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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MAKAFAOO_00001	1.89e-140	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MAKAFAOO_00002	2.09e-277	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MAKAFAOO_00003	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MAKAFAOO_00004	1.04e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MAKAFAOO_00005	3.04e-113	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MAKAFAOO_00006	1.9e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MAKAFAOO_00007	8.89e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MAKAFAOO_00008	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MAKAFAOO_00009	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAKAFAOO_00010	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MAKAFAOO_00011	2.82e-74	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAKAFAOO_00012	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MAKAFAOO_00013	3.29e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MAKAFAOO_00014	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MAKAFAOO_00015	6.22e-70	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MAKAFAOO_00016	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MAKAFAOO_00017	2.53e-261	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAKAFAOO_00018	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MAKAFAOO_00019	6.55e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MAKAFAOO_00020	6.63e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MAKAFAOO_00021	2.21e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MAKAFAOO_00022	9.86e-36	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MAKAFAOO_00023	1.54e-119	-	-	-	M	-	-	-	Phosphotransferase enzyme family
MAKAFAOO_00024	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MAKAFAOO_00025	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MAKAFAOO_00026	1.32e-153	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MAKAFAOO_00027	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MAKAFAOO_00028	1.55e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAKAFAOO_00029	1.25e-192	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MAKAFAOO_00030	1.11e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MAKAFAOO_00031	8.54e-240	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MAKAFAOO_00032	3.24e-144	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MAKAFAOO_00033	9.24e-75	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MAKAFAOO_00034	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MAKAFAOO_00035	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MAKAFAOO_00036	2.1e-303	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MAKAFAOO_00037	2.21e-305	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MAKAFAOO_00038	6.25e-180	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MAKAFAOO_00039	9.72e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAKAFAOO_00040	7.23e-130	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MAKAFAOO_00041	4.65e-286	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MAKAFAOO_00042	4.55e-187	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MAKAFAOO_00043	4.33e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MAKAFAOO_00044	9.04e-263	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MAKAFAOO_00045	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MAKAFAOO_00046	1.99e-37	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MAKAFAOO_00047	1.31e-73	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MAKAFAOO_00048	2.74e-145	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MAKAFAOO_00049	2.19e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MAKAFAOO_00050	1.24e-250	-	-	-	E	ko:K03294	-	ko00000	amino acid
MAKAFAOO_00051	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MAKAFAOO_00052	9.08e-254	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKAFAOO_00055	7.93e-113	-	-	-	S	-	-	-	AAA domain
MAKAFAOO_00056	1.08e-23	-	-	-	-	-	-	-	-
MAKAFAOO_00058	5.82e-27	-	-	-	K	-	-	-	Helix-turn-helix domain
MAKAFAOO_00062	3.32e-10	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MAKAFAOO_00063	2.73e-154	-	-	-	K	-	-	-	Transcriptional regulator
MAKAFAOO_00069	4.07e-96	-	-	-	S	-	-	-	Siphovirus Gp157
MAKAFAOO_00070	5.48e-315	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAKAFAOO_00071	4.39e-149	-	-	-	L	-	-	-	AAA domain
MAKAFAOO_00072	2.44e-110	-	-	-	-	-	-	-	-
MAKAFAOO_00073	1.05e-179	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
MAKAFAOO_00074	5.43e-294	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
MAKAFAOO_00075	1.22e-64	-	-	-	S	-	-	-	VRR_NUC
MAKAFAOO_00080	7.97e-37	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
MAKAFAOO_00082	6.41e-56	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
MAKAFAOO_00083	7.42e-243	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
MAKAFAOO_00084	1.23e-131	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MAKAFAOO_00085	3.84e-86	-	-	-	S	-	-	-	Phage Mu protein F like protein
MAKAFAOO_00088	1.01e-15	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
MAKAFAOO_00089	4.09e-124	-	-	-	-	-	-	-	-
MAKAFAOO_00090	7.22e-44	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MAKAFAOO_00091	4.82e-14	-	-	-	-	-	-	-	-
MAKAFAOO_00092	4.94e-17	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MAKAFAOO_00093	5.45e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
MAKAFAOO_00097	8.27e-133	-	-	-	D	-	-	-	Phage tail tape measure protein
MAKAFAOO_00098	3.48e-74	-	-	-	S	-	-	-	phage tail
MAKAFAOO_00099	2.85e-88	-	-	-	M	-	-	-	Prophage endopeptidase tail
MAKAFAOO_00100	8.11e-260	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MAKAFAOO_00101	1.27e-52	-	-	-	S	-	-	-	Bacteriophage holin family
MAKAFAOO_00102	9.14e-149	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
MAKAFAOO_00103	9.87e-158	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MAKAFAOO_00104	1.67e-61	-	-	-	-	-	-	-	-
MAKAFAOO_00105	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MAKAFAOO_00106	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MAKAFAOO_00107	7.62e-147	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAKAFAOO_00108	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAKAFAOO_00109	0.000864	-	-	-	S	-	-	-	Tetratricopeptide repeat
MAKAFAOO_00110	6.83e-274	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MAKAFAOO_00111	9.64e-246	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MAKAFAOO_00112	3.54e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MAKAFAOO_00113	3.87e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MAKAFAOO_00114	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAKAFAOO_00115	1.47e-30	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MAKAFAOO_00116	3.51e-33	-	-	-	-	-	-	-	-
MAKAFAOO_00117	7.87e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MAKAFAOO_00118	1.31e-21	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
MAKAFAOO_00119	1.45e-32	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MAKAFAOO_00120	4.29e-96	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
MAKAFAOO_00121	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MAKAFAOO_00122	1.55e-187	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MAKAFAOO_00123	3.18e-146	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MAKAFAOO_00124	8.37e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MAKAFAOO_00125	8.72e-126	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MAKAFAOO_00126	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MAKAFAOO_00127	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MAKAFAOO_00128	6.12e-95	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MAKAFAOO_00129	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MAKAFAOO_00130	1.81e-167	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MAKAFAOO_00131	8.62e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MAKAFAOO_00132	3.19e-41	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAKAFAOO_00133	4.77e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAKAFAOO_00134	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAKAFAOO_00135	3.04e-283	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MAKAFAOO_00136	1.15e-173	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MAKAFAOO_00137	6.95e-96	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MAKAFAOO_00138	4.88e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MAKAFAOO_00139	2.4e-203	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MAKAFAOO_00140	1.59e-137	-	-	-	S	-	-	-	Acyltransferase family
MAKAFAOO_00141	1.19e-243	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAKAFAOO_00142	7.39e-156	-	-	-	K	-	-	-	LysR substrate binding domain
MAKAFAOO_00144	6.94e-28	-	-	-	-	-	-	-	-
MAKAFAOO_00145	5.27e-72	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MAKAFAOO_00146	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MAKAFAOO_00147	2.95e-62	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MAKAFAOO_00148	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MAKAFAOO_00149	2.49e-186	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MAKAFAOO_00150	2.39e-132	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MAKAFAOO_00151	4.7e-142	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MAKAFAOO_00152	2.53e-169	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MAKAFAOO_00153	6.87e-154	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MAKAFAOO_00154	6.38e-120	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
MAKAFAOO_00155	1.86e-275	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MAKAFAOO_00156	1.55e-45	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MAKAFAOO_00157	1.22e-178	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MAKAFAOO_00158	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MAKAFAOO_00159	7.26e-72	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MAKAFAOO_00160	1.71e-105	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MAKAFAOO_00161	6.01e-100	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAKAFAOO_00162	4.35e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MAKAFAOO_00163	9.62e-116	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MAKAFAOO_00164	1.49e-107	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MAKAFAOO_00165	3.08e-126	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MAKAFAOO_00168	8.44e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MAKAFAOO_00169	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MAKAFAOO_00170	1.08e-74	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MAKAFAOO_00172	7.71e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MAKAFAOO_00173	2.69e-142	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MAKAFAOO_00174	4.56e-137	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MAKAFAOO_00175	2.52e-168	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MAKAFAOO_00176	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_00177	1.12e-199	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MAKAFAOO_00178	2.15e-73	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MAKAFAOO_00180	2.64e-100	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MAKAFAOO_00181	1.13e-68	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
MAKAFAOO_00182	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MAKAFAOO_00183	8.88e-171	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MAKAFAOO_00184	8.28e-124	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAKAFAOO_00185	9.75e-107	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MAKAFAOO_00186	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MAKAFAOO_00187	1.42e-264	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MAKAFAOO_00188	1.91e-256	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
MAKAFAOO_00189	1.83e-162	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
MAKAFAOO_00190	4.16e-129	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MAKAFAOO_00191	1.27e-49	-	-	-	S	-	-	-	repeat protein
MAKAFAOO_00192	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MAKAFAOO_00194	4.91e-117	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKAFAOO_00195	6.2e-06	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKAFAOO_00197	1.53e-29	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	RNase_H superfamily
MAKAFAOO_00198	1.28e-17	-	-	-	-	-	-	-	-
MAKAFAOO_00199	1.13e-23	-	-	-	L	-	-	-	nuclease
MAKAFAOO_00200	1.81e-36	-	-	-	S	-	-	-	Short C-terminal domain
MAKAFAOO_00202	5.37e-43	-	-	-	E	-	-	-	Zn peptidase
MAKAFAOO_00203	2.88e-48	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAKAFAOO_00204	2.63e-12	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
MAKAFAOO_00208	2.32e-109	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAKAFAOO_00209	1.95e-88	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAKAFAOO_00210	2.8e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MAKAFAOO_00211	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MAKAFAOO_00212	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAKAFAOO_00213	1.15e-163	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MAKAFAOO_00214	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MAKAFAOO_00215	2e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAKAFAOO_00216	5.6e-17	-	-	-	-	-	-	-	-
MAKAFAOO_00217	1.76e-183	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
MAKAFAOO_00218	6.01e-55	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
MAKAFAOO_00219	6.22e-149	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MAKAFAOO_00220	2.15e-97	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MAKAFAOO_00221	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAKAFAOO_00222	7.24e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MAKAFAOO_00223	3.62e-72	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
MAKAFAOO_00224	4.45e-55	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAKAFAOO_00225	8.37e-165	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAKAFAOO_00226	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MAKAFAOO_00227	1.07e-256	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MAKAFAOO_00228	1.29e-141	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MAKAFAOO_00229	1.48e-237	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MAKAFAOO_00230	1.5e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MAKAFAOO_00231	1.43e-112	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MAKAFAOO_00232	1.83e-172	-	-	-	K	-	-	-	Transcriptional regulator
MAKAFAOO_00233	7.65e-185	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MAKAFAOO_00234	4.04e-148	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MAKAFAOO_00235	4.96e-219	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKAFAOO_00236	3.49e-111	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MAKAFAOO_00238	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MAKAFAOO_00239	2.69e-218	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MAKAFAOO_00240	4.42e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
MAKAFAOO_00241	2.53e-35	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
MAKAFAOO_00242	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MAKAFAOO_00243	1.52e-51	-	-	-	-	-	-	-	-
MAKAFAOO_00247	8.31e-185	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MAKAFAOO_00248	5.6e-97	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MAKAFAOO_00249	3.3e-131	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MAKAFAOO_00250	1.44e-231	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MAKAFAOO_00251	2.49e-89	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
MAKAFAOO_00252	4.93e-174	-	-	-	EG	-	-	-	EamA-like transporter family
MAKAFAOO_00253	3.9e-190	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MAKAFAOO_00254	3.14e-256	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MAKAFAOO_00255	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MAKAFAOO_00256	2.06e-172	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MAKAFAOO_00257	6.67e-221	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MAKAFAOO_00258	4.02e-164	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MAKAFAOO_00259	1.47e-105	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MAKAFAOO_00261	8.87e-120	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MAKAFAOO_00262	3.16e-199	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MAKAFAOO_00263	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MAKAFAOO_00264	2.3e-255	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MAKAFAOO_00265	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MAKAFAOO_00266	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MAKAFAOO_00267	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MAKAFAOO_00268	1.19e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MAKAFAOO_00269	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MAKAFAOO_00271	7.56e-52	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MAKAFAOO_00272	1.96e-106	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MAKAFAOO_00273	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAKAFAOO_00274	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAKAFAOO_00275	7.68e-253	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MAKAFAOO_00276	2.07e-52	-	-	-	K	-	-	-	Transcriptional regulator
MAKAFAOO_00277	4.82e-147	-	-	-	S	-	-	-	EDD domain protein, DegV family
MAKAFAOO_00278	3.9e-91	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
MAKAFAOO_00279	4.18e-35	-	-	-	M	-	-	-	Rib/alpha-like repeat
MAKAFAOO_00280	1.49e-56	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
MAKAFAOO_00281	3.27e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
MAKAFAOO_00282	1.47e-51	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKAFAOO_00283	6.31e-75	napB	-	-	K	-	-	-	transcriptional
MAKAFAOO_00284	3.21e-89	mleR	-	-	K	-	-	-	LysR family
MAKAFAOO_00285	2.39e-313	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
MAKAFAOO_00286	4.34e-162	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
MAKAFAOO_00287	2.31e-81	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MAKAFAOO_00288	2.58e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MAKAFAOO_00289	3.22e-95	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MAKAFAOO_00290	7.39e-253	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MAKAFAOO_00291	1.72e-50	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MAKAFAOO_00292	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MAKAFAOO_00293	6.48e-123	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MAKAFAOO_00294	2.08e-147	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MAKAFAOO_00295	4.86e-118	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAKAFAOO_00296	1.27e-228	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MAKAFAOO_00298	1.96e-54	-	-	-	-	-	-	-	-
MAKAFAOO_00299	2.18e-06	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MAKAFAOO_00300	7.96e-263	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MAKAFAOO_00301	1.46e-277	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MAKAFAOO_00302	2.04e-45	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MAKAFAOO_00303	3.59e-273	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MAKAFAOO_00304	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MAKAFAOO_00305	9.65e-209	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MAKAFAOO_00306	3.9e-157	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
MAKAFAOO_00307	7.4e-243	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
MAKAFAOO_00308	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MAKAFAOO_00309	1.14e-213	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MAKAFAOO_00310	1.86e-31	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
MAKAFAOO_00311	1.32e-161	mocA	-	-	S	-	-	-	Oxidoreductase
MAKAFAOO_00312	5.66e-201	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MAKAFAOO_00315	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MAKAFAOO_00316	1.64e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKAFAOO_00317	1.22e-270	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
MAKAFAOO_00318	1.92e-95	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MAKAFAOO_00319	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MAKAFAOO_00320	7.42e-109	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MAKAFAOO_00321	0.0	-	-	-	E	-	-	-	Amino acid permease
MAKAFAOO_00322	4.96e-229	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
MAKAFAOO_00323	1.35e-213	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MAKAFAOO_00324	2.43e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
MAKAFAOO_00325	1.31e-154	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
MAKAFAOO_00326	1.39e-151	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
MAKAFAOO_00327	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MAKAFAOO_00328	1.33e-67	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
MAKAFAOO_00329	2.04e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MAKAFAOO_00330	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MAKAFAOO_00331	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MAKAFAOO_00332	6.29e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
MAKAFAOO_00333	8.07e-120	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MAKAFAOO_00335	4.87e-26	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKAFAOO_00337	2.61e-52	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
MAKAFAOO_00338	2.76e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MAKAFAOO_00339	2.35e-85	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MAKAFAOO_00342	3.71e-138	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
MAKAFAOO_00343	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MAKAFAOO_00344	2.5e-59	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MAKAFAOO_00345	9.15e-68	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MAKAFAOO_00346	4.46e-70	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
MAKAFAOO_00347	1.56e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MAKAFAOO_00348	1.49e-44	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MAKAFAOO_00349	1.99e-96	azlC	-	-	E	-	-	-	branched-chain amino acid
MAKAFAOO_00350	1.13e-75	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MAKAFAOO_00351	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MAKAFAOO_00352	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MAKAFAOO_00353	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MAKAFAOO_00354	1.43e-238	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
MAKAFAOO_00355	1.85e-96	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MAKAFAOO_00356	5.69e-142	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MAKAFAOO_00358	2.04e-264	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MAKAFAOO_00359	5.79e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKAFAOO_00360	1.8e-145	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
MAKAFAOO_00361	4.78e-196	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
MAKAFAOO_00362	4.9e-89	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
MAKAFAOO_00363	1.7e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
MAKAFAOO_00364	2.17e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MAKAFAOO_00365	2.67e-218	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MAKAFAOO_00366	3.33e-259	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
MAKAFAOO_00367	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MAKAFAOO_00368	4.12e-236	noxE	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MAKAFAOO_00369	3.28e-61	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MAKAFAOO_00371	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKAFAOO_00372	2.37e-127	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_00373	1.36e-121	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MAKAFAOO_00374	2.64e-49	-	-	-	K	-	-	-	Transcriptional regulator
MAKAFAOO_00375	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
MAKAFAOO_00376	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MAKAFAOO_00377	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAKAFAOO_00378	8.51e-236	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
MAKAFAOO_00379	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
MAKAFAOO_00380	1.65e-123	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_00382	1.41e-51	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
MAKAFAOO_00383	2.08e-73	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MAKAFAOO_00384	1.41e-199	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MAKAFAOO_00385	4.49e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MAKAFAOO_00386	1.42e-197	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MAKAFAOO_00387	3.93e-180	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAKAFAOO_00388	2.74e-103	-	-	-	S	-	-	-	Putative threonine/serine exporter
MAKAFAOO_00389	1.97e-64	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MAKAFAOO_00390	1.96e-155	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAKAFAOO_00391	2.09e-110	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MAKAFAOO_00392	7.86e-46	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MAKAFAOO_00393	3.11e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAKAFAOO_00394	4.13e-29	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAKAFAOO_00395	1.33e-83	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MAKAFAOO_00397	1.09e-68	ccl	-	-	S	-	-	-	QueT transporter
MAKAFAOO_00398	7.29e-46	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
MAKAFAOO_00399	1.28e-130	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MAKAFAOO_00400	2.12e-218	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MAKAFAOO_00401	7.48e-122	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MAKAFAOO_00402	1.67e-112	-	-	-	S	-	-	-	Alpha beta hydrolase
MAKAFAOO_00403	1.46e-58	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MAKAFAOO_00404	3.97e-174	-	-	-	V	-	-	-	MatE
MAKAFAOO_00405	6.88e-200	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MAKAFAOO_00406	2.48e-93	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAKAFAOO_00407	2.28e-125	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MAKAFAOO_00408	1.13e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MAKAFAOO_00409	3.67e-101	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MAKAFAOO_00410	2.76e-33	-	-	-	-	-	-	-	-
MAKAFAOO_00411	6.84e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
MAKAFAOO_00412	1.44e-100	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MAKAFAOO_00413	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAKAFAOO_00414	1.68e-316	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MAKAFAOO_00415	2.15e-269	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MAKAFAOO_00416	1.73e-69	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MAKAFAOO_00417	1.03e-16	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
MAKAFAOO_00418	1.21e-120	-	-	-	-	-	-	-	-
MAKAFAOO_00419	3.89e-17	-	-	-	-	-	-	-	-
MAKAFAOO_00420	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_00421	9.76e-126	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKAFAOO_00422	4.89e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKAFAOO_00423	5.39e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKAFAOO_00424	5.79e-240	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MAKAFAOO_00425	1.4e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAKAFAOO_00426	2.77e-186	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MAKAFAOO_00427	9.33e-68	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MAKAFAOO_00428	3.74e-101	-	-	-	K	-	-	-	rpiR family
MAKAFAOO_00429	4.22e-211	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MAKAFAOO_00430	3.24e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MAKAFAOO_00431	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MAKAFAOO_00432	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MAKAFAOO_00433	3.85e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MAKAFAOO_00434	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MAKAFAOO_00435	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MAKAFAOO_00436	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MAKAFAOO_00437	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MAKAFAOO_00438	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MAKAFAOO_00439	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MAKAFAOO_00440	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MAKAFAOO_00441	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MAKAFAOO_00442	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MAKAFAOO_00443	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MAKAFAOO_00444	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAKAFAOO_00445	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MAKAFAOO_00446	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MAKAFAOO_00447	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MAKAFAOO_00448	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MAKAFAOO_00449	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MAKAFAOO_00450	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MAKAFAOO_00451	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MAKAFAOO_00452	3.44e-69	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MAKAFAOO_00453	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
MAKAFAOO_00455	5.46e-246	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MAKAFAOO_00456	1.03e-31	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MAKAFAOO_00457	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MAKAFAOO_00458	6.33e-73	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MAKAFAOO_00459	6.54e-223	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MAKAFAOO_00460	6.91e-205	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MAKAFAOO_00461	1.44e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAKAFAOO_00462	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MAKAFAOO_00463	1.21e-169	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MAKAFAOO_00464	5.31e-101	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MAKAFAOO_00465	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MAKAFAOO_00466	1.58e-205	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MAKAFAOO_00467	1.64e-121	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MAKAFAOO_00468	3.99e-72	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
MAKAFAOO_00469	4.14e-97	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MAKAFAOO_00470	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MAKAFAOO_00471	8.65e-122	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKAFAOO_00472	1.41e-115	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_00473	9.26e-138	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MAKAFAOO_00474	6.26e-123	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MAKAFAOO_00475	1.09e-195	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
MAKAFAOO_00477	2.65e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MAKAFAOO_00478	3.67e-180	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MAKAFAOO_00479	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
MAKAFAOO_00480	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MAKAFAOO_00481	3.64e-172	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MAKAFAOO_00482	4.21e-233	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAKAFAOO_00483	1.05e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MAKAFAOO_00484	2.27e-76	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MAKAFAOO_00485	6.07e-240	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MAKAFAOO_00486	4.52e-229	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MAKAFAOO_00487	1.15e-42	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MAKAFAOO_00488	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MAKAFAOO_00489	1.63e-103	ylmH	-	-	S	-	-	-	S4 domain protein
MAKAFAOO_00490	3.98e-92	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MAKAFAOO_00491	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MAKAFAOO_00492	1.84e-130	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MAKAFAOO_00493	2e-91	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MAKAFAOO_00495	1.29e-109	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MAKAFAOO_00496	1.12e-115	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
MAKAFAOO_00497	1.97e-65	-	-	-	M	-	-	-	LysM domain protein
MAKAFAOO_00498	1.38e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
MAKAFAOO_00499	2.89e-229	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MAKAFAOO_00500	3.1e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
MAKAFAOO_00501	3.29e-224	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MAKAFAOO_00502	2.28e-283	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MAKAFAOO_00503	4.28e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MAKAFAOO_00504	5.35e-182	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MAKAFAOO_00506	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MAKAFAOO_00507	9.99e-114	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
MAKAFAOO_00508	5.69e-197	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
MAKAFAOO_00509	1.8e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MAKAFAOO_00510	2.36e-74	-	-	-	-	-	-	-	-
MAKAFAOO_00511	5.36e-53	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MAKAFAOO_00512	2.22e-30	-	-	-	S	-	-	-	Cytochrome B5
MAKAFAOO_00514	4.52e-79	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MAKAFAOO_00515	2.71e-243	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAKAFAOO_00516	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MAKAFAOO_00517	5.75e-135	yueF	-	-	S	-	-	-	AI-2E family transporter
MAKAFAOO_00518	3.8e-201	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MAKAFAOO_00519	3.95e-146	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MAKAFAOO_00520	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MAKAFAOO_00521	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
MAKAFAOO_00522	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MAKAFAOO_00523	4.55e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MAKAFAOO_00524	2.91e-223	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MAKAFAOO_00525	3.62e-207	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MAKAFAOO_00526	2.44e-252	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MAKAFAOO_00527	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MAKAFAOO_00528	2.7e-130	-	-	-	G	-	-	-	MucBP domain
MAKAFAOO_00529	3.55e-31	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MAKAFAOO_00530	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MAKAFAOO_00531	1.5e-22	-	-	-	-	-	-	-	-
MAKAFAOO_00532	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MAKAFAOO_00533	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MAKAFAOO_00534	1.8e-203	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MAKAFAOO_00535	7.47e-163	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MAKAFAOO_00536	5.88e-164	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MAKAFAOO_00537	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
MAKAFAOO_00538	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MAKAFAOO_00539	8.94e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MAKAFAOO_00540	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MAKAFAOO_00541	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MAKAFAOO_00542	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MAKAFAOO_00543	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MAKAFAOO_00544	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAKAFAOO_00545	4.47e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MAKAFAOO_00546	7.93e-128	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAKAFAOO_00547	1.77e-139	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAKAFAOO_00548	3.1e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAKAFAOO_00549	6.22e-160	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MAKAFAOO_00550	7.31e-100	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MAKAFAOO_00551	2.29e-79	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MAKAFAOO_00553	2.82e-307	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MAKAFAOO_00554	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MAKAFAOO_00555	1.03e-85	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MAKAFAOO_00556	1.28e-110	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_00557	4.91e-141	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKAFAOO_00558	2.1e-41	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
MAKAFAOO_00559	8.71e-109	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MAKAFAOO_00560	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MAKAFAOO_00561	1.95e-64	-	-	-	M	-	-	-	LysM domain protein
MAKAFAOO_00562	2.18e-144	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MAKAFAOO_00563	6.69e-131	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
MAKAFAOO_00564	1.65e-72	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MAKAFAOO_00565	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MAKAFAOO_00566	4.09e-261	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MAKAFAOO_00567	1.8e-179	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MAKAFAOO_00568	2.2e-110	-	-	-	S	-	-	-	(CBS) domain
MAKAFAOO_00569	1.16e-201	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MAKAFAOO_00570	4.14e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MAKAFAOO_00571	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MAKAFAOO_00572	2.87e-174	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MAKAFAOO_00573	1.1e-42	yabO	-	-	J	-	-	-	S4 domain protein
MAKAFAOO_00574	2e-26	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MAKAFAOO_00575	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
MAKAFAOO_00576	2.59e-118	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MAKAFAOO_00577	3.54e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MAKAFAOO_00578	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAKAFAOO_00579	4.6e-167	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MAKAFAOO_00580	2.4e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MAKAFAOO_00581	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MAKAFAOO_00582	4.75e-310	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
MAKAFAOO_00583	6.42e-79	-	-	-	-	-	-	-	-
MAKAFAOO_00584	2.05e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MAKAFAOO_00585	1.93e-240	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MAKAFAOO_00586	1.33e-254	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAKAFAOO_00588	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MAKAFAOO_00589	3.27e-57	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MAKAFAOO_00590	1.8e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MAKAFAOO_00591	1.42e-109	-	-	-	F	-	-	-	glutamine amidotransferase
MAKAFAOO_00592	9.86e-261	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
MAKAFAOO_00593	1.01e-110	-	-	-	S	-	-	-	hydrolase
MAKAFAOO_00594	2.14e-132	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
MAKAFAOO_00595	1.17e-77	-	-	-	-	-	-	-	-
MAKAFAOO_00597	8.25e-26	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	PIF1-like helicase
MAKAFAOO_00599	4.91e-63	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
MAKAFAOO_00601	6.71e-110	-	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKAFAOO_00602	5.71e-152	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKAFAOO_00603	3.31e-122	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MAKAFAOO_00604	3.47e-79	ytkL	-	-	S	-	-	-	Beta-lactamase superfamily domain
MAKAFAOO_00605	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MAKAFAOO_00606	5.27e-97	-	-	-	F	-	-	-	Phosphorylase superfamily
MAKAFAOO_00607	1.82e-33	-	-	-	-	-	-	-	-
MAKAFAOO_00608	4.77e-140	dkgB	-	-	S	-	-	-	reductase
MAKAFAOO_00610	3.2e-27	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MAKAFAOO_00611	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAKAFAOO_00612	1.12e-256	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MAKAFAOO_00613	6.83e-72	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MAKAFAOO_00614	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MAKAFAOO_00615	5.12e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MAKAFAOO_00616	2.77e-234	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MAKAFAOO_00617	3.05e-20	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MAKAFAOO_00618	3.67e-224	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MAKAFAOO_00619	1.06e-212	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
MAKAFAOO_00620	2.22e-229	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MAKAFAOO_00621	3.07e-291	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
MAKAFAOO_00622	4.72e-187	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MAKAFAOO_00623	7.11e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MAKAFAOO_00624	1.96e-78	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MAKAFAOO_00625	2.52e-17	-	-	-	-	-	-	-	-
MAKAFAOO_00626	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MAKAFAOO_00627	3.25e-280	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MAKAFAOO_00628	1.2e-112	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MAKAFAOO_00629	1.91e-191	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MAKAFAOO_00630	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MAKAFAOO_00631	3.27e-57	cps3F	-	-	-	-	-	-	-
MAKAFAOO_00632	4.47e-108	-	-	-	S	-	-	-	Membrane
MAKAFAOO_00633	0.0	-	-	-	E	-	-	-	Amino acid permease
MAKAFAOO_00634	5.11e-293	cadA	-	-	P	-	-	-	P-type ATPase
MAKAFAOO_00635	2.47e-146	degV	-	-	S	-	-	-	EDD domain protein, DegV family
MAKAFAOO_00636	1.18e-188	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MAKAFAOO_00637	8.36e-70	-	-	-	F	-	-	-	glutamine amidotransferase
MAKAFAOO_00638	2.15e-34	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
MAKAFAOO_00639	6.07e-186	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MAKAFAOO_00640	6.63e-173	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MAKAFAOO_00641	1.95e-102	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MAKAFAOO_00642	1.18e-207	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
MAKAFAOO_00643	8.89e-21	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MAKAFAOO_00644	1.21e-283	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKAFAOO_00645	9.74e-159	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAKAFAOO_00646	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
MAKAFAOO_00647	3.86e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MAKAFAOO_00648	3.33e-107	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MAKAFAOO_00649	1.51e-71	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
MAKAFAOO_00650	4.07e-14	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MAKAFAOO_00651	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MAKAFAOO_00652	2.76e-87	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MAKAFAOO_00653	2.64e-308	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
MAKAFAOO_00654	1.6e-262	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MAKAFAOO_00655	1.53e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
MAKAFAOO_00656	4.19e-160	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MAKAFAOO_00657	2.94e-117	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MAKAFAOO_00658	4.83e-97	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MAKAFAOO_00659	3.01e-79	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
MAKAFAOO_00660	9.5e-179	potE	-	-	E	-	-	-	Amino Acid
MAKAFAOO_00661	3.88e-71	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MAKAFAOO_00662	5.26e-111	-	-	-	L	ko:K07496	-	ko00000	Transposase, IS605 OrfB family
MAKAFAOO_00663	3.94e-61	potE	-	-	E	-	-	-	Amino Acid
MAKAFAOO_00664	5.75e-09	-	-	-	-	-	-	-	-
MAKAFAOO_00665	1.82e-41	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAKAFAOO_00666	2.13e-227	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
MAKAFAOO_00667	4.62e-62	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
MAKAFAOO_00668	5.49e-230	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MAKAFAOO_00669	5.08e-160	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
MAKAFAOO_00670	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
MAKAFAOO_00671	1.9e-62	yulB	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MAKAFAOO_00672	3.15e-127	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
MAKAFAOO_00673	7.61e-10	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
MAKAFAOO_00674	3.19e-51	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
MAKAFAOO_00676	0.000105	-	-	-	-	-	-	-	-
MAKAFAOO_00677	7.67e-288	fusA1	-	-	J	-	-	-	elongation factor G
MAKAFAOO_00678	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MAKAFAOO_00679	5.61e-113	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MAKAFAOO_00680	3.25e-218	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MAKAFAOO_00681	3.37e-150	-	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
MAKAFAOO_00682	7.25e-234	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MAKAFAOO_00683	4.74e-48	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MAKAFAOO_00684	1.06e-51	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MAKAFAOO_00685	6.88e-78	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
MAKAFAOO_00686	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MAKAFAOO_00687	1.89e-113	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MAKAFAOO_00688	9.16e-27	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
MAKAFAOO_00691	9.27e-142	-	-	-	L	-	-	-	Initiator Replication protein
MAKAFAOO_00692	1.88e-45	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
MAKAFAOO_00693	8.88e-30	-	-	-	C	-	-	-	FMN_bind
MAKAFAOO_00694	1.26e-149	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MAKAFAOO_00695	1.46e-255	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MAKAFAOO_00696	3.41e-177	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MAKAFAOO_00697	1.92e-101	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MAKAFAOO_00698	1.16e-171	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MAKAFAOO_00699	2.9e-189	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MAKAFAOO_00700	5.2e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
MAKAFAOO_00701	1.21e-25	-	-	-	S	-	-	-	Cupredoxin-like domain
MAKAFAOO_00702	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MAKAFAOO_00703	1.28e-77	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
MAKAFAOO_00704	2.18e-72	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MAKAFAOO_00705	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAKAFAOO_00706	3.57e-276	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MAKAFAOO_00707	2.91e-252	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MAKAFAOO_00708	3.98e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAKAFAOO_00709	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MAKAFAOO_00710	6.06e-230	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MAKAFAOO_00711	1.2e-197	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MAKAFAOO_00712	3.69e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MAKAFAOO_00713	3.9e-264	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MAKAFAOO_00714	1.13e-145	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MAKAFAOO_00715	7.07e-53	-	-	-	K	-	-	-	LytTr DNA-binding domain
MAKAFAOO_00717	6.4e-192	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
MAKAFAOO_00718	4.78e-30	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MAKAFAOO_00719	3.59e-60	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MAKAFAOO_00720	9.2e-68	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MAKAFAOO_00721	1.49e-208	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MAKAFAOO_00722	4.78e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
MAKAFAOO_00723	2.53e-130	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MAKAFAOO_00724	7.47e-25	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MAKAFAOO_00725	3.6e-36	ytbE	-	-	S	-	-	-	reductase
MAKAFAOO_00726	4.72e-93	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MAKAFAOO_00728	3.66e-06	vpr	3.4.21.96	-	DO	ko:K01361,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	PA domain
MAKAFAOO_00730	4.43e-72	-	-	-	-	-	-	-	-
MAKAFAOO_00731	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MAKAFAOO_00732	1.28e-202	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAKAFAOO_00733	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAKAFAOO_00734	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MAKAFAOO_00735	1.36e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MAKAFAOO_00736	3.19e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MAKAFAOO_00737	3.86e-81	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MAKAFAOO_00738	4.7e-269	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAKAFAOO_00739	3.64e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MAKAFAOO_00740	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MAKAFAOO_00741	2.93e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MAKAFAOO_00742	3.09e-83	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MAKAFAOO_00743	6.82e-105	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MAKAFAOO_00744	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MAKAFAOO_00745	1.19e-133	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MAKAFAOO_00746	4.03e-103	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MAKAFAOO_00747	1.99e-178	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
MAKAFAOO_00748	3.01e-87	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MAKAFAOO_00749	1.35e-19	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MAKAFAOO_00750	4.83e-204	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MAKAFAOO_00751	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MAKAFAOO_00752	1.52e-126	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MAKAFAOO_00753	1.61e-40	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKAFAOO_00754	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MAKAFAOO_00755	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MAKAFAOO_00756	6.37e-143	-	-	-	P	ko:K12952	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
MAKAFAOO_00757	3.71e-155	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
MAKAFAOO_00758	0.0	ydaO	-	-	E	-	-	-	amino acid
MAKAFAOO_00759	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MAKAFAOO_00760	3.04e-159	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MAKAFAOO_00761	1.13e-68	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MAKAFAOO_00762	7.08e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MAKAFAOO_00763	3.82e-116	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
MAKAFAOO_00764	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MAKAFAOO_00765	1.02e-203	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MAKAFAOO_00766	3.12e-79	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
MAKAFAOO_00767	7.27e-111	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MAKAFAOO_00768	2.62e-104	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAKAFAOO_00769	1.02e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MAKAFAOO_00770	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MAKAFAOO_00771	8.3e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MAKAFAOO_00772	4.11e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MAKAFAOO_00773	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MAKAFAOO_00774	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MAKAFAOO_00775	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MAKAFAOO_00776	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MAKAFAOO_00777	3.24e-101	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
MAKAFAOO_00778	7.15e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MAKAFAOO_00779	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MAKAFAOO_00780	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MAKAFAOO_00781	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MAKAFAOO_00783	1.85e-173	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MAKAFAOO_00784	1.19e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MAKAFAOO_00785	1.99e-264	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MAKAFAOO_00786	4.05e-164	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAKAFAOO_00787	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MAKAFAOO_00788	2.02e-167	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MAKAFAOO_00789	7.94e-134	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
MAKAFAOO_00790	8.04e-212	yclK	-	-	T	-	-	-	Histidine kinase
MAKAFAOO_00791	1.62e-190	-	-	-	E	-	-	-	Major Facilitator Superfamily
MAKAFAOO_00792	2.56e-223	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAKAFAOO_00793	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MAKAFAOO_00794	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MAKAFAOO_00795	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MAKAFAOO_00796	4.5e-52	-	-	-	-	-	-	-	-
MAKAFAOO_00797	4.13e-149	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MAKAFAOO_00798	1.52e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MAKAFAOO_00799	1.16e-179	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MAKAFAOO_00800	7.04e-73	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MAKAFAOO_00801	9.58e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MAKAFAOO_00802	1.49e-146	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MAKAFAOO_00803	2.25e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
MAKAFAOO_00804	3.93e-162	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MAKAFAOO_00805	6.42e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
MAKAFAOO_00806	1.1e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAKAFAOO_00807	1.59e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MAKAFAOO_00808	5.34e-164	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MAKAFAOO_00809	6.04e-24	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
MAKAFAOO_00810	8.54e-251	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MAKAFAOO_00811	1.61e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MAKAFAOO_00812	1.01e-83	-	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MAKAFAOO_00813	2.48e-125	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
MAKAFAOO_00814	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MAKAFAOO_00815	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MAKAFAOO_00816	5.2e-137	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MAKAFAOO_00817	2.99e-185	ymfH	-	-	S	-	-	-	Peptidase M16
MAKAFAOO_00818	9.02e-117	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MAKAFAOO_00819	7.25e-85	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MAKAFAOO_00820	3.46e-110	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MAKAFAOO_00821	3.71e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAKAFAOO_00822	4.38e-256	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MAKAFAOO_00823	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MAKAFAOO_00824	3.27e-286	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MAKAFAOO_00825	1.54e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MAKAFAOO_00826	1.02e-193	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MAKAFAOO_00827	2.76e-229	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MAKAFAOO_00828	1.46e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MAKAFAOO_00829	3.02e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
MAKAFAOO_00831	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
MAKAFAOO_00833	1.68e-263	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
MAKAFAOO_00834	3.54e-150	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
MAKAFAOO_00835	7.03e-311	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
MAKAFAOO_00836	4.44e-85	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
MAKAFAOO_00837	3.91e-184	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MAKAFAOO_00838	3.5e-18	-	-	-	-	-	-	-	-
MAKAFAOO_00839	3.08e-154	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MAKAFAOO_00840	2.13e-236	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MAKAFAOO_00841	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MAKAFAOO_00842	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MAKAFAOO_00843	3.16e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MAKAFAOO_00844	4.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MAKAFAOO_00845	1.6e-14	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MAKAFAOO_00846	3.03e-19	cvpA	-	-	S	-	-	-	Colicin V production protein
MAKAFAOO_00847	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MAKAFAOO_00848	2.59e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MAKAFAOO_00850	7.49e-146	-	-	-	L	-	-	-	four-way junction helicase activity
MAKAFAOO_00855	1.3e-84	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MAKAFAOO_00859	6.79e-51	-	-	-	-	-	-	-	-
MAKAFAOO_00868	1.68e-142	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
MAKAFAOO_00869	7.61e-152	-	-	-	T	-	-	-	diguanylate cyclase activity
MAKAFAOO_00870	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MAKAFAOO_00871	2.01e-254	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MAKAFAOO_00872	9.01e-258	-	-	-	S	-	-	-	Protein conserved in bacteria
MAKAFAOO_00873	1.33e-237	-	-	-	-	-	-	-	-
MAKAFAOO_00874	1.12e-162	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MAKAFAOO_00875	9.51e-49	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
MAKAFAOO_00876	5.25e-183	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
MAKAFAOO_00877	6.22e-197	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MAKAFAOO_00878	2.45e-134	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MAKAFAOO_00879	1.31e-120	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MAKAFAOO_00880	9.93e-276	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
MAKAFAOO_00881	3.12e-253	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MAKAFAOO_00882	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MAKAFAOO_00883	1.06e-243	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MAKAFAOO_00884	9.44e-203	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MAKAFAOO_00885	1e-49	-	-	-	M	-	-	-	LysM domain
MAKAFAOO_00886	1.02e-272	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MAKAFAOO_00887	3.29e-61	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MAKAFAOO_00888	6.58e-86	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MAKAFAOO_00889	2.89e-287	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MAKAFAOO_00890	1.3e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
MAKAFAOO_00891	1.44e-123	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MAKAFAOO_00892	5.19e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MAKAFAOO_00893	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MAKAFAOO_00894	7.48e-147	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MAKAFAOO_00895	6.43e-149	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MAKAFAOO_00896	2.26e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MAKAFAOO_00897	1.21e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MAKAFAOO_00898	1.39e-100	-	-	-	S	-	-	-	VIT family
MAKAFAOO_00899	2.71e-107	-	-	-	S	-	-	-	membrane
MAKAFAOO_00900	1.97e-53	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MAKAFAOO_00901	5.92e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MAKAFAOO_00902	2.89e-47	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MAKAFAOO_00903	8.46e-97	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAKAFAOO_00905	2.23e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MAKAFAOO_00907	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MAKAFAOO_00908	1.26e-202	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MAKAFAOO_00909	4.81e-54	-	-	-	S	-	-	-	VanZ like family
MAKAFAOO_00910	4e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MAKAFAOO_00911	9.45e-129	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAKAFAOO_00912	3.19e-152	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MAKAFAOO_00913	1.95e-122	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MAKAFAOO_00914	3.06e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MAKAFAOO_00915	5.05e-18	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MAKAFAOO_00919	7e-124	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MAKAFAOO_00920	1.27e-238	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MAKAFAOO_00921	9.2e-73	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MAKAFAOO_00922	3.03e-77	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MAKAFAOO_00923	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MAKAFAOO_00924	6.54e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MAKAFAOO_00925	3.79e-118	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MAKAFAOO_00926	2.32e-118	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MAKAFAOO_00927	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
MAKAFAOO_00928	1.05e-96	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAKAFAOO_00929	1.41e-57	ytpP	-	-	CO	-	-	-	Thioredoxin
MAKAFAOO_00930	4.74e-130	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MAKAFAOO_00931	2.39e-125	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
MAKAFAOO_00932	5.63e-88	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MAKAFAOO_00933	8.15e-122	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_00934	7.73e-69	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
MAKAFAOO_00936	7.01e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MAKAFAOO_00937	2.18e-161	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAKAFAOO_00938	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MAKAFAOO_00939	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MAKAFAOO_00941	3.24e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MAKAFAOO_00942	9.52e-223	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MAKAFAOO_00943	3.44e-92	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MAKAFAOO_00944	2.26e-59	ykuL	-	-	S	-	-	-	CBS domain
MAKAFAOO_00945	1.05e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
MAKAFAOO_00946	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MAKAFAOO_00947	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MAKAFAOO_00948	1.89e-291	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MAKAFAOO_00949	7.35e-140	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MAKAFAOO_00950	4.27e-130	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MAKAFAOO_00951	9e-158	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MAKAFAOO_00952	5.08e-275	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MAKAFAOO_00953	2.67e-83	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MAKAFAOO_00954	9.49e-60	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MAKAFAOO_00955	4.97e-248	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MAKAFAOO_00956	2.21e-125	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MAKAFAOO_00957	9.85e-130	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MAKAFAOO_00958	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAKAFAOO_00959	3.47e-128	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAKAFAOO_00960	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MAKAFAOO_00961	7.61e-86	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MAKAFAOO_00962	2.43e-48	-	-	-	-	-	-	-	-
MAKAFAOO_00964	4.99e-136	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKAFAOO_00966	1.88e-86	-	-	-	D	-	-	-	nuclear chromosome segregation
MAKAFAOO_00967	1.05e-08	-	-	-	K	-	-	-	sequence-specific DNA binding
MAKAFAOO_00968	2.63e-248	-	-	-	V	-	-	-	Type I restriction-modification system methyltransferase subunit
MAKAFAOO_00969	3.69e-100	-	-	-	S	-	-	-	Fic/DOC family
MAKAFAOO_00970	3.94e-39	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MAKAFAOO_00971	9.99e-18	-	-	-	T	-	-	-	PFAM SpoVT AbrB
MAKAFAOO_00972	2.24e-35	-	-	-	-	-	-	-	-
MAKAFAOO_00973	9.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
MAKAFAOO_00974	4.43e-38	-	-	-	L	-	-	-	four-way junction helicase activity
MAKAFAOO_00978	2.11e-67	repB	-	-	L	-	-	-	Initiator Replication protein
MAKAFAOO_00980	4.31e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MAKAFAOO_00981	4.52e-05	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
MAKAFAOO_00992	4.44e-14	-	-	-	S	-	-	-	Arc-like DNA binding domain
MAKAFAOO_00993	8.96e-10	-	-	-	-	-	-	-	-
MAKAFAOO_00994	7.27e-17	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAKAFAOO_00995	5.32e-18	-	-	-	-	-	-	-	-
MAKAFAOO_00996	1.07e-141	rssA	-	-	S	-	-	-	Phospholipase, patatin family
MAKAFAOO_01003	1.26e-18	-	-	-	-	-	-	-	-
MAKAFAOO_01004	3.79e-39	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAKAFAOO_01006	4.38e-165	-	-	-	NU	-	-	-	StbA protein
MAKAFAOO_01008	2.72e-09	-	-	-	-	-	-	-	-
MAKAFAOO_01009	2.85e-35	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAKAFAOO_01019	3.26e-31	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MAKAFAOO_01020	7.76e-58	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MAKAFAOO_01027	1.5e-12	-	-	-	S	-	-	-	AAA ATPase domain
MAKAFAOO_01033	1.54e-55	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MAKAFAOO_01034	7.25e-103	-	-	-	M	-	-	-	Gram-positive pilin backbone subunit 2, Cna-B-like domain
MAKAFAOO_01044	3.53e-158	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAKAFAOO_01045	1.34e-218	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MAKAFAOO_01046	2.26e-148	ydbI	-	-	K	-	-	-	AI-2E family transporter
MAKAFAOO_01047	4.18e-76	-	-	-	EG	-	-	-	EamA-like transporter family
MAKAFAOO_01048	6.46e-98	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
MAKAFAOO_01049	4.86e-148	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MAKAFAOO_01050	3.14e-86	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MAKAFAOO_01051	2.21e-208	-	-	-	C	-	-	-	Luciferase-like monooxygenase
MAKAFAOO_01052	1.7e-55	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MAKAFAOO_01053	6.68e-219	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MAKAFAOO_01054	2.09e-132	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MAKAFAOO_01055	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MAKAFAOO_01056	1.46e-107	pncA	-	-	Q	-	-	-	isochorismatase
MAKAFAOO_01057	2.29e-81	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
MAKAFAOO_01058	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MAKAFAOO_01059	2.39e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
MAKAFAOO_01060	6.01e-316	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MAKAFAOO_01061	1.18e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MAKAFAOO_01063	5.81e-67	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MAKAFAOO_01064	6.58e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MAKAFAOO_01065	1.46e-213	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MAKAFAOO_01066	3.47e-160	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MAKAFAOO_01067	5.15e-224	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MAKAFAOO_01068	3.5e-214	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MAKAFAOO_01069	5.42e-272	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKAFAOO_01071	1.01e-77	-	-	-	T	-	-	-	Universal stress protein family
MAKAFAOO_01072	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
MAKAFAOO_01073	3.77e-35	-	-	-	-	-	-	-	-
MAKAFAOO_01074	3.76e-252	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MAKAFAOO_01075	4.31e-141	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MAKAFAOO_01076	7.22e-107	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MAKAFAOO_01077	1e-65	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MAKAFAOO_01078	2.03e-73	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MAKAFAOO_01079	2.44e-188	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MAKAFAOO_01080	6.78e-80	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MAKAFAOO_01081	8.04e-19	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MAKAFAOO_01082	3.14e-35	cpsJ	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
MAKAFAOO_01083	5.25e-43	-	-	-	M	-	-	-	family 8
MAKAFAOO_01084	4.59e-40	-	-	-	S	-	-	-	glycosyl transferase family 2
MAKAFAOO_01085	3.32e-89	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
MAKAFAOO_01086	4.24e-46	-	-	-	S	-	-	-	glycosyl transferase family 2
MAKAFAOO_01087	9.48e-41	cpsJ	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
MAKAFAOO_01088	3.76e-98	arbY	-	-	M	-	-	-	family 8
MAKAFAOO_01089	7.14e-138	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MAKAFAOO_01090	1.46e-19	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MAKAFAOO_01091	1.44e-48	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MAKAFAOO_01092	2.91e-190	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MAKAFAOO_01093	3.17e-174	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MAKAFAOO_01094	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
MAKAFAOO_01095	3.32e-64	-	-	-	S	-	-	-	VIT family
MAKAFAOO_01096	3.74e-303	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MAKAFAOO_01097	1.15e-53	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MAKAFAOO_01098	1.34e-182	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MAKAFAOO_01099	7.46e-180	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MAKAFAOO_01100	1.5e-147	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MAKAFAOO_01101	4.47e-281	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MAKAFAOO_01102	1.76e-35	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAKAFAOO_01104	6e-42	-	-	-	S	-	-	-	ABC-2 family transporter protein
MAKAFAOO_01105	3.04e-92	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MAKAFAOO_01106	8.32e-130	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MAKAFAOO_01107	9.3e-113	spaR	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MAKAFAOO_01108	1.1e-172	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MAKAFAOO_01109	2.37e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MAKAFAOO_01110	1.16e-82	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
MAKAFAOO_01111	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MAKAFAOO_01112	1.48e-173	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
MAKAFAOO_01113	1.93e-106	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
MAKAFAOO_01114	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
MAKAFAOO_01115	5.47e-93	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MAKAFAOO_01116	1.37e-140	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
MAKAFAOO_01117	1.22e-26	-	-	-	M	-	-	-	by MetaGeneAnnotator
MAKAFAOO_01120	4.81e-19	-	-	-	-	-	-	-	-
MAKAFAOO_01121	4.91e-112	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MAKAFAOO_01122	1.29e-200	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MAKAFAOO_01123	1.06e-76	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MAKAFAOO_01132	5.71e-71	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MAKAFAOO_01133	2.56e-65	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MAKAFAOO_01141	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAKAFAOO_01142	7.78e-101	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
MAKAFAOO_01143	3.85e-45	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MAKAFAOO_01144	2.18e-47	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MAKAFAOO_01148	2.51e-88	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MAKAFAOO_01149	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
MAKAFAOO_01150	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MAKAFAOO_01151	2.04e-123	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
MAKAFAOO_01155	1.36e-08	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MAKAFAOO_01156	6.2e-13	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
MAKAFAOO_01157	1.62e-13	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
MAKAFAOO_01160	3.46e-100	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
MAKAFAOO_01161	7.64e-70	-	-	-	S	-	-	-	UPF0489 domain
MAKAFAOO_01164	1.93e-42	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MAKAFAOO_01165	1.48e-30	-	-	-	-	-	-	-	-
MAKAFAOO_01166	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
MAKAFAOO_01167	1.99e-60	-	-	-	L	-	-	-	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
MAKAFAOO_01168	2.31e-68	-	-	-	L	-	-	-	Resolvase, N terminal domain
MAKAFAOO_01169	2.68e-264	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAKAFAOO_01170	5.09e-183	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MAKAFAOO_01171	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAKAFAOO_01172	5.93e-294	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MAKAFAOO_01173	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAKAFAOO_01174	6.9e-205	camS	-	-	S	-	-	-	sex pheromone
MAKAFAOO_01175	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MAKAFAOO_01176	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MAKAFAOO_01177	2.85e-183	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MAKAFAOO_01180	6.69e-94	-	-	-	DM	-	-	-	Glucan-binding protein C
MAKAFAOO_01181	8.77e-10	-	-	-	-	-	-	-	-
MAKAFAOO_01183	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MAKAFAOO_01184	1.83e-80	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MAKAFAOO_01186	4.53e-72	-	-	-	-	-	-	-	-
MAKAFAOO_01187	3.15e-25	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
MAKAFAOO_01188	3.04e-200	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
MAKAFAOO_01191	8.69e-182	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MAKAFAOO_01195	1.09e-264	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MAKAFAOO_01196	2.72e-85	-	-	-	-	-	-	-	-
MAKAFAOO_01199	6.85e-237	-	-	-	U	-	-	-	type IV secretory pathway VirB4
MAKAFAOO_01201	2.61e-34	-	-	-	M	-	-	-	CHAP domain
MAKAFAOO_01205	2.11e-72	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKAFAOO_01206	2.04e-33	-	-	-	-	-	-	-	-
MAKAFAOO_01207	3.52e-100	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MAKAFAOO_01208	6.66e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MAKAFAOO_01209	6.63e-06	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MAKAFAOO_01210	2.78e-99	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MAKAFAOO_01211	2.75e-67	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MAKAFAOO_01212	4.33e-73	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAKAFAOO_01213	1.75e-99	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
MAKAFAOO_01214	1.85e-89	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MAKAFAOO_01215	4.89e-129	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MAKAFAOO_01218	1.49e-19	-	-	-	S	-	-	-	YjcQ protein
MAKAFAOO_01220	1.54e-43	-	-	-	-	-	-	-	-
MAKAFAOO_01221	4.29e-16	-	-	-	-	-	-	-	-
MAKAFAOO_01222	4.43e-181	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
MAKAFAOO_01223	4.15e-90	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MAKAFAOO_01224	8.49e-175	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MAKAFAOO_01225	4.18e-271	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAKAFAOO_01226	1.73e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MAKAFAOO_01227	3.01e-176	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MAKAFAOO_01228	6.52e-90	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
MAKAFAOO_01229	1.75e-123	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MAKAFAOO_01230	7.6e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MAKAFAOO_01231	6.15e-48	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MAKAFAOO_01232	6.25e-233	-	-	-	L	-	-	-	Probable transposase
MAKAFAOO_01233	1.57e-40	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MAKAFAOO_01234	5.67e-27	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
MAKAFAOO_01235	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
MAKAFAOO_01236	4.01e-44	-	-	-	P	-	-	-	Heavy-metal-associated domain
MAKAFAOO_01237	1.75e-161	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
MAKAFAOO_01238	7.24e-121	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
MAKAFAOO_01239	1e-13	-	-	-	L	ko:K07498	-	ko00000	Lactococcus lactis RepB C-terminus
MAKAFAOO_01240	3.03e-67	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
MAKAFAOO_01241	3.22e-140	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MAKAFAOO_01242	1.23e-34	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
MAKAFAOO_01243	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MAKAFAOO_01244	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAKAFAOO_01245	4.33e-48	-	-	-	S	-	-	-	Enterocin A Immunity
MAKAFAOO_01246	2.07e-103	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
MAKAFAOO_01247	2.18e-73	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MAKAFAOO_01248	3.17e-147	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MAKAFAOO_01249	4.71e-187	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MAKAFAOO_01250	1.11e-214	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
MAKAFAOO_01253	4.29e-115	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
MAKAFAOO_01254	1.95e-122	-	-	-	L	-	-	-	Type II restriction endonuclease, TdeIII
MAKAFAOO_01255	6.24e-26	-	-	-	K	-	-	-	Transcriptional
MAKAFAOO_01256	1.23e-121	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
MAKAFAOO_01258	3.38e-296	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
MAKAFAOO_01259	5.5e-118	-	-	-	S	-	-	-	SIR2-like domain
MAKAFAOO_01260	0.000777	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
MAKAFAOO_01261	7.22e-85	-	-	-	-	-	-	-	-
MAKAFAOO_01262	2.85e-76	-	-	-	-	-	-	-	-
MAKAFAOO_01263	8.97e-207	-	-	-	L	-	-	-	T/G mismatch-specific endonuclease activity
MAKAFAOO_01265	5.66e-70	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MAKAFAOO_01267	4.4e-19	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MAKAFAOO_01268	2.82e-85	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MAKAFAOO_01271	6.16e-68	-	-	-	S	-	-	-	EVIDENCE BY HOMOLOGY BIO14.03 Phage related functions and prophages
MAKAFAOO_01272	6.84e-86	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MAKAFAOO_01274	1.78e-158	yvgN	-	-	C	-	-	-	Aldo keto reductase
MAKAFAOO_01277	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MAKAFAOO_01278	6.84e-38	-	-	-	-	-	-	-	-
MAKAFAOO_01280	3.22e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
MAKAFAOO_01281	4.55e-14	-	-	-	D	-	-	-	LPXTG cell wall anchor motif
MAKAFAOO_01282	3.06e-07	-	-	-	-	-	-	-	-
MAKAFAOO_01283	0.00071	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MAKAFAOO_01284	5.62e-12	polC_2	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	3' exoribonuclease, RNase T-like
MAKAFAOO_01285	9.46e-133	-	-	-	-	-	-	-	-
MAKAFAOO_01286	1e-282	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG3505 Type IV secretory pathway, VirD4 components
MAKAFAOO_01289	6.71e-241	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MAKAFAOO_01293	1.16e-242	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	C-terminal repeat of topoisomerase
MAKAFAOO_01295	3.79e-55	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
MAKAFAOO_01296	2.36e-46	-	-	-	-	-	-	-	-
MAKAFAOO_01297	1.84e-21	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MAKAFAOO_01298	8e-86	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MAKAFAOO_01299	1.78e-112	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MAKAFAOO_01300	1.92e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MAKAFAOO_01301	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MAKAFAOO_01302	3.11e-33	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MAKAFAOO_01303	8.79e-140	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MAKAFAOO_01304	4.97e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MAKAFAOO_01305	2.16e-104	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MAKAFAOO_01306	3.62e-130	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MAKAFAOO_01307	1.17e-161	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MAKAFAOO_01308	1.97e-91	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MAKAFAOO_01309	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MAKAFAOO_01310	1.94e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
MAKAFAOO_01311	1.73e-93	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MAKAFAOO_01313	2.93e-82	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MAKAFAOO_01314	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MAKAFAOO_01315	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MAKAFAOO_01316	5e-45	-	-	-	-	-	-	-	-
MAKAFAOO_01317	2.47e-141	-	-	-	M	-	-	-	lysozyme activity
MAKAFAOO_01318	1.63e-26	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MAKAFAOO_01320	5.15e-18	-	-	-	-	-	-	-	-
MAKAFAOO_01322	8.18e-60	-	-	-	M	-	-	-	Prophage endopeptidase tail
MAKAFAOO_01323	7.3e-21	-	-	-	S	-	-	-	phage tail
MAKAFAOO_01324	7.7e-187	-	-	-	S	-	-	-	peptidoglycan catabolic process
MAKAFAOO_01328	1.46e-39	-	-	-	-	-	-	-	-
MAKAFAOO_01329	2.49e-30	-	-	-	-	-	-	-	-
MAKAFAOO_01330	2.21e-12	-	-	-	-	-	-	-	-
MAKAFAOO_01331	1.58e-126	-	-	-	S	-	-	-	Phage capsid family
MAKAFAOO_01332	1.09e-67	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
MAKAFAOO_01333	1.37e-101	-	-	-	S	-	-	-	Phage portal protein
MAKAFAOO_01334	1.91e-225	-	-	-	S	-	-	-	Terminase
MAKAFAOO_01336	1.04e-34	-	-	-	V	-	-	-	HNH nucleases
MAKAFAOO_01337	1.38e-27	-	-	-	-	-	-	-	-
MAKAFAOO_01338	2.55e-49	-	-	-	S	-	-	-	Type I restriction modification DNA specificity domain
MAKAFAOO_01339	1.97e-171	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MAKAFAOO_01346	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MAKAFAOO_01347	3.15e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MAKAFAOO_01348	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MAKAFAOO_01349	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MAKAFAOO_01350	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MAKAFAOO_01351	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MAKAFAOO_01352	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MAKAFAOO_01353	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
MAKAFAOO_01354	2.29e-139	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAKAFAOO_01355	1.71e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MAKAFAOO_01356	5.29e-262	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MAKAFAOO_01357	7.38e-313	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAKAFAOO_01358	2.78e-195	yacL	-	-	S	-	-	-	domain protein
MAKAFAOO_01359	4.62e-283	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MAKAFAOO_01360	6.53e-93	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MAKAFAOO_01361	1.17e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
MAKAFAOO_01362	7.36e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MAKAFAOO_01363	2.77e-45	-	-	-	S	-	-	-	Enterocin A Immunity
MAKAFAOO_01364	4.1e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAKAFAOO_01365	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
MAKAFAOO_01366	1.08e-147	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAKAFAOO_01368	3.08e-52	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MAKAFAOO_01369	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
MAKAFAOO_01370	5.34e-165	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MAKAFAOO_01371	8.88e-307	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MAKAFAOO_01372	1.65e-113	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MAKAFAOO_01373	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
MAKAFAOO_01374	4.28e-115	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MAKAFAOO_01378	7.34e-131	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MAKAFAOO_01379	6.35e-77	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
MAKAFAOO_01380	2.54e-202	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MAKAFAOO_01381	2.02e-41	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MAKAFAOO_01382	3.63e-267	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MAKAFAOO_01383	1.6e-248	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAKAFAOO_01384	4.35e-301	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MAKAFAOO_01385	2.77e-19	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
MAKAFAOO_01386	1.83e-224	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MAKAFAOO_01387	3.47e-75	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MAKAFAOO_01388	3.66e-123	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MAKAFAOO_01389	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MAKAFAOO_01390	1.25e-92	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MAKAFAOO_01391	1.04e-82	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MAKAFAOO_01393	3.03e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MAKAFAOO_01394	1.26e-268	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MAKAFAOO_01395	5.87e-129	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MAKAFAOO_01396	1.01e-177	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MAKAFAOO_01398	1.68e-22	-	-	-	-	-	-	-	-
MAKAFAOO_01399	2.54e-255	oatA	-	-	I	-	-	-	Acyltransferase
MAKAFAOO_01400	1.65e-272	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MAKAFAOO_01401	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MAKAFAOO_01402	4.03e-177	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKAFAOO_01405	1.04e-52	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MAKAFAOO_01406	5.13e-93	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MAKAFAOO_01407	5.86e-78	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MAKAFAOO_01408	1.02e-11	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
MAKAFAOO_01410	5.1e-75	-	-	-	K	-	-	-	WYL domain
MAKAFAOO_01411	2.43e-09	-	-	-	S	-	-	-	Mor transcription activator family
MAKAFAOO_01417	1.02e-159	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
MAKAFAOO_01418	6.22e-164	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MAKAFAOO_01419	1.81e-24	-	-	-	-	-	-	-	-
MAKAFAOO_01420	3.08e-133	-	-	-	E	-	-	-	AzlC protein
MAKAFAOO_01421	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
MAKAFAOO_01422	2.12e-82	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MAKAFAOO_01423	2.16e-23	-	-	-	-	-	-	-	-
MAKAFAOO_01424	2.26e-75	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
MAKAFAOO_01425	3.33e-27	-	-	-	-	-	-	-	-
MAKAFAOO_01426	1.01e-117	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAKAFAOO_01427	1.77e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
MAKAFAOO_01428	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MAKAFAOO_01429	5.21e-226	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAKAFAOO_01430	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MAKAFAOO_01431	3.26e-245	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MAKAFAOO_01432	1.99e-243	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MAKAFAOO_01433	7.85e-79	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MAKAFAOO_01434	5.46e-105	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MAKAFAOO_01435	1.08e-242	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MAKAFAOO_01436	1.12e-224	-	-	-	S	-	-	-	Protein of unknown function DUF262
MAKAFAOO_01437	9.81e-25	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MAKAFAOO_01438	3.92e-60	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MAKAFAOO_01442	5.97e-95	-	-	-	L	-	-	-	Lactococcus lactis RepB C-terminus
MAKAFAOO_01443	2.27e-80	-	-	-	EP	-	-	-	Plasmid replication protein
MAKAFAOO_01445	2.93e-174	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MAKAFAOO_01449	3.72e-21	-	-	-	D	-	-	-	nuclear chromosome segregation
MAKAFAOO_01450	5.17e-253	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MAKAFAOO_01451	1.6e-155	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MAKAFAOO_01453	4.34e-96	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MAKAFAOO_01454	2.11e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MAKAFAOO_01455	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MAKAFAOO_01456	0.0	-	-	-	S	-	-	-	membrane
MAKAFAOO_01458	2.73e-25	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
MAKAFAOO_01459	4.25e-20	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
MAKAFAOO_01463	5.35e-89	-	-	-	-	-	-	-	-
MAKAFAOO_01464	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
MAKAFAOO_01466	4.02e-70	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
MAKAFAOO_01469	2.01e-161	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MAKAFAOO_01470	1.09e-37	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
MAKAFAOO_01471	3.42e-65	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MAKAFAOO_01472	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAKAFAOO_01473	8.05e-143	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MAKAFAOO_01474	1.92e-239	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MAKAFAOO_01475	9.01e-68	-	-	-	S	-	-	-	Membrane
MAKAFAOO_01476	3.12e-77	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MAKAFAOO_01478	1.59e-266	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKAFAOO_01479	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MAKAFAOO_01480	2.68e-238	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MAKAFAOO_01481	7.86e-78	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MAKAFAOO_01482	3.53e-144	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MAKAFAOO_01483	1.12e-105	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MAKAFAOO_01484	4.12e-82	-	-	-	-	-	-	-	-
MAKAFAOO_01485	3.58e-227	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MAKAFAOO_01486	1.53e-55	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MAKAFAOO_01488	2.79e-105	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
MAKAFAOO_01489	1.26e-53	ywnA	-	-	K	-	-	-	Transcriptional regulator
MAKAFAOO_01490	1.98e-42	-	-	-	S	-	-	-	CHY zinc finger
MAKAFAOO_01491	1.11e-29	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
MAKAFAOO_01492	3.51e-67	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MAKAFAOO_01493	0.0	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
MAKAFAOO_01494	1.29e-175	-	-	-	L	-	-	-	helicase
MAKAFAOO_01496	2.29e-51	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MAKAFAOO_01497	4.47e-29	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
MAKAFAOO_01499	3.19e-51	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
MAKAFAOO_01500	4.12e-91	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
MAKAFAOO_01501	1.85e-83	-	-	-	H	-	-	-	Methyltransferase domain
MAKAFAOO_01508	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MAKAFAOO_01509	1.55e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
MAKAFAOO_01510	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MAKAFAOO_01511	1.21e-20	-	-	-	-	-	-	-	-
MAKAFAOO_01514	6.37e-88	-	-	-	-	-	-	-	-
MAKAFAOO_01515	1.18e-125	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MAKAFAOO_01516	4.46e-225	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MAKAFAOO_01517	5.15e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
MAKAFAOO_01518	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MAKAFAOO_01519	6.04e-275	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MAKAFAOO_01520	6.85e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MAKAFAOO_01521	9.74e-76	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MAKAFAOO_01522	3.13e-78	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MAKAFAOO_01523	5.4e-126	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MAKAFAOO_01524	6.23e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MAKAFAOO_01525	1.16e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
MAKAFAOO_01526	4.35e-159	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MAKAFAOO_01527	1.7e-143	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MAKAFAOO_01528	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MAKAFAOO_01529	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MAKAFAOO_01530	2.16e-236	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MAKAFAOO_01531	3.94e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MAKAFAOO_01532	9.75e-245	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
MAKAFAOO_01534	1.38e-92	-	-	-	M	-	-	-	GNAT acetyltransferase
MAKAFAOO_01535	1.34e-86	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MAKAFAOO_01536	5.43e-73	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MAKAFAOO_01537	1.51e-103	-	-	-	F	-	-	-	Hydrolase, nudix family
MAKAFAOO_01539	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MAKAFAOO_01540	2.09e-267	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MAKAFAOO_01541	3.84e-114	-	-	-	V	-	-	-	Type I restriction
MAKAFAOO_01542	1.9e-166	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKAFAOO_01543	1.05e-87	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I Restriction
MAKAFAOO_01544	6.9e-70	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
MAKAFAOO_01545	2.12e-87	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAKAFAOO_01546	1.33e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MAKAFAOO_01547	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MAKAFAOO_01548	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MAKAFAOO_01549	1.03e-262	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MAKAFAOO_01550	5.37e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MAKAFAOO_01551	3.6e-276	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MAKAFAOO_01552	5.3e-80	-	-	-	S	-	-	-	Helix-turn-helix domain
MAKAFAOO_01553	1.62e-156	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MAKAFAOO_01554	3.56e-27	-	-	-	M	-	-	-	Lysin motif
MAKAFAOO_01555	2.06e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MAKAFAOO_01556	4.22e-106	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
MAKAFAOO_01557	5.08e-197	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MAKAFAOO_01558	6.93e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MAKAFAOO_01559	1.69e-39	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MAKAFAOO_01560	4.63e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAKAFAOO_01561	1.65e-115	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MAKAFAOO_01563	2.4e-273	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAKAFAOO_01564	5.54e-222	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MAKAFAOO_01565	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAKAFAOO_01566	5.77e-192	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MAKAFAOO_01567	2.35e-76	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
MAKAFAOO_01568	3.19e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MAKAFAOO_01569	1.17e-288	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MAKAFAOO_01570	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAKAFAOO_01572	2.01e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MAKAFAOO_01573	1.99e-141	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
MAKAFAOO_01574	1.51e-103	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
MAKAFAOO_01575	2.08e-121	-	-	-	EG	-	-	-	EamA-like transporter family
MAKAFAOO_01576	1.64e-97	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MAKAFAOO_01577	2.62e-236	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MAKAFAOO_01578	3.86e-53	-	-	-	S	-	-	-	ASCH
MAKAFAOO_01579	3.34e-127	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKAFAOO_01580	1.01e-08	-	-	-	-	-	-	-	-
MAKAFAOO_01581	4.82e-49	-	-	-	K	-	-	-	Peptidase S24-like
MAKAFAOO_01582	2.91e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAKAFAOO_01583	2.28e-42	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
MAKAFAOO_01584	5.73e-34	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
MAKAFAOO_01585	3.53e-05	-	-	-	S	-	-	-	EVIDENCE BY HOMOLOGY BIO14.03 Phage related functions and prophages
MAKAFAOO_01590	2.63e-67	-	-	-	S	-	-	-	Putative HNHc nuclease
MAKAFAOO_01591	2.41e-27	-	-	-	S	-	-	-	Phage replisome organizer, N-terminal domain protein
MAKAFAOO_01594	4.18e-28	-	-	-	-	-	-	-	-
MAKAFAOO_01595	1.63e-88	-	-	-	-	-	-	-	-
MAKAFAOO_01602	3.46e-78	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
MAKAFAOO_01603	1.22e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MAKAFAOO_01605	2.37e-290	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MAKAFAOO_01606	3.42e-82	-	-	-	C	-	-	-	FMN binding
MAKAFAOO_01607	1.24e-260	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MAKAFAOO_01608	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MAKAFAOO_01609	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MAKAFAOO_01612	1.03e-123	-	-	-	S	-	-	-	MobA/MobL family
MAKAFAOO_01614	3.99e-89	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
MAKAFAOO_01615	2.3e-42	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
MAKAFAOO_01617	2.19e-70	repB	-	-	L	-	-	-	Initiator Replication protein
MAKAFAOO_01620	1.8e-203	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MAKAFAOO_01621	1.03e-249	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MAKAFAOO_01622	2.37e-70	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MAKAFAOO_01623	6.41e-167	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
MAKAFAOO_01624	5.93e-128	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MAKAFAOO_01625	1.04e-102	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MAKAFAOO_01626	3.84e-05	-	-	-	S	-	-	-	Phage minor structural protein GP20
MAKAFAOO_01627	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MAKAFAOO_01629	2.02e-256	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKAFAOO_01630	7.44e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_01631	3.69e-41	-	-	-	-	-	-	-	-
MAKAFAOO_01632	1.77e-139	ampC	-	-	V	-	-	-	Beta-lactamase
MAKAFAOO_01635	7.62e-80	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
MAKAFAOO_01636	5.81e-98	-	-	-	S	-	-	-	N-methyltransferase activity
MAKAFAOO_01637	5.81e-246	-	-	-	S	-	-	-	Domain of unknown function (DUF3440)
MAKAFAOO_01638	1.14e-156	-	-	-	S	-	-	-	Type III restriction enzyme, res subunit
MAKAFAOO_01642	1.9e-235	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKAFAOO_01643	2.17e-101	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MAKAFAOO_01644	2.76e-87	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
MAKAFAOO_01645	2.02e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MAKAFAOO_01646	1.05e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MAKAFAOO_01647	6.36e-95	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MAKAFAOO_01648	8.13e-42	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
MAKAFAOO_01651	4e-99	-	-	-	L	-	-	-	Replication protein
MAKAFAOO_01652	4.35e-10	-	-	-	-	-	-	-	-
MAKAFAOO_01654	9.79e-58	-	-	-	L	-	-	-	DnaD domain protein
MAKAFAOO_01662	2.94e-56	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
MAKAFAOO_01665	1.96e-296	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MAKAFAOO_01666	2.49e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MAKAFAOO_01667	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MAKAFAOO_01668	1.7e-87	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MAKAFAOO_01669	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MAKAFAOO_01670	3.45e-136	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MAKAFAOO_01671	2.15e-62	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MAKAFAOO_01672	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MAKAFAOO_01673	3.48e-95	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
MAKAFAOO_01674	6.97e-138	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MAKAFAOO_01675	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MAKAFAOO_01676	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MAKAFAOO_01677	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MAKAFAOO_01678	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MAKAFAOO_01679	7.82e-90	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MAKAFAOO_01680	2.94e-229	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MAKAFAOO_01681	4.74e-41	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
MAKAFAOO_01682	4.98e-99	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MAKAFAOO_01683	1.14e-89	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MAKAFAOO_01684	1.13e-64	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MAKAFAOO_01685	1.86e-103	-	-	-	H	-	-	-	Nodulation protein S (NodS)
MAKAFAOO_01686	3.99e-154	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MAKAFAOO_01687	4.52e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MAKAFAOO_01688	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MAKAFAOO_01689	9.97e-114	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MAKAFAOO_01690	4.86e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MAKAFAOO_01691	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
MAKAFAOO_01692	4.91e-172	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MAKAFAOO_01693	7.31e-164	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MAKAFAOO_01694	1.82e-49	-	-	-	-	-	-	-	-
MAKAFAOO_01695	4.68e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MAKAFAOO_01696	6.6e-76	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MAKAFAOO_01697	1.28e-199	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MAKAFAOO_01698	3.59e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MAKAFAOO_01699	1.73e-139	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MAKAFAOO_01701	1.46e-141	csrR	-	-	K	-	-	-	response regulator
MAKAFAOO_01702	1.03e-216	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAKAFAOO_01703	2.4e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAKAFAOO_01704	1.6e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MAKAFAOO_01705	1.57e-168	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MAKAFAOO_01706	1.74e-142	-	-	-	-	-	-	-	-
MAKAFAOO_01707	1.14e-147	-	-	-	-	-	-	-	-
MAKAFAOO_01708	1.45e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
MAKAFAOO_01709	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAKAFAOO_01710	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MAKAFAOO_01711	1.02e-46	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MAKAFAOO_01712	3.32e-133	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAKAFAOO_01713	9.35e-181	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAKAFAOO_01714	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAKAFAOO_01715	5.41e-105	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MAKAFAOO_01716	6.31e-154	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MAKAFAOO_01717	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MAKAFAOO_01718	1.05e-235	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MAKAFAOO_01719	6.38e-107	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MAKAFAOO_01720	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
MAKAFAOO_01721	3.28e-35	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MAKAFAOO_01722	1.61e-118	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MAKAFAOO_01723	1.78e-57	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
MAKAFAOO_01724	2.1e-86	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
MAKAFAOO_01726	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MAKAFAOO_01727	2.55e-49	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MAKAFAOO_01728	1.83e-89	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
MAKAFAOO_01729	1.74e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MAKAFAOO_01730	1.59e-200	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MAKAFAOO_01731	2.92e-60	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MAKAFAOO_01732	6.17e-24	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
MAKAFAOO_01733	4.29e-141	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MAKAFAOO_01734	3.84e-258	ynbB	-	-	P	-	-	-	aluminum resistance
MAKAFAOO_01735	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
MAKAFAOO_01736	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MAKAFAOO_01738	4.32e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MAKAFAOO_01739	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
MAKAFAOO_01740	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MAKAFAOO_01741	2.03e-105	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MAKAFAOO_01742	1.42e-134	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MAKAFAOO_01743	7.84e-132	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MAKAFAOO_01744	7.2e-196	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MAKAFAOO_01745	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MAKAFAOO_01746	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAKAFAOO_01747	6.68e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MAKAFAOO_01748	8.77e-217	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MAKAFAOO_01749	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MAKAFAOO_01750	3.59e-34	ylxQ	-	-	J	-	-	-	ribosomal protein
MAKAFAOO_01751	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MAKAFAOO_01752	6.33e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MAKAFAOO_01753	2.02e-152	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAKAFAOO_01754	1.39e-119	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MAKAFAOO_01755	6.14e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MAKAFAOO_01756	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MAKAFAOO_01757	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MAKAFAOO_01758	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MAKAFAOO_01759	6.27e-15	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MAKAFAOO_01761	3.81e-22	-	-	-	S	-	-	-	Phage minor capsid protein 2
MAKAFAOO_01762	5.96e-35	-	-	-	S	-	-	-	Phage minor capsid protein 2
MAKAFAOO_01767	2.67e-95	-	-	-	S	-	-	-	Cell surface protein
MAKAFAOO_01770	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MAKAFAOO_01771	1.13e-57	-	-	-	S	-	-	-	Plasmid replication protein
MAKAFAOO_01772	1.08e-118	tnp2	-	-	L	-	-	-	Transposase
MAKAFAOO_01784	8.93e-133	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MAKAFAOO_01785	1.31e-125	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MAKAFAOO_01786	3.47e-138	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MAKAFAOO_01787	3.99e-71	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MAKAFAOO_01788	6.68e-128	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MAKAFAOO_01789	3.33e-113	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MAKAFAOO_01790	4.09e-35	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MAKAFAOO_01791	5.73e-90	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAKAFAOO_01793	6.13e-192	-	-	-	EGP	-	-	-	Major Facilitator
MAKAFAOO_01794	2.95e-81	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MAKAFAOO_01795	1.85e-114	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MAKAFAOO_01796	3.69e-47	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKAFAOO_01797	6.01e-150	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MAKAFAOO_01798	3.23e-77	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MAKAFAOO_01799	1.42e-101	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MAKAFAOO_01800	4.11e-79	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MAKAFAOO_01801	5.96e-185	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MAKAFAOO_01802	2.26e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MAKAFAOO_01803	1.55e-214	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MAKAFAOO_01804	1.7e-163	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MAKAFAOO_01805	1.25e-23	-	-	-	K	-	-	-	AAA domain
MAKAFAOO_01806	2.4e-145	-	-	-	S	-	-	-	AAA domain
MAKAFAOO_01807	7.12e-147	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
MAKAFAOO_01808	7.82e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MAKAFAOO_01809	3.69e-12	-	-	-	L	-	-	-	hmm pf01527
MAKAFAOO_01811	1.11e-141	-	-	-	K	-	-	-	IrrE N-terminal-like domain
MAKAFAOO_01812	2.77e-27	-	-	-	-	-	-	-	-
MAKAFAOO_01813	1.75e-97	-	-	-	K	-	-	-	SIR2-like domain
MAKAFAOO_01814	7.29e-97	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MAKAFAOO_01815	9.83e-121	-	-	-	M	-	-	-	Glycosyl transferase family 8
MAKAFAOO_01816	9.34e-124	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MAKAFAOO_01817	2.73e-131	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
MAKAFAOO_01818	2.12e-60	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
MAKAFAOO_01819	8.21e-149	-	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MAKAFAOO_01820	3.74e-64	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MAKAFAOO_01821	5.35e-11	-	-	-	S	-	-	-	EpsG family
MAKAFAOO_01822	8.95e-60	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
MAKAFAOO_01823	2.28e-60	-	-	-	M	-	-	-	Glycosyl transferase family 2
MAKAFAOO_01824	2.28e-27	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
MAKAFAOO_01825	5.87e-17	-	-	-	E	-	-	-	Hexapeptide repeat of succinyl-transferase
MAKAFAOO_01826	1.6e-92	epsB	-	-	M	-	-	-	biosynthesis protein
MAKAFAOO_01827	4.48e-117	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MAKAFAOO_01828	5.99e-142	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MAKAFAOO_01829	4.69e-162	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAKAFAOO_01830	4.85e-115	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
MAKAFAOO_01831	8.14e-125	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
MAKAFAOO_01832	5.78e-249	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MAKAFAOO_01833	1.12e-62	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase, family 2
MAKAFAOO_01834	7.47e-202	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MAKAFAOO_01835	1.12e-70	-	-	-	-	-	-	-	-
MAKAFAOO_01836	2.85e-93	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MAKAFAOO_01837	1.36e-81	-	-	-	D	-	-	-	Peptidase family M23
MAKAFAOO_01839	1.62e-170	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
MAKAFAOO_01840	1.24e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MAKAFAOO_01841	3.23e-269	potE	-	-	E	-	-	-	Amino Acid
MAKAFAOO_01842	2e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKAFAOO_01843	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_01844	4.08e-56	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MAKAFAOO_01845	1.84e-169	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MAKAFAOO_01846	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MAKAFAOO_01849	4.37e-97	-	-	-	-	-	-	-	-
MAKAFAOO_01850	1.19e-29	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
MAKAFAOO_01851	7.7e-143	-	-	-	M	-	-	-	Glycosyl transferase family 2
MAKAFAOO_01852	1.57e-30	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
MAKAFAOO_01853	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MAKAFAOO_01854	7.97e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MAKAFAOO_01855	4.63e-120	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MAKAFAOO_01856	8.69e-86	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MAKAFAOO_01857	5.89e-196	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MAKAFAOO_01858	1.13e-61	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
MAKAFAOO_01859	5.23e-186	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MAKAFAOO_01860	1.07e-33	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MAKAFAOO_01861	4.55e-20	-	-	-	-	-	-	-	-
MAKAFAOO_01862	2.95e-89	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MAKAFAOO_01863	2.12e-120	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MAKAFAOO_01864	2.91e-150	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
MAKAFAOO_01866	1.22e-179	XK27_08315	-	-	M	-	-	-	Sulfatase
MAKAFAOO_01867	3.32e-10	-	-	-	G	-	-	-	Peptidase_C39 like family
MAKAFAOO_01868	2.85e-86	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MAKAFAOO_01875	1.56e-53	-	-	-	L	-	-	-	Resolvase, N terminal domain
MAKAFAOO_01876	3.73e-10	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
MAKAFAOO_01877	1.88e-185	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MAKAFAOO_01878	1.57e-270	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MAKAFAOO_01879	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MAKAFAOO_01880	2.24e-228	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MAKAFAOO_01881	8.44e-145	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
MAKAFAOO_01882	1.53e-74	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
MAKAFAOO_01883	4.08e-67	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MAKAFAOO_01884	2.88e-16	-	-	-	M	-	-	-	Glycosyl transferase family 2
MAKAFAOO_01885	1.11e-27	-	-	-	-	-	-	-	-
MAKAFAOO_01886	1.08e-111	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MAKAFAOO_01887	2.55e-69	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MAKAFAOO_01888	4.91e-115	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MAKAFAOO_01889	5.62e-92	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MAKAFAOO_01890	3.33e-76	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MAKAFAOO_01891	1.54e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MAKAFAOO_01892	2e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MAKAFAOO_01893	9.36e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MAKAFAOO_01894	4.42e-50	-	-	-	E	ko:K08234	-	ko00000	glyoxalase bleomycin resistance protein dioxygenase
MAKAFAOO_01895	6.04e-90	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MAKAFAOO_01896	2.96e-148	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MAKAFAOO_01897	1.51e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
MAKAFAOO_01898	1.52e-120	baeS	-	-	T	-	-	-	Histidine kinase
MAKAFAOO_01899	2.17e-101	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
MAKAFAOO_01900	1.36e-193	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MAKAFAOO_01901	1.69e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
MAKAFAOO_01902	8.07e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MAKAFAOO_01903	1.13e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MAKAFAOO_01904	3.58e-89	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MAKAFAOO_01905	1.93e-162	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MAKAFAOO_01906	2.23e-209	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKAFAOO_01907	1.36e-96	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
MAKAFAOO_01908	2.22e-44	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MAKAFAOO_01909	1.03e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
MAKAFAOO_01910	2.01e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
MAKAFAOO_01911	1.23e-08	-	-	-	S	-	-	-	Putative adhesin
MAKAFAOO_01912	8.46e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MAKAFAOO_01915	8.33e-296	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MAKAFAOO_01916	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
MAKAFAOO_01917	3.27e-130	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MAKAFAOO_01918	8.99e-212	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MAKAFAOO_01919	5.47e-153	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKAFAOO_01920	1.26e-132	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MAKAFAOO_01921	1.19e-201	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKAFAOO_01922	5.57e-169	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MAKAFAOO_01923	1.38e-146	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MAKAFAOO_01924	4.7e-137	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_01925	8.71e-88	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MAKAFAOO_01926	4.64e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAKAFAOO_01927	6.13e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MAKAFAOO_01928	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MAKAFAOO_01929	1.28e-130	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
MAKAFAOO_01930	1.99e-70	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKAFAOO_01931	4.53e-61	-	-	-	C	-	-	-	Flavodoxin
MAKAFAOO_01932	1.03e-59	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
MAKAFAOO_01933	2.06e-177	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MAKAFAOO_01934	2.56e-136	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MAKAFAOO_01935	3.76e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MAKAFAOO_01936	5.23e-119	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKAFAOO_01937	2.27e-168	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MAKAFAOO_01938	1.15e-106	-	-	-	C	-	-	-	nitroreductase
MAKAFAOO_01939	1.77e-105	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
MAKAFAOO_01940	1.16e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
MAKAFAOO_01941	1.05e-214	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MAKAFAOO_01942	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MAKAFAOO_01944	6.24e-192	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MAKAFAOO_01945	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKAFAOO_01946	3.63e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MAKAFAOO_01947	1.31e-272	-	-	-	-	-	-	-	-
MAKAFAOO_01948	2.57e-36	-	-	-	S	ko:K06940	-	ko00000	metal cluster binding
MAKAFAOO_01949	1.24e-135	-	-	-	-	-	-	-	-
MAKAFAOO_01950	2.69e-63	-	-	-	S	-	-	-	Tellurite resistance protein TerB
MAKAFAOO_01951	9.8e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
MAKAFAOO_01955	1.25e-305	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MAKAFAOO_01956	1.23e-22	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec system protein Asp3
MAKAFAOO_01957	6.79e-129	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system protein Asp2
MAKAFAOO_01958	4.11e-110	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
MAKAFAOO_01959	7.43e-75	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
MAKAFAOO_01960	4.19e-176	-	-	-	S	-	-	-	interspecies interaction between organisms
MAKAFAOO_01961	8.25e-262	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
MAKAFAOO_01962	2.75e-94	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MAKAFAOO_01963	1.16e-187	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MAKAFAOO_01964	1.62e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MAKAFAOO_01965	2.9e-134	ebh	-	-	D	-	-	-	interspecies interaction between organisms
MAKAFAOO_01966	3.35e-100	yycI	-	-	S	-	-	-	YycH protein
MAKAFAOO_01967	1.73e-124	yycH	-	-	S	-	-	-	YycH protein
MAKAFAOO_01968	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAKAFAOO_01969	2.43e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MAKAFAOO_01970	2.73e-133	yxeH	-	-	S	-	-	-	hydrolase
MAKAFAOO_01971	1.63e-198	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	FMN-dependent dehydrogenase
MAKAFAOO_01972	4.16e-212	-	-	-	EGP	-	-	-	Mycoplasma MFS transporter
MAKAFAOO_01973	3.36e-288	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MAKAFAOO_01974	6.18e-269	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_01975	2.33e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MAKAFAOO_01976	4.8e-220	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MAKAFAOO_01977	8.92e-27	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MAKAFAOO_01978	2.25e-20	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MAKAFAOO_01979	7.18e-81	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MAKAFAOO_01980	1.14e-175	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
MAKAFAOO_01982	1.98e-39	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MAKAFAOO_01983	5.56e-279	pepF	-	-	E	-	-	-	Oligopeptidase F
MAKAFAOO_01984	6.66e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
MAKAFAOO_01985	5.14e-89	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MAKAFAOO_01986	1.31e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
MAKAFAOO_01987	3.63e-140	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MAKAFAOO_01988	1.56e-11	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKAFAOO_01989	3e-191	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MAKAFAOO_01990	9.05e-126	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MAKAFAOO_01991	6.19e-283	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MAKAFAOO_01992	5.06e-290	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAKAFAOO_01993	3.94e-22	yneR	-	-	-	-	-	-	-
MAKAFAOO_01994	1.61e-307	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MAKAFAOO_01995	5.27e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MAKAFAOO_01996	2.81e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MAKAFAOO_01997	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MAKAFAOO_01998	4.83e-83	-	-	-	D	-	-	-	peptidase
MAKAFAOO_01999	6.63e-148	-	-	-	S	-	-	-	Glycosyl transferase family 2
MAKAFAOO_02000	2.13e-140	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
MAKAFAOO_02001	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MAKAFAOO_02002	7.54e-88	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAKAFAOO_02003	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MAKAFAOO_02004	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAKAFAOO_02005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAKAFAOO_02006	2.93e-194	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAKAFAOO_02007	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MAKAFAOO_02008	1.27e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MAKAFAOO_02009	1.82e-256	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAKAFAOO_02010	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MAKAFAOO_02011	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MAKAFAOO_02012	3.1e-137	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAKAFAOO_02013	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
MAKAFAOO_02014	1.17e-152	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MAKAFAOO_02015	4.42e-68	-	-	-	K	-	-	-	LysR substrate binding domain
MAKAFAOO_02017	1.7e-84	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
MAKAFAOO_02018	1.48e-40	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MAKAFAOO_02019	1.94e-136	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MAKAFAOO_02020	1.92e-159	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKAFAOO_02021	1.65e-188	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKAFAOO_02022	5.59e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MAKAFAOO_02023	1.29e-251	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MAKAFAOO_02024	9.08e-195	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MAKAFAOO_02025	3.73e-148	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MAKAFAOO_02026	5.91e-61	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MAKAFAOO_02027	1.3e-176	arcT	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
MAKAFAOO_02028	5.46e-115	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MAKAFAOO_02029	1.9e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MAKAFAOO_02030	3.78e-169	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MAKAFAOO_02031	4.87e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MAKAFAOO_02032	4.9e-131	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MAKAFAOO_02033	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAKAFAOO_02034	1.85e-161	-	-	-	-	-	-	-	-
MAKAFAOO_02035	2.17e-190	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MAKAFAOO_02036	8.38e-54	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
MAKAFAOO_02037	3.81e-40	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKAFAOO_02038	5.19e-130	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MAKAFAOO_02039	1.19e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MAKAFAOO_02040	1.6e-128	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MAKAFAOO_02041	6.62e-216	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MAKAFAOO_02042	2.75e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MAKAFAOO_02043	0.0	-	-	-	L	-	-	-	DNA helicase
MAKAFAOO_02045	1.77e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MAKAFAOO_02046	2.31e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MAKAFAOO_02047	1.2e-67	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
MAKAFAOO_02048	2.62e-59	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
MAKAFAOO_02049	1.29e-11	-	-	-	-	-	-	-	-
MAKAFAOO_02050	6.79e-317	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MAKAFAOO_02051	3.25e-280	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_02052	4.44e-44	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKAFAOO_02053	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKAFAOO_02054	1.1e-277	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MAKAFAOO_02055	3.91e-188	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MAKAFAOO_02056	3.9e-111	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MAKAFAOO_02057	1.51e-190	hpk31	-	-	T	-	-	-	Histidine kinase
MAKAFAOO_02058	1.21e-145	vanR	-	-	K	-	-	-	response regulator
MAKAFAOO_02059	1.11e-105	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MAKAFAOO_02060	2.76e-117	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MAKAFAOO_02061	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MAKAFAOO_02062	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MAKAFAOO_02063	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MAKAFAOO_02064	6.22e-29	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MAKAFAOO_02065	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAKAFAOO_02066	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAKAFAOO_02067	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MAKAFAOO_02068	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MAKAFAOO_02070	6.07e-152	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MAKAFAOO_02071	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MAKAFAOO_02072	2.25e-198	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MAKAFAOO_02073	5.35e-235	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MAKAFAOO_02074	3.41e-166	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family