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HBDLGIIM_03653	8.64e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HBDLGIIM_03654	3.9e-303	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HBDLGIIM_03655	3.43e-191	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
HBDLGIIM_03656	3.89e-140	tmrB	-	-	S	-	-	-	AAA domain
HBDLGIIM_03657	2.47e-07	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HBDLGIIM_03658	1.29e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HBDLGIIM_03659	3.22e-146	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HBDLGIIM_03660	3.29e-308	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HBDLGIIM_03661	1.03e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HBDLGIIM_03662	1.11e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HBDLGIIM_03663	2.82e-100	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_03664	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HBDLGIIM_03665	2.69e-227	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HBDLGIIM_03666	1.2e-29	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HBDLGIIM_03667	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HBDLGIIM_03668	2.55e-105	ycgB	-	-	-	-	-	-	-
HBDLGIIM_03669	9.35e-293	ycgA	-	-	S	-	-	-	Membrane
HBDLGIIM_03670	1.31e-269	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HBDLGIIM_03671	2.34e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HBDLGIIM_03672	2.45e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HBDLGIIM_03673	7.71e-294	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HBDLGIIM_03674	2.13e-275	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HBDLGIIM_03675	1.17e-246	yceH	-	-	P	-	-	-	Belongs to the TelA family
HBDLGIIM_03676	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HBDLGIIM_03677	2.12e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HBDLGIIM_03678	2.46e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HBDLGIIM_03679	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HBDLGIIM_03680	3.34e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HBDLGIIM_03681	1.99e-236	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBDLGIIM_03682	1.19e-174	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HBDLGIIM_03683	5.69e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HBDLGIIM_03684	7.35e-214	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HBDLGIIM_03685	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HBDLGIIM_03686	3.67e-180	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HBDLGIIM_03687	2.01e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HBDLGIIM_03688	6.25e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HBDLGIIM_03689	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBDLGIIM_03690	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBDLGIIM_03691	1.54e-224	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HBDLGIIM_03692	1.32e-219	yccK	-	-	C	-	-	-	Aldo keto reductase
HBDLGIIM_03693	3.11e-248	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HBDLGIIM_03694	2.4e-136	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HBDLGIIM_03695	8.48e-231	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HBDLGIIM_03697	3.64e-129	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HBDLGIIM_03698	2.5e-313	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HBDLGIIM_03699	1.65e-264	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HBDLGIIM_03700	1.4e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HBDLGIIM_03701	4.75e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HBDLGIIM_03702	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HBDLGIIM_03703	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HBDLGIIM_03704	1.75e-100	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HBDLGIIM_03705	1.63e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HBDLGIIM_03706	5.89e-36	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HBDLGIIM_03707	5.81e-221	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HBDLGIIM_03708	1.47e-277	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HBDLGIIM_03709	1.11e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HBDLGIIM_03710	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HBDLGIIM_03711	4.14e-230	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HBDLGIIM_03712	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HBDLGIIM_03713	4.13e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HBDLGIIM_03714	8.22e-272	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBDLGIIM_03715	5.76e-245	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HBDLGIIM_03716	6.1e-55	ybfN	-	-	-	-	-	-	-
HBDLGIIM_03717	8.74e-194	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HBDLGIIM_03718	4.26e-113	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HBDLGIIM_03719	1.56e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBDLGIIM_03720	1.61e-271	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HBDLGIIM_03721	4.3e-255	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HBDLGIIM_03722	1.69e-107	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HBDLGIIM_03723	2.99e-46	-	-	-	-	-	-	-	-
HBDLGIIM_03724	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HBDLGIIM_03726	8.21e-267	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HBDLGIIM_03727	5.8e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HBDLGIIM_03728	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HBDLGIIM_03729	4.23e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HBDLGIIM_03730	2.09e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HBDLGIIM_03733	1.13e-16	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HBDLGIIM_03734	7.42e-53	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HBDLGIIM_03735	0.0	ybeC	-	-	E	-	-	-	amino acid
HBDLGIIM_03736	7.84e-55	ybyB	-	-	-	-	-	-	-
HBDLGIIM_03737	5.91e-143	yqeB	-	-	-	-	-	-	-
HBDLGIIM_03738	2.91e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HBDLGIIM_03739	8.99e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
HBDLGIIM_03740	2.34e-35	-	-	-	-	-	-	-	-
HBDLGIIM_03741	3.78e-252	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HBDLGIIM_03742	1.29e-262	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HBDLGIIM_03743	6.21e-214	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HBDLGIIM_03744	7.97e-139	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HBDLGIIM_03745	1.57e-258	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
HBDLGIIM_03746	2.64e-119	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HBDLGIIM_03747	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HBDLGIIM_03748	2.9e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_03749	1.41e-67	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HBDLGIIM_03750	4.26e-135	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HBDLGIIM_03751	2.08e-206	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
HBDLGIIM_03752	8.61e-165	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HBDLGIIM_03753	5.7e-125	ybdN	-	-	-	-	-	-	-
HBDLGIIM_03754	3.24e-138	-	-	-	S	-	-	-	ABC-2 family transporter protein
HBDLGIIM_03755	5.87e-197	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HBDLGIIM_03756	6.87e-230	ydaD_3	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HBDLGIIM_03757	4.8e-274	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HBDLGIIM_03758	1.22e-47	-	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HBDLGIIM_03759	2.61e-309	-	-	-	-	-	-	-	-
HBDLGIIM_03760	6.06e-221	-	-	-	L	-	-	-	Tn7-like transposition protein D
HBDLGIIM_03761	1.89e-124	-	-	-	L	-	-	-	Tn7-like transposition protein D
HBDLGIIM_03762	0.0	-	-	-	L	-	-	-	Bacterial TniB protein
HBDLGIIM_03763	0.0	-	-	-	L	-	-	-	Mu transposase, C-terminal
HBDLGIIM_03764	1.98e-162	tnsA	-	-	L	-	-	-	TnsA endonuclease N terminal
HBDLGIIM_03765	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HBDLGIIM_03766	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBDLGIIM_03767	3.12e-297	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03768	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HBDLGIIM_03769	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HBDLGIIM_03770	1.08e-125	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HBDLGIIM_03776	1.11e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HBDLGIIM_03777	6.11e-111	ybbJ	-	-	J	-	-	-	acetyltransferase
HBDLGIIM_03778	5.7e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HBDLGIIM_03779	1.61e-307	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HBDLGIIM_03780	1.13e-311	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HBDLGIIM_03781	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HBDLGIIM_03782	4.51e-300	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HBDLGIIM_03783	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HBDLGIIM_03784	2.98e-220	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HBDLGIIM_03785	1.8e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBDLGIIM_03786	1.37e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBDLGIIM_03787	6.71e-144	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HBDLGIIM_03788	2.85e-220	ybaS	-	-	S	-	-	-	Na -dependent transporter
HBDLGIIM_03789	9.57e-289	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HBDLGIIM_03790	6.88e-257	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HBDLGIIM_03791	1.34e-231	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
HBDLGIIM_03792	2.57e-313	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBDLGIIM_03793	1.06e-277	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HBDLGIIM_03794	5.77e-121	-	-	-	S	-	-	-	A nuclease of the HNH/ENDO VII superfamily with conserved WHH
HBDLGIIM_03795	2.55e-123	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HBDLGIIM_03797	1.08e-54	-	-	-	-	-	-	-	-
HBDLGIIM_03799	5.75e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HBDLGIIM_03800	4.15e-258	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBDLGIIM_03801	1.12e-150	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
HBDLGIIM_03802	9.28e-07	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HBDLGIIM_03803	1.3e-85	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HBDLGIIM_03805	2.6e-124	yvgO	-	-	-	-	-	-	-
HBDLGIIM_03807	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HBDLGIIM_03809	1.43e-100	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HBDLGIIM_03810	3.5e-183	yndL	-	-	S	-	-	-	Replication protein
HBDLGIIM_03811	4.12e-10	-	-	-	-	-	-	-	-
HBDLGIIM_03812	6.02e-183	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HBDLGIIM_03813	5.09e-92	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HBDLGIIM_03815	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBDLGIIM_03816	1.01e-67	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HBDLGIIM_03817	1.23e-143	yneB	-	-	L	-	-	-	resolvase
HBDLGIIM_03818	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HBDLGIIM_03819	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBDLGIIM_03820	1.79e-105	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HBDLGIIM_03821	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HBDLGIIM_03822	1.97e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HBDLGIIM_03823	4.47e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HBDLGIIM_03824	2.47e-76	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HBDLGIIM_03825	6.5e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HBDLGIIM_03826	4.83e-98	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HBDLGIIM_03827	7.01e-82	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HBDLGIIM_03828	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HBDLGIIM_03829	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HBDLGIIM_03830	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBDLGIIM_03831	9.94e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBDLGIIM_03833	4.24e-45	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HBDLGIIM_03834	2.94e-97	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HBDLGIIM_03835	1.91e-70	yneQ	-	-	-	-	-	-	-
HBDLGIIM_03836	2.67e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HBDLGIIM_03837	1.83e-120	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HBDLGIIM_03838	9.94e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HBDLGIIM_03839	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBDLGIIM_03840	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBDLGIIM_03841	3.14e-19	-	-	-	-	-	-	-	-
HBDLGIIM_03842	1.82e-63	ynfC	-	-	-	-	-	-	-
HBDLGIIM_03843	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HBDLGIIM_03844	1.83e-230	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HBDLGIIM_03845	1.35e-238	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HBDLGIIM_03846	3.05e-146	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HBDLGIIM_03847	2.29e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HBDLGIIM_03848	6.84e-190	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBDLGIIM_03849	1.23e-231	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HBDLGIIM_03850	4.57e-286	exuT	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	Sugar (and other) transporter
HBDLGIIM_03851	6.96e-200	yndG	-	-	S	-	-	-	DoxX-like family
HBDLGIIM_03852	6.95e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HBDLGIIM_03853	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HBDLGIIM_03854	2.25e-09	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
HBDLGIIM_03856	8.76e-247	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
HBDLGIIM_03857	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
HBDLGIIM_03858	4.98e-68	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
HBDLGIIM_03859	4.85e-312	-	-	-	T	-	-	-	Histidine kinase
HBDLGIIM_03860	4.61e-165	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HBDLGIIM_03861	3.94e-194	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
HBDLGIIM_03862	1.92e-85	ynfF	3.2.1.136	GH5	G	ko:K15924	-	ko00000,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
HBDLGIIM_03863	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HBDLGIIM_03864	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_03865	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_03866	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_03867	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_03868	1.12e-286	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HBDLGIIM_03869	2.35e-174	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HBDLGIIM_03870	4.5e-157	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HBDLGIIM_03871	5.16e-161	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBDLGIIM_03872	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HBDLGIIM_03873	1.46e-281	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HBDLGIIM_03874	1.12e-246	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HBDLGIIM_03875	2.49e-165	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HBDLGIIM_03876	6.27e-270	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HBDLGIIM_03877	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HBDLGIIM_03878	6.12e-184	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HBDLGIIM_03879	1.31e-94	yngA	-	-	S	-	-	-	membrane
HBDLGIIM_03880	8.78e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HBDLGIIM_03881	5.33e-135	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HBDLGIIM_03882	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HBDLGIIM_03883	1.01e-177	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HBDLGIIM_03884	2.98e-215	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HBDLGIIM_03885	2.77e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HBDLGIIM_03886	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HBDLGIIM_03887	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HBDLGIIM_03888	5.35e-268	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HBDLGIIM_03889	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HBDLGIIM_03890	1.38e-84	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HBDLGIIM_03891	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
HBDLGIIM_03892	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_03893	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBDLGIIM_03894	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HBDLGIIM_03895	5.76e-241	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HBDLGIIM_03896	7.44e-312	yoeA	-	-	V	-	-	-	MATE efflux family protein
HBDLGIIM_03897	3.68e-125	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HBDLGIIM_03899	3.97e-125	-	-	-	L	-	-	-	Integrase
HBDLGIIM_03900	6.69e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HBDLGIIM_03901	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HBDLGIIM_03902	4.77e-118	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
HBDLGIIM_03903	4.64e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HBDLGIIM_03904	0.0	-	-	-	I	-	-	-	PLD-like domain
HBDLGIIM_03905	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HBDLGIIM_03906	5.62e-193	-	-	-	S	-	-	-	membrane
HBDLGIIM_03907	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HBDLGIIM_03908	6.17e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HBDLGIIM_03909	5.81e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HBDLGIIM_03910	2.89e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HBDLGIIM_03911	4.82e-103	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HBDLGIIM_03912	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HBDLGIIM_03913	2.14e-84	-	-	-	S	-	-	-	TIGRFAM germination protein, Ger(x)C family
HBDLGIIM_03914	7.31e-32	-	-	-	EG	-	-	-	Spore germination protein
HBDLGIIM_03915	8.22e-41	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HBDLGIIM_03916	1.41e-103	-	-	-	-	-	-	-	-
HBDLGIIM_03917	2.84e-123	tnpR	-	-	L	-	-	-	resolvase
HBDLGIIM_03918	1.51e-113	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
HBDLGIIM_03919	7.03e-272	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
HBDLGIIM_03920	7.57e-295	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
HBDLGIIM_03921	6.56e-151	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_03922	8.44e-238	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HBDLGIIM_03923	8.34e-65	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HBDLGIIM_03924	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HBDLGIIM_03925	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HBDLGIIM_03926	1.4e-203	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HBDLGIIM_03927	4e-259	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HBDLGIIM_03928	3.42e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBDLGIIM_03929	8.13e-82	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HBDLGIIM_03930	1.73e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HBDLGIIM_03931	5.9e-57	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HBDLGIIM_03932	5.84e-174	yoxB	-	-	-	-	-	-	-
HBDLGIIM_03933	4.46e-261	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HBDLGIIM_03934	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HBDLGIIM_03935	2.45e-245	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBDLGIIM_03936	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBDLGIIM_03937	7.35e-35	yoaF	-	-	-	-	-	-	-
HBDLGIIM_03939	9.04e-126	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HBDLGIIM_03940	2.42e-59	-	-	-	-	-	-	-	-
HBDLGIIM_03941	1.3e-100	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HBDLGIIM_03942	1.5e-163	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH