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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NPANDNHF_00013	2.43e-85	-	-	-	-	-	-	-	-
NPANDNHF_00014	5.3e-28	-	-	-	-	-	-	-	-
NPANDNHF_00017	5.29e-32	-	-	-	L	-	-	-	N-terminal phage replisome organiser (Phage_rep_org_N)
NPANDNHF_00018	1.18e-65	-	-	-	S	-	-	-	Putative HNHc nuclease
NPANDNHF_00023	4.71e-100	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
NPANDNHF_00024	2.84e-18	-	-	-	S	-	-	-	sequence-specific DNA binding
NPANDNHF_00026	1.82e-55	XK27_10050	-	-	K	-	-	-	sequence-specific DNA binding
NPANDNHF_00027	7.8e-74	-	-	-	D	-	-	-	T5orf172
NPANDNHF_00031	4.24e-98	-	-	-	K	-	-	-	SIR2-like domain
NPANDNHF_00032	6.24e-24	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
NPANDNHF_00034	1.87e-106	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPANDNHF_00035	4.51e-88	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPANDNHF_00036	2.08e-121	-	-	-	EG	-	-	-	EamA-like transporter family
NPANDNHF_00037	4.84e-102	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
NPANDNHF_00038	4.89e-142	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
NPANDNHF_00039	3.98e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NPANDNHF_00041	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPANDNHF_00042	1.36e-287	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NPANDNHF_00043	3.19e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NPANDNHF_00044	4.07e-77	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
NPANDNHF_00045	1.16e-191	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPANDNHF_00046	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPANDNHF_00047	2.75e-222	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NPANDNHF_00048	4.37e-276	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPANDNHF_00050	6.69e-115	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NPANDNHF_00051	4.63e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPANDNHF_00052	5.92e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NPANDNHF_00053	2.42e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPANDNHF_00054	1.19e-195	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NPANDNHF_00055	4.22e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
NPANDNHF_00056	5.08e-112	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NPANDNHF_00057	4.64e-31	-	-	-	M	-	-	-	Lysin motif
NPANDNHF_00058	1.85e-155	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NPANDNHF_00059	9.37e-81	-	-	-	S	-	-	-	Helix-turn-helix domain
NPANDNHF_00060	3.6e-276	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NPANDNHF_00061	5.37e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPANDNHF_00062	2.2e-264	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPANDNHF_00063	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NPANDNHF_00064	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NPANDNHF_00065	1.88e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPANDNHF_00066	2.12e-87	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPANDNHF_00067	8.4e-131	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NPANDNHF_00068	3.29e-167	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPANDNHF_00069	4.01e-121	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NPANDNHF_00070	2.05e-137	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NPANDNHF_00071	1.51e-255	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NPANDNHF_00072	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NPANDNHF_00074	1.24e-102	-	-	-	F	-	-	-	Hydrolase, nudix family
NPANDNHF_00075	4.41e-72	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
NPANDNHF_00076	1.34e-86	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NPANDNHF_00077	1.38e-92	-	-	-	M	-	-	-	GNAT acetyltransferase
NPANDNHF_00079	2.27e-243	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
NPANDNHF_00080	5.59e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NPANDNHF_00081	5.33e-237	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NPANDNHF_00082	5.8e-99	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPANDNHF_00083	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NPANDNHF_00084	1.7e-143	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NPANDNHF_00085	8.77e-159	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NPANDNHF_00086	1.16e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
NPANDNHF_00087	6.23e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPANDNHF_00088	1.14e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NPANDNHF_00089	3.83e-79	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPANDNHF_00090	1.96e-75	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPANDNHF_00091	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPANDNHF_00092	6.04e-275	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPANDNHF_00093	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPANDNHF_00094	3.63e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
NPANDNHF_00095	8.99e-225	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NPANDNHF_00096	1.68e-125	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NPANDNHF_00097	6.37e-88	-	-	-	-	-	-	-	-
NPANDNHF_00100	6.13e-21	-	-	-	-	-	-	-	-
NPANDNHF_00101	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NPANDNHF_00102	5.42e-38	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NPANDNHF_00103	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NPANDNHF_00111	1.48e-82	-	-	-	H	-	-	-	Methyltransferase domain
NPANDNHF_00112	1.79e-92	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
NPANDNHF_00113	1.58e-51	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
NPANDNHF_00115	3.89e-31	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
NPANDNHF_00117	6.99e-33	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
NPANDNHF_00118	2.05e-40	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
NPANDNHF_00119	1.98e-42	-	-	-	S	-	-	-	CHY zinc finger
NPANDNHF_00120	1.26e-53	ywnA	-	-	K	-	-	-	Transcriptional regulator
NPANDNHF_00121	2.79e-105	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
NPANDNHF_00123	3.29e-55	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NPANDNHF_00124	1.13e-223	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NPANDNHF_00125	1.17e-81	-	-	-	-	-	-	-	-
NPANDNHF_00126	7.47e-104	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NPANDNHF_00127	3.53e-144	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NPANDNHF_00128	1.51e-75	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NPANDNHF_00129	3.28e-239	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPANDNHF_00130	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NPANDNHF_00131	9.19e-266	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPANDNHF_00133	5.92e-80	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NPANDNHF_00134	1.57e-68	-	-	-	S	-	-	-	Membrane
NPANDNHF_00135	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NPANDNHF_00136	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NPANDNHF_00137	8.4e-66	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NPANDNHF_00138	1.68e-36	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
NPANDNHF_00139	5.1e-150	-	-	-	T	-	-	-	diguanylate cyclase activity
NPANDNHF_00140	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
NPANDNHF_00141	2.45e-255	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
NPANDNHF_00142	4.24e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
NPANDNHF_00143	1.33e-237	-	-	-	-	-	-	-	-
NPANDNHF_00144	3.21e-162	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NPANDNHF_00145	2.46e-49	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
NPANDNHF_00146	2.13e-182	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
NPANDNHF_00147	6.22e-197	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NPANDNHF_00148	7e-134	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NPANDNHF_00149	1.61e-121	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPANDNHF_00150	3e-277	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
NPANDNHF_00151	1.34e-254	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NPANDNHF_00152	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NPANDNHF_00153	1.06e-243	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NPANDNHF_00154	2.83e-204	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NPANDNHF_00155	1.41e-49	-	-	-	M	-	-	-	LysM domain
NPANDNHF_00156	5.6e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
NPANDNHF_00157	1.29e-63	-	-	-	M	-	-	-	LysM domain protein
NPANDNHF_00158	3.91e-116	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NPANDNHF_00159	1.05e-108	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
NPANDNHF_00161	1.61e-90	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NPANDNHF_00162	1.84e-130	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPANDNHF_00163	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPANDNHF_00164	3.98e-92	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
NPANDNHF_00165	9.9e-105	ylmH	-	-	S	-	-	-	S4 domain protein
NPANDNHF_00166	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NPANDNHF_00167	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPANDNHF_00168	4.52e-229	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPANDNHF_00169	6.07e-240	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPANDNHF_00170	5.65e-77	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPANDNHF_00171	3.02e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPANDNHF_00172	4.21e-233	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPANDNHF_00173	2.98e-171	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPANDNHF_00174	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPANDNHF_00175	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
NPANDNHF_00176	1.05e-179	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPANDNHF_00177	3.76e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NPANDNHF_00179	5.43e-196	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NPANDNHF_00180	1.16e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NPANDNHF_00181	2.19e-123	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NPANDNHF_00182	9.26e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NPANDNHF_00183	1.41e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_00184	3.02e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NPANDNHF_00185	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
NPANDNHF_00186	4.14e-97	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NPANDNHF_00187	2.3e-71	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NPANDNHF_00188	1.64e-121	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NPANDNHF_00189	3.89e-206	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NPANDNHF_00190	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
NPANDNHF_00191	2.27e-102	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NPANDNHF_00192	1.71e-169	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NPANDNHF_00193	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPANDNHF_00194	1.44e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPANDNHF_00195	1.02e-204	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NPANDNHF_00196	6.54e-223	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPANDNHF_00197	6.33e-73	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NPANDNHF_00198	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPANDNHF_00199	1.03e-31	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NPANDNHF_00200	5.46e-246	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NPANDNHF_00202	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
NPANDNHF_00208	9.71e-28	-	-	-	-	-	-	-	-
NPANDNHF_00209	1.04e-34	-	-	-	V	-	-	-	HNH nucleases
NPANDNHF_00210	1.16e-14	-	-	-	S	-	-	-	Phage terminase, small subunit
NPANDNHF_00211	1.91e-225	-	-	-	S	-	-	-	Terminase
NPANDNHF_00212	3.88e-101	-	-	-	S	-	-	-	Phage portal protein
NPANDNHF_00213	1.17e-65	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Serine dehydrogenase proteinase
NPANDNHF_00214	1.64e-126	-	-	-	S	-	-	-	Phage capsid family
NPANDNHF_00215	1.78e-11	-	-	-	-	-	-	-	-
NPANDNHF_00216	1.75e-30	-	-	-	-	-	-	-	-
NPANDNHF_00217	2.08e-39	-	-	-	-	-	-	-	-
NPANDNHF_00221	3.74e-187	-	-	-	S	-	-	-	peptidoglycan catabolic process
NPANDNHF_00222	0.000263	-	-	-	-	-	-	-	-
NPANDNHF_00223	4.42e-60	-	-	-	M	-	-	-	Prophage endopeptidase tail
NPANDNHF_00224	1.02e-18	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
NPANDNHF_00225	6.8e-18	-	-	-	-	-	-	-	-
NPANDNHF_00227	2.26e-14	-	-	-	S	-	-	-	Bacteriophage holin family
NPANDNHF_00228	1.51e-121	-	-	-	M	-	-	-	hydrolase, family 25
NPANDNHF_00230	1.85e-236	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPANDNHF_00231	4.83e-53	-	-	-	S	-	-	-	ASCH
NPANDNHF_00232	3.9e-91	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
NPANDNHF_00233	1.69e-147	-	-	-	S	-	-	-	EDD domain protein, DegV family
NPANDNHF_00234	3.91e-48	-	-	-	K	-	-	-	Transcriptional regulator
NPANDNHF_00235	6.64e-254	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NPANDNHF_00236	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPANDNHF_00237	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPANDNHF_00238	9.71e-107	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPANDNHF_00239	6.49e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
NPANDNHF_00241	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NPANDNHF_00242	1.19e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPANDNHF_00243	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NPANDNHF_00244	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NPANDNHF_00245	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPANDNHF_00246	5.64e-256	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPANDNHF_00247	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NPANDNHF_00248	3.32e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NPANDNHF_00249	3.1e-120	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPANDNHF_00251	1.47e-105	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NPANDNHF_00252	4.02e-164	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPANDNHF_00253	6.67e-221	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NPANDNHF_00254	1.45e-172	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NPANDNHF_00255	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPANDNHF_00256	1.56e-256	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NPANDNHF_00257	3.18e-189	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NPANDNHF_00258	2.44e-174	-	-	-	EG	-	-	-	EamA-like transporter family
NPANDNHF_00259	2.91e-83	-	-	-	L	-	-	-	DNA alkylation repair enzyme
NPANDNHF_00260	4.12e-231	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NPANDNHF_00261	3.3e-131	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPANDNHF_00262	3.94e-97	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NPANDNHF_00263	5.86e-185	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
NPANDNHF_00266	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NPANDNHF_00267	9.11e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NPANDNHF_00268	3.99e-154	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NPANDNHF_00269	1.92e-103	yqeM	-	-	Q	-	-	-	Methyltransferase
NPANDNHF_00270	2.79e-65	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPANDNHF_00271	1.88e-88	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NPANDNHF_00272	4.98e-99	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPANDNHF_00273	3.89e-40	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NPANDNHF_00274	1.46e-229	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NPANDNHF_00275	1.92e-90	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NPANDNHF_00276	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPANDNHF_00277	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NPANDNHF_00278	5.1e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPANDNHF_00279	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPANDNHF_00280	3.46e-138	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NPANDNHF_00281	1.38e-94	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
NPANDNHF_00282	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPANDNHF_00283	4.32e-62	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPANDNHF_00284	1.27e-138	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPANDNHF_00285	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPANDNHF_00286	1.42e-88	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NPANDNHF_00287	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
NPANDNHF_00288	2.49e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NPANDNHF_00289	1.35e-295	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NPANDNHF_00290	1.23e-97	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPANDNHF_00291	1.41e-57	ytpP	-	-	CO	-	-	-	Thioredoxin
NPANDNHF_00292	4.74e-130	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPANDNHF_00293	9.69e-125	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
NPANDNHF_00294	7.95e-88	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NPANDNHF_00295	8.15e-122	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_00296	1.1e-68	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NPANDNHF_00298	8.07e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPANDNHF_00299	7.62e-162	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPANDNHF_00300	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NPANDNHF_00301	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NPANDNHF_00303	9.23e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NPANDNHF_00304	2.86e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPANDNHF_00305	3.44e-92	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPANDNHF_00306	1.6e-59	ykuL	-	-	S	-	-	-	CBS domain
NPANDNHF_00307	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
NPANDNHF_00308	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPANDNHF_00309	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NPANDNHF_00310	1.89e-291	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPANDNHF_00311	5.17e-140	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NPANDNHF_00312	6.06e-130	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
NPANDNHF_00313	3.3e-160	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPANDNHF_00314	1.02e-274	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NPANDNHF_00315	4.61e-84	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPANDNHF_00316	2.71e-59	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPANDNHF_00317	4.97e-248	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPANDNHF_00318	1.27e-124	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NPANDNHF_00319	3.99e-129	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NPANDNHF_00320	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPANDNHF_00321	8.58e-129	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPANDNHF_00322	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NPANDNHF_00323	2.66e-86	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPANDNHF_00324	1.2e-48	-	-	-	-	-	-	-	-
NPANDNHF_00326	3.18e-224	-	-	-	S	-	-	-	Protein of unknown function DUF262
NPANDNHF_00327	2.17e-242	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NPANDNHF_00328	1.27e-103	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPANDNHF_00329	9.66e-80	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NPANDNHF_00330	1.14e-242	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NPANDNHF_00331	6.58e-245	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPANDNHF_00332	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NPANDNHF_00333	1.05e-225	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPANDNHF_00334	8.93e-73	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NPANDNHF_00338	7.31e-27	-	-	-	-	-	-	-	-
NPANDNHF_00342	4.44e-24	-	-	-	L	-	-	-	HNH endonuclease
NPANDNHF_00343	3.83e-42	-	-	-	L	-	-	-	Phage terminase, small subunit
NPANDNHF_00344	9.28e-269	-	-	-	S	-	-	-	Terminase
NPANDNHF_00345	4.12e-127	-	-	-	S	-	-	-	Phage portal protein, HK97 family
NPANDNHF_00346	1.5e-89	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
NPANDNHF_00347	1.98e-117	-	-	-	S	-	-	-	Phage capsid family
NPANDNHF_00354	4.79e-111	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
NPANDNHF_00355	3.42e-119	-	-	-	S	-	-	-	Phage tail protein
NPANDNHF_00356	0.0	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
NPANDNHF_00360	1.73e-18	-	-	-	-	-	-	-	-
NPANDNHF_00361	3.79e-10	-	-	-	S	-	-	-	by MetaGeneAnnotator
NPANDNHF_00365	1.01e-13	-	-	-	S	-	-	-	Bacteriophage holin
NPANDNHF_00366	1.95e-164	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NPANDNHF_00370	2.84e-110	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPANDNHF_00371	7.94e-88	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPANDNHF_00372	1.39e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NPANDNHF_00373	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPANDNHF_00374	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPANDNHF_00375	5.7e-164	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPANDNHF_00376	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NPANDNHF_00377	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPANDNHF_00378	5.6e-17	-	-	-	-	-	-	-	-
NPANDNHF_00379	1.24e-183	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NPANDNHF_00380	6.01e-55	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
NPANDNHF_00381	1.25e-148	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NPANDNHF_00382	2.15e-97	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NPANDNHF_00383	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPANDNHF_00384	7.24e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPANDNHF_00385	3.62e-72	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
NPANDNHF_00386	4.45e-55	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPANDNHF_00387	1.69e-164	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPANDNHF_00388	7.14e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPANDNHF_00389	1.07e-256	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NPANDNHF_00390	1.49e-140	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPANDNHF_00391	1.12e-234	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPANDNHF_00392	6.09e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPANDNHF_00393	1.43e-112	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPANDNHF_00394	1.83e-172	-	-	-	K	-	-	-	Transcriptional regulator
NPANDNHF_00395	1.54e-184	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NPANDNHF_00396	5.73e-148	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
NPANDNHF_00397	1.65e-217	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPANDNHF_00398	3.49e-111	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NPANDNHF_00400	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPANDNHF_00401	6.61e-219	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NPANDNHF_00402	2.19e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
NPANDNHF_00403	4.15e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
NPANDNHF_00404	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NPANDNHF_00405	2.15e-51	-	-	-	-	-	-	-	-
NPANDNHF_00407	3.97e-70	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPANDNHF_00408	1.28e-130	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
NPANDNHF_00409	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPANDNHF_00410	6.13e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPANDNHF_00411	3.27e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPANDNHF_00412	3.54e-87	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NPANDNHF_00413	2.72e-136	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_00414	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NPANDNHF_00415	6.47e-168	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NPANDNHF_00416	1.69e-201	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPANDNHF_00417	1.26e-132	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NPANDNHF_00418	3.85e-153	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPANDNHF_00419	8.99e-212	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPANDNHF_00420	6.6e-130	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPANDNHF_00421	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
NPANDNHF_00422	4.13e-296	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPANDNHF_00424	4.2e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
NPANDNHF_00425	3.71e-09	-	-	-	S	-	-	-	Putative adhesin
NPANDNHF_00426	2.01e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
NPANDNHF_00427	1.03e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
NPANDNHF_00428	3.61e-43	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
NPANDNHF_00429	9.54e-97	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
NPANDNHF_00430	4.49e-209	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPANDNHF_00431	1.93e-162	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NPANDNHF_00432	2.25e-85	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NPANDNHF_00433	1.13e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
NPANDNHF_00434	8.07e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NPANDNHF_00435	1.69e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
NPANDNHF_00436	2.25e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPANDNHF_00437	3.8e-102	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
NPANDNHF_00438	1.52e-120	baeS	-	-	T	-	-	-	Histidine kinase
NPANDNHF_00439	1.07e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
NPANDNHF_00440	5.94e-148	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NPANDNHF_00441	3.68e-51	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPANDNHF_00442	1.88e-42	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NPANDNHF_00443	1.41e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NPANDNHF_00444	3.08e-50	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NPANDNHF_00445	8.39e-75	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NPANDNHF_00446	5.62e-92	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
NPANDNHF_00447	1.58e-115	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPANDNHF_00448	4.43e-70	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NPANDNHF_00449	1.76e-110	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
NPANDNHF_00450	9.44e-27	-	-	-	-	-	-	-	-
NPANDNHF_00451	7.65e-19	-	-	-	M	-	-	-	Glycosyl transferase family 2
NPANDNHF_00452	5.79e-67	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NPANDNHF_00453	1.53e-74	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
NPANDNHF_00454	8.44e-145	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
NPANDNHF_00455	7.87e-229	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NPANDNHF_00456	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPANDNHF_00457	1.35e-271	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NPANDNHF_00458	1.88e-185	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NPANDNHF_00459	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPANDNHF_00460	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
NPANDNHF_00461	5.88e-164	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPANDNHF_00462	3.03e-162	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NPANDNHF_00463	6.31e-204	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NPANDNHF_00464	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPANDNHF_00465	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NPANDNHF_00466	1.5e-22	-	-	-	-	-	-	-	-
NPANDNHF_00467	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NPANDNHF_00468	3.55e-31	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
NPANDNHF_00469	3.3e-131	-	-	-	G	-	-	-	MucBP domain
NPANDNHF_00470	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NPANDNHF_00471	6.98e-252	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NPANDNHF_00472	1.26e-207	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NPANDNHF_00473	8.74e-225	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPANDNHF_00474	1.84e-138	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NPANDNHF_00475	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NPANDNHF_00476	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
NPANDNHF_00477	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NPANDNHF_00478	4.91e-147	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NPANDNHF_00479	3.8e-201	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NPANDNHF_00480	1e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
NPANDNHF_00481	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NPANDNHF_00482	3.14e-242	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPANDNHF_00483	3.85e-80	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NPANDNHF_00485	3.16e-30	-	-	-	S	-	-	-	Cytochrome B5
NPANDNHF_00486	7.55e-53	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NPANDNHF_00487	2.36e-74	-	-	-	-	-	-	-	-
NPANDNHF_00488	1e-121	-	-	-	L	-	-	-	Probable transposase
NPANDNHF_00489	1.77e-80	-	-	-	L	-	-	-	Resolvase, N-terminal domain
NPANDNHF_00490	1.8e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPANDNHF_00491	2.69e-195	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
NPANDNHF_00492	1.8e-114	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
NPANDNHF_00493	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NPANDNHF_00495	2.04e-179	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPANDNHF_00496	1.5e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPANDNHF_00497	1.87e-282	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPANDNHF_00498	1.15e-224	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPANDNHF_00499	3.82e-82	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
NPANDNHF_00500	1.01e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NPANDNHF_00502	4.31e-94	-	-	-	S	-	-	-	Cell surface protein
NPANDNHF_00507	0.000128	vpr	3.4.21.96	-	DO	ko:K01361,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	PA domain
NPANDNHF_00509	2.53e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
NPANDNHF_00510	3.37e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
NPANDNHF_00511	5.21e-209	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NPANDNHF_00512	2.12e-68	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPANDNHF_00513	4.23e-14	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
NPANDNHF_00514	2.23e-228	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
NPANDNHF_00515	6.53e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NPANDNHF_00516	6.4e-192	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NPANDNHF_00518	7.07e-53	-	-	-	K	-	-	-	LytTr DNA-binding domain
NPANDNHF_00519	4.37e-143	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
NPANDNHF_00520	3.9e-264	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NPANDNHF_00521	7.37e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NPANDNHF_00522	1.2e-197	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPANDNHF_00523	8.6e-230	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NPANDNHF_00524	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPANDNHF_00525	3.98e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPANDNHF_00526	3.07e-254	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NPANDNHF_00527	7.53e-277	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NPANDNHF_00528	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPANDNHF_00529	2.18e-72	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPANDNHF_00530	3.17e-78	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
NPANDNHF_00531	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NPANDNHF_00532	1.02e-26	-	-	-	S	-	-	-	Cupredoxin-like domain
NPANDNHF_00533	5.2e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
NPANDNHF_00534	4.12e-189	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NPANDNHF_00535	4.82e-168	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NPANDNHF_00536	4.75e-102	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NPANDNHF_00537	5.9e-178	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NPANDNHF_00538	6.91e-254	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NPANDNHF_00539	1.78e-149	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NPANDNHF_00540	5.91e-47	-	-	-	C	-	-	-	FMN_bind
NPANDNHF_00541	2.56e-203	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NPANDNHF_00542	1.2e-248	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NPANDNHF_00543	9.93e-94	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NPANDNHF_00544	3.35e-165	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
NPANDNHF_00545	5.93e-128	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NPANDNHF_00546	1.8e-103	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NPANDNHF_00547	3.84e-12	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NPANDNHF_00548	3.46e-78	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
NPANDNHF_00549	1.22e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPANDNHF_00551	1.94e-289	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPANDNHF_00552	8.42e-83	-	-	-	C	-	-	-	FMN binding
NPANDNHF_00553	1.24e-260	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NPANDNHF_00554	3.69e-85	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NPANDNHF_00555	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NPANDNHF_00558	2.97e-130	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NPANDNHF_00559	9.53e-79	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
NPANDNHF_00560	4.4e-203	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPANDNHF_00561	9.14e-37	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NPANDNHF_00562	3.63e-267	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NPANDNHF_00563	1.38e-249	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPANDNHF_00564	4.35e-301	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPANDNHF_00565	2.77e-19	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
NPANDNHF_00566	7.01e-75	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPANDNHF_00567	7.04e-121	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPANDNHF_00568	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NPANDNHF_00569	3.59e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NPANDNHF_00570	1.66e-163	-	-	-	C	-	-	-	Oxidoreductase
NPANDNHF_00571	3.97e-224	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NPANDNHF_00572	1.84e-90	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
NPANDNHF_00573	1.25e-207	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
NPANDNHF_00574	7.64e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
NPANDNHF_00575	1.22e-74	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
NPANDNHF_00576	5.05e-131	-	-	-	S	-	-	-	Domain of unknown function (DUF4343)
NPANDNHF_00577	0.0	-	-	-	L	-	-	-	helicase activity
NPANDNHF_00578	4.03e-231	-	-	-	K	-	-	-	DNA binding
NPANDNHF_00579	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
NPANDNHF_00580	2.98e-280	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
NPANDNHF_00583	1.37e-151	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
NPANDNHF_00584	5.49e-268	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPANDNHF_00585	5.09e-183	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NPANDNHF_00586	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPANDNHF_00587	7.24e-295	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPANDNHF_00588	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPANDNHF_00589	6.9e-205	camS	-	-	S	-	-	-	sex pheromone
NPANDNHF_00590	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPANDNHF_00591	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NPANDNHF_00592	1.49e-185	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NPANDNHF_00595	1.13e-233	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPANDNHF_00596	3e-174	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NPANDNHF_00597	4.02e-60	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NPANDNHF_00598	2.76e-257	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPANDNHF_00599	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPANDNHF_00600	1.39e-23	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NPANDNHF_00601	5.54e-139	dkgB	-	-	S	-	-	-	reductase
NPANDNHF_00602	1.82e-33	-	-	-	-	-	-	-	-
NPANDNHF_00603	2.85e-94	-	-	-	F	-	-	-	Phosphorylase superfamily
NPANDNHF_00604	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NPANDNHF_00605	6.96e-13	bCE_4747	-	-	S	-	-	-	Belongs to the UPF0173 family
NPANDNHF_00606	2.32e-228	-	-	-	L	-	-	-	Probable transposase
NPANDNHF_00607	1.3e-52	ytkL	-	-	S	-	-	-	Beta-lactamase superfamily domain
NPANDNHF_00608	2.02e-123	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPANDNHF_00609	4.8e-158	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NPANDNHF_00610	9.53e-110	-	-	-	S	-	-	-	overlaps another CDS with the same product name
NPANDNHF_00612	2.32e-61	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
NPANDNHF_00614	7.85e-27	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
NPANDNHF_00616	2.07e-78	-	-	-	-	-	-	-	-
NPANDNHF_00617	1.3e-133	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
NPANDNHF_00618	3.05e-112	-	-	-	S	-	-	-	hydrolase
NPANDNHF_00619	1.99e-260	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NPANDNHF_00620	1.42e-109	-	-	-	F	-	-	-	glutamine amidotransferase
NPANDNHF_00621	1.27e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NPANDNHF_00622	7.06e-57	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPANDNHF_00623	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPANDNHF_00625	4.42e-253	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPANDNHF_00626	9.6e-241	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NPANDNHF_00627	2.05e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NPANDNHF_00628	1.59e-79	-	-	-	-	-	-	-	-
NPANDNHF_00629	3.35e-310	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
NPANDNHF_00631	8.73e-152	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPANDNHF_00632	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPANDNHF_00633	1.55e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPANDNHF_00634	1.77e-192	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPANDNHF_00635	7.82e-116	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NPANDNHF_00636	4.9e-239	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NPANDNHF_00637	3.24e-144	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPANDNHF_00638	9.24e-75	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NPANDNHF_00639	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NPANDNHF_00640	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NPANDNHF_00641	2.44e-302	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NPANDNHF_00642	2.21e-305	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPANDNHF_00643	1.03e-178	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPANDNHF_00644	2.39e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPANDNHF_00645	7.23e-130	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPANDNHF_00646	9.29e-286	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NPANDNHF_00647	1.12e-187	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPANDNHF_00648	4.33e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPANDNHF_00649	3.67e-262	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPANDNHF_00650	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NPANDNHF_00651	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NPANDNHF_00652	1.86e-73	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPANDNHF_00653	2.74e-145	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NPANDNHF_00654	3.1e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NPANDNHF_00655	1.24e-250	-	-	-	E	ko:K03294	-	ko00000	amino acid
NPANDNHF_00656	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPANDNHF_00657	1.57e-254	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPANDNHF_00658	4.77e-40	-	-	-	-	-	-	-	-
NPANDNHF_00662	3.01e-54	polC_2	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPANDNHF_00665	2.16e-30	-	-	-	K	-	-	-	Helix-turn-helix domain
NPANDNHF_00667	2.5e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPANDNHF_00668	2.03e-179	-	-	-	K	-	-	-	Transcriptional regulator
NPANDNHF_00674	2.19e-100	-	-	-	S	-	-	-	Siphovirus Gp157
NPANDNHF_00675	8.24e-297	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NPANDNHF_00677	2.43e-149	-	-	-	L	-	-	-	AAA domain
NPANDNHF_00678	4.04e-109	-	-	-	-	-	-	-	-
NPANDNHF_00679	5.21e-180	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
NPANDNHF_00680	3.82e-294	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
NPANDNHF_00681	1.27e-66	-	-	-	S	-	-	-	VRR_NUC
NPANDNHF_00684	5.49e-33	-	-	-	M	-	-	-	Rib/alpha-like repeat
NPANDNHF_00685	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NPANDNHF_00686	2.3e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
NPANDNHF_00687	4.74e-52	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPANDNHF_00688	3.13e-75	napB	-	-	K	-	-	-	transcriptional
NPANDNHF_00689	7.97e-90	mleR	-	-	K	-	-	-	LysR family
NPANDNHF_00690	1.69e-313	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
NPANDNHF_00691	1.36e-28	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
NPANDNHF_00692	5.7e-82	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NPANDNHF_00693	7.37e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NPANDNHF_00694	3.22e-95	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPANDNHF_00695	6.35e-254	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NPANDNHF_00696	1.84e-47	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NPANDNHF_00697	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NPANDNHF_00698	6.48e-123	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NPANDNHF_00699	4.19e-147	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPANDNHF_00700	4.86e-118	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPANDNHF_00701	1.27e-228	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
NPANDNHF_00703	1.96e-54	-	-	-	-	-	-	-	-
NPANDNHF_00704	1.32e-41	-	-	-	K	-	-	-	GNAT family
NPANDNHF_00705	3.95e-263	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NPANDNHF_00706	1.46e-277	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NPANDNHF_00707	1.14e-35	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NPANDNHF_00708	3.1e-274	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NPANDNHF_00709	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NPANDNHF_00710	1e-208	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NPANDNHF_00711	9.63e-158	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NPANDNHF_00712	3e-242	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
NPANDNHF_00713	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NPANDNHF_00714	6.98e-215	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NPANDNHF_00715	1.13e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NPANDNHF_00716	7.62e-161	mocA	-	-	S	-	-	-	Oxidoreductase
NPANDNHF_00717	4.62e-200	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NPANDNHF_00720	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
NPANDNHF_00721	1.99e-178	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
NPANDNHF_00722	8.6e-87	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NPANDNHF_00723	5.54e-29	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NPANDNHF_00724	1.02e-205	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPANDNHF_00725	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NPANDNHF_00726	1.52e-126	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPANDNHF_00727	1.28e-39	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPANDNHF_00728	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPANDNHF_00729	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPANDNHF_00730	5.17e-48	-	-	-	P	ko:K12952	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
NPANDNHF_00731	4.04e-29	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
NPANDNHF_00732	3.91e-216	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
NPANDNHF_00733	0.0	ydaO	-	-	E	-	-	-	amino acid
NPANDNHF_00734	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
NPANDNHF_00735	8.67e-159	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NPANDNHF_00736	6.47e-68	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NPANDNHF_00737	7.08e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPANDNHF_00738	7.85e-119	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
NPANDNHF_00739	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPANDNHF_00740	3.57e-204	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPANDNHF_00741	8.78e-79	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NPANDNHF_00742	1.03e-110	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NPANDNHF_00743	1.04e-103	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPANDNHF_00744	1.02e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
NPANDNHF_00745	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NPANDNHF_00746	8.3e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPANDNHF_00747	2.04e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPANDNHF_00748	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NPANDNHF_00749	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPANDNHF_00750	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPANDNHF_00751	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPANDNHF_00752	2.28e-101	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
NPANDNHF_00753	4.12e-160	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NPANDNHF_00754	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NPANDNHF_00755	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NPANDNHF_00756	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPANDNHF_00758	5.29e-173	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
NPANDNHF_00759	2.01e-223	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPANDNHF_00760	1.99e-264	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NPANDNHF_00761	4.05e-164	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPANDNHF_00762	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPANDNHF_00763	2.02e-167	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPANDNHF_00764	7.94e-134	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NPANDNHF_00765	8.04e-212	yclK	-	-	T	-	-	-	Histidine kinase
NPANDNHF_00766	6.59e-190	-	-	-	E	-	-	-	Major Facilitator Superfamily
NPANDNHF_00767	4.45e-224	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NPANDNHF_00768	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NPANDNHF_00769	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPANDNHF_00770	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPANDNHF_00771	1.94e-53	-	-	-	-	-	-	-	-
NPANDNHF_00772	1.18e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPANDNHF_00773	4.36e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPANDNHF_00774	7.01e-181	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NPANDNHF_00775	7.04e-73	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NPANDNHF_00776	3.34e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPANDNHF_00777	3e-146	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NPANDNHF_00778	3.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
NPANDNHF_00779	4.8e-163	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPANDNHF_00780	4.54e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
NPANDNHF_00781	5.91e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPANDNHF_00782	1.59e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NPANDNHF_00783	5.34e-164	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NPANDNHF_00784	6.04e-24	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NPANDNHF_00785	8.54e-251	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPANDNHF_00786	1.61e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPANDNHF_00787	2.04e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NPANDNHF_00788	2.48e-125	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NPANDNHF_00789	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPANDNHF_00790	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NPANDNHF_00791	5.2e-137	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NPANDNHF_00792	7.38e-186	ymfH	-	-	S	-	-	-	Peptidase M16
NPANDNHF_00793	1.82e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NPANDNHF_00794	8.29e-84	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
NPANDNHF_00795	3.46e-110	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPANDNHF_00796	5.27e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPANDNHF_00797	4.38e-256	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NPANDNHF_00798	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPANDNHF_00799	6.99e-288	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPANDNHF_00800	2.19e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPANDNHF_00801	7.18e-194	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPANDNHF_00802	1.66e-230	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NPANDNHF_00803	2.08e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NPANDNHF_00804	3.02e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
NPANDNHF_00806	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
NPANDNHF_00808	1.68e-263	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
NPANDNHF_00809	3.54e-150	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
NPANDNHF_00810	4.95e-311	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
NPANDNHF_00811	3.13e-85	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
NPANDNHF_00812	1.94e-184	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPANDNHF_00813	3.5e-18	-	-	-	-	-	-	-	-
NPANDNHF_00814	1.08e-154	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NPANDNHF_00815	1.06e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPANDNHF_00816	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPANDNHF_00817	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NPANDNHF_00818	4.49e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPANDNHF_00819	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NPANDNHF_00820	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NPANDNHF_00821	1.75e-21	cvpA	-	-	S	-	-	-	Colicin V production protein
NPANDNHF_00822	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPANDNHF_00823	2.59e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NPANDNHF_00824	5.05e-103	-	-	-	I	-	-	-	Pfam Lipase (class 3)
NPANDNHF_00825	1.36e-10	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NPANDNHF_00826	1.39e-14	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NPANDNHF_00827	7.15e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NPANDNHF_00828	1.26e-93	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPANDNHF_00829	2.09e-52	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NPANDNHF_00832	2.84e-177	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPANDNHF_00833	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPANDNHF_00834	5.76e-273	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPANDNHF_00835	5.11e-255	oatA	-	-	I	-	-	-	Acyltransferase
NPANDNHF_00836	1.68e-22	-	-	-	-	-	-	-	-
NPANDNHF_00838	1.24e-178	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPANDNHF_00839	1.02e-129	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
NPANDNHF_00840	1.53e-264	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NPANDNHF_00841	3.03e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPANDNHF_00842	0.0	-	-	-	S	-	-	-	membrane
NPANDNHF_00843	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NPANDNHF_00844	2.11e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NPANDNHF_00845	5.09e-67	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
NPANDNHF_00847	1.97e-156	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NPANDNHF_00848	2.99e-252	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NPANDNHF_00849	2.94e-70	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NPANDNHF_00851	9.61e-60	arbY	-	-	M	-	-	-	family 8
NPANDNHF_00852	7.71e-191	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NPANDNHF_00853	9.44e-43	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NPANDNHF_00854	2.43e-42	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPANDNHF_00855	1.57e-37	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPANDNHF_00856	3.86e-05	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPANDNHF_00857	8.32e-44	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPANDNHF_00858	1.7e-136	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NPANDNHF_00859	2.67e-80	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NPANDNHF_00860	5.04e-21	-	-	-	M	-	-	-	PFAM glycosyl transferase family 8
NPANDNHF_00861	1.96e-67	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NPANDNHF_00862	5.87e-40	-	-	-	M	-	-	-	family 8
NPANDNHF_00863	1.99e-40	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPANDNHF_00864	8.91e-46	-	-	-	S	-	-	-	glycosyl transferase family 2
NPANDNHF_00865	7.22e-45	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NPANDNHF_00866	4.31e-35	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPANDNHF_00867	1.16e-54	arbY	-	-	M	-	-	-	family 8
NPANDNHF_00868	2.41e-50	arbY	-	-	M	-	-	-	family 8
NPANDNHF_00869	8.77e-184	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
NPANDNHF_00870	4.11e-185	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NPANDNHF_00871	5.93e-106	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPANDNHF_00872	4.31e-141	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NPANDNHF_00873	1.87e-252	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NPANDNHF_00874	3.77e-35	-	-	-	-	-	-	-	-
NPANDNHF_00875	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
NPANDNHF_00876	4.09e-77	-	-	-	T	-	-	-	Universal stress protein family
NPANDNHF_00878	5.42e-272	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPANDNHF_00879	3.5e-214	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NPANDNHF_00880	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NPANDNHF_00881	2.4e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPANDNHF_00882	1.87e-166	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPANDNHF_00883	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPANDNHF_00884	2.49e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NPANDNHF_00885	4.16e-117	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPANDNHF_00886	8.69e-63	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NPANDNHF_00887	3.7e-29	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NPANDNHF_00888	7.72e-43	yabO	-	-	J	-	-	-	S4 domain protein
NPANDNHF_00889	4.66e-173	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NPANDNHF_00890	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPANDNHF_00891	1.45e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPANDNHF_00892	1.65e-201	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NPANDNHF_00893	2.2e-110	-	-	-	S	-	-	-	(CBS) domain
NPANDNHF_00894	4.44e-180	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPANDNHF_00895	4.76e-260	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPANDNHF_00896	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NPANDNHF_00897	2.34e-72	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
NPANDNHF_00898	9.32e-131	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NPANDNHF_00899	7.63e-145	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NPANDNHF_00900	1.08e-68	-	-	-	M	-	-	-	LysM domain protein
NPANDNHF_00901	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NPANDNHF_00902	9.1e-111	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NPANDNHF_00903	1.48e-41	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
NPANDNHF_00904	1.52e-138	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NPANDNHF_00905	1.48e-109	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_00906	2.68e-77	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NPANDNHF_00907	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NPANDNHF_00908	6.21e-274	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
NPANDNHF_00909	1.22e-63	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPANDNHF_00910	6.58e-86	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NPANDNHF_00911	7.13e-288	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NPANDNHF_00912	1.01e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
NPANDNHF_00913	4.34e-125	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NPANDNHF_00914	7.37e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NPANDNHF_00915	2.35e-155	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NPANDNHF_00916	7.48e-147	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPANDNHF_00917	6.43e-149	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPANDNHF_00918	2.26e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NPANDNHF_00919	1.21e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NPANDNHF_00920	1.39e-100	-	-	-	S	-	-	-	VIT family
NPANDNHF_00921	2.71e-107	-	-	-	S	-	-	-	membrane
NPANDNHF_00922	1.13e-52	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NPANDNHF_00923	5.92e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NPANDNHF_00924	3.39e-47	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NPANDNHF_00925	1.71e-96	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPANDNHF_00927	2.23e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPANDNHF_00929	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NPANDNHF_00930	5.13e-202	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NPANDNHF_00931	4.81e-54	-	-	-	S	-	-	-	VanZ like family
NPANDNHF_00932	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NPANDNHF_00933	6.66e-129	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPANDNHF_00934	3.19e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NPANDNHF_00935	1.95e-122	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NPANDNHF_00936	3.06e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
NPANDNHF_00937	7.13e-18	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
NPANDNHF_00941	7e-124	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NPANDNHF_00942	3.13e-239	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NPANDNHF_00943	5.12e-20	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPANDNHF_00944	6.92e-46	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NPANDNHF_00945	4.29e-77	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NPANDNHF_00946	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPANDNHF_00947	1.28e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NPANDNHF_00948	3.79e-118	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NPANDNHF_00949	2.32e-118	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NPANDNHF_00950	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
NPANDNHF_00952	4.83e-61	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NPANDNHF_00954	3.64e-22	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPANDNHF_00955	2.82e-85	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NPANDNHF_00958	6.16e-68	-	-	-	S	-	-	-	EVIDENCE BY HOMOLOGY BIO14.03 Phage related functions and prophages
NPANDNHF_00959	2.22e-84	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
NPANDNHF_00961	1.78e-158	yvgN	-	-	C	-	-	-	Aldo keto reductase
NPANDNHF_00964	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NPANDNHF_00965	7.76e-48	-	-	-	-	-	-	-	-
NPANDNHF_00967	3.22e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
NPANDNHF_00968	1.32e-20	bglG	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
NPANDNHF_00969	3.22e-78	-	-	-	L	-	-	-	Resolvase, N-terminal domain
NPANDNHF_00970	2.91e-120	-	-	-	L	-	-	-	Probable transposase
NPANDNHF_00971	1.88e-45	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
NPANDNHF_00972	3.24e-142	-	-	-	L	-	-	-	Initiator Replication protein
NPANDNHF_00975	7.19e-219	-	-	-	L	-	-	-	PLD-like domain
NPANDNHF_00976	0.000352	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
NPANDNHF_00978	2.55e-290	fusA1	-	-	J	-	-	-	elongation factor G
NPANDNHF_00979	3.83e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPANDNHF_00980	5.75e-09	-	-	-	-	-	-	-	-
NPANDNHF_00981	9.08e-63	potE	-	-	E	-	-	-	Amino Acid
NPANDNHF_00982	5.38e-38	yphH	-	-	S	-	-	-	Cupin domain
NPANDNHF_00983	2.84e-107	-	-	-	C	-	-	-	nitroreductase
NPANDNHF_00984	3.08e-106	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
NPANDNHF_00985	1.16e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
NPANDNHF_00986	8.62e-214	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NPANDNHF_00987	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
NPANDNHF_00988	1.53e-57	-	-	-	V	-	-	-	type I restriction modification DNA specificity domain
NPANDNHF_00989	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NPANDNHF_00990	2.7e-106	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NPANDNHF_00991	1.23e-310	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NPANDNHF_00992	6.99e-173	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPANDNHF_00993	2.75e-81	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
NPANDNHF_00994	1.88e-27	-	-	-	S	ko:K19092	-	ko00000,ko02048	addiction module toxin, RelE StbE family
NPANDNHF_00995	3.84e-34	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
NPANDNHF_00996	7.57e-75	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	PFAM Type I restriction modification DNA specificity domain
NPANDNHF_00997	1.14e-49	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
NPANDNHF_00999	1.53e-192	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPANDNHF_01000	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPANDNHF_01001	3.63e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NPANDNHF_01002	3.4e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
NPANDNHF_01005	2.42e-28	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
NPANDNHF_01006	6.74e-87	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
NPANDNHF_01007	7.6e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPANDNHF_01008	7.05e-123	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NPANDNHF_01009	4.6e-90	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
NPANDNHF_01010	1.49e-176	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NPANDNHF_01011	1.73e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NPANDNHF_01012	2.41e-270	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NPANDNHF_01013	1.71e-174	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPANDNHF_01014	1.13e-89	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPANDNHF_01015	4.43e-181	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
NPANDNHF_01017	1.12e-44	-	-	-	-	-	-	-	-
NPANDNHF_01019	1.03e-55	-	-	-	S	-	-	-	YjcQ protein
NPANDNHF_01022	1.39e-128	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
NPANDNHF_01023	1.85e-89	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPANDNHF_01024	3.7e-101	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NPANDNHF_01025	8.62e-73	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPANDNHF_01026	7.02e-67	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NPANDNHF_01027	2.97e-101	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPANDNHF_01030	1.22e-08	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NPANDNHF_01031	6.96e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NPANDNHF_01032	1.66e-11	yhaI	-	-	S	-	-	-	membrane
NPANDNHF_01033	9.6e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NPANDNHF_01036	9.75e-07	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
NPANDNHF_01037	4.69e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPANDNHF_01038	5.81e-99	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NPANDNHF_01039	1.6e-33	-	-	-	-	-	-	-	-
NPANDNHF_01040	2.69e-09	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPANDNHF_01041	6.81e-103	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NPANDNHF_01042	1.7e-175	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NPANDNHF_01043	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NPANDNHF_01044	9.5e-35	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
NPANDNHF_01045	1.18e-69	-	-	-	F	-	-	-	glutamine amidotransferase
NPANDNHF_01046	5.86e-189	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NPANDNHF_01047	3.51e-146	degV	-	-	S	-	-	-	EDD domain protein, DegV family
NPANDNHF_01048	5.11e-293	cadA	-	-	P	-	-	-	P-type ATPase
NPANDNHF_01049	0.0	-	-	-	E	-	-	-	Amino acid permease
NPANDNHF_01050	4.47e-108	-	-	-	S	-	-	-	Membrane
NPANDNHF_01051	3.27e-57	cps3F	-	-	-	-	-	-	-
NPANDNHF_01052	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
NPANDNHF_01053	4.7e-192	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NPANDNHF_01054	1.2e-112	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
NPANDNHF_01055	5.37e-279	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NPANDNHF_01056	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NPANDNHF_01057	1.78e-17	-	-	-	-	-	-	-	-
NPANDNHF_01058	6.8e-50	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NPANDNHF_01059	8.57e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
NPANDNHF_01060	2.72e-186	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NPANDNHF_01061	4.36e-291	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NPANDNHF_01062	9.5e-231	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPANDNHF_01063	7.47e-213	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NPANDNHF_01064	1.49e-223	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NPANDNHF_01065	8.95e-14	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NPANDNHF_01066	2.89e-05	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
NPANDNHF_01067	4.33e-82	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NPANDNHF_01068	2.67e-174	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
NPANDNHF_01070	7.01e-225	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NPANDNHF_01071	1.17e-136	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NPANDNHF_01072	1.95e-279	pepF	-	-	E	-	-	-	Oligopeptidase F
NPANDNHF_01073	2.33e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
NPANDNHF_01074	1.26e-89	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NPANDNHF_01075	1.86e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
NPANDNHF_01076	4.44e-141	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NPANDNHF_01077	5.78e-12	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPANDNHF_01078	5.22e-192	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NPANDNHF_01079	9.05e-126	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NPANDNHF_01080	6.19e-283	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NPANDNHF_01081	3.57e-290	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPANDNHF_01082	3.94e-22	yneR	-	-	-	-	-	-	-
NPANDNHF_01083	2.8e-308	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NPANDNHF_01084	5.27e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPANDNHF_01085	1.32e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
NPANDNHF_01086	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NPANDNHF_01087	4.83e-83	-	-	-	D	-	-	-	peptidase
NPANDNHF_01088	2.84e-149	-	-	-	S	-	-	-	Glycosyl transferase family 2
NPANDNHF_01092	1.88e-34	-	-	-	M	-	-	-	CHAP domain
NPANDNHF_01094	7.87e-236	-	-	-	U	-	-	-	type IV secretory pathway VirB4
NPANDNHF_01097	3.66e-85	-	-	-	-	-	-	-	-
NPANDNHF_01098	6.38e-264	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
NPANDNHF_01102	6.14e-182	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
NPANDNHF_01105	2.68e-201	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
NPANDNHF_01106	9.53e-26	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
NPANDNHF_01107	2e-73	-	-	-	-	-	-	-	-
NPANDNHF_01109	1.75e-161	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
NPANDNHF_01110	7.24e-121	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
NPANDNHF_01111	1.4e-229	-	-	-	L	-	-	-	Probable transposase
NPANDNHF_01112	6.08e-67	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
NPANDNHF_01113	9.2e-16	-	-	-	S	-	-	-	YjcQ protein
NPANDNHF_01115	3.22e-140	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
NPANDNHF_01116	1.23e-34	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
NPANDNHF_01117	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NPANDNHF_01118	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPANDNHF_01119	4.33e-48	-	-	-	S	-	-	-	Enterocin A Immunity
NPANDNHF_01120	3.6e-104	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
NPANDNHF_01121	2.53e-72	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NPANDNHF_01122	7.79e-148	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NPANDNHF_01123	4.92e-20	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
NPANDNHF_01124	1.82e-213	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
NPANDNHF_01127	2.17e-16	-	-	-	-	-	-	-	-
NPANDNHF_01130	4.07e-34	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the agmatine deiminase family
NPANDNHF_01132	1.3e-52	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
NPANDNHF_01133	2.76e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NPANDNHF_01134	1.66e-85	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
NPANDNHF_01136	5.53e-140	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
NPANDNHF_01137	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NPANDNHF_01138	2.5e-59	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
NPANDNHF_01139	4.55e-68	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NPANDNHF_01140	8.95e-70	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NPANDNHF_01141	1.1e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPANDNHF_01142	3.65e-45	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
NPANDNHF_01143	1.4e-96	azlC	-	-	E	-	-	-	branched-chain amino acid
NPANDNHF_01144	1.13e-75	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
NPANDNHF_01145	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
NPANDNHF_01146	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NPANDNHF_01147	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
NPANDNHF_01148	3.78e-241	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
NPANDNHF_01149	1.85e-96	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NPANDNHF_01150	8.07e-142	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NPANDNHF_01152	2.04e-264	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NPANDNHF_01153	4.08e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPANDNHF_01154	6.92e-143	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
NPANDNHF_01155	2.16e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
NPANDNHF_01156	1.4e-88	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
NPANDNHF_01157	4.88e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
NPANDNHF_01158	8.82e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NPANDNHF_01159	1.08e-217	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NPANDNHF_01160	2.19e-257	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
NPANDNHF_01161	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPANDNHF_01162	5.03e-237	noxE	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NPANDNHF_01163	1.32e-57	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NPANDNHF_01165	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPANDNHF_01166	2.89e-128	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_01167	1.36e-121	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NPANDNHF_01168	3.75e-49	-	-	-	K	-	-	-	Transcriptional regulator
NPANDNHF_01169	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
NPANDNHF_01170	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NPANDNHF_01171	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPANDNHF_01172	5.73e-234	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
NPANDNHF_01173	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
NPANDNHF_01174	3.12e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_01176	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
NPANDNHF_01177	2e-199	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NPANDNHF_01178	4.49e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPANDNHF_01179	1.42e-197	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NPANDNHF_01180	3.93e-180	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPANDNHF_01181	3.52e-45	-	-	-	-	-	-	-	-
NPANDNHF_01182	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPANDNHF_01183	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NPANDNHF_01184	5.09e-83	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NPANDNHF_01186	1e-92	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NPANDNHF_01187	4.77e-79	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
NPANDNHF_01188	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NPANDNHF_01189	2.3e-90	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
NPANDNHF_01190	1.17e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NPANDNHF_01191	2.55e-130	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NPANDNHF_01192	8.74e-104	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NPANDNHF_01193	4.97e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NPANDNHF_01194	4.14e-138	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NPANDNHF_01195	3.11e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NPANDNHF_01196	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPANDNHF_01197	2.21e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NPANDNHF_01198	2.75e-46	-	-	-	-	-	-	-	-
NPANDNHF_01199	5.14e-132	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NPANDNHF_01200	1.6e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NPANDNHF_01201	6.01e-139	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NPANDNHF_01202	2.3e-70	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NPANDNHF_01203	2.85e-129	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NPANDNHF_01204	1.03e-111	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NPANDNHF_01205	1.31e-35	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
NPANDNHF_01206	2.7e-88	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NPANDNHF_01208	4.49e-192	-	-	-	EGP	-	-	-	Major Facilitator
NPANDNHF_01209	2.08e-81	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NPANDNHF_01210	1.85e-114	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NPANDNHF_01211	1.3e-47	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NPANDNHF_01212	2.33e-147	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NPANDNHF_01213	5.22e-77	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NPANDNHF_01214	4.45e-171	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
NPANDNHF_01215	4.21e-231	-	-	-	L	-	-	-	Probable transposase
NPANDNHF_01216	1.24e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
NPANDNHF_01217	6.27e-269	potE	-	-	E	-	-	-	Amino Acid
NPANDNHF_01218	2e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NPANDNHF_01219	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_01220	3.09e-53	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPANDNHF_01221	5.53e-171	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NPANDNHF_01222	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NPANDNHF_01224	3.15e-222	wchF	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
NPANDNHF_01225	5.25e-155	-	-	-	M	-	-	-	Glycosyltransferase Family 4
NPANDNHF_01226	1.27e-90	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
NPANDNHF_01227	2.76e-177	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NPANDNHF_01228	1.08e-126	lpg2	2.4.1.337	GT4	M	ko:K00754,ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	transferase activity, transferring glycosyl groups
NPANDNHF_01229	7.62e-95	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NPANDNHF_01230	5.66e-46	-	-	-	-	-	-	-	-
NPANDNHF_01231	1.54e-53	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NPANDNHF_01232	2.31e-21	-	-	-	L	-	-	-	Transposase
NPANDNHF_01234	1.4e-270	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
NPANDNHF_01235	7.17e-101	epsB	-	-	M	-	-	-	biosynthesis protein
NPANDNHF_01236	4.48e-117	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NPANDNHF_01237	1.72e-141	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NPANDNHF_01238	9.56e-164	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPANDNHF_01239	2.07e-116	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
NPANDNHF_01240	4.02e-183	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPANDNHF_01241	2.75e-131	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NPANDNHF_01242	7.33e-213	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPANDNHF_01243	2.94e-164	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NPANDNHF_01245	7.49e-81	-	-	-	D	-	-	-	Peptidase family M23
NPANDNHF_01246	3.88e-47	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPANDNHF_01247	8.45e-116	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
NPANDNHF_01248	6.87e-86	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
NPANDNHF_01249	3.84e-115	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NPANDNHF_01250	1.14e-67	cps3F	-	-	-	-	-	-	-
NPANDNHF_01251	2.29e-94	licD1	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
NPANDNHF_01252	1.32e-77	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPANDNHF_01253	2.65e-52	-	-	-	S	-	-	-	Peptidase_C39 like family
NPANDNHF_01254	1.39e-42	-	-	-	S	-	-	-	Acyltransferase family
NPANDNHF_01255	5.78e-249	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NPANDNHF_01256	2.97e-193	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NPANDNHF_01258	2.32e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NPANDNHF_01259	4.29e-270	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NPANDNHF_01260	6.74e-96	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NPANDNHF_01261	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NPANDNHF_01262	7.42e-109	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NPANDNHF_01263	2.35e-253	-	-	-	E	-	-	-	Amino acid permease
NPANDNHF_01264	1e-228	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
NPANDNHF_01265	2.86e-215	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPANDNHF_01266	1.39e-89	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
NPANDNHF_01267	1.31e-154	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
NPANDNHF_01268	9.8e-152	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
NPANDNHF_01269	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NPANDNHF_01270	5.64e-69	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
NPANDNHF_01271	2.04e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NPANDNHF_01272	8.68e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NPANDNHF_01273	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NPANDNHF_01274	2.24e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
NPANDNHF_01275	1.62e-119	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NPANDNHF_01276	2.02e-138	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
NPANDNHF_01277	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPANDNHF_01278	3.23e-82	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPANDNHF_01279	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NPANDNHF_01280	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPANDNHF_01281	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPANDNHF_01282	8.39e-194	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPANDNHF_01283	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
NPANDNHF_01284	1.27e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPANDNHF_01285	1.1e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPANDNHF_01286	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NPANDNHF_01287	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPANDNHF_01288	3.1e-137	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPANDNHF_01289	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
NPANDNHF_01290	1.17e-152	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NPANDNHF_01291	2.5e-67	-	-	-	K	-	-	-	LysR substrate binding domain
NPANDNHF_01293	4.83e-84	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
NPANDNHF_01294	1.18e-37	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NPANDNHF_01295	9.85e-28	ebh	-	-	D	-	-	-	interspecies interaction between organisms
NPANDNHF_01296	6.21e-149	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NPANDNHF_01297	1.39e-186	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NPANDNHF_01298	2.75e-94	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPANDNHF_01299	9.6e-261	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
NPANDNHF_01300	2.95e-176	-	-	-	S	-	-	-	interspecies interaction between organisms
NPANDNHF_01301	1.95e-63	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the accessory SecA2 SecY2 system specifically required for export of
NPANDNHF_01302	1.11e-100	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
NPANDNHF_01303	8.63e-127	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system protein Asp2
NPANDNHF_01304	1.4e-17	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec system protein Asp3
NPANDNHF_01305	3.34e-305	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPANDNHF_01308	3.35e-100	yycI	-	-	S	-	-	-	YycH protein
NPANDNHF_01309	1.33e-126	yycH	-	-	S	-	-	-	YycH protein
NPANDNHF_01310	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPANDNHF_01311	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NPANDNHF_01312	1.16e-134	yxeH	-	-	S	-	-	-	hydrolase
NPANDNHF_01313	1.63e-198	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	FMN-dependent dehydrogenase
NPANDNHF_01314	4.16e-212	-	-	-	EGP	-	-	-	Mycoplasma MFS transporter
NPANDNHF_01315	4.77e-288	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
NPANDNHF_01316	8.78e-269	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_01317	2.33e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NPANDNHF_01318	6.45e-218	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NPANDNHF_01319	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPANDNHF_01320	6.01e-70	-	-	-	-	-	-	-	-
NPANDNHF_01321	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPANDNHF_01322	3.15e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPANDNHF_01323	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPANDNHF_01324	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPANDNHF_01325	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NPANDNHF_01326	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPANDNHF_01327	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NPANDNHF_01328	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
NPANDNHF_01329	2.29e-139	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPANDNHF_01330	3.45e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPANDNHF_01331	5.29e-262	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NPANDNHF_01332	7.38e-313	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPANDNHF_01333	1.38e-195	yacL	-	-	S	-	-	-	domain protein
NPANDNHF_01334	8e-284	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPANDNHF_01335	1.38e-94	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
NPANDNHF_01336	1.17e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NPANDNHF_01338	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NPANDNHF_01341	1.5e-115	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPANDNHF_01342	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NPANDNHF_01343	8.17e-114	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPANDNHF_01344	1.26e-306	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPANDNHF_01345	7.58e-165	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPANDNHF_01346	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
NPANDNHF_01347	1.61e-54	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NPANDNHF_01349	2.66e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPANDNHF_01350	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
NPANDNHF_01351	4.1e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPANDNHF_01352	1.53e-40	-	-	-	S	-	-	-	Enterocin A Immunity
NPANDNHF_01353	7.36e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NPANDNHF_01354	5.68e-21	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NPANDNHF_01355	5.17e-285	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NPANDNHF_01356	9.74e-159	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPANDNHF_01357	1.98e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
NPANDNHF_01358	3.86e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NPANDNHF_01359	1.02e-105	lysR5	-	-	K	-	-	-	LysR substrate binding domain
NPANDNHF_01360	1.51e-71	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
NPANDNHF_01361	2.9e-14	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NPANDNHF_01362	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NPANDNHF_01363	5.56e-87	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NPANDNHF_01364	2.64e-308	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NPANDNHF_01365	2.28e-262	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPANDNHF_01366	7e-104	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NPANDNHF_01367	5.19e-133	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPANDNHF_01368	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NPANDNHF_01369	9.67e-105	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NPANDNHF_01370	1.25e-82	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPANDNHF_01371	2.93e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NPANDNHF_01372	1.9e-125	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPANDNHF_01373	3.64e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPANDNHF_01374	1.34e-268	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPANDNHF_01375	2.23e-80	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPANDNHF_01376	3.19e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
NPANDNHF_01377	1.36e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NPANDNHF_01378	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
NPANDNHF_01379	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPANDNHF_01380	1.1e-203	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPANDNHF_01381	5.33e-139	-	-	-	L	-	-	-	helicase
NPANDNHF_01382	1.22e-79	-	-	-	L	-	-	-	Resolvase, N terminal domain
NPANDNHF_01384	2.05e-19	-	-	-	-	-	-	-	-
NPANDNHF_01386	2.9e-181	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
NPANDNHF_01387	1.82e-43	-	-	-	-	-	-	-	-
NPANDNHF_01388	8.08e-06	-	-	-	L	-	-	-	Resolvase, N terminal domain
NPANDNHF_01389	1.28e-164	-	-	-	L	ko:K07498	-	ko00000	Transposase
NPANDNHF_01390	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Domain of unknown function DUF87
NPANDNHF_01391	1.39e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
NPANDNHF_01392	6.51e-69	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
NPANDNHF_01393	3.19e-59	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
NPANDNHF_01397	1.37e-65	-	-	-	L	-	-	-	Protein involved in initiation of plasmid replication
NPANDNHF_01398	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPANDNHF_01399	2.79e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPANDNHF_01400	8.13e-121	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NPANDNHF_01401	1.23e-85	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NPANDNHF_01402	6.81e-195	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NPANDNHF_01403	1.41e-65	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
NPANDNHF_01404	3.51e-184	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NPANDNHF_01405	4.55e-20	-	-	-	-	-	-	-	-
NPANDNHF_01406	5.62e-186	XK27_08315	-	-	M	-	-	-	Sulfatase
NPANDNHF_01407	1.04e-223	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NPANDNHF_01408	9.92e-160	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPANDNHF_01409	2.07e-213	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NPANDNHF_01410	1.15e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPANDNHF_01411	4.28e-222	-	-	-	M	-	-	-	Choline/ethanolamine kinase
NPANDNHF_01412	1.25e-108	-	-	-	M	-	-	-	Nucleotidyl transferase
NPANDNHF_01413	4.51e-198	-	-	-	M	-	-	-	Belongs to the BCCT transporter (TC 2.A.15) family
NPANDNHF_01414	2.45e-66	-	-	-	S	-	-	-	peptidoglycan catabolic process
NPANDNHF_01415	3.81e-228	XK27_08315	-	-	M	-	-	-	Sulfatase
NPANDNHF_01417	7.7e-213	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NPANDNHF_01418	1.2e-315	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NPANDNHF_01419	6.83e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
NPANDNHF_01420	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NPANDNHF_01421	1.87e-80	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
NPANDNHF_01422	4.18e-107	pncA	-	-	Q	-	-	-	isochorismatase
NPANDNHF_01423	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NPANDNHF_01424	3.62e-133	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NPANDNHF_01425	6.68e-219	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NPANDNHF_01426	1.7e-55	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NPANDNHF_01427	5.18e-207	-	-	-	C	-	-	-	Luciferase-like monooxygenase
NPANDNHF_01428	4.46e-86	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NPANDNHF_01429	6.89e-148	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NPANDNHF_01430	9.17e-98	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
NPANDNHF_01431	7.36e-77	-	-	-	EG	-	-	-	EamA-like transporter family
NPANDNHF_01432	2.26e-148	ydbI	-	-	K	-	-	-	AI-2E family transporter
NPANDNHF_01433	1.1e-217	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NPANDNHF_01434	8.68e-159	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPANDNHF_01435	6.14e-08	-	-	-	S	-	-	-	zinc-ribbon domain
NPANDNHF_01438	4.13e-153	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
NPANDNHF_01439	1.78e-163	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NPANDNHF_01440	6.33e-25	-	-	-	-	-	-	-	-
NPANDNHF_01441	3.08e-133	-	-	-	E	-	-	-	AzlC protein
NPANDNHF_01442	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
NPANDNHF_01443	2.12e-82	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NPANDNHF_01444	1.44e-23	-	-	-	-	-	-	-	-
NPANDNHF_01445	3.63e-53	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
NPANDNHF_01446	4.36e-29	-	-	-	-	-	-	-	-
NPANDNHF_01447	5.04e-118	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NPANDNHF_01448	1.77e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
NPANDNHF_01449	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NPANDNHF_01450	9.59e-104	-	-	-	S	-	-	-	Putative threonine/serine exporter
NPANDNHF_01451	1.97e-64	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NPANDNHF_01452	1.96e-155	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NPANDNHF_01453	1.48e-110	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NPANDNHF_01454	3.2e-45	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NPANDNHF_01455	2.19e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPANDNHF_01456	8.32e-29	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPANDNHF_01457	9.35e-84	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
NPANDNHF_01459	1.09e-68	ccl	-	-	S	-	-	-	QueT transporter
NPANDNHF_01460	7.29e-46	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
NPANDNHF_01461	6.37e-131	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NPANDNHF_01462	6.37e-220	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPANDNHF_01463	7.48e-122	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPANDNHF_01464	3.36e-112	-	-	-	S	-	-	-	Alpha beta hydrolase
NPANDNHF_01465	2.95e-58	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPANDNHF_01466	1.97e-174	-	-	-	V	-	-	-	MatE
NPANDNHF_01467	8.03e-199	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NPANDNHF_01468	5.65e-92	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NPANDNHF_01469	7.95e-126	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NPANDNHF_01470	1.13e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NPANDNHF_01471	3.67e-101	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NPANDNHF_01472	3.91e-33	-	-	-	-	-	-	-	-
NPANDNHF_01473	6.84e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
NPANDNHF_01474	4.36e-102	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NPANDNHF_01475	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NPANDNHF_01476	1.68e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPANDNHF_01477	6.14e-269	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NPANDNHF_01478	1e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NPANDNHF_01479	1.03e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
NPANDNHF_01480	3e-121	-	-	-	-	-	-	-	-
NPANDNHF_01481	7.25e-17	-	-	-	-	-	-	-	-
NPANDNHF_01482	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_01483	8.41e-127	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPANDNHF_01484	4.89e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPANDNHF_01485	5.39e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NPANDNHF_01486	5.79e-240	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NPANDNHF_01487	1.4e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NPANDNHF_01488	1.35e-85	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NPANDNHF_01489	4.77e-54	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NPANDNHF_01490	2.82e-77	-	-	-	K	-	-	-	rpiR family
NPANDNHF_01492	4.93e-217	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPANDNHF_01493	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NPANDNHF_01494	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPANDNHF_01495	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NPANDNHF_01496	3.85e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPANDNHF_01497	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPANDNHF_01498	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPANDNHF_01499	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPANDNHF_01500	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPANDNHF_01501	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPANDNHF_01502	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NPANDNHF_01503	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPANDNHF_01504	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPANDNHF_01505	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPANDNHF_01506	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPANDNHF_01507	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPANDNHF_01508	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPANDNHF_01509	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPANDNHF_01510	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPANDNHF_01511	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPANDNHF_01512	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NPANDNHF_01513	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NPANDNHF_01514	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPANDNHF_01515	8.94e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPANDNHF_01516	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPANDNHF_01517	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NPANDNHF_01518	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPANDNHF_01519	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPANDNHF_01520	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPANDNHF_01521	6.34e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NPANDNHF_01522	7.93e-128	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPANDNHF_01523	2.51e-139	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPANDNHF_01524	1.08e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPANDNHF_01525	6.22e-160	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPANDNHF_01526	1.04e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPANDNHF_01527	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NPANDNHF_01529	5.67e-307	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NPANDNHF_01530	2.27e-86	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NPANDNHF_01531	5.79e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NPANDNHF_01532	1.05e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NPANDNHF_01533	1.1e-95	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NPANDNHF_01534	8.13e-42	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
NPANDNHF_01535	1.53e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NPANDNHF_01536	3.6e-161	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NPANDNHF_01537	2.94e-117	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NPANDNHF_01538	1.12e-95	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NPANDNHF_01539	9.27e-46	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
NPANDNHF_01540	2.24e-138	potE	-	-	E	-	-	-	Amino Acid
NPANDNHF_01541	1e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
NPANDNHF_01542	6.03e-221	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPANDNHF_01543	5.76e-96	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPANDNHF_01544	9.77e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
NPANDNHF_01545	6.49e-79	-	-	-	-	-	-	-	-
NPANDNHF_01546	0.0	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NPANDNHF_01547	5.03e-37	xerD_2	-	-	L	-	-	-	Phage integrase family
NPANDNHF_01550	4.75e-215	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NPANDNHF_01551	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
NPANDNHF_01552	2.41e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
NPANDNHF_01553	6.68e-282	-	-	-	L	-	-	-	Probable transposase
NPANDNHF_01557	3.57e-68	repB	-	-	L	-	-	-	Initiator Replication protein
NPANDNHF_01558	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
NPANDNHF_01559	1.76e-18	-	-	-	M	-	-	-	hydrolase, family 25
NPANDNHF_01560	1.33e-104	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
NPANDNHF_01561	2.86e-113	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NPANDNHF_01562	4.86e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NPANDNHF_01563	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
NPANDNHF_01564	4.91e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NPANDNHF_01565	7.31e-164	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPANDNHF_01566	1.82e-49	-	-	-	-	-	-	-	-
NPANDNHF_01567	1.9e-118	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
NPANDNHF_01568	6.6e-76	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPANDNHF_01569	5.19e-199	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPANDNHF_01570	3.59e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPANDNHF_01571	1.15e-137	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPANDNHF_01573	2.07e-141	csrR	-	-	K	-	-	-	response regulator
NPANDNHF_01574	1.26e-217	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NPANDNHF_01575	2.4e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPANDNHF_01576	1.6e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NPANDNHF_01577	9.56e-170	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NPANDNHF_01578	4.27e-143	-	-	-	-	-	-	-	-
NPANDNHF_01579	1.14e-147	-	-	-	-	-	-	-	-
NPANDNHF_01580	1.45e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
NPANDNHF_01581	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPANDNHF_01582	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NPANDNHF_01583	1.45e-46	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPANDNHF_01584	3.32e-133	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPANDNHF_01585	2.31e-181	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPANDNHF_01586	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPANDNHF_01587	5.41e-105	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NPANDNHF_01588	4.44e-154	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NPANDNHF_01589	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NPANDNHF_01590	2.89e-236	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NPANDNHF_01591	2.59e-106	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPANDNHF_01592	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
NPANDNHF_01593	3.98e-36	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
NPANDNHF_01594	2.28e-118	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NPANDNHF_01595	2.16e-58	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
NPANDNHF_01596	1.31e-88	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
NPANDNHF_01598	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NPANDNHF_01599	1.8e-49	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPANDNHF_01600	9.08e-90	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
NPANDNHF_01601	1.74e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NPANDNHF_01602	1.59e-200	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NPANDNHF_01603	2.92e-60	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NPANDNHF_01604	6.17e-24	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NPANDNHF_01605	4.29e-141	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPANDNHF_01606	5.45e-258	ynbB	-	-	P	-	-	-	aluminum resistance
NPANDNHF_01607	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
NPANDNHF_01608	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NPANDNHF_01610	4.32e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPANDNHF_01611	5.83e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
NPANDNHF_01612	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NPANDNHF_01613	2.03e-105	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPANDNHF_01614	4.05e-134	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPANDNHF_01615	7.84e-132	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NPANDNHF_01616	2.38e-194	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NPANDNHF_01617	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPANDNHF_01618	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPANDNHF_01619	1.16e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NPANDNHF_01620	8.77e-217	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NPANDNHF_01621	9.53e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NPANDNHF_01622	2.24e-34	ylxQ	-	-	J	-	-	-	ribosomal protein
NPANDNHF_01623	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPANDNHF_01624	6.33e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPANDNHF_01625	1.74e-153	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPANDNHF_01626	1.97e-119	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NPANDNHF_01627	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPANDNHF_01628	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPANDNHF_01629	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NPANDNHF_01630	4.04e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPANDNHF_01631	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPANDNHF_01633	4.96e-257	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NPANDNHF_01634	7.44e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_01635	1.83e-41	-	-	-	-	-	-	-	-
NPANDNHF_01636	1.77e-139	ampC	-	-	V	-	-	-	Beta-lactamase
NPANDNHF_01637	1.89e-140	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
NPANDNHF_01638	2.09e-277	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
NPANDNHF_01639	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NPANDNHF_01640	1.04e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPANDNHF_01641	7.51e-114	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPANDNHF_01642	5.45e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPANDNHF_01643	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPANDNHF_01644	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NPANDNHF_01645	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPANDNHF_01646	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPANDNHF_01647	2.82e-74	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPANDNHF_01648	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPANDNHF_01649	1.9e-180	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPANDNHF_01650	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPANDNHF_01651	1.78e-69	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NPANDNHF_01652	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NPANDNHF_01653	1.03e-260	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPANDNHF_01654	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NPANDNHF_01655	6.55e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NPANDNHF_01656	6.63e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NPANDNHF_01657	2.21e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NPANDNHF_01658	9.86e-36	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
NPANDNHF_01659	1.09e-119	-	-	-	M	-	-	-	Phosphotransferase enzyme family
NPANDNHF_01660	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NPANDNHF_01661	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPANDNHF_01662	1.49e-110	-	-	-	L	ko:K07496	-	ko00000	Transposase, IS605 OrfB family
NPANDNHF_01663	3.88e-71	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
NPANDNHF_01664	4.27e-39	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
NPANDNHF_01665	1.4e-95	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
NPANDNHF_01677	1.42e-39	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
NPANDNHF_01679	2.37e-29	-	-	-	S	-	-	-	PIN domain
NPANDNHF_01680	1.64e-06	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
NPANDNHF_01681	2.61e-09	-	-	-	-	-	-	-	-
NPANDNHF_01682	8.14e-94	-	-	-	DM	-	-	-	Glucan-binding protein C
NPANDNHF_01685	2.02e-135	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPANDNHF_01686	1.63e-06	-	-	-	S	-	-	-	Fic/DOC family
NPANDNHF_01688	1.81e-86	-	-	-	D	-	-	-	nuclear chromosome segregation
NPANDNHF_01689	2.08e-08	-	-	-	K	-	-	-	sequence-specific DNA binding
NPANDNHF_01690	1.51e-37	-	-	-	S	-	-	-	Fic/DOC family
NPANDNHF_01691	1.26e-53	-	-	-	S	-	-	-	Fic/DOC family
NPANDNHF_01694	1.44e-37	-	-	-	L	-	-	-	four-way junction helicase activity
NPANDNHF_01698	4.52e-05	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
NPANDNHF_01709	2.57e-13	-	-	-	S	-	-	-	Arc-like DNA binding domain
NPANDNHF_01710	2.46e-14	-	-	-	-	-	-	-	-
NPANDNHF_01711	7.27e-17	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPANDNHF_01712	5.32e-18	-	-	-	-	-	-	-	-
NPANDNHF_01713	1.07e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
NPANDNHF_01714	3.17e-174	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPANDNHF_01715	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NPANDNHF_01716	3.32e-64	-	-	-	S	-	-	-	VIT family
NPANDNHF_01717	3.74e-303	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NPANDNHF_01718	1.15e-53	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NPANDNHF_01719	3.98e-182	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPANDNHF_01720	9.15e-181	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NPANDNHF_01721	1.5e-147	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NPANDNHF_01722	1.56e-281	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
NPANDNHF_01723	7.13e-35	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPANDNHF_01724	1.1e-172	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NPANDNHF_01725	6.54e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPANDNHF_01726	9.44e-82	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
NPANDNHF_01727	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NPANDNHF_01728	1.48e-173	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
NPANDNHF_01729	1.93e-106	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
NPANDNHF_01730	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
NPANDNHF_01731	7.68e-93	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NPANDNHF_01732	1.12e-139	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
NPANDNHF_01733	2.45e-22	-	-	-	M	-	-	-	by MetaGeneAnnotator
NPANDNHF_01735	3.59e-10	-	-	-	S	-	-	-	Phage minor structural protein GP20
NPANDNHF_01739	1.69e-36	-	-	-	S	-	-	-	Phage minor capsid protein 2
NPANDNHF_01740	3.07e-125	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
NPANDNHF_01741	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NPANDNHF_01742	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
NPANDNHF_01743	5.24e-91	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NPANDNHF_01749	1.88e-62	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NPANDNHF_01750	5.21e-70	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NPANDNHF_01759	5.15e-114	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NPANDNHF_01760	4.81e-19	-	-	-	-	-	-	-	-
NPANDNHF_01762	1.9e-235	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPANDNHF_01763	1.32e-102	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NPANDNHF_01767	6.67e-43	-	-	-	P	-	-	-	Heavy-metal-associated domain
NPANDNHF_01776	1.19e-89	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NPANDNHF_01777	6.77e-150	-	-	-	L	-	-	-	Phage integrase family
NPANDNHF_01779	5.36e-71	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPANDNHF_01780	3.76e-18	-	-	-	S	-	-	-	HNH endonuclease
NPANDNHF_01781	6.65e-13	-	-	-	-	-	-	-	-
NPANDNHF_01782	1.84e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
NPANDNHF_01786	3.59e-20	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
NPANDNHF_01788	8.2e-158	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
NPANDNHF_01789	5.04e-49	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
NPANDNHF_01790	4.03e-119	-	-	-	S	-	-	-	Putative HNHc nuclease
NPANDNHF_01791	3.93e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
NPANDNHF_01792	2.98e-91	-	-	-	S	-	-	-	AAA domain
NPANDNHF_01800	6.38e-51	-	-	-	S	-	-	-	ORF6C domain
NPANDNHF_01801	1.89e-18	-	-	-	-	-	-	-	-
NPANDNHF_01802	1.12e-32	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NPANDNHF_01804	1.44e-15	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
NPANDNHF_01806	5.42e-146	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NPANDNHF_01807	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPANDNHF_01808	8.95e-50	-	-	-	S	-	-	-	repeat protein
NPANDNHF_01809	5.91e-129	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
NPANDNHF_01810	4.96e-88	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NPANDNHF_01811	4.97e-42	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NPANDNHF_01812	1.1e-109	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NPANDNHF_01813	1.46e-86	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	RAMP superfamily
NPANDNHF_01814	6.18e-82	-	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
NPANDNHF_01815	1.34e-88	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
NPANDNHF_01816	6.4e-43	-	-	-	L	ko:K19138	-	ko00000,ko02048	Pfam:DUF310
NPANDNHF_01817	3.15e-252	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
NPANDNHF_01818	3.35e-42	-	-	-	S	-	-	-	Pfam:DUF2276
NPANDNHF_01819	4.46e-193	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
NPANDNHF_01820	7.75e-256	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
NPANDNHF_01821	1.42e-264	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPANDNHF_01822	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPANDNHF_01823	9.75e-107	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NPANDNHF_01824	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPANDNHF_01825	8.88e-171	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPANDNHF_01826	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NPANDNHF_01827	3.97e-69	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NPANDNHF_01828	5.31e-100	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NPANDNHF_01830	1.24e-72	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPANDNHF_01831	7.86e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPANDNHF_01832	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_01833	1.45e-167	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPANDNHF_01834	3.74e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPANDNHF_01835	2.69e-142	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPANDNHF_01836	1.91e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NPANDNHF_01838	7.61e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NPANDNHF_01839	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NPANDNHF_01840	2.08e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPANDNHF_01843	7.62e-127	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NPANDNHF_01844	1.49e-107	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
NPANDNHF_01845	2.3e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NPANDNHF_01846	4.35e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPANDNHF_01847	3.63e-101	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPANDNHF_01848	3.11e-108	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPANDNHF_01849	5.71e-72	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NPANDNHF_01850	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NPANDNHF_01851	7.4e-180	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NPANDNHF_01852	1.35e-46	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NPANDNHF_01853	2.99e-274	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NPANDNHF_01854	6.38e-120	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NPANDNHF_01855	3.59e-156	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NPANDNHF_01856	6.23e-170	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NPANDNHF_01857	1.64e-142	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPANDNHF_01858	8.38e-133	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NPANDNHF_01859	4.97e-186	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NPANDNHF_01860	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NPANDNHF_01861	2.95e-62	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NPANDNHF_01862	1.13e-36	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
NPANDNHF_01864	2.63e-113	-	-	-	L	-	-	-	HNH nucleases
NPANDNHF_01865	1.05e-107	-	-	-	L	-	-	-	Phage terminase, small subunit
NPANDNHF_01866	0.0	-	-	-	S	-	-	-	Phage Terminase
NPANDNHF_01868	1.91e-261	-	-	-	S	-	-	-	Phage portal protein
NPANDNHF_01869	2.97e-152	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
NPANDNHF_01870	7.81e-282	-	-	-	S	-	-	-	Phage capsid family
NPANDNHF_01871	6.22e-29	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NPANDNHF_01872	2.22e-78	-	-	-	S	-	-	-	Phage head-tail joining protein
NPANDNHF_01873	4.62e-71	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NPANDNHF_01874	1.03e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
NPANDNHF_01875	2.2e-158	-	-	-	S	-	-	-	Phage tail tube protein
NPANDNHF_01876	1.58e-73	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
NPANDNHF_01878	3.21e-118	-	-	-	M	-	-	-	by MetaGeneAnnotator
NPANDNHF_01880	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
NPANDNHF_01881	3.46e-183	-	-	-	S	-	-	-	Phage tail protein
NPANDNHF_01882	0.0	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
NPANDNHF_01886	1.15e-14	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
NPANDNHF_01888	1.15e-26	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NPANDNHF_01889	2.13e-142	-	-	-	M	-	-	-	lysozyme activity
NPANDNHF_01890	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NPANDNHF_01891	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPANDNHF_01892	7.62e-147	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPANDNHF_01893	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPANDNHF_01894	0.00027	-	-	-	S	-	-	-	Tetratricopeptide repeat
NPANDNHF_01895	6.83e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPANDNHF_01896	2.37e-246	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPANDNHF_01897	3.67e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPANDNHF_01898	3.87e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPANDNHF_01899	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPANDNHF_01900	1.47e-30	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NPANDNHF_01901	3.51e-33	-	-	-	-	-	-	-	-
NPANDNHF_01902	3.2e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPANDNHF_01903	2.52e-21	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
NPANDNHF_01904	3.57e-33	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NPANDNHF_01905	4.29e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NPANDNHF_01906	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NPANDNHF_01907	1.8e-186	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
NPANDNHF_01908	3.18e-146	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
NPANDNHF_01909	2.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
NPANDNHF_01910	8.07e-124	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NPANDNHF_01911	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NPANDNHF_01912	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NPANDNHF_01913	8.69e-95	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NPANDNHF_01914	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPANDNHF_01915	1.04e-166	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NPANDNHF_01916	3.01e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NPANDNHF_01917	1.85e-40	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPANDNHF_01918	4.77e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPANDNHF_01919	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPANDNHF_01920	1.24e-282	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPANDNHF_01921	2.83e-174	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NPANDNHF_01922	6.95e-96	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPANDNHF_01923	8.15e-293	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NPANDNHF_01924	3.23e-201	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NPANDNHF_01925	1.59e-137	-	-	-	S	-	-	-	Acyltransferase family
NPANDNHF_01926	4.15e-244	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPANDNHF_01927	7.39e-156	-	-	-	K	-	-	-	LysR substrate binding domain
NPANDNHF_01929	6.94e-28	-	-	-	-	-	-	-	-
NPANDNHF_01930	5.27e-72	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NPANDNHF_01931	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NPANDNHF_01936	3.41e-166	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NPANDNHF_01937	5.35e-235	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPANDNHF_01938	1.94e-199	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NPANDNHF_01939	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NPANDNHF_01940	1.74e-151	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPANDNHF_01942	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NPANDNHF_01943	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPANDNHF_01944	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPANDNHF_01945	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPANDNHF_01946	1.13e-29	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
NPANDNHF_01947	2.07e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPANDNHF_01948	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPANDNHF_01949	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPANDNHF_01950	4.67e-117	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NPANDNHF_01951	3.16e-105	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
NPANDNHF_01952	1.21e-145	vanR	-	-	K	-	-	-	response regulator
NPANDNHF_01953	7.5e-191	hpk31	-	-	T	-	-	-	Histidine kinase
NPANDNHF_01954	2.24e-110	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NPANDNHF_01955	6.8e-189	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NPANDNHF_01956	1.57e-277	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPANDNHF_01957	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_01958	1.78e-43	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPANDNHF_01959	9.3e-280	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NPANDNHF_01960	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NPANDNHF_01961	1.29e-11	-	-	-	-	-	-	-	-
NPANDNHF_01962	5.29e-59	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
NPANDNHF_01963	2.39e-67	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
NPANDNHF_01964	1.63e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NPANDNHF_01965	7.19e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NPANDNHF_01967	0.0	-	-	-	L	-	-	-	DNA helicase
NPANDNHF_01968	2.75e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPANDNHF_01969	2.82e-217	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NPANDNHF_01970	2.78e-129	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NPANDNHF_01971	5.23e-104	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NPANDNHF_01972	3.66e-130	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NPANDNHF_01973	6.06e-39	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NPANDNHF_01974	2.97e-54	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
NPANDNHF_01975	1.02e-188	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NPANDNHF_01976	4.57e-162	-	-	-	-	-	-	-	-
NPANDNHF_01977	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPANDNHF_01978	9.88e-131	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NPANDNHF_01979	4.87e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPANDNHF_01980	9.3e-170	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPANDNHF_01981	1.9e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NPANDNHF_01982	1.9e-115	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NPANDNHF_01983	9.57e-172	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
NPANDNHF_01984	5.91e-61	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NPANDNHF_01985	2.07e-147	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NPANDNHF_01986	3.18e-195	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NPANDNHF_01987	7.84e-253	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NPANDNHF_01988	3.94e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NPANDNHF_01989	4.71e-188	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NPANDNHF_01990	9.03e-158	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPANDNHF_01991	8.86e-140	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC