ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NEHPDDFL_00001 3.59e-123 - - - V - - - VanZ like family
NEHPDDFL_00002 1.87e-249 - - - V - - - Beta-lactamase
NEHPDDFL_00003 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NEHPDDFL_00004 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEHPDDFL_00005 8.93e-71 - - - S - - - Pfam:DUF59
NEHPDDFL_00006 4.27e-223 ydhF - - S - - - Aldo keto reductase
NEHPDDFL_00007 2.42e-127 - - - FG - - - HIT domain
NEHPDDFL_00008 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NEHPDDFL_00009 4.29e-101 - - - - - - - -
NEHPDDFL_00010 1.3e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NEHPDDFL_00011 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
NEHPDDFL_00012 0.0 cadA - - P - - - P-type ATPase
NEHPDDFL_00014 8.45e-86 - - - S - - - YjbR
NEHPDDFL_00015 7.83e-284 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NEHPDDFL_00016 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NEHPDDFL_00017 7.12e-256 glmS2 - - M - - - SIS domain
NEHPDDFL_00018 1.56e-29 - - - S - - - Belongs to the LOG family
NEHPDDFL_00019 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NEHPDDFL_00020 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NEHPDDFL_00021 2.65e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHPDDFL_00022 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
NEHPDDFL_00023 2.28e-190 - - - GM - - - NmrA-like family
NEHPDDFL_00024 4.31e-86 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
NEHPDDFL_00025 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
NEHPDDFL_00026 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
NEHPDDFL_00027 1.7e-70 - - - - - - - -
NEHPDDFL_00028 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
NEHPDDFL_00029 2.11e-82 - - - - - - - -
NEHPDDFL_00030 9.16e-111 - - - - - - - -
NEHPDDFL_00031 4.58e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NEHPDDFL_00032 4.59e-74 - - - - - - - -
NEHPDDFL_00033 4.79e-21 - - - - - - - -
NEHPDDFL_00034 3.57e-150 - - - GM - - - NmrA-like family
NEHPDDFL_00035 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
NEHPDDFL_00036 1.63e-203 - - - EG - - - EamA-like transporter family
NEHPDDFL_00037 2.66e-155 - - - S - - - membrane
NEHPDDFL_00038 1.47e-144 - - - S - - - VIT family
NEHPDDFL_00039 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NEHPDDFL_00040 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NEHPDDFL_00041 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NEHPDDFL_00042 4.26e-54 - - - - - - - -
NEHPDDFL_00043 2.07e-97 - - - S - - - COG NOG18757 non supervised orthologous group
NEHPDDFL_00044 8.8e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
NEHPDDFL_00045 7.21e-35 - - - - - - - -
NEHPDDFL_00046 4.39e-66 - - - - - - - -
NEHPDDFL_00047 8.75e-85 - - - S - - - Protein of unknown function (DUF1398)
NEHPDDFL_00048 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NEHPDDFL_00049 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NEHPDDFL_00050 9.92e-230 ybcH - - D ko:K06889 - ko00000 Alpha beta
NEHPDDFL_00051 6.1e-101 - - - K - - - Domain of unknown function (DUF1836)
NEHPDDFL_00052 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NEHPDDFL_00053 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
NEHPDDFL_00054 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NEHPDDFL_00055 2.8e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NEHPDDFL_00056 1.36e-209 yvgN - - C - - - Aldo keto reductase
NEHPDDFL_00057 2.57e-171 - - - S - - - Putative threonine/serine exporter
NEHPDDFL_00058 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
NEHPDDFL_00059 1.05e-56 - - - S - - - Protein of unknown function (DUF1093)
NEHPDDFL_00060 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEHPDDFL_00061 5.94e-118 ymdB - - S - - - Macro domain protein
NEHPDDFL_00062 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
NEHPDDFL_00063 1.58e-66 - - - - - - - -
NEHPDDFL_00064 2.41e-212 - - - S - - - Protein of unknown function (DUF1002)
NEHPDDFL_00065 0.0 - - - - - - - -
NEHPDDFL_00066 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
NEHPDDFL_00067 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
NEHPDDFL_00068 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
NEHPDDFL_00069 5.33e-114 - - - K - - - Winged helix DNA-binding domain
NEHPDDFL_00070 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_00071 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
NEHPDDFL_00072 4.45e-38 - - - - - - - -
NEHPDDFL_00073 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
NEHPDDFL_00074 3.31e-106 - - - M - - - PFAM NLP P60 protein
NEHPDDFL_00075 4.7e-66 - - - - - - - -
NEHPDDFL_00076 2.35e-80 - - - - - - - -
NEHPDDFL_00079 5.05e-232 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NEHPDDFL_00080 3.42e-174 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NEHPDDFL_00081 3.04e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
NEHPDDFL_00082 1.45e-234 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NEHPDDFL_00083 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
NEHPDDFL_00084 9.44e-183 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEHPDDFL_00085 9.52e-72 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
NEHPDDFL_00086 6.85e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
NEHPDDFL_00087 1.01e-26 - - - - - - - -
NEHPDDFL_00088 2.03e-124 dpsB - - P - - - Belongs to the Dps family
NEHPDDFL_00089 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
NEHPDDFL_00090 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
NEHPDDFL_00091 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NEHPDDFL_00092 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEHPDDFL_00093 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NEHPDDFL_00094 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NEHPDDFL_00095 7.47e-235 - - - S - - - Cell surface protein
NEHPDDFL_00096 8.67e-160 - - - S - - - WxL domain surface cell wall-binding
NEHPDDFL_00097 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
NEHPDDFL_00098 7.83e-60 - - - - - - - -
NEHPDDFL_00099 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
NEHPDDFL_00100 1.03e-65 - - - - - - - -
NEHPDDFL_00101 0.0 - - - S - - - Putative metallopeptidase domain
NEHPDDFL_00102 4.03e-283 - - - S - - - associated with various cellular activities
NEHPDDFL_00103 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEHPDDFL_00104 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
NEHPDDFL_00105 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEHPDDFL_00106 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NEHPDDFL_00107 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
NEHPDDFL_00108 4.73e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NEHPDDFL_00109 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NEHPDDFL_00110 3.03e-295 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NEHPDDFL_00111 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NEHPDDFL_00112 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
NEHPDDFL_00113 7.48e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
NEHPDDFL_00114 1.59e-129 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NEHPDDFL_00115 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NEHPDDFL_00116 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NEHPDDFL_00117 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NEHPDDFL_00118 5.14e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NEHPDDFL_00119 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NEHPDDFL_00120 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEHPDDFL_00121 2.72e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
NEHPDDFL_00122 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NEHPDDFL_00123 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NEHPDDFL_00124 4.27e-253 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NEHPDDFL_00125 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NEHPDDFL_00126 8.93e-249 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NEHPDDFL_00127 4.07e-85 - - - S - - - pyridoxamine 5-phosphate
NEHPDDFL_00128 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEHPDDFL_00129 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEHPDDFL_00130 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NEHPDDFL_00131 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEHPDDFL_00132 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
NEHPDDFL_00133 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
NEHPDDFL_00134 1.71e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEHPDDFL_00135 8.13e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEHPDDFL_00136 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NEHPDDFL_00137 9.22e-211 - - - G - - - Xylose isomerase-like TIM barrel
NEHPDDFL_00138 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
NEHPDDFL_00139 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
NEHPDDFL_00140 2.09e-83 - - - - - - - -
NEHPDDFL_00141 2.63e-200 estA - - S - - - Putative esterase
NEHPDDFL_00142 5.44e-174 - - - K - - - UTRA domain
NEHPDDFL_00143 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_00144 1.25e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NEHPDDFL_00145 1.76e-204 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
NEHPDDFL_00146 2.64e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NEHPDDFL_00147 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_00148 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHPDDFL_00149 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEHPDDFL_00150 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_00151 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_00152 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHPDDFL_00153 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEHPDDFL_00154 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NEHPDDFL_00155 2.66e-222 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
NEHPDDFL_00156 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NEHPDDFL_00157 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NEHPDDFL_00159 1.15e-236 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEHPDDFL_00160 9e-187 yxeH - - S - - - hydrolase
NEHPDDFL_00161 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NEHPDDFL_00162 8.34e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NEHPDDFL_00163 1.43e-306 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEHPDDFL_00164 2.97e-60 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
NEHPDDFL_00165 1.58e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHPDDFL_00166 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHPDDFL_00167 4.53e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
NEHPDDFL_00168 5.26e-247 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
NEHPDDFL_00169 8.37e-296 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEHPDDFL_00170 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEHPDDFL_00171 1.1e-103 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHPDDFL_00172 3.05e-161 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
NEHPDDFL_00173 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NEHPDDFL_00174 1.09e-66 yueI - - S - - - Protein of unknown function (DUF1694)
NEHPDDFL_00175 4.84e-14 yueI - - S - - - Protein of unknown function (DUF1694)
NEHPDDFL_00176 6.83e-133 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NEHPDDFL_00177 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NEHPDDFL_00178 1.06e-175 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NEHPDDFL_00179 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
NEHPDDFL_00180 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEHPDDFL_00181 1.2e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
NEHPDDFL_00182 1.53e-179 - - - K - - - Helix-turn-helix domain, rpiR family
NEHPDDFL_00183 6.47e-95 - - - S - - - Protein of unknown function (DUF1694)
NEHPDDFL_00184 2.54e-210 - - - I - - - alpha/beta hydrolase fold
NEHPDDFL_00185 1.65e-206 - - - I - - - alpha/beta hydrolase fold
NEHPDDFL_00186 0.0 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEHPDDFL_00187 4.01e-263 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEHPDDFL_00188 3.83e-174 - - - G - - - Xylose isomerase domain protein TIM barrel
NEHPDDFL_00189 2.93e-200 nanK - - GK - - - ROK family
NEHPDDFL_00190 1.86e-210 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NEHPDDFL_00191 3.53e-158 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NEHPDDFL_00192 2.28e-291 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
NEHPDDFL_00193 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
NEHPDDFL_00194 1.22e-115 - - - T - - - ECF transporter, substrate-specific component
NEHPDDFL_00195 1.06e-16 - - - - - - - -
NEHPDDFL_00196 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
NEHPDDFL_00197 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
NEHPDDFL_00198 5.38e-101 nrp - - K ko:K16509 - ko00000 ArsC family
NEHPDDFL_00199 4.29e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEHPDDFL_00200 7.01e-286 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEHPDDFL_00201 3.82e-24 - - - - - - - -
NEHPDDFL_00202 2.49e-126 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
NEHPDDFL_00203 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
NEHPDDFL_00205 8.03e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NEHPDDFL_00206 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEHPDDFL_00207 5.03e-95 - - - K - - - Transcriptional regulator
NEHPDDFL_00208 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEHPDDFL_00209 4.04e-94 yueI - - S - - - Protein of unknown function (DUF1694)
NEHPDDFL_00210 1.45e-162 - - - S - - - Membrane
NEHPDDFL_00211 1.31e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NEHPDDFL_00212 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
NEHPDDFL_00213 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NEHPDDFL_00214 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NEHPDDFL_00215 4.67e-314 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
NEHPDDFL_00216 8.35e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
NEHPDDFL_00217 1.05e-179 - - - K - - - DeoR C terminal sensor domain
NEHPDDFL_00218 1.46e-60 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEHPDDFL_00219 1.1e-125 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEHPDDFL_00220 8.3e-39 - - - L ko:K07487 - ko00000 Transposase
NEHPDDFL_00221 3.38e-136 - - - L ko:K07487 - ko00000 Transposase
NEHPDDFL_00222 1.03e-168 - - - L ko:K07487 - ko00000 Transposase
NEHPDDFL_00224 1.08e-208 - - - - - - - -
NEHPDDFL_00225 2.76e-28 - - - S - - - Cell surface protein
NEHPDDFL_00228 1.48e-07 - - - L - - - Helix-turn-helix domain
NEHPDDFL_00229 4.32e-16 - - - L - - - Helix-turn-helix domain
NEHPDDFL_00230 4.04e-23 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEHPDDFL_00231 2.15e-17 - - - M - - - Domain of unknown function (DUF5011)
NEHPDDFL_00233 3.07e-06 - - - D - - - Mycoplasma protein of unknown function, DUF285
NEHPDDFL_00235 2.72e-70 - - - K - - - helix_turn_helix, arabinose operon control protein
NEHPDDFL_00237 2.12e-27 - - - L ko:K07487 - ko00000 Transposase
NEHPDDFL_00238 9.07e-22 - - - L ko:K07487 - ko00000 Transposase
NEHPDDFL_00239 5.84e-50 - - - M - - - Domain of unknown function (DUF5011)
NEHPDDFL_00240 9.95e-122 - - - M - - - Glycosyl hydrolases family 25
NEHPDDFL_00241 1.28e-35 - - - S - - - L,D-transpeptidase catalytic domain
NEHPDDFL_00242 3.95e-92 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
NEHPDDFL_00243 0.0 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_00244 4.02e-205 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEHPDDFL_00245 0.0 - 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
NEHPDDFL_00246 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
NEHPDDFL_00247 1.54e-247 - - - K - - - Transcriptional regulator
NEHPDDFL_00248 0.0 ypdD - - G - - - Glycosyl hydrolase family 92
NEHPDDFL_00249 1.09e-275 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEHPDDFL_00250 3.76e-212 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NEHPDDFL_00251 0.0 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
NEHPDDFL_00252 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEHPDDFL_00253 1.71e-139 ypcB - - S - - - integral membrane protein
NEHPDDFL_00254 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
NEHPDDFL_00255 0.0 ypcG - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Domain of unknown function (DUF3502)
NEHPDDFL_00256 6.47e-213 lplC - - U ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHPDDFL_00257 1.29e-231 ypdA - - U ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHPDDFL_00258 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
NEHPDDFL_00259 9.5e-200 - - - K - - - helix_turn_helix, arabinose operon control protein
NEHPDDFL_00260 0.0 mdlA2 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NEHPDDFL_00261 0.0 yknV - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_00262 1.48e-247 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
NEHPDDFL_00263 1.91e-201 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NEHPDDFL_00264 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NEHPDDFL_00265 3.55e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
NEHPDDFL_00266 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
NEHPDDFL_00267 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
NEHPDDFL_00268 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NEHPDDFL_00269 2.21e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
NEHPDDFL_00270 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
NEHPDDFL_00271 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NEHPDDFL_00272 3.87e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEHPDDFL_00273 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NEHPDDFL_00274 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NEHPDDFL_00275 2.51e-103 - - - T - - - Universal stress protein family
NEHPDDFL_00276 7.43e-130 padR - - K - - - Virulence activator alpha C-term
NEHPDDFL_00277 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NEHPDDFL_00278 3.79e-181 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
NEHPDDFL_00279 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
NEHPDDFL_00280 4.02e-203 degV1 - - S - - - DegV family
NEHPDDFL_00281 5.83e-80 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
NEHPDDFL_00282 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NEHPDDFL_00284 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEHPDDFL_00285 0.0 - - - - - - - -
NEHPDDFL_00287 1.1e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
NEHPDDFL_00288 3.21e-144 - - - S - - - Cell surface protein
NEHPDDFL_00289 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEHPDDFL_00290 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEHPDDFL_00291 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
NEHPDDFL_00292 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
NEHPDDFL_00293 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHPDDFL_00294 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEHPDDFL_00295 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEHPDDFL_00296 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEHPDDFL_00297 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEHPDDFL_00298 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
NEHPDDFL_00299 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEHPDDFL_00300 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEHPDDFL_00301 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEHPDDFL_00302 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NEHPDDFL_00303 4.13e-109 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEHPDDFL_00304 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEHPDDFL_00305 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NEHPDDFL_00306 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NEHPDDFL_00307 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NEHPDDFL_00308 4.96e-289 yttB - - EGP - - - Major Facilitator
NEHPDDFL_00309 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEHPDDFL_00310 3.25e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEHPDDFL_00312 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHPDDFL_00314 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEHPDDFL_00315 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NEHPDDFL_00316 2.02e-268 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NEHPDDFL_00317 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NEHPDDFL_00318 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEHPDDFL_00319 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NEHPDDFL_00321 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
NEHPDDFL_00322 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NEHPDDFL_00323 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
NEHPDDFL_00324 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
NEHPDDFL_00325 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
NEHPDDFL_00326 2.54e-50 - - - - - - - -
NEHPDDFL_00328 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NEHPDDFL_00329 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEHPDDFL_00330 1.02e-312 yycH - - S - - - YycH protein
NEHPDDFL_00331 3.54e-195 yycI - - S - - - YycH protein
NEHPDDFL_00332 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NEHPDDFL_00333 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NEHPDDFL_00334 1.74e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEHPDDFL_00335 3.46e-124 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_00336 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
NEHPDDFL_00337 3.46e-156 ung2 - - L - - - Uracil-DNA glycosylase
NEHPDDFL_00338 2.24e-155 pnb - - C - - - nitroreductase
NEHPDDFL_00339 2.02e-85 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
NEHPDDFL_00340 5.25e-149 - - - S - - - Elongation factor G-binding protein, N-terminal
NEHPDDFL_00341 0.0 - - - C - - - FMN_bind
NEHPDDFL_00342 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NEHPDDFL_00343 1.46e-204 - - - K - - - LysR family
NEHPDDFL_00344 2.49e-95 - - - C - - - FMN binding
NEHPDDFL_00345 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEHPDDFL_00346 4.06e-211 - - - S - - - KR domain
NEHPDDFL_00347 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
NEHPDDFL_00348 5.07e-157 ydgI - - C - - - Nitroreductase family
NEHPDDFL_00349 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
NEHPDDFL_00350 3.83e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NEHPDDFL_00351 1.54e-248 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEHPDDFL_00352 0.0 - - - S - - - Putative threonine/serine exporter
NEHPDDFL_00353 3.97e-174 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEHPDDFL_00354 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
NEHPDDFL_00355 1.65e-106 - - - S - - - ASCH
NEHPDDFL_00356 3.06e-165 - - - F - - - glutamine amidotransferase
NEHPDDFL_00357 1.67e-220 - - - K - - - WYL domain
NEHPDDFL_00358 1.34e-151 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NEHPDDFL_00359 0.0 fusA1 - - J - - - elongation factor G
NEHPDDFL_00360 7.44e-51 - - - S - - - Protein of unknown function
NEHPDDFL_00361 1.9e-79 - - - S - - - Protein of unknown function
NEHPDDFL_00362 4.28e-195 - - - EG - - - EamA-like transporter family
NEHPDDFL_00363 7.65e-121 yfbM - - K - - - FR47-like protein
NEHPDDFL_00364 1.4e-162 - - - S - - - DJ-1/PfpI family
NEHPDDFL_00365 3.14e-230 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NEHPDDFL_00366 7.81e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPDDFL_00367 1.71e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
NEHPDDFL_00368 7.4e-214 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEHPDDFL_00369 1.06e-178 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NEHPDDFL_00370 2.38e-99 - - - - - - - -
NEHPDDFL_00371 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
NEHPDDFL_00372 4.85e-180 - - - - - - - -
NEHPDDFL_00373 4.07e-05 - - - - - - - -
NEHPDDFL_00374 7.9e-142 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NEHPDDFL_00375 1.67e-54 - - - - - - - -
NEHPDDFL_00376 7.11e-165 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_00377 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NEHPDDFL_00378 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NEHPDDFL_00379 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
NEHPDDFL_00380 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
NEHPDDFL_00381 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
NEHPDDFL_00382 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NEHPDDFL_00383 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
NEHPDDFL_00384 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEHPDDFL_00385 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
NEHPDDFL_00386 3.94e-224 - - - C - - - Zinc-binding dehydrogenase
NEHPDDFL_00388 6.51e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEHPDDFL_00389 1.68e-188 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NEHPDDFL_00390 2.68e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEHPDDFL_00391 9.14e-265 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NEHPDDFL_00392 7.45e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NEHPDDFL_00393 0.0 - - - L - - - HIRAN domain
NEHPDDFL_00394 3.55e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
NEHPDDFL_00395 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
NEHPDDFL_00396 1e-156 - - - - - - - -
NEHPDDFL_00397 2.94e-191 - - - I - - - Alpha/beta hydrolase family
NEHPDDFL_00398 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEHPDDFL_00399 8.08e-185 - - - F - - - Phosphorylase superfamily
NEHPDDFL_00400 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NEHPDDFL_00401 5.13e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NEHPDDFL_00402 1.05e-97 - - - K - - - Transcriptional regulator
NEHPDDFL_00403 3.28e-95 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NEHPDDFL_00404 1.8e-288 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NEHPDDFL_00405 2.21e-65 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPDDFL_00406 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
NEHPDDFL_00408 3.07e-204 morA - - S - - - reductase
NEHPDDFL_00409 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
NEHPDDFL_00410 3.19e-105 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
NEHPDDFL_00411 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NEHPDDFL_00412 2.65e-116 - - - - - - - -
NEHPDDFL_00413 0.0 - - - - - - - -
NEHPDDFL_00414 6.49e-268 - - - C - - - Oxidoreductase
NEHPDDFL_00415 2.21e-191 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NEHPDDFL_00416 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_00417 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
NEHPDDFL_00418 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NEHPDDFL_00419 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
NEHPDDFL_00420 3.14e-182 - - - - - - - -
NEHPDDFL_00421 1.35e-46 - - - - - - - -
NEHPDDFL_00422 3.59e-119 - - - - - - - -
NEHPDDFL_00423 3.37e-115 - - - - - - - -
NEHPDDFL_00424 7.14e-185 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
NEHPDDFL_00425 4.24e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_00426 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
NEHPDDFL_00427 9.77e-152 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NEHPDDFL_00428 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
NEHPDDFL_00429 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
NEHPDDFL_00431 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_00432 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
NEHPDDFL_00433 3.88e-239 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
NEHPDDFL_00434 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
NEHPDDFL_00435 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
NEHPDDFL_00436 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEHPDDFL_00437 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NEHPDDFL_00438 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
NEHPDDFL_00439 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
NEHPDDFL_00440 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEHPDDFL_00441 3.74e-302 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHPDDFL_00442 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_00443 1.75e-191 malA - - S - - - maltodextrose utilization protein MalA
NEHPDDFL_00444 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
NEHPDDFL_00445 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEHPDDFL_00446 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NEHPDDFL_00447 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
NEHPDDFL_00448 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
NEHPDDFL_00449 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NEHPDDFL_00450 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NEHPDDFL_00451 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHPDDFL_00452 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NEHPDDFL_00453 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
NEHPDDFL_00454 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEHPDDFL_00455 9.51e-210 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NEHPDDFL_00456 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NEHPDDFL_00457 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEHPDDFL_00458 5.99e-213 mleR - - K - - - LysR substrate binding domain
NEHPDDFL_00459 0.0 - - - M - - - domain protein
NEHPDDFL_00461 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NEHPDDFL_00462 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHPDDFL_00463 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHPDDFL_00464 2.65e-102 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEHPDDFL_00465 1.45e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHPDDFL_00466 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEHPDDFL_00467 6.7e-148 pgm1 - - G - - - phosphoglycerate mutase
NEHPDDFL_00468 4.12e-228 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
NEHPDDFL_00469 6.33e-46 - - - - - - - -
NEHPDDFL_00470 4.69e-79 - - - S - - - Domain of unknown function (DU1801)
NEHPDDFL_00471 1.53e-208 fbpA - - K - - - Domain of unknown function (DUF814)
NEHPDDFL_00472 1.5e-277 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEHPDDFL_00473 3.81e-18 - - - - - - - -
NEHPDDFL_00474 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEHPDDFL_00475 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEHPDDFL_00476 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
NEHPDDFL_00477 2.13e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
NEHPDDFL_00478 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEHPDDFL_00479 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
NEHPDDFL_00480 6.07e-117 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NEHPDDFL_00481 5.3e-202 dkgB - - S - - - reductase
NEHPDDFL_00482 1.28e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEHPDDFL_00483 1.2e-91 - - - - - - - -
NEHPDDFL_00484 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEHPDDFL_00486 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEHPDDFL_00487 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEHPDDFL_00488 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
NEHPDDFL_00489 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_00490 2.61e-282 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
NEHPDDFL_00491 1.71e-111 - - - - - - - -
NEHPDDFL_00492 1.96e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NEHPDDFL_00493 7.19e-68 - - - - - - - -
NEHPDDFL_00494 1.22e-125 - - - - - - - -
NEHPDDFL_00495 2.98e-90 - - - - - - - -
NEHPDDFL_00496 2.41e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NEHPDDFL_00497 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
NEHPDDFL_00498 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
NEHPDDFL_00499 3.26e-160 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
NEHPDDFL_00500 1.65e-295 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_00501 6.14e-53 - - - - - - - -
NEHPDDFL_00502 2.18e-268 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NEHPDDFL_00503 1.73e-269 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
NEHPDDFL_00504 5.06e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
NEHPDDFL_00505 1.22e-166 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
NEHPDDFL_00506 1.17e-244 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
NEHPDDFL_00507 4.3e-124 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
NEHPDDFL_00508 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NEHPDDFL_00509 7.54e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NEHPDDFL_00510 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NEHPDDFL_00511 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NEHPDDFL_00512 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
NEHPDDFL_00513 2.21e-56 - - - - - - - -
NEHPDDFL_00514 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NEHPDDFL_00515 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEHPDDFL_00516 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHPDDFL_00517 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEHPDDFL_00518 2.6e-185 - - - - - - - -
NEHPDDFL_00519 1.21e-94 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
NEHPDDFL_00520 4.5e-303 tagB 2.7.8.12, 2.7.8.45 - M ko:K09809,ko:K21591 - ko00000,ko01000 glycerophosphotransferase
NEHPDDFL_00521 0.0 tagF2 2.7.8.12 - H ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHPDDFL_00522 1.3e-203 - - - S - - - Psort location CytoplasmicMembrane, score
NEHPDDFL_00523 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NEHPDDFL_00524 7.84e-92 - - - - - - - -
NEHPDDFL_00525 8.9e-96 ywnA - - K - - - Transcriptional regulator
NEHPDDFL_00526 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_00527 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEHPDDFL_00528 1.34e-151 - - - - - - - -
NEHPDDFL_00529 2.92e-57 - - - - - - - -
NEHPDDFL_00530 1.55e-55 - - - - - - - -
NEHPDDFL_00531 0.0 ydiC - - EGP - - - Major Facilitator
NEHPDDFL_00532 8.98e-86 - - - K - - - helix_turn_helix, mercury resistance
NEHPDDFL_00533 4.54e-316 hpk2 - - T - - - Histidine kinase
NEHPDDFL_00534 1.1e-164 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
NEHPDDFL_00535 2.42e-65 - - - - - - - -
NEHPDDFL_00536 2.78e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
NEHPDDFL_00537 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_00538 3.35e-75 - - - - - - - -
NEHPDDFL_00539 2.87e-56 - - - - - - - -
NEHPDDFL_00540 7.18e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEHPDDFL_00541 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
NEHPDDFL_00542 1.49e-63 - - - - - - - -
NEHPDDFL_00543 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NEHPDDFL_00544 1.17e-135 - - - K - - - transcriptional regulator
NEHPDDFL_00545 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NEHPDDFL_00546 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NEHPDDFL_00547 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
NEHPDDFL_00548 1.84e-295 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NEHPDDFL_00549 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_00550 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_00551 5.54e-156 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_00552 3.16e-279 - - - S - - - Membrane
NEHPDDFL_00553 4.22e-59 - - - S - - - Protein of unknown function (DUF3781)
NEHPDDFL_00554 1.31e-139 yoaZ - - S - - - intracellular protease amidase
NEHPDDFL_00555 2.33e-56 - - - K - - - HxlR-like helix-turn-helix
NEHPDDFL_00556 4.18e-27 - - - - - - - -
NEHPDDFL_00557 1.37e-24 - - - - - - - -
NEHPDDFL_00558 2.06e-81 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_00559 5.31e-66 - - - K - - - Helix-turn-helix domain
NEHPDDFL_00560 5.49e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
NEHPDDFL_00561 2.4e-112 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
NEHPDDFL_00562 3.29e-154 yciB - - M - - - ErfK YbiS YcfS YnhG
NEHPDDFL_00563 5.7e-142 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEHPDDFL_00564 1.93e-139 - - - GM - - - NAD(P)H-binding
NEHPDDFL_00565 5.35e-102 - - - GM - - - SnoaL-like domain
NEHPDDFL_00566 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
NEHPDDFL_00567 2.52e-85 - - - S - - - Domain of unknown function (DUF4440)
NEHPDDFL_00568 7.9e-136 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_00569 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
NEHPDDFL_00570 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
NEHPDDFL_00572 6.79e-53 - - - - - - - -
NEHPDDFL_00573 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEHPDDFL_00574 1.6e-233 ydbI - - K - - - AI-2E family transporter
NEHPDDFL_00575 4.33e-265 xylR - - GK - - - ROK family
NEHPDDFL_00576 5.21e-151 - - - - - - - -
NEHPDDFL_00577 4.45e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NEHPDDFL_00578 1.41e-211 - - - - - - - -
NEHPDDFL_00579 2.76e-258 pkn2 - - KLT - - - Protein tyrosine kinase
NEHPDDFL_00580 5.03e-37 - - - S - - - Protein of unknown function (DUF4064)
NEHPDDFL_00581 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
NEHPDDFL_00582 9.69e-99 - - - S - - - Psort location Cytoplasmic, score
NEHPDDFL_00583 1.49e-72 - - - - - - - -
NEHPDDFL_00584 9.65e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
NEHPDDFL_00585 5.93e-73 - - - S - - - branched-chain amino acid
NEHPDDFL_00586 2.05e-167 - - - E - - - branched-chain amino acid
NEHPDDFL_00587 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NEHPDDFL_00588 5.36e-305 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NEHPDDFL_00589 5.61e-273 hpk31 - - T - - - Histidine kinase
NEHPDDFL_00590 1.14e-159 vanR - - K - - - response regulator
NEHPDDFL_00591 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
NEHPDDFL_00592 3.84e-207 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEHPDDFL_00593 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEHPDDFL_00594 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
NEHPDDFL_00595 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEHPDDFL_00596 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NEHPDDFL_00597 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEHPDDFL_00598 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NEHPDDFL_00599 6.07e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEHPDDFL_00600 4.27e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NEHPDDFL_00601 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
NEHPDDFL_00602 1.1e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHPDDFL_00603 3.36e-216 - - - K - - - LysR substrate binding domain
NEHPDDFL_00604 2.07e-302 - - - EK - - - Aminotransferase, class I
NEHPDDFL_00605 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NEHPDDFL_00606 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_00607 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_00608 1.2e-175 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NEHPDDFL_00609 1.78e-126 - - - KT - - - response to antibiotic
NEHPDDFL_00610 1.72e-69 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
NEHPDDFL_00611 1.73e-132 - - - S - - - Protein of unknown function (DUF1700)
NEHPDDFL_00612 4.3e-205 - - - S - - - Putative adhesin
NEHPDDFL_00613 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHPDDFL_00614 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NEHPDDFL_00615 1.06e-232 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NEHPDDFL_00616 4.35e-262 - - - S - - - DUF218 domain
NEHPDDFL_00617 1.16e-163 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
NEHPDDFL_00618 7.19e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_00619 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEHPDDFL_00620 6.26e-101 - - - - - - - -
NEHPDDFL_00621 4.17e-263 - 4.1.1.45 - E ko:K03392,ko:K07045 ko00380,ko01100,map00380,map01100 ko00000,ko00001,ko00002,ko01000 amidohydrolase
NEHPDDFL_00622 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHPDDFL_00623 2.01e-307 - - - S - - - Neutral/alkaline non-lysosomal ceramidase, N-terminal
NEHPDDFL_00624 1.1e-297 - - - - - - - -
NEHPDDFL_00625 3.91e-211 - - - K - - - LysR substrate binding domain
NEHPDDFL_00626 6.9e-197 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
NEHPDDFL_00627 3.03e-191 - - - S - - - haloacid dehalogenase-like hydrolase
NEHPDDFL_00628 3.75e-103 - - - K - - - MerR family regulatory protein
NEHPDDFL_00629 3.9e-202 - - - GM - - - NmrA-like family
NEHPDDFL_00630 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NEHPDDFL_00631 5.08e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
NEHPDDFL_00633 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
NEHPDDFL_00634 6.93e-303 - - - S - - - module of peptide synthetase
NEHPDDFL_00635 1.78e-139 - - - - - - - -
NEHPDDFL_00636 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NEHPDDFL_00637 7.43e-77 - - - S - - - Enterocin A Immunity
NEHPDDFL_00638 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
NEHPDDFL_00639 1.54e-214 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
NEHPDDFL_00640 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
NEHPDDFL_00641 9.76e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
NEHPDDFL_00642 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
NEHPDDFL_00643 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
NEHPDDFL_00644 1.03e-34 - - - - - - - -
NEHPDDFL_00645 1.48e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
NEHPDDFL_00646 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
NEHPDDFL_00647 8.52e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
NEHPDDFL_00648 2.71e-234 - - - D ko:K06889 - ko00000 Alpha beta
NEHPDDFL_00649 2.31e-95 - - - M - - - LysM domain protein
NEHPDDFL_00650 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
NEHPDDFL_00651 1.01e-225 - - - - - - - -
NEHPDDFL_00652 2.8e-169 - - - - - - - -
NEHPDDFL_00653 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
NEHPDDFL_00654 3.01e-75 - - - - - - - -
NEHPDDFL_00655 1.3e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEHPDDFL_00656 7.61e-102 - - - S ko:K02348 - ko00000 GNAT family
NEHPDDFL_00657 1.24e-99 - - - K - - - Transcriptional regulator
NEHPDDFL_00658 3.91e-287 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NEHPDDFL_00659 6.01e-51 - - - - - - - -
NEHPDDFL_00661 1.04e-35 - - - - - - - -
NEHPDDFL_00662 9.25e-32 - - - U - - - Preprotein translocase subunit SecB
NEHPDDFL_00663 3.07e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_00664 1.31e-179 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_00665 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_00666 5.94e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NEHPDDFL_00667 3.68e-125 - - - K - - - Cupin domain
NEHPDDFL_00668 8.08e-110 - - - S - - - ASCH
NEHPDDFL_00669 1.88e-111 - - - K - - - GNAT family
NEHPDDFL_00670 2.14e-117 - - - K - - - acetyltransferase
NEHPDDFL_00671 2.06e-30 - - - - - - - -
NEHPDDFL_00672 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NEHPDDFL_00673 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_00674 1.08e-243 - - - - - - - -
NEHPDDFL_00675 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
NEHPDDFL_00676 1.16e-206 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NEHPDDFL_00678 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
NEHPDDFL_00679 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
NEHPDDFL_00680 7.28e-42 - - - - - - - -
NEHPDDFL_00681 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEHPDDFL_00682 6.4e-54 - - - - - - - -
NEHPDDFL_00683 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NEHPDDFL_00684 1.49e-227 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEHPDDFL_00685 1.45e-79 - - - S - - - CHY zinc finger
NEHPDDFL_00686 1.06e-143 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
NEHPDDFL_00687 7.98e-158 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEHPDDFL_00688 5.18e-115 metP_2 - - U ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHPDDFL_00689 5.67e-187 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEHPDDFL_00690 2.94e-282 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEHPDDFL_00691 5.25e-279 - - - - - - - -
NEHPDDFL_00692 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NEHPDDFL_00693 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NEHPDDFL_00694 3.93e-59 - - - - - - - -
NEHPDDFL_00695 1.61e-119 - - - K - - - Transcriptional regulator PadR-like family
NEHPDDFL_00696 0.0 - - - P - - - Major Facilitator Superfamily
NEHPDDFL_00697 1.05e-308 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NEHPDDFL_00698 5.43e-228 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NEHPDDFL_00699 1.05e-58 - - - - - - - -
NEHPDDFL_00700 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
NEHPDDFL_00701 1.44e-154 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NEHPDDFL_00702 0.0 sufI - - Q - - - Multicopper oxidase
NEHPDDFL_00703 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NEHPDDFL_00704 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NEHPDDFL_00705 1.96e-295 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NEHPDDFL_00706 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
NEHPDDFL_00707 1.52e-103 - - - - - - - -
NEHPDDFL_00708 2.43e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEHPDDFL_00709 3.66e-224 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NEHPDDFL_00710 1.07e-208 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPDDFL_00711 0.0 - - - - - - - -
NEHPDDFL_00712 1.42e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
NEHPDDFL_00713 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEHPDDFL_00714 9.02e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_00715 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NEHPDDFL_00716 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEHPDDFL_00717 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
NEHPDDFL_00718 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEHPDDFL_00719 0.0 - - - M - - - domain protein
NEHPDDFL_00720 2.36e-73 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
NEHPDDFL_00721 5.63e-49 - - - U - - - domain, Protein
NEHPDDFL_00722 1.82e-34 - - - S - - - Immunity protein 74
NEHPDDFL_00725 3.63e-218 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NEHPDDFL_00726 3.28e-229 cps3B - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
NEHPDDFL_00727 1.7e-283 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NEHPDDFL_00728 1.37e-260 cps3D - - - - - - -
NEHPDDFL_00729 3.55e-146 cps3E - - - - - - -
NEHPDDFL_00730 8.23e-208 cps3F - - - - - - -
NEHPDDFL_00731 3.17e-259 cps3H - - - - - - -
NEHPDDFL_00732 5.67e-257 cps3I - - G - - - Acyltransferase family
NEHPDDFL_00733 3.43e-189 cps3J - - M - - - Domain of unknown function (DUF4422)
NEHPDDFL_00734 6.86e-175 - - - K - - - helix_turn_helix, arabinose operon control protein
NEHPDDFL_00735 0.0 - - - M - - - domain protein
NEHPDDFL_00736 5.36e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEHPDDFL_00737 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NEHPDDFL_00738 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NEHPDDFL_00739 1.06e-68 - - - - - - - -
NEHPDDFL_00740 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
NEHPDDFL_00741 1.95e-41 - - - - - - - -
NEHPDDFL_00742 1.64e-35 - - - - - - - -
NEHPDDFL_00743 6.87e-131 - - - K - - - DNA-templated transcription, initiation
NEHPDDFL_00744 1.9e-168 - - - - - - - -
NEHPDDFL_00745 1.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NEHPDDFL_00746 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NEHPDDFL_00747 4.09e-172 lytE - - M - - - NlpC/P60 family
NEHPDDFL_00748 8.01e-64 - - - K - - - sequence-specific DNA binding
NEHPDDFL_00749 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
NEHPDDFL_00750 2.09e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NEHPDDFL_00751 1.13e-257 yueF - - S - - - AI-2E family transporter
NEHPDDFL_00752 2.46e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
NEHPDDFL_00753 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NEHPDDFL_00754 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NEHPDDFL_00755 1.94e-215 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NEHPDDFL_00756 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NEHPDDFL_00757 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NEHPDDFL_00758 0.0 - - - - - - - -
NEHPDDFL_00759 1.49e-252 - - - M - - - MucBP domain
NEHPDDFL_00760 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
NEHPDDFL_00761 1.14e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
NEHPDDFL_00762 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
NEHPDDFL_00763 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHPDDFL_00764 1.4e-209 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHPDDFL_00765 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHPDDFL_00766 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEHPDDFL_00767 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEHPDDFL_00768 3.4e-85 - - - K - - - Winged helix DNA-binding domain
NEHPDDFL_00769 2.5e-132 - - - L - - - Integrase
NEHPDDFL_00770 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
NEHPDDFL_00771 5.6e-41 - - - - - - - -
NEHPDDFL_00772 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NEHPDDFL_00773 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEHPDDFL_00774 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NEHPDDFL_00775 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NEHPDDFL_00776 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEHPDDFL_00777 6.56e-292 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NEHPDDFL_00778 1.22e-292 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEHPDDFL_00779 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
NEHPDDFL_00780 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEHPDDFL_00783 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NEHPDDFL_00784 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
NEHPDDFL_00787 4.58e-230 - - - L - - - Belongs to the 'phage' integrase family
NEHPDDFL_00789 1.08e-104 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
NEHPDDFL_00790 1.6e-55 - - - - - - - -
NEHPDDFL_00791 1.15e-05 - - - - - - - -
NEHPDDFL_00794 2.71e-38 - - - - - - - -
NEHPDDFL_00795 1.08e-172 - - - L - - - Primase C terminal 1 (PriCT-1)
NEHPDDFL_00796 0.0 - - - S - - - Virulence-associated protein E
NEHPDDFL_00797 7.55e-82 - - - - - - - -
NEHPDDFL_00798 1.25e-93 - - - - - - - -
NEHPDDFL_00800 4.5e-62 - - - - - - - -
NEHPDDFL_00801 2.89e-167 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NEHPDDFL_00802 2.8e-35 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NEHPDDFL_00803 0.0 ybeC - - E - - - amino acid
NEHPDDFL_00804 1.03e-206 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEHPDDFL_00806 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
NEHPDDFL_00807 2.78e-71 - - - S - - - Cupin domain
NEHPDDFL_00808 1.31e-213 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
NEHPDDFL_00809 2.52e-244 ysdE - - P - - - Citrate transporter
NEHPDDFL_00810 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NEHPDDFL_00811 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEHPDDFL_00812 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEHPDDFL_00813 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NEHPDDFL_00814 3.99e-177 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NEHPDDFL_00815 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEHPDDFL_00816 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NEHPDDFL_00817 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEHPDDFL_00818 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
NEHPDDFL_00819 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NEHPDDFL_00820 7.59e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NEHPDDFL_00821 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NEHPDDFL_00822 1.19e-201 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEHPDDFL_00824 4.54e-54 - - - - - - - -
NEHPDDFL_00826 8.83e-317 - - - EGP - - - Major Facilitator
NEHPDDFL_00827 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEHPDDFL_00828 4.26e-109 cvpA - - S - - - Colicin V production protein
NEHPDDFL_00829 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEHPDDFL_00830 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NEHPDDFL_00831 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
NEHPDDFL_00832 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NEHPDDFL_00833 3.47e-135 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
NEHPDDFL_00834 4.79e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
NEHPDDFL_00835 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NEHPDDFL_00837 2.77e-30 - - - - - - - -
NEHPDDFL_00839 1.63e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHPDDFL_00840 7.52e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NEHPDDFL_00841 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPDDFL_00842 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NEHPDDFL_00843 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NEHPDDFL_00844 1.02e-78 qacC - - P ko:K03297,ko:K11741,ko:K11815 - ko00000,ko00002,ko02000 Multidrug Resistance protein
NEHPDDFL_00845 6.1e-279 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NEHPDDFL_00846 1.54e-228 ydbI - - K - - - AI-2E family transporter
NEHPDDFL_00847 5.29e-212 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEHPDDFL_00848 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEHPDDFL_00850 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
NEHPDDFL_00851 9.7e-109 - - - - - - - -
NEHPDDFL_00853 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEHPDDFL_00854 2.5e-188 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEHPDDFL_00855 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEHPDDFL_00856 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEHPDDFL_00857 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NEHPDDFL_00858 2.49e-73 - - - S - - - Enterocin A Immunity
NEHPDDFL_00859 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NEHPDDFL_00860 4.27e-253 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NEHPDDFL_00861 0.0 - - - S - - - MucBP domain
NEHPDDFL_00862 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEHPDDFL_00863 1.29e-206 - - - K - - - LysR substrate binding domain
NEHPDDFL_00864 1.85e-201 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
NEHPDDFL_00865 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
NEHPDDFL_00866 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEHPDDFL_00867 3.41e-152 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_00868 2.83e-267 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NEHPDDFL_00869 1.87e-107 - - - S - - - WxL domain surface cell wall-binding
NEHPDDFL_00870 9.58e-29 - - - S - - - Bacterial protein of unknown function (DUF916)
NEHPDDFL_00871 7.11e-165 - - - S - - - Bacterial protein of unknown function (DUF916)
NEHPDDFL_00872 4.81e-80 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEHPDDFL_00874 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
NEHPDDFL_00875 3.74e-75 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
NEHPDDFL_00876 2.22e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
NEHPDDFL_00877 1.08e-65 - - - L - - - Integrase
NEHPDDFL_00878 1.53e-106 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
NEHPDDFL_00879 9.13e-70 - - - S - - - Bacterial mobilisation protein (MobC)
NEHPDDFL_00880 1.38e-231 - - - U - - - Relaxase/Mobilisation nuclease domain
NEHPDDFL_00881 9.81e-73 repA - - S - - - Replication initiator protein A
NEHPDDFL_00882 1.77e-56 - - - - - - - -
NEHPDDFL_00883 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NEHPDDFL_00884 1.45e-103 - - - L - - - Phage integrase family
NEHPDDFL_00885 1.24e-39 - - - - - - - -
NEHPDDFL_00886 5.12e-112 - - - - - - - -
NEHPDDFL_00887 5.26e-205 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEHPDDFL_00888 1.51e-138 - - - L - - - Resolvase, N terminal domain
NEHPDDFL_00889 1.82e-146 - - - L ko:K07497 - ko00000 hmm pf00665
NEHPDDFL_00890 4.67e-232 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
NEHPDDFL_00891 1.95e-220 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
NEHPDDFL_00892 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHPDDFL_00893 7.07e-106 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NEHPDDFL_00894 8.65e-81 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHPDDFL_00895 5.82e-124 tnpR1 - - L - - - Resolvase, N terminal domain
NEHPDDFL_00896 1.28e-74 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEHPDDFL_00897 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEHPDDFL_00898 7e-82 kdpE - - KT ko:K02483,ko:K07667 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NEHPDDFL_00899 1.71e-240 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
NEHPDDFL_00900 2.97e-234 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NEHPDDFL_00901 1.14e-143 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NEHPDDFL_00902 9.17e-126 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NEHPDDFL_00903 1.71e-241 - - - L - - - PFAM Integrase catalytic region
NEHPDDFL_00904 7.99e-225 - - - L - - - Transposase and inactivated derivatives, IS30 family
NEHPDDFL_00906 6.13e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
NEHPDDFL_00908 6.68e-57 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
NEHPDDFL_00909 5.94e-107 - - - - - - - -
NEHPDDFL_00910 4.44e-223 - - - L - - - Initiator Replication protein
NEHPDDFL_00911 1.15e-73 - - - - - - - -
NEHPDDFL_00912 2.27e-57 - - - - - - - -
NEHPDDFL_00913 4.53e-130 - - - S - - - Caspase domain
NEHPDDFL_00914 1.06e-64 - - - - - - - -
NEHPDDFL_00915 1.97e-05 - - - - - - - -
NEHPDDFL_00916 1.55e-174 - - - K - - - Helix-turn-helix domain
NEHPDDFL_00917 1.84e-19 - - - - - - - -
NEHPDDFL_00918 1.23e-81 - - - S - - - Protein of unknown function (DUF2992)
NEHPDDFL_00919 2.59e-77 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
NEHPDDFL_00920 1.11e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
NEHPDDFL_00921 5.09e-128 - - - L - - - Integrase
NEHPDDFL_00922 3.91e-82 - - - - - - - -
NEHPDDFL_00923 6.79e-16 - - - - - - - -
NEHPDDFL_00945 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NEHPDDFL_00946 3.28e-177 yhfI - - S - - - Metallo-beta-lactamase superfamily
NEHPDDFL_00947 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NEHPDDFL_00948 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NEHPDDFL_00949 4.93e-268 coiA - - S ko:K06198 - ko00000 Competence protein
NEHPDDFL_00950 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NEHPDDFL_00951 2.24e-148 yjbH - - Q - - - Thioredoxin
NEHPDDFL_00952 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NEHPDDFL_00953 1.29e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEHPDDFL_00954 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEHPDDFL_00955 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NEHPDDFL_00956 5.57e-247 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NEHPDDFL_00957 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
NEHPDDFL_00958 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
NEHPDDFL_00959 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEHPDDFL_00960 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NEHPDDFL_00962 2.95e-300 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEHPDDFL_00963 4.41e-59 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
NEHPDDFL_00964 7.16e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NEHPDDFL_00965 4.97e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEHPDDFL_00966 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NEHPDDFL_00967 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEHPDDFL_00968 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
NEHPDDFL_00969 1.35e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NEHPDDFL_00970 1.74e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEHPDDFL_00971 7.01e-76 ftsL - - D - - - Cell division protein FtsL
NEHPDDFL_00972 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NEHPDDFL_00973 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEHPDDFL_00974 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEHPDDFL_00975 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEHPDDFL_00976 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NEHPDDFL_00977 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NEHPDDFL_00978 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEHPDDFL_00979 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEHPDDFL_00980 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NEHPDDFL_00981 2.06e-187 ylmH - - S - - - S4 domain protein
NEHPDDFL_00982 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NEHPDDFL_00983 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEHPDDFL_00984 3.46e-242 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NEHPDDFL_00985 1.43e-124 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NEHPDDFL_00986 7.74e-47 - - - - - - - -
NEHPDDFL_00987 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEHPDDFL_00988 3.69e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NEHPDDFL_00989 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
NEHPDDFL_00990 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEHPDDFL_00991 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
NEHPDDFL_00992 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
NEHPDDFL_00993 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
NEHPDDFL_00994 1.22e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
NEHPDDFL_00995 0.0 - - - N - - - domain, Protein
NEHPDDFL_00996 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
NEHPDDFL_00997 1.02e-155 - - - S - - - repeat protein
NEHPDDFL_00998 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NEHPDDFL_00999 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEHPDDFL_01000 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NEHPDDFL_01001 2.16e-39 - - - - - - - -
NEHPDDFL_01002 2.43e-240 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NEHPDDFL_01003 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEHPDDFL_01004 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
NEHPDDFL_01005 6.45e-111 - - - - - - - -
NEHPDDFL_01006 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEHPDDFL_01007 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NEHPDDFL_01008 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NEHPDDFL_01009 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEHPDDFL_01010 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NEHPDDFL_01011 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
NEHPDDFL_01012 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
NEHPDDFL_01013 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NEHPDDFL_01014 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NEHPDDFL_01015 9.43e-259 - - - - - - - -
NEHPDDFL_01016 2.73e-134 - - - - - - - -
NEHPDDFL_01017 0.0 icaA - - M - - - Glycosyl transferase family group 2
NEHPDDFL_01018 0.0 - - - - - - - -
NEHPDDFL_01019 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NEHPDDFL_01020 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NEHPDDFL_01021 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NEHPDDFL_01022 4.98e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NEHPDDFL_01023 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEHPDDFL_01024 1.74e-250 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NEHPDDFL_01025 1.8e-162 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NEHPDDFL_01026 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NEHPDDFL_01027 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NEHPDDFL_01028 4.88e-239 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NEHPDDFL_01029 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NEHPDDFL_01030 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEHPDDFL_01031 4.48e-261 - - - EGP - - - Major Facilitator Superfamily
NEHPDDFL_01032 7.46e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEHPDDFL_01033 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEHPDDFL_01034 9.34e-201 - - - S - - - Tetratricopeptide repeat
NEHPDDFL_01035 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEHPDDFL_01036 3.21e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEHPDDFL_01037 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEHPDDFL_01038 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NEHPDDFL_01039 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
NEHPDDFL_01040 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
NEHPDDFL_01041 5.12e-31 - - - - - - - -
NEHPDDFL_01042 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NEHPDDFL_01043 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_01044 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEHPDDFL_01045 8.45e-162 epsB - - M - - - biosynthesis protein
NEHPDDFL_01046 2.02e-156 ywqD - - D - - - Capsular exopolysaccharide family
NEHPDDFL_01047 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NEHPDDFL_01048 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NEHPDDFL_01049 1.91e-163 tuaA - - M - - - Bacterial sugar transferase
NEHPDDFL_01050 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
NEHPDDFL_01051 1.94e-244 cps4G - - M - - - Glycosyltransferase Family 4
NEHPDDFL_01052 8.1e-299 - - - - - - - -
NEHPDDFL_01053 3.4e-228 cps4I - - M - - - Glycosyltransferase like family 2
NEHPDDFL_01054 0.0 cps4J - - S - - - MatE
NEHPDDFL_01055 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
NEHPDDFL_01056 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
NEHPDDFL_01057 4.24e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NEHPDDFL_01058 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
NEHPDDFL_01059 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEHPDDFL_01060 1.29e-59 - - - - - - - -
NEHPDDFL_01061 4.83e-227 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NEHPDDFL_01062 7.09e-180 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPDDFL_01063 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
NEHPDDFL_01064 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NEHPDDFL_01065 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEHPDDFL_01066 7.9e-136 - - - K - - - Helix-turn-helix domain
NEHPDDFL_01067 2.02e-270 - - - EGP - - - Major facilitator Superfamily
NEHPDDFL_01068 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
NEHPDDFL_01069 1.24e-184 - - - Q - - - Methyltransferase
NEHPDDFL_01070 1.75e-43 - - - - - - - -
NEHPDDFL_01071 1.1e-75 int3 - - L - - - Belongs to the 'phage' integrase family
NEHPDDFL_01072 4.78e-82 - - - T - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
NEHPDDFL_01077 4.16e-51 - - - S - - - Membrane
NEHPDDFL_01080 2.9e-24 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEHPDDFL_01082 3.68e-88 - - - S - - - DNA binding
NEHPDDFL_01092 1.12e-12 - - - - - - - -
NEHPDDFL_01095 5.18e-49 - - - L - - - Helix-turn-helix domain
NEHPDDFL_01096 4.04e-169 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NEHPDDFL_01098 1.62e-59 - - - - - - - -
NEHPDDFL_01099 3.77e-05 - - - - - - - -
NEHPDDFL_01100 1.96e-109 - - - S - - - methyltransferase activity
NEHPDDFL_01102 1.66e-40 - - - S - - - YopX protein
NEHPDDFL_01103 2.96e-15 - - - S - - - YopX protein
NEHPDDFL_01105 4.46e-27 - - - - - - - -
NEHPDDFL_01106 2.32e-86 - - - S - - - Transcriptional regulator, RinA family
NEHPDDFL_01107 1.7e-136 - - - V - - - HNH nucleases
NEHPDDFL_01108 3e-93 - - - L - - - Phage terminase small Subunit
NEHPDDFL_01109 0.0 - - - S - - - Phage Terminase
NEHPDDFL_01111 1.03e-261 - - - S - - - Phage portal protein
NEHPDDFL_01112 1.2e-138 - - - S - - - Caudovirus prohead serine protease
NEHPDDFL_01113 1.14e-120 - - - S ko:K06904 - ko00000 Phage capsid family
NEHPDDFL_01114 6.93e-53 - - - - - - - -
NEHPDDFL_01115 1.16e-74 - - - S - - - Phage head-tail joining protein
NEHPDDFL_01116 1.12e-86 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NEHPDDFL_01117 4.46e-66 - - - S - - - Protein of unknown function (DUF806)
NEHPDDFL_01118 3.14e-152 - - - S - - - Phage tail tube protein
NEHPDDFL_01119 1.71e-78 - - - S - - - Phage tail assembly chaperone proteins, TAC
NEHPDDFL_01120 0.0 - - - D - - - domain protein
NEHPDDFL_01121 9.72e-190 - - - S - - - Phage tail protein
NEHPDDFL_01122 5.11e-255 - - - S - - - Prophage endopeptidase tail
NEHPDDFL_01123 2.69e-62 - - - S - - - Phage minor structural protein
NEHPDDFL_01125 0.0 - - - S - - - Calcineurin-like phosphoesterase
NEHPDDFL_01126 7.53e-38 - - - - - - - -
NEHPDDFL_01127 7.02e-47 - - - - - - - -
NEHPDDFL_01129 3.77e-07 xhlB - - S - - - SPP1 phage holin
NEHPDDFL_01130 4.78e-228 - - - M - - - hydrolase, family 25
NEHPDDFL_01131 6.67e-58 - - - - - - - -
NEHPDDFL_01132 6.66e-57 - - - S - - - Bacteriophage holin
NEHPDDFL_01134 2.38e-294 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
NEHPDDFL_01135 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHPDDFL_01136 1.1e-183 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEHPDDFL_01137 1.89e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
NEHPDDFL_01138 6.27e-131 - - - L - - - Helix-turn-helix domain
NEHPDDFL_01139 6.58e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
NEHPDDFL_01140 3.81e-87 - - - - - - - -
NEHPDDFL_01141 1.01e-100 - - - - - - - -
NEHPDDFL_01142 6.62e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NEHPDDFL_01143 6.4e-122 - - - - - - - -
NEHPDDFL_01144 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEHPDDFL_01145 7.68e-48 ynzC - - S - - - UPF0291 protein
NEHPDDFL_01146 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
NEHPDDFL_01147 1.25e-154 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NEHPDDFL_01148 3.4e-177 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NEHPDDFL_01149 1.02e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NEHPDDFL_01150 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHPDDFL_01151 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
NEHPDDFL_01152 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NEHPDDFL_01153 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEHPDDFL_01154 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NEHPDDFL_01155 1.98e-112 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEHPDDFL_01156 3.71e-189 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEHPDDFL_01157 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NEHPDDFL_01158 9.37e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NEHPDDFL_01159 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEHPDDFL_01160 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEHPDDFL_01161 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NEHPDDFL_01162 3.82e-276 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NEHPDDFL_01163 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NEHPDDFL_01164 9.42e-63 ylxQ - - J - - - ribosomal protein
NEHPDDFL_01165 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEHPDDFL_01166 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEHPDDFL_01167 0.0 - - - G - - - Major Facilitator
NEHPDDFL_01168 5.21e-275 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEHPDDFL_01169 9.84e-123 - - - - - - - -
NEHPDDFL_01170 1.11e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEHPDDFL_01171 2.44e-245 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NEHPDDFL_01172 3.99e-112 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NEHPDDFL_01173 8.94e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEHPDDFL_01174 1.53e-241 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NEHPDDFL_01175 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NEHPDDFL_01176 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEHPDDFL_01177 4.52e-111 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEHPDDFL_01178 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NEHPDDFL_01179 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEHPDDFL_01180 8.49e-266 pbpX2 - - V - - - Beta-lactamase
NEHPDDFL_01181 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
NEHPDDFL_01182 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPDDFL_01183 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NEHPDDFL_01184 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPDDFL_01185 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NEHPDDFL_01186 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEHPDDFL_01187 1.73e-67 - - - - - - - -
NEHPDDFL_01188 4.78e-65 - - - - - - - -
NEHPDDFL_01189 1.06e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NEHPDDFL_01190 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NEHPDDFL_01191 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEHPDDFL_01192 2.56e-76 - - - - - - - -
NEHPDDFL_01193 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEHPDDFL_01194 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEHPDDFL_01195 1.35e-147 yjcF - - J - - - HAD-hyrolase-like
NEHPDDFL_01196 7.6e-213 - - - G - - - Fructosamine kinase
NEHPDDFL_01197 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
NEHPDDFL_01198 1.43e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NEHPDDFL_01199 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NEHPDDFL_01200 2.15e-131 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEHPDDFL_01201 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEHPDDFL_01202 1.84e-284 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHPDDFL_01203 1.42e-217 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NEHPDDFL_01204 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
NEHPDDFL_01205 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NEHPDDFL_01206 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NEHPDDFL_01207 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NEHPDDFL_01208 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NEHPDDFL_01209 6.33e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEHPDDFL_01210 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NEHPDDFL_01211 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEHPDDFL_01212 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NEHPDDFL_01213 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NEHPDDFL_01214 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NEHPDDFL_01215 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEHPDDFL_01216 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEHPDDFL_01217 1.18e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NEHPDDFL_01218 2.1e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_01219 1.56e-257 - - - - - - - -
NEHPDDFL_01220 5.21e-254 - - - - - - - -
NEHPDDFL_01221 2.11e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEHPDDFL_01222 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_01223 1.89e-63 - - - S - - - Psort location CytoplasmicMembrane, score
NEHPDDFL_01224 7.46e-40 - - - S - - - Psort location CytoplasmicMembrane, score
NEHPDDFL_01225 9.55e-95 - - - K - - - MarR family
NEHPDDFL_01226 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEHPDDFL_01228 3.43e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_01229 7.05e-172 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NEHPDDFL_01230 1.91e-261 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEHPDDFL_01231 1.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
NEHPDDFL_01232 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEHPDDFL_01234 7.96e-223 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
NEHPDDFL_01235 5.72e-207 - - - K - - - Transcriptional regulator
NEHPDDFL_01236 2.12e-102 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
NEHPDDFL_01237 5.05e-146 - - - GM - - - NmrA-like family
NEHPDDFL_01238 3.9e-208 - - - S - - - Alpha beta hydrolase
NEHPDDFL_01239 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
NEHPDDFL_01240 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NEHPDDFL_01241 7.51e-147 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
NEHPDDFL_01242 6.03e-36 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_01243 4.05e-90 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHPDDFL_01245 2.15e-07 - - - K - - - transcriptional regulator
NEHPDDFL_01246 3.08e-271 - - - S - - - membrane
NEHPDDFL_01247 6.13e-105 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_01248 0.0 - - - S - - - Zinc finger, swim domain protein
NEHPDDFL_01249 8.09e-146 - - - GM - - - epimerase
NEHPDDFL_01250 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
NEHPDDFL_01251 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
NEHPDDFL_01252 5.1e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
NEHPDDFL_01253 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NEHPDDFL_01254 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEHPDDFL_01255 1.12e-265 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NEHPDDFL_01256 4.38e-102 - - - K - - - Transcriptional regulator
NEHPDDFL_01257 1.54e-305 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
NEHPDDFL_01258 1.09e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEHPDDFL_01259 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
NEHPDDFL_01260 1.51e-232 - - - C - - - Zinc-binding dehydrogenase
NEHPDDFL_01261 6.09e-281 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
NEHPDDFL_01262 5.78e-268 - - - - - - - -
NEHPDDFL_01263 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEHPDDFL_01264 1.94e-83 - - - P - - - Rhodanese Homology Domain
NEHPDDFL_01265 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NEHPDDFL_01266 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEHPDDFL_01267 3.85e-209 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_01268 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NEHPDDFL_01269 3.38e-293 - - - M - - - O-Antigen ligase
NEHPDDFL_01270 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NEHPDDFL_01271 1.61e-251 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NEHPDDFL_01272 3.17e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NEHPDDFL_01273 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEHPDDFL_01274 2.02e-39 - - - S - - - Protein of unknown function (DUF2929)
NEHPDDFL_01275 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NEHPDDFL_01276 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NEHPDDFL_01277 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NEHPDDFL_01278 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
NEHPDDFL_01279 1.6e-217 yitL - - S ko:K00243 - ko00000 S1 domain
NEHPDDFL_01280 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NEHPDDFL_01281 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHPDDFL_01282 5.83e-175 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEHPDDFL_01283 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEHPDDFL_01284 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NEHPDDFL_01285 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEHPDDFL_01286 3.38e-252 - - - S - - - Helix-turn-helix domain
NEHPDDFL_01287 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEHPDDFL_01288 5.45e-38 - - - M - - - Lysin motif
NEHPDDFL_01289 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NEHPDDFL_01290 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NEHPDDFL_01291 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NEHPDDFL_01292 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEHPDDFL_01293 5.83e-291 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NEHPDDFL_01294 1.29e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NEHPDDFL_01295 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEHPDDFL_01296 3.65e-291 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NEHPDDFL_01297 6.46e-109 - - - - - - - -
NEHPDDFL_01298 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_01299 4.04e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEHPDDFL_01300 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NEHPDDFL_01301 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
NEHPDDFL_01302 5.91e-209 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
NEHPDDFL_01303 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NEHPDDFL_01304 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
NEHPDDFL_01305 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NEHPDDFL_01306 0.0 qacA - - EGP - - - Major Facilitator
NEHPDDFL_01307 2.48e-252 XK27_00915 - - C - - - Luciferase-like monooxygenase
NEHPDDFL_01308 1.75e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NEHPDDFL_01309 1.27e-222 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
NEHPDDFL_01310 1.22e-219 cpsY - - K - - - Transcriptional regulator, LysR family
NEHPDDFL_01311 5.13e-292 XK27_05470 - - E - - - Methionine synthase
NEHPDDFL_01312 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NEHPDDFL_01313 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEHPDDFL_01314 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NEHPDDFL_01315 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEHPDDFL_01316 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NEHPDDFL_01317 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
NEHPDDFL_01318 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NEHPDDFL_01319 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NEHPDDFL_01320 7.34e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NEHPDDFL_01321 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NEHPDDFL_01322 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEHPDDFL_01323 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEHPDDFL_01324 3.82e-228 - - - K - - - Transcriptional regulator
NEHPDDFL_01325 3.91e-216 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NEHPDDFL_01326 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NEHPDDFL_01327 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEHPDDFL_01328 1.07e-43 - - - S - - - YozE SAM-like fold
NEHPDDFL_01329 3.59e-204 - - - L - - - Phage integrase, N-terminal SAM-like domain
NEHPDDFL_01330 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEHPDDFL_01331 1.06e-313 - - - M - - - Glycosyl transferase family group 2
NEHPDDFL_01332 7.59e-86 - - - - - - - -
NEHPDDFL_01333 0.0 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
NEHPDDFL_01334 1.48e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEHPDDFL_01335 4.87e-123 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NEHPDDFL_01336 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHPDDFL_01337 8.63e-275 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHPDDFL_01338 6.51e-247 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NEHPDDFL_01339 2.13e-151 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NEHPDDFL_01340 3.35e-290 - - - - - - - -
NEHPDDFL_01341 2.49e-245 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NEHPDDFL_01342 4.64e-88 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NEHPDDFL_01343 7.79e-78 - - - - - - - -
NEHPDDFL_01344 1.3e-174 - - - - - - - -
NEHPDDFL_01345 4.31e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NEHPDDFL_01346 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
NEHPDDFL_01347 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
NEHPDDFL_01348 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
NEHPDDFL_01350 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
NEHPDDFL_01351 4.87e-191 - - - C - - - Domain of unknown function (DUF4931)
NEHPDDFL_01352 2.37e-65 - - - - - - - -
NEHPDDFL_01353 3.15e-29 - - - - - - - -
NEHPDDFL_01354 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
NEHPDDFL_01355 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
NEHPDDFL_01356 1.11e-205 - - - S - - - EDD domain protein, DegV family
NEHPDDFL_01357 1.97e-87 - - - K - - - Transcriptional regulator
NEHPDDFL_01358 0.0 FbpA - - K - - - Fibronectin-binding protein
NEHPDDFL_01359 9.28e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEHPDDFL_01360 5.3e-209 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_01361 1.37e-119 - - - F - - - NUDIX domain
NEHPDDFL_01362 1.19e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
NEHPDDFL_01363 8.49e-92 - - - S - - - LuxR family transcriptional regulator
NEHPDDFL_01364 1.92e-168 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
NEHPDDFL_01366 1.9e-93 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NEHPDDFL_01367 2.01e-145 - - - G - - - Phosphoglycerate mutase family
NEHPDDFL_01368 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NEHPDDFL_01369 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NEHPDDFL_01370 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEHPDDFL_01371 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEHPDDFL_01372 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEHPDDFL_01373 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NEHPDDFL_01374 5.89e-81 esbA - - S - - - Family of unknown function (DUF5322)
NEHPDDFL_01375 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NEHPDDFL_01376 2.44e-267 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
NEHPDDFL_01377 3.69e-187 - - - S - - - hydrolase activity, acting on ester bonds
NEHPDDFL_01378 6.79e-249 - - - - - - - -
NEHPDDFL_01379 1.9e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEHPDDFL_01380 5.46e-157 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NEHPDDFL_01381 8.41e-97 XK27_05710 - - K - - - Acetyltransferase (GNAT) domain
NEHPDDFL_01382 4.81e-233 - - - V - - - LD-carboxypeptidase
NEHPDDFL_01383 2.13e-312 - - - M ko:K07273 - ko00000 hydrolase, family 25
NEHPDDFL_01384 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
NEHPDDFL_01385 3.46e-267 mccF - - V - - - LD-carboxypeptidase
NEHPDDFL_01386 1.67e-307 - - - M - - - Glycosyltransferase, group 2 family protein
NEHPDDFL_01387 7.86e-96 - - - S - - - SnoaL-like domain
NEHPDDFL_01388 1.7e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NEHPDDFL_01389 4.26e-307 - - - P - - - Major Facilitator Superfamily
NEHPDDFL_01390 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPDDFL_01391 4.11e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NEHPDDFL_01393 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NEHPDDFL_01394 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
NEHPDDFL_01395 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NEHPDDFL_01396 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NEHPDDFL_01397 1.97e-229 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NEHPDDFL_01398 1.63e-233 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEHPDDFL_01399 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHPDDFL_01400 4.95e-35 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHPDDFL_01401 4.38e-108 - - - T - - - Universal stress protein family
NEHPDDFL_01402 3.19e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NEHPDDFL_01403 1.41e-141 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_01404 2.32e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEHPDDFL_01405 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
NEHPDDFL_01406 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NEHPDDFL_01407 2.55e-288 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NEHPDDFL_01408 2.53e-107 ypmB - - S - - - protein conserved in bacteria
NEHPDDFL_01409 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NEHPDDFL_01410 1.72e-216 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NEHPDDFL_01411 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NEHPDDFL_01412 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NEHPDDFL_01413 1.43e-249 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NEHPDDFL_01414 6.77e-247 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NEHPDDFL_01415 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NEHPDDFL_01416 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NEHPDDFL_01417 2.06e-158 - - - S - - - Domain of unknown function (DUF4767)
NEHPDDFL_01418 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NEHPDDFL_01419 2.23e-191 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NEHPDDFL_01420 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NEHPDDFL_01421 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEHPDDFL_01422 3.23e-58 - - - - - - - -
NEHPDDFL_01423 1.25e-66 - - - - - - - -
NEHPDDFL_01424 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
NEHPDDFL_01425 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
NEHPDDFL_01426 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEHPDDFL_01427 8.39e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NEHPDDFL_01428 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEHPDDFL_01429 1.06e-53 - - - - - - - -
NEHPDDFL_01430 4e-40 - - - S - - - CsbD-like
NEHPDDFL_01431 2.22e-55 - - - S - - - transglycosylase associated protein
NEHPDDFL_01432 5.79e-21 - - - - - - - -
NEHPDDFL_01433 1.51e-48 - - - - - - - -
NEHPDDFL_01434 1.47e-210 - - - I - - - Diacylglycerol kinase catalytic domain
NEHPDDFL_01435 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
NEHPDDFL_01436 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
NEHPDDFL_01437 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
NEHPDDFL_01438 2.05e-55 - - - - - - - -
NEHPDDFL_01439 1.57e-64 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
NEHPDDFL_01440 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
NEHPDDFL_01441 4.83e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NEHPDDFL_01442 2.02e-39 - - - - - - - -
NEHPDDFL_01443 4.97e-70 - - - - - - - -
NEHPDDFL_01445 1.19e-13 - - - - - - - -
NEHPDDFL_01448 7.7e-84 - - - L - - - Phage integrase, N-terminal SAM-like domain
NEHPDDFL_01449 1.14e-193 - - - O - - - Band 7 protein
NEHPDDFL_01450 0.0 - - - EGP - - - Major Facilitator
NEHPDDFL_01451 1.49e-121 - - - K - - - transcriptional regulator
NEHPDDFL_01452 8.88e-246 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEHPDDFL_01453 4.94e-114 ykhA - - I - - - Thioesterase superfamily
NEHPDDFL_01454 3.73e-207 - - - K - - - LysR substrate binding domain
NEHPDDFL_01455 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NEHPDDFL_01456 1.75e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NEHPDDFL_01457 1.88e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NEHPDDFL_01458 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NEHPDDFL_01459 6.43e-203 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEHPDDFL_01460 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NEHPDDFL_01461 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NEHPDDFL_01462 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEHPDDFL_01463 1.54e-289 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEHPDDFL_01464 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NEHPDDFL_01465 2.97e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NEHPDDFL_01466 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEHPDDFL_01467 9.77e-231 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEHPDDFL_01468 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NEHPDDFL_01469 1.33e-228 yneE - - K - - - Transcriptional regulator
NEHPDDFL_01470 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPDDFL_01471 2.2e-79 - - - S - - - Protein of unknown function (DUF1648)
NEHPDDFL_01472 8.04e-254 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NEHPDDFL_01473 3.53e-227 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
NEHPDDFL_01474 1.69e-125 entB - - Q - - - Isochorismatase family
NEHPDDFL_01475 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEHPDDFL_01476 1.04e-286 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEHPDDFL_01477 6.14e-140 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NEHPDDFL_01478 2.69e-162 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NEHPDDFL_01479 2.45e-225 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEHPDDFL_01480 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
NEHPDDFL_01481 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
NEHPDDFL_01482 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
NEHPDDFL_01483 1.18e-178 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NEHPDDFL_01484 1.1e-112 - - - - - - - -
NEHPDDFL_01485 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEHPDDFL_01486 1.03e-66 - - - - - - - -
NEHPDDFL_01487 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEHPDDFL_01488 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NEHPDDFL_01489 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEHPDDFL_01490 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NEHPDDFL_01491 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NEHPDDFL_01492 9.38e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEHPDDFL_01493 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NEHPDDFL_01494 7.71e-298 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEHPDDFL_01495 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NEHPDDFL_01496 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEHPDDFL_01497 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEHPDDFL_01498 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NEHPDDFL_01499 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NEHPDDFL_01500 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NEHPDDFL_01501 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
NEHPDDFL_01502 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NEHPDDFL_01503 4.92e-84 - - - S - - - Protein of unknown function (DUF1093)
NEHPDDFL_01504 4.83e-31 - - - K - - - helix_turn_helix, mercury resistance
NEHPDDFL_01505 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NEHPDDFL_01506 5.15e-16 - - - - - - - -
NEHPDDFL_01507 5.71e-83 - - - - - - - -
NEHPDDFL_01508 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_01509 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_01510 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
NEHPDDFL_01511 7.45e-15 - - - S - - - FRG
NEHPDDFL_01512 3.77e-278 - - - EGP - - - Major Facilitator
NEHPDDFL_01513 1.62e-150 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHPDDFL_01514 3.04e-260 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
NEHPDDFL_01515 7.15e-183 - - - L - - - COG3547 Transposase and inactivated derivatives
NEHPDDFL_01527 5.4e-118 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
NEHPDDFL_01528 5.46e-238 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
NEHPDDFL_01529 1.25e-124 - - - - - - - -
NEHPDDFL_01530 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
NEHPDDFL_01531 1.46e-200 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NEHPDDFL_01532 8.77e-37 - - - L - - - Psort location Cytoplasmic, score
NEHPDDFL_01533 3.11e-52 - - - L - - - Psort location Cytoplasmic, score
NEHPDDFL_01534 1.51e-82 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NEHPDDFL_01535 0.0 - - - L - - - MobA MobL family protein
NEHPDDFL_01536 1.69e-37 - - - - - - - -
NEHPDDFL_01537 8.26e-54 - - - - - - - -
NEHPDDFL_01538 0.0 eriC - - P ko:K03281 - ko00000 chloride
NEHPDDFL_01539 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
NEHPDDFL_01540 5.83e-182 - - - L - - - COG3547 Transposase and inactivated derivatives
NEHPDDFL_01541 7.81e-247 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEHPDDFL_01542 7e-208 - - - L ko:K07497 - ko00000 hmm pf00665
NEHPDDFL_01543 2.22e-169 - - - L - - - Helix-turn-helix domain
NEHPDDFL_01544 3.36e-199 - - - G - - - Peptidase_C39 like family
NEHPDDFL_01545 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEHPDDFL_01546 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
NEHPDDFL_01547 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
NEHPDDFL_01548 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
NEHPDDFL_01549 0.0 levR - - K - - - Sigma-54 interaction domain
NEHPDDFL_01550 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NEHPDDFL_01551 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
NEHPDDFL_01552 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEHPDDFL_01553 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
NEHPDDFL_01554 2.83e-316 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
NEHPDDFL_01555 6.33e-185 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEHPDDFL_01556 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
NEHPDDFL_01557 2.29e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEHPDDFL_01558 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
NEHPDDFL_01559 6.04e-227 - - - EG - - - EamA-like transporter family
NEHPDDFL_01560 3.3e-166 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEHPDDFL_01561 1.12e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
NEHPDDFL_01562 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NEHPDDFL_01563 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NEHPDDFL_01564 2.43e-68 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NEHPDDFL_01565 3.29e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NEHPDDFL_01566 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEHPDDFL_01567 8.13e-264 yacL - - S - - - domain protein
NEHPDDFL_01568 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEHPDDFL_01569 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEHPDDFL_01570 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NEHPDDFL_01571 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEHPDDFL_01572 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
NEHPDDFL_01573 1.12e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
NEHPDDFL_01574 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NEHPDDFL_01575 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEHPDDFL_01576 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NEHPDDFL_01577 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHPDDFL_01578 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEHPDDFL_01579 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEHPDDFL_01580 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEHPDDFL_01581 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEHPDDFL_01582 1.5e-228 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NEHPDDFL_01583 1.84e-83 - - - L - - - nuclease
NEHPDDFL_01584 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEHPDDFL_01585 2.37e-140 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NEHPDDFL_01586 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHPDDFL_01587 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHPDDFL_01588 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NEHPDDFL_01589 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NEHPDDFL_01590 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEHPDDFL_01591 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEHPDDFL_01592 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NEHPDDFL_01593 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEHPDDFL_01594 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
NEHPDDFL_01595 3.33e-298 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHPDDFL_01596 4.97e-67 - 2.7.1.194 - G ko:K02821,ko:K03483 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHPDDFL_01597 2.27e-54 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEHPDDFL_01598 4.67e-280 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
NEHPDDFL_01599 1.16e-128 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
NEHPDDFL_01600 1.28e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEHPDDFL_01601 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
NEHPDDFL_01602 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NEHPDDFL_01603 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
NEHPDDFL_01604 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEHPDDFL_01605 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NEHPDDFL_01606 4.95e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NEHPDDFL_01607 5.35e-270 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
NEHPDDFL_01608 1.14e-186 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
NEHPDDFL_01609 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_01610 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
NEHPDDFL_01611 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NEHPDDFL_01612 2.84e-241 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
NEHPDDFL_01613 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NEHPDDFL_01614 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NEHPDDFL_01615 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NEHPDDFL_01616 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEHPDDFL_01617 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NEHPDDFL_01618 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NEHPDDFL_01619 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_01620 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEHPDDFL_01621 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEHPDDFL_01622 0.0 ydaO - - E - - - amino acid
NEHPDDFL_01623 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
NEHPDDFL_01624 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NEHPDDFL_01625 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NEHPDDFL_01626 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NEHPDDFL_01627 6.92e-163 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NEHPDDFL_01628 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEHPDDFL_01629 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEHPDDFL_01630 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEHPDDFL_01631 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
NEHPDDFL_01632 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NEHPDDFL_01633 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEHPDDFL_01634 6.91e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NEHPDDFL_01635 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NEHPDDFL_01636 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NEHPDDFL_01637 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEHPDDFL_01638 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEHPDDFL_01639 8.96e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NEHPDDFL_01640 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
NEHPDDFL_01641 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NEHPDDFL_01642 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NEHPDDFL_01643 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEHPDDFL_01644 1.15e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NEHPDDFL_01645 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NEHPDDFL_01646 3.69e-159 - - - T - - - Putative diguanylate phosphodiesterase
NEHPDDFL_01647 0.0 nox - - C - - - NADH oxidase
NEHPDDFL_01648 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEHPDDFL_01649 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
NEHPDDFL_01650 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
NEHPDDFL_01651 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NEHPDDFL_01652 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
NEHPDDFL_01653 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEHPDDFL_01654 6.33e-133 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NEHPDDFL_01655 4.38e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
NEHPDDFL_01656 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NEHPDDFL_01657 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEHPDDFL_01658 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEHPDDFL_01659 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEHPDDFL_01660 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEHPDDFL_01661 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NEHPDDFL_01662 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
NEHPDDFL_01663 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NEHPDDFL_01664 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NEHPDDFL_01665 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NEHPDDFL_01666 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
NEHPDDFL_01667 1.55e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHPDDFL_01668 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEHPDDFL_01670 1.14e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
NEHPDDFL_01671 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
NEHPDDFL_01672 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEHPDDFL_01673 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NEHPDDFL_01674 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEHPDDFL_01675 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEHPDDFL_01676 5.11e-171 - - - - - - - -
NEHPDDFL_01677 0.0 eriC - - P ko:K03281 - ko00000 chloride
NEHPDDFL_01678 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NEHPDDFL_01679 1.1e-178 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
NEHPDDFL_01680 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NEHPDDFL_01681 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEHPDDFL_01682 0.0 - - - M - - - Domain of unknown function (DUF5011)
NEHPDDFL_01683 0.0 - - - M - - - Domain of unknown function (DUF5011)
NEHPDDFL_01684 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_01685 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_01686 5.62e-137 - - - - - - - -
NEHPDDFL_01687 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEHPDDFL_01688 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEHPDDFL_01689 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NEHPDDFL_01690 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NEHPDDFL_01691 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
NEHPDDFL_01692 7.18e-131 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NEHPDDFL_01693 2.53e-198 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NEHPDDFL_01694 3.09e-213 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
NEHPDDFL_01695 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NEHPDDFL_01696 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
NEHPDDFL_01697 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEHPDDFL_01698 6.9e-157 - - - S - - - Protein of unknown function (DUF1361)
NEHPDDFL_01699 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEHPDDFL_01700 2.18e-182 ybbR - - S - - - YbbR-like protein
NEHPDDFL_01701 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEHPDDFL_01702 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEHPDDFL_01703 5.44e-159 - - - T - - - EAL domain
NEHPDDFL_01704 8.04e-190 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
NEHPDDFL_01705 1.21e-135 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_01706 2.07e-263 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NEHPDDFL_01707 3.38e-70 - - - - - - - -
NEHPDDFL_01708 2.49e-95 - - - - - - - -
NEHPDDFL_01709 7.06e-169 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NEHPDDFL_01710 1.73e-178 - - - EGP - - - Transmembrane secretion effector
NEHPDDFL_01711 2.09e-42 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
NEHPDDFL_01712 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEHPDDFL_01713 5.03e-183 - - - - - - - -
NEHPDDFL_01715 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
NEHPDDFL_01716 5.51e-46 - - - - - - - -
NEHPDDFL_01717 2.08e-117 - - - V - - - VanZ like family
NEHPDDFL_01718 1.06e-314 - - - EGP - - - Major Facilitator
NEHPDDFL_01719 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NEHPDDFL_01720 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NEHPDDFL_01721 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NEHPDDFL_01722 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
NEHPDDFL_01723 6.16e-107 - - - K - - - Transcriptional regulator
NEHPDDFL_01724 1.36e-27 - - - - - - - -
NEHPDDFL_01725 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NEHPDDFL_01726 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEHPDDFL_01727 3.3e-199 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NEHPDDFL_01728 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEHPDDFL_01729 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEHPDDFL_01730 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEHPDDFL_01731 0.0 oatA - - I - - - Acyltransferase
NEHPDDFL_01732 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NEHPDDFL_01733 1.89e-90 - - - O - - - OsmC-like protein
NEHPDDFL_01734 1.21e-63 - - - - - - - -
NEHPDDFL_01735 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
NEHPDDFL_01736 6.12e-115 - - - - - - - -
NEHPDDFL_01737 3.03e-190 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
NEHPDDFL_01738 7.48e-96 - - - F - - - Nudix hydrolase
NEHPDDFL_01739 1.48e-27 - - - - - - - -
NEHPDDFL_01740 2.01e-133 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
NEHPDDFL_01741 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NEHPDDFL_01742 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NEHPDDFL_01743 1.01e-188 - - - - - - - -
NEHPDDFL_01745 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
NEHPDDFL_01746 3.21e-268 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEHPDDFL_01747 1.46e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHPDDFL_01748 5.2e-54 - - - - - - - -
NEHPDDFL_01750 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_01751 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NEHPDDFL_01752 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_01753 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_01754 1.22e-108 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEHPDDFL_01755 4.68e-198 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
NEHPDDFL_01756 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEHPDDFL_01757 4.31e-180 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
NEHPDDFL_01758 0.0 steT - - E ko:K03294 - ko00000 amino acid
NEHPDDFL_01759 6.78e-56 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NEHPDDFL_01760 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
NEHPDDFL_01761 3.08e-93 - - - K - - - MarR family
NEHPDDFL_01762 2.27e-269 - - - EGP - - - Major Facilitator Superfamily
NEHPDDFL_01763 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
NEHPDDFL_01764 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_01765 2.42e-299 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEHPDDFL_01766 1.13e-102 rppH3 - - F - - - NUDIX domain
NEHPDDFL_01767 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
NEHPDDFL_01768 1.61e-36 - - - - - - - -
NEHPDDFL_01769 2.61e-163 pgm3 - - G - - - Phosphoglycerate mutase family
NEHPDDFL_01770 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
NEHPDDFL_01771 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NEHPDDFL_01772 3.27e-224 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NEHPDDFL_01773 2.72e-144 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NEHPDDFL_01774 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NEHPDDFL_01775 3.59e-212 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
NEHPDDFL_01776 3.69e-230 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NEHPDDFL_01777 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NEHPDDFL_01778 1.08e-71 - - - - - - - -
NEHPDDFL_01779 1.37e-83 - - - K - - - Helix-turn-helix domain
NEHPDDFL_01780 0.0 - - - L - - - AAA domain
NEHPDDFL_01781 2.01e-149 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_01782 1.85e-75 - - - K - - - HxlR-like helix-turn-helix
NEHPDDFL_01783 4.73e-302 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
NEHPDDFL_01784 0.0 - - - S - - - Cysteine-rich secretory protein family
NEHPDDFL_01785 3.61e-61 - - - S - - - MORN repeat
NEHPDDFL_01786 0.0 XK27_09800 - - I - - - Acyltransferase family
NEHPDDFL_01787 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
NEHPDDFL_01788 1.95e-116 - - - - - - - -
NEHPDDFL_01789 5.74e-32 - - - - - - - -
NEHPDDFL_01790 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
NEHPDDFL_01791 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
NEHPDDFL_01792 1.22e-193 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
NEHPDDFL_01793 1.54e-217 yjdB - - S - - - Domain of unknown function (DUF4767)
NEHPDDFL_01794 2.3e-65 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEHPDDFL_01795 1.22e-137 - - - G - - - Glycogen debranching enzyme
NEHPDDFL_01796 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NEHPDDFL_01797 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NEHPDDFL_01798 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
NEHPDDFL_01799 1.68e-111 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NEHPDDFL_01800 8.31e-225 - - - L - - - Belongs to the 'phage' integrase family
NEHPDDFL_01801 3.7e-61 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NEHPDDFL_01802 1.83e-123 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
NEHPDDFL_01803 0.0 - - - M - - - MucBP domain
NEHPDDFL_01804 1.42e-08 - - - - - - - -
NEHPDDFL_01805 8.92e-116 - - - S - - - AAA domain
NEHPDDFL_01806 1.83e-180 - - - K - - - sequence-specific DNA binding
NEHPDDFL_01807 6.57e-125 - - - K - - - Helix-turn-helix domain
NEHPDDFL_01808 1.13e-219 - - - K - - - Transcriptional regulator
NEHPDDFL_01809 0.0 - - - C - - - FMN_bind
NEHPDDFL_01811 3.54e-105 - - - K - - - Transcriptional regulator
NEHPDDFL_01812 1.41e-150 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NEHPDDFL_01813 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NEHPDDFL_01814 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NEHPDDFL_01815 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NEHPDDFL_01816 4.42e-289 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NEHPDDFL_01817 9.05e-55 - - - - - - - -
NEHPDDFL_01818 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
NEHPDDFL_01819 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEHPDDFL_01820 1.72e-211 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEHPDDFL_01821 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPDDFL_01822 8.34e-179 - - - S - - - NADPH-dependent FMN reductase
NEHPDDFL_01823 3.91e-244 - - - - - - - -
NEHPDDFL_01824 2.41e-280 yibE - - S - - - overlaps another CDS with the same product name
NEHPDDFL_01825 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
NEHPDDFL_01826 1.22e-132 - - - K - - - FR47-like protein
NEHPDDFL_01827 1.5e-156 gpm5 - - G - - - Phosphoglycerate mutase family
NEHPDDFL_01828 3.33e-64 - - - - - - - -
NEHPDDFL_01829 7.32e-247 - - - I - - - alpha/beta hydrolase fold
NEHPDDFL_01830 0.0 xylP2 - - G - - - symporter
NEHPDDFL_01831 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEHPDDFL_01832 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
NEHPDDFL_01833 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NEHPDDFL_01834 8.09e-65 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NEHPDDFL_01835 1.43e-155 azlC - - E - - - branched-chain amino acid
NEHPDDFL_01836 1.75e-47 - - - K - - - MerR HTH family regulatory protein
NEHPDDFL_01837 5.92e-170 - - - - - - - -
NEHPDDFL_01838 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
NEHPDDFL_01839 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NEHPDDFL_01840 7.79e-112 - - - K - - - MerR HTH family regulatory protein
NEHPDDFL_01841 1.36e-77 - - - - - - - -
NEHPDDFL_01842 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
NEHPDDFL_01843 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NEHPDDFL_01844 4.6e-169 - - - S - - - Putative threonine/serine exporter
NEHPDDFL_01845 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
NEHPDDFL_01846 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NEHPDDFL_01847 3.41e-152 - - - I - - - phosphatase
NEHPDDFL_01848 3.88e-198 - - - I - - - alpha/beta hydrolase fold
NEHPDDFL_01849 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEHPDDFL_01850 1.7e-118 - - - K - - - Transcriptional regulator
NEHPDDFL_01851 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NEHPDDFL_01852 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NEHPDDFL_01853 1.29e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NEHPDDFL_01854 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
NEHPDDFL_01855 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEHPDDFL_01863 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NEHPDDFL_01864 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEHPDDFL_01865 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_01866 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHPDDFL_01867 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHPDDFL_01868 1.81e-150 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
NEHPDDFL_01869 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEHPDDFL_01870 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEHPDDFL_01871 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEHPDDFL_01872 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NEHPDDFL_01873 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEHPDDFL_01874 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NEHPDDFL_01875 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEHPDDFL_01876 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEHPDDFL_01877 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEHPDDFL_01878 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEHPDDFL_01879 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEHPDDFL_01880 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEHPDDFL_01881 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NEHPDDFL_01882 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEHPDDFL_01883 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEHPDDFL_01884 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEHPDDFL_01885 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEHPDDFL_01886 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEHPDDFL_01887 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEHPDDFL_01888 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEHPDDFL_01889 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEHPDDFL_01890 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NEHPDDFL_01891 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NEHPDDFL_01892 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEHPDDFL_01893 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEHPDDFL_01894 9.87e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEHPDDFL_01895 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEHPDDFL_01896 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEHPDDFL_01897 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHPDDFL_01898 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NEHPDDFL_01899 2.94e-282 B4168_4126 - - L ko:K07493 - ko00000 Transposase
NEHPDDFL_01901 1.28e-98 - - - L - - - Transposase DDE domain
NEHPDDFL_01902 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
NEHPDDFL_01903 7.74e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NEHPDDFL_01904 1.33e-77 - - - - - - - -
NEHPDDFL_01905 5.37e-182 - - - - - - - -
NEHPDDFL_01906 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NEHPDDFL_01907 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_01908 6.32e-86 yxeA - - S - - - Protein of unknown function (DUF1093)
NEHPDDFL_01909 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
NEHPDDFL_01911 1e-80 - - - K - - - IrrE N-terminal-like domain
NEHPDDFL_01913 2.93e-73 - - - V - - - Abortive infection bacteriophage resistance protein
NEHPDDFL_01914 9.99e-58 - - - S - - - Bacteriophage holin
NEHPDDFL_01915 4.55e-64 - - - - - - - -
NEHPDDFL_01916 1.49e-230 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEHPDDFL_01918 8.44e-91 - - - S - - - Protein of unknown function (DUF1617)
NEHPDDFL_01919 0.0 - - - LM - - - DNA recombination
NEHPDDFL_01920 2.29e-81 - - - - - - - -
NEHPDDFL_01921 0.0 - - - D - - - domain protein
NEHPDDFL_01922 3.76e-32 - - - - - - - -
NEHPDDFL_01923 4.97e-84 - - - - - - - -
NEHPDDFL_01924 7.42e-102 - - - S - - - Phage tail tube protein, TTP
NEHPDDFL_01925 5.8e-71 - - - - - - - -
NEHPDDFL_01926 9.24e-116 - - - - - - - -
NEHPDDFL_01927 1.55e-67 - - - - - - - -
NEHPDDFL_01928 2.39e-67 - - - - - - - -
NEHPDDFL_01930 2.08e-222 - - - S - - - Phage major capsid protein E
NEHPDDFL_01931 5.72e-64 - - - - - - - -
NEHPDDFL_01934 3.05e-41 - - - - - - - -
NEHPDDFL_01935 0.0 - - - S - - - Phage Mu protein F like protein
NEHPDDFL_01936 4.98e-51 - - - J ko:K07584 - ko00000 Cysteine protease Prp
NEHPDDFL_01937 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
NEHPDDFL_01938 4.38e-306 - - - S - - - Terminase-like family
NEHPDDFL_01939 3.96e-81 - - - L ko:K07474 - ko00000 Terminase small subunit
NEHPDDFL_01941 2.39e-26 - - - - - - - -
NEHPDDFL_01946 3.86e-107 - - - S - - - Phage transcriptional regulator, ArpU family
NEHPDDFL_01947 7.43e-26 - - - - - - - -
NEHPDDFL_01948 5.69e-46 - - - - - - - -
NEHPDDFL_01950 2.2e-106 - - - S - - - methyltransferase activity
NEHPDDFL_01951 6.51e-06 - - - - - - - -
NEHPDDFL_01952 3.31e-37 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEHPDDFL_01953 8.89e-20 - - - S - - - YjzC-like protein
NEHPDDFL_01955 5.9e-84 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NEHPDDFL_01956 4.51e-81 - - - - - - - -
NEHPDDFL_01957 8.97e-65 - - - - - - - -
NEHPDDFL_01958 3.84e-193 - - - L - - - DnaD domain protein
NEHPDDFL_01959 1.04e-76 - - - - - - - -
NEHPDDFL_01960 1.14e-69 - - - S - - - Bacteriophage Mu Gam like protein
NEHPDDFL_01963 2.12e-101 - - - - - - - -
NEHPDDFL_01964 1.28e-69 - - - - - - - -
NEHPDDFL_01967 2.31e-09 - - - K - - - Transcriptional regulator, XRE family
NEHPDDFL_01968 1.19e-24 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEHPDDFL_01973 4.65e-52 - - - K - - - Helix-turn-helix domain
NEHPDDFL_01974 9.47e-94 - - - E - - - IrrE N-terminal-like domain
NEHPDDFL_01975 7.9e-74 - - - - - - - -
NEHPDDFL_01978 3e-66 - - - - - - - -
NEHPDDFL_01982 8.61e-15 - - - - - - - -
NEHPDDFL_01984 1.62e-279 int3 - - L - - - Belongs to the 'phage' integrase family
NEHPDDFL_01986 1.98e-40 - - - - - - - -
NEHPDDFL_01988 1.28e-51 - - - - - - - -
NEHPDDFL_01989 9.28e-58 - - - - - - - -
NEHPDDFL_01990 1.27e-109 - - - K - - - MarR family
NEHPDDFL_01991 0.0 - - - D - - - nuclear chromosome segregation
NEHPDDFL_01992 0.0 inlJ - - M - - - MucBP domain
NEHPDDFL_01993 6.58e-24 - - - - - - - -
NEHPDDFL_01994 3.26e-24 - - - - - - - -
NEHPDDFL_01995 1.56e-22 - - - - - - - -
NEHPDDFL_01996 1.07e-26 - - - - - - - -
NEHPDDFL_01997 9.35e-24 - - - - - - - -
NEHPDDFL_01998 9.35e-24 - - - - - - - -
NEHPDDFL_01999 9.35e-24 - - - - - - - -
NEHPDDFL_02000 2.16e-26 - - - - - - - -
NEHPDDFL_02001 4.63e-24 - - - - - - - -
NEHPDDFL_02002 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
NEHPDDFL_02003 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEHPDDFL_02004 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02005 2.1e-33 - - - - - - - -
NEHPDDFL_02006 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NEHPDDFL_02007 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
NEHPDDFL_02008 5.23e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
NEHPDDFL_02009 0.0 yclK - - T - - - Histidine kinase
NEHPDDFL_02010 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NEHPDDFL_02011 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NEHPDDFL_02012 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NEHPDDFL_02013 1.26e-218 - - - EG - - - EamA-like transporter family
NEHPDDFL_02015 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
NEHPDDFL_02016 5.34e-64 - - - - - - - -
NEHPDDFL_02017 6.83e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
NEHPDDFL_02018 8.05e-178 - - - F - - - NUDIX domain
NEHPDDFL_02019 2.68e-32 - - - - - - - -
NEHPDDFL_02021 9.93e-208 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHPDDFL_02022 2.03e-221 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
NEHPDDFL_02023 5.92e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
NEHPDDFL_02024 2.29e-48 - - - - - - - -
NEHPDDFL_02025 1.11e-45 - - - - - - - -
NEHPDDFL_02026 2.81e-278 - - - T - - - diguanylate cyclase
NEHPDDFL_02027 0.0 - - - S - - - ABC transporter, ATP-binding protein
NEHPDDFL_02028 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
NEHPDDFL_02029 5.76e-107 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEHPDDFL_02030 9.2e-62 - - - - - - - -
NEHPDDFL_02031 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEHPDDFL_02032 1.31e-242 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEHPDDFL_02033 1.41e-208 - - - S - - - Uncharacterised protein, DegV family COG1307
NEHPDDFL_02034 1.01e-293 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
NEHPDDFL_02035 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NEHPDDFL_02036 1.53e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NEHPDDFL_02037 2.79e-226 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_02038 9.98e-195 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEHPDDFL_02039 1.14e-179 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02040 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NEHPDDFL_02041 2.34e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
NEHPDDFL_02042 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
NEHPDDFL_02043 2.37e-123 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEHPDDFL_02044 2.9e-253 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEHPDDFL_02045 4.37e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
NEHPDDFL_02046 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NEHPDDFL_02047 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEHPDDFL_02048 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NEHPDDFL_02049 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEHPDDFL_02050 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NEHPDDFL_02051 1.11e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEHPDDFL_02052 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NEHPDDFL_02053 2.3e-275 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NEHPDDFL_02054 6.46e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
NEHPDDFL_02055 1.51e-282 ysaA - - V - - - RDD family
NEHPDDFL_02056 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NEHPDDFL_02057 1.4e-66 - - - S - - - Domain of unknown function (DU1801)
NEHPDDFL_02058 2.54e-17 rmeB - - K - - - transcriptional regulator, MerR family
NEHPDDFL_02059 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEHPDDFL_02060 1.64e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEHPDDFL_02061 1.45e-46 - - - - - - - -
NEHPDDFL_02062 3.1e-144 - - - S - - - Protein of unknown function (DUF1211)
NEHPDDFL_02063 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
NEHPDDFL_02064 0.0 - - - M - - - domain protein
NEHPDDFL_02065 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
NEHPDDFL_02066 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEHPDDFL_02067 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NEHPDDFL_02068 4.01e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NEHPDDFL_02069 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHPDDFL_02070 7.24e-250 - - - S - - - domain, Protein
NEHPDDFL_02071 1.73e-216 - - - S - - - Polyphosphate kinase 2 (PPK2)
NEHPDDFL_02072 2.57e-128 - - - C - - - Nitroreductase family
NEHPDDFL_02073 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
NEHPDDFL_02074 1.03e-210 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEHPDDFL_02075 1.91e-198 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NEHPDDFL_02076 1.79e-92 - - - GK - - - ROK family
NEHPDDFL_02077 1.13e-112 - - - GK - - - ROK family
NEHPDDFL_02078 2.08e-199 - 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEHPDDFL_02079 1.18e-172 rdrA - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NEHPDDFL_02080 0.0 pflD 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
NEHPDDFL_02081 1.01e-226 - - - K - - - sugar-binding domain protein
NEHPDDFL_02082 1.81e-160 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
NEHPDDFL_02083 2.13e-182 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEHPDDFL_02084 2.89e-224 ccpB - - K - - - lacI family
NEHPDDFL_02085 5.28e-203 - - - K - - - Helix-turn-helix domain, rpiR family
NEHPDDFL_02086 5e-227 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NEHPDDFL_02087 4.45e-253 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NEHPDDFL_02088 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
NEHPDDFL_02089 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEHPDDFL_02090 9.38e-139 pncA - - Q - - - Isochorismatase family
NEHPDDFL_02091 1.54e-171 - - - - - - - -
NEHPDDFL_02092 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_02093 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
NEHPDDFL_02094 7.2e-61 - - - S - - - Enterocin A Immunity
NEHPDDFL_02095 3.25e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
NEHPDDFL_02096 0.0 pepF2 - - E - - - Oligopeptidase F
NEHPDDFL_02097 1.4e-95 - - - K - - - Transcriptional regulator
NEHPDDFL_02098 2.64e-210 - - - - - - - -
NEHPDDFL_02100 2.49e-75 - - - - - - - -
NEHPDDFL_02101 2.8e-63 - - - - - - - -
NEHPDDFL_02102 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NEHPDDFL_02103 1.17e-88 - - - - - - - -
NEHPDDFL_02104 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
NEHPDDFL_02105 9.89e-74 ytpP - - CO - - - Thioredoxin
NEHPDDFL_02106 3.87e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
NEHPDDFL_02107 3.89e-62 - - - - - - - -
NEHPDDFL_02108 1.57e-71 - - - - - - - -
NEHPDDFL_02109 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
NEHPDDFL_02110 4.05e-98 - - - - - - - -
NEHPDDFL_02111 4.15e-78 - - - - - - - -
NEHPDDFL_02112 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NEHPDDFL_02113 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
NEHPDDFL_02114 1.02e-102 uspA3 - - T - - - universal stress protein
NEHPDDFL_02115 1.02e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NEHPDDFL_02116 2.73e-24 - - - - - - - -
NEHPDDFL_02117 1.09e-55 - - - S - - - zinc-ribbon domain
NEHPDDFL_02118 8.5e-98 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NEHPDDFL_02119 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
NEHPDDFL_02120 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
NEHPDDFL_02121 7.54e-285 - - - M - - - Glycosyl transferases group 1
NEHPDDFL_02122 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NEHPDDFL_02123 7.86e-207 - - - S - - - Putative esterase
NEHPDDFL_02124 3.53e-169 - - - K - - - Transcriptional regulator
NEHPDDFL_02125 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEHPDDFL_02126 6.08e-179 - - - - - - - -
NEHPDDFL_02127 1.97e-150 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHPDDFL_02128 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
NEHPDDFL_02129 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
NEHPDDFL_02130 1.55e-79 - - - - - - - -
NEHPDDFL_02131 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NEHPDDFL_02132 2.97e-76 - - - - - - - -
NEHPDDFL_02133 0.0 yhdP - - S - - - Transporter associated domain
NEHPDDFL_02134 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NEHPDDFL_02135 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NEHPDDFL_02136 3.36e-270 yttB - - EGP - - - Major Facilitator
NEHPDDFL_02137 8.13e-82 - - - K - - - helix_turn_helix, mercury resistance
NEHPDDFL_02138 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
NEHPDDFL_02139 4.71e-74 - - - S - - - SdpI/YhfL protein family
NEHPDDFL_02140 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEHPDDFL_02141 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
NEHPDDFL_02142 2.91e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NEHPDDFL_02143 1.84e-204 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEHPDDFL_02144 3.59e-26 - - - - - - - -
NEHPDDFL_02145 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
NEHPDDFL_02146 5.73e-208 mleR - - K - - - LysR family
NEHPDDFL_02147 1.29e-148 - - - GM - - - NAD(P)H-binding
NEHPDDFL_02148 1.57e-123 - - - K - - - Acetyltransferase (GNAT) family
NEHPDDFL_02149 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NEHPDDFL_02150 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NEHPDDFL_02151 6.45e-216 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
NEHPDDFL_02152 4.49e-144 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEHPDDFL_02153 1.09e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NEHPDDFL_02154 4.24e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEHPDDFL_02155 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NEHPDDFL_02156 2.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NEHPDDFL_02157 1.95e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEHPDDFL_02158 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NEHPDDFL_02159 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEHPDDFL_02160 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
NEHPDDFL_02161 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NEHPDDFL_02162 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
NEHPDDFL_02163 2.24e-206 - - - GM - - - NmrA-like family
NEHPDDFL_02164 1.25e-199 - - - T - - - EAL domain
NEHPDDFL_02165 2.62e-121 - - - - - - - -
NEHPDDFL_02166 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
NEHPDDFL_02167 4.17e-163 - - - E - - - Methionine synthase
NEHPDDFL_02168 2.71e-280 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NEHPDDFL_02169 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NEHPDDFL_02170 2.55e-131 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NEHPDDFL_02171 5.35e-246 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NEHPDDFL_02172 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEHPDDFL_02173 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEHPDDFL_02174 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEHPDDFL_02175 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEHPDDFL_02176 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NEHPDDFL_02177 1e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEHPDDFL_02178 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEHPDDFL_02179 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NEHPDDFL_02180 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
NEHPDDFL_02181 2.01e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
NEHPDDFL_02182 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NEHPDDFL_02183 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
NEHPDDFL_02184 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHPDDFL_02185 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
NEHPDDFL_02186 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02187 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEHPDDFL_02188 4.76e-56 - - - - - - - -
NEHPDDFL_02189 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
NEHPDDFL_02190 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02191 3.41e-190 - - - - - - - -
NEHPDDFL_02192 2.7e-104 usp5 - - T - - - universal stress protein
NEHPDDFL_02193 7.35e-46 - - - - - - - -
NEHPDDFL_02194 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
NEHPDDFL_02195 1.76e-114 - - - - - - - -
NEHPDDFL_02196 4.87e-66 - - - - - - - -
NEHPDDFL_02197 4.79e-13 - - - - - - - -
NEHPDDFL_02198 4.63e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NEHPDDFL_02199 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
NEHPDDFL_02200 4.34e-151 - - - - - - - -
NEHPDDFL_02201 1.21e-69 - - - - - - - -
NEHPDDFL_02203 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NEHPDDFL_02204 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NEHPDDFL_02205 1.1e-184 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEHPDDFL_02206 2.38e-37 - - - S - - - Pentapeptide repeats (8 copies)
NEHPDDFL_02207 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEHPDDFL_02208 5.38e-131 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NEHPDDFL_02209 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
NEHPDDFL_02210 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NEHPDDFL_02211 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
NEHPDDFL_02212 6.01e-270 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
NEHPDDFL_02213 4.43e-294 - - - S - - - Sterol carrier protein domain
NEHPDDFL_02214 5.78e-288 - - - EGP - - - Transmembrane secretion effector
NEHPDDFL_02215 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
NEHPDDFL_02216 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEHPDDFL_02217 2.13e-152 - - - K - - - Transcriptional regulator
NEHPDDFL_02218 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_02219 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NEHPDDFL_02220 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NEHPDDFL_02221 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_02222 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_02223 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
NEHPDDFL_02224 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEHPDDFL_02225 7.44e-168 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
NEHPDDFL_02226 1.4e-181 epsV - - S - - - glycosyl transferase family 2
NEHPDDFL_02227 1.02e-155 pgm7 - - G - - - Phosphoglycerate mutase family
NEHPDDFL_02228 7.63e-107 - - - - - - - -
NEHPDDFL_02229 5.06e-196 - - - S - - - hydrolase
NEHPDDFL_02230 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEHPDDFL_02231 3.98e-204 - - - EG - - - EamA-like transporter family
NEHPDDFL_02232 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NEHPDDFL_02233 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NEHPDDFL_02234 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
NEHPDDFL_02235 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
NEHPDDFL_02236 0.0 - - - M - - - Domain of unknown function (DUF5011)
NEHPDDFL_02237 1.08e-81 - - - M - - - Domain of unknown function (DUF5011)
NEHPDDFL_02238 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
NEHPDDFL_02239 4.3e-44 - - - - - - - -
NEHPDDFL_02240 5.59e-163 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
NEHPDDFL_02241 0.0 ycaM - - E - - - amino acid
NEHPDDFL_02242 2e-100 - - - K - - - Winged helix DNA-binding domain
NEHPDDFL_02243 8.21e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
NEHPDDFL_02244 5.11e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEHPDDFL_02245 1.3e-209 - - - K - - - Transcriptional regulator
NEHPDDFL_02248 7.66e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEHPDDFL_02249 1.78e-240 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NEHPDDFL_02250 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NEHPDDFL_02251 2.75e-216 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
NEHPDDFL_02252 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEHPDDFL_02253 3.35e-157 - - - - - - - -
NEHPDDFL_02254 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEHPDDFL_02255 0.0 mdr - - EGP - - - Major Facilitator
NEHPDDFL_02256 3.78e-304 - - - N - - - Cell shape-determining protein MreB
NEHPDDFL_02257 0.0 - - - S - - - Pfam Methyltransferase
NEHPDDFL_02258 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEHPDDFL_02259 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEHPDDFL_02260 9.32e-40 - - - - - - - -
NEHPDDFL_02261 3.03e-122 mraW1 - - J - - - Putative rRNA methylase
NEHPDDFL_02262 1.03e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NEHPDDFL_02263 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NEHPDDFL_02264 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NEHPDDFL_02265 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NEHPDDFL_02266 5.24e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEHPDDFL_02267 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NEHPDDFL_02268 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
NEHPDDFL_02269 1.02e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
NEHPDDFL_02270 4.39e-219 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHPDDFL_02271 1.77e-192 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_02272 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NEHPDDFL_02273 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NEHPDDFL_02274 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
NEHPDDFL_02275 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEHPDDFL_02276 1.48e-315 XK27_06930 - - V ko:K01421 - ko00000 domain protein
NEHPDDFL_02278 1.16e-160 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
NEHPDDFL_02279 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_02280 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
NEHPDDFL_02282 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEHPDDFL_02283 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
NEHPDDFL_02284 1.64e-151 - - - GM - - - NAD(P)H-binding
NEHPDDFL_02285 3.81e-204 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NEHPDDFL_02286 1.97e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEHPDDFL_02287 7.83e-140 - - - - - - - -
NEHPDDFL_02288 8.83e-285 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEHPDDFL_02289 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEHPDDFL_02290 5.37e-74 - - - - - - - -
NEHPDDFL_02291 4.56e-78 - - - - - - - -
NEHPDDFL_02292 1.06e-146 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_02293 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NEHPDDFL_02294 1.25e-118 - - - - - - - -
NEHPDDFL_02295 7.12e-62 - - - - - - - -
NEHPDDFL_02296 0.0 uvrA2 - - L - - - ABC transporter
NEHPDDFL_02298 3.19e-120 int3 - - L - - - Belongs to the 'phage' integrase family
NEHPDDFL_02299 7e-39 - - - - - - - -
NEHPDDFL_02300 1.82e-115 - - - S - - - Protein of unknown function DUF262
NEHPDDFL_02301 2.38e-194 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NEHPDDFL_02305 1.65e-39 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHPDDFL_02306 1.32e-19 - - - K - - - Helix-turn-helix
NEHPDDFL_02307 3.2e-11 - - - - - - - -
NEHPDDFL_02308 6.21e-36 - - - S - - - Domain of unknown function (DUF771)
NEHPDDFL_02315 3.18e-53 - - - S - - - Siphovirus Gp157
NEHPDDFL_02316 5.54e-221 - - - S - - - helicase activity
NEHPDDFL_02317 1.64e-10 - - - S - - - HNH endonuclease
NEHPDDFL_02318 3.29e-92 - - - L - - - AAA domain
NEHPDDFL_02319 3.52e-28 - - - - - - - -
NEHPDDFL_02320 2.31e-95 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
NEHPDDFL_02321 6.4e-166 - - - S ko:K06919 - ko00000 Virulence-associated protein E
NEHPDDFL_02322 7.72e-51 - - - S - - - hydrolase activity, acting on ester bonds
NEHPDDFL_02326 2.02e-43 - - - - - - - -
NEHPDDFL_02331 8.83e-35 - - - V - - - HNH nucleases
NEHPDDFL_02334 1.51e-18 - - - - - - - -
NEHPDDFL_02335 9.32e-224 - - - S - - - Phage Terminase
NEHPDDFL_02336 4.07e-127 - - - S - - - Phage portal protein
NEHPDDFL_02337 5.71e-71 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
NEHPDDFL_02338 2.59e-140 - - - S - - - Phage capsid family
NEHPDDFL_02339 1.01e-24 - - - - - - - -
NEHPDDFL_02340 3.5e-31 - - - - - - - -
NEHPDDFL_02341 1.32e-44 - - - - - - - -
NEHPDDFL_02342 3.69e-28 - - - - - - - -
NEHPDDFL_02343 1.07e-43 - - - S - - - Phage tail tube protein
NEHPDDFL_02345 1.59e-213 - - - L - - - Phage tail tape measure protein TP901
NEHPDDFL_02347 4.81e-98 - - - L - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEHPDDFL_02350 4.34e-55 - - - - - - - -
NEHPDDFL_02352 1.78e-07 - - - S - - - Bacteriophage A118-like holin, Hol118
NEHPDDFL_02353 1.61e-135 - - - M - - - Glycosyl hydrolases family 25
NEHPDDFL_02355 4.29e-87 - - - - - - - -
NEHPDDFL_02356 9.03e-16 - - - - - - - -
NEHPDDFL_02357 3.89e-237 - - - - - - - -
NEHPDDFL_02358 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
NEHPDDFL_02359 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
NEHPDDFL_02360 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NEHPDDFL_02361 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEHPDDFL_02362 0.0 - - - S - - - Protein conserved in bacteria
NEHPDDFL_02363 1.8e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
NEHPDDFL_02364 3.72e-145 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NEHPDDFL_02365 3.1e-226 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
NEHPDDFL_02366 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
NEHPDDFL_02367 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
NEHPDDFL_02368 2.69e-316 dinF - - V - - - MatE
NEHPDDFL_02369 1.79e-42 - - - - - - - -
NEHPDDFL_02372 7.02e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
NEHPDDFL_02373 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NEHPDDFL_02374 2.91e-109 - - - - - - - -
NEHPDDFL_02375 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NEHPDDFL_02376 6.25e-138 - - - - - - - -
NEHPDDFL_02377 0.0 celR - - K - - - PRD domain
NEHPDDFL_02378 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
NEHPDDFL_02379 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
NEHPDDFL_02380 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEHPDDFL_02381 1.69e-284 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_02382 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_02383 1.14e-191 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
NEHPDDFL_02384 1.1e-70 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
NEHPDDFL_02385 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
NEHPDDFL_02386 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPDDFL_02387 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
NEHPDDFL_02388 3.29e-132 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
NEHPDDFL_02389 5.58e-271 arcT - - E - - - Aminotransferase
NEHPDDFL_02390 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NEHPDDFL_02391 2.43e-18 - - - - - - - -
NEHPDDFL_02392 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NEHPDDFL_02393 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
NEHPDDFL_02394 1.05e-294 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
NEHPDDFL_02395 0.0 yhaN - - L - - - AAA domain
NEHPDDFL_02396 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHPDDFL_02397 9.12e-277 - - - - - - - -
NEHPDDFL_02398 3.16e-116 - - - M - - - Peptidase family S41
NEHPDDFL_02399 2.39e-66 - - - M - - - Peptidase family S41
NEHPDDFL_02400 6.59e-227 - - - K - - - LysR substrate binding domain
NEHPDDFL_02401 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
NEHPDDFL_02402 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEHPDDFL_02403 4.26e-127 - - - - - - - -
NEHPDDFL_02404 2.76e-99 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
NEHPDDFL_02405 4.68e-235 ykoT - - M - - - Glycosyl transferase family 2
NEHPDDFL_02406 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEHPDDFL_02407 6.95e-91 - - - S - - - NUDIX domain
NEHPDDFL_02408 0.0 - - - S - - - membrane
NEHPDDFL_02409 3.49e-217 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NEHPDDFL_02410 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NEHPDDFL_02411 2.96e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NEHPDDFL_02412 4.28e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NEHPDDFL_02413 6.49e-91 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
NEHPDDFL_02414 3.39e-138 - - - - - - - -
NEHPDDFL_02415 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
NEHPDDFL_02416 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_02417 8.6e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
NEHPDDFL_02418 0.0 - - - - - - - -
NEHPDDFL_02419 1.65e-80 - - - - - - - -
NEHPDDFL_02420 2.76e-247 - - - S - - - Fn3-like domain
NEHPDDFL_02421 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
NEHPDDFL_02422 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
NEHPDDFL_02423 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEHPDDFL_02424 6.76e-73 - - - - - - - -
NEHPDDFL_02425 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NEHPDDFL_02426 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02427 9.53e-284 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_02428 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
NEHPDDFL_02429 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEHPDDFL_02430 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
NEHPDDFL_02431 1.45e-145 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEHPDDFL_02432 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NEHPDDFL_02433 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NEHPDDFL_02434 3.04e-29 - - - S - - - Virus attachment protein p12 family
NEHPDDFL_02435 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NEHPDDFL_02436 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
NEHPDDFL_02437 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NEHPDDFL_02438 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NEHPDDFL_02439 1.57e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEHPDDFL_02440 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NEHPDDFL_02441 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NEHPDDFL_02442 1.72e-245 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NEHPDDFL_02443 1.14e-177 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NEHPDDFL_02444 5.63e-212 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPDDFL_02445 1.92e-106 - - - C - - - Flavodoxin
NEHPDDFL_02446 6.26e-92 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
NEHPDDFL_02447 7.86e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
NEHPDDFL_02448 1.13e-247 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NEHPDDFL_02449 1.98e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
NEHPDDFL_02450 4.08e-78 - - - S - - - Iron-sulfur cluster assembly protein
NEHPDDFL_02451 7.79e-203 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NEHPDDFL_02452 4.87e-205 - - - H - - - geranyltranstransferase activity
NEHPDDFL_02453 4.32e-233 - - - - - - - -
NEHPDDFL_02454 3.67e-65 - - - - - - - -
NEHPDDFL_02455 5.46e-152 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
NEHPDDFL_02456 6.71e-241 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
NEHPDDFL_02457 1.48e-98 - 2.7.13.3 - T ko:K07683,ko:K10851 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 phosphoenolpyruvate-protein phosphotransferase activity
NEHPDDFL_02458 3.6e-51 - - - - - - - -
NEHPDDFL_02459 5.73e-129 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NEHPDDFL_02460 1.08e-111 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NEHPDDFL_02461 2.87e-117 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NEHPDDFL_02462 1.55e-295 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
NEHPDDFL_02463 1.34e-108 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NEHPDDFL_02464 1.17e-246 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
NEHPDDFL_02465 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEHPDDFL_02466 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
NEHPDDFL_02467 1.17e-126 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
NEHPDDFL_02468 2.69e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
NEHPDDFL_02469 3.51e-225 - - - - - - - -
NEHPDDFL_02470 2.43e-95 - - - - - - - -
NEHPDDFL_02472 6.43e-48 - - - S - - - Phage Mu protein F like protein
NEHPDDFL_02474 1.27e-57 - - - S - - - Phage minor structural protein GP20
NEHPDDFL_02475 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NEHPDDFL_02476 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEHPDDFL_02477 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NEHPDDFL_02478 9.54e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEHPDDFL_02479 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEHPDDFL_02480 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NEHPDDFL_02481 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NEHPDDFL_02482 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEHPDDFL_02483 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEHPDDFL_02484 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NEHPDDFL_02485 1.97e-72 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEHPDDFL_02486 2.76e-74 - - - - - - - -
NEHPDDFL_02487 1.07e-127 - - - L ko:K07478 - ko00000 AAA C-terminal domain
NEHPDDFL_02488 4.34e-137 - - - L ko:K07478 - ko00000 AAA C-terminal domain
NEHPDDFL_02489 1.43e-251 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NEHPDDFL_02490 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
NEHPDDFL_02491 9.75e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NEHPDDFL_02492 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
NEHPDDFL_02493 4.28e-112 - - - - - - - -
NEHPDDFL_02494 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NEHPDDFL_02495 3.81e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NEHPDDFL_02496 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NEHPDDFL_02497 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEHPDDFL_02498 1.71e-149 yqeK - - H - - - Hydrolase, HD family
NEHPDDFL_02499 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEHPDDFL_02500 3.3e-180 yqeM - - Q - - - Methyltransferase
NEHPDDFL_02501 1.24e-279 ylbM - - S - - - Belongs to the UPF0348 family
NEHPDDFL_02502 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NEHPDDFL_02503 1.3e-125 - - - S - - - Peptidase propeptide and YPEB domain
NEHPDDFL_02504 9.32e-225 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEHPDDFL_02505 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEHPDDFL_02506 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NEHPDDFL_02507 1.38e-155 csrR - - K - - - response regulator
NEHPDDFL_02508 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NEHPDDFL_02509 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NEHPDDFL_02510 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NEHPDDFL_02511 2.36e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NEHPDDFL_02512 1.21e-129 - - - S - - - SdpI/YhfL protein family
NEHPDDFL_02513 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEHPDDFL_02514 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NEHPDDFL_02515 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEHPDDFL_02516 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHPDDFL_02517 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
NEHPDDFL_02518 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEHPDDFL_02519 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEHPDDFL_02520 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEHPDDFL_02521 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NEHPDDFL_02522 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEHPDDFL_02523 9.72e-146 - - - S - - - membrane
NEHPDDFL_02524 5.72e-99 - - - K - - - LytTr DNA-binding domain
NEHPDDFL_02525 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
NEHPDDFL_02526 0.0 - - - S - - - membrane
NEHPDDFL_02527 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NEHPDDFL_02528 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NEHPDDFL_02529 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NEHPDDFL_02530 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NEHPDDFL_02531 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NEHPDDFL_02532 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NEHPDDFL_02533 6.61e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NEHPDDFL_02534 2.72e-88 yqhL - - P - - - Rhodanese-like protein
NEHPDDFL_02535 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
NEHPDDFL_02536 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
NEHPDDFL_02537 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEHPDDFL_02538 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
NEHPDDFL_02539 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NEHPDDFL_02540 1.77e-205 - - - - - - - -
NEHPDDFL_02541 1.34e-232 - - - - - - - -
NEHPDDFL_02542 3.55e-127 - - - S - - - Protein conserved in bacteria
NEHPDDFL_02543 1.87e-74 - - - - - - - -
NEHPDDFL_02544 2.97e-41 - - - - - - - -
NEHPDDFL_02547 9.81e-27 - - - - - - - -
NEHPDDFL_02548 8.15e-125 - - - K - - - Transcriptional regulator
NEHPDDFL_02549 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NEHPDDFL_02550 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NEHPDDFL_02551 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NEHPDDFL_02552 2.46e-248 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NEHPDDFL_02553 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEHPDDFL_02554 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NEHPDDFL_02555 1.57e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEHPDDFL_02556 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEHPDDFL_02557 2.81e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEHPDDFL_02558 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEHPDDFL_02559 6.68e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEHPDDFL_02560 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NEHPDDFL_02561 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NEHPDDFL_02562 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NEHPDDFL_02563 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02564 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_02565 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEHPDDFL_02566 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NEHPDDFL_02567 8.28e-73 - - - - - - - -
NEHPDDFL_02568 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NEHPDDFL_02569 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEHPDDFL_02570 2.05e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NEHPDDFL_02571 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEHPDDFL_02572 5.2e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEHPDDFL_02573 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NEHPDDFL_02574 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NEHPDDFL_02575 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NEHPDDFL_02576 1.21e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEHPDDFL_02577 3.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NEHPDDFL_02578 2.61e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NEHPDDFL_02579 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NEHPDDFL_02580 4.51e-84 - - - K - - - helix_turn_helix, mercury resistance
NEHPDDFL_02581 1.5e-193 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NEHPDDFL_02582 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NEHPDDFL_02583 7.07e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPDDFL_02584 3.89e-210 - - - GM - - - NmrA-like family
NEHPDDFL_02585 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_02586 3.32e-219 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPDDFL_02587 1.81e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPDDFL_02588 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEHPDDFL_02589 4.76e-217 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NEHPDDFL_02590 2.64e-141 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_02591 0.0 yfjF - - U - - - Sugar (and other) transporter
NEHPDDFL_02592 6.6e-228 ydhF - - S - - - Aldo keto reductase
NEHPDDFL_02593 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
NEHPDDFL_02594 9.95e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
NEHPDDFL_02595 2.46e-127 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_02596 3.27e-170 - - - S - - - KR domain
NEHPDDFL_02597 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
NEHPDDFL_02598 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
NEHPDDFL_02599 0.0 - - - M - - - Glycosyl hydrolases family 25
NEHPDDFL_02600 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NEHPDDFL_02601 5.35e-216 - - - GM - - - NmrA-like family
NEHPDDFL_02602 3.75e-129 - - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_02603 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEHPDDFL_02604 1.38e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEHPDDFL_02605 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NEHPDDFL_02606 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
NEHPDDFL_02607 1.81e-272 - - - EGP - - - Major Facilitator
NEHPDDFL_02608 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
NEHPDDFL_02609 1.83e-150 - - - S - - - Haloacid dehalogenase-like hydrolase
NEHPDDFL_02610 4.13e-157 - - - - - - - -
NEHPDDFL_02611 8.75e-306 - - - NU - - - Mycoplasma protein of unknown function, DUF285
NEHPDDFL_02612 1.47e-83 - - - - - - - -
NEHPDDFL_02613 4.48e-130 - - - S - - - WxL domain surface cell wall-binding
NEHPDDFL_02614 5.08e-240 ynjC - - S - - - Cell surface protein
NEHPDDFL_02615 3.33e-149 - - - S - - - GyrI-like small molecule binding domain
NEHPDDFL_02616 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
NEHPDDFL_02617 5.4e-225 - - - C - - - Alcohol dehydrogenase GroES-like domain
NEHPDDFL_02618 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
NEHPDDFL_02619 1.11e-240 - - - S - - - Cell surface protein
NEHPDDFL_02620 2.69e-99 - - - - - - - -
NEHPDDFL_02621 0.0 - - - - - - - -
NEHPDDFL_02622 1.77e-288 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEHPDDFL_02623 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
NEHPDDFL_02624 2.81e-181 - - - K - - - Helix-turn-helix domain
NEHPDDFL_02625 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NEHPDDFL_02626 1.36e-84 - - - S - - - Cupredoxin-like domain
NEHPDDFL_02627 3.65e-59 - - - S - - - Cupredoxin-like domain
NEHPDDFL_02628 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NEHPDDFL_02629 2.77e-271 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
NEHPDDFL_02630 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
NEHPDDFL_02631 1.67e-86 lysM - - M - - - LysM domain
NEHPDDFL_02632 0.0 - - - E - - - Amino Acid
NEHPDDFL_02633 1.74e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHPDDFL_02634 9.38e-91 - - - - - - - -
NEHPDDFL_02636 2.43e-208 yhxD - - IQ - - - KR domain
NEHPDDFL_02637 1.67e-292 amd - - E - - - Peptidase family M20/M25/M40
NEHPDDFL_02638 1.3e-226 - - - O - - - protein import
NEHPDDFL_02639 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02640 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_02641 2.31e-277 - - - - - - - -
NEHPDDFL_02642 3.41e-151 - - - GM - - - NAD(P)H-binding
NEHPDDFL_02643 3.83e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
NEHPDDFL_02644 3.55e-79 - - - I - - - sulfurtransferase activity
NEHPDDFL_02645 6.7e-102 yphH - - S - - - Cupin domain
NEHPDDFL_02646 1.17e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NEHPDDFL_02647 3.57e-150 - - - GM - - - NAD(P)H-binding
NEHPDDFL_02648 1.88e-222 - - - C - - - C4-dicarboxylate transmembrane transporter activity
NEHPDDFL_02649 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPDDFL_02650 3.05e-95 - - - - - - - -
NEHPDDFL_02651 2.02e-215 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
NEHPDDFL_02652 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
NEHPDDFL_02653 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
NEHPDDFL_02654 3.55e-281 - - - T - - - diguanylate cyclase
NEHPDDFL_02655 2.72e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
NEHPDDFL_02656 4.94e-93 - - - - - - - -
NEHPDDFL_02657 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEHPDDFL_02658 1.58e-72 nudA - - S - - - ASCH
NEHPDDFL_02659 9.47e-137 - - - S - - - SdpI/YhfL protein family
NEHPDDFL_02660 3.03e-130 - - - M - - - Lysin motif
NEHPDDFL_02661 4.61e-101 - - - M - - - LysM domain
NEHPDDFL_02662 2.1e-99 - - - K - - - helix_turn_helix, mercury resistance
NEHPDDFL_02663 1.57e-237 - - - GM - - - Male sterility protein
NEHPDDFL_02664 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_02665 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_02666 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
NEHPDDFL_02667 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEHPDDFL_02668 1.24e-194 - - - K - - - Helix-turn-helix domain
NEHPDDFL_02669 9.98e-73 - - - - - - - -
NEHPDDFL_02670 1.58e-204 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NEHPDDFL_02671 2.03e-84 - - - - - - - -
NEHPDDFL_02672 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
NEHPDDFL_02673 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02674 1.53e-123 - - - P - - - Cadmium resistance transporter
NEHPDDFL_02675 1e-63 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NEHPDDFL_02676 1.04e-149 - - - S - - - SNARE associated Golgi protein
NEHPDDFL_02677 2.87e-61 - - - - - - - -
NEHPDDFL_02678 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
NEHPDDFL_02679 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NEHPDDFL_02680 4.08e-158 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHPDDFL_02681 2.88e-106 gtcA3 - - S - - - GtrA-like protein
NEHPDDFL_02682 2.81e-167 zmp3 - - O - - - Zinc-dependent metalloprotease
NEHPDDFL_02683 1.15e-43 - - - - - - - -
NEHPDDFL_02685 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
NEHPDDFL_02686 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NEHPDDFL_02687 1.47e-189 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
NEHPDDFL_02688 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
NEHPDDFL_02689 7.96e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_02690 1.91e-124 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NEHPDDFL_02691 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
NEHPDDFL_02692 1.02e-237 - - - S - - - Cell surface protein
NEHPDDFL_02693 5.73e-82 - - - - - - - -
NEHPDDFL_02694 0.0 - - - - - - - -
NEHPDDFL_02695 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NEHPDDFL_02696 2.48e-199 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NEHPDDFL_02697 1.21e-149 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NEHPDDFL_02698 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
NEHPDDFL_02699 8.08e-154 ydgI3 - - C - - - Nitroreductase family
NEHPDDFL_02700 5.24e-124 - - - K - - - Transcriptional regulator, MarR family
NEHPDDFL_02701 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NEHPDDFL_02702 3.73e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEHPDDFL_02703 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
NEHPDDFL_02704 2.15e-146 - - - K - - - Transcriptional regulator C-terminal region
NEHPDDFL_02705 2.04e-226 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
NEHPDDFL_02706 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
NEHPDDFL_02707 6.92e-206 yicL - - EG - - - EamA-like transporter family
NEHPDDFL_02708 6e-299 - - - M - - - Collagen binding domain
NEHPDDFL_02709 0.0 - - - I - - - acetylesterase activity
NEHPDDFL_02710 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NEHPDDFL_02711 2.99e-171 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
NEHPDDFL_02712 4.29e-50 - - - - - - - -
NEHPDDFL_02714 1.37e-182 - - - S - - - zinc-ribbon domain
NEHPDDFL_02715 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NEHPDDFL_02716 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NEHPDDFL_02717 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
NEHPDDFL_02718 5.12e-212 - - - K - - - LysR substrate binding domain
NEHPDDFL_02719 1.37e-12 - - - - - - - -
NEHPDDFL_02720 3.78e-105 - - - - - - - -
NEHPDDFL_02721 3.7e-30 - - - - - - - -
NEHPDDFL_02722 2.97e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEHPDDFL_02723 1.59e-243 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEHPDDFL_02724 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NEHPDDFL_02725 1.56e-108 - - - - - - - -
NEHPDDFL_02726 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NEHPDDFL_02727 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEHPDDFL_02728 2.82e-163 - - - T - - - Putative diguanylate phosphodiesterase
NEHPDDFL_02729 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
NEHPDDFL_02730 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEHPDDFL_02731 2e-52 - - - S - - - Cytochrome B5
NEHPDDFL_02732 0.0 - - - - - - - -
NEHPDDFL_02733 6.11e-169 treR - - K ko:K03486 - ko00000,ko03000 UTRA
NEHPDDFL_02734 1.65e-205 - - - I - - - alpha/beta hydrolase fold
NEHPDDFL_02735 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
NEHPDDFL_02736 2.51e-298 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NEHPDDFL_02737 0.0 - - - E ko:K03294 - ko00000 Amino acid permease
NEHPDDFL_02738 5.22e-229 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NEHPDDFL_02739 2.78e-222 ropB - - K - - - Helix-turn-helix XRE-family like proteins
NEHPDDFL_02740 2.84e-266 - - - EGP - - - Major facilitator Superfamily
NEHPDDFL_02741 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
NEHPDDFL_02742 0.0 - - - S - - - Predicted membrane protein (DUF2207)
NEHPDDFL_02743 1.9e-189 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NEHPDDFL_02744 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
NEHPDDFL_02745 2.09e-287 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_02746 3.05e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEHPDDFL_02747 9.05e-140 yokL3 - - J - - - Acetyltransferase (GNAT) domain
NEHPDDFL_02748 1.66e-199 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
NEHPDDFL_02749 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPDDFL_02750 9.22e-143 - - - K - - - Transcriptional regulator (TetR family)
NEHPDDFL_02751 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
NEHPDDFL_02753 1.11e-314 - - - EGP - - - Major Facilitator
NEHPDDFL_02754 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_02755 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NEHPDDFL_02757 2.02e-246 - - - C - - - Aldo/keto reductase family
NEHPDDFL_02758 1.52e-131 - - - M - - - Protein of unknown function (DUF3737)
NEHPDDFL_02759 3.45e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
NEHPDDFL_02760 3.73e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
NEHPDDFL_02761 1.12e-105 - - - - - - - -
NEHPDDFL_02762 2.4e-160 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEHPDDFL_02763 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NEHPDDFL_02764 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
NEHPDDFL_02765 5.55e-106 - - - GM - - - NAD(P)H-binding
NEHPDDFL_02766 3.08e-178 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
NEHPDDFL_02767 4.02e-181 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEHPDDFL_02768 2.41e-165 - - - C - - - Aldo keto reductase
NEHPDDFL_02769 9.99e-147 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPDDFL_02770 1.69e-08 adhR - - K - - - helix_turn_helix, mercury resistance
NEHPDDFL_02771 1.03e-31 - - - C - - - Flavodoxin
NEHPDDFL_02773 5.63e-98 - - - K - - - Transcriptional regulator
NEHPDDFL_02774 7.86e-138 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEHPDDFL_02775 1.06e-110 - - - GM - - - NAD(P)H-binding
NEHPDDFL_02776 1.07e-116 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NEHPDDFL_02777 1.38e-160 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
NEHPDDFL_02778 2.47e-97 - - - C - - - Flavodoxin
NEHPDDFL_02779 2.92e-106 - - - S - - - Protein of unknown function (DUF1211)
NEHPDDFL_02780 1.15e-179 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NEHPDDFL_02781 2.9e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NEHPDDFL_02782 2.03e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NEHPDDFL_02783 2.53e-134 - - - GM - - - NAD(P)H-binding
NEHPDDFL_02784 1.57e-202 - - - K - - - LysR substrate binding domain
NEHPDDFL_02785 2.65e-78 - - - S - - - Domain of unknown function (DUF4440)
NEHPDDFL_02786 5.46e-145 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
NEHPDDFL_02787 2.81e-64 - - - - - - - -
NEHPDDFL_02788 2.8e-49 - - - - - - - -
NEHPDDFL_02789 5.14e-111 yvbK - - K - - - GNAT family
NEHPDDFL_02790 2.82e-110 - - - - - - - -
NEHPDDFL_02791 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEHPDDFL_02792 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEHPDDFL_02793 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEHPDDFL_02795 2.03e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02796 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEHPDDFL_02797 5.3e-302 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NEHPDDFL_02798 1.27e-103 - - - K - - - transcriptional regulator, MerR family
NEHPDDFL_02799 4.77e-100 yphH - - S - - - Cupin domain
NEHPDDFL_02800 1.64e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NEHPDDFL_02801 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPDDFL_02802 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NEHPDDFL_02803 2.45e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02804 3.92e-120 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
NEHPDDFL_02805 4.5e-86 - - - M - - - LysM domain
NEHPDDFL_02806 4.93e-48 - - - M - - - LysM domain protein
NEHPDDFL_02807 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NEHPDDFL_02808 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
NEHPDDFL_02809 8.39e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NEHPDDFL_02810 2.17e-222 - - - S - - - Conserved hypothetical protein 698
NEHPDDFL_02811 8.99e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEHPDDFL_02812 4.03e-104 - - - S - - - Domain of unknown function (DUF4811)
NEHPDDFL_02813 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NEHPDDFL_02814 7.22e-163 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NEHPDDFL_02815 1.13e-256 - - - EGP - - - Major Facilitator Superfamily
NEHPDDFL_02816 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
NEHPDDFL_02817 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
NEHPDDFL_02818 9.01e-155 - - - S - - - Membrane
NEHPDDFL_02819 1.97e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEHPDDFL_02820 2.92e-126 ywjB - - H - - - RibD C-terminal domain
NEHPDDFL_02821 4.9e-239 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
NEHPDDFL_02822 2.76e-117 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
NEHPDDFL_02823 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_02824 1.2e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEHPDDFL_02825 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NEHPDDFL_02826 3.05e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEHPDDFL_02827 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
NEHPDDFL_02828 6.81e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NEHPDDFL_02829 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
NEHPDDFL_02830 3.84e-185 - - - S - - - Peptidase_C39 like family
NEHPDDFL_02831 1.08e-243 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEHPDDFL_02832 1.54e-144 - - - - - - - -
NEHPDDFL_02833 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEHPDDFL_02834 1.97e-110 - - - S - - - Pfam:DUF3816
NEHPDDFL_02835 5.65e-224 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEHPDDFL_02836 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEHPDDFL_02837 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
NEHPDDFL_02838 2.19e-111 - - - S - - - NusG domain II
NEHPDDFL_02839 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NEHPDDFL_02840 5.29e-193 - - - S - - - FMN_bind
NEHPDDFL_02841 2.53e-263 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEHPDDFL_02842 1.14e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHPDDFL_02843 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHPDDFL_02844 4.13e-185 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHPDDFL_02845 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEHPDDFL_02846 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEHPDDFL_02847 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NEHPDDFL_02848 8.51e-210 yitS - - S - - - Uncharacterised protein, DegV family COG1307
NEHPDDFL_02849 2.02e-234 - - - S - - - Membrane
NEHPDDFL_02850 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
NEHPDDFL_02851 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NEHPDDFL_02852 6.73e-211 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEHPDDFL_02853 4.68e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
NEHPDDFL_02854 1.23e-251 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NEHPDDFL_02856 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NEHPDDFL_02857 6.15e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
NEHPDDFL_02858 2.01e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
NEHPDDFL_02859 5.21e-226 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
NEHPDDFL_02860 1.55e-254 - - - K - - - Helix-turn-helix domain
NEHPDDFL_02861 5.24e-195 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NEHPDDFL_02862 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEHPDDFL_02863 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NEHPDDFL_02864 5.19e-223 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NEHPDDFL_02865 1.18e-66 - - - - - - - -
NEHPDDFL_02866 7.56e-214 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NEHPDDFL_02867 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NEHPDDFL_02868 8.69e-230 citR - - K - - - sugar-binding domain protein
NEHPDDFL_02869 1.3e-262 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
NEHPDDFL_02870 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NEHPDDFL_02871 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
NEHPDDFL_02872 9.11e-208 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
NEHPDDFL_02873 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
NEHPDDFL_02874 4.11e-217 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
NEHPDDFL_02875 1.89e-101 - - - K - - - sequence-specific DNA binding
NEHPDDFL_02879 4.91e-19 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NEHPDDFL_02880 1.06e-274 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NEHPDDFL_02881 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NEHPDDFL_02882 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NEHPDDFL_02883 1.98e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NEHPDDFL_02884 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
NEHPDDFL_02885 1.08e-213 mleR - - K - - - LysR family
NEHPDDFL_02886 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NEHPDDFL_02887 3.7e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
NEHPDDFL_02888 0.0 - - - E ko:K03294 - ko00000 Amino Acid
NEHPDDFL_02889 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
NEHPDDFL_02890 2.56e-34 - - - - - - - -
NEHPDDFL_02891 0.0 - - - S ko:K06889 - ko00000 Alpha beta
NEHPDDFL_02892 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NEHPDDFL_02893 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NEHPDDFL_02894 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NEHPDDFL_02895 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NEHPDDFL_02896 1.27e-206 - - - S - - - L,D-transpeptidase catalytic domain
NEHPDDFL_02897 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEHPDDFL_02898 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NEHPDDFL_02899 9.47e-236 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
NEHPDDFL_02900 2.92e-147 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NEHPDDFL_02901 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEHPDDFL_02902 1.13e-120 yebE - - S - - - UPF0316 protein
NEHPDDFL_02903 5.68e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEHPDDFL_02904 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NEHPDDFL_02905 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEHPDDFL_02906 9.48e-263 camS - - S - - - sex pheromone
NEHPDDFL_02907 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEHPDDFL_02908 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEHPDDFL_02909 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEHPDDFL_02910 4.55e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NEHPDDFL_02911 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEHPDDFL_02912 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
NEHPDDFL_02913 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
NEHPDDFL_02914 4.26e-308 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_02915 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHPDDFL_02916 5.63e-196 gntR - - K - - - rpiR family
NEHPDDFL_02917 1.1e-185 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NEHPDDFL_02918 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
NEHPDDFL_02919 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NEHPDDFL_02920 7.89e-245 mocA - - S - - - Oxidoreductase
NEHPDDFL_02921 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
NEHPDDFL_02923 3.93e-99 - - - T - - - Universal stress protein family
NEHPDDFL_02924 1.56e-313 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_02925 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NEHPDDFL_02927 7.62e-97 - - - - - - - -
NEHPDDFL_02928 2.9e-139 - - - - - - - -
NEHPDDFL_02929 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NEHPDDFL_02930 3.85e-280 pbpX - - V - - - Beta-lactamase
NEHPDDFL_02931 3.07e-263 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEHPDDFL_02932 7.42e-202 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NEHPDDFL_02933 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEHPDDFL_02934 5.9e-282 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NEHPDDFL_02935 7.14e-235 - - - M - - - Capsular polysaccharide synthesis protein
NEHPDDFL_02936 4.14e-256 - - - M - - - Glycosyl transferases group 1
NEHPDDFL_02937 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NEHPDDFL_02938 7.21e-191 cps1D - - M - - - Domain of unknown function (DUF4422)
NEHPDDFL_02939 2.42e-218 - - - S - - - transferase activity, transferring acyl groups other than amino-acyl groups
NEHPDDFL_02941 1.03e-267 - - - M - - - Glycosyl transferases group 1
NEHPDDFL_02942 1.74e-223 - - - S - - - Glycosyltransferase like family 2
NEHPDDFL_02944 1.24e-201 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NEHPDDFL_02945 3.8e-311 - - - G - - - PFAM glycoside hydrolase family 39
NEHPDDFL_02946 3.23e-139 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NEHPDDFL_02947 2.59e-258 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEHPDDFL_02948 2.95e-201 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NEHPDDFL_02949 3.9e-22 - - - L ko:K07497 - ko00000 hmm pf00665
NEHPDDFL_02950 9.61e-59 - - - L ko:K07497 - ko00000 hmm pf00665
NEHPDDFL_02951 3.62e-61 - - - L - - - Helix-turn-helix domain
NEHPDDFL_02952 4.4e-138 - - - L - - - Integrase
NEHPDDFL_02953 1.42e-171 epsB - - M - - - biosynthesis protein
NEHPDDFL_02954 7.38e-167 ywqD - - D - - - Capsular exopolysaccharide family
NEHPDDFL_02955 1.62e-182 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NEHPDDFL_02956 7.07e-222 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
NEHPDDFL_02957 2.81e-158 tuaA - - M - - - Bacterial sugar transferase
NEHPDDFL_02958 1.63e-57 - - - M - - - Glycosyltransferase like family 2
NEHPDDFL_02959 6.12e-74 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NEHPDDFL_02960 2.85e-69 - - - M - - - Glycosyltransferase, group 1 family protein
NEHPDDFL_02961 4.42e-09 - - - S ko:K19419 - ko00000,ko02000 EpsG family
NEHPDDFL_02962 3.24e-97 - - - S - - - Polysaccharide biosynthesis protein
NEHPDDFL_02963 2.28e-102 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHPDDFL_02964 1.29e-201 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEHPDDFL_02965 4.18e-24 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
NEHPDDFL_02966 3.34e-92 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
NEHPDDFL_02969 1.24e-11 - - - S - - - Immunity protein 22
NEHPDDFL_02970 4.15e-131 - - - S - - - ankyrin repeats
NEHPDDFL_02971 3.31e-52 - - - - - - - -
NEHPDDFL_02972 8.53e-28 - - - - - - - -
NEHPDDFL_02973 5.52e-64 - - - U - - - nuclease activity
NEHPDDFL_02974 2.05e-90 - - - - - - - -
NEHPDDFL_02975 5.12e-92 - - - S - - - Immunity protein 63
NEHPDDFL_02976 8.5e-55 - - - - - - - -
NEHPDDFL_02977 9.2e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
NEHPDDFL_02978 7.81e-263 - - - EGP - - - Transporter, major facilitator family protein
NEHPDDFL_02979 4.15e-188 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NEHPDDFL_02980 2.35e-212 - - - K - - - Transcriptional regulator
NEHPDDFL_02981 1.19e-191 - - - S - - - hydrolase
NEHPDDFL_02982 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NEHPDDFL_02983 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEHPDDFL_02984 1.15e-43 - - - - - - - -
NEHPDDFL_02985 6.24e-25 plnR - - - - - - -
NEHPDDFL_02986 9.76e-153 - - - - - - - -
NEHPDDFL_02987 3.29e-32 plnK - - - - - - -
NEHPDDFL_02988 8.53e-34 plnJ - - - - - - -
NEHPDDFL_02989 4.08e-39 - - - - - - - -
NEHPDDFL_02991 5.58e-291 - - - M - - - Glycosyl transferase family 2
NEHPDDFL_02992 2.08e-160 plnP - - S - - - CAAX protease self-immunity
NEHPDDFL_02993 1.22e-36 - - - - - - - -
NEHPDDFL_02994 1.9e-25 plnA - - - - - - -
NEHPDDFL_02995 2.08e-301 plnB 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NEHPDDFL_02996 4.11e-171 sppR - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEHPDDFL_02997 1.05e-173 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NEHPDDFL_02998 8.15e-167 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_02999 1.93e-31 plnF - - - - - - -
NEHPDDFL_03000 8.82e-32 - - - - - - - -
NEHPDDFL_03001 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEHPDDFL_03002 6.08e-309 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
NEHPDDFL_03003 7.79e-142 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_03004 5.04e-155 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_03005 2.75e-145 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_03006 7.34e-151 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NEHPDDFL_03007 4.23e-64 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
NEHPDDFL_03008 0.0 - - - L - - - DNA helicase
NEHPDDFL_03009 9.06e-185 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NEHPDDFL_03010 2.01e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEHPDDFL_03011 1.1e-165 - - - K - - - UbiC transcription regulator-associated domain protein
NEHPDDFL_03012 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_03013 9.68e-34 - - - - - - - -
NEHPDDFL_03014 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
NEHPDDFL_03015 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPDDFL_03016 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NEHPDDFL_03017 4.21e-210 - - - GK - - - ROK family
NEHPDDFL_03018 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
NEHPDDFL_03019 7.22e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEHPDDFL_03020 4.28e-263 - - - - - - - -
NEHPDDFL_03021 5.08e-194 - - - S - - - Psort location Cytoplasmic, score
NEHPDDFL_03022 2.35e-215 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NEHPDDFL_03023 9.68e-291 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NEHPDDFL_03024 4.65e-229 - - - - - - - -
NEHPDDFL_03025 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
NEHPDDFL_03026 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
NEHPDDFL_03027 1.14e-92 - - - F - - - DNA mismatch repair protein MutT
NEHPDDFL_03028 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEHPDDFL_03029 1.28e-273 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
NEHPDDFL_03030 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NEHPDDFL_03031 1.6e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NEHPDDFL_03032 1.06e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEHPDDFL_03033 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
NEHPDDFL_03034 2.26e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEHPDDFL_03035 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
NEHPDDFL_03036 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NEHPDDFL_03037 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
NEHPDDFL_03038 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NEHPDDFL_03039 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEHPDDFL_03040 2.82e-196 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NEHPDDFL_03041 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEHPDDFL_03042 2.82e-236 - - - S - - - DUF218 domain
NEHPDDFL_03043 4.31e-179 - - - - - - - -
NEHPDDFL_03044 7.18e-192 yxeH - - S - - - hydrolase
NEHPDDFL_03045 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
NEHPDDFL_03046 8.97e-200 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
NEHPDDFL_03047 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
NEHPDDFL_03048 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NEHPDDFL_03049 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEHPDDFL_03050 8.29e-312 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEHPDDFL_03051 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
NEHPDDFL_03052 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NEHPDDFL_03053 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NEHPDDFL_03054 6.59e-170 - - - S - - - YheO-like PAS domain
NEHPDDFL_03055 2.41e-37 - - - - - - - -
NEHPDDFL_03056 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEHPDDFL_03057 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEHPDDFL_03058 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NEHPDDFL_03059 2.57e-274 - - - J - - - translation release factor activity
NEHPDDFL_03060 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NEHPDDFL_03061 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
NEHPDDFL_03062 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NEHPDDFL_03063 1.84e-189 - - - - - - - -
NEHPDDFL_03064 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEHPDDFL_03065 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NEHPDDFL_03066 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEHPDDFL_03067 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEHPDDFL_03068 4.28e-84 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NEHPDDFL_03069 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
NEHPDDFL_03070 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NEHPDDFL_03071 3.55e-258 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NEHPDDFL_03072 8.87e-245 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NEHPDDFL_03073 3.39e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NEHPDDFL_03074 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NEHPDDFL_03075 1.39e-279 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
NEHPDDFL_03076 4.75e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEHPDDFL_03077 1.3e-110 queT - - S - - - QueT transporter
NEHPDDFL_03078 4.87e-148 - - - S - - - (CBS) domain
NEHPDDFL_03079 0.0 - - - S - - - Putative peptidoglycan binding domain
NEHPDDFL_03080 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NEHPDDFL_03081 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEHPDDFL_03082 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEHPDDFL_03083 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NEHPDDFL_03084 7.72e-57 yabO - - J - - - S4 domain protein
NEHPDDFL_03086 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NEHPDDFL_03087 1.69e-100 yabR - - J ko:K07571 - ko00000 RNA binding
NEHPDDFL_03088 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEHPDDFL_03089 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NEHPDDFL_03090 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEHPDDFL_03091 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NEHPDDFL_03092 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEHPDDFL_03093 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NEHPDDFL_03094 8.57e-41 - - - - - - - -
NEHPDDFL_03095 1.12e-246 ampC - - V - - - Beta-lactamase
NEHPDDFL_03096 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NEHPDDFL_03097 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
NEHPDDFL_03098 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
NEHPDDFL_03099 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NEHPDDFL_03100 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEHPDDFL_03101 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEHPDDFL_03102 4.39e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NEHPDDFL_03103 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEHPDDFL_03104 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEHPDDFL_03105 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NEHPDDFL_03106 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NEHPDDFL_03107 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEHPDDFL_03108 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEHPDDFL_03109 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEHPDDFL_03110 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEHPDDFL_03111 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEHPDDFL_03112 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEHPDDFL_03113 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NEHPDDFL_03114 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEHPDDFL_03115 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NEHPDDFL_03116 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NEHPDDFL_03117 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NEHPDDFL_03118 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
NEHPDDFL_03119 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NEHPDDFL_03120 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
NEHPDDFL_03121 5.28e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEHPDDFL_03122 4.95e-150 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NEHPDDFL_03123 3.03e-191 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NEHPDDFL_03124 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NEHPDDFL_03125 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
NEHPDDFL_03126 2.53e-240 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NEHPDDFL_03127 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NEHPDDFL_03128 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NEHPDDFL_03129 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
NEHPDDFL_03130 6.65e-260 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
NEHPDDFL_03131 2.37e-107 uspA - - T - - - universal stress protein
NEHPDDFL_03132 1.34e-52 - - - - - - - -
NEHPDDFL_03133 4.2e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NEHPDDFL_03134 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NEHPDDFL_03135 5.51e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPDDFL_03136 1.57e-142 - - - S - - - Protein of unknown function (DUF1648)
NEHPDDFL_03137 1.2e-106 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NEHPDDFL_03138 3.73e-150 yktB - - S - - - Belongs to the UPF0637 family
NEHPDDFL_03139 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEHPDDFL_03140 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NEHPDDFL_03141 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NEHPDDFL_03142 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NEHPDDFL_03143 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NEHPDDFL_03144 5.71e-302 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
NEHPDDFL_03145 2.92e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NEHPDDFL_03146 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEHPDDFL_03147 5.62e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NEHPDDFL_03148 1.35e-149 radC - - L ko:K03630 - ko00000 DNA repair protein
NEHPDDFL_03149 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NEHPDDFL_03150 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NEHPDDFL_03151 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NEHPDDFL_03152 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NEHPDDFL_03153 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NEHPDDFL_03154 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NEHPDDFL_03155 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEHPDDFL_03156 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NEHPDDFL_03157 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NEHPDDFL_03158 7.16e-296 ymfF - - S - - - Peptidase M16 inactive domain protein
NEHPDDFL_03159 0.0 ymfH - - S - - - Peptidase M16
NEHPDDFL_03160 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
NEHPDDFL_03161 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEHPDDFL_03162 1.56e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NEHPDDFL_03163 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEHPDDFL_03164 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NEHPDDFL_03165 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
NEHPDDFL_03166 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEHPDDFL_03167 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEHPDDFL_03168 1.35e-93 - - - - - - - -
NEHPDDFL_03169 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NEHPDDFL_03170 1.25e-119 - - - - - - - -
NEHPDDFL_03171 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEHPDDFL_03172 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEHPDDFL_03173 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NEHPDDFL_03174 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEHPDDFL_03175 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NEHPDDFL_03176 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEHPDDFL_03177 4.12e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NEHPDDFL_03178 1.86e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NEHPDDFL_03179 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEHPDDFL_03180 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
NEHPDDFL_03181 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEHPDDFL_03182 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
NEHPDDFL_03183 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NEHPDDFL_03184 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEHPDDFL_03185 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NEHPDDFL_03186 2.57e-118 yslB - - S - - - Protein of unknown function (DUF2507)
NEHPDDFL_03187 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NEHPDDFL_03188 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEHPDDFL_03189 4.53e-122 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NEHPDDFL_03190 7.94e-114 ykuL - - S - - - (CBS) domain
NEHPDDFL_03191 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NEHPDDFL_03192 5.09e-286 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NEHPDDFL_03193 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NEHPDDFL_03194 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NEHPDDFL_03195 6.52e-96 - - - - - - - -
NEHPDDFL_03196 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
NEHPDDFL_03197 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NEHPDDFL_03198 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NEHPDDFL_03199 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
NEHPDDFL_03200 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
NEHPDDFL_03201 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
NEHPDDFL_03202 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEHPDDFL_03203 1.55e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NEHPDDFL_03204 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NEHPDDFL_03205 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
NEHPDDFL_03206 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
NEHPDDFL_03207 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
NEHPDDFL_03208 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
NEHPDDFL_03210 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NEHPDDFL_03211 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEHPDDFL_03212 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NEHPDDFL_03213 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
NEHPDDFL_03214 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NEHPDDFL_03215 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
NEHPDDFL_03216 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NEHPDDFL_03217 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
NEHPDDFL_03218 2.92e-152 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NEHPDDFL_03219 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEHPDDFL_03220 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
NEHPDDFL_03221 4.51e-84 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)