ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IGBBEFOO_00001 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IGBBEFOO_00003 3.47e-205 ybaS - - S - - - Na -dependent transporter
IGBBEFOO_00004 4.01e-184 ybbA - - S ko:K07017 - ko00000 Putative esterase
IGBBEFOO_00005 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_00006 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_00007 9.23e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
IGBBEFOO_00008 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
IGBBEFOO_00009 3.6e-306 ybbC - - S - - - protein conserved in bacteria
IGBBEFOO_00010 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
IGBBEFOO_00011 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
IGBBEFOO_00012 7.29e-304 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_00013 3.82e-194 ybbH - - K - - - transcriptional
IGBBEFOO_00014 4.04e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IGBBEFOO_00015 1.55e-114 ybbJ - - J - - - acetyltransferase
IGBBEFOO_00016 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
IGBBEFOO_00022 1.6e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IGBBEFOO_00023 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IGBBEFOO_00024 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IGBBEFOO_00025 4.16e-292 ybbR - - S - - - protein conserved in bacteria
IGBBEFOO_00026 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IGBBEFOO_00027 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IGBBEFOO_00028 3.67e-227 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IGBBEFOO_00029 2.25e-157 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
IGBBEFOO_00030 4.49e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IGBBEFOO_00031 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IGBBEFOO_00032 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
IGBBEFOO_00033 2.51e-125 ybcF - - P - - - carbonic anhydrase
IGBBEFOO_00034 5.59e-64 - - - - - - - -
IGBBEFOO_00035 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
IGBBEFOO_00036 9.45e-67 - - - K - - - Helix-turn-helix domain
IGBBEFOO_00037 1.14e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
IGBBEFOO_00039 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
IGBBEFOO_00040 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
IGBBEFOO_00041 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IGBBEFOO_00042 3.99e-313 skfF - - S - - - ABC transporter
IGBBEFOO_00043 3.88e-118 - - - C - - - HEAT repeats
IGBBEFOO_00044 5.88e-103 - - - CO - - - Thioredoxin-like domain
IGBBEFOO_00045 8.07e-233 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IGBBEFOO_00046 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
IGBBEFOO_00047 4.12e-221 - - - T - - - His Kinase A (phospho-acceptor) domain
IGBBEFOO_00049 2.49e-181 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
IGBBEFOO_00050 6.61e-196 ybdN - - - - - - -
IGBBEFOO_00051 1.19e-278 ybdO - - S - - - Domain of unknown function (DUF4885)
IGBBEFOO_00052 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IGBBEFOO_00053 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
IGBBEFOO_00054 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
IGBBEFOO_00055 3.86e-195 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
IGBBEFOO_00056 9.97e-317 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
IGBBEFOO_00057 1.11e-54 ybyB - - - - - - -
IGBBEFOO_00058 0.0 ybeC - - E - - - amino acid
IGBBEFOO_00059 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
IGBBEFOO_00060 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
IGBBEFOO_00061 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
IGBBEFOO_00062 8.93e-220 ybfA - - K - - - FR47-like protein
IGBBEFOO_00063 2.36e-287 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_00065 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
IGBBEFOO_00066 5.27e-208 ybfH - - EG - - - EamA-like transporter family
IGBBEFOO_00067 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
IGBBEFOO_00068 5.85e-274 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IGBBEFOO_00069 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
IGBBEFOO_00071 2.02e-216 - - - S - - - Alpha/beta hydrolase family
IGBBEFOO_00072 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IGBBEFOO_00073 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
IGBBEFOO_00074 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IGBBEFOO_00075 2.33e-61 ybfN - - - - - - -
IGBBEFOO_00076 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
IGBBEFOO_00077 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_00078 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
IGBBEFOO_00079 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IGBBEFOO_00080 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_00081 7.72e-177 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IGBBEFOO_00082 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IGBBEFOO_00084 9.84e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IGBBEFOO_00085 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IGBBEFOO_00086 2.23e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
IGBBEFOO_00087 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IGBBEFOO_00088 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IGBBEFOO_00089 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_00090 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
IGBBEFOO_00091 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
IGBBEFOO_00092 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IGBBEFOO_00093 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_00094 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IGBBEFOO_00095 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
IGBBEFOO_00096 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IGBBEFOO_00097 4.64e-227 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
IGBBEFOO_00098 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
IGBBEFOO_00099 1.87e-220 eamA1 - - EG - - - spore germination
IGBBEFOO_00100 6.64e-162 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_00101 1.66e-218 ycbM - - T - - - Histidine kinase
IGBBEFOO_00102 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_00103 4.25e-150 - - - S - - - ABC-2 family transporter protein
IGBBEFOO_00104 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
IGBBEFOO_00105 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
IGBBEFOO_00106 4.66e-175 ycbR - - T - - - vWA found in TerF C terminus
IGBBEFOO_00107 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
IGBBEFOO_00108 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IGBBEFOO_00109 7.6e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IGBBEFOO_00110 2.52e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IGBBEFOO_00111 3.48e-268 ycbU - - E - - - Selenocysteine lyase
IGBBEFOO_00112 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
IGBBEFOO_00113 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IGBBEFOO_00114 8.74e-260 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IGBBEFOO_00115 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IGBBEFOO_00116 4.32e-78 - - - S - - - RDD family
IGBBEFOO_00117 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
IGBBEFOO_00118 9.56e-217 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IGBBEFOO_00119 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
IGBBEFOO_00120 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IGBBEFOO_00121 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IGBBEFOO_00122 5.83e-223 yccK - - C - - - Aldo keto reductase
IGBBEFOO_00123 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
IGBBEFOO_00124 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IGBBEFOO_00125 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IGBBEFOO_00126 3.91e-125 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IGBBEFOO_00127 1.42e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IGBBEFOO_00128 5.87e-181 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
IGBBEFOO_00129 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IGBBEFOO_00130 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IGBBEFOO_00131 1.99e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IGBBEFOO_00132 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IGBBEFOO_00133 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IGBBEFOO_00134 6.69e-72 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
IGBBEFOO_00135 1.45e-51 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
IGBBEFOO_00136 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IGBBEFOO_00137 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IGBBEFOO_00138 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
IGBBEFOO_00139 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
IGBBEFOO_00140 2.96e-245 yceH - - P - - - Belongs to the TelA family
IGBBEFOO_00141 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
IGBBEFOO_00142 1.17e-267 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
IGBBEFOO_00143 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IGBBEFOO_00144 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
IGBBEFOO_00145 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IGBBEFOO_00146 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IGBBEFOO_00147 2.5e-279 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
IGBBEFOO_00148 0.0 ycgA - - S - - - Membrane
IGBBEFOO_00149 1.25e-127 ycgB - - - - - - -
IGBBEFOO_00150 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IGBBEFOO_00151 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IGBBEFOO_00152 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IGBBEFOO_00153 0.0 mdr - - EGP - - - the major facilitator superfamily
IGBBEFOO_00154 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGBBEFOO_00155 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
IGBBEFOO_00156 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IGBBEFOO_00157 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IGBBEFOO_00158 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
IGBBEFOO_00159 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IGBBEFOO_00160 1.31e-140 tmrB - - S - - - AAA domain
IGBBEFOO_00161 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IGBBEFOO_00162 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
IGBBEFOO_00163 2.05e-230 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
IGBBEFOO_00164 1.15e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
IGBBEFOO_00165 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
IGBBEFOO_00166 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IGBBEFOO_00167 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IGBBEFOO_00168 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IGBBEFOO_00169 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
IGBBEFOO_00170 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
IGBBEFOO_00171 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
IGBBEFOO_00172 4.74e-209 ycgS - - I - - - alpha/beta hydrolase fold
IGBBEFOO_00173 8.9e-247 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IGBBEFOO_00174 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IGBBEFOO_00175 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
IGBBEFOO_00176 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IGBBEFOO_00177 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IGBBEFOO_00178 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
IGBBEFOO_00179 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IGBBEFOO_00180 1.05e-222 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
IGBBEFOO_00181 2.56e-141 - - - M - - - ErfK YbiS YcfS YnhG
IGBBEFOO_00182 6.78e-291 yciC - - S - - - GTPases (G3E family)
IGBBEFOO_00183 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IGBBEFOO_00184 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IGBBEFOO_00187 5.95e-101 yckC - - S - - - membrane
IGBBEFOO_00188 3.53e-69 yckD - - S - - - Protein of unknown function (DUF2680)
IGBBEFOO_00189 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IGBBEFOO_00190 7.06e-93 nin - - S - - - Competence protein J (ComJ)
IGBBEFOO_00191 4.78e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
IGBBEFOO_00192 6.52e-269 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IGBBEFOO_00193 1.38e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
IGBBEFOO_00194 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
IGBBEFOO_00195 6.05e-86 hxlR - - K - - - transcriptional
IGBBEFOO_00196 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGBBEFOO_00197 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGBBEFOO_00198 5.49e-78 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IGBBEFOO_00199 9.06e-186 - - - S ko:K19279 - ko00000,ko01000,ko01504 Domain of unknown function (DUF4111)
IGBBEFOO_00200 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IGBBEFOO_00201 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
IGBBEFOO_00202 1.38e-291 - - - EGP - - - Major Facilitator Superfamily
IGBBEFOO_00203 1.61e-126 - - - S - - - YcxB-like protein
IGBBEFOO_00204 1.77e-209 ycxC - - EG - - - EamA-like transporter family
IGBBEFOO_00205 0.0 ycxD - - K - - - GntR family transcriptional regulator
IGBBEFOO_00206 1.37e-144 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
IGBBEFOO_00207 3.04e-148 yczE - - S ko:K07149 - ko00000 membrane
IGBBEFOO_00208 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IGBBEFOO_00209 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IGBBEFOO_00210 1.5e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IGBBEFOO_00211 9.2e-210 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
IGBBEFOO_00212 2.33e-142 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IGBBEFOO_00213 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IGBBEFOO_00214 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
IGBBEFOO_00215 3.05e-109 yclD - - - - - - -
IGBBEFOO_00216 5.12e-207 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
IGBBEFOO_00217 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
IGBBEFOO_00218 0.0 yclG - - M - - - Pectate lyase superfamily protein
IGBBEFOO_00220 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
IGBBEFOO_00221 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
IGBBEFOO_00222 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
IGBBEFOO_00223 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IGBBEFOO_00224 5.59e-280 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
IGBBEFOO_00225 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_00226 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IGBBEFOO_00227 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IGBBEFOO_00229 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IGBBEFOO_00230 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IGBBEFOO_00231 5.42e-206 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_00232 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_00233 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_00234 4.98e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
IGBBEFOO_00235 0.0 ycnB - - EGP - - - the major facilitator superfamily
IGBBEFOO_00236 1.76e-199 ycnC - - K - - - Transcriptional regulator
IGBBEFOO_00237 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IGBBEFOO_00238 1.68e-60 ycnE - - S - - - Monooxygenase
IGBBEFOO_00239 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IGBBEFOO_00240 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IGBBEFOO_00241 2.4e-313 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IGBBEFOO_00242 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IGBBEFOO_00243 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
IGBBEFOO_00244 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_00245 1.07e-138 ycnI - - S - - - protein conserved in bacteria
IGBBEFOO_00246 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
IGBBEFOO_00247 5.18e-139 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IGBBEFOO_00248 1.34e-74 - - - - - - - -
IGBBEFOO_00249 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
IGBBEFOO_00250 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IGBBEFOO_00251 3.77e-269 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
IGBBEFOO_00252 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
IGBBEFOO_00254 6.21e-97 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IGBBEFOO_00255 2.64e-147 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
IGBBEFOO_00256 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
IGBBEFOO_00258 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IGBBEFOO_00259 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
IGBBEFOO_00260 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
IGBBEFOO_00261 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
IGBBEFOO_00262 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
IGBBEFOO_00263 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
IGBBEFOO_00264 3.8e-171 kipR - - K - - - Transcriptional regulator
IGBBEFOO_00265 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
IGBBEFOO_00267 7.67e-66 yczJ - - S - - - biosynthesis
IGBBEFOO_00268 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
IGBBEFOO_00269 3.26e-224 ycsN - - S - - - Oxidoreductase
IGBBEFOO_00270 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
IGBBEFOO_00271 0.0 ydaB - - IQ - - - acyl-CoA ligase
IGBBEFOO_00272 6.05e-129 ydaC - - Q - - - Methyltransferase domain
IGBBEFOO_00273 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_00274 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
IGBBEFOO_00275 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IGBBEFOO_00276 5.24e-101 ydaG - - S - - - general stress protein
IGBBEFOO_00277 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IGBBEFOO_00278 1.88e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
IGBBEFOO_00279 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IGBBEFOO_00280 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IGBBEFOO_00281 3.08e-267 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
IGBBEFOO_00282 1.14e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
IGBBEFOO_00283 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
IGBBEFOO_00284 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
IGBBEFOO_00285 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
IGBBEFOO_00286 0.0 ydaO - - E - - - amino acid
IGBBEFOO_00287 3.75e-103 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IGBBEFOO_00288 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IGBBEFOO_00289 2.14e-53 - - - - - - - -
IGBBEFOO_00290 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IGBBEFOO_00291 1.67e-42 ydaS - - S - - - membrane
IGBBEFOO_00292 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IGBBEFOO_00293 1.06e-190 ydbA - - P - - - EcsC protein family
IGBBEFOO_00294 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
IGBBEFOO_00295 7.58e-79 ydbB - - G - - - Cupin domain
IGBBEFOO_00296 5.41e-84 ydbC - - S - - - Domain of unknown function (DUF4937
IGBBEFOO_00297 1.35e-198 ydbD - - P ko:K07217 - ko00000 Catalase
IGBBEFOO_00298 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IGBBEFOO_00299 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IGBBEFOO_00300 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IGBBEFOO_00301 4.43e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IGBBEFOO_00302 3.25e-231 ydbI - - S - - - AI-2E family transporter
IGBBEFOO_00303 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_00304 7.34e-160 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IGBBEFOO_00305 9.32e-70 ydbL - - - - - - -
IGBBEFOO_00306 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
IGBBEFOO_00307 1.49e-26 - - - S - - - Fur-regulated basic protein B
IGBBEFOO_00309 1.91e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IGBBEFOO_00310 4.19e-75 ydbP - - CO - - - Thioredoxin
IGBBEFOO_00311 3.07e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IGBBEFOO_00312 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IGBBEFOO_00313 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IGBBEFOO_00314 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
IGBBEFOO_00315 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
IGBBEFOO_00316 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
IGBBEFOO_00317 1.95e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IGBBEFOO_00318 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
IGBBEFOO_00319 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IGBBEFOO_00320 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IGBBEFOO_00321 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
IGBBEFOO_00322 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
IGBBEFOO_00323 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
IGBBEFOO_00324 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IGBBEFOO_00325 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
IGBBEFOO_00326 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
IGBBEFOO_00327 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IGBBEFOO_00328 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGBBEFOO_00329 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
IGBBEFOO_00333 1.32e-106 ydcG - - S - - - EVE domain
IGBBEFOO_00334 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGBBEFOO_00335 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
IGBBEFOO_00336 1.93e-110 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
IGBBEFOO_00344 4.41e-270 ydcL - - L - - - Belongs to the 'phage' integrase family
IGBBEFOO_00345 1.41e-119 - - - E - - - IrrE N-terminal-like domain
IGBBEFOO_00346 1.91e-81 - - - K - - - Transcriptional
IGBBEFOO_00347 8.96e-24 - - - - - - - -
IGBBEFOO_00348 9.52e-56 - - - - - - - -
IGBBEFOO_00350 1.84e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
IGBBEFOO_00351 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
IGBBEFOO_00352 2.62e-263 nicK - - L ko:K07467 - ko00000 Replication initiation factor
IGBBEFOO_00355 1.38e-43 yddA - - - - - - -
IGBBEFOO_00356 7.65e-232 yddB - - S - - - Conjugative transposon protein TcpC
IGBBEFOO_00357 3.41e-54 yddC - - - - - - -
IGBBEFOO_00358 7.8e-124 yddD - - S - - - TcpE family
IGBBEFOO_00359 0.0 yddE - - S - - - AAA-like domain
IGBBEFOO_00360 2.81e-74 - - - S - - - Domain of unknown function (DUF1874)
IGBBEFOO_00361 0.0 yddG - - S - - - maturation of SSU-rRNA
IGBBEFOO_00362 4.74e-243 yddH - - M - - - Lysozyme-like
IGBBEFOO_00363 4.05e-114 yddI - - - - - - -
IGBBEFOO_00364 6.67e-86 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
IGBBEFOO_00365 8.08e-192 - - - S - - - TIR domain
IGBBEFOO_00366 5.17e-92 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IGBBEFOO_00368 2.93e-212 - - - - - - - -
IGBBEFOO_00369 2.43e-241 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IGBBEFOO_00370 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
IGBBEFOO_00371 2.17e-102 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
IGBBEFOO_00372 1.62e-128 yddQ - - Q - - - Isochorismatase family
IGBBEFOO_00373 1.34e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
IGBBEFOO_00374 3.35e-288 ydeG3 - - EGP - - - Major Facilitator Superfamily
IGBBEFOO_00379 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
IGBBEFOO_00380 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
IGBBEFOO_00381 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
IGBBEFOO_00382 2.47e-47 ydzE - - EG - - - spore germination
IGBBEFOO_00383 3.23e-215 - - - K - - - AraC-like ligand binding domain
IGBBEFOO_00384 4.99e-224 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IGBBEFOO_00385 2.87e-213 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
IGBBEFOO_00386 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IGBBEFOO_00387 1.19e-280 ydeG - - EGP - - - Major facilitator superfamily
IGBBEFOO_00388 4.76e-72 ydeH - - - - - - -
IGBBEFOO_00389 1.26e-138 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
IGBBEFOO_00390 6.11e-150 - - - - - - - -
IGBBEFOO_00391 4.66e-197 ydeK - - EG - - - -transporter
IGBBEFOO_00392 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IGBBEFOO_00393 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
IGBBEFOO_00394 8.6e-138 - - - S ko:K07002 - ko00000 Serine hydrolase
IGBBEFOO_00395 1.33e-77 - - - K - - - HxlR-like helix-turn-helix
IGBBEFOO_00396 1.68e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IGBBEFOO_00397 5.03e-91 ydeP - - K - - - Transcriptional regulator
IGBBEFOO_00398 2.44e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
IGBBEFOO_00399 1.51e-261 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
IGBBEFOO_00400 3.74e-136 ydeS - - K - - - Transcriptional regulator
IGBBEFOO_00401 2.56e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
IGBBEFOO_00402 9.07e-297 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IGBBEFOO_00403 8.05e-191 - - - J - - - GNAT acetyltransferase
IGBBEFOO_00404 3.05e-207 - - - EG - - - EamA-like transporter family
IGBBEFOO_00405 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IGBBEFOO_00406 5.97e-151 ydfE - - S - - - Flavin reductase like domain
IGBBEFOO_00407 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IGBBEFOO_00408 1.37e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IGBBEFOO_00410 4.11e-253 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_00411 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IGBBEFOO_00412 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
IGBBEFOO_00413 9.73e-226 - - - S - - - Alpha/beta hydrolase family
IGBBEFOO_00414 6.79e-152 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
IGBBEFOO_00415 2.13e-189 - - - K - - - Bacterial transcription activator, effector binding domain
IGBBEFOO_00416 3.15e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IGBBEFOO_00417 3.45e-145 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
IGBBEFOO_00418 9.49e-239 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IGBBEFOO_00419 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
IGBBEFOO_00420 9.63e-77 ydfQ - - CO - - - Thioredoxin
IGBBEFOO_00421 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
IGBBEFOO_00422 5.33e-39 - - - - - - - -
IGBBEFOO_00424 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
IGBBEFOO_00425 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
IGBBEFOO_00426 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IGBBEFOO_00427 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
IGBBEFOO_00428 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
IGBBEFOO_00429 7.86e-132 ydgC - - K - - - Bacterial regulatory proteins, tetR family
IGBBEFOO_00430 4.21e-72 - - - S - - - DoxX-like family
IGBBEFOO_00431 2.49e-114 yycN - - K - - - Acetyltransferase
IGBBEFOO_00432 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
IGBBEFOO_00433 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IGBBEFOO_00434 5.09e-119 - - - S - - - DinB family
IGBBEFOO_00435 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGBBEFOO_00436 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
IGBBEFOO_00437 6.42e-147 ydgI - - C - - - nitroreductase
IGBBEFOO_00438 1.15e-90 - - - K - - - Winged helix DNA-binding domain
IGBBEFOO_00439 5.97e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IGBBEFOO_00440 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
IGBBEFOO_00441 5.24e-158 ydhC - - K - - - FCD
IGBBEFOO_00442 8.92e-310 ydhD - - M - - - Glycosyl hydrolase
IGBBEFOO_00443 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IGBBEFOO_00444 7.71e-166 - - - - - - - -
IGBBEFOO_00445 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IGBBEFOO_00446 9.93e-91 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IGBBEFOO_00448 1.43e-112 - - - K - - - Acetyltransferase (GNAT) domain
IGBBEFOO_00449 1.25e-236 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IGBBEFOO_00450 4.01e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
IGBBEFOO_00451 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
IGBBEFOO_00452 7.97e-65 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_00453 6.09e-70 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_00454 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGBBEFOO_00455 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IGBBEFOO_00456 1.9e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
IGBBEFOO_00457 9.28e-219 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
IGBBEFOO_00458 1.93e-244 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IGBBEFOO_00459 3.49e-273 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
IGBBEFOO_00460 1.12e-98 ydhU - - P ko:K07217 - ko00000 Catalase
IGBBEFOO_00461 7.94e-22 ydhU - - P ko:K07217 - ko00000 Manganese containing catalase
IGBBEFOO_00464 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IGBBEFOO_00467 3.06e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IGBBEFOO_00468 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
IGBBEFOO_00469 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
IGBBEFOO_00470 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IGBBEFOO_00471 1.63e-241 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IGBBEFOO_00472 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
IGBBEFOO_00473 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IGBBEFOO_00474 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IGBBEFOO_00475 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IGBBEFOO_00476 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IGBBEFOO_00477 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
IGBBEFOO_00478 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
IGBBEFOO_00479 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IGBBEFOO_00480 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IGBBEFOO_00482 6.93e-88 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
IGBBEFOO_00483 0.0 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
IGBBEFOO_00484 1.43e-297 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
IGBBEFOO_00486 3.67e-254 - - - V - - - AAA domain (dynein-related subfamily)
IGBBEFOO_00487 0.0 - - - J - - - LlaJI restriction endonuclease
IGBBEFOO_00488 3.73e-11 ydjC - - S - - - Abhydrolase domain containing 18
IGBBEFOO_00489 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IGBBEFOO_00490 1.06e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
IGBBEFOO_00491 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
IGBBEFOO_00492 5.39e-224 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IGBBEFOO_00493 5.36e-148 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
IGBBEFOO_00494 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IGBBEFOO_00495 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
IGBBEFOO_00496 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
IGBBEFOO_00497 1.37e-248 - - - S - - - Ion transport 2 domain protein
IGBBEFOO_00498 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IGBBEFOO_00499 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
IGBBEFOO_00500 1.79e-84 ydjM - - M - - - Lytic transglycolase
IGBBEFOO_00501 3.76e-213 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
IGBBEFOO_00503 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
IGBBEFOO_00504 3.21e-205 - - - I - - - Alpha/beta hydrolase family
IGBBEFOO_00505 1.9e-233 yeaA - - S - - - Protein of unknown function (DUF4003)
IGBBEFOO_00506 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
IGBBEFOO_00507 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IGBBEFOO_00508 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IGBBEFOO_00509 1.18e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
IGBBEFOO_00510 6.74e-287 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IGBBEFOO_00511 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
IGBBEFOO_00512 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IGBBEFOO_00513 1.2e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IGBBEFOO_00514 1.44e-165 yebC - - M - - - Membrane
IGBBEFOO_00516 2.66e-120 yebE - - S - - - UPF0316 protein
IGBBEFOO_00517 3.13e-38 yebG - - S - - - NETI protein
IGBBEFOO_00518 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IGBBEFOO_00519 9.39e-278 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IGBBEFOO_00520 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IGBBEFOO_00521 1.06e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IGBBEFOO_00522 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGBBEFOO_00523 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGBBEFOO_00524 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGBBEFOO_00525 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IGBBEFOO_00526 4.2e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IGBBEFOO_00527 4.4e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IGBBEFOO_00528 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IGBBEFOO_00529 2.07e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IGBBEFOO_00530 5.26e-96 - - - K - - - helix_turn_helix ASNC type
IGBBEFOO_00531 1.91e-297 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
IGBBEFOO_00532 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
IGBBEFOO_00533 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
IGBBEFOO_00534 7.03e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
IGBBEFOO_00535 7.62e-68 yerC - - S - - - protein conserved in bacteria
IGBBEFOO_00536 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
IGBBEFOO_00538 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IGBBEFOO_00539 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IGBBEFOO_00540 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IGBBEFOO_00541 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
IGBBEFOO_00542 6.28e-253 yerI - - S - - - homoserine kinase type II (protein kinase fold)
IGBBEFOO_00543 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IGBBEFOO_00544 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IGBBEFOO_00545 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGBBEFOO_00546 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IGBBEFOO_00547 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGBBEFOO_00548 2.93e-201 yerO - - K - - - Transcriptional regulator
IGBBEFOO_00549 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IGBBEFOO_00550 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IGBBEFOO_00551 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGBBEFOO_00552 3.63e-127 - - - L - - - Recombinase
IGBBEFOO_00553 5.61e-71 - - - L - - - Resolvase, N terminal domain
IGBBEFOO_00554 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
IGBBEFOO_00555 0.0 - - - L - - - DEAD-like helicases superfamily
IGBBEFOO_00556 1.37e-271 yeeC - - P - - - T5orf172
IGBBEFOO_00557 7.48e-05 - - - - - - - -
IGBBEFOO_00558 4.15e-42 - - - S - - - Colicin immunity protein / pyocin immunity protein
IGBBEFOO_00559 2.1e-109 - - - S - - - Protein of unknown function, DUF600
IGBBEFOO_00560 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
IGBBEFOO_00561 1.73e-246 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
IGBBEFOO_00562 1.33e-275 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
IGBBEFOO_00564 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
IGBBEFOO_00566 1.86e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_00567 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
IGBBEFOO_00568 8.81e-206 yesF - - GM - - - NAD(P)H-binding
IGBBEFOO_00569 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
IGBBEFOO_00570 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
IGBBEFOO_00571 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
IGBBEFOO_00572 1.76e-132 yesJ - - K - - - Acetyltransferase (GNAT) family
IGBBEFOO_00574 3.52e-135 yesL - - S - - - Protein of unknown function, DUF624
IGBBEFOO_00575 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_00576 5.07e-260 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
IGBBEFOO_00577 8.76e-316 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IGBBEFOO_00578 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGBBEFOO_00579 1.31e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGBBEFOO_00580 6.85e-255 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
IGBBEFOO_00581 0.0 yesS - - K - - - Transcriptional regulator
IGBBEFOO_00582 3.56e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
IGBBEFOO_00583 1.41e-169 yesU - - S - - - Domain of unknown function (DUF1961)
IGBBEFOO_00584 3.44e-146 - - - S - - - Protein of unknown function, DUF624
IGBBEFOO_00585 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
IGBBEFOO_00586 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
IGBBEFOO_00587 9.13e-160 - - - E - - - GDSL-like Lipase/Acylhydrolase
IGBBEFOO_00588 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
IGBBEFOO_00589 0.0 yetA - - - - - - -
IGBBEFOO_00590 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IGBBEFOO_00591 2.9e-227 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
IGBBEFOO_00592 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGBBEFOO_00593 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IGBBEFOO_00594 3.13e-158 yetF - - S - - - membrane
IGBBEFOO_00595 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
IGBBEFOO_00596 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGBBEFOO_00597 9.79e-45 - - - - - - - -
IGBBEFOO_00598 3.87e-114 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IGBBEFOO_00599 1.97e-54 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IGBBEFOO_00600 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
IGBBEFOO_00601 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
IGBBEFOO_00602 7.35e-203 - - - EG - - - EamA-like transporter family
IGBBEFOO_00603 6.74e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGBBEFOO_00604 4.77e-270 yetM - - CH - - - FAD binding domain
IGBBEFOO_00605 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
IGBBEFOO_00606 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IGBBEFOO_00607 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IGBBEFOO_00608 2.15e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
IGBBEFOO_00609 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
IGBBEFOO_00610 9.79e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
IGBBEFOO_00611 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
IGBBEFOO_00612 2.84e-244 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
IGBBEFOO_00613 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_00614 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IGBBEFOO_00615 4.16e-313 yfnA - - E ko:K03294 - ko00000 amino acid
IGBBEFOO_00616 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IGBBEFOO_00617 5.14e-161 yfmS - - NT - - - chemotaxis protein
IGBBEFOO_00618 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IGBBEFOO_00619 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
IGBBEFOO_00620 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
IGBBEFOO_00621 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
IGBBEFOO_00622 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IGBBEFOO_00623 1.86e-266 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
IGBBEFOO_00624 1.86e-107 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
IGBBEFOO_00625 4.21e-242 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
IGBBEFOO_00626 1.72e-268 - - - G - - - Major Facilitator Superfamily
IGBBEFOO_00627 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
IGBBEFOO_00628 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IGBBEFOO_00629 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_00630 2.85e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_00631 2.88e-221 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IGBBEFOO_00632 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
IGBBEFOO_00633 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
IGBBEFOO_00634 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IGBBEFOO_00635 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IGBBEFOO_00636 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IGBBEFOO_00637 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IGBBEFOO_00638 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
IGBBEFOO_00640 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IGBBEFOO_00641 7.21e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IGBBEFOO_00642 1.43e-277 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IGBBEFOO_00643 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IGBBEFOO_00644 2.51e-159 yflK - - S - - - protein conserved in bacteria
IGBBEFOO_00645 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
IGBBEFOO_00646 6.9e-27 yflI - - - - - - -
IGBBEFOO_00647 3.63e-66 yflH - - S - - - Protein of unknown function (DUF3243)
IGBBEFOO_00648 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IGBBEFOO_00649 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IGBBEFOO_00650 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IGBBEFOO_00651 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
IGBBEFOO_00652 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
IGBBEFOO_00653 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
IGBBEFOO_00655 2.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
IGBBEFOO_00656 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
IGBBEFOO_00657 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_00658 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
IGBBEFOO_00659 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
IGBBEFOO_00660 5.27e-161 frp - - C - - - nitroreductase
IGBBEFOO_00661 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IGBBEFOO_00662 8.44e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IGBBEFOO_00663 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_00664 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
IGBBEFOO_00665 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IGBBEFOO_00666 2.53e-67 yfkI - - S - - - gas vesicle protein
IGBBEFOO_00667 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IGBBEFOO_00668 1.64e-12 - - - - - - - -
IGBBEFOO_00669 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_00670 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
IGBBEFOO_00671 3.69e-189 yfkD - - S - - - YfkD-like protein
IGBBEFOO_00672 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
IGBBEFOO_00673 1.76e-283 yfkA - - S - - - YfkB-like domain
IGBBEFOO_00674 3.26e-36 yfjT - - - - - - -
IGBBEFOO_00675 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
IGBBEFOO_00676 4.82e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IGBBEFOO_00677 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
IGBBEFOO_00678 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IGBBEFOO_00679 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGBBEFOO_00680 3e-53 - - - S - - - YfzA-like protein
IGBBEFOO_00681 1.21e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGBBEFOO_00682 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
IGBBEFOO_00684 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IGBBEFOO_00685 2.75e-244 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IGBBEFOO_00686 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IGBBEFOO_00687 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IGBBEFOO_00688 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
IGBBEFOO_00689 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
IGBBEFOO_00690 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
IGBBEFOO_00691 1.53e-104 - - - S - - - Family of unknown function (DUF5381)
IGBBEFOO_00692 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
IGBBEFOO_00693 2.5e-185 yfjC - - - - - - -
IGBBEFOO_00694 1.94e-270 yfjB - - - - - - -
IGBBEFOO_00695 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
IGBBEFOO_00696 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IGBBEFOO_00697 7.45e-182 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
IGBBEFOO_00698 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_00699 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
IGBBEFOO_00700 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IGBBEFOO_00701 2.01e-84 yfiD3 - - S - - - DoxX
IGBBEFOO_00702 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
IGBBEFOO_00703 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
IGBBEFOO_00704 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IGBBEFOO_00705 5.47e-234 - - - G - - - Xylose isomerase
IGBBEFOO_00706 5.17e-295 - - - S - - - Oxidoreductase
IGBBEFOO_00708 7.54e-276 baeS - - T - - - Histidine kinase
IGBBEFOO_00709 1.05e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
IGBBEFOO_00710 3.35e-218 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_00711 3.66e-274 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IGBBEFOO_00712 4.56e-267 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IGBBEFOO_00713 1.89e-128 padR - - K - - - transcriptional
IGBBEFOO_00714 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IGBBEFOO_00715 2.29e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IGBBEFOO_00716 4.18e-141 yfiR - - K - - - Transcriptional regulator
IGBBEFOO_00717 4.51e-281 yfiS - - EGP - - - Major facilitator superfamily
IGBBEFOO_00718 2.41e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
IGBBEFOO_00719 0.0 yfiU - - EGP - - - the major facilitator superfamily
IGBBEFOO_00720 5.39e-106 yfiV - - K - - - transcriptional
IGBBEFOO_00721 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IGBBEFOO_00722 2.81e-233 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IGBBEFOO_00723 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_00724 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_00725 7.61e-215 yfhB - - S - - - PhzF family
IGBBEFOO_00726 2.87e-138 yfhC - - C - - - nitroreductase
IGBBEFOO_00727 8.86e-35 yfhD - - S - - - YfhD-like protein
IGBBEFOO_00729 1.13e-221 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
IGBBEFOO_00730 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
IGBBEFOO_00731 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
IGBBEFOO_00733 2.45e-268 yfhI - - EGP - - - -transporter
IGBBEFOO_00734 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
IGBBEFOO_00735 8.95e-60 yfhJ - - S - - - WVELL protein
IGBBEFOO_00736 3.58e-119 yfhK - - T - - - Bacterial SH3 domain homologues
IGBBEFOO_00737 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
IGBBEFOO_00738 3.37e-219 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
IGBBEFOO_00739 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IGBBEFOO_00740 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
IGBBEFOO_00741 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
IGBBEFOO_00742 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
IGBBEFOO_00743 1.73e-48 yfhS - - - - - - -
IGBBEFOO_00744 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_00745 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
IGBBEFOO_00746 2.01e-49 ygaB - - S - - - YgaB-like protein
IGBBEFOO_00747 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IGBBEFOO_00748 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
IGBBEFOO_00749 1.87e-238 ygaE - - S - - - Membrane
IGBBEFOO_00750 1.19e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IGBBEFOO_00751 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
IGBBEFOO_00752 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IGBBEFOO_00753 4.67e-75 ygzB - - S - - - UPF0295 protein
IGBBEFOO_00754 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
IGBBEFOO_00755 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IGBBEFOO_00772 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
IGBBEFOO_00773 3.88e-37 - - - - - - - -
IGBBEFOO_00774 6.95e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
IGBBEFOO_00775 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IGBBEFOO_00776 0.0 ygaK - - C - - - Berberine and berberine like
IGBBEFOO_00778 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IGBBEFOO_00779 4.15e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IGBBEFOO_00780 1.78e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
IGBBEFOO_00781 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IGBBEFOO_00782 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
IGBBEFOO_00784 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGBBEFOO_00785 2.79e-102 ygaO - - - - - - -
IGBBEFOO_00786 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_00788 1.92e-147 yhzB - - S - - - B3/4 domain
IGBBEFOO_00789 5.09e-285 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IGBBEFOO_00790 4.79e-226 yhbB - - S - - - Putative amidase domain
IGBBEFOO_00791 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IGBBEFOO_00792 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
IGBBEFOO_00793 2.29e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IGBBEFOO_00794 4.08e-110 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IGBBEFOO_00795 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
IGBBEFOO_00796 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
IGBBEFOO_00797 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
IGBBEFOO_00798 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
IGBBEFOO_00799 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
IGBBEFOO_00800 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
IGBBEFOO_00801 3.95e-59 yhcC - - - - - - -
IGBBEFOO_00802 2.92e-69 - - - - - - - -
IGBBEFOO_00803 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_00804 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_00805 6.47e-213 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_00806 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IGBBEFOO_00807 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IGBBEFOO_00808 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IGBBEFOO_00809 2.47e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
IGBBEFOO_00810 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IGBBEFOO_00811 3.23e-80 yhcM - - - - - - -
IGBBEFOO_00812 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IGBBEFOO_00813 3.96e-227 yhcP - - - - - - -
IGBBEFOO_00814 1.68e-146 yhcQ - - M - - - Spore coat protein
IGBBEFOO_00815 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IGBBEFOO_00816 3.9e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
IGBBEFOO_00817 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IGBBEFOO_00818 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
IGBBEFOO_00819 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
IGBBEFOO_00820 3.04e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
IGBBEFOO_00821 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IGBBEFOO_00822 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IGBBEFOO_00823 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IGBBEFOO_00824 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IGBBEFOO_00825 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IGBBEFOO_00826 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IGBBEFOO_00827 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
IGBBEFOO_00828 2.29e-273 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_00829 5.68e-148 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IGBBEFOO_00830 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
IGBBEFOO_00831 1.65e-51 yhdB - - S - - - YhdB-like protein
IGBBEFOO_00832 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
IGBBEFOO_00833 2.4e-275 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IGBBEFOO_00834 1.37e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
IGBBEFOO_00835 5.29e-307 ygxB - - M - - - Conserved TM helix
IGBBEFOO_00836 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
IGBBEFOO_00837 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IGBBEFOO_00838 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IGBBEFOO_00839 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_00840 5.51e-263 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IGBBEFOO_00841 1.41e-208 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_00842 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
IGBBEFOO_00843 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IGBBEFOO_00844 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IGBBEFOO_00845 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IGBBEFOO_00846 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
IGBBEFOO_00847 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
IGBBEFOO_00848 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IGBBEFOO_00849 6.74e-244 yhdN - - C - - - Aldo keto reductase
IGBBEFOO_00850 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IGBBEFOO_00851 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IGBBEFOO_00852 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
IGBBEFOO_00853 4.37e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IGBBEFOO_00854 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
IGBBEFOO_00855 2.69e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IGBBEFOO_00856 1.01e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IGBBEFOO_00857 5.44e-174 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IGBBEFOO_00858 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
IGBBEFOO_00859 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
IGBBEFOO_00860 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IGBBEFOO_00861 5.7e-200 nodB1 - - G - - - deacetylase
IGBBEFOO_00862 2.23e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IGBBEFOO_00863 3.94e-307 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IGBBEFOO_00864 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
IGBBEFOO_00865 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IGBBEFOO_00866 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IGBBEFOO_00867 3.31e-143 yheG - - GM - - - NAD(P)H-binding
IGBBEFOO_00868 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IGBBEFOO_00869 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
IGBBEFOO_00870 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
IGBBEFOO_00871 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
IGBBEFOO_00872 1.51e-261 yheB - - S - - - Belongs to the UPF0754 family
IGBBEFOO_00873 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
IGBBEFOO_00874 6.69e-264 yhaZ - - L - - - DNA alkylation repair enzyme
IGBBEFOO_00875 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
IGBBEFOO_00876 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
IGBBEFOO_00877 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
IGBBEFOO_00878 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IGBBEFOO_00880 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
IGBBEFOO_00881 2.29e-36 - - - S - - - YhzD-like protein
IGBBEFOO_00882 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_00883 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
IGBBEFOO_00884 9.85e-303 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
IGBBEFOO_00885 0.0 yhaN - - L - - - AAA domain
IGBBEFOO_00886 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
IGBBEFOO_00887 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
IGBBEFOO_00888 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IGBBEFOO_00889 1.4e-116 yhaK - - S - - - Putative zincin peptidase
IGBBEFOO_00890 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
IGBBEFOO_00891 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
IGBBEFOO_00892 1.74e-54 yhaH - - S - - - YtxH-like protein
IGBBEFOO_00893 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
IGBBEFOO_00894 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IGBBEFOO_00895 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IGBBEFOO_00896 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
IGBBEFOO_00897 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IGBBEFOO_00898 5e-162 ecsC - - S - - - EcsC protein family
IGBBEFOO_00899 4.8e-295 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IGBBEFOO_00900 8.98e-317 yhfA - - C - - - membrane
IGBBEFOO_00901 1.33e-23 - - - C - - - Rubrerythrin
IGBBEFOO_00902 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
IGBBEFOO_00903 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IGBBEFOO_00904 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IGBBEFOO_00905 2.06e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IGBBEFOO_00906 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IGBBEFOO_00907 3.49e-133 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_00908 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
IGBBEFOO_00909 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IGBBEFOO_00910 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
IGBBEFOO_00911 2.68e-253 yhfE - - G - - - peptidase M42
IGBBEFOO_00912 3.75e-94 - - - S - - - ASCH
IGBBEFOO_00913 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IGBBEFOO_00914 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IGBBEFOO_00915 1.21e-246 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IGBBEFOO_00916 1.82e-144 yhfK - - GM - - - NmrA-like family
IGBBEFOO_00917 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IGBBEFOO_00918 2.78e-85 yhfM - - - - - - -
IGBBEFOO_00919 9.64e-308 yhfN - - O - - - Peptidase M48
IGBBEFOO_00920 2.94e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IGBBEFOO_00921 2.75e-105 - - - K - - - acetyltransferase
IGBBEFOO_00922 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
IGBBEFOO_00923 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IGBBEFOO_00924 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
IGBBEFOO_00925 1.19e-256 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IGBBEFOO_00926 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IGBBEFOO_00927 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IGBBEFOO_00928 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
IGBBEFOO_00929 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IGBBEFOO_00930 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_00931 9.84e-45 yhzC - - S - - - IDEAL
IGBBEFOO_00932 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
IGBBEFOO_00933 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IGBBEFOO_00934 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
IGBBEFOO_00935 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IGBBEFOO_00936 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
IGBBEFOO_00937 2.57e-78 yhjD - - - - - - -
IGBBEFOO_00938 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
IGBBEFOO_00939 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IGBBEFOO_00940 0.0 yhjG - - CH - - - FAD binding domain
IGBBEFOO_00941 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGBBEFOO_00942 3.12e-273 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
IGBBEFOO_00943 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IGBBEFOO_00944 2.63e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
IGBBEFOO_00945 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IGBBEFOO_00946 2.63e-240 yhjM - - K - - - Transcriptional regulator
IGBBEFOO_00947 2.14e-260 yhjN - - S ko:K07120 - ko00000 membrane
IGBBEFOO_00948 1.27e-272 - - - EGP - - - Transmembrane secretion effector
IGBBEFOO_00949 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
IGBBEFOO_00950 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
IGBBEFOO_00951 9.3e-102 yhjR - - S - - - Rubrerythrin
IGBBEFOO_00952 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
IGBBEFOO_00953 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IGBBEFOO_00954 1.2e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IGBBEFOO_00955 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
IGBBEFOO_00956 1.34e-66 yisB - - V - - - COG1403 Restriction endonuclease
IGBBEFOO_00957 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
IGBBEFOO_00958 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
IGBBEFOO_00959 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
IGBBEFOO_00960 8.23e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
IGBBEFOO_00961 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
IGBBEFOO_00962 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
IGBBEFOO_00963 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
IGBBEFOO_00964 3.96e-224 cotH - - M ko:K06330 - ko00000 Spore Coat
IGBBEFOO_00965 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IGBBEFOO_00966 1.02e-74 yisL - - S - - - UPF0344 protein
IGBBEFOO_00967 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IGBBEFOO_00968 7.48e-137 yisN - - S - - - Protein of unknown function (DUF2777)
IGBBEFOO_00969 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IGBBEFOO_00970 1.85e-115 yizA - - S - - - Damage-inducible protein DinB
IGBBEFOO_00971 6.82e-193 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
IGBBEFOO_00972 1.01e-310 yisQ - - V - - - Mate efflux family protein
IGBBEFOO_00973 1.41e-207 yisR - - K - - - Transcriptional regulator
IGBBEFOO_00974 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IGBBEFOO_00975 9.72e-254 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IGBBEFOO_00976 7.28e-122 yisT - - S - - - DinB family
IGBBEFOO_00977 5.42e-140 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
IGBBEFOO_00978 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IGBBEFOO_00979 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
IGBBEFOO_00980 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IGBBEFOO_00981 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IGBBEFOO_00982 1.37e-295 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IGBBEFOO_00983 9.51e-185 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IGBBEFOO_00984 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
IGBBEFOO_00985 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
IGBBEFOO_00986 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IGBBEFOO_00987 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IGBBEFOO_00988 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_00989 7.86e-207 yitH - - K - - - Acetyltransferase (GNAT) domain
IGBBEFOO_00990 8.19e-107 - - - S - - - Acetyltransferase (GNAT) domain
IGBBEFOO_00991 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IGBBEFOO_00992 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
IGBBEFOO_00993 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
IGBBEFOO_00994 4.16e-122 - - - - - - - -
IGBBEFOO_00995 1.42e-218 - - - - - - - -
IGBBEFOO_00996 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
IGBBEFOO_00997 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
IGBBEFOO_00998 7.76e-123 - - - - - - - -
IGBBEFOO_00999 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
IGBBEFOO_01000 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IGBBEFOO_01001 1.1e-197 yitS - - S - - - protein conserved in bacteria
IGBBEFOO_01002 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IGBBEFOO_01003 1.61e-92 ipi - - S - - - Intracellular proteinase inhibitor
IGBBEFOO_01004 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
IGBBEFOO_01005 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IGBBEFOO_01006 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IGBBEFOO_01007 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
IGBBEFOO_01008 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
IGBBEFOO_01009 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
IGBBEFOO_01010 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
IGBBEFOO_01011 9.02e-256 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IGBBEFOO_01012 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IGBBEFOO_01013 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IGBBEFOO_01014 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
IGBBEFOO_01015 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IGBBEFOO_01016 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
IGBBEFOO_01017 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IGBBEFOO_01018 2.51e-39 yjzC - - S - - - YjzC-like protein
IGBBEFOO_01019 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
IGBBEFOO_01020 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
IGBBEFOO_01021 5.41e-134 yjaV - - - - - - -
IGBBEFOO_01022 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
IGBBEFOO_01023 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
IGBBEFOO_01024 2.67e-38 yjzB - - - - - - -
IGBBEFOO_01025 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IGBBEFOO_01026 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IGBBEFOO_01027 9.48e-193 yjaZ - - O - - - Zn-dependent protease
IGBBEFOO_01028 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGBBEFOO_01029 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGBBEFOO_01030 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
IGBBEFOO_01031 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGBBEFOO_01032 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGBBEFOO_01033 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
IGBBEFOO_01034 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
IGBBEFOO_01035 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IGBBEFOO_01036 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGBBEFOO_01037 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGBBEFOO_01038 1.37e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGBBEFOO_01039 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGBBEFOO_01040 3.98e-248 yjbB - - EGP - - - Major Facilitator Superfamily
IGBBEFOO_01041 2.65e-133 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IGBBEFOO_01042 3.51e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IGBBEFOO_01043 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
IGBBEFOO_01044 6.89e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IGBBEFOO_01045 1.31e-283 coiA - - S ko:K06198 - ko00000 Competence protein
IGBBEFOO_01046 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IGBBEFOO_01047 2.68e-28 - - - - - - - -
IGBBEFOO_01049 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IGBBEFOO_01050 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
IGBBEFOO_01051 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IGBBEFOO_01052 5.15e-130 yjbK - - S - - - protein conserved in bacteria
IGBBEFOO_01053 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
IGBBEFOO_01054 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
IGBBEFOO_01055 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IGBBEFOO_01056 9.4e-206 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IGBBEFOO_01057 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IGBBEFOO_01058 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IGBBEFOO_01059 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IGBBEFOO_01060 4.01e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
IGBBEFOO_01061 1.14e-277 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
IGBBEFOO_01062 5.35e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
IGBBEFOO_01063 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IGBBEFOO_01064 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IGBBEFOO_01065 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IGBBEFOO_01066 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
IGBBEFOO_01067 2.32e-107 yjbX - - S - - - Spore coat protein
IGBBEFOO_01068 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
IGBBEFOO_01069 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
IGBBEFOO_01070 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
IGBBEFOO_01071 1.08e-54 cotW - - - ko:K06341 - ko00000 -
IGBBEFOO_01072 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
IGBBEFOO_01073 3.03e-76 yjcA - - S - - - Protein of unknown function (DUF1360)
IGBBEFOO_01076 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
IGBBEFOO_01077 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IGBBEFOO_01078 6.31e-51 - - - - - - - -
IGBBEFOO_01079 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IGBBEFOO_01080 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
IGBBEFOO_01081 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
IGBBEFOO_01082 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IGBBEFOO_01083 6.4e-281 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IGBBEFOO_01084 2.13e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
IGBBEFOO_01085 2.58e-274 yjcL - - S - - - Protein of unknown function (DUF819)
IGBBEFOO_01088 3.75e-269 - - - S - - - Putative amidase domain
IGBBEFOO_01089 1.52e-68 yjcN - - - - - - -
IGBBEFOO_01092 2.24e-106 - - - L - - - Transposase
IGBBEFOO_01093 5.68e-100 yjcP - - - - - - -
IGBBEFOO_01094 1.01e-65 - - - S - - - YjcQ protein
IGBBEFOO_01095 3.29e-121 yqaS - - L - - - DNA packaging
IGBBEFOO_01096 3.8e-63 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
IGBBEFOO_01097 3.42e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
IGBBEFOO_01098 0.000759 - - - - - - - -
IGBBEFOO_01099 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
IGBBEFOO_01100 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_01101 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IGBBEFOO_01102 4.79e-78 yjdF3 - - S - - - Protein of unknown function (DUF2992)
IGBBEFOO_01103 1.36e-121 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IGBBEFOO_01105 1.01e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IGBBEFOO_01106 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
IGBBEFOO_01107 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
IGBBEFOO_01108 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IGBBEFOO_01110 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IGBBEFOO_01111 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
IGBBEFOO_01112 1.95e-30 yjfB - - S - - - Putative motility protein
IGBBEFOO_01113 3.24e-219 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
IGBBEFOO_01114 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
IGBBEFOO_01115 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
IGBBEFOO_01116 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
IGBBEFOO_01117 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
IGBBEFOO_01119 1.91e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IGBBEFOO_01121 1.48e-289 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IGBBEFOO_01122 8.74e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IGBBEFOO_01123 1.11e-41 - - - - - - - -
IGBBEFOO_01124 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IGBBEFOO_01125 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
IGBBEFOO_01126 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IGBBEFOO_01127 1.09e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
IGBBEFOO_01128 8.91e-121 yjlB - - S - - - Cupin domain
IGBBEFOO_01129 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
IGBBEFOO_01130 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IGBBEFOO_01131 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
IGBBEFOO_01132 6.34e-316 - - - G ko:K03292 - ko00000 symporter YjmB
IGBBEFOO_01133 2.02e-248 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
IGBBEFOO_01134 1.6e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IGBBEFOO_01135 1.66e-274 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
IGBBEFOO_01136 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_01137 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
IGBBEFOO_01138 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
IGBBEFOO_01139 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
IGBBEFOO_01140 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IGBBEFOO_01141 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
IGBBEFOO_01142 4.87e-106 yjoA - - S - - - DinB family
IGBBEFOO_01143 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
IGBBEFOO_01144 1.6e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IGBBEFOO_01146 1.79e-55 - - - S - - - YCII-related domain
IGBBEFOO_01147 1.37e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IGBBEFOO_01148 3.31e-81 yjqA - - S - - - Bacterial PH domain
IGBBEFOO_01149 1.47e-143 yjqB - - S - - - Pfam:DUF867
IGBBEFOO_01150 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
IGBBEFOO_01151 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
IGBBEFOO_01152 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
IGBBEFOO_01154 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
IGBBEFOO_01155 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
IGBBEFOO_01159 5.95e-112 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IGBBEFOO_01160 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
IGBBEFOO_01161 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
IGBBEFOO_01162 0.0 yqbA - - S - - - portal protein
IGBBEFOO_01163 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
IGBBEFOO_01164 3.91e-217 xkdG - - S - - - Phage capsid family
IGBBEFOO_01165 2.06e-85 yqbG - - S - - - Protein of unknown function (DUF3199)
IGBBEFOO_01166 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
IGBBEFOO_01167 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
IGBBEFOO_01168 2.87e-101 xkdJ - - - - - - -
IGBBEFOO_01169 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
IGBBEFOO_01170 6.01e-99 xkdM - - S - - - Phage tail tube protein
IGBBEFOO_01171 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IGBBEFOO_01172 0.0 xkdO - - L - - - Transglycosylase SLT domain
IGBBEFOO_01173 1.77e-158 xkdP - - S - - - Lysin motif
IGBBEFOO_01174 2.31e-232 xkdQ - - G - - - NLP P60 protein
IGBBEFOO_01175 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
IGBBEFOO_01176 1.97e-92 xkdS - - S - - - Protein of unknown function (DUF2634)
IGBBEFOO_01177 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IGBBEFOO_01178 9.63e-136 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IGBBEFOO_01179 4.43e-56 - - - - - - - -
IGBBEFOO_01180 0.0 - - - - - - - -
IGBBEFOO_01181 8.68e-74 xkdW - - S - - - XkdW protein
IGBBEFOO_01182 9.34e-33 xkdX - - - - - - -
IGBBEFOO_01183 1.51e-198 xepA - - - - - - -
IGBBEFOO_01184 7.71e-52 xhlA - - S - - - Haemolysin XhlA
IGBBEFOO_01185 8.12e-53 xhlB - - S - - - SPP1 phage holin
IGBBEFOO_01186 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IGBBEFOO_01187 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
IGBBEFOO_01188 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
IGBBEFOO_01189 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
IGBBEFOO_01190 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
IGBBEFOO_01191 7.7e-311 steT - - E ko:K03294 - ko00000 amino acid
IGBBEFOO_01192 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IGBBEFOO_01194 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IGBBEFOO_01195 1.34e-230 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IGBBEFOO_01197 6.72e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IGBBEFOO_01198 1.54e-183 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
IGBBEFOO_01199 2.42e-197 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
IGBBEFOO_01200 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGBBEFOO_01201 6.35e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGBBEFOO_01202 6.22e-242 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGBBEFOO_01203 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IGBBEFOO_01205 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
IGBBEFOO_01206 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IGBBEFOO_01207 2.56e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IGBBEFOO_01208 1.77e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGBBEFOO_01209 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
IGBBEFOO_01210 4.37e-206 ykgA - - E - - - Amidinotransferase
IGBBEFOO_01211 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
IGBBEFOO_01212 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IGBBEFOO_01213 5.85e-13 - - - - - - - -
IGBBEFOO_01214 4.81e-168 ykjA - - S - - - Protein of unknown function (DUF421)
IGBBEFOO_01215 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
IGBBEFOO_01216 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IGBBEFOO_01217 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
IGBBEFOO_01218 2.86e-68 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
IGBBEFOO_01219 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IGBBEFOO_01220 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IGBBEFOO_01221 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IGBBEFOO_01222 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
IGBBEFOO_01223 1.21e-98 ohrR - - K - - - COG1846 Transcriptional regulators
IGBBEFOO_01224 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
IGBBEFOO_01226 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
IGBBEFOO_01227 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IGBBEFOO_01228 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IGBBEFOO_01229 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IGBBEFOO_01230 3.8e-175 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IGBBEFOO_01231 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_01232 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
IGBBEFOO_01233 7.28e-144 ykoF - - S - - - YKOF-related Family
IGBBEFOO_01234 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_01235 8.05e-312 ykoH - - T - - - Histidine kinase
IGBBEFOO_01236 3.35e-146 ykoI - - S - - - Peptidase propeptide and YPEB domain
IGBBEFOO_01237 2.24e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
IGBBEFOO_01238 1.45e-08 - - - - - - - -
IGBBEFOO_01240 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
IGBBEFOO_01241 1.49e-70 tnrA - - K - - - transcriptional
IGBBEFOO_01242 1.63e-25 - - - - - - - -
IGBBEFOO_01243 3.04e-36 ykoL - - - - - - -
IGBBEFOO_01244 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
IGBBEFOO_01245 1.19e-281 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IGBBEFOO_01246 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
IGBBEFOO_01247 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IGBBEFOO_01248 0.0 ykoS - - - - - - -
IGBBEFOO_01249 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IGBBEFOO_01250 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
IGBBEFOO_01251 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IGBBEFOO_01252 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
IGBBEFOO_01253 4.48e-153 ykoX - - S - - - membrane-associated protein
IGBBEFOO_01254 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IGBBEFOO_01255 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGBBEFOO_01256 9.33e-219 rsgI - - S - - - Anti-sigma factor N-terminus
IGBBEFOO_01257 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
IGBBEFOO_01258 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
IGBBEFOO_01259 3.4e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IGBBEFOO_01260 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
IGBBEFOO_01262 8.33e-31 ykzE - - - - - - -
IGBBEFOO_01263 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
IGBBEFOO_01264 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_01265 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IGBBEFOO_01267 1.62e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IGBBEFOO_01268 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IGBBEFOO_01269 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IGBBEFOO_01270 4.81e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IGBBEFOO_01271 3.39e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IGBBEFOO_01272 1.07e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IGBBEFOO_01273 4.52e-147 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IGBBEFOO_01274 1.5e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IGBBEFOO_01275 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
IGBBEFOO_01277 5.84e-95 eag - - - - - - -
IGBBEFOO_01278 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IGBBEFOO_01279 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
IGBBEFOO_01280 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IGBBEFOO_01281 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IGBBEFOO_01282 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
IGBBEFOO_01283 4.26e-230 ykvI - - S - - - membrane
IGBBEFOO_01284 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IGBBEFOO_01285 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
IGBBEFOO_01286 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IGBBEFOO_01287 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IGBBEFOO_01288 2.8e-81 ykvN - - K - - - Transcriptional regulator
IGBBEFOO_01289 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IGBBEFOO_01290 2.69e-275 - - - M - - - Glycosyl transferases group 1
IGBBEFOO_01291 1.85e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
IGBBEFOO_01292 2.5e-169 - - - G - - - Glycosyl hydrolases family 18
IGBBEFOO_01293 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
IGBBEFOO_01294 5.43e-35 ykvS - - S - - - protein conserved in bacteria
IGBBEFOO_01295 2.6e-39 - - - - - - - -
IGBBEFOO_01296 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
IGBBEFOO_01297 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IGBBEFOO_01298 5.79e-117 stoA - - CO - - - thiol-disulfide
IGBBEFOO_01299 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IGBBEFOO_01300 3.99e-09 - - - - - - - -
IGBBEFOO_01301 7.85e-266 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IGBBEFOO_01303 3.28e-230 ykvZ - - K - - - Transcriptional regulator
IGBBEFOO_01305 3.41e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
IGBBEFOO_01306 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_01307 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
IGBBEFOO_01308 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGBBEFOO_01309 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_01310 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
IGBBEFOO_01311 5.49e-170 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IGBBEFOO_01312 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IGBBEFOO_01313 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IGBBEFOO_01314 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
IGBBEFOO_01315 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IGBBEFOO_01316 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_01317 5.32e-286 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IGBBEFOO_01318 1.05e-22 - - - - - - - -
IGBBEFOO_01319 4.24e-217 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
IGBBEFOO_01320 3.71e-110 ykyB - - S - - - YkyB-like protein
IGBBEFOO_01321 8.89e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_01322 7.1e-116 ykuD - - S - - - protein conserved in bacteria
IGBBEFOO_01323 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
IGBBEFOO_01324 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_01325 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
IGBBEFOO_01326 1.52e-120 - - - M - - - Peptidoglycan-binding domain 1 protein
IGBBEFOO_01328 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
IGBBEFOO_01329 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
IGBBEFOO_01330 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
IGBBEFOO_01331 7.83e-38 ykzF - - S - - - Antirepressor AbbA
IGBBEFOO_01332 5.15e-100 ykuL - - S - - - CBS domain
IGBBEFOO_01333 6.52e-216 ccpC - - K - - - Transcriptional regulator
IGBBEFOO_01334 7.72e-114 - - - C ko:K03839 - ko00000 Flavodoxin domain
IGBBEFOO_01335 1.33e-226 ykuO - - - - - - -
IGBBEFOO_01336 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
IGBBEFOO_01337 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IGBBEFOO_01338 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IGBBEFOO_01339 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
IGBBEFOO_01340 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
IGBBEFOO_01341 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
IGBBEFOO_01342 6.25e-106 ykuV - - CO - - - thiol-disulfide
IGBBEFOO_01343 4.71e-122 rok - - K - - - Repressor of ComK
IGBBEFOO_01344 1.47e-201 yknT - - - ko:K06437 - ko00000 -
IGBBEFOO_01345 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IGBBEFOO_01346 6.5e-246 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IGBBEFOO_01347 1.05e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
IGBBEFOO_01348 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
IGBBEFOO_01349 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
IGBBEFOO_01350 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IGBBEFOO_01351 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IGBBEFOO_01352 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IGBBEFOO_01353 1.6e-151 yknW - - S - - - Yip1 domain
IGBBEFOO_01354 4.93e-235 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGBBEFOO_01355 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_01356 2.1e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IGBBEFOO_01357 1.49e-175 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_01358 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
IGBBEFOO_01359 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IGBBEFOO_01360 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IGBBEFOO_01361 5.43e-52 ykoA - - - - - - -
IGBBEFOO_01362 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IGBBEFOO_01363 2.99e-217 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IGBBEFOO_01364 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
IGBBEFOO_01365 1.09e-18 - - - S - - - Uncharacterized protein YkpC
IGBBEFOO_01366 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
IGBBEFOO_01367 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
IGBBEFOO_01368 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IGBBEFOO_01369 9.21e-208 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
IGBBEFOO_01370 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IGBBEFOO_01371 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IGBBEFOO_01372 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IGBBEFOO_01373 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
IGBBEFOO_01374 2.03e-187 ykrA - - S - - - hydrolases of the HAD superfamily
IGBBEFOO_01375 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IGBBEFOO_01376 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IGBBEFOO_01377 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
IGBBEFOO_01378 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IGBBEFOO_01379 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IGBBEFOO_01380 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IGBBEFOO_01381 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IGBBEFOO_01382 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
IGBBEFOO_01383 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
IGBBEFOO_01384 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
IGBBEFOO_01385 1.3e-152 yktB - - S - - - Belongs to the UPF0637 family
IGBBEFOO_01386 4.48e-35 ykzI - - - - - - -
IGBBEFOO_01387 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
IGBBEFOO_01388 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
IGBBEFOO_01389 1.28e-223 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IGBBEFOO_01390 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IGBBEFOO_01391 0.0 ylaA - - - - - - -
IGBBEFOO_01392 1.44e-56 ylaB - - - - - - -
IGBBEFOO_01393 4.51e-118 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IGBBEFOO_01395 1.74e-57 ylaE - - - - - - -
IGBBEFOO_01396 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
IGBBEFOO_01397 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IGBBEFOO_01398 4.4e-63 ylaH - - S - - - YlaH-like protein
IGBBEFOO_01399 8.92e-44 ylaI - - S - - - protein conserved in bacteria
IGBBEFOO_01400 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IGBBEFOO_01401 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
IGBBEFOO_01402 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IGBBEFOO_01403 4.25e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IGBBEFOO_01404 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
IGBBEFOO_01405 2.57e-273 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IGBBEFOO_01406 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IGBBEFOO_01407 2.97e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IGBBEFOO_01408 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IGBBEFOO_01409 5.85e-253 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IGBBEFOO_01410 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IGBBEFOO_01411 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IGBBEFOO_01412 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IGBBEFOO_01413 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
IGBBEFOO_01414 1.61e-81 ylbA - - S - - - YugN-like family
IGBBEFOO_01415 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
IGBBEFOO_01416 4.58e-258 ylbC - - S - - - protein with SCP PR1 domains
IGBBEFOO_01417 3.24e-89 ylbD - - S - - - Putative coat protein
IGBBEFOO_01418 1.73e-48 ylbE - - S - - - YlbE-like protein
IGBBEFOO_01419 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
IGBBEFOO_01420 4.36e-52 ylbG - - S - - - UPF0298 protein
IGBBEFOO_01421 2.12e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
IGBBEFOO_01422 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IGBBEFOO_01423 2.73e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
IGBBEFOO_01424 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IGBBEFOO_01425 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IGBBEFOO_01426 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
IGBBEFOO_01428 1.7e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
IGBBEFOO_01429 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IGBBEFOO_01430 5.75e-108 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IGBBEFOO_01431 3.26e-116 ylbP - - K - - - n-acetyltransferase
IGBBEFOO_01432 1.66e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IGBBEFOO_01433 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IGBBEFOO_01434 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IGBBEFOO_01435 4.97e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IGBBEFOO_01436 3.42e-68 ftsL - - D - - - Essential cell division protein
IGBBEFOO_01437 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IGBBEFOO_01438 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
IGBBEFOO_01439 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IGBBEFOO_01440 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IGBBEFOO_01441 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IGBBEFOO_01442 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IGBBEFOO_01443 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IGBBEFOO_01444 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
IGBBEFOO_01445 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IGBBEFOO_01446 3.45e-146 ylxW - - S - - - protein conserved in bacteria
IGBBEFOO_01447 1.06e-132 ylxX - - S - - - protein conserved in bacteria
IGBBEFOO_01448 5.37e-76 sbp - - S - - - small basic protein
IGBBEFOO_01449 8.45e-300 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IGBBEFOO_01450 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IGBBEFOO_01451 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
IGBBEFOO_01452 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IGBBEFOO_01453 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGBBEFOO_01454 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGBBEFOO_01455 3.84e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IGBBEFOO_01456 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
IGBBEFOO_01457 3.58e-51 ylmC - - S - - - sporulation protein
IGBBEFOO_01458 5.53e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
IGBBEFOO_01459 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IGBBEFOO_01460 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IGBBEFOO_01461 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
IGBBEFOO_01462 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
IGBBEFOO_01463 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
IGBBEFOO_01464 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IGBBEFOO_01465 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
IGBBEFOO_01466 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IGBBEFOO_01467 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IGBBEFOO_01468 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IGBBEFOO_01469 2.24e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
IGBBEFOO_01470 4.4e-215 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IGBBEFOO_01471 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IGBBEFOO_01472 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IGBBEFOO_01473 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
IGBBEFOO_01474 3.84e-185 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IGBBEFOO_01475 1.33e-224 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IGBBEFOO_01476 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IGBBEFOO_01477 3.8e-150 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IGBBEFOO_01479 3.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IGBBEFOO_01480 7.32e-230 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
IGBBEFOO_01481 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IGBBEFOO_01482 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IGBBEFOO_01483 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IGBBEFOO_01484 4.33e-189 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
IGBBEFOO_01485 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
IGBBEFOO_01486 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IGBBEFOO_01487 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
IGBBEFOO_01488 8.41e-202 yloC - - S - - - stress-induced protein
IGBBEFOO_01489 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
IGBBEFOO_01490 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IGBBEFOO_01491 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IGBBEFOO_01492 4.59e-289 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IGBBEFOO_01493 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IGBBEFOO_01494 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IGBBEFOO_01495 2.21e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IGBBEFOO_01496 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IGBBEFOO_01497 3.73e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IGBBEFOO_01498 3.03e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IGBBEFOO_01499 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IGBBEFOO_01500 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IGBBEFOO_01501 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IGBBEFOO_01502 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IGBBEFOO_01503 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IGBBEFOO_01504 3.65e-78 yloU - - S - - - protein conserved in bacteria
IGBBEFOO_01505 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
IGBBEFOO_01506 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IGBBEFOO_01507 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IGBBEFOO_01508 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IGBBEFOO_01509 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IGBBEFOO_01510 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IGBBEFOO_01511 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IGBBEFOO_01512 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IGBBEFOO_01513 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGBBEFOO_01514 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IGBBEFOO_01515 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IGBBEFOO_01516 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IGBBEFOO_01517 1.67e-114 - - - - - - - -
IGBBEFOO_01518 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IGBBEFOO_01519 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IGBBEFOO_01520 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IGBBEFOO_01521 2.95e-50 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IGBBEFOO_01522 5.89e-81 ylqD - - S - - - YlqD protein
IGBBEFOO_01523 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IGBBEFOO_01524 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IGBBEFOO_01525 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IGBBEFOO_01526 1.2e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IGBBEFOO_01527 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGBBEFOO_01528 0.0 ylqG - - - - - - -
IGBBEFOO_01529 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
IGBBEFOO_01530 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IGBBEFOO_01531 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IGBBEFOO_01532 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
IGBBEFOO_01533 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IGBBEFOO_01534 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IGBBEFOO_01535 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
IGBBEFOO_01536 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IGBBEFOO_01537 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IGBBEFOO_01538 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IGBBEFOO_01539 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IGBBEFOO_01540 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
IGBBEFOO_01541 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
IGBBEFOO_01542 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
IGBBEFOO_01543 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IGBBEFOO_01544 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
IGBBEFOO_01545 2.11e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IGBBEFOO_01546 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
IGBBEFOO_01547 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
IGBBEFOO_01548 2.31e-314 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
IGBBEFOO_01549 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
IGBBEFOO_01550 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
IGBBEFOO_01551 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
IGBBEFOO_01552 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IGBBEFOO_01553 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IGBBEFOO_01554 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
IGBBEFOO_01555 5.54e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
IGBBEFOO_01556 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
IGBBEFOO_01557 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
IGBBEFOO_01558 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
IGBBEFOO_01559 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IGBBEFOO_01560 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IGBBEFOO_01561 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
IGBBEFOO_01562 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
IGBBEFOO_01563 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IGBBEFOO_01564 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
IGBBEFOO_01565 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
IGBBEFOO_01566 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IGBBEFOO_01567 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IGBBEFOO_01568 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGBBEFOO_01569 6.91e-101 ylxL - - - - - - -
IGBBEFOO_01570 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IGBBEFOO_01571 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IGBBEFOO_01572 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IGBBEFOO_01573 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IGBBEFOO_01574 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IGBBEFOO_01575 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IGBBEFOO_01576 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IGBBEFOO_01577 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IGBBEFOO_01578 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IGBBEFOO_01579 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGBBEFOO_01580 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IGBBEFOO_01581 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IGBBEFOO_01582 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
IGBBEFOO_01583 6.16e-63 ylxQ - - J - - - ribosomal protein
IGBBEFOO_01584 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IGBBEFOO_01585 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
IGBBEFOO_01586 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IGBBEFOO_01587 5.18e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IGBBEFOO_01588 1.63e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IGBBEFOO_01589 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IGBBEFOO_01590 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IGBBEFOO_01591 1.29e-235 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
IGBBEFOO_01592 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
IGBBEFOO_01593 1.53e-56 ymxH - - S - - - YlmC YmxH family
IGBBEFOO_01594 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
IGBBEFOO_01595 9.94e-142 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IGBBEFOO_01596 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IGBBEFOO_01597 1.2e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IGBBEFOO_01598 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IGBBEFOO_01599 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IGBBEFOO_01600 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
IGBBEFOO_01601 4.94e-44 - - - S - - - YlzJ-like protein
IGBBEFOO_01602 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IGBBEFOO_01603 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_01604 2.08e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_01605 2.96e-302 albE - - S - - - Peptidase M16
IGBBEFOO_01606 2.37e-309 ymfH - - S - - - zinc protease
IGBBEFOO_01607 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IGBBEFOO_01608 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
IGBBEFOO_01609 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
IGBBEFOO_01610 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
IGBBEFOO_01611 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IGBBEFOO_01612 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IGBBEFOO_01613 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IGBBEFOO_01614 8.43e-282 pbpX - - V - - - Beta-lactamase
IGBBEFOO_01615 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IGBBEFOO_01616 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
IGBBEFOO_01617 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
IGBBEFOO_01618 3.02e-255 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IGBBEFOO_01619 1.02e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IGBBEFOO_01620 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IGBBEFOO_01621 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
IGBBEFOO_01622 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
IGBBEFOO_01623 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IGBBEFOO_01624 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IGBBEFOO_01625 7.19e-93 - - - S - - - Regulatory protein YrvL
IGBBEFOO_01627 1.38e-127 ymcC - - S - - - Membrane
IGBBEFOO_01628 2.94e-141 pksA - - K - - - Transcriptional regulator
IGBBEFOO_01629 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
IGBBEFOO_01630 1.31e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IGBBEFOO_01631 2.08e-239 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
IGBBEFOO_01632 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IGBBEFOO_01633 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
IGBBEFOO_01634 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IGBBEFOO_01635 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IGBBEFOO_01636 2.48e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
IGBBEFOO_01637 2.69e-177 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IGBBEFOO_01638 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IGBBEFOO_01639 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IGBBEFOO_01640 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IGBBEFOO_01641 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IGBBEFOO_01642 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
IGBBEFOO_01643 2.49e-297 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IGBBEFOO_01644 2.8e-81 ymzB - - - - - - -
IGBBEFOO_01645 4.8e-210 - - - S - - - Metallo-beta-lactamase superfamily
IGBBEFOO_01646 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
IGBBEFOO_01647 3.96e-163 ymaC - - S - - - Replication protein
IGBBEFOO_01648 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
IGBBEFOO_01649 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
IGBBEFOO_01650 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IGBBEFOO_01652 5.41e-76 ymaF - - S - - - YmaF family
IGBBEFOO_01653 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IGBBEFOO_01654 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IGBBEFOO_01655 8.07e-32 - - - - - - - -
IGBBEFOO_01656 1.2e-30 ymzA - - - - - - -
IGBBEFOO_01657 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IGBBEFOO_01658 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGBBEFOO_01659 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGBBEFOO_01660 2.24e-141 - - - - - - - -
IGBBEFOO_01661 1.72e-151 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IGBBEFOO_01662 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
IGBBEFOO_01663 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IGBBEFOO_01664 5.82e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IGBBEFOO_01665 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
IGBBEFOO_01666 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IGBBEFOO_01667 2.95e-14 - - - - - - - -
IGBBEFOO_01668 2.61e-40 - - - - - - - -
IGBBEFOO_01669 7.13e-52 - - - - - - - -
IGBBEFOO_01670 5.4e-105 - - - G - - - regulation of fungal-type cell wall biogenesis
IGBBEFOO_01671 1.97e-186 ynaC - - - - - - -
IGBBEFOO_01672 7.56e-129 ynaD - - J - - - Acetyltransferase (GNAT) domain
IGBBEFOO_01673 1.65e-160 - - - S - - - Domain of unknown function (DUF3885)
IGBBEFOO_01674 1.06e-80 ynaF - - - - - - -
IGBBEFOO_01677 4.32e-110 - - - E - - - phosphoribosylanthranilate isomerase activity
IGBBEFOO_01678 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
IGBBEFOO_01679 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IGBBEFOO_01680 3.15e-278 xylR - - GK - - - ROK family
IGBBEFOO_01681 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
IGBBEFOO_01682 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
IGBBEFOO_01683 9.1e-148 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IGBBEFOO_01684 3.64e-313 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IGBBEFOO_01685 3.05e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IGBBEFOO_01686 3.44e-110 - - - S - - - Protein of unknown function (DUF2691)
IGBBEFOO_01687 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IGBBEFOO_01688 7.54e-22 - - - - - - - -
IGBBEFOO_01691 7.03e-213 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IGBBEFOO_01693 1.55e-172 - - - S - - - Domain of unknown function, YrpD
IGBBEFOO_01696 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
IGBBEFOO_01697 8.92e-96 - - - - - - - -
IGBBEFOO_01698 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
IGBBEFOO_01701 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IGBBEFOO_01702 2.38e-251 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
IGBBEFOO_01703 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
IGBBEFOO_01704 9.15e-199 yndG - - S - - - DoxX-like family
IGBBEFOO_01705 1.26e-151 - - - S - - - Domain of unknown function (DUF4166)
IGBBEFOO_01706 0.0 yndJ - - S - - - YndJ-like protein
IGBBEFOO_01708 1.68e-177 yndL - - S - - - Replication protein
IGBBEFOO_01709 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
IGBBEFOO_01710 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IGBBEFOO_01712 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IGBBEFOO_01713 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IGBBEFOO_01714 3.97e-145 yneB - - L - - - resolvase
IGBBEFOO_01715 1.15e-43 ynzC - - S - - - UPF0291 protein
IGBBEFOO_01716 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IGBBEFOO_01717 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
IGBBEFOO_01718 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
IGBBEFOO_01719 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
IGBBEFOO_01720 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
IGBBEFOO_01721 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
IGBBEFOO_01722 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
IGBBEFOO_01723 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
IGBBEFOO_01724 1.21e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
IGBBEFOO_01725 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
IGBBEFOO_01726 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
IGBBEFOO_01727 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IGBBEFOO_01728 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IGBBEFOO_01729 9.26e-10 - - - S - - - Fur-regulated basic protein B
IGBBEFOO_01731 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
IGBBEFOO_01732 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
IGBBEFOO_01733 1.63e-71 yneQ - - - - - - -
IGBBEFOO_01734 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
IGBBEFOO_01735 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IGBBEFOO_01736 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
IGBBEFOO_01737 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IGBBEFOO_01738 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IGBBEFOO_01739 1.82e-18 - - - - - - - -
IGBBEFOO_01740 1.06e-75 ynfC - - - - - - -
IGBBEFOO_01741 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IGBBEFOO_01742 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
IGBBEFOO_01744 0.0 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
IGBBEFOO_01745 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IGBBEFOO_01746 1.04e-104 yngA - - S - - - membrane
IGBBEFOO_01747 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IGBBEFOO_01748 2.01e-134 yngC - - S - - - membrane-associated protein
IGBBEFOO_01749 4.46e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
IGBBEFOO_01750 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IGBBEFOO_01751 1.48e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
IGBBEFOO_01752 7.02e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
IGBBEFOO_01753 1.23e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
IGBBEFOO_01754 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
IGBBEFOO_01755 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IGBBEFOO_01756 1.31e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IGBBEFOO_01757 4.3e-41 - - - S - - - Family of unknown function (DUF5367)
IGBBEFOO_01759 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
IGBBEFOO_01760 2.12e-84 yngL - - S - - - Protein of unknown function (DUF1360)
IGBBEFOO_01761 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
IGBBEFOO_01762 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGBBEFOO_01763 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGBBEFOO_01764 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGBBEFOO_01765 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGBBEFOO_01766 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IGBBEFOO_01767 2.54e-245 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IGBBEFOO_01768 9.8e-313 yoeA - - V - - - MATE efflux family protein
IGBBEFOO_01769 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
IGBBEFOO_01771 1.14e-124 - - - L - - - Integrase
IGBBEFOO_01772 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
IGBBEFOO_01773 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IGBBEFOO_01774 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_01775 7.23e-238 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IGBBEFOO_01776 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IGBBEFOO_01777 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
IGBBEFOO_01778 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_01779 8.13e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IGBBEFOO_01780 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IGBBEFOO_01781 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IGBBEFOO_01782 7.94e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_01783 8.39e-57 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
IGBBEFOO_01784 1.34e-185 yoxB - - - - - - -
IGBBEFOO_01785 5.91e-125 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IGBBEFOO_01786 1.11e-300 yoaB - - EGP - - - the major facilitator superfamily
IGBBEFOO_01787 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
IGBBEFOO_01788 3.41e-243 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGBBEFOO_01789 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IGBBEFOO_01790 2.08e-44 yoaF - - - - - - -
IGBBEFOO_01792 1.25e-20 - - - - - - - -
IGBBEFOO_01793 8.23e-62 - - - S - - - Protein of unknown function (DUF4025)
IGBBEFOO_01794 0.0 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
IGBBEFOO_01795 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
IGBBEFOO_01796 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
IGBBEFOO_01797 1.79e-145 yoaK - - S - - - Membrane
IGBBEFOO_01798 1.5e-254 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
IGBBEFOO_01799 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
IGBBEFOO_01801 1.95e-296 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IGBBEFOO_01803 4.7e-188 yoaP - - K - - - YoaP-like
IGBBEFOO_01804 7.38e-88 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
IGBBEFOO_01805 2.36e-116 - - - - - - - -
IGBBEFOO_01806 3.63e-218 yoaR - - V - - - vancomycin resistance protein
IGBBEFOO_01807 1.6e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
IGBBEFOO_01808 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_01809 6.92e-192 yoaT - - S - - - Protein of unknown function (DUF817)
IGBBEFOO_01810 6.67e-203 yoaU - - K - - - LysR substrate binding domain
IGBBEFOO_01811 1.11e-202 yoaV - - EG - - - EamA-like transporter family
IGBBEFOO_01812 6.84e-103 yoaW - - - - - - -
IGBBEFOO_01813 3.88e-153 lin0465 - - S - - - DJ-1/PfpI family
IGBBEFOO_01814 9.26e-218 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
IGBBEFOO_01818 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IGBBEFOO_01819 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
IGBBEFOO_01820 6.27e-51 - - - S - - - TM2 domain
IGBBEFOO_01821 3.92e-76 - - - K - - - Helix-turn-helix
IGBBEFOO_01823 1.21e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
IGBBEFOO_01824 1.92e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
IGBBEFOO_01825 6.85e-229 - - - - - - - -
IGBBEFOO_01826 1.36e-08 - - - - - - - -
IGBBEFOO_01830 6.23e-267 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IGBBEFOO_01832 6.17e-158 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IGBBEFOO_01833 1.52e-79 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IGBBEFOO_01834 2.05e-51 - - - S - - - YolD-like protein
IGBBEFOO_01835 2.08e-64 - - - - - - - -
IGBBEFOO_01836 0.0 - - - K - - - Psort location Cytoplasmic, score
IGBBEFOO_01837 3.58e-202 - - - - - - - -
IGBBEFOO_01838 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IGBBEFOO_01839 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IGBBEFOO_01840 4.3e-136 yokH - - G - - - SMI1 / KNR4 family
IGBBEFOO_01841 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
IGBBEFOO_01842 0.0 yobO - - M - - - Pectate lyase superfamily protein
IGBBEFOO_01843 2.21e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
IGBBEFOO_01844 5.23e-175 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
IGBBEFOO_01845 1.29e-183 - - - J - - - FR47-like protein
IGBBEFOO_01846 9.22e-129 yobS - - K - - - Transcriptional regulator
IGBBEFOO_01847 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IGBBEFOO_01848 1.55e-114 - - - K - - - Bacterial transcription activator, effector binding domain
IGBBEFOO_01849 2.05e-229 yobV - - K - - - WYL domain
IGBBEFOO_01850 7.69e-123 yobW - - - - - - -
IGBBEFOO_01851 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
IGBBEFOO_01852 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IGBBEFOO_01853 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
IGBBEFOO_01854 4.49e-186 - - - - - - - -
IGBBEFOO_01855 1.32e-122 yocC - - - - - - -
IGBBEFOO_01856 1.21e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
IGBBEFOO_01857 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IGBBEFOO_01858 1.22e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_01859 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IGBBEFOO_01860 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
IGBBEFOO_01861 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IGBBEFOO_01862 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IGBBEFOO_01863 1.42e-107 yocK - - T - - - general stress protein
IGBBEFOO_01864 3.02e-70 yocL - - - - - - -
IGBBEFOO_01865 7.29e-46 - - - - - - - -
IGBBEFOO_01866 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IGBBEFOO_01867 2.94e-55 yozN - - - - - - -
IGBBEFOO_01868 1.83e-49 yocN - - - - - - -
IGBBEFOO_01869 2.17e-74 yozO - - S - - - Bacterial PH domain
IGBBEFOO_01870 1.91e-42 yozC - - - - - - -
IGBBEFOO_01871 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IGBBEFOO_01872 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
IGBBEFOO_01873 3.35e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
IGBBEFOO_01874 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IGBBEFOO_01875 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
IGBBEFOO_01876 3.16e-265 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IGBBEFOO_01877 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IGBBEFOO_01878 0.0 yojO - - P - - - Von Willebrand factor
IGBBEFOO_01879 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
IGBBEFOO_01880 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IGBBEFOO_01881 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IGBBEFOO_01882 5.62e-294 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
IGBBEFOO_01883 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IGBBEFOO_01885 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
IGBBEFOO_01886 2.49e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IGBBEFOO_01887 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
IGBBEFOO_01888 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
IGBBEFOO_01889 1.85e-58 - - - - - - - -
IGBBEFOO_01890 1.21e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
IGBBEFOO_01891 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
IGBBEFOO_01892 1.95e-14 - - - - - - - -
IGBBEFOO_01893 1.01e-293 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IGBBEFOO_01894 2.05e-86 iolK - - S - - - tautomerase
IGBBEFOO_01895 1.37e-76 yodB - - K - - - transcriptional
IGBBEFOO_01896 1.92e-140 yodC - - C - - - nitroreductase
IGBBEFOO_01897 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
IGBBEFOO_01898 1.18e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IGBBEFOO_01899 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
IGBBEFOO_01900 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IGBBEFOO_01901 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IGBBEFOO_01902 6.38e-168 yodH - - Q - - - Methyltransferase
IGBBEFOO_01903 2.93e-42 yodI - - - - - - -
IGBBEFOO_01904 1.62e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IGBBEFOO_01905 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
IGBBEFOO_01906 2.08e-12 - - - - - - - -
IGBBEFOO_01907 1.17e-71 yodL - - S - - - YodL-like
IGBBEFOO_01908 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IGBBEFOO_01909 5.18e-34 yozD - - S - - - YozD-like protein
IGBBEFOO_01911 3.84e-161 yodN - - - - - - -
IGBBEFOO_01912 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
IGBBEFOO_01913 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
IGBBEFOO_01914 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
IGBBEFOO_01915 9.5e-200 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
IGBBEFOO_01916 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
IGBBEFOO_01917 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IGBBEFOO_01919 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IGBBEFOO_01922 2.06e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
IGBBEFOO_01923 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
IGBBEFOO_01924 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
IGBBEFOO_01925 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
IGBBEFOO_01926 2.95e-240 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
IGBBEFOO_01927 4.17e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
IGBBEFOO_01928 1.13e-82 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IGBBEFOO_01930 1.31e-139 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IGBBEFOO_01939 6.52e-216 - - - S - - - Calcineurin-like phosphoesterase
IGBBEFOO_01940 2.24e-41 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IGBBEFOO_01945 2.85e-107 - - - L - - - Bacterial transcription activator, effector binding domain
IGBBEFOO_01946 3.02e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IGBBEFOO_01947 2.34e-51 - - - O - - - Glutaredoxin
IGBBEFOO_01948 1.12e-87 - - - S - - - Ribonucleotide reductase, small chain
IGBBEFOO_01949 3.73e-126 - - - L - - - HNH endonuclease
IGBBEFOO_01950 1.59e-139 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGBBEFOO_01951 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGBBEFOO_01952 1.71e-160 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGBBEFOO_01953 7.75e-87 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IGBBEFOO_01970 0.0 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
IGBBEFOO_01972 1.71e-126 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IGBBEFOO_01973 3.92e-115 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
IGBBEFOO_01978 9.54e-147 - - - S - - - protein conserved in bacteria
IGBBEFOO_01979 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IGBBEFOO_01980 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IGBBEFOO_01981 3.45e-288 - - - L - - - DNA primase activity
IGBBEFOO_01982 0.0 - - - J - - - DnaB-like helicase C terminal domain
IGBBEFOO_01983 1.1e-112 - - - - - - - -
IGBBEFOO_01984 6.35e-229 - - - L - - - AAA domain
IGBBEFOO_01985 2.37e-219 - - - - - - - -
IGBBEFOO_01990 0.0 - - - M - - - Parallel beta-helix repeats
IGBBEFOO_01991 1.83e-192 - - - S - - - Pfam:DUF867
IGBBEFOO_01994 2.62e-167 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
IGBBEFOO_01995 3.73e-199 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
IGBBEFOO_01996 6.17e-103 - - - - - - - -
IGBBEFOO_02003 3.88e-60 - - - - - - - -
IGBBEFOO_02005 9.17e-126 - - - S - - - Protein of unknown function (DUF1273)
IGBBEFOO_02007 1.16e-102 yoqH - - M - - - LysM domain
IGBBEFOO_02010 2.65e-15 - - - S - - - Protein of unknown function (DUF2815)
IGBBEFOO_02011 2.12e-175 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
IGBBEFOO_02017 0.000573 - - - S - - - YopX protein
IGBBEFOO_02022 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_02023 2.89e-226 - - - - - - - -
IGBBEFOO_02024 0.0 - - - S - - - DNA-sulfur modification-associated
IGBBEFOO_02025 2.04e-254 - - - L - - - Belongs to the 'phage' integrase family
IGBBEFOO_02030 7.95e-135 - - - - - - - -
IGBBEFOO_02032 8.39e-125 - - - - - - - -
IGBBEFOO_02033 2.68e-124 - - - S - - - Super-infection exclusion protein B
IGBBEFOO_02039 0.0 - - - - - - - -
IGBBEFOO_02040 7.56e-48 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IGBBEFOO_02041 0.0 - - - - - - - -
IGBBEFOO_02043 1.07e-305 - - - - - - - -
IGBBEFOO_02046 6.64e-73 bldD - - K ko:K07110,ko:K21572 - ko00000,ko02000,ko03000 domain, Protein
IGBBEFOO_02049 0.0 - - - - - - - -
IGBBEFOO_02050 7.27e-56 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IGBBEFOO_02052 2.29e-293 - - - - - - - -
IGBBEFOO_02055 4.45e-225 - - - - - - - -
IGBBEFOO_02056 0.0 - - - S - - - Terminase-like family
IGBBEFOO_02057 0.0 - - - - - - - -
IGBBEFOO_02058 0.0 - - - - - - - -
IGBBEFOO_02059 1.24e-122 - - - - - - - -
IGBBEFOO_02060 5.93e-237 - - - - - - - -
IGBBEFOO_02061 8.05e-106 - - - - - - - -
IGBBEFOO_02062 8.95e-91 - - - - - - - -
IGBBEFOO_02064 9.48e-157 - - - - - - - -
IGBBEFOO_02065 4.38e-118 - - - - - - - -
IGBBEFOO_02066 2.4e-169 - - - - - - - -
IGBBEFOO_02067 1.58e-145 - - - - - - - -
IGBBEFOO_02070 2.22e-76 - - - - - - - -
IGBBEFOO_02071 4.46e-229 - - - - - - - -
IGBBEFOO_02074 1.65e-112 - - - - - - - -
IGBBEFOO_02075 2e-94 - - - - - - - -
IGBBEFOO_02076 1.73e-247 - - - A - - - Belongs to the 'phage' integrase family
IGBBEFOO_02081 5.66e-159 - - - - - - - -
IGBBEFOO_02082 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IGBBEFOO_02083 1.7e-186 - - - S - - - Phage tail protein
IGBBEFOO_02084 0.0 - - - S - - - Pfam Transposase IS66
IGBBEFOO_02085 9.28e-166 - - - - - - - -
IGBBEFOO_02086 0.0 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
IGBBEFOO_02087 1.31e-210 - - - - - - - -
IGBBEFOO_02089 7.44e-257 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
IGBBEFOO_02090 1.42e-43 bhlA - - S - - - BhlA holin family
IGBBEFOO_02091 3.04e-53 - - - S - - - SPP1 phage holin
IGBBEFOO_02092 5.12e-96 - - - O ko:K03611 - ko00000,ko03110 protein disulfide oxidoreductase activity
IGBBEFOO_02093 6.04e-309 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IGBBEFOO_02094 3.44e-91 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 cell redox homeostasis
IGBBEFOO_02095 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 Peptidase C39 family
IGBBEFOO_02098 2.97e-306 - - - S - - - damaged DNA binding
IGBBEFOO_02099 7.69e-73 - - - S - - - YolD-like protein
IGBBEFOO_02100 1.42e-55 - - - - - - - -
IGBBEFOO_02104 5.26e-128 - - - J - - - Acetyltransferase (GNAT) domain
IGBBEFOO_02105 5.38e-142 yokK - - S - - - SMI1 / KNR4 family
IGBBEFOO_02106 9.26e-123 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
IGBBEFOO_02107 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
IGBBEFOO_02108 2.64e-119 yokH - - G - - - SMI1 / KNR4 family
IGBBEFOO_02109 5.27e-261 - - - - - - - -
IGBBEFOO_02110 2.55e-178 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IGBBEFOO_02111 6.83e-109 - - - S - - - Bacterial PH domain
IGBBEFOO_02112 8.79e-199 yokD 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 aminoglycoside
IGBBEFOO_02115 5.1e-123 - - - - - - - -
IGBBEFOO_02116 4.93e-153 - - - - - - - -
IGBBEFOO_02117 0.0 yokA - - L - - - Recombinase
IGBBEFOO_02118 1.76e-124 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IGBBEFOO_02119 3.52e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IGBBEFOO_02120 8.41e-134 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IGBBEFOO_02121 4.14e-94 ypoP - - K - - - transcriptional
IGBBEFOO_02122 3.49e-290 mepA - - V - - - MATE efflux family protein
IGBBEFOO_02123 2.13e-40 ypmT - - S - - - Uncharacterized ympT
IGBBEFOO_02124 6.8e-129 ypmS - - S - - - protein conserved in bacteria
IGBBEFOO_02125 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
IGBBEFOO_02126 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IGBBEFOO_02127 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
IGBBEFOO_02128 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IGBBEFOO_02129 1.4e-236 yplP - - K - - - Transcriptional regulator
IGBBEFOO_02130 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
IGBBEFOO_02131 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IGBBEFOO_02132 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IGBBEFOO_02133 7.27e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IGBBEFOO_02134 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IGBBEFOO_02135 3.47e-148 ypjP - - S - - - YpjP-like protein
IGBBEFOO_02136 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
IGBBEFOO_02137 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
IGBBEFOO_02138 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
IGBBEFOO_02139 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
IGBBEFOO_02140 2.52e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
IGBBEFOO_02141 1.89e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IGBBEFOO_02142 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IGBBEFOO_02143 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IGBBEFOO_02144 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IGBBEFOO_02145 1.17e-22 degR - - - - - - -
IGBBEFOO_02146 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
IGBBEFOO_02147 7.99e-41 ypeQ - - S - - - Zinc-finger
IGBBEFOO_02148 4e-163 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
IGBBEFOO_02149 2.4e-138 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IGBBEFOO_02150 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
IGBBEFOO_02151 5.23e-05 - - - - ko:K06429 - ko00000 -
IGBBEFOO_02152 2.26e-213 ypcP - - L - - - 5'3' exonuclease
IGBBEFOO_02153 1.08e-11 - - - - - - - -
IGBBEFOO_02154 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
IGBBEFOO_02155 0.0 ypbR - - S - - - Dynamin family
IGBBEFOO_02156 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
IGBBEFOO_02157 4.55e-266 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
IGBBEFOO_02158 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
IGBBEFOO_02159 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IGBBEFOO_02160 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IGBBEFOO_02161 1e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IGBBEFOO_02162 2.53e-133 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
IGBBEFOO_02163 6.95e-238 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
IGBBEFOO_02164 1.92e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
IGBBEFOO_02165 1.25e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IGBBEFOO_02166 2.05e-179 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_02167 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
IGBBEFOO_02169 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IGBBEFOO_02170 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IGBBEFOO_02171 3.41e-130 ypsA - - S - - - Belongs to the UPF0398 family
IGBBEFOO_02172 7.21e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
IGBBEFOO_02173 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IGBBEFOO_02174 2.34e-113 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
IGBBEFOO_02175 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IGBBEFOO_02176 8.72e-68 yppG - - S - - - YppG-like protein
IGBBEFOO_02177 9.21e-11 - - - S - - - YppF-like protein
IGBBEFOO_02178 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
IGBBEFOO_02181 4.54e-241 yppC - - S - - - Protein of unknown function (DUF2515)
IGBBEFOO_02182 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IGBBEFOO_02183 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IGBBEFOO_02184 1.43e-121 ypoC - - - - - - -
IGBBEFOO_02185 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IGBBEFOO_02186 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
IGBBEFOO_02187 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
IGBBEFOO_02188 1.07e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IGBBEFOO_02189 2.27e-103 ypmB - - S - - - protein conserved in bacteria
IGBBEFOO_02190 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
IGBBEFOO_02191 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IGBBEFOO_02192 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IGBBEFOO_02193 1.34e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IGBBEFOO_02194 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IGBBEFOO_02195 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IGBBEFOO_02196 1.41e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IGBBEFOO_02197 1.04e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
IGBBEFOO_02198 6.61e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
IGBBEFOO_02199 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
IGBBEFOO_02200 8.38e-190 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IGBBEFOO_02201 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
IGBBEFOO_02202 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IGBBEFOO_02203 6.84e-183 ypjB - - S - - - sporulation protein
IGBBEFOO_02204 1.63e-125 ypjA - - S - - - membrane
IGBBEFOO_02205 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
IGBBEFOO_02206 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
IGBBEFOO_02207 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
IGBBEFOO_02208 4.75e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
IGBBEFOO_02209 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
IGBBEFOO_02210 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
IGBBEFOO_02211 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IGBBEFOO_02212 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IGBBEFOO_02213 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IGBBEFOO_02214 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IGBBEFOO_02215 9.33e-295 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IGBBEFOO_02216 2.82e-153 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
IGBBEFOO_02217 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IGBBEFOO_02218 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IGBBEFOO_02219 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IGBBEFOO_02220 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IGBBEFOO_02221 8.48e-265 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IGBBEFOO_02222 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IGBBEFOO_02223 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
IGBBEFOO_02224 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IGBBEFOO_02225 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IGBBEFOO_02226 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IGBBEFOO_02227 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IGBBEFOO_02228 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IGBBEFOO_02229 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
IGBBEFOO_02230 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IGBBEFOO_02231 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IGBBEFOO_02232 9.07e-178 yphF - - - - - - -
IGBBEFOO_02233 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
IGBBEFOO_02234 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IGBBEFOO_02235 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IGBBEFOO_02236 8.69e-40 ypzH - - - - - - -
IGBBEFOO_02237 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
IGBBEFOO_02238 2.73e-134 yphA - - - - - - -
IGBBEFOO_02239 1.13e-11 - - - S - - - YpzI-like protein
IGBBEFOO_02240 8.41e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IGBBEFOO_02241 9.5e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IGBBEFOO_02242 1.73e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IGBBEFOO_02243 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
IGBBEFOO_02244 4.63e-144 ypfA - - M - - - Flagellar protein YcgR
IGBBEFOO_02245 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
IGBBEFOO_02246 4.88e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
IGBBEFOO_02247 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
IGBBEFOO_02248 1.62e-227 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
IGBBEFOO_02249 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IGBBEFOO_02250 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IGBBEFOO_02251 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IGBBEFOO_02252 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
IGBBEFOO_02253 5.04e-148 ypbE - - M - - - Lysin motif
IGBBEFOO_02254 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
IGBBEFOO_02255 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IGBBEFOO_02256 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
IGBBEFOO_02257 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
IGBBEFOO_02258 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IGBBEFOO_02259 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGBBEFOO_02260 2.89e-175 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IGBBEFOO_02261 2.7e-257 rsiX - - - - - - -
IGBBEFOO_02262 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IGBBEFOO_02263 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_02264 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_02265 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IGBBEFOO_02266 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
IGBBEFOO_02267 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IGBBEFOO_02268 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IGBBEFOO_02269 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
IGBBEFOO_02270 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
IGBBEFOO_02271 4.11e-273 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IGBBEFOO_02272 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
IGBBEFOO_02273 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IGBBEFOO_02274 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IGBBEFOO_02275 3.18e-123 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
IGBBEFOO_02276 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IGBBEFOO_02277 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IGBBEFOO_02278 3.12e-292 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IGBBEFOO_02279 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
IGBBEFOO_02280 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IGBBEFOO_02281 2.96e-72 ypuD - - - - - - -
IGBBEFOO_02282 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IGBBEFOO_02283 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
IGBBEFOO_02285 3.82e-09 - - - S - - - SNARE associated Golgi protein
IGBBEFOO_02287 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IGBBEFOO_02288 2.67e-193 ypuA - - S - - - Secreted protein
IGBBEFOO_02289 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IGBBEFOO_02290 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
IGBBEFOO_02291 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
IGBBEFOO_02292 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
IGBBEFOO_02293 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
IGBBEFOO_02294 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
IGBBEFOO_02295 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
IGBBEFOO_02296 5.72e-144 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
IGBBEFOO_02297 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGBBEFOO_02298 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IGBBEFOO_02299 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
IGBBEFOO_02300 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IGBBEFOO_02301 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IGBBEFOO_02302 2.89e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
IGBBEFOO_02303 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
IGBBEFOO_02304 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
IGBBEFOO_02305 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IGBBEFOO_02306 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IGBBEFOO_02307 3.73e-44 yqkK - - - - - - -
IGBBEFOO_02308 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IGBBEFOO_02309 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IGBBEFOO_02310 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
IGBBEFOO_02311 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
IGBBEFOO_02312 3.18e-77 ansR - - K - - - Transcriptional regulator
IGBBEFOO_02313 2.62e-283 yqxK - - L - - - DNA helicase
IGBBEFOO_02314 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
IGBBEFOO_02315 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
IGBBEFOO_02316 9.26e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IGBBEFOO_02317 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
IGBBEFOO_02318 4.29e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IGBBEFOO_02319 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
IGBBEFOO_02320 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
IGBBEFOO_02321 2.89e-251 yqkA - - K - - - GrpB protein
IGBBEFOO_02322 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
IGBBEFOO_02323 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
IGBBEFOO_02324 1.87e-65 yqiX - - S - - - YolD-like protein
IGBBEFOO_02325 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IGBBEFOO_02327 1.08e-289 yqjV - - G - - - Major Facilitator Superfamily
IGBBEFOO_02329 1.33e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGBBEFOO_02330 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IGBBEFOO_02331 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
IGBBEFOO_02332 3.41e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_02333 3.98e-230 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IGBBEFOO_02334 6.84e-190 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IGBBEFOO_02335 0.0 rocB - - E - - - arginine degradation protein
IGBBEFOO_02336 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IGBBEFOO_02337 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IGBBEFOO_02338 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IGBBEFOO_02339 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IGBBEFOO_02340 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IGBBEFOO_02341 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IGBBEFOO_02342 1.77e-32 yqzJ - - - - - - -
IGBBEFOO_02343 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IGBBEFOO_02344 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
IGBBEFOO_02345 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
IGBBEFOO_02346 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IGBBEFOO_02347 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
IGBBEFOO_02349 2.41e-128 yqjB - - S - - - protein conserved in bacteria
IGBBEFOO_02350 9.33e-226 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
IGBBEFOO_02351 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IGBBEFOO_02352 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IGBBEFOO_02353 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IGBBEFOO_02354 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
IGBBEFOO_02355 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IGBBEFOO_02356 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_02357 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
IGBBEFOO_02358 1.57e-296 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IGBBEFOO_02359 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IGBBEFOO_02360 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IGBBEFOO_02361 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IGBBEFOO_02362 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
IGBBEFOO_02363 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IGBBEFOO_02364 6.35e-201 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
IGBBEFOO_02365 0.0 bkdR - - KT - - - Transcriptional regulator
IGBBEFOO_02366 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
IGBBEFOO_02367 1.07e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IGBBEFOO_02368 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
IGBBEFOO_02369 1.66e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IGBBEFOO_02370 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
IGBBEFOO_02371 7.2e-201 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
IGBBEFOO_02372 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IGBBEFOO_02373 3.68e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IGBBEFOO_02374 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
IGBBEFOO_02375 2.26e-37 - - - - - - - -
IGBBEFOO_02376 1.77e-276 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IGBBEFOO_02378 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IGBBEFOO_02379 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
IGBBEFOO_02380 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IGBBEFOO_02381 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IGBBEFOO_02382 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
IGBBEFOO_02383 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IGBBEFOO_02384 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IGBBEFOO_02385 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IGBBEFOO_02386 2.5e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IGBBEFOO_02387 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IGBBEFOO_02388 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IGBBEFOO_02389 1.65e-88 yqhY - - S - - - protein conserved in bacteria
IGBBEFOO_02390 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IGBBEFOO_02391 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IGBBEFOO_02392 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
IGBBEFOO_02393 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
IGBBEFOO_02394 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
IGBBEFOO_02395 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
IGBBEFOO_02396 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
IGBBEFOO_02397 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
IGBBEFOO_02398 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
IGBBEFOO_02399 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
IGBBEFOO_02400 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
IGBBEFOO_02401 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IGBBEFOO_02402 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IGBBEFOO_02403 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
IGBBEFOO_02404 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
IGBBEFOO_02405 3.79e-223 yqhQ - - S - - - Protein of unknown function (DUF1385)
IGBBEFOO_02406 5.18e-81 yqhP - - - - - - -
IGBBEFOO_02407 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IGBBEFOO_02408 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IGBBEFOO_02409 1.12e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IGBBEFOO_02410 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
IGBBEFOO_02411 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IGBBEFOO_02412 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IGBBEFOO_02413 8.13e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
IGBBEFOO_02414 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IGBBEFOO_02415 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
IGBBEFOO_02416 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
IGBBEFOO_02417 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
IGBBEFOO_02418 1.56e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
IGBBEFOO_02419 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
IGBBEFOO_02420 8.73e-160 yqxM - - - ko:K19433 - ko00000 -
IGBBEFOO_02421 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
IGBBEFOO_02422 4.9e-37 yqzE - - S - - - YqzE-like protein
IGBBEFOO_02423 2.55e-55 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
IGBBEFOO_02424 3.44e-65 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IGBBEFOO_02425 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
IGBBEFOO_02426 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
IGBBEFOO_02427 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
IGBBEFOO_02428 1.29e-220 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
IGBBEFOO_02429 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IGBBEFOO_02431 1.51e-233 yqxL - - P - - - Mg2 transporter protein
IGBBEFOO_02432 8.56e-307 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IGBBEFOO_02433 1.06e-193 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IGBBEFOO_02435 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
IGBBEFOO_02436 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
IGBBEFOO_02437 5.52e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
IGBBEFOO_02438 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
IGBBEFOO_02439 7.34e-66 yqgV - - S - - - Thiamine-binding protein
IGBBEFOO_02440 5.65e-258 yqgU - - - - - - -
IGBBEFOO_02441 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
IGBBEFOO_02442 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IGBBEFOO_02443 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IGBBEFOO_02444 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
IGBBEFOO_02445 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
IGBBEFOO_02446 3.38e-14 yqgO - - - - - - -
IGBBEFOO_02447 2.38e-138 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IGBBEFOO_02448 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IGBBEFOO_02449 1.24e-260 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
IGBBEFOO_02451 3.42e-68 yqzD - - - - - - -
IGBBEFOO_02452 2.92e-98 yqzC - - S - - - YceG-like family
IGBBEFOO_02453 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IGBBEFOO_02454 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IGBBEFOO_02455 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
IGBBEFOO_02456 7.43e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IGBBEFOO_02457 4.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IGBBEFOO_02458 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
IGBBEFOO_02459 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
IGBBEFOO_02460 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
IGBBEFOO_02461 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
IGBBEFOO_02462 9.27e-172 yqgB - - S - - - Protein of unknown function (DUF1189)
IGBBEFOO_02463 2.05e-99 yqgA - - - - - - -
IGBBEFOO_02464 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
IGBBEFOO_02465 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IGBBEFOO_02466 2.04e-81 yqfX - - S - - - membrane
IGBBEFOO_02467 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
IGBBEFOO_02468 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
IGBBEFOO_02469 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IGBBEFOO_02470 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
IGBBEFOO_02471 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IGBBEFOO_02472 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IGBBEFOO_02473 4.89e-58 yqfQ - - S - - - YqfQ-like protein
IGBBEFOO_02474 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IGBBEFOO_02475 2.27e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IGBBEFOO_02476 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IGBBEFOO_02477 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IGBBEFOO_02478 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IGBBEFOO_02479 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IGBBEFOO_02480 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
IGBBEFOO_02481 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IGBBEFOO_02482 3.29e-144 ccpN - - K - - - CBS domain
IGBBEFOO_02483 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IGBBEFOO_02484 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IGBBEFOO_02485 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IGBBEFOO_02486 5.29e-27 - - - S - - - YqzL-like protein
IGBBEFOO_02487 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IGBBEFOO_02488 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IGBBEFOO_02489 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IGBBEFOO_02490 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IGBBEFOO_02491 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
IGBBEFOO_02493 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
IGBBEFOO_02494 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
IGBBEFOO_02495 2.07e-60 yqfC - - S - - - sporulation protein YqfC
IGBBEFOO_02496 3.13e-79 yqfB - - - - - - -
IGBBEFOO_02497 4.35e-192 yqfA - - S - - - UPF0365 protein
IGBBEFOO_02498 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
IGBBEFOO_02499 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
IGBBEFOO_02500 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IGBBEFOO_02501 3.45e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
IGBBEFOO_02502 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
IGBBEFOO_02503 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IGBBEFOO_02504 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
IGBBEFOO_02505 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IGBBEFOO_02506 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IGBBEFOO_02507 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IGBBEFOO_02508 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IGBBEFOO_02509 4.3e-278 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IGBBEFOO_02510 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IGBBEFOO_02511 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
IGBBEFOO_02512 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
IGBBEFOO_02513 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IGBBEFOO_02514 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IGBBEFOO_02515 2.01e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IGBBEFOO_02516 2.36e-22 - - - S - - - YqzM-like protein
IGBBEFOO_02517 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IGBBEFOO_02518 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IGBBEFOO_02519 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
IGBBEFOO_02520 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IGBBEFOO_02521 9.8e-179 yqeM - - Q - - - Methyltransferase
IGBBEFOO_02522 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IGBBEFOO_02523 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
IGBBEFOO_02524 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IGBBEFOO_02525 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
IGBBEFOO_02526 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IGBBEFOO_02527 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IGBBEFOO_02528 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
IGBBEFOO_02530 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
IGBBEFOO_02531 7.45e-180 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IGBBEFOO_02532 3.97e-136 yqeD - - S - - - SNARE associated Golgi protein
IGBBEFOO_02533 7.95e-219 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
IGBBEFOO_02534 9.38e-171 - - - - - - - -
IGBBEFOO_02535 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
IGBBEFOO_02536 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGBBEFOO_02537 0.0 - - - L ko:K06400 - ko00000 Recombinase
IGBBEFOO_02538 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
IGBBEFOO_02539 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
IGBBEFOO_02540 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGBBEFOO_02541 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
IGBBEFOO_02542 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IGBBEFOO_02543 8.68e-120 - - - S - - - Tetratricopeptide repeat
IGBBEFOO_02546 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
IGBBEFOO_02547 1.66e-136 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
IGBBEFOO_02549 5.4e-80 - - - - - - - -
IGBBEFOO_02551 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IGBBEFOO_02552 8.36e-89 - - - S - - - Bacteriophage holin family
IGBBEFOO_02553 2.45e-213 xepA - - - - - - -
IGBBEFOO_02554 9.34e-33 - - - - - - - -
IGBBEFOO_02555 1.01e-73 xkdW - - S - - - XkdW protein
IGBBEFOO_02556 2.91e-283 - - - - - - - -
IGBBEFOO_02557 3e-54 - - - - - - - -
IGBBEFOO_02558 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IGBBEFOO_02559 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IGBBEFOO_02560 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
IGBBEFOO_02561 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
IGBBEFOO_02562 1.02e-231 xkdQ - - G - - - NLP P60 protein
IGBBEFOO_02563 6.56e-156 xkdP - - S - - - Lysin motif
IGBBEFOO_02564 0.0 xkdO - - L - - - Transglycosylase SLT domain
IGBBEFOO_02565 9.14e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IGBBEFOO_02567 4.23e-99 xkdM - - S - - - Phage tail tube protein
IGBBEFOO_02568 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
IGBBEFOO_02569 2.52e-36 - - - - - - - -
IGBBEFOO_02570 3.24e-102 yqbJ - - - - - - -
IGBBEFOO_02571 7.59e-123 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
IGBBEFOO_02572 7.08e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
IGBBEFOO_02573 7.09e-88 - - - S - - - Protein of unknown function (DUF3199)
IGBBEFOO_02574 2.47e-68 - - - S - - - YqbF, hypothetical protein domain
IGBBEFOO_02575 9.21e-216 xkdG - - S - - - Phage capsid family
IGBBEFOO_02576 5.46e-186 yqbD - - L - - - Putative phage serine protease XkdF
IGBBEFOO_02577 2.13e-149 - - - - - - - -
IGBBEFOO_02578 1.73e-217 - - - S - - - Phage Mu protein F like protein
IGBBEFOO_02579 0.0 yqbA - - S - - - portal protein
IGBBEFOO_02580 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
IGBBEFOO_02581 2.02e-158 yqaS - - L - - - DNA packaging
IGBBEFOO_02583 1.58e-105 yqaQ - - L - - - Transposase
IGBBEFOO_02584 7.56e-214 - - - - - - - -
IGBBEFOO_02585 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
IGBBEFOO_02586 1.38e-97 rusA - - L - - - Endodeoxyribonuclease RusA
IGBBEFOO_02588 4.9e-214 yqaM - - L - - - IstB-like ATP binding protein
IGBBEFOO_02589 3.33e-159 yqaL - - L - - - DnaD domain protein
IGBBEFOO_02590 1.1e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
IGBBEFOO_02591 9.38e-229 yqaJ - - L - - - YqaJ-like viral recombinase domain
IGBBEFOO_02595 1.27e-134 - - - - - - - -
IGBBEFOO_02597 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
IGBBEFOO_02598 1.25e-74 - - - K - - - sequence-specific DNA binding
IGBBEFOO_02600 8.73e-132 yqaC - - F - - - adenylate kinase activity
IGBBEFOO_02601 2.25e-131 xkdA - - E - - - IrrE N-terminal-like domain
IGBBEFOO_02602 1.42e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IGBBEFOO_02603 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
IGBBEFOO_02604 7.32e-306 yrkQ - - T - - - Histidine kinase
IGBBEFOO_02605 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
IGBBEFOO_02606 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
IGBBEFOO_02607 1.33e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
IGBBEFOO_02608 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
IGBBEFOO_02609 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
IGBBEFOO_02610 1.21e-170 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
IGBBEFOO_02611 1.11e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
IGBBEFOO_02612 2.1e-272 yrkH - - P - - - Rhodanese Homology Domain
IGBBEFOO_02613 2.04e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
IGBBEFOO_02614 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
IGBBEFOO_02615 4.38e-52 yrkD - - S - - - protein conserved in bacteria
IGBBEFOO_02616 3.81e-139 yrkC - - G - - - Cupin domain
IGBBEFOO_02617 2.15e-195 bltR - - K - - - helix_turn_helix, mercury resistance
IGBBEFOO_02618 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_02619 3.73e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
IGBBEFOO_02620 1.58e-301 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IGBBEFOO_02621 7.28e-25 - - - S - - - YrzO-like protein
IGBBEFOO_02622 1.53e-219 yrdR - - EG - - - EamA-like transporter family
IGBBEFOO_02623 1.2e-204 - - - K - - - Transcriptional regulator
IGBBEFOO_02624 2.58e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
IGBBEFOO_02625 2.26e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
IGBBEFOO_02626 1.75e-87 yodA - - S - - - tautomerase
IGBBEFOO_02627 2.08e-209 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
IGBBEFOO_02629 2.22e-295 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IGBBEFOO_02630 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
IGBBEFOO_02631 2.29e-176 azlC - - E - - - AzlC protein
IGBBEFOO_02632 1.44e-104 bkdR - - K - - - helix_turn_helix ASNC type
IGBBEFOO_02633 1.07e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IGBBEFOO_02634 1.75e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IGBBEFOO_02636 7.37e-133 yrdC - - Q - - - Isochorismatase family
IGBBEFOO_02637 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
IGBBEFOO_02638 1.47e-120 yrdA - - S - - - DinB family
IGBBEFOO_02639 2.66e-215 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
IGBBEFOO_02640 3.79e-249 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IGBBEFOO_02641 8.73e-191 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IGBBEFOO_02642 5.87e-163 yrpD - - S - - - Domain of unknown function, YrpD
IGBBEFOO_02644 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IGBBEFOO_02645 1.1e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IGBBEFOO_02646 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
IGBBEFOO_02647 9.19e-287 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IGBBEFOO_02648 5.13e-211 yraN - - K - - - Transcriptional regulator
IGBBEFOO_02649 7.25e-264 yraM - - S - - - PrpF protein
IGBBEFOO_02651 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IGBBEFOO_02652 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IGBBEFOO_02653 4.9e-200 - - - S - - - Alpha beta hydrolase
IGBBEFOO_02654 6.61e-80 - - - T - - - sh3 domain protein
IGBBEFOO_02655 2.92e-81 - - - T - - - sh3 domain protein
IGBBEFOO_02656 6.62e-87 - - - E - - - Glyoxalase-like domain
IGBBEFOO_02657 4.19e-50 yraG - - - ko:K06440 - ko00000 -
IGBBEFOO_02658 9.61e-84 yraF - - M - - - Spore coat protein
IGBBEFOO_02659 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IGBBEFOO_02660 1.05e-36 yraE - - - ko:K06440 - ko00000 -
IGBBEFOO_02661 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
IGBBEFOO_02662 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
IGBBEFOO_02663 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
IGBBEFOO_02664 4.3e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
IGBBEFOO_02665 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IGBBEFOO_02666 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IGBBEFOO_02667 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IGBBEFOO_02668 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IGBBEFOO_02669 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
IGBBEFOO_02670 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
IGBBEFOO_02671 0.0 levR - - K - - - PTS system fructose IIA component
IGBBEFOO_02672 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IGBBEFOO_02673 5.63e-137 yrhP - - E - - - LysE type translocator
IGBBEFOO_02674 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
IGBBEFOO_02675 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IGBBEFOO_02676 3.67e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
IGBBEFOO_02677 0.0 oatA - - I - - - Acyltransferase family
IGBBEFOO_02678 2.67e-62 yrhK - - S - - - YrhK-like protein
IGBBEFOO_02679 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IGBBEFOO_02680 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
IGBBEFOO_02681 1.1e-126 yrhH - - Q - - - methyltransferase
IGBBEFOO_02682 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
IGBBEFOO_02684 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
IGBBEFOO_02685 1.08e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
IGBBEFOO_02686 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
IGBBEFOO_02687 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
IGBBEFOO_02688 6.93e-49 yrhC - - S - - - YrhC-like protein
IGBBEFOO_02689 4.24e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IGBBEFOO_02690 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
IGBBEFOO_02691 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IGBBEFOO_02692 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
IGBBEFOO_02693 7.27e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
IGBBEFOO_02694 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
IGBBEFOO_02695 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
IGBBEFOO_02696 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IGBBEFOO_02697 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IGBBEFOO_02698 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
IGBBEFOO_02699 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IGBBEFOO_02700 1.7e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
IGBBEFOO_02701 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IGBBEFOO_02702 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
IGBBEFOO_02703 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IGBBEFOO_02704 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
IGBBEFOO_02705 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IGBBEFOO_02706 3.07e-242 yrrI - - S - - - AI-2E family transporter
IGBBEFOO_02707 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IGBBEFOO_02708 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IGBBEFOO_02709 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGBBEFOO_02710 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGBBEFOO_02711 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
IGBBEFOO_02712 8.4e-42 yrzR - - - - - - -
IGBBEFOO_02713 1.23e-108 yrrD - - S - - - protein conserved in bacteria
IGBBEFOO_02714 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IGBBEFOO_02715 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
IGBBEFOO_02716 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IGBBEFOO_02717 2.67e-272 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IGBBEFOO_02718 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_02719 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IGBBEFOO_02720 3.4e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IGBBEFOO_02721 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IGBBEFOO_02722 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IGBBEFOO_02724 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
IGBBEFOO_02725 1.6e-89 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IGBBEFOO_02726 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IGBBEFOO_02727 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IGBBEFOO_02728 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IGBBEFOO_02729 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
IGBBEFOO_02730 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IGBBEFOO_02731 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IGBBEFOO_02732 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
IGBBEFOO_02733 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IGBBEFOO_02734 6.34e-147 yrbG - - S - - - membrane
IGBBEFOO_02735 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
IGBBEFOO_02736 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
IGBBEFOO_02737 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IGBBEFOO_02738 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IGBBEFOO_02739 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
IGBBEFOO_02740 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IGBBEFOO_02741 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IGBBEFOO_02742 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
IGBBEFOO_02743 0.0 csbX - - EGP - - - the major facilitator superfamily
IGBBEFOO_02744 2.77e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
IGBBEFOO_02745 2.32e-152 yrzF - - T - - - serine threonine protein kinase
IGBBEFOO_02747 2.42e-47 - - - S - - - Family of unknown function (DUF5412)
IGBBEFOO_02748 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
IGBBEFOO_02749 8.63e-165 yebC - - K - - - transcriptional regulatory protein
IGBBEFOO_02750 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IGBBEFOO_02751 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
IGBBEFOO_02752 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IGBBEFOO_02753 8.17e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
IGBBEFOO_02754 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
IGBBEFOO_02755 1.27e-294 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IGBBEFOO_02756 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
IGBBEFOO_02757 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IGBBEFOO_02758 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
IGBBEFOO_02759 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IGBBEFOO_02760 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
IGBBEFOO_02761 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IGBBEFOO_02762 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
IGBBEFOO_02763 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IGBBEFOO_02764 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
IGBBEFOO_02765 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IGBBEFOO_02766 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
IGBBEFOO_02767 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IGBBEFOO_02768 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
IGBBEFOO_02769 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IGBBEFOO_02770 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
IGBBEFOO_02771 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IGBBEFOO_02772 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
IGBBEFOO_02773 4.67e-215 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
IGBBEFOO_02774 3.15e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IGBBEFOO_02775 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IGBBEFOO_02776 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IGBBEFOO_02777 1.53e-35 - - - - - - - -
IGBBEFOO_02778 2.91e-253 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IGBBEFOO_02779 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
IGBBEFOO_02780 8.99e-315 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IGBBEFOO_02781 6.39e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
IGBBEFOO_02782 1.57e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IGBBEFOO_02783 2.66e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IGBBEFOO_02784 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
IGBBEFOO_02785 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IGBBEFOO_02786 8.23e-117 ysxD - - - - - - -
IGBBEFOO_02787 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IGBBEFOO_02788 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IGBBEFOO_02789 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
IGBBEFOO_02790 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IGBBEFOO_02791 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IGBBEFOO_02792 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
IGBBEFOO_02793 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IGBBEFOO_02794 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IGBBEFOO_02795 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IGBBEFOO_02796 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IGBBEFOO_02797 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IGBBEFOO_02798 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IGBBEFOO_02799 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IGBBEFOO_02801 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
IGBBEFOO_02802 1.01e-184 ysnF - - S - - - protein conserved in bacteria
IGBBEFOO_02804 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IGBBEFOO_02805 1.06e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IGBBEFOO_02806 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IGBBEFOO_02807 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
IGBBEFOO_02808 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IGBBEFOO_02809 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGBBEFOO_02810 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_02811 1.6e-103 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
IGBBEFOO_02812 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IGBBEFOO_02813 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IGBBEFOO_02814 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
IGBBEFOO_02815 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
IGBBEFOO_02816 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IGBBEFOO_02817 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IGBBEFOO_02818 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IGBBEFOO_02819 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
IGBBEFOO_02821 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
IGBBEFOO_02822 1.28e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
IGBBEFOO_02823 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
IGBBEFOO_02824 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_02825 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IGBBEFOO_02826 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
IGBBEFOO_02827 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IGBBEFOO_02828 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
IGBBEFOO_02829 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
IGBBEFOO_02830 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IGBBEFOO_02831 6.77e-219 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGBBEFOO_02832 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IGBBEFOO_02833 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IGBBEFOO_02834 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGBBEFOO_02835 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
IGBBEFOO_02836 6.71e-265 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
IGBBEFOO_02837 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
IGBBEFOO_02838 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
IGBBEFOO_02839 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
IGBBEFOO_02841 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
IGBBEFOO_02842 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
IGBBEFOO_02843 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
IGBBEFOO_02844 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IGBBEFOO_02845 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IGBBEFOO_02846 1.47e-288 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IGBBEFOO_02847 1.05e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
IGBBEFOO_02848 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IGBBEFOO_02849 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
IGBBEFOO_02850 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
IGBBEFOO_02851 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IGBBEFOO_02852 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
IGBBEFOO_02853 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
IGBBEFOO_02854 1.27e-59 ysdA - - S - - - Membrane
IGBBEFOO_02855 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IGBBEFOO_02856 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IGBBEFOO_02857 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IGBBEFOO_02859 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IGBBEFOO_02860 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IGBBEFOO_02861 2.9e-168 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
IGBBEFOO_02862 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_02863 2.07e-191 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
IGBBEFOO_02864 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IGBBEFOO_02865 5.98e-206 ytxC - - S - - - YtxC-like family
IGBBEFOO_02866 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
IGBBEFOO_02867 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IGBBEFOO_02868 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
IGBBEFOO_02869 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IGBBEFOO_02870 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IGBBEFOO_02871 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IGBBEFOO_02872 9.85e-88 ytcD - - K - - - Transcriptional regulator
IGBBEFOO_02873 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
IGBBEFOO_02874 4.54e-205 ytbE - - S - - - reductase
IGBBEFOO_02875 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IGBBEFOO_02876 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
IGBBEFOO_02877 7e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IGBBEFOO_02878 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IGBBEFOO_02879 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
IGBBEFOO_02880 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_02881 2.55e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
IGBBEFOO_02882 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
IGBBEFOO_02883 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IGBBEFOO_02884 9.38e-95 ytwI - - S - - - membrane
IGBBEFOO_02885 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
IGBBEFOO_02886 5.68e-83 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
IGBBEFOO_02887 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IGBBEFOO_02888 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IGBBEFOO_02889 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IGBBEFOO_02890 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IGBBEFOO_02891 6.01e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IGBBEFOO_02892 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IGBBEFOO_02893 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
IGBBEFOO_02894 5.12e-112 ytrI - - - - - - -
IGBBEFOO_02895 1.15e-39 - - - - - - - -
IGBBEFOO_02896 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
IGBBEFOO_02897 2.15e-63 ytpI - - S - - - YtpI-like protein
IGBBEFOO_02898 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
IGBBEFOO_02899 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
IGBBEFOO_02900 2.09e-306 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IGBBEFOO_02901 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
IGBBEFOO_02902 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IGBBEFOO_02903 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
IGBBEFOO_02904 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IGBBEFOO_02905 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IGBBEFOO_02906 4.08e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGBBEFOO_02907 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGBBEFOO_02908 4.01e-194 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IGBBEFOO_02909 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IGBBEFOO_02910 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IGBBEFOO_02911 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
IGBBEFOO_02912 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
IGBBEFOO_02913 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_02915 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IGBBEFOO_02916 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IGBBEFOO_02917 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
IGBBEFOO_02918 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGBBEFOO_02919 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
IGBBEFOO_02920 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IGBBEFOO_02921 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
IGBBEFOO_02922 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
IGBBEFOO_02923 7.05e-113 yteJ - - S - - - RDD family
IGBBEFOO_02924 6.13e-233 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
IGBBEFOO_02925 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IGBBEFOO_02926 0.0 ytcJ - - S - - - amidohydrolase
IGBBEFOO_02927 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IGBBEFOO_02928 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IGBBEFOO_02929 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IGBBEFOO_02930 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IGBBEFOO_02931 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IGBBEFOO_02932 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IGBBEFOO_02933 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IGBBEFOO_02934 2.94e-142 yttP - - K - - - Transcriptional regulator
IGBBEFOO_02935 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IGBBEFOO_02936 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
IGBBEFOO_02937 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IGBBEFOO_02939 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IGBBEFOO_02940 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IGBBEFOO_02941 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IGBBEFOO_02942 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IGBBEFOO_02943 6.51e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
IGBBEFOO_02944 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IGBBEFOO_02945 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IGBBEFOO_02946 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IGBBEFOO_02947 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IGBBEFOO_02948 1.9e-72 ytxJ - - O - - - Protein of unknown function (DUF2847)
IGBBEFOO_02949 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
IGBBEFOO_02950 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IGBBEFOO_02951 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IGBBEFOO_02952 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IGBBEFOO_02953 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IGBBEFOO_02954 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
IGBBEFOO_02955 3.17e-75 ytpP - - CO - - - Thioredoxin
IGBBEFOO_02956 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
IGBBEFOO_02957 2.24e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
IGBBEFOO_02958 4.06e-68 ytzB - - S - - - small secreted protein
IGBBEFOO_02959 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IGBBEFOO_02960 2.16e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IGBBEFOO_02961 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IGBBEFOO_02962 9.51e-61 ytzH - - S - - - YtzH-like protein
IGBBEFOO_02963 3.02e-192 ytmP - - M - - - Phosphotransferase
IGBBEFOO_02964 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
IGBBEFOO_02965 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IGBBEFOO_02966 4.92e-212 ytlQ - - - - - - -
IGBBEFOO_02967 7.71e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IGBBEFOO_02968 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IGBBEFOO_02969 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
IGBBEFOO_02970 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
IGBBEFOO_02971 8.45e-263 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
IGBBEFOO_02972 2.4e-169 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IGBBEFOO_02973 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
IGBBEFOO_02974 9.04e-171 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IGBBEFOO_02975 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IGBBEFOO_02976 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
IGBBEFOO_02977 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
IGBBEFOO_02978 2.14e-36 yteV - - S - - - Sporulation protein Cse60
IGBBEFOO_02979 1.97e-152 yteU - - S - - - Integral membrane protein
IGBBEFOO_02980 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
IGBBEFOO_02981 5.81e-95 yteS - - G - - - transport
IGBBEFOO_02982 2.23e-286 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IGBBEFOO_02983 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
IGBBEFOO_02984 0.0 ytdP - - K - - - Transcriptional regulator
IGBBEFOO_02985 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IGBBEFOO_02986 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IGBBEFOO_02987 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
IGBBEFOO_02988 2.64e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IGBBEFOO_02989 4.57e-244 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IGBBEFOO_02990 5.04e-164 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IGBBEFOO_02991 3.73e-284 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IGBBEFOO_02992 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IGBBEFOO_02993 4.04e-182 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IGBBEFOO_02994 1.43e-222 - - - S - - - Acetyl xylan esterase (AXE1)
IGBBEFOO_02995 1.12e-244 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_02996 4.68e-315 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IGBBEFOO_02997 2.86e-215 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGBBEFOO_02998 1.32e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IGBBEFOO_02999 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IGBBEFOO_03000 1.22e-68 ytwF - - P - - - Sulfurtransferase
IGBBEFOO_03001 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IGBBEFOO_03002 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
IGBBEFOO_03003 6.61e-184 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IGBBEFOO_03004 2.98e-269 yttB - - EGP - - - Major facilitator superfamily
IGBBEFOO_03005 2.02e-78 yttA - - S - - - Pfam Transposase IS66
IGBBEFOO_03006 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
IGBBEFOO_03007 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_03008 1.58e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
IGBBEFOO_03009 1.77e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_03010 5.92e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IGBBEFOO_03011 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_03012 1.07e-189 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
IGBBEFOO_03013 3.35e-222 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IGBBEFOO_03014 1.03e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_03015 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
IGBBEFOO_03017 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
IGBBEFOO_03018 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
IGBBEFOO_03019 6.76e-137 ytqB - - J - - - Putative rRNA methylase
IGBBEFOO_03020 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
IGBBEFOO_03021 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
IGBBEFOO_03022 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IGBBEFOO_03023 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IGBBEFOO_03024 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IGBBEFOO_03025 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IGBBEFOO_03026 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IGBBEFOO_03027 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
IGBBEFOO_03028 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IGBBEFOO_03029 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IGBBEFOO_03030 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IGBBEFOO_03031 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IGBBEFOO_03032 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IGBBEFOO_03033 1.59e-81 ytkC - - S - - - Bacteriophage holin family
IGBBEFOO_03034 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IGBBEFOO_03036 8.26e-96 ytkA - - S - - - YtkA-like
IGBBEFOO_03037 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IGBBEFOO_03038 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IGBBEFOO_03039 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IGBBEFOO_03040 2.81e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IGBBEFOO_03041 2.96e-241 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IGBBEFOO_03042 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
IGBBEFOO_03043 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IGBBEFOO_03044 1.64e-299 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IGBBEFOO_03045 1.83e-180 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IGBBEFOO_03046 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IGBBEFOO_03047 1.22e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IGBBEFOO_03048 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IGBBEFOO_03049 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IGBBEFOO_03050 5.09e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IGBBEFOO_03051 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IGBBEFOO_03052 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IGBBEFOO_03053 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
IGBBEFOO_03054 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
IGBBEFOO_03055 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IGBBEFOO_03056 7.74e-231 ytcB - - M - - - NAD-dependent epimerase dehydratase
IGBBEFOO_03057 3.7e-300 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
IGBBEFOO_03059 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
IGBBEFOO_03060 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
IGBBEFOO_03061 9.43e-263 cotI - - S ko:K06331 - ko00000 Spore coat protein
IGBBEFOO_03062 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
IGBBEFOO_03063 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IGBBEFOO_03064 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
IGBBEFOO_03065 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
IGBBEFOO_03066 2.96e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IGBBEFOO_03067 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IGBBEFOO_03089 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IGBBEFOO_03090 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
IGBBEFOO_03091 1.2e-122 - - - M - - - FR47-like protein
IGBBEFOO_03092 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
IGBBEFOO_03093 4.06e-110 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
IGBBEFOO_03094 1.95e-109 yuaE - - S - - - DinB superfamily
IGBBEFOO_03095 8.58e-139 yuaD - - - - - - -
IGBBEFOO_03096 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IGBBEFOO_03097 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IGBBEFOO_03098 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
IGBBEFOO_03099 5.83e-118 yuaB - - - - - - -
IGBBEFOO_03100 1.83e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IGBBEFOO_03101 1.85e-301 - - - P ko:K03498 - ko00000,ko02000 Potassium
IGBBEFOO_03102 3.31e-52 yubF - - S - - - yiaA/B two helix domain
IGBBEFOO_03103 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IGBBEFOO_03104 0.0 yubD - - P - - - Major Facilitator Superfamily
IGBBEFOO_03105 6.82e-114 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
IGBBEFOO_03107 6.02e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IGBBEFOO_03108 3.8e-256 yubA - - S - - - transporter activity
IGBBEFOO_03109 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IGBBEFOO_03110 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
IGBBEFOO_03111 4.94e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
IGBBEFOO_03112 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IGBBEFOO_03113 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IGBBEFOO_03114 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
IGBBEFOO_03115 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IGBBEFOO_03116 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IGBBEFOO_03117 6.34e-300 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IGBBEFOO_03118 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IGBBEFOO_03119 1.06e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IGBBEFOO_03120 5e-48 - - - - - - - -
IGBBEFOO_03121 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
IGBBEFOO_03122 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IGBBEFOO_03123 1.07e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IGBBEFOO_03124 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
IGBBEFOO_03125 1.35e-51 - - - - - - - -
IGBBEFOO_03126 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
IGBBEFOO_03127 1.76e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
IGBBEFOO_03128 4.22e-95 yugN - - S - - - YugN-like family
IGBBEFOO_03130 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IGBBEFOO_03131 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
IGBBEFOO_03132 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
IGBBEFOO_03133 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
IGBBEFOO_03134 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IGBBEFOO_03135 6.62e-256 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
IGBBEFOO_03136 6.74e-112 alaR - - K - - - Transcriptional regulator
IGBBEFOO_03137 1.2e-201 yugF - - I - - - Hydrolase
IGBBEFOO_03138 6.7e-56 yugE - - S - - - Domain of unknown function (DUF1871)
IGBBEFOO_03139 2.09e-289 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IGBBEFOO_03140 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_03141 4.3e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
IGBBEFOO_03142 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
IGBBEFOO_03144 1.96e-245 yuxJ - - EGP - - - Major facilitator superfamily
IGBBEFOO_03145 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
IGBBEFOO_03146 3.31e-98 yuxK - - S - - - protein conserved in bacteria
IGBBEFOO_03147 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
IGBBEFOO_03148 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IGBBEFOO_03149 1.14e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IGBBEFOO_03150 6.34e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
IGBBEFOO_03151 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_03152 1.57e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IGBBEFOO_03153 1.47e-216 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IGBBEFOO_03154 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
IGBBEFOO_03155 7.06e-22 - - - - - - - -
IGBBEFOO_03156 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IGBBEFOO_03157 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IGBBEFOO_03158 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IGBBEFOO_03159 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IGBBEFOO_03160 7.39e-103 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IGBBEFOO_03161 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IGBBEFOO_03162 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
IGBBEFOO_03163 3.18e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
IGBBEFOO_03164 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IGBBEFOO_03165 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_03167 1.4e-209 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
IGBBEFOO_03168 6.29e-10 - - - S - - - DegQ (SacQ) family
IGBBEFOO_03169 9.63e-08 - - - - - - - -
IGBBEFOO_03170 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
IGBBEFOO_03171 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IGBBEFOO_03172 5.65e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
IGBBEFOO_03173 1.32e-88 - - - S - - - Protein of unknown function (DUF1694)
IGBBEFOO_03174 1.63e-52 yueH - - S - - - YueH-like protein
IGBBEFOO_03175 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
IGBBEFOO_03176 4.72e-245 yueF - - S - - - transporter activity
IGBBEFOO_03177 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
IGBBEFOO_03178 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
IGBBEFOO_03179 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
IGBBEFOO_03180 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_03181 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
IGBBEFOO_03182 0.0 yueB - - S - - - type VII secretion protein EsaA
IGBBEFOO_03183 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IGBBEFOO_03184 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
IGBBEFOO_03185 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
IGBBEFOO_03186 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
IGBBEFOO_03187 1.03e-292 yukF - - QT - - - Transcriptional regulator
IGBBEFOO_03188 4.9e-263 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
IGBBEFOO_03189 2.07e-169 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
IGBBEFOO_03190 1.42e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
IGBBEFOO_03191 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGBBEFOO_03192 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
IGBBEFOO_03193 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
IGBBEFOO_03194 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IGBBEFOO_03195 1.43e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_03196 1.55e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
IGBBEFOO_03197 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
IGBBEFOO_03198 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
IGBBEFOO_03199 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
IGBBEFOO_03200 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IGBBEFOO_03201 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
IGBBEFOO_03202 1.69e-151 yuiC - - S - - - protein conserved in bacteria
IGBBEFOO_03203 9.78e-47 yuiB - - S - - - Putative membrane protein
IGBBEFOO_03204 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IGBBEFOO_03205 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
IGBBEFOO_03207 1.15e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IGBBEFOO_03208 2.96e-151 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
IGBBEFOO_03209 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IGBBEFOO_03210 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
IGBBEFOO_03211 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IGBBEFOO_03212 1.54e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IGBBEFOO_03213 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
IGBBEFOO_03214 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IGBBEFOO_03215 6.61e-75 yuzD - - S - - - protein conserved in bacteria
IGBBEFOO_03216 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
IGBBEFOO_03217 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
IGBBEFOO_03218 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IGBBEFOO_03219 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IGBBEFOO_03220 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IGBBEFOO_03221 4.63e-255 yutH - - S - - - Spore coat protein
IGBBEFOO_03222 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IGBBEFOO_03223 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IGBBEFOO_03224 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
IGBBEFOO_03225 3.2e-63 yutD - - S - - - protein conserved in bacteria
IGBBEFOO_03226 9.45e-145 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IGBBEFOO_03227 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IGBBEFOO_03228 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
IGBBEFOO_03229 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
IGBBEFOO_03230 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
IGBBEFOO_03231 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IGBBEFOO_03232 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
IGBBEFOO_03233 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
IGBBEFOO_03234 2.72e-82 yunG - - - - - - -
IGBBEFOO_03235 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IGBBEFOO_03236 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
IGBBEFOO_03237 1.46e-300 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
IGBBEFOO_03238 1.65e-285 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
IGBBEFOO_03239 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IGBBEFOO_03240 1.41e-79 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IGBBEFOO_03241 1.3e-126 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IGBBEFOO_03242 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IGBBEFOO_03243 4.85e-194 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IGBBEFOO_03244 2.62e-144 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
IGBBEFOO_03245 5.12e-243 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IGBBEFOO_03247 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IGBBEFOO_03248 4.9e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IGBBEFOO_03249 6.53e-218 bsn - - L - - - Ribonuclease
IGBBEFOO_03250 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGBBEFOO_03251 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IGBBEFOO_03252 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
IGBBEFOO_03253 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IGBBEFOO_03254 1.24e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IGBBEFOO_03255 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IGBBEFOO_03256 2.24e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IGBBEFOO_03257 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
IGBBEFOO_03258 1.42e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
IGBBEFOO_03260 3.35e-56 - - - - - - - -
IGBBEFOO_03261 2.14e-87 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGBBEFOO_03262 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
IGBBEFOO_03263 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
IGBBEFOO_03264 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IGBBEFOO_03265 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
IGBBEFOO_03266 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IGBBEFOO_03267 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IGBBEFOO_03268 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
IGBBEFOO_03269 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
IGBBEFOO_03270 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IGBBEFOO_03271 3.6e-73 yusD - - S - - - SCP-2 sterol transfer family
IGBBEFOO_03272 2e-73 yusE - - CO - - - Thioredoxin
IGBBEFOO_03273 1.32e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
IGBBEFOO_03274 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
IGBBEFOO_03275 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IGBBEFOO_03276 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IGBBEFOO_03277 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IGBBEFOO_03278 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
IGBBEFOO_03279 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
IGBBEFOO_03280 2.86e-14 - - - S - - - YuzL-like protein
IGBBEFOO_03281 2.09e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IGBBEFOO_03282 2.23e-54 - - - - - - - -
IGBBEFOO_03283 2.12e-70 yusN - - M - - - Coat F domain
IGBBEFOO_03284 3.83e-99 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
IGBBEFOO_03285 0.0 yusP - - P - - - Major facilitator superfamily
IGBBEFOO_03286 1.76e-86 yusQ - - S - - - Tautomerase enzyme
IGBBEFOO_03287 6.81e-82 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_03288 4.48e-67 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_03289 1.52e-206 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
IGBBEFOO_03290 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
IGBBEFOO_03291 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IGBBEFOO_03292 2.01e-87 - - - S - - - YusW-like protein
IGBBEFOO_03293 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
IGBBEFOO_03294 1.21e-41 pepF2 - - E - - - COG1164 Oligoendopeptidase F
IGBBEFOO_03295 6.65e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_03296 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
IGBBEFOO_03297 9.63e-306 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IGBBEFOO_03298 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_03299 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_03300 3.06e-204 yuxN - - K - - - Transcriptional regulator
IGBBEFOO_03301 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IGBBEFOO_03302 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
IGBBEFOO_03303 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IGBBEFOO_03304 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IGBBEFOO_03305 1.22e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
IGBBEFOO_03306 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IGBBEFOO_03307 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_03308 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
IGBBEFOO_03309 6.57e-178 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IGBBEFOO_03310 4.22e-144 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IGBBEFOO_03311 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
IGBBEFOO_03312 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_03313 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
IGBBEFOO_03314 0.0 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IGBBEFOO_03315 3.29e-237 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_03316 5.15e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IGBBEFOO_03317 5.21e-182 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_03318 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
IGBBEFOO_03319 0.0 yvrG - - T - - - Histidine kinase
IGBBEFOO_03320 2.08e-169 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_03321 5.07e-32 - - - - - - - -
IGBBEFOO_03322 6.74e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
IGBBEFOO_03323 3.46e-26 - - - S - - - YvrJ protein family
IGBBEFOO_03324 1.59e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IGBBEFOO_03325 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
IGBBEFOO_03326 1.17e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IGBBEFOO_03327 1.62e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_03328 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
IGBBEFOO_03329 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IGBBEFOO_03330 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_03331 1.48e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGBBEFOO_03332 1.14e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGBBEFOO_03334 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
IGBBEFOO_03335 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
IGBBEFOO_03336 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
IGBBEFOO_03337 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
IGBBEFOO_03338 5.58e-218 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
IGBBEFOO_03339 6.57e-179 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
IGBBEFOO_03340 6.08e-154 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
IGBBEFOO_03341 4.54e-203 yvgN - - S - - - reductase
IGBBEFOO_03342 7.97e-113 yvgO - - - - - - -
IGBBEFOO_03343 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
IGBBEFOO_03344 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IGBBEFOO_03345 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IGBBEFOO_03346 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IGBBEFOO_03347 3.88e-140 yvgT - - S - - - membrane
IGBBEFOO_03348 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
IGBBEFOO_03349 3.45e-137 bdbD - - O - - - Thioredoxin
IGBBEFOO_03350 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IGBBEFOO_03351 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IGBBEFOO_03352 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
IGBBEFOO_03353 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
IGBBEFOO_03354 7.89e-254 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IGBBEFOO_03355 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IGBBEFOO_03356 0.0 - - - S - - - Fusaric acid resistance protein-like
IGBBEFOO_03357 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
IGBBEFOO_03358 4.28e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IGBBEFOO_03359 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
IGBBEFOO_03360 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_03362 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IGBBEFOO_03363 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IGBBEFOO_03364 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
IGBBEFOO_03365 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
IGBBEFOO_03366 4.03e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
IGBBEFOO_03367 3.44e-48 yvzC - - K - - - transcriptional
IGBBEFOO_03368 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
IGBBEFOO_03369 1.19e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IGBBEFOO_03370 3.85e-72 yvaP - - K - - - transcriptional
IGBBEFOO_03371 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IGBBEFOO_03372 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IGBBEFOO_03373 2.89e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IGBBEFOO_03374 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IGBBEFOO_03375 6.29e-272 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IGBBEFOO_03376 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IGBBEFOO_03377 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
IGBBEFOO_03378 4.79e-224 - - - - - - - -
IGBBEFOO_03380 8.32e-133 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IGBBEFOO_03381 9.63e-60 sdpR - - K - - - transcriptional
IGBBEFOO_03382 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IGBBEFOO_03383 2.58e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IGBBEFOO_03384 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IGBBEFOO_03385 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IGBBEFOO_03386 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IGBBEFOO_03387 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
IGBBEFOO_03388 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
IGBBEFOO_03389 2.38e-158 yvbI - - M - - - Membrane
IGBBEFOO_03390 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IGBBEFOO_03391 2.4e-106 yvbK - - K - - - acetyltransferase
IGBBEFOO_03392 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IGBBEFOO_03393 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
IGBBEFOO_03394 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IGBBEFOO_03395 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IGBBEFOO_03396 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IGBBEFOO_03397 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IGBBEFOO_03398 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IGBBEFOO_03399 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
IGBBEFOO_03400 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IGBBEFOO_03401 3.45e-206 yvbU - - K - - - Transcriptional regulator
IGBBEFOO_03402 2.37e-199 yvbV - - EG - - - EamA-like transporter family
IGBBEFOO_03403 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IGBBEFOO_03404 2.68e-252 - - - S - - - Glycosyl hydrolase
IGBBEFOO_03405 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IGBBEFOO_03406 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IGBBEFOO_03407 5.47e-176 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IGBBEFOO_03408 7.53e-137 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IGBBEFOO_03409 1.76e-257 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_03410 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IGBBEFOO_03411 1.03e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IGBBEFOO_03412 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
IGBBEFOO_03413 1.52e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
IGBBEFOO_03414 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
IGBBEFOO_03415 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
IGBBEFOO_03416 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IGBBEFOO_03417 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IGBBEFOO_03418 2.05e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IGBBEFOO_03419 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_03420 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
IGBBEFOO_03421 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IGBBEFOO_03422 2.57e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IGBBEFOO_03423 5.69e-44 yvfG - - S - - - YvfG protein
IGBBEFOO_03424 1.85e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
IGBBEFOO_03425 1.2e-284 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IGBBEFOO_03426 6.53e-81 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IGBBEFOO_03427 1.65e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IGBBEFOO_03428 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IGBBEFOO_03429 4.44e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IGBBEFOO_03430 5.09e-264 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
IGBBEFOO_03431 6.3e-251 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IGBBEFOO_03432 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
IGBBEFOO_03433 7.49e-280 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IGBBEFOO_03434 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
IGBBEFOO_03435 2.95e-286 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
IGBBEFOO_03436 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IGBBEFOO_03437 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IGBBEFOO_03438 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
IGBBEFOO_03439 2.15e-99 - - - K ko:K19417 - ko00000,ko03000 transcriptional
IGBBEFOO_03440 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
IGBBEFOO_03442 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
IGBBEFOO_03443 5.1e-64 - - - S - - - Protein of unknown function (DUF3237)
IGBBEFOO_03444 1.51e-163 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IGBBEFOO_03445 0.0 pbpE - - V - - - Beta-lactamase
IGBBEFOO_03446 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
IGBBEFOO_03447 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IGBBEFOO_03448 0.0 ybeC - - E - - - amino acid
IGBBEFOO_03449 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
IGBBEFOO_03450 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IGBBEFOO_03451 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
IGBBEFOO_03452 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
IGBBEFOO_03453 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
IGBBEFOO_03454 1.99e-235 - - - S - - - Patatin-like phospholipase
IGBBEFOO_03456 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IGBBEFOO_03457 1.01e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IGBBEFOO_03458 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IGBBEFOO_03459 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
IGBBEFOO_03460 2.42e-203 malA - - S - - - Protein of unknown function (DUF1189)
IGBBEFOO_03461 1.18e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IGBBEFOO_03462 2.12e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IGBBEFOO_03463 1.03e-302 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IGBBEFOO_03464 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
IGBBEFOO_03465 2.28e-223 yvdE - - K - - - Transcriptional regulator
IGBBEFOO_03466 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IGBBEFOO_03467 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
IGBBEFOO_03468 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IGBBEFOO_03469 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IGBBEFOO_03470 1.4e-235 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGBBEFOO_03471 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
IGBBEFOO_03472 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_03473 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
IGBBEFOO_03474 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_03475 1.37e-45 - - - - - - - -
IGBBEFOO_03476 5.24e-188 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
IGBBEFOO_03477 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
IGBBEFOO_03478 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IGBBEFOO_03479 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IGBBEFOO_03480 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IGBBEFOO_03481 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IGBBEFOO_03482 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IGBBEFOO_03483 3.05e-190 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
IGBBEFOO_03484 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
IGBBEFOO_03485 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IGBBEFOO_03487 0.0 - - - - - - - -
IGBBEFOO_03488 6.36e-172 - - - - - - - -
IGBBEFOO_03489 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
IGBBEFOO_03490 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IGBBEFOO_03491 1.44e-170 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IGBBEFOO_03492 7.21e-150 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IGBBEFOO_03493 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IGBBEFOO_03494 1.19e-297 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IGBBEFOO_03495 9.09e-149 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IGBBEFOO_03496 2.07e-282 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IGBBEFOO_03497 2.14e-179 yvpB - - NU - - - protein conserved in bacteria
IGBBEFOO_03498 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
IGBBEFOO_03499 5.29e-121 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IGBBEFOO_03500 4.51e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IGBBEFOO_03501 3.19e-212 yvoD - - P - - - COG0370 Fe2 transport system protein B
IGBBEFOO_03502 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IGBBEFOO_03503 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IGBBEFOO_03504 2.25e-284 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IGBBEFOO_03505 1.39e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IGBBEFOO_03506 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
IGBBEFOO_03507 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
IGBBEFOO_03508 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGBBEFOO_03509 1.61e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IGBBEFOO_03510 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
IGBBEFOO_03511 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGBBEFOO_03512 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
IGBBEFOO_03513 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
IGBBEFOO_03514 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
IGBBEFOO_03515 5.8e-221 yvlB - - S - - - Putative adhesin
IGBBEFOO_03516 8.09e-65 yvlA - - - - - - -
IGBBEFOO_03517 2.73e-46 yvkN - - - - - - -
IGBBEFOO_03518 2.57e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IGBBEFOO_03519 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IGBBEFOO_03520 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IGBBEFOO_03521 2.54e-42 csbA - - S - - - protein conserved in bacteria
IGBBEFOO_03522 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
IGBBEFOO_03523 1.43e-131 yvkB - - K - - - Transcriptional regulator
IGBBEFOO_03524 5.47e-298 yvkA - - P - - - -transporter
IGBBEFOO_03525 3.86e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IGBBEFOO_03526 1.38e-73 swrA - - S - - - Swarming motility protein
IGBBEFOO_03527 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IGBBEFOO_03528 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IGBBEFOO_03529 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
IGBBEFOO_03530 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IGBBEFOO_03531 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IGBBEFOO_03532 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IGBBEFOO_03533 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IGBBEFOO_03534 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IGBBEFOO_03535 9.14e-88 - - - - - - - -
IGBBEFOO_03536 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
IGBBEFOO_03537 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
IGBBEFOO_03538 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IGBBEFOO_03539 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
IGBBEFOO_03540 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IGBBEFOO_03541 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IGBBEFOO_03542 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IGBBEFOO_03543 4.19e-93 yviE - - - - - - -
IGBBEFOO_03544 1.97e-199 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
IGBBEFOO_03545 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
IGBBEFOO_03546 3.5e-102 yvyG - - NOU - - - FlgN protein
IGBBEFOO_03547 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
IGBBEFOO_03548 1.83e-96 yvyF - - S - - - flagellar protein
IGBBEFOO_03549 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
IGBBEFOO_03550 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
IGBBEFOO_03551 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IGBBEFOO_03552 2.15e-199 degV - - S - - - protein conserved in bacteria
IGBBEFOO_03553 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IGBBEFOO_03554 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IGBBEFOO_03555 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
IGBBEFOO_03556 3.99e-225 yvhJ - - K - - - Transcriptional regulator
IGBBEFOO_03557 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IGBBEFOO_03558 3.3e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
IGBBEFOO_03559 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IGBBEFOO_03560 6.04e-149 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
IGBBEFOO_03561 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
IGBBEFOO_03562 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IGBBEFOO_03563 8.77e-283 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
IGBBEFOO_03564 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IGBBEFOO_03565 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IGBBEFOO_03566 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IGBBEFOO_03567 0.0 lytB - - D - - - Stage II sporulation protein
IGBBEFOO_03568 3.26e-50 - - - - - - - -
IGBBEFOO_03569 2.77e-219 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IGBBEFOO_03570 6.61e-278 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IGBBEFOO_03571 1.78e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IGBBEFOO_03572 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IGBBEFOO_03573 0.0 - - - M - - - Glycosyltransferase like family 2
IGBBEFOO_03574 5.43e-05 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
IGBBEFOO_03575 2.13e-127 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IGBBEFOO_03576 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IGBBEFOO_03577 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IGBBEFOO_03578 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IGBBEFOO_03579 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
IGBBEFOO_03580 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
IGBBEFOO_03581 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IGBBEFOO_03582 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IGBBEFOO_03583 0.0 - - - - - - - -
IGBBEFOO_03584 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IGBBEFOO_03585 1.16e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IGBBEFOO_03586 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IGBBEFOO_03587 1.24e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IGBBEFOO_03588 2.29e-275 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
IGBBEFOO_03589 8.19e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IGBBEFOO_03590 1.48e-222 ywtF_2 - - K - - - Transcriptional regulator
IGBBEFOO_03591 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IGBBEFOO_03592 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IGBBEFOO_03593 2.29e-29 ywtC - - - - - - -
IGBBEFOO_03594 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IGBBEFOO_03595 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
IGBBEFOO_03596 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
IGBBEFOO_03597 2.3e-228 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
IGBBEFOO_03598 6.44e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGBBEFOO_03599 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IGBBEFOO_03600 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IGBBEFOO_03601 2.87e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IGBBEFOO_03602 1.34e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
IGBBEFOO_03603 2.49e-122 batE - - T - - - Sh3 type 3 domain protein
IGBBEFOO_03604 9.2e-64 ywsA - - S - - - Protein of unknown function (DUF3892)
IGBBEFOO_03605 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
IGBBEFOO_03606 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IGBBEFOO_03607 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IGBBEFOO_03608 3.36e-218 alsR - - K - - - LysR substrate binding domain
IGBBEFOO_03609 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IGBBEFOO_03610 9.09e-164 ywrJ - - - - - - -
IGBBEFOO_03611 1.02e-196 cotB - - - ko:K06325 - ko00000 -
IGBBEFOO_03612 1.12e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
IGBBEFOO_03613 2.17e-16 - - - - - - - -
IGBBEFOO_03614 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IGBBEFOO_03615 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
IGBBEFOO_03616 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IGBBEFOO_03617 4.83e-108 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IGBBEFOO_03618 5.52e-133 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
IGBBEFOO_03619 3.66e-115 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
IGBBEFOO_03621 3.83e-132 ywqN - - S - - - NAD(P)H-dependent
IGBBEFOO_03622 1.16e-209 - - - K - - - Transcriptional regulator
IGBBEFOO_03623 7.78e-176 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IGBBEFOO_03624 1.36e-71 - - - S - - - MORN repeat variant
IGBBEFOO_03625 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
IGBBEFOO_03626 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
IGBBEFOO_03628 2.52e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
IGBBEFOO_03629 9.82e-315 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IGBBEFOO_03630 3.16e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
IGBBEFOO_03631 4.51e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IGBBEFOO_03632 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
IGBBEFOO_03633 3.6e-25 - - - - - - - -
IGBBEFOO_03634 0.0 ywqB - - S - - - SWIM zinc finger
IGBBEFOO_03635 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IGBBEFOO_03636 4.53e-203 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IGBBEFOO_03637 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IGBBEFOO_03638 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
IGBBEFOO_03639 5.26e-88 ywpG - - - - - - -
IGBBEFOO_03640 8.81e-89 ywpF - - S - - - YwpF-like protein
IGBBEFOO_03641 4.63e-68 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
IGBBEFOO_03642 8.54e-198 ywpD - - T - - - Histidine kinase
IGBBEFOO_03643 1.13e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IGBBEFOO_03644 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IGBBEFOO_03645 5.45e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
IGBBEFOO_03646 4.1e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IGBBEFOO_03647 6.18e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IGBBEFOO_03648 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
IGBBEFOO_03649 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
IGBBEFOO_03650 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
IGBBEFOO_03651 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_03652 1.02e-312 ywoF - - P - - - Right handed beta helix region
IGBBEFOO_03653 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
IGBBEFOO_03654 8e-309 ywoD - - EGP - - - Major facilitator superfamily
IGBBEFOO_03655 2.56e-134 yjgF - - Q - - - Isochorismatase family
IGBBEFOO_03656 3.04e-102 - - - - - - - -
IGBBEFOO_03657 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
IGBBEFOO_03658 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
IGBBEFOO_03659 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
IGBBEFOO_03660 1.63e-95 ywnJ - - S - - - VanZ like family
IGBBEFOO_03661 2.13e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IGBBEFOO_03662 1.55e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
IGBBEFOO_03663 3.28e-22 ywnC - - S - - - Family of unknown function (DUF5362)
IGBBEFOO_03664 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
IGBBEFOO_03665 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGBBEFOO_03666 3.41e-184 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
IGBBEFOO_03667 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
IGBBEFOO_03668 1.29e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
IGBBEFOO_03669 4.58e-85 ywnA - - K - - - Transcriptional regulator
IGBBEFOO_03670 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IGBBEFOO_03671 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
IGBBEFOO_03672 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
IGBBEFOO_03674 1.11e-21 csbD - - K - - - CsbD-like
IGBBEFOO_03675 1.12e-109 ywmF - - S - - - Peptidase M50
IGBBEFOO_03676 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IGBBEFOO_03677 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IGBBEFOO_03678 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IGBBEFOO_03680 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IGBBEFOO_03681 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IGBBEFOO_03682 3.72e-238 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
IGBBEFOO_03683 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IGBBEFOO_03684 2.39e-174 ywmB - - S - - - TATA-box binding
IGBBEFOO_03685 4.54e-45 ywzB - - S - - - membrane
IGBBEFOO_03686 6.12e-115 ywmA - - - - - - -
IGBBEFOO_03687 1.04e-76 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IGBBEFOO_03688 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IGBBEFOO_03689 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IGBBEFOO_03690 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IGBBEFOO_03691 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IGBBEFOO_03692 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IGBBEFOO_03693 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IGBBEFOO_03694 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IGBBEFOO_03695 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
IGBBEFOO_03696 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IGBBEFOO_03697 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IGBBEFOO_03698 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
IGBBEFOO_03699 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
IGBBEFOO_03700 5.75e-103 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IGBBEFOO_03701 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
IGBBEFOO_03702 4.44e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IGBBEFOO_03703 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
IGBBEFOO_03704 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
IGBBEFOO_03705 1.67e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IGBBEFOO_03707 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IGBBEFOO_03708 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IGBBEFOO_03709 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGBBEFOO_03710 6.26e-119 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IGBBEFOO_03711 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IGBBEFOO_03712 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IGBBEFOO_03713 8.53e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IGBBEFOO_03714 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
IGBBEFOO_03715 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IGBBEFOO_03716 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
IGBBEFOO_03717 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IGBBEFOO_03718 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IGBBEFOO_03719 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
IGBBEFOO_03720 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
IGBBEFOO_03721 3.31e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
IGBBEFOO_03722 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IGBBEFOO_03723 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IGBBEFOO_03724 2.1e-269 acdA - - I - - - acyl-CoA dehydrogenase
IGBBEFOO_03725 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
IGBBEFOO_03726 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IGBBEFOO_03727 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IGBBEFOO_03728 1.32e-57 ywjC - - - - - - -
IGBBEFOO_03729 1.35e-124 ywjB - - H - - - RibD C-terminal domain
IGBBEFOO_03730 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IGBBEFOO_03731 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGBBEFOO_03732 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
IGBBEFOO_03733 6.32e-128 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
IGBBEFOO_03734 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
IGBBEFOO_03735 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IGBBEFOO_03736 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
IGBBEFOO_03737 1.57e-180 ywiC - - S - - - YwiC-like protein
IGBBEFOO_03738 3.98e-169 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
IGBBEFOO_03739 3.39e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IGBBEFOO_03740 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IGBBEFOO_03741 4.64e-96 ywiB - - S - - - protein conserved in bacteria
IGBBEFOO_03742 3.71e-12 - - - S - - - Bacteriocin subtilosin A
IGBBEFOO_03743 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
IGBBEFOO_03745 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IGBBEFOO_03746 1.07e-300 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
IGBBEFOO_03747 7.55e-280 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
IGBBEFOO_03748 0.0 - - - L - - - Peptidase, M16
IGBBEFOO_03750 0.0 ywhL - - CO - - - amine dehydrogenase activity
IGBBEFOO_03751 2.36e-291 ywhK - - CO - - - amine dehydrogenase activity
IGBBEFOO_03752 2.88e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IGBBEFOO_03754 6.61e-110 - - - S - - - Aminoacyl-tRNA editing domain
IGBBEFOO_03755 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IGBBEFOO_03756 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IGBBEFOO_03757 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IGBBEFOO_03758 1.92e-123 ywhD - - S - - - YwhD family
IGBBEFOO_03759 3.29e-154 ywhC - - S - - - Peptidase family M50
IGBBEFOO_03760 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
IGBBEFOO_03761 1.76e-94 ywhA - - K - - - Transcriptional regulator
IGBBEFOO_03762 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IGBBEFOO_03764 2.66e-307 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
IGBBEFOO_03765 1.1e-103 yffB - - K - - - Transcriptional regulator
IGBBEFOO_03766 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
IGBBEFOO_03767 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
IGBBEFOO_03768 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
IGBBEFOO_03769 5.65e-147 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
IGBBEFOO_03770 1.57e-204 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
IGBBEFOO_03771 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IGBBEFOO_03772 9.56e-212 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_03773 7.1e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
IGBBEFOO_03774 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
IGBBEFOO_03775 3.52e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
IGBBEFOO_03776 1.89e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
IGBBEFOO_03777 1.36e-268 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IGBBEFOO_03778 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IGBBEFOO_03779 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGBBEFOO_03780 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IGBBEFOO_03781 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IGBBEFOO_03782 1.89e-275 ywfA - - EGP - - - -transporter
IGBBEFOO_03783 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IGBBEFOO_03784 0.0 rocB - - E - - - arginine degradation protein
IGBBEFOO_03785 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IGBBEFOO_03786 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IGBBEFOO_03787 1.1e-102 - - - - - - - -
IGBBEFOO_03788 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
IGBBEFOO_03789 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IGBBEFOO_03790 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IGBBEFOO_03791 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IGBBEFOO_03792 2.54e-243 spsG - - M - - - Spore Coat
IGBBEFOO_03793 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
IGBBEFOO_03794 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
IGBBEFOO_03795 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
IGBBEFOO_03796 4.54e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IGBBEFOO_03797 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
IGBBEFOO_03798 4.87e-188 spsA - - M - - - Spore Coat
IGBBEFOO_03799 7.61e-114 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IGBBEFOO_03800 1.59e-78 ywdK - - S - - - small membrane protein
IGBBEFOO_03801 4.57e-304 ywdJ - - F - - - Xanthine uracil
IGBBEFOO_03802 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
IGBBEFOO_03803 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IGBBEFOO_03804 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IGBBEFOO_03805 5.69e-193 ywdF - - S - - - Glycosyltransferase like family 2
IGBBEFOO_03807 8.74e-146 ywdD - - - - - - -
IGBBEFOO_03808 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
IGBBEFOO_03809 5.43e-188 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IGBBEFOO_03810 6.19e-39 ywdA - - - - - - -
IGBBEFOO_03811 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IGBBEFOO_03812 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_03813 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
IGBBEFOO_03814 4.49e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IGBBEFOO_03816 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IGBBEFOO_03817 4.19e-239 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IGBBEFOO_03818 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
IGBBEFOO_03819 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IGBBEFOO_03820 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
IGBBEFOO_03821 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IGBBEFOO_03822 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IGBBEFOO_03823 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IGBBEFOO_03824 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IGBBEFOO_03825 5.11e-49 ydaS - - S - - - membrane
IGBBEFOO_03826 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IGBBEFOO_03827 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IGBBEFOO_03828 3.33e-77 gtcA - - S - - - GtrA-like protein
IGBBEFOO_03829 4.16e-159 ywcC - - K - - - transcriptional regulator
IGBBEFOO_03831 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
IGBBEFOO_03832 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IGBBEFOO_03833 1.08e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IGBBEFOO_03834 3.23e-310 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
IGBBEFOO_03835 6.21e-249 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
IGBBEFOO_03836 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
IGBBEFOO_03837 7.69e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IGBBEFOO_03838 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IGBBEFOO_03839 2.7e-203 ywbI - - K - - - Transcriptional regulator
IGBBEFOO_03840 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IGBBEFOO_03841 1.21e-143 ywbG - - M - - - effector of murein hydrolase
IGBBEFOO_03842 1.29e-280 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
IGBBEFOO_03843 1.32e-39 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
IGBBEFOO_03844 1.3e-283 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
IGBBEFOO_03845 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
IGBBEFOO_03846 7.78e-165 ywbB - - S - - - Protein of unknown function (DUF2711)
IGBBEFOO_03847 9.36e-317 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGBBEFOO_03848 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IGBBEFOO_03849 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_03850 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IGBBEFOO_03851 6.53e-217 gspA - - M - - - General stress
IGBBEFOO_03852 3.96e-164 ywaF - - S - - - Integral membrane protein
IGBBEFOO_03853 2.15e-115 ywaE - - K - - - Transcriptional regulator
IGBBEFOO_03854 2.7e-298 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IGBBEFOO_03855 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
IGBBEFOO_03856 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
IGBBEFOO_03857 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
IGBBEFOO_03858 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
IGBBEFOO_03859 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGBBEFOO_03860 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
IGBBEFOO_03861 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGBBEFOO_03862 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IGBBEFOO_03863 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_03864 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IGBBEFOO_03865 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IGBBEFOO_03866 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_03867 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGBBEFOO_03868 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
IGBBEFOO_03869 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IGBBEFOO_03870 8.94e-28 yxzF - - - - - - -
IGBBEFOO_03871 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IGBBEFOO_03872 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IGBBEFOO_03873 4.48e-277 yxlH - - EGP - - - Major Facilitator Superfamily
IGBBEFOO_03874 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IGBBEFOO_03875 6e-213 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_03876 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
IGBBEFOO_03877 1.75e-43 - - - - - - - -
IGBBEFOO_03878 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
IGBBEFOO_03879 9.06e-125 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IGBBEFOO_03880 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
IGBBEFOO_03881 2.01e-206 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IGBBEFOO_03882 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
IGBBEFOO_03883 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
IGBBEFOO_03884 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
IGBBEFOO_03885 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IGBBEFOO_03886 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
IGBBEFOO_03887 0.0 - - - O - - - Peptidase family M48
IGBBEFOO_03889 1.58e-200 yxkH - - G - - - Polysaccharide deacetylase
IGBBEFOO_03890 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IGBBEFOO_03891 1.16e-211 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
IGBBEFOO_03892 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IGBBEFOO_03893 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IGBBEFOO_03894 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
IGBBEFOO_03895 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IGBBEFOO_03896 2.01e-123 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
IGBBEFOO_03897 1.53e-213 - - - K - - - LysR substrate binding domain
IGBBEFOO_03898 5.63e-102 - - - S - - - Protein of unknown function (DUF1453)
IGBBEFOO_03899 7.13e-261 - - - T - - - Signal transduction histidine kinase
IGBBEFOO_03900 5.66e-150 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
IGBBEFOO_03901 7.76e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IGBBEFOO_03904 2.57e-114 yxjI - - S - - - LURP-one-related
IGBBEFOO_03905 7.74e-280 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IGBBEFOO_03906 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IGBBEFOO_03907 5.83e-176 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IGBBEFOO_03908 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IGBBEFOO_03909 4.65e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IGBBEFOO_03910 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
IGBBEFOO_03911 4.55e-206 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
IGBBEFOO_03912 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IGBBEFOO_03913 2.96e-29 - - - T - - - Domain of unknown function (DUF4163)
IGBBEFOO_03914 9.65e-65 yxiS - - - - - - -
IGBBEFOO_03915 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IGBBEFOO_03916 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IGBBEFOO_03917 2.62e-185 bglS - - M - - - licheninase activity
IGBBEFOO_03918 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IGBBEFOO_03919 2.75e-145 - - - - - - - -
IGBBEFOO_03920 3.97e-294 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
IGBBEFOO_03921 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IGBBEFOO_03922 3.28e-279 - - - E - - - GDSL-like Lipase/Acylhydrolase
IGBBEFOO_03925 5.53e-65 yxiJ - - S - - - YxiJ-like protein
IGBBEFOO_03926 3.79e-125 yxiI - - S - - - Protein of unknown function (DUF2716)
IGBBEFOO_03927 6.22e-107 - - - - - - - -
IGBBEFOO_03928 1.2e-57 - - - - - - - -
IGBBEFOO_03929 8.76e-99 yxiG - - - - - - -
IGBBEFOO_03930 1.12e-82 - - - - - - - -
IGBBEFOO_03931 3.69e-111 - - - - - - - -
IGBBEFOO_03932 1.09e-94 yxxG - - - - - - -
IGBBEFOO_03933 0.0 wapA - - M - - - COG3209 Rhs family protein
IGBBEFOO_03934 1.17e-216 yxxF - - EG - - - EamA-like transporter family
IGBBEFOO_03935 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
IGBBEFOO_03936 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IGBBEFOO_03937 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_03938 1.33e-67 - - - - - - - -
IGBBEFOO_03939 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
IGBBEFOO_03940 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
IGBBEFOO_03941 2.3e-53 yxiC - - S - - - Family of unknown function (DUF5344)
IGBBEFOO_03942 1.88e-37 - - - S - - - Domain of unknown function (DUF5082)
IGBBEFOO_03943 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IGBBEFOO_03944 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IGBBEFOO_03945 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
IGBBEFOO_03946 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IGBBEFOO_03947 2.44e-303 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
IGBBEFOO_03948 4.15e-232 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IGBBEFOO_03949 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IGBBEFOO_03950 4.9e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
IGBBEFOO_03951 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IGBBEFOO_03952 1.44e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IGBBEFOO_03953 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IGBBEFOO_03954 9.11e-198 - - - S - - - Domain of Unknown Function (DUF1206)
IGBBEFOO_03955 4.86e-259 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
IGBBEFOO_03956 0.0 yxeQ - - S - - - MmgE/PrpD family
IGBBEFOO_03957 5.21e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IGBBEFOO_03958 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_03959 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IGBBEFOO_03960 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IGBBEFOO_03961 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IGBBEFOO_03962 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IGBBEFOO_03964 2.17e-243 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IGBBEFOO_03965 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
IGBBEFOO_03968 7.32e-42 yxeE - - - - - - -
IGBBEFOO_03969 2.66e-28 yxeD - - - - - - -
IGBBEFOO_03970 6.79e-91 - - - - - - - -
IGBBEFOO_03971 9.01e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGBBEFOO_03972 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
IGBBEFOO_03973 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IGBBEFOO_03974 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IGBBEFOO_03975 4e-233 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_03976 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_03977 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IGBBEFOO_03978 9.32e-188 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IGBBEFOO_03979 1.87e-213 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
IGBBEFOO_03980 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IGBBEFOO_03981 1.46e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
IGBBEFOO_03982 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IGBBEFOO_03983 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IGBBEFOO_03984 2.13e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IGBBEFOO_03985 1.46e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IGBBEFOO_03986 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IGBBEFOO_03987 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IGBBEFOO_03988 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
IGBBEFOO_03990 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
IGBBEFOO_03991 1.77e-314 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IGBBEFOO_03992 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
IGBBEFOO_03994 4.33e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IGBBEFOO_03995 3.66e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
IGBBEFOO_03996 1.21e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IGBBEFOO_03997 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
IGBBEFOO_03998 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
IGBBEFOO_03999 1.29e-177 yxbB - - Q - - - Met-10+ like-protein
IGBBEFOO_04000 3.65e-59 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
IGBBEFOO_04001 8.99e-114 yxnB - - - - - - -
IGBBEFOO_04002 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IGBBEFOO_04003 1.8e-271 yxaM - - U - - - MFS_1 like family
IGBBEFOO_04004 2.63e-137 yxaL - - S - - - PQQ-like domain
IGBBEFOO_04005 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
IGBBEFOO_04006 2.83e-99 yxaI - - S - - - membrane protein domain
IGBBEFOO_04007 2.88e-290 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
IGBBEFOO_04008 9.33e-254 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
IGBBEFOO_04009 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IGBBEFOO_04010 4.48e-257 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IGBBEFOO_04011 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IGBBEFOO_04012 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
IGBBEFOO_04013 2.19e-153 yxaC - - M - - - effector of murein hydrolase
IGBBEFOO_04014 1.79e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
IGBBEFOO_04015 2.54e-267 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IGBBEFOO_04016 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
IGBBEFOO_04017 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IGBBEFOO_04018 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IGBBEFOO_04019 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IGBBEFOO_04020 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
IGBBEFOO_04021 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
IGBBEFOO_04022 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IGBBEFOO_04023 1.2e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IGBBEFOO_04024 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
IGBBEFOO_04025 1.44e-24 - - - - - - - -
IGBBEFOO_04026 4.04e-154 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IGBBEFOO_04027 5.06e-144 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IGBBEFOO_04028 1.55e-173 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
IGBBEFOO_04029 1.35e-237 - - - S - - - Radical SAM superfamily
IGBBEFOO_04030 1.99e-17 - - - - - - - -
IGBBEFOO_04031 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
IGBBEFOO_04032 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
IGBBEFOO_04033 7.17e-86 - - - - - - - -
IGBBEFOO_04034 0.0 - - - S - - - Calcineurin-like phosphoesterase
IGBBEFOO_04035 1.23e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IGBBEFOO_04037 1.25e-93 - - - - - - - -
IGBBEFOO_04038 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IGBBEFOO_04040 1.7e-45 yycQ - - S - - - Protein of unknown function (DUF2651)
IGBBEFOO_04041 1.77e-281 yycP - - - - - - -
IGBBEFOO_04042 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IGBBEFOO_04043 3.84e-113 yycN - - K - - - Acetyltransferase
IGBBEFOO_04044 3.03e-239 - - - S - - - aspartate phosphatase
IGBBEFOO_04046 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IGBBEFOO_04047 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IGBBEFOO_04048 1.5e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
IGBBEFOO_04049 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IGBBEFOO_04050 2.42e-281 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IGBBEFOO_04051 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IGBBEFOO_04052 1.2e-200 yycI - - S - - - protein conserved in bacteria
IGBBEFOO_04053 0.0 yycH - - S - - - protein conserved in bacteria
IGBBEFOO_04054 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IGBBEFOO_04055 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IGBBEFOO_04060 6.38e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IGBBEFOO_04061 1.19e-101 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGBBEFOO_04062 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IGBBEFOO_04063 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IGBBEFOO_04065 1.89e-22 yycC - - K - - - YycC-like protein
IGBBEFOO_04066 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
IGBBEFOO_04067 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IGBBEFOO_04068 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IGBBEFOO_04069 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IGBBEFOO_04070 5.23e-205 yybS - - S - - - membrane
IGBBEFOO_04072 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
IGBBEFOO_04073 6.68e-90 yybR - - K - - - Transcriptional regulator
IGBBEFOO_04074 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
IGBBEFOO_04075 2.34e-92 - - - - - - - -
IGBBEFOO_04077 6.8e-308 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_04078 3.44e-22 - - - - - - - -
IGBBEFOO_04079 1.61e-102 yybN - - S - - - Protein of unknown function (DUF2712)
IGBBEFOO_04080 3.78e-169 - - - - - - - -
IGBBEFOO_04081 5.36e-157 - - - - - - - -
IGBBEFOO_04082 2.34e-163 - - - S - - - Protein of unknown function (DUF2705)
IGBBEFOO_04083 1.14e-149 yybJ - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IGBBEFOO_04084 4.35e-194 - - - - - - - -
IGBBEFOO_04085 3.02e-88 - - - S - - - SnoaL-like domain
IGBBEFOO_04086 1.46e-164 yybG - - S - - - Pentapeptide repeat-containing protein
IGBBEFOO_04087 3.31e-281 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_04088 1.36e-212 yybE - - K - - - Transcriptional regulator
IGBBEFOO_04089 7.91e-104 yjcF - - S - - - Acetyltransferase (GNAT) domain
IGBBEFOO_04090 1.27e-99 yybC - - - - - - -
IGBBEFOO_04091 5.29e-165 - - - S - - - Metallo-beta-lactamase superfamily
IGBBEFOO_04092 4.54e-100 yybA - - K - - - transcriptional
IGBBEFOO_04093 2.45e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
IGBBEFOO_04094 8.73e-132 yyaS - - S ko:K07149 - ko00000 Membrane
IGBBEFOO_04095 4.03e-130 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
IGBBEFOO_04096 1.09e-87 - - - S - - - YjbR
IGBBEFOO_04097 2.2e-139 yyaP - - H - - - RibD C-terminal domain
IGBBEFOO_04098 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
IGBBEFOO_04099 1.46e-58 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
IGBBEFOO_04100 1.34e-88 - - - K - - - MerR HTH family regulatory protein
IGBBEFOO_04101 1.99e-207 - - - EG - - - EamA-like transporter family
IGBBEFOO_04102 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IGBBEFOO_04103 8.91e-217 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
IGBBEFOO_04104 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
IGBBEFOO_04105 1.14e-130 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
IGBBEFOO_04106 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGBBEFOO_04107 3.03e-230 ccpB - - K - - - Transcriptional regulator
IGBBEFOO_04108 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IGBBEFOO_04109 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IGBBEFOO_04110 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IGBBEFOO_04111 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IGBBEFOO_04112 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IGBBEFOO_04113 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IGBBEFOO_04114 7.41e-45 yyzM - - S - - - protein conserved in bacteria
IGBBEFOO_04115 5.34e-227 yyaD - - S - - - Membrane
IGBBEFOO_04116 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
IGBBEFOO_04117 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IGBBEFOO_04118 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
IGBBEFOO_04119 1.13e-98 - - - S - - - Bacterial PH domain
IGBBEFOO_04120 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IGBBEFOO_04121 8.68e-169 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IGBBEFOO_04122 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IGBBEFOO_04123 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IGBBEFOO_04124 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
IGBBEFOO_04125 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IGBBEFOO_04126 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IGBBEFOO_04127 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IGBBEFOO_04128 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IGBBEFOO_04129 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
IGBBEFOO_04130 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IGBBEFOO_04131 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
IGBBEFOO_04132 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGBBEFOO_04133 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGBBEFOO_04134 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IGBBEFOO_04137 4.5e-234 yaaC - - S - - - YaaC-like Protein
IGBBEFOO_04138 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IGBBEFOO_04139 2.81e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IGBBEFOO_04140 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IGBBEFOO_04141 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IGBBEFOO_04142 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IGBBEFOO_04144 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
IGBBEFOO_04145 2.43e-150 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
IGBBEFOO_04146 7.7e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
IGBBEFOO_04147 1.44e-127 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
IGBBEFOO_04148 1.55e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IGBBEFOO_04149 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGBBEFOO_04150 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IGBBEFOO_04151 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IGBBEFOO_04152 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
IGBBEFOO_04153 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
IGBBEFOO_04154 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IGBBEFOO_04157 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
IGBBEFOO_04158 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IGBBEFOO_04159 5.05e-260 yaaN - - P - - - Belongs to the TelA family
IGBBEFOO_04160 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
IGBBEFOO_04161 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IGBBEFOO_04162 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
IGBBEFOO_04163 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
IGBBEFOO_04164 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IGBBEFOO_04165 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
IGBBEFOO_04166 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
IGBBEFOO_04167 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
IGBBEFOO_04168 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
IGBBEFOO_04169 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IGBBEFOO_04170 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
IGBBEFOO_04171 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IGBBEFOO_04172 5.05e-185 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
IGBBEFOO_04173 1.91e-283 yabE - - T - - - protein conserved in bacteria
IGBBEFOO_04174 1.05e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IGBBEFOO_04175 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IGBBEFOO_04176 6.69e-200 yabG - - S ko:K06436 - ko00000 peptidase
IGBBEFOO_04177 5.32e-53 veg - - S - - - protein conserved in bacteria
IGBBEFOO_04178 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
IGBBEFOO_04179 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IGBBEFOO_04180 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IGBBEFOO_04181 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
IGBBEFOO_04182 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IGBBEFOO_04183 9e-310 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IGBBEFOO_04184 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGBBEFOO_04185 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IGBBEFOO_04186 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IGBBEFOO_04187 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
IGBBEFOO_04188 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IGBBEFOO_04189 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
IGBBEFOO_04190 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IGBBEFOO_04191 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IGBBEFOO_04192 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IGBBEFOO_04193 1.91e-66 yabP - - S - - - Sporulation protein YabP
IGBBEFOO_04194 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
IGBBEFOO_04195 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IGBBEFOO_04196 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IGBBEFOO_04199 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
IGBBEFOO_04200 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IGBBEFOO_04201 1.25e-238 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
IGBBEFOO_04202 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IGBBEFOO_04203 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
IGBBEFOO_04204 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IGBBEFOO_04205 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IGBBEFOO_04206 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IGBBEFOO_04207 6.68e-196 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
IGBBEFOO_04208 3.77e-218 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IGBBEFOO_04209 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IGBBEFOO_04210 1.03e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
IGBBEFOO_04211 2.27e-216 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
IGBBEFOO_04212 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IGBBEFOO_04213 2.78e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IGBBEFOO_04214 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IGBBEFOO_04215 1.81e-41 yazB - - K - - - transcriptional
IGBBEFOO_04216 7.88e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGBBEFOO_04217 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IGBBEFOO_04218 7.91e-96 - - - S - - - domain protein
IGBBEFOO_04219 1.14e-239 - - - S - - - Phage tail protein
IGBBEFOO_04220 9.69e-159 - - - S - - - peptidoglycan catabolic process
IGBBEFOO_04222 2.65e-85 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
IGBBEFOO_04227 4.09e-153 - - - M - - - Glycosyl hydrolases family 25
IGBBEFOO_04228 7.4e-122 - - - S - - - Phage integrase family
IGBBEFOO_04229 6.81e-242 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
IGBBEFOO_04230 7.45e-82 - - - S - - - Immunity protein 70
IGBBEFOO_04232 4.9e-78 - - - - - - - -
IGBBEFOO_04233 7.94e-28 - - - L - - - COG3666 Transposase and inactivated derivatives
IGBBEFOO_04234 1.58e-164 - - - - - - - -
IGBBEFOO_04242 1.37e-70 - - - L - - - Domain of unknown function (DUF1738)
IGBBEFOO_04243 6.66e-181 - - - S - - - DNA gyrase/topoisomerase IV, subunit A
IGBBEFOO_04244 1.41e-229 - - - S - - - DNA gyrase B
IGBBEFOO_04245 5.92e-17 - - - S - - - Replication initiator protein A (RepA) N-terminus
IGBBEFOO_04254 1.57e-17 - - - F - - - Guanylate kinase homologues.
IGBBEFOO_04258 0.0 - - - S - - - Bacterial DNA polymerase III alpha subunit
IGBBEFOO_04262 4.61e-60 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGBBEFOO_04268 1.77e-14 M1-624 - - K - - - Transcriptional regulator
IGBBEFOO_04269 1.32e-100 - - - S - - - exonuclease activity
IGBBEFOO_04271 2.38e-111 - - - S - - - DNA primase activity
IGBBEFOO_04272 1.09e-132 - - - S - - - DNA helicase activity
IGBBEFOO_04273 1.21e-11 - - - - - - - -
IGBBEFOO_04276 2.45e-51 - - - - - - - -
IGBBEFOO_04279 1.3e-130 - - - S - - - Ribonucleotide reductase, small chain
IGBBEFOO_04280 0.0 - - - S - - - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
IGBBEFOO_04281 2.72e-80 - - - S - - - AAA domain
IGBBEFOO_04284 2.56e-62 - - - F - - - Nucleoside 2-deoxyribosyltransferase
IGBBEFOO_04288 6.29e-43 yxcD - - S - - - Protein of unknown function (DUF2653)
IGBBEFOO_04290 5.79e-19 - - - - - - - -
IGBBEFOO_04291 1.23e-52 - - - S ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphoribosyl-ATP pyrophosphohydrolase
IGBBEFOO_04295 7.94e-94 - - - L - - - integrase family
IGBBEFOO_04298 4.22e-23 - - - S - - - 3D domain
IGBBEFOO_04299 2.33e-67 - - - S - - - DNA ligase (ATP) activity
IGBBEFOO_04301 2.05e-103 - - - - - - - -
IGBBEFOO_04303 2e-225 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IGBBEFOO_04306 0.000166 - - - L - - - Phage terminase small Subunit
IGBBEFOO_04309 6.42e-132 - - - S - - - Phage portal protein
IGBBEFOO_04310 3.46e-64 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
IGBBEFOO_04311 1.58e-108 - - - S - - - Phage capsid family
IGBBEFOO_04313 1.9e-05 - - - S - - - Phage gp6-like head-tail connector protein
IGBBEFOO_04317 2.66e-52 - - - S - - - Phage tail tube protein
IGBBEFOO_04321 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
IGBBEFOO_04322 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
IGBBEFOO_04323 1.04e-122 gerD - - - ko:K06294 - ko00000 -
IGBBEFOO_04324 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IGBBEFOO_04325 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IGBBEFOO_04326 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
IGBBEFOO_04327 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
IGBBEFOO_04328 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IGBBEFOO_04329 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IGBBEFOO_04330 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IGBBEFOO_04331 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGBBEFOO_04332 1.1e-194 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGBBEFOO_04333 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGBBEFOO_04334 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IGBBEFOO_04335 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGBBEFOO_04336 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IGBBEFOO_04337 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IGBBEFOO_04338 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IGBBEFOO_04339 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IGBBEFOO_04340 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IGBBEFOO_04341 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IGBBEFOO_04342 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IGBBEFOO_04343 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IGBBEFOO_04344 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IGBBEFOO_04345 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IGBBEFOO_04346 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IGBBEFOO_04347 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IGBBEFOO_04348 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IGBBEFOO_04349 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGBBEFOO_04350 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IGBBEFOO_04351 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IGBBEFOO_04352 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IGBBEFOO_04353 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IGBBEFOO_04354 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IGBBEFOO_04355 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IGBBEFOO_04356 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IGBBEFOO_04357 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IGBBEFOO_04358 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IGBBEFOO_04359 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IGBBEFOO_04360 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IGBBEFOO_04361 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IGBBEFOO_04362 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IGBBEFOO_04363 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IGBBEFOO_04364 8.78e-238 ybaC - - S - - - Alpha/beta hydrolase family
IGBBEFOO_04365 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IGBBEFOO_04366 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IGBBEFOO_04367 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IGBBEFOO_04368 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IGBBEFOO_04369 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
IGBBEFOO_04370 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGBBEFOO_04371 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGBBEFOO_04372 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IGBBEFOO_04373 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IGBBEFOO_04374 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IGBBEFOO_04375 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IGBBEFOO_04376 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IGBBEFOO_04377 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IGBBEFOO_04378 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IGBBEFOO_04379 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
IGBBEFOO_04380 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
IGBBEFOO_04381 4.29e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGBBEFOO_04382 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IGBBEFOO_04383 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IGBBEFOO_04384 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
IGBBEFOO_04385 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IGBBEFOO_04386 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IGBBEFOO_04387 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IGBBEFOO_04388 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
IGBBEFOO_04389 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IGBBEFOO_04390 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IGBBEFOO_04391 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
IGBBEFOO_04392 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IGBBEFOO_04393 2.76e-65 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
IGBBEFOO_04394 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IGBBEFOO_04395 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)