ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MDCBHCFC_00001 1.44e-30 - - - S - - - P2 phage tail completion protein R (GpR)
MDCBHCFC_00002 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
MDCBHCFC_00003 4.36e-181 lacI - - K - - - binds specific sites in lac operon resulting in DNA looping between the operators
MDCBHCFC_00004 2.8e-63 tetA - - EGP ko:K08151,ko:K08153 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
MDCBHCFC_00036 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MDCBHCFC_00037 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MDCBHCFC_00038 2.15e-237 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
MDCBHCFC_00039 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MDCBHCFC_00040 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MDCBHCFC_00041 1.9e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
MDCBHCFC_00042 1.29e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
MDCBHCFC_00043 6.82e-274 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
MDCBHCFC_00044 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
MDCBHCFC_00046 6.86e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
MDCBHCFC_00047 5.85e-226 ytcB - - M - - - NAD-dependent epimerase dehydratase
MDCBHCFC_00048 2.27e-307 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDCBHCFC_00049 6.65e-194 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MDCBHCFC_00050 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
MDCBHCFC_00051 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MDCBHCFC_00052 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MDCBHCFC_00053 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MDCBHCFC_00054 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MDCBHCFC_00055 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MDCBHCFC_00056 4.09e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MDCBHCFC_00057 1.53e-216 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MDCBHCFC_00058 1.97e-175 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MDCBHCFC_00059 1.44e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MDCBHCFC_00060 8.09e-176 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MDCBHCFC_00061 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
MDCBHCFC_00062 9.47e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MDCBHCFC_00063 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MDCBHCFC_00064 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MDCBHCFC_00065 3.65e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MDCBHCFC_00066 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDCBHCFC_00067 4.78e-95 ytkA - - S - - - YtkA-like
MDCBHCFC_00069 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MDCBHCFC_00070 3.2e-81 ytkC - - S - - - Bacteriophage holin family
MDCBHCFC_00071 1.82e-112 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MDCBHCFC_00072 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MDCBHCFC_00073 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MDCBHCFC_00074 1.87e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MDCBHCFC_00075 3.86e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MDCBHCFC_00076 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
MDCBHCFC_00077 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MDCBHCFC_00078 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDCBHCFC_00079 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MDCBHCFC_00080 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MDCBHCFC_00081 3.4e-87 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MDCBHCFC_00082 2.72e-191 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
MDCBHCFC_00083 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
MDCBHCFC_00084 1.17e-133 ytqB - - J - - - Putative rRNA methylase
MDCBHCFC_00085 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
MDCBHCFC_00086 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
MDCBHCFC_00088 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
MDCBHCFC_00089 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_00090 4.18e-216 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MDCBHCFC_00091 2.26e-191 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
MDCBHCFC_00092 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_00093 1.39e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MDCBHCFC_00094 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_00095 1.39e-233 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
MDCBHCFC_00096 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_00097 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
MDCBHCFC_00098 9.37e-77 yttA - - S - - - Pfam Transposase IS66
MDCBHCFC_00099 8.54e-269 yttB - - EGP - - - Major facilitator superfamily
MDCBHCFC_00100 1.56e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MDCBHCFC_00101 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
MDCBHCFC_00102 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MDCBHCFC_00103 1.22e-68 ytwF - - P - - - Sulfurtransferase
MDCBHCFC_00104 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MDCBHCFC_00105 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MDCBHCFC_00106 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDCBHCFC_00107 1.22e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDCBHCFC_00108 4.56e-244 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_00109 3.94e-220 - - - S - - - Acetyl xylan esterase (AXE1)
MDCBHCFC_00110 2.24e-179 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MDCBHCFC_00111 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MDCBHCFC_00112 9.01e-276 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MDCBHCFC_00113 9.36e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MDCBHCFC_00114 6.48e-244 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MDCBHCFC_00115 5.47e-280 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MDCBHCFC_00116 1.82e-177 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
MDCBHCFC_00117 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MDCBHCFC_00118 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MDCBHCFC_00119 0.0 ytdP - - K - - - Transcriptional regulator
MDCBHCFC_00120 2.65e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
MDCBHCFC_00121 3.24e-276 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MDCBHCFC_00122 6.78e-94 yteS - - G - - - transport
MDCBHCFC_00123 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
MDCBHCFC_00124 3.81e-150 yteU - - S - - - Integral membrane protein
MDCBHCFC_00125 2.14e-36 yteV - - S - - - Sporulation protein Cse60
MDCBHCFC_00126 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
MDCBHCFC_00127 1.41e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
MDCBHCFC_00128 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDCBHCFC_00129 2.13e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MDCBHCFC_00130 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
MDCBHCFC_00131 9.39e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MDCBHCFC_00132 7.09e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
MDCBHCFC_00133 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
MDCBHCFC_00134 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
MDCBHCFC_00135 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MDCBHCFC_00136 1.01e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MDCBHCFC_00137 4.92e-212 ytlQ - - - - - - -
MDCBHCFC_00138 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MDCBHCFC_00139 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MDCBHCFC_00140 3.02e-192 ytmP - - M - - - Phosphotransferase
MDCBHCFC_00141 7.83e-60 ytzH - - S - - - YtzH-like protein
MDCBHCFC_00142 2.16e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDCBHCFC_00143 1.06e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MDCBHCFC_00144 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MDCBHCFC_00145 1.17e-67 ytzB - - S - - - small secreted protein
MDCBHCFC_00146 2.15e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
MDCBHCFC_00147 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
MDCBHCFC_00148 3.17e-75 ytpP - - CO - - - Thioredoxin
MDCBHCFC_00149 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
MDCBHCFC_00150 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDCBHCFC_00151 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MDCBHCFC_00152 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MDCBHCFC_00153 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDCBHCFC_00154 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
MDCBHCFC_00155 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
MDCBHCFC_00156 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MDCBHCFC_00157 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MDCBHCFC_00158 1.96e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MDCBHCFC_00159 1.31e-160 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MDCBHCFC_00160 2.12e-289 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
MDCBHCFC_00161 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MDCBHCFC_00162 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MDCBHCFC_00163 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MDCBHCFC_00164 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDCBHCFC_00166 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDCBHCFC_00167 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
MDCBHCFC_00168 3.24e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MDCBHCFC_00169 1.2e-141 yttP - - K - - - Transcriptional regulator
MDCBHCFC_00170 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MDCBHCFC_00171 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDCBHCFC_00172 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MDCBHCFC_00173 1.3e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MDCBHCFC_00174 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDCBHCFC_00175 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
MDCBHCFC_00176 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MDCBHCFC_00177 0.0 ytcJ - - S - - - amidohydrolase
MDCBHCFC_00178 2.4e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDCBHCFC_00179 8.34e-231 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
MDCBHCFC_00180 1.37e-110 yteJ - - S - - - RDD family
MDCBHCFC_00181 8.34e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
MDCBHCFC_00182 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
MDCBHCFC_00183 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDCBHCFC_00184 1.26e-222 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MDCBHCFC_00185 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDCBHCFC_00186 9.5e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
MDCBHCFC_00187 4.3e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDCBHCFC_00188 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MDCBHCFC_00190 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_00191 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
MDCBHCFC_00192 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
MDCBHCFC_00193 2.15e-63 ytpI - - S - - - YtpI-like protein
MDCBHCFC_00194 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
MDCBHCFC_00195 1.15e-39 - - - - - - - -
MDCBHCFC_00196 5.12e-112 ytrI - - - - - - -
MDCBHCFC_00197 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
MDCBHCFC_00198 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MDCBHCFC_00199 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
MDCBHCFC_00200 1.25e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MDCBHCFC_00201 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MDCBHCFC_00202 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDCBHCFC_00203 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MDCBHCFC_00204 3.7e-79 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
MDCBHCFC_00205 7.83e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
MDCBHCFC_00206 9.38e-95 ytwI - - S - - - membrane
MDCBHCFC_00207 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MDCBHCFC_00208 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
MDCBHCFC_00209 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
MDCBHCFC_00210 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_00211 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
MDCBHCFC_00212 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDCBHCFC_00213 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDCBHCFC_00214 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
MDCBHCFC_00215 1.15e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDCBHCFC_00216 1.3e-204 ytbE - - S - - - reductase
MDCBHCFC_00217 1.28e-258 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
MDCBHCFC_00218 1.15e-86 ytcD - - K - - - Transcriptional regulator
MDCBHCFC_00219 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDCBHCFC_00220 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MDCBHCFC_00221 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDCBHCFC_00222 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
MDCBHCFC_00223 2.46e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MDCBHCFC_00224 3.82e-141 ytxB - - S - - - SNARE associated Golgi protein
MDCBHCFC_00225 5.74e-204 ytxC - - S - - - YtxC-like family
MDCBHCFC_00227 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDCBHCFC_00228 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MDCBHCFC_00229 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_00230 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
MDCBHCFC_00231 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MDCBHCFC_00232 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MDCBHCFC_00234 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDCBHCFC_00235 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MDCBHCFC_00236 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDCBHCFC_00237 1.27e-59 ysdA - - S - - - Membrane
MDCBHCFC_00238 9.34e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
MDCBHCFC_00239 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
MDCBHCFC_00240 1.16e-240 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MDCBHCFC_00241 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MDCBHCFC_00242 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
MDCBHCFC_00243 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MDCBHCFC_00244 5.81e-185 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
MDCBHCFC_00245 2.62e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MDCBHCFC_00246 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MDCBHCFC_00247 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
MDCBHCFC_00248 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
MDCBHCFC_00249 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
MDCBHCFC_00250 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
MDCBHCFC_00251 2.41e-68 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
MDCBHCFC_00252 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
MDCBHCFC_00253 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
MDCBHCFC_00254 1.02e-259 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
MDCBHCFC_00255 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
MDCBHCFC_00256 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDCBHCFC_00257 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDCBHCFC_00258 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDCBHCFC_00259 1.41e-213 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDCBHCFC_00260 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MDCBHCFC_00261 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
MDCBHCFC_00262 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
MDCBHCFC_00263 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDCBHCFC_00264 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
MDCBHCFC_00265 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MDCBHCFC_00266 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_00267 3.12e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
MDCBHCFC_00268 3.01e-178 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
MDCBHCFC_00269 1.43e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
MDCBHCFC_00271 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
MDCBHCFC_00272 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MDCBHCFC_00273 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDCBHCFC_00274 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MDCBHCFC_00275 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
MDCBHCFC_00276 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
MDCBHCFC_00277 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MDCBHCFC_00278 2.33e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
MDCBHCFC_00279 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
MDCBHCFC_00280 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_00281 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDCBHCFC_00282 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MDCBHCFC_00283 1.14e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
MDCBHCFC_00284 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MDCBHCFC_00285 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDCBHCFC_00286 1.65e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MDCBHCFC_00288 9.64e-183 ysnF - - S - - - protein conserved in bacteria
MDCBHCFC_00289 1.71e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
MDCBHCFC_00291 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MDCBHCFC_00292 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
MDCBHCFC_00293 5.55e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MDCBHCFC_00294 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MDCBHCFC_00295 1.75e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MDCBHCFC_00296 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDCBHCFC_00297 2.98e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MDCBHCFC_00298 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
MDCBHCFC_00299 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDCBHCFC_00300 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDCBHCFC_00301 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
MDCBHCFC_00302 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MDCBHCFC_00303 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MDCBHCFC_00304 4.77e-116 ysxD - - - - - - -
MDCBHCFC_00305 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MDCBHCFC_00306 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
MDCBHCFC_00307 8.91e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MDCBHCFC_00308 4.13e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MDCBHCFC_00309 1.06e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
MDCBHCFC_00310 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MDCBHCFC_00311 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
MDCBHCFC_00312 2.79e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MDCBHCFC_00313 1.53e-35 - - - - - - - -
MDCBHCFC_00314 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDCBHCFC_00315 1.55e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MDCBHCFC_00316 5.2e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MDCBHCFC_00317 4.28e-211 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
MDCBHCFC_00318 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
MDCBHCFC_00319 3.97e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MDCBHCFC_00320 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
MDCBHCFC_00321 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MDCBHCFC_00322 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
MDCBHCFC_00323 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MDCBHCFC_00324 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MDCBHCFC_00325 5.24e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MDCBHCFC_00326 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
MDCBHCFC_00327 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MDCBHCFC_00328 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
MDCBHCFC_00329 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MDCBHCFC_00330 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
MDCBHCFC_00331 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDCBHCFC_00332 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MDCBHCFC_00333 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MDCBHCFC_00334 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
MDCBHCFC_00335 7.9e-289 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MDCBHCFC_00336 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MDCBHCFC_00337 2.41e-200 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
MDCBHCFC_00338 2.66e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MDCBHCFC_00339 2.43e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
MDCBHCFC_00340 2.55e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDCBHCFC_00341 1.01e-163 yebC - - K - - - transcriptional regulatory protein
MDCBHCFC_00342 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
MDCBHCFC_00343 6.33e-68 - - - S - - - Family of unknown function (DUF5412)
MDCBHCFC_00345 1.91e-151 yrzF - - T - - - serine threonine protein kinase
MDCBHCFC_00346 2.77e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
MDCBHCFC_00347 0.0 csbX - - EGP - - - the major facilitator superfamily
MDCBHCFC_00348 1.85e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
MDCBHCFC_00349 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDCBHCFC_00350 5.29e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDCBHCFC_00351 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
MDCBHCFC_00352 1.73e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MDCBHCFC_00353 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MDCBHCFC_00354 1.24e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
MDCBHCFC_00355 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
MDCBHCFC_00356 4.1e-143 yrbG - - S - - - membrane
MDCBHCFC_00357 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDCBHCFC_00358 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
MDCBHCFC_00359 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MDCBHCFC_00360 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MDCBHCFC_00361 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
MDCBHCFC_00362 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MDCBHCFC_00363 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDCBHCFC_00364 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDCBHCFC_00365 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDCBHCFC_00366 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
MDCBHCFC_00368 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MDCBHCFC_00369 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MDCBHCFC_00370 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MDCBHCFC_00371 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MDCBHCFC_00372 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_00373 7.33e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
MDCBHCFC_00374 4.64e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDCBHCFC_00375 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
MDCBHCFC_00376 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDCBHCFC_00377 1.44e-107 yrrD - - S - - - protein conserved in bacteria
MDCBHCFC_00378 8.4e-42 yrzR - - - - - - -
MDCBHCFC_00379 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
MDCBHCFC_00380 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDCBHCFC_00381 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDCBHCFC_00382 1.67e-183 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MDCBHCFC_00383 8.99e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MDCBHCFC_00384 3.07e-242 yrrI - - S - - - AI-2E family transporter
MDCBHCFC_00385 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDCBHCFC_00386 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
MDCBHCFC_00387 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDCBHCFC_00388 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
MDCBHCFC_00389 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDCBHCFC_00390 1.98e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
MDCBHCFC_00391 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
MDCBHCFC_00392 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
MDCBHCFC_00393 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MDCBHCFC_00394 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDCBHCFC_00395 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
MDCBHCFC_00396 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
MDCBHCFC_00397 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
MDCBHCFC_00398 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
MDCBHCFC_00399 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDCBHCFC_00400 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
MDCBHCFC_00401 2.45e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MDCBHCFC_00402 6.93e-49 yrhC - - S - - - YrhC-like protein
MDCBHCFC_00403 1.73e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
MDCBHCFC_00404 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
MDCBHCFC_00405 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
MDCBHCFC_00406 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
MDCBHCFC_00408 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
MDCBHCFC_00409 1.18e-121 yrhH - - Q - - - methyltransferase
MDCBHCFC_00410 6.49e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MDCBHCFC_00411 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MDCBHCFC_00412 6.32e-59 yrhK - - S - - - YrhK-like protein
MDCBHCFC_00413 0.0 oatA - - I - - - Acyltransferase family
MDCBHCFC_00414 2.88e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
MDCBHCFC_00415 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_00416 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
MDCBHCFC_00417 5.63e-137 yrhP - - E - - - LysE type translocator
MDCBHCFC_00418 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MDCBHCFC_00419 0.0 levR - - K - - - PTS system fructose IIA component
MDCBHCFC_00420 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MDCBHCFC_00421 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
MDCBHCFC_00422 2.79e-166 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MDCBHCFC_00423 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MDCBHCFC_00424 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MDCBHCFC_00425 3.2e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MDCBHCFC_00426 3.79e-250 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
MDCBHCFC_00427 4.53e-33 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
MDCBHCFC_00428 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MDCBHCFC_00429 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
MDCBHCFC_00430 1.23e-35 yraE - - - ko:K06440 - ko00000 -
MDCBHCFC_00431 3.41e-279 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MDCBHCFC_00432 9.61e-84 yraF - - M - - - Spore coat protein
MDCBHCFC_00433 4.19e-50 yraG - - - ko:K06440 - ko00000 -
MDCBHCFC_00434 6.62e-87 - - - E - - - Glyoxalase-like domain
MDCBHCFC_00435 2.92e-81 - - - T - - - sh3 domain protein
MDCBHCFC_00436 1.33e-79 - - - T - - - sh3 domain protein
MDCBHCFC_00437 5.9e-192 - - - S - - - Alpha beta hydrolase
MDCBHCFC_00438 5.07e-56 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDCBHCFC_00439 2.57e-192 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MDCBHCFC_00440 1.15e-237 yrpG - - C - - - Aldo/keto reductase family
MDCBHCFC_00441 1.24e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_00442 7.31e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MDCBHCFC_00443 1.51e-85 napB - - K - - - MarR family transcriptional regulator
MDCBHCFC_00444 3.18e-279 yfjF - - EGP - - - Belongs to the major facilitator superfamily
MDCBHCFC_00446 2.22e-175 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
MDCBHCFC_00447 6.83e-191 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
MDCBHCFC_00448 1.7e-145 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_00449 1.94e-266 - - - P - - - Major Facilitator Superfamily
MDCBHCFC_00451 2.34e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MDCBHCFC_00452 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
MDCBHCFC_00453 9.38e-186 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MDCBHCFC_00454 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MDCBHCFC_00455 1.04e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
MDCBHCFC_00456 2.01e-118 yrdA - - S - - - DinB family
MDCBHCFC_00457 1.04e-71 - - - S - - - Protein of unknown function (DUF2568)
MDCBHCFC_00458 2.11e-130 yrdC - - Q - - - Isochorismatase family
MDCBHCFC_00459 8.91e-289 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MDCBHCFC_00460 7.91e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
MDCBHCFC_00461 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
MDCBHCFC_00462 6.57e-176 azlC - - E - - - AzlC protein
MDCBHCFC_00463 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
MDCBHCFC_00464 2.03e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MDCBHCFC_00466 6e-213 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
MDCBHCFC_00467 5e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
MDCBHCFC_00468 1.4e-203 - - - K - - - Transcriptional regulator
MDCBHCFC_00469 4.03e-215 yrdR - - EG - - - EamA-like transporter family
MDCBHCFC_00470 7.04e-23 - - - S - - - YrzO-like protein
MDCBHCFC_00471 3.27e-294 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MDCBHCFC_00472 2.16e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
MDCBHCFC_00473 1.47e-266 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_00474 3.56e-194 bltR - - K - - - helix_turn_helix, mercury resistance
MDCBHCFC_00475 7.4e-137 yrkC - - G - - - Cupin domain
MDCBHCFC_00476 3.32e-28 - - - - - - - -
MDCBHCFC_00477 4.38e-52 yrkD - - S - - - protein conserved in bacteria
MDCBHCFC_00478 1.61e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
MDCBHCFC_00479 2.04e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
MDCBHCFC_00480 7.04e-271 yrkH - - P - - - Rhodanese Homology Domain
MDCBHCFC_00481 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
MDCBHCFC_00482 1.29e-165 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
MDCBHCFC_00483 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
MDCBHCFC_00484 3.31e-125 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
MDCBHCFC_00485 3.13e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
MDCBHCFC_00486 1.02e-280 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
MDCBHCFC_00487 8.35e-163 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
MDCBHCFC_00488 9.96e-304 yrkQ - - T - - - Histidine kinase
MDCBHCFC_00489 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
MDCBHCFC_00490 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDCBHCFC_00491 2.16e-120 xkdA - - E - - - IrrE N-terminal-like domain
MDCBHCFC_00493 1.25e-74 - - - K - - - sequence-specific DNA binding
MDCBHCFC_00494 5.48e-48 - - - K - - - Helix-turn-helix XRE-family like proteins
MDCBHCFC_00496 3.5e-132 - - - - - - - -
MDCBHCFC_00500 1.08e-218 yqaJ - - L - - - YqaJ-like viral recombinase domain
MDCBHCFC_00501 3.25e-191 recT - - L ko:K07455 - ko00000,ko03400 RecT family
MDCBHCFC_00502 3.06e-155 yqaL - - L - - - DnaD domain protein
MDCBHCFC_00503 1.02e-206 yqaM - - L - - - IstB-like ATP binding protein
MDCBHCFC_00505 7.11e-91 rusA - - L - - - Endodeoxyribonuclease RusA
MDCBHCFC_00506 1.24e-41 yqaO - - S - - - Phage-like element PBSX protein XtrA
MDCBHCFC_00509 8.46e-101 yqaQ - - L - - - Transposase
MDCBHCFC_00511 1.1e-146 yqaS - - L - - - DNA packaging
MDCBHCFC_00512 4.64e-313 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
MDCBHCFC_00513 0.0 yqbA - - S - - - portal protein
MDCBHCFC_00514 7.59e-196 - - - S - - - Phage Mu protein F like protein
MDCBHCFC_00515 5.03e-90 - - - S - - - Phage Mu protein F like protein
MDCBHCFC_00516 6.01e-158 yqbD - - L - - - Putative phage serine protease XkdF
MDCBHCFC_00517 1.07e-214 xkdG - - S - - - Phage capsid family
MDCBHCFC_00518 9.75e-51 - - - S - - - YqbF, hypothetical protein domain
MDCBHCFC_00519 6.81e-86 - - - S - - - Protein of unknown function (DUF3199)
MDCBHCFC_00520 9.68e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
MDCBHCFC_00521 2.18e-122 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MDCBHCFC_00522 6.29e-100 yqbJ - - - - - - -
MDCBHCFC_00523 4.2e-35 - - - - - - - -
MDCBHCFC_00524 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
MDCBHCFC_00525 4.23e-99 xkdM - - S - - - Phage tail tube protein
MDCBHCFC_00527 1.58e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MDCBHCFC_00528 0.0 xkdO - - L - - - Transglycosylase SLT domain
MDCBHCFC_00529 9.43e-154 xkdP - - S - - - Lysin motif
MDCBHCFC_00530 2.57e-225 xkdQ - - G - - - NLP P60 protein
MDCBHCFC_00531 5.52e-49 xkdR - - S - - - Protein of unknown function (DUF2577)
MDCBHCFC_00532 1.33e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
MDCBHCFC_00533 1.57e-237 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MDCBHCFC_00534 2.74e-126 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MDCBHCFC_00535 1.61e-49 - - - - - - - -
MDCBHCFC_00536 2.96e-246 - - - - - - - -
MDCBHCFC_00537 1.38e-71 xkdW - - S - - - XkdW protein
MDCBHCFC_00538 2.51e-28 - - - - - - - -
MDCBHCFC_00539 1.36e-210 xepA - - - - - - -
MDCBHCFC_00540 1.19e-88 - - - S - - - Bacteriophage holin family
MDCBHCFC_00541 4.44e-167 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MDCBHCFC_00543 5.4e-80 - - - - - - - -
MDCBHCFC_00545 5.39e-285 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MDCBHCFC_00548 6.01e-115 - - - S - - - Tetratricopeptide repeat
MDCBHCFC_00549 4.73e-62 - - - Q - - - Collagen triple helix repeat (20 copies)
MDCBHCFC_00550 1.36e-119 - - - M - - - Glycosyltransferase like family
MDCBHCFC_00551 1.31e-152 - - - H - - - Methionine biosynthesis protein MetW
MDCBHCFC_00552 5.82e-246 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MDCBHCFC_00553 8.04e-275 - - - H - - - N-terminal domain of galactosyltransferase
MDCBHCFC_00554 0.0 - - - L ko:K06400 - ko00000 Recombinase
MDCBHCFC_00555 1.01e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDCBHCFC_00556 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
MDCBHCFC_00557 1.49e-167 - - - - - - - -
MDCBHCFC_00558 3.62e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
MDCBHCFC_00559 1.09e-133 yqeD - - S - - - SNARE associated Golgi protein
MDCBHCFC_00560 5.03e-178 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MDCBHCFC_00561 9.11e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
MDCBHCFC_00563 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
MDCBHCFC_00564 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MDCBHCFC_00565 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MDCBHCFC_00566 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
MDCBHCFC_00567 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDCBHCFC_00568 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
MDCBHCFC_00569 1.39e-81 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDCBHCFC_00570 5.67e-178 yqeM - - Q - - - Methyltransferase
MDCBHCFC_00571 4.46e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDCBHCFC_00572 1.5e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
MDCBHCFC_00573 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MDCBHCFC_00574 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MDCBHCFC_00575 2.36e-22 - - - S - - - YqzM-like protein
MDCBHCFC_00576 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MDCBHCFC_00577 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MDCBHCFC_00578 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MDCBHCFC_00579 5.51e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
MDCBHCFC_00580 6.79e-68 yqxA - - S - - - Protein of unknown function (DUF3679)
MDCBHCFC_00581 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDCBHCFC_00582 1.13e-273 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MDCBHCFC_00583 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDCBHCFC_00584 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDCBHCFC_00585 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MDCBHCFC_00586 3.97e-256 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDCBHCFC_00587 1.33e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
MDCBHCFC_00588 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MDCBHCFC_00589 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
MDCBHCFC_00590 4.02e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
MDCBHCFC_00591 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MDCBHCFC_00592 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
MDCBHCFC_00593 2.18e-289 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
MDCBHCFC_00594 4.35e-192 yqfA - - S - - - UPF0365 protein
MDCBHCFC_00595 2.57e-78 yqfB - - - - - - -
MDCBHCFC_00596 2.07e-60 yqfC - - S - - - sporulation protein YqfC
MDCBHCFC_00597 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
MDCBHCFC_00598 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
MDCBHCFC_00600 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
MDCBHCFC_00601 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDCBHCFC_00602 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MDCBHCFC_00603 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MDCBHCFC_00604 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDCBHCFC_00605 5.29e-27 - - - S - - - YqzL-like protein
MDCBHCFC_00606 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MDCBHCFC_00607 2.47e-221 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MDCBHCFC_00608 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MDCBHCFC_00609 2.31e-144 ccpN - - K - - - CBS domain
MDCBHCFC_00610 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDCBHCFC_00611 4.96e-113 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
MDCBHCFC_00612 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDCBHCFC_00613 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDCBHCFC_00614 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MDCBHCFC_00615 9.4e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MDCBHCFC_00616 2.54e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDCBHCFC_00617 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MDCBHCFC_00618 1.05e-48 yqfQ - - S - - - YqfQ-like protein
MDCBHCFC_00619 2.21e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDCBHCFC_00620 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MDCBHCFC_00621 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
MDCBHCFC_00622 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MDCBHCFC_00623 4.98e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
MDCBHCFC_00624 5.58e-140 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
MDCBHCFC_00625 2.04e-81 yqfX - - S - - - membrane
MDCBHCFC_00626 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MDCBHCFC_00627 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
MDCBHCFC_00628 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
MDCBHCFC_00629 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
MDCBHCFC_00630 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
MDCBHCFC_00631 1.61e-292 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
MDCBHCFC_00632 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
MDCBHCFC_00633 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MDCBHCFC_00634 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MDCBHCFC_00635 1.76e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
MDCBHCFC_00636 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDCBHCFC_00637 6.37e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDCBHCFC_00638 1.09e-93 yqzC - - S - - - YceG-like family
MDCBHCFC_00639 3.42e-68 yqzD - - - - - - -
MDCBHCFC_00641 7.92e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
MDCBHCFC_00642 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MDCBHCFC_00643 3.25e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDCBHCFC_00644 3.38e-14 yqgO - - - - - - -
MDCBHCFC_00645 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
MDCBHCFC_00646 1.27e-43 yqgQ - - S - - - Protein conserved in bacteria
MDCBHCFC_00647 2.31e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MDCBHCFC_00648 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MDCBHCFC_00649 1.69e-280 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
MDCBHCFC_00650 3.82e-256 yqgU - - - - - - -
MDCBHCFC_00651 7.34e-66 yqgV - - S - - - Thiamine-binding protein
MDCBHCFC_00652 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
MDCBHCFC_00653 7.54e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
MDCBHCFC_00654 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
MDCBHCFC_00655 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
MDCBHCFC_00657 8.33e-191 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDCBHCFC_00658 4.95e-306 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MDCBHCFC_00659 8.37e-231 yqxL - - P - - - Mg2 transporter protein
MDCBHCFC_00660 7.5e-06 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
MDCBHCFC_00661 5.23e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MDCBHCFC_00662 2.5e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
MDCBHCFC_00663 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
MDCBHCFC_00664 5.81e-86 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
MDCBHCFC_00665 1.77e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
MDCBHCFC_00666 7.11e-47 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MDCBHCFC_00667 1.88e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
MDCBHCFC_00668 4.9e-37 yqzE - - S - - - YqzE-like protein
MDCBHCFC_00669 1.24e-68 yqzG - - S - - - Protein of unknown function (DUF3889)
MDCBHCFC_00670 1.04e-151 yqxM - - - ko:K19433 - ko00000 -
MDCBHCFC_00671 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
MDCBHCFC_00672 3.14e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
MDCBHCFC_00673 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
MDCBHCFC_00674 1.39e-33 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
MDCBHCFC_00675 2.94e-193 yqhG - - S - - - Bacterial protein YqhG of unknown function
MDCBHCFC_00676 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MDCBHCFC_00677 3.31e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
MDCBHCFC_00678 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDCBHCFC_00679 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MDCBHCFC_00680 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
MDCBHCFC_00681 1.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MDCBHCFC_00682 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MDCBHCFC_00683 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MDCBHCFC_00684 5.18e-81 yqhP - - - - - - -
MDCBHCFC_00685 2.98e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
MDCBHCFC_00686 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
MDCBHCFC_00687 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
MDCBHCFC_00688 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MDCBHCFC_00689 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDCBHCFC_00690 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
MDCBHCFC_00691 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
MDCBHCFC_00692 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
MDCBHCFC_00693 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
MDCBHCFC_00694 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
MDCBHCFC_00695 2.19e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
MDCBHCFC_00696 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
MDCBHCFC_00697 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
MDCBHCFC_00698 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
MDCBHCFC_00699 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MDCBHCFC_00700 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MDCBHCFC_00701 1.65e-88 yqhY - - S - - - protein conserved in bacteria
MDCBHCFC_00702 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDCBHCFC_00703 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDCBHCFC_00704 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDCBHCFC_00705 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDCBHCFC_00706 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MDCBHCFC_00707 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDCBHCFC_00708 2.93e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
MDCBHCFC_00709 8.85e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MDCBHCFC_00710 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MDCBHCFC_00711 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
MDCBHCFC_00712 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MDCBHCFC_00714 5.68e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MDCBHCFC_00715 2.26e-37 - - - - - - - -
MDCBHCFC_00716 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
MDCBHCFC_00717 5.61e-167 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MDCBHCFC_00718 1.1e-278 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MDCBHCFC_00719 9.4e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
MDCBHCFC_00720 2.86e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
MDCBHCFC_00721 1.85e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MDCBHCFC_00722 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
MDCBHCFC_00723 1.07e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MDCBHCFC_00724 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
MDCBHCFC_00725 0.0 bkdR - - KT - - - Transcriptional regulator
MDCBHCFC_00726 6.35e-201 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
MDCBHCFC_00727 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MDCBHCFC_00728 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
MDCBHCFC_00729 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDCBHCFC_00730 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDCBHCFC_00731 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDCBHCFC_00732 2.54e-286 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDCBHCFC_00733 2.6e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
MDCBHCFC_00734 1.79e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_00735 2.35e-211 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MDCBHCFC_00736 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
MDCBHCFC_00737 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MDCBHCFC_00738 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MDCBHCFC_00739 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MDCBHCFC_00740 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MDCBHCFC_00741 2.82e-127 yqjB - - S - - - protein conserved in bacteria
MDCBHCFC_00743 2.22e-93 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
MDCBHCFC_00744 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MDCBHCFC_00745 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
MDCBHCFC_00746 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
MDCBHCFC_00747 1.71e-177 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDCBHCFC_00748 4.35e-32 yqzJ - - - - - - -
MDCBHCFC_00749 2.14e-298 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDCBHCFC_00750 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDCBHCFC_00751 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDCBHCFC_00752 3.64e-220 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDCBHCFC_00753 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MDCBHCFC_00754 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MDCBHCFC_00755 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MDCBHCFC_00756 0.0 rocB - - E - - - arginine degradation protein
MDCBHCFC_00757 4.62e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDCBHCFC_00758 5.43e-228 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MDCBHCFC_00759 1.97e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_00760 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MDCBHCFC_00761 1.56e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MDCBHCFC_00762 4.47e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDCBHCFC_00764 8.91e-289 yqjV - - G - - - Major Facilitator Superfamily
MDCBHCFC_00766 7.79e-302 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDCBHCFC_00767 9.27e-66 yqiX - - S - - - YolD-like protein
MDCBHCFC_00768 3.16e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
MDCBHCFC_00769 3.73e-77 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
MDCBHCFC_00770 6.52e-248 yqkA - - K - - - GrpB protein
MDCBHCFC_00771 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
MDCBHCFC_00772 9.23e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
MDCBHCFC_00773 3.79e-219 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MDCBHCFC_00774 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
MDCBHCFC_00775 1.04e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
MDCBHCFC_00776 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
MDCBHCFC_00777 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MDCBHCFC_00778 2.41e-279 yqxK - - L - - - DNA helicase
MDCBHCFC_00779 3.18e-77 ansR - - K - - - Transcriptional regulator
MDCBHCFC_00780 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
MDCBHCFC_00781 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
MDCBHCFC_00782 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MDCBHCFC_00783 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MDCBHCFC_00784 2.97e-41 yqkK - - - - - - -
MDCBHCFC_00785 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MDCBHCFC_00786 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MDCBHCFC_00787 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
MDCBHCFC_00788 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
MDCBHCFC_00789 2.28e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MDCBHCFC_00790 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MDCBHCFC_00791 9.65e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MDCBHCFC_00792 3e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
MDCBHCFC_00793 1.37e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MDCBHCFC_00794 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDCBHCFC_00795 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
MDCBHCFC_00796 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
MDCBHCFC_00797 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
MDCBHCFC_00798 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
MDCBHCFC_00799 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
MDCBHCFC_00800 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
MDCBHCFC_00801 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
MDCBHCFC_00802 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDCBHCFC_00803 8.93e-192 ypuA - - S - - - Secreted protein
MDCBHCFC_00804 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDCBHCFC_00806 6.74e-30 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
MDCBHCFC_00807 8e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MDCBHCFC_00808 5.98e-72 ypuD - - - - - - -
MDCBHCFC_00809 2.07e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MDCBHCFC_00810 4.14e-146 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MDCBHCFC_00811 5.16e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MDCBHCFC_00812 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDCBHCFC_00813 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDCBHCFC_00814 4.17e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
MDCBHCFC_00815 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDCBHCFC_00816 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDCBHCFC_00817 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
MDCBHCFC_00818 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MDCBHCFC_00819 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
MDCBHCFC_00820 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
MDCBHCFC_00821 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MDCBHCFC_00822 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MDCBHCFC_00823 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
MDCBHCFC_00824 1.1e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MDCBHCFC_00825 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_00826 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_00827 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_00828 5.59e-236 rsiX - - - - - - -
MDCBHCFC_00829 6.26e-170 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MDCBHCFC_00830 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDCBHCFC_00831 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDCBHCFC_00832 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
MDCBHCFC_00833 8.28e-251 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
MDCBHCFC_00834 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MDCBHCFC_00835 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
MDCBHCFC_00836 8.61e-143 ypbE - - M - - - Lysin motif
MDCBHCFC_00837 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
MDCBHCFC_00838 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MDCBHCFC_00839 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MDCBHCFC_00840 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MDCBHCFC_00841 4.25e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
MDCBHCFC_00842 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
MDCBHCFC_00843 6.93e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
MDCBHCFC_00844 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
MDCBHCFC_00845 1.27e-141 ypfA - - M - - - Flagellar protein YcgR
MDCBHCFC_00846 1.39e-29 - - - S - - - Family of unknown function (DUF5359)
MDCBHCFC_00847 7.9e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MDCBHCFC_00848 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MDCBHCFC_00849 1.1e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDCBHCFC_00850 1.13e-11 - - - S - - - YpzI-like protein
MDCBHCFC_00851 2.73e-134 yphA - - - - - - -
MDCBHCFC_00852 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
MDCBHCFC_00853 5.91e-38 ypzH - - - - - - -
MDCBHCFC_00854 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MDCBHCFC_00855 8.97e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MDCBHCFC_00856 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
MDCBHCFC_00857 2.5e-175 yphF - - - - - - -
MDCBHCFC_00858 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MDCBHCFC_00859 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDCBHCFC_00860 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MDCBHCFC_00861 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MDCBHCFC_00862 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MDCBHCFC_00863 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDCBHCFC_00864 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MDCBHCFC_00865 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MDCBHCFC_00866 2.49e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
MDCBHCFC_00867 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MDCBHCFC_00868 5.72e-263 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MDCBHCFC_00869 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MDCBHCFC_00870 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDCBHCFC_00871 5e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MDCBHCFC_00872 4.88e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MDCBHCFC_00873 1.57e-150 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MDCBHCFC_00874 3.64e-292 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MDCBHCFC_00875 1.82e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MDCBHCFC_00876 4.31e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MDCBHCFC_00877 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MDCBHCFC_00878 3.31e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MDCBHCFC_00879 7.18e-297 ypiA - - S - - - COG0457 FOG TPR repeat
MDCBHCFC_00880 7.45e-129 ypiB - - S - - - Belongs to the UPF0302 family
MDCBHCFC_00881 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
MDCBHCFC_00882 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
MDCBHCFC_00883 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
MDCBHCFC_00884 3.31e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
MDCBHCFC_00885 1.63e-125 ypjA - - S - - - membrane
MDCBHCFC_00886 2.79e-182 ypjB - - S - - - sporulation protein
MDCBHCFC_00887 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MDCBHCFC_00888 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
MDCBHCFC_00889 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDCBHCFC_00890 1.03e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
MDCBHCFC_00891 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
MDCBHCFC_00892 4.94e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
MDCBHCFC_00893 2.14e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDCBHCFC_00894 5.68e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MDCBHCFC_00895 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MDCBHCFC_00896 2.23e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MDCBHCFC_00897 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MDCBHCFC_00898 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MDCBHCFC_00899 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
MDCBHCFC_00900 2.27e-103 ypmB - - S - - - protein conserved in bacteria
MDCBHCFC_00901 6.2e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MDCBHCFC_00902 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
MDCBHCFC_00903 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
MDCBHCFC_00904 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDCBHCFC_00905 2.37e-120 ypoC - - - - - - -
MDCBHCFC_00906 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MDCBHCFC_00907 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDCBHCFC_00908 1.99e-235 yppC - - S - - - Protein of unknown function (DUF2515)
MDCBHCFC_00911 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
MDCBHCFC_00912 9.21e-11 - - - S - - - YppF-like protein
MDCBHCFC_00913 1.45e-66 yppG - - S - - - YppG-like protein
MDCBHCFC_00914 2.06e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MDCBHCFC_00915 5.3e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
MDCBHCFC_00916 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MDCBHCFC_00917 1.39e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
MDCBHCFC_00918 5.9e-129 ypsA - - S - - - Belongs to the UPF0398 family
MDCBHCFC_00919 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDCBHCFC_00920 1.01e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MDCBHCFC_00921 9.72e-66 yqgA - - - - - - -
MDCBHCFC_00923 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
MDCBHCFC_00924 4.63e-176 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_00925 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MDCBHCFC_00926 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
MDCBHCFC_00927 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
MDCBHCFC_00928 1.03e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
MDCBHCFC_00929 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MDCBHCFC_00930 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MDCBHCFC_00931 9.13e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDCBHCFC_00932 4.98e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
MDCBHCFC_00933 2.63e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
MDCBHCFC_00934 1.36e-112 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
MDCBHCFC_00935 0.0 ypbR - - S - - - Dynamin family
MDCBHCFC_00936 6.77e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
MDCBHCFC_00937 1.08e-11 - - - - - - - -
MDCBHCFC_00938 2.26e-213 ypcP - - L - - - 5'3' exonuclease
MDCBHCFC_00939 5.23e-05 - - - - ko:K06429 - ko00000 -
MDCBHCFC_00940 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
MDCBHCFC_00941 9.36e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MDCBHCFC_00942 1.1e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
MDCBHCFC_00943 1.54e-37 ypeQ - - S - - - Zinc-finger
MDCBHCFC_00944 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
MDCBHCFC_00945 1.17e-22 degR - - - - - - -
MDCBHCFC_00946 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MDCBHCFC_00947 2.12e-275 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MDCBHCFC_00948 1.23e-224 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MDCBHCFC_00949 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MDCBHCFC_00950 2.42e-140 yagB - - S ko:K06950 - ko00000 phosphohydrolase
MDCBHCFC_00951 5.44e-202 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
MDCBHCFC_00952 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
MDCBHCFC_00953 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
MDCBHCFC_00954 2.81e-183 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
MDCBHCFC_00955 3.47e-148 ypjP - - S - - - YpjP-like protein
MDCBHCFC_00956 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MDCBHCFC_00957 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDCBHCFC_00958 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MDCBHCFC_00959 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
MDCBHCFC_00960 1.4e-236 yplP - - K - - - Transcriptional regulator
MDCBHCFC_00961 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MDCBHCFC_00962 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
MDCBHCFC_00963 7.93e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MDCBHCFC_00964 1.82e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
MDCBHCFC_00965 1.95e-128 ypmS - - S - - - protein conserved in bacteria
MDCBHCFC_00966 8.69e-40 ypmT - - S - - - Uncharacterized ympT
MDCBHCFC_00967 9.99e-290 mepA - - V - - - MATE efflux family protein
MDCBHCFC_00968 4.14e-94 ypoP - - K - - - transcriptional
MDCBHCFC_00969 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDCBHCFC_00970 2.04e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MDCBHCFC_00971 3.35e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MDCBHCFC_00972 9.41e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
MDCBHCFC_00973 1.89e-227 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
MDCBHCFC_00974 1.79e-82 cgeA - - - ko:K06319 - ko00000 -
MDCBHCFC_00975 1.06e-59 cgeC - - - ko:K06321 - ko00000 -
MDCBHCFC_00976 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
MDCBHCFC_00977 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
MDCBHCFC_00979 3.74e-316 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDCBHCFC_00980 1.97e-160 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MDCBHCFC_00981 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MDCBHCFC_00982 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
MDCBHCFC_00983 5.27e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
MDCBHCFC_00984 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
MDCBHCFC_00985 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
MDCBHCFC_00986 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
MDCBHCFC_00987 7.44e-159 yodN - - - - - - -
MDCBHCFC_00989 5.18e-34 yozD - - S - - - YozD-like protein
MDCBHCFC_00990 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MDCBHCFC_00991 1.17e-71 yodL - - S - - - YodL-like
MDCBHCFC_00992 2.08e-12 - - - - - - - -
MDCBHCFC_00993 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MDCBHCFC_00994 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MDCBHCFC_00995 4.86e-41 yodI - - - - - - -
MDCBHCFC_00996 3.03e-166 yodH - - Q - - - Methyltransferase
MDCBHCFC_00997 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MDCBHCFC_00998 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDCBHCFC_00999 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
MDCBHCFC_01000 1.38e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MDCBHCFC_01001 2.64e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
MDCBHCFC_01002 1.11e-139 yodC - - C - - - nitroreductase
MDCBHCFC_01003 2.63e-73 yodB - - K - - - transcriptional
MDCBHCFC_01004 3.97e-84 iolK - - S - - - tautomerase
MDCBHCFC_01005 1.78e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MDCBHCFC_01006 5.59e-14 - - - - - - - -
MDCBHCFC_01007 2.88e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
MDCBHCFC_01008 2.33e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
MDCBHCFC_01009 1.85e-58 - - - - - - - -
MDCBHCFC_01010 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
MDCBHCFC_01011 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
MDCBHCFC_01012 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDCBHCFC_01013 2.06e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
MDCBHCFC_01015 3.54e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDCBHCFC_01016 1.32e-292 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
MDCBHCFC_01017 5.28e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MDCBHCFC_01018 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MDCBHCFC_01019 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
MDCBHCFC_01020 0.0 yojO - - P - - - Von Willebrand factor
MDCBHCFC_01021 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MDCBHCFC_01022 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MDCBHCFC_01023 1.11e-212 yocS - - S ko:K03453 - ko00000 -transporter
MDCBHCFC_01024 2.52e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MDCBHCFC_01025 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
MDCBHCFC_01026 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
MDCBHCFC_01027 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MDCBHCFC_01028 1.91e-42 yozC - - - - - - -
MDCBHCFC_01029 2.17e-74 yozO - - S - - - Bacterial PH domain
MDCBHCFC_01030 1.83e-49 yocN - - - - - - -
MDCBHCFC_01031 2.94e-55 yozN - - - - - - -
MDCBHCFC_01032 5.43e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MDCBHCFC_01033 3.93e-41 - - - - - - - -
MDCBHCFC_01034 4.29e-70 yocL - - - - - - -
MDCBHCFC_01035 1.42e-107 yocK - - T - - - general stress protein
MDCBHCFC_01036 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDCBHCFC_01037 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
MDCBHCFC_01038 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
MDCBHCFC_01039 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDCBHCFC_01040 1.22e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_01041 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
MDCBHCFC_01042 2.25e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
MDCBHCFC_01043 1.08e-121 yocC - - - - - - -
MDCBHCFC_01044 2.6e-185 - - - - - - - -
MDCBHCFC_01045 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
MDCBHCFC_01046 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MDCBHCFC_01047 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
MDCBHCFC_01048 2.58e-121 yobW - - - - - - -
MDCBHCFC_01049 2.37e-221 yobV - - K - - - WYL domain
MDCBHCFC_01050 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
MDCBHCFC_01051 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MDCBHCFC_01052 3.09e-127 yobS - - K - - - Transcriptional regulator
MDCBHCFC_01053 3.42e-179 - - - J - - - FR47-like protein
MDCBHCFC_01054 4.48e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
MDCBHCFC_01055 1.75e-69 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
MDCBHCFC_01056 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
MDCBHCFC_01057 1.62e-131 yokH - - G - - - SMI1 / KNR4 family
MDCBHCFC_01058 2.81e-21 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MDCBHCFC_01059 1.91e-34 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDCBHCFC_01060 2.77e-26 - - - - - - - -
MDCBHCFC_01062 7.88e-135 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MDCBHCFC_01064 9.95e-23 - - - - - - - -
MDCBHCFC_01065 5.37e-85 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
MDCBHCFC_01067 3.62e-151 - - - - - - - -
MDCBHCFC_01068 1.74e-14 - - - - - - - -
MDCBHCFC_01069 2.11e-49 - - - S - - - TM2 domain
MDCBHCFC_01070 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
MDCBHCFC_01071 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
MDCBHCFC_01074 2.54e-215 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
MDCBHCFC_01075 3.73e-151 lin0465 - - S - - - DJ-1/PfpI family
MDCBHCFC_01076 6.84e-103 yoaW - - - - - - -
MDCBHCFC_01077 1.11e-202 yoaV - - EG - - - EamA-like transporter family
MDCBHCFC_01078 1.91e-202 yoaU - - K - - - LysR substrate binding domain
MDCBHCFC_01079 9.44e-190 yoaT - - S - - - Protein of unknown function (DUF817)
MDCBHCFC_01080 7e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_01081 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
MDCBHCFC_01082 8.56e-217 yoaR - - V - - - vancomycin resistance protein
MDCBHCFC_01083 1.53e-112 - - - - - - - -
MDCBHCFC_01084 3.64e-23 yoaP - - K - - - YoaP-like
MDCBHCFC_01086 3.62e-292 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MDCBHCFC_01089 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
MDCBHCFC_01090 5e-253 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
MDCBHCFC_01091 1.79e-145 yoaK - - S - - - Membrane
MDCBHCFC_01092 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
MDCBHCFC_01093 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
MDCBHCFC_01094 3.89e-283 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
MDCBHCFC_01095 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
MDCBHCFC_01096 1.25e-20 - - - - - - - -
MDCBHCFC_01097 1.17e-12 - - - - - - - -
MDCBHCFC_01098 1.99e-114 degA - - K - - - Transcriptional regulator
MDCBHCFC_01099 3.73e-193 - 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
MDCBHCFC_01100 3.41e-259 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
MDCBHCFC_01101 4.76e-215 - - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDCBHCFC_01102 4.94e-43 yoaF - - - - - - -
MDCBHCFC_01103 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDCBHCFC_01104 1.37e-233 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDCBHCFC_01105 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
MDCBHCFC_01106 6.14e-298 yoaB - - EGP - - - the major facilitator superfamily
MDCBHCFC_01107 1.9e-121 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDCBHCFC_01108 4.08e-171 yoxB - - - - - - -
MDCBHCFC_01109 6.37e-50 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
MDCBHCFC_01110 2.28e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_01111 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MDCBHCFC_01112 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDCBHCFC_01113 1.29e-259 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDCBHCFC_01114 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_01115 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
MDCBHCFC_01116 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MDCBHCFC_01117 4.88e-236 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MDCBHCFC_01118 1.69e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_01119 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MDCBHCFC_01120 1.92e-46 yoeD - - G - - - Helix-turn-helix domain
MDCBHCFC_01121 1.14e-124 - - - L - - - Integrase
MDCBHCFC_01123 5.87e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
MDCBHCFC_01124 9.8e-313 yoeA - - V - - - MATE efflux family protein
MDCBHCFC_01125 1.35e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MDCBHCFC_01126 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MDCBHCFC_01127 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCBHCFC_01128 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCBHCFC_01129 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCBHCFC_01130 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCBHCFC_01131 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
MDCBHCFC_01132 7.1e-83 yngL - - S - - - Protein of unknown function (DUF1360)
MDCBHCFC_01133 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
MDCBHCFC_01134 3.94e-33 - - - S - - - Family of unknown function (DUF5367)
MDCBHCFC_01135 7.59e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MDCBHCFC_01136 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MDCBHCFC_01137 9.36e-317 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
MDCBHCFC_01138 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
MDCBHCFC_01139 1.65e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
MDCBHCFC_01140 6.03e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
MDCBHCFC_01141 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MDCBHCFC_01142 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
MDCBHCFC_01143 2.01e-134 yngC - - S - - - membrane-associated protein
MDCBHCFC_01144 1.12e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MDCBHCFC_01145 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MDCBHCFC_01146 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
MDCBHCFC_01148 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
MDCBHCFC_01149 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MDCBHCFC_01150 8.74e-75 ynfC - - - - - - -
MDCBHCFC_01151 1.82e-18 - - - - - - - -
MDCBHCFC_01152 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDCBHCFC_01153 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDCBHCFC_01154 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
MDCBHCFC_01155 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDCBHCFC_01156 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
MDCBHCFC_01157 4.68e-71 yneQ - - - - - - -
MDCBHCFC_01158 4.02e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MDCBHCFC_01159 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
MDCBHCFC_01161 9.26e-10 - - - S - - - Fur-regulated basic protein B
MDCBHCFC_01162 7.25e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MDCBHCFC_01163 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MDCBHCFC_01164 3.27e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
MDCBHCFC_01165 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
MDCBHCFC_01166 2.35e-84 cotM - - O ko:K06335 - ko00000 Spore coat protein
MDCBHCFC_01167 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
MDCBHCFC_01168 3.57e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
MDCBHCFC_01169 2.12e-77 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
MDCBHCFC_01170 1.68e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
MDCBHCFC_01171 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
MDCBHCFC_01172 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MDCBHCFC_01173 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
MDCBHCFC_01174 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MDCBHCFC_01175 1.15e-43 ynzC - - S - - - UPF0291 protein
MDCBHCFC_01176 3.97e-145 yneB - - L - - - resolvase
MDCBHCFC_01177 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MDCBHCFC_01178 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDCBHCFC_01179 1.22e-101 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MDCBHCFC_01180 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
MDCBHCFC_01181 1.27e-172 yndL - - S - - - Replication protein
MDCBHCFC_01183 0.0 yndJ - - S - - - YndJ-like protein
MDCBHCFC_01184 6.98e-149 - - - S - - - Domain of unknown function (DUF4166)
MDCBHCFC_01185 2.07e-195 yndG - - S - - - DoxX-like family
MDCBHCFC_01186 7.59e-287 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
MDCBHCFC_01187 1.26e-246 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
MDCBHCFC_01188 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MDCBHCFC_01191 1.05e-102 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
MDCBHCFC_01192 1.04e-94 - - - - - - - -
MDCBHCFC_01193 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
MDCBHCFC_01196 2.3e-162 - - - S - - - Domain of unknown function, YrpD
MDCBHCFC_01198 2.75e-210 - - - S - - - Thymidylate synthase
MDCBHCFC_01201 3.51e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
MDCBHCFC_01202 6.41e-106 - - - S - - - Protein of unknown function (DUF2691)
MDCBHCFC_01203 1.45e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDCBHCFC_01204 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDCBHCFC_01205 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
MDCBHCFC_01206 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
MDCBHCFC_01207 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
MDCBHCFC_01208 1.05e-276 xylR - - GK - - - ROK family
MDCBHCFC_01209 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
MDCBHCFC_01210 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
MDCBHCFC_01211 1.24e-109 - - - E - - - phosphoribosylanthranilate isomerase activity
MDCBHCFC_01213 3.84e-75 ynaF - - - - - - -
MDCBHCFC_01214 8.1e-100 - - - S - - - Domain of unknown function (DUF3885)
MDCBHCFC_01215 6.12e-47 - - - S - - - Domain of unknown function (DUF3885)
MDCBHCFC_01216 6.99e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
MDCBHCFC_01217 1.3e-05 ynaC - - - - - - -
MDCBHCFC_01218 1.32e-103 - - - G - - - SMI1-KNR4 cell-wall
MDCBHCFC_01219 4.15e-49 - - - - - - - -
MDCBHCFC_01220 9.9e-155 - - - - - - - -
MDCBHCFC_01222 8.68e-14 - - - - - - - -
MDCBHCFC_01224 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MDCBHCFC_01225 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
MDCBHCFC_01226 2.77e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MDCBHCFC_01227 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDCBHCFC_01228 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
MDCBHCFC_01229 2.23e-147 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MDCBHCFC_01230 2.24e-141 - - - - - - - -
MDCBHCFC_01231 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDCBHCFC_01232 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDCBHCFC_01233 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
MDCBHCFC_01234 1.2e-30 ymzA - - - - - - -
MDCBHCFC_01235 1.63e-31 - - - - - - - -
MDCBHCFC_01236 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MDCBHCFC_01237 1.38e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDCBHCFC_01238 5.41e-76 ymaF - - S - - - YmaF family
MDCBHCFC_01240 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MDCBHCFC_01241 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
MDCBHCFC_01242 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
MDCBHCFC_01243 3.96e-163 ymaC - - S - - - Replication protein
MDCBHCFC_01245 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
MDCBHCFC_01246 8.93e-206 - - - S - - - Metallo-beta-lactamase superfamily
MDCBHCFC_01247 8.03e-81 ymzB - - - - - - -
MDCBHCFC_01248 2.29e-293 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MDCBHCFC_01249 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
MDCBHCFC_01250 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MDCBHCFC_01251 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MDCBHCFC_01252 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
MDCBHCFC_01253 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
MDCBHCFC_01254 4.47e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
MDCBHCFC_01255 2.78e-181 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
MDCBHCFC_01256 1.61e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
MDCBHCFC_01257 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDCBHCFC_01258 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
MDCBHCFC_01259 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MDCBHCFC_01260 2.14e-232 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
MDCBHCFC_01262 1.25e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MDCBHCFC_01263 9.47e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
MDCBHCFC_01264 2.32e-138 pksA - - K - - - Transcriptional regulator
MDCBHCFC_01265 4.61e-126 ymcC - - S - - - Membrane
MDCBHCFC_01267 1.91e-91 - - - S - - - Regulatory protein YrvL
MDCBHCFC_01268 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDCBHCFC_01269 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDCBHCFC_01270 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
MDCBHCFC_01271 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
MDCBHCFC_01272 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MDCBHCFC_01273 1.69e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MDCBHCFC_01274 1.96e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MDCBHCFC_01275 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
MDCBHCFC_01276 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
MDCBHCFC_01277 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MDCBHCFC_01278 6.36e-277 pbpX - - V - - - Beta-lactamase
MDCBHCFC_01279 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDCBHCFC_01280 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MDCBHCFC_01281 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDCBHCFC_01282 8.75e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
MDCBHCFC_01283 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
MDCBHCFC_01284 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
MDCBHCFC_01285 1.01e-164 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MDCBHCFC_01286 4.79e-309 ymfH - - S - - - zinc protease
MDCBHCFC_01287 9.47e-299 albE - - S - - - Peptidase M16
MDCBHCFC_01288 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_01289 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_01290 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MDCBHCFC_01291 4.94e-44 - - - S - - - YlzJ-like protein
MDCBHCFC_01292 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
MDCBHCFC_01293 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDCBHCFC_01294 1.83e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDCBHCFC_01295 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MDCBHCFC_01296 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDCBHCFC_01297 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MDCBHCFC_01298 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
MDCBHCFC_01299 1.53e-56 ymxH - - S - - - YlmC YmxH family
MDCBHCFC_01300 9.36e-295 mlpA - - S - - - Belongs to the peptidase M16 family
MDCBHCFC_01301 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
MDCBHCFC_01302 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MDCBHCFC_01303 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDCBHCFC_01304 2.7e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MDCBHCFC_01305 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDCBHCFC_01306 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDCBHCFC_01307 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
MDCBHCFC_01308 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDCBHCFC_01309 6.16e-63 ylxQ - - J - - - ribosomal protein
MDCBHCFC_01310 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
MDCBHCFC_01311 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MDCBHCFC_01312 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MDCBHCFC_01313 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDCBHCFC_01314 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDCBHCFC_01315 2.78e-293 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MDCBHCFC_01316 5.64e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MDCBHCFC_01317 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MDCBHCFC_01318 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDCBHCFC_01319 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDCBHCFC_01320 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MDCBHCFC_01321 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDCBHCFC_01322 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MDCBHCFC_01323 4e-100 ylxL - - - - - - -
MDCBHCFC_01324 1.33e-175 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDCBHCFC_01325 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MDCBHCFC_01326 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MDCBHCFC_01327 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
MDCBHCFC_01328 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
MDCBHCFC_01329 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MDCBHCFC_01330 3.14e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
MDCBHCFC_01331 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
MDCBHCFC_01332 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MDCBHCFC_01333 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MDCBHCFC_01334 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
MDCBHCFC_01335 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
MDCBHCFC_01336 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
MDCBHCFC_01337 1.3e-135 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
MDCBHCFC_01338 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
MDCBHCFC_01339 4.7e-245 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MDCBHCFC_01340 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MDCBHCFC_01341 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
MDCBHCFC_01342 1.66e-174 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
MDCBHCFC_01343 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
MDCBHCFC_01344 5.52e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
MDCBHCFC_01345 1.51e-78 ylxF - - S - - - MgtE intracellular N domain
MDCBHCFC_01346 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
MDCBHCFC_01347 1e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MDCBHCFC_01348 1.57e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
MDCBHCFC_01349 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MDCBHCFC_01350 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
MDCBHCFC_01351 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
MDCBHCFC_01352 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
MDCBHCFC_01353 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MDCBHCFC_01354 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MDCBHCFC_01355 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDCBHCFC_01356 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDCBHCFC_01357 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
MDCBHCFC_01358 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDCBHCFC_01359 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDCBHCFC_01360 1.42e-212 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
MDCBHCFC_01361 3.09e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MDCBHCFC_01362 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MDCBHCFC_01363 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
MDCBHCFC_01364 0.0 ylqG - - - - - - -
MDCBHCFC_01365 1.37e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDCBHCFC_01366 1.15e-199 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDCBHCFC_01367 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDCBHCFC_01368 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MDCBHCFC_01369 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDCBHCFC_01370 3.41e-80 ylqD - - S - - - YlqD protein
MDCBHCFC_01371 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MDCBHCFC_01372 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MDCBHCFC_01373 1.32e-306 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDCBHCFC_01374 8.01e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDCBHCFC_01375 1.67e-114 - - - - - - - -
MDCBHCFC_01376 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDCBHCFC_01377 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MDCBHCFC_01378 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDCBHCFC_01379 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDCBHCFC_01380 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MDCBHCFC_01381 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
MDCBHCFC_01382 1.68e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDCBHCFC_01383 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MDCBHCFC_01384 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDCBHCFC_01385 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MDCBHCFC_01386 5.89e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
MDCBHCFC_01387 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
MDCBHCFC_01388 3.65e-78 yloU - - S - - - protein conserved in bacteria
MDCBHCFC_01389 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MDCBHCFC_01390 4.7e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MDCBHCFC_01391 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MDCBHCFC_01392 1.12e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDCBHCFC_01393 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MDCBHCFC_01394 2.05e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MDCBHCFC_01395 3.07e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MDCBHCFC_01396 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDCBHCFC_01397 1.49e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDCBHCFC_01398 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDCBHCFC_01399 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDCBHCFC_01400 4.21e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDCBHCFC_01401 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDCBHCFC_01402 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MDCBHCFC_01403 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
MDCBHCFC_01404 8.41e-202 yloC - - S - - - stress-induced protein
MDCBHCFC_01405 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
MDCBHCFC_01406 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
MDCBHCFC_01407 4.6e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
MDCBHCFC_01408 2.06e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
MDCBHCFC_01409 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MDCBHCFC_01410 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MDCBHCFC_01411 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MDCBHCFC_01412 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
MDCBHCFC_01413 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MDCBHCFC_01415 2.57e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDCBHCFC_01416 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDCBHCFC_01417 1.49e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDCBHCFC_01418 2.05e-180 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MDCBHCFC_01419 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
MDCBHCFC_01420 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MDCBHCFC_01421 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDCBHCFC_01422 4.21e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MDCBHCFC_01423 1.97e-291 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
MDCBHCFC_01424 1.81e-121 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDCBHCFC_01425 2.04e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MDCBHCFC_01426 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDCBHCFC_01427 3.74e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
MDCBHCFC_01428 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDCBHCFC_01429 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
MDCBHCFC_01430 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
MDCBHCFC_01431 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
MDCBHCFC_01432 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDCBHCFC_01433 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MDCBHCFC_01434 3.73e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
MDCBHCFC_01435 3.58e-51 ylmC - - S - - - sporulation protein
MDCBHCFC_01436 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
MDCBHCFC_01437 1.1e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MDCBHCFC_01438 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDCBHCFC_01439 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDCBHCFC_01440 1.23e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MDCBHCFC_01442 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
MDCBHCFC_01443 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDCBHCFC_01444 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDCBHCFC_01445 5.37e-76 sbp - - S - - - small basic protein
MDCBHCFC_01446 8.67e-132 ylxX - - S - - - protein conserved in bacteria
MDCBHCFC_01447 1.35e-143 ylxW - - S - - - protein conserved in bacteria
MDCBHCFC_01448 3.37e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDCBHCFC_01449 3.74e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
MDCBHCFC_01450 4.48e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDCBHCFC_01451 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MDCBHCFC_01452 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDCBHCFC_01453 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDCBHCFC_01454 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDCBHCFC_01455 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
MDCBHCFC_01456 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MDCBHCFC_01457 3.42e-68 ftsL - - D - - - Essential cell division protein
MDCBHCFC_01458 4.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDCBHCFC_01459 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MDCBHCFC_01460 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MDCBHCFC_01461 1.66e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDCBHCFC_01462 1.33e-115 ylbP - - K - - - n-acetyltransferase
MDCBHCFC_01463 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MDCBHCFC_01464 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MDCBHCFC_01465 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
MDCBHCFC_01467 8.29e-292 ylbM - - S - - - Belongs to the UPF0348 family
MDCBHCFC_01468 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MDCBHCFC_01469 3.64e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
MDCBHCFC_01470 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
MDCBHCFC_01471 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDCBHCFC_01472 6.07e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
MDCBHCFC_01473 4.36e-52 ylbG - - S - - - UPF0298 protein
MDCBHCFC_01474 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
MDCBHCFC_01475 1.73e-48 ylbE - - S - - - YlbE-like protein
MDCBHCFC_01476 1.32e-88 ylbD - - S - - - Putative coat protein
MDCBHCFC_01477 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
MDCBHCFC_01478 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
MDCBHCFC_01479 1.61e-81 ylbA - - S - - - YugN-like family
MDCBHCFC_01480 1.21e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
MDCBHCFC_01481 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MDCBHCFC_01482 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MDCBHCFC_01483 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDCBHCFC_01484 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MDCBHCFC_01485 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MDCBHCFC_01486 2.85e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MDCBHCFC_01487 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MDCBHCFC_01488 7.05e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MDCBHCFC_01489 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
MDCBHCFC_01490 2.87e-218 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MDCBHCFC_01491 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MDCBHCFC_01492 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
MDCBHCFC_01493 1.64e-124 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDCBHCFC_01494 8.92e-44 ylaI - - S - - - protein conserved in bacteria
MDCBHCFC_01495 8.88e-63 ylaH - - S - - - YlaH-like protein
MDCBHCFC_01496 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MDCBHCFC_01497 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
MDCBHCFC_01498 5.7e-56 ylaE - - - - - - -
MDCBHCFC_01500 1.19e-86 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_01501 1.44e-56 ylaB - - - - - - -
MDCBHCFC_01502 0.0 ylaA - - - - - - -
MDCBHCFC_01503 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MDCBHCFC_01504 2.47e-221 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MDCBHCFC_01505 1.36e-96 ykzC - - S - - - Acetyltransferase (GNAT) family
MDCBHCFC_01506 1.51e-191 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
MDCBHCFC_01507 4.48e-35 ykzI - - - - - - -
MDCBHCFC_01508 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
MDCBHCFC_01509 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
MDCBHCFC_01510 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
MDCBHCFC_01511 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MDCBHCFC_01512 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDCBHCFC_01513 8.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDCBHCFC_01514 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDCBHCFC_01515 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDCBHCFC_01516 1.06e-138 ykyA - - L - - - Putative cell-wall binding lipoprotein
MDCBHCFC_01517 1.26e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MDCBHCFC_01518 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDCBHCFC_01519 6.8e-186 ykrA - - S - - - hydrolases of the HAD superfamily
MDCBHCFC_01520 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
MDCBHCFC_01521 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDCBHCFC_01522 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MDCBHCFC_01523 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MDCBHCFC_01524 9.81e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
MDCBHCFC_01525 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MDCBHCFC_01526 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
MDCBHCFC_01527 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
MDCBHCFC_01528 1.09e-18 - - - S - - - Uncharacterized protein YkpC
MDCBHCFC_01529 2.42e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
MDCBHCFC_01530 2.75e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDCBHCFC_01531 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDCBHCFC_01532 5.43e-52 ykoA - - - - - - -
MDCBHCFC_01533 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MDCBHCFC_01534 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MDCBHCFC_01535 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
MDCBHCFC_01536 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_01537 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MDCBHCFC_01538 3.53e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_01539 1.16e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MDCBHCFC_01540 5.97e-147 yknW - - S - - - Yip1 domain
MDCBHCFC_01541 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MDCBHCFC_01542 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MDCBHCFC_01543 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MDCBHCFC_01544 4.47e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
MDCBHCFC_01545 5.71e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
MDCBHCFC_01546 3.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
MDCBHCFC_01547 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MDCBHCFC_01548 3.08e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MDCBHCFC_01549 2.83e-199 yknT - - - ko:K06437 - ko00000 -
MDCBHCFC_01550 1.78e-120 rok - - K - - - Repressor of ComK
MDCBHCFC_01551 2.45e-103 ykuV - - CO - - - thiol-disulfide
MDCBHCFC_01552 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
MDCBHCFC_01553 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
MDCBHCFC_01554 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
MDCBHCFC_01555 1.27e-272 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDCBHCFC_01556 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDCBHCFC_01557 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
MDCBHCFC_01558 2.12e-223 ykuO - - - - - - -
MDCBHCFC_01559 1.23e-110 - - - C ko:K03839 - ko00000 Flavodoxin domain
MDCBHCFC_01560 6.52e-216 ccpC - - K - - - Transcriptional regulator
MDCBHCFC_01561 5.15e-100 ykuL - - S - - - CBS domain
MDCBHCFC_01562 7.83e-38 ykzF - - S - - - Antirepressor AbbA
MDCBHCFC_01563 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
MDCBHCFC_01564 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
MDCBHCFC_01565 3.55e-298 ykuI - - T - - - Diguanylate phosphodiesterase
MDCBHCFC_01566 2.13e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_01567 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
MDCBHCFC_01568 5.84e-115 ykuD - - S - - - protein conserved in bacteria
MDCBHCFC_01569 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_01570 3.71e-110 ykyB - - S - - - YkyB-like protein
MDCBHCFC_01571 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
MDCBHCFC_01572 1.05e-22 - - - - - - - -
MDCBHCFC_01573 1.46e-283 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MDCBHCFC_01574 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_01575 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MDCBHCFC_01576 5.14e-170 ykwD - - J - - - protein with SCP PR1 domains
MDCBHCFC_01577 1.68e-17 vgb - - H ko:K18235 - ko00000,ko01000,ko01504 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
MDCBHCFC_01578 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MDCBHCFC_01579 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MDCBHCFC_01580 3.08e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDCBHCFC_01581 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
MDCBHCFC_01582 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_01583 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDCBHCFC_01584 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
MDCBHCFC_01585 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_01586 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
MDCBHCFC_01588 5.43e-229 ykvZ - - K - - - Transcriptional regulator
MDCBHCFC_01590 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
MDCBHCFC_01591 3.99e-09 - - - - - - - -
MDCBHCFC_01592 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MDCBHCFC_01593 2.76e-115 stoA - - CO - - - thiol-disulfide
MDCBHCFC_01594 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDCBHCFC_01595 5.26e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
MDCBHCFC_01596 2.6e-39 - - - - - - - -
MDCBHCFC_01597 5.43e-35 ykvS - - S - - - protein conserved in bacteria
MDCBHCFC_01598 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
MDCBHCFC_01599 1.01e-203 - - - G - - - Glycosyl hydrolases family 18
MDCBHCFC_01600 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
MDCBHCFC_01601 5.83e-293 - - - M - - - Glycosyl transferases group 1
MDCBHCFC_01602 3.81e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MDCBHCFC_01603 9.79e-80 ykvN - - K - - - Transcriptional regulator
MDCBHCFC_01604 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MDCBHCFC_01605 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MDCBHCFC_01606 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
MDCBHCFC_01607 6.42e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MDCBHCFC_01608 1.66e-227 ykvI - - S - - - membrane
MDCBHCFC_01609 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MDCBHCFC_01610 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
MDCBHCFC_01611 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
MDCBHCFC_01612 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
MDCBHCFC_01613 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
MDCBHCFC_01614 5.84e-95 eag - - - - - - -
MDCBHCFC_01616 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
MDCBHCFC_01617 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MDCBHCFC_01618 4.34e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MDCBHCFC_01619 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MDCBHCFC_01620 1.61e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MDCBHCFC_01621 1.88e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MDCBHCFC_01622 9.48e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MDCBHCFC_01623 2.37e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MDCBHCFC_01624 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MDCBHCFC_01626 4.58e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDCBHCFC_01627 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_01628 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
MDCBHCFC_01629 1.77e-28 ykzE - - - - - - -
MDCBHCFC_01631 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
MDCBHCFC_01632 2.29e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MDCBHCFC_01633 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
MDCBHCFC_01634 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
MDCBHCFC_01635 7.73e-197 rsgI - - S - - - Anti-sigma factor N-terminus
MDCBHCFC_01636 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDCBHCFC_01637 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MDCBHCFC_01638 5.71e-142 ykoX - - S - - - membrane-associated protein
MDCBHCFC_01639 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
MDCBHCFC_01640 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MDCBHCFC_01641 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
MDCBHCFC_01642 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
MDCBHCFC_01643 0.0 ykoS - - - - - - -
MDCBHCFC_01644 2.07e-196 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MDCBHCFC_01645 2.38e-127 ykoP - - G - - - polysaccharide deacetylase
MDCBHCFC_01646 4.65e-279 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MDCBHCFC_01647 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
MDCBHCFC_01648 3.04e-36 ykoL - - - - - - -
MDCBHCFC_01649 1.63e-25 - - - - - - - -
MDCBHCFC_01650 1.49e-70 tnrA - - K - - - transcriptional
MDCBHCFC_01651 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MDCBHCFC_01653 1.45e-08 - - - - - - - -
MDCBHCFC_01654 1.51e-110 ykoJ - - S - - - Peptidase propeptide and YPEB domain
MDCBHCFC_01655 1.36e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
MDCBHCFC_01656 3.27e-311 ykoH - - T - - - Histidine kinase
MDCBHCFC_01657 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_01658 1.72e-142 ykoF - - S - - - YKOF-related Family
MDCBHCFC_01659 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MDCBHCFC_01660 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_01661 2.57e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MDCBHCFC_01662 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDCBHCFC_01663 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MDCBHCFC_01664 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MDCBHCFC_01665 1.9e-113 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
MDCBHCFC_01666 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
MDCBHCFC_01667 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
MDCBHCFC_01668 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
MDCBHCFC_01669 1.08e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MDCBHCFC_01670 4.3e-255 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDCBHCFC_01671 1.94e-216 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MDCBHCFC_01672 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
MDCBHCFC_01673 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
MDCBHCFC_01674 1.2e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDCBHCFC_01675 6.42e-128 ykkA - - S - - - Protein of unknown function (DUF664)
MDCBHCFC_01676 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
MDCBHCFC_01677 2.11e-16 - - - - - - - -
MDCBHCFC_01678 1.26e-287 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MDCBHCFC_01679 8.79e-120 ykhA - - I - - - Acyl-CoA hydrolase
MDCBHCFC_01680 5.1e-205 ykgA - - E - - - Amidinotransferase
MDCBHCFC_01681 2.59e-257 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
MDCBHCFC_01682 3.43e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDCBHCFC_01683 7.9e-214 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MDCBHCFC_01684 5.42e-254 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MDCBHCFC_01685 7.57e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
MDCBHCFC_01687 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDCBHCFC_01688 2.23e-235 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDCBHCFC_01689 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDCBHCFC_01690 7.96e-203 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDCBHCFC_01691 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
MDCBHCFC_01692 9.56e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
MDCBHCFC_01693 8.96e-280 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDCBHCFC_01694 4.47e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MDCBHCFC_01695 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDCBHCFC_01696 2.31e-232 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MDCBHCFC_01697 8.6e-308 steT - - E ko:K03294 - ko00000 amino acid
MDCBHCFC_01698 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
MDCBHCFC_01699 4.42e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
MDCBHCFC_01700 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
MDCBHCFC_01701 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
MDCBHCFC_01702 2.16e-207 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
MDCBHCFC_01703 1.15e-52 xhlB - - S - - - SPP1 phage holin
MDCBHCFC_01704 7.71e-52 xhlA - - S - - - Haemolysin XhlA
MDCBHCFC_01705 4.34e-198 xepA - - - - - - -
MDCBHCFC_01706 1.82e-30 xkdX - - - - - - -
MDCBHCFC_01707 2.78e-54 xkdW - - S - - - XkdW protein
MDCBHCFC_01708 0.0 - - - - - - - -
MDCBHCFC_01709 4.43e-56 - - - - - - - -
MDCBHCFC_01710 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
MDCBHCFC_01711 8.85e-244 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MDCBHCFC_01712 5.43e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
MDCBHCFC_01713 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
MDCBHCFC_01714 1.34e-231 xkdQ - - G - - - NLP P60 protein
MDCBHCFC_01715 7.2e-158 xkdP - - S - - - Lysin motif
MDCBHCFC_01716 0.0 xkdO - - L - - - Transglycosylase SLT domain
MDCBHCFC_01717 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
MDCBHCFC_01718 6.01e-99 xkdM - - S - - - Phage tail tube protein
MDCBHCFC_01719 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
MDCBHCFC_01720 2.87e-101 xkdJ - - - - - - -
MDCBHCFC_01721 2.38e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
MDCBHCFC_01722 8.67e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
MDCBHCFC_01723 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
MDCBHCFC_01724 3.91e-217 xkdG - - S - - - Phage capsid family
MDCBHCFC_01725 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
MDCBHCFC_01726 0.0 yqbA - - S - - - portal protein
MDCBHCFC_01727 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
MDCBHCFC_01728 1.6e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
MDCBHCFC_01729 1.35e-108 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MDCBHCFC_01733 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
MDCBHCFC_01734 1.07e-202 xkdB - - K - - - sequence-specific DNA binding
MDCBHCFC_01736 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
MDCBHCFC_01737 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
MDCBHCFC_01738 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
MDCBHCFC_01739 1.11e-138 yjqB - - S - - - Pfam:DUF867
MDCBHCFC_01740 2.24e-79 yjqA - - S - - - Bacterial PH domain
MDCBHCFC_01741 1.26e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MDCBHCFC_01742 1.79e-55 - - - S - - - YCII-related domain
MDCBHCFC_01744 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MDCBHCFC_01745 7.1e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
MDCBHCFC_01746 2.71e-103 yjoA - - S - - - DinB family
MDCBHCFC_01747 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
MDCBHCFC_01748 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MDCBHCFC_01749 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
MDCBHCFC_01750 8.11e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
MDCBHCFC_01751 4.58e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
MDCBHCFC_01752 1.29e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_01753 2.18e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
MDCBHCFC_01754 2.65e-245 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
MDCBHCFC_01755 6.97e-240 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
MDCBHCFC_01756 2.92e-312 - - - G ko:K03292 - ko00000 symporter YjmB
MDCBHCFC_01757 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MDCBHCFC_01758 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MDCBHCFC_01759 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
MDCBHCFC_01760 2.36e-116 yjlB - - S - - - Cupin domain
MDCBHCFC_01761 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
MDCBHCFC_01762 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDCBHCFC_01763 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
MDCBHCFC_01764 7.14e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
MDCBHCFC_01765 1.11e-41 - - - - - - - -
MDCBHCFC_01766 7.18e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MDCBHCFC_01767 1.93e-285 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MDCBHCFC_01769 4.85e-143 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MDCBHCFC_01771 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
MDCBHCFC_01772 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
MDCBHCFC_01773 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
MDCBHCFC_01774 3.78e-45 yjgA - - T - - - Protein of unknown function (DUF2809)
MDCBHCFC_01775 1.93e-211 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
MDCBHCFC_01776 1.13e-29 yjfB - - S - - - Putative motility protein
MDCBHCFC_01777 8.68e-106 - - - S - - - Protein of unknown function (DUF2690)
MDCBHCFC_01778 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
MDCBHCFC_01780 8.79e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MDCBHCFC_01781 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
MDCBHCFC_01782 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
MDCBHCFC_01783 1.18e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDCBHCFC_01785 8.85e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MDCBHCFC_01786 1.31e-75 yjdF3 - - S - - - Protein of unknown function (DUF2992)
MDCBHCFC_01787 1.7e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MDCBHCFC_01788 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_01789 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
MDCBHCFC_01790 8.47e-59 yjcN - - - - - - -
MDCBHCFC_01791 3.65e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
MDCBHCFC_01792 8.12e-225 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MDCBHCFC_01794 3.85e-10 - - - - - - - -
MDCBHCFC_01796 5.89e-18 - - - - - - - -
MDCBHCFC_01797 1.79e-23 - - - - - - - -
MDCBHCFC_01799 4.27e-273 yjcL - - S - - - Protein of unknown function (DUF819)
MDCBHCFC_01800 2.13e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
MDCBHCFC_01801 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MDCBHCFC_01802 8.05e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MDCBHCFC_01803 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
MDCBHCFC_01804 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
MDCBHCFC_01805 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDCBHCFC_01806 6.31e-51 - - - - - - - -
MDCBHCFC_01807 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MDCBHCFC_01808 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
MDCBHCFC_01811 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
MDCBHCFC_01812 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
MDCBHCFC_01813 1.08e-54 cotW - - - ko:K06341 - ko00000 -
MDCBHCFC_01814 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
MDCBHCFC_01815 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
MDCBHCFC_01816 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
MDCBHCFC_01817 1.71e-102 yjbX - - S - - - Spore coat protein
MDCBHCFC_01818 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MDCBHCFC_01819 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MDCBHCFC_01820 6.18e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MDCBHCFC_01821 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MDCBHCFC_01822 8.9e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
MDCBHCFC_01823 4.44e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
MDCBHCFC_01824 5.47e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
MDCBHCFC_01825 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MDCBHCFC_01826 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MDCBHCFC_01827 3.3e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MDCBHCFC_01828 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MDCBHCFC_01829 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDCBHCFC_01830 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
MDCBHCFC_01831 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
MDCBHCFC_01832 7.32e-130 yjbK - - S - - - protein conserved in bacteria
MDCBHCFC_01833 2.8e-126 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MDCBHCFC_01834 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
MDCBHCFC_01835 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MDCBHCFC_01836 2.68e-28 - - - - - - - -
MDCBHCFC_01837 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MDCBHCFC_01838 1.71e-279 coiA - - S ko:K06198 - ko00000 Competence protein
MDCBHCFC_01839 6.89e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MDCBHCFC_01840 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
MDCBHCFC_01841 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDCBHCFC_01842 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDCBHCFC_01843 9.6e-260 yjbB - - EGP - - - Major Facilitator Superfamily
MDCBHCFC_01844 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDCBHCFC_01845 1.37e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDCBHCFC_01846 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDCBHCFC_01847 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDCBHCFC_01848 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDCBHCFC_01849 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
MDCBHCFC_01850 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
MDCBHCFC_01851 1.48e-197 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDCBHCFC_01852 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDCBHCFC_01853 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
MDCBHCFC_01854 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDCBHCFC_01855 1.76e-233 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDCBHCFC_01856 9.1e-191 yjaZ - - O - - - Zn-dependent protease
MDCBHCFC_01857 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDCBHCFC_01858 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDCBHCFC_01859 3.48e-33 yjzB - - - - - - -
MDCBHCFC_01860 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
MDCBHCFC_01861 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
MDCBHCFC_01862 3.52e-130 yjaV - - - - - - -
MDCBHCFC_01863 1.4e-181 yjaU - - I - - - carboxylic ester hydrolase activity
MDCBHCFC_01864 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
MDCBHCFC_01865 2.51e-39 yjzC - - S - - - YjzC-like protein
MDCBHCFC_01866 2.47e-224 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDCBHCFC_01867 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
MDCBHCFC_01868 1.15e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MDCBHCFC_01869 9.37e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
MDCBHCFC_01870 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MDCBHCFC_01871 4.1e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MDCBHCFC_01872 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MDCBHCFC_01873 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
MDCBHCFC_01874 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
MDCBHCFC_01875 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
MDCBHCFC_01876 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
MDCBHCFC_01877 5.9e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MDCBHCFC_01878 6.18e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MDCBHCFC_01879 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
MDCBHCFC_01880 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
MDCBHCFC_01881 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MDCBHCFC_01882 2.15e-200 yitS - - S - - - protein conserved in bacteria
MDCBHCFC_01883 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
MDCBHCFC_01884 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
MDCBHCFC_01885 5.86e-118 - - - - - - - -
MDCBHCFC_01886 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
MDCBHCFC_01887 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
MDCBHCFC_01888 2.87e-218 - - - - - - - -
MDCBHCFC_01889 4.16e-122 - - - - - - - -
MDCBHCFC_01890 3.08e-201 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
MDCBHCFC_01891 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
MDCBHCFC_01892 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MDCBHCFC_01893 2.16e-93 - - - S - - - Acetyltransferase (GNAT) domain
MDCBHCFC_01894 1.5e-195 yitH - - K - - - Acetyltransferase (GNAT) domain
MDCBHCFC_01895 8.28e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_01896 1.19e-280 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MDCBHCFC_01897 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDCBHCFC_01898 7.15e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
MDCBHCFC_01899 4.62e-154 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
MDCBHCFC_01900 6.43e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
MDCBHCFC_01901 7.62e-293 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
MDCBHCFC_01902 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MDCBHCFC_01903 1.85e-198 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MDCBHCFC_01904 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
MDCBHCFC_01905 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDCBHCFC_01906 2.37e-134 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
MDCBHCFC_01907 1.65e-118 yisT - - S - - - DinB family
MDCBHCFC_01908 4.25e-248 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MDCBHCFC_01909 1.06e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDCBHCFC_01910 1.41e-207 yisR - - K - - - Transcriptional regulator
MDCBHCFC_01911 1.01e-310 yisQ - - V - - - Mate efflux family protein
MDCBHCFC_01912 1.72e-186 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
MDCBHCFC_01913 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
MDCBHCFC_01914 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MDCBHCFC_01915 2.49e-130 yisN - - S - - - Protein of unknown function (DUF2777)
MDCBHCFC_01916 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MDCBHCFC_01917 5.88e-74 yisL - - S - - - UPF0344 protein
MDCBHCFC_01918 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MDCBHCFC_01919 2.11e-219 cotH - - M ko:K06330 - ko00000 Spore Coat
MDCBHCFC_01920 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
MDCBHCFC_01921 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
MDCBHCFC_01922 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
MDCBHCFC_01923 3.34e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
MDCBHCFC_01924 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
MDCBHCFC_01925 1.53e-83 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
MDCBHCFC_01926 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
MDCBHCFC_01927 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
MDCBHCFC_01928 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
MDCBHCFC_01929 1.4e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MDCBHCFC_01930 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MDCBHCFC_01931 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
MDCBHCFC_01932 2.19e-100 yhjR - - S - - - Rubrerythrin
MDCBHCFC_01933 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
MDCBHCFC_01934 1.45e-262 - - - EGP - - - Transmembrane secretion effector
MDCBHCFC_01935 2.05e-258 yhjN - - S ko:K07120 - ko00000 membrane
MDCBHCFC_01936 5.09e-238 yhjM - - K - - - Transcriptional regulator
MDCBHCFC_01937 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MDCBHCFC_01938 5.31e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
MDCBHCFC_01939 4.46e-254 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MDCBHCFC_01940 7.37e-271 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
MDCBHCFC_01943 3.29e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDCBHCFC_01944 0.0 yhjG - - CH - - - FAD binding domain
MDCBHCFC_01945 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MDCBHCFC_01946 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
MDCBHCFC_01947 8.34e-78 yhjD - - - - - - -
MDCBHCFC_01948 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
MDCBHCFC_01949 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDCBHCFC_01950 2.04e-56 yhjA - - S - - - Excalibur calcium-binding domain
MDCBHCFC_01951 1.04e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MDCBHCFC_01952 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
MDCBHCFC_01953 9.84e-45 yhzC - - S - - - IDEAL
MDCBHCFC_01954 2.24e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_01955 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
MDCBHCFC_01956 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
MDCBHCFC_01957 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MDCBHCFC_01958 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MDCBHCFC_01959 4.25e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MDCBHCFC_01960 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
MDCBHCFC_01961 9.26e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MDCBHCFC_01962 8.03e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
MDCBHCFC_01963 3.6e-101 - - - K - - - acetyltransferase
MDCBHCFC_01964 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MDCBHCFC_01965 1.08e-304 yhfN - - O - - - Peptidase M48
MDCBHCFC_01966 2.28e-84 yhfM - - - - - - -
MDCBHCFC_01967 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
MDCBHCFC_01968 8.67e-143 yhfK - - GM - - - NmrA-like family
MDCBHCFC_01969 1.66e-244 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MDCBHCFC_01970 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MDCBHCFC_01971 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDCBHCFC_01972 1.79e-92 - - - S - - - ASCH
MDCBHCFC_01973 1.27e-251 yhfE - - G - - - peptidase M42
MDCBHCFC_01974 3.8e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
MDCBHCFC_01975 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDCBHCFC_01976 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
MDCBHCFC_01977 8.23e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_01978 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MDCBHCFC_01979 3.82e-228 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MDCBHCFC_01980 2.14e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MDCBHCFC_01981 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MDCBHCFC_01982 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MDCBHCFC_01983 2.36e-43 - - - C - - - Rubrerythrin
MDCBHCFC_01984 1.56e-311 yhfA - - C - - - membrane
MDCBHCFC_01985 6.27e-291 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MDCBHCFC_01986 3.78e-157 ecsC - - S - - - EcsC protein family
MDCBHCFC_01987 7.32e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MDCBHCFC_01988 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
MDCBHCFC_01989 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MDCBHCFC_01990 2.15e-261 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MDCBHCFC_01991 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
MDCBHCFC_01992 9.66e-30 - - - - - - - -
MDCBHCFC_01993 3.89e-54 yhaH - - S - - - YtxH-like protein
MDCBHCFC_01994 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
MDCBHCFC_01995 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
MDCBHCFC_01996 1.4e-116 yhaK - - S - - - Putative zincin peptidase
MDCBHCFC_01997 2.14e-170 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDCBHCFC_01998 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
MDCBHCFC_01999 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
MDCBHCFC_02000 0.0 yhaN - - L - - - AAA domain
MDCBHCFC_02001 9.44e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
MDCBHCFC_02002 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
MDCBHCFC_02003 4.57e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_02004 5.43e-35 - - - S - - - YhzD-like protein
MDCBHCFC_02005 1.79e-169 yhaR - - I - - - enoyl-CoA hydratase
MDCBHCFC_02007 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
MDCBHCFC_02008 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
MDCBHCFC_02009 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
MDCBHCFC_02010 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
MDCBHCFC_02011 2.15e-260 yhaZ - - L - - - DNA alkylation repair enzyme
MDCBHCFC_02012 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
MDCBHCFC_02013 7.19e-260 yheB - - S - - - Belongs to the UPF0754 family
MDCBHCFC_02014 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
MDCBHCFC_02015 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
MDCBHCFC_02016 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
MDCBHCFC_02017 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
MDCBHCFC_02018 9.1e-141 yheG - - GM - - - NAD(P)H-binding
MDCBHCFC_02019 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MDCBHCFC_02020 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MDCBHCFC_02021 4.38e-108 nhaX - - T - - - Belongs to the universal stress protein A family
MDCBHCFC_02022 1.99e-300 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
MDCBHCFC_02023 7.45e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MDCBHCFC_02024 3.54e-194 nodB1 - - G - - - deacetylase
MDCBHCFC_02025 1.98e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MDCBHCFC_02026 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
MDCBHCFC_02027 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
MDCBHCFC_02028 5.23e-172 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MDCBHCFC_02029 1.67e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDCBHCFC_02030 5.01e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDCBHCFC_02031 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
MDCBHCFC_02032 2.95e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MDCBHCFC_02033 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
MDCBHCFC_02034 3.22e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MDCBHCFC_02035 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MDCBHCFC_02036 6.74e-244 yhdN - - C - - - Aldo keto reductase
MDCBHCFC_02037 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_02038 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
MDCBHCFC_02039 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
MDCBHCFC_02040 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDCBHCFC_02041 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDCBHCFC_02042 2.04e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MDCBHCFC_02043 7.15e-316 yhdG - - E ko:K03294 - ko00000 amino acid
MDCBHCFC_02044 4.53e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_02045 7.18e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
MDCBHCFC_02046 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_02047 1.45e-203 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MDCBHCFC_02048 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MDCBHCFC_02049 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
MDCBHCFC_02050 1.44e-304 ygxB - - M - - - Conserved TM helix
MDCBHCFC_02051 1.95e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
MDCBHCFC_02052 2.79e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
MDCBHCFC_02053 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
MDCBHCFC_02054 1.65e-51 yhdB - - S - - - YhdB-like protein
MDCBHCFC_02055 1.63e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
MDCBHCFC_02056 7.73e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDCBHCFC_02057 6.28e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_02058 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
MDCBHCFC_02059 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MDCBHCFC_02060 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDCBHCFC_02061 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MDCBHCFC_02062 6.25e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MDCBHCFC_02063 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDCBHCFC_02064 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MDCBHCFC_02065 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
MDCBHCFC_02066 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
MDCBHCFC_02067 2.03e-87 yhcU - - S - - - Family of unknown function (DUF5365)
MDCBHCFC_02068 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MDCBHCFC_02069 3.07e-133 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
MDCBHCFC_02070 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MDCBHCFC_02071 2.39e-146 yhcQ - - M - - - Spore coat protein
MDCBHCFC_02072 5.17e-223 yhcP - - - - - - -
MDCBHCFC_02073 9.32e-108 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDCBHCFC_02074 1.09e-61 yhcM - - - - - - -
MDCBHCFC_02075 3.22e-65 - - - K - - - Transcriptional regulator PadR-like family
MDCBHCFC_02076 1.19e-114 - - - S - - - Protein of unknown function (DUF2812)
MDCBHCFC_02077 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDCBHCFC_02078 3.36e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
MDCBHCFC_02079 1.06e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MDCBHCFC_02080 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
MDCBHCFC_02081 9.87e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDCBHCFC_02082 3.59e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_02083 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_02084 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_02085 2.92e-69 - - - - - - - -
MDCBHCFC_02086 3.95e-59 yhcC - - - - - - -
MDCBHCFC_02087 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
MDCBHCFC_02088 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MDCBHCFC_02089 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
MDCBHCFC_02090 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
MDCBHCFC_02091 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
MDCBHCFC_02092 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
MDCBHCFC_02093 2.34e-102 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MDCBHCFC_02094 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
MDCBHCFC_02095 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
MDCBHCFC_02096 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDCBHCFC_02097 4.79e-226 yhbB - - S - - - Putative amidase domain
MDCBHCFC_02098 3.44e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MDCBHCFC_02099 6.43e-146 yhzB - - S - - - B3/4 domain
MDCBHCFC_02101 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_02102 5.19e-98 ygaO - - - - - - -
MDCBHCFC_02103 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDCBHCFC_02105 1.55e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
MDCBHCFC_02106 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MDCBHCFC_02107 4.19e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
MDCBHCFC_02108 2.58e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MDCBHCFC_02109 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MDCBHCFC_02111 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MDCBHCFC_02112 2.06e-165 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MDCBHCFC_02113 1.58e-36 - - - - - - - -
MDCBHCFC_02114 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
MDCBHCFC_02115 7.75e-14 - - - - - - - -
MDCBHCFC_02118 1.83e-94 - - - J - - - tRNA cytidylyltransferase activity
MDCBHCFC_02130 3.91e-99 - - - L - - - Integrase
MDCBHCFC_02131 3.5e-257 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
MDCBHCFC_02132 5.02e-139 - - - L - - - ApaLI-like restriction endonuclease
MDCBHCFC_02133 1.68e-179 - - - L - - - Phage integrase family
MDCBHCFC_02156 7.33e-83 galE1 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MDCBHCFC_02157 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDCBHCFC_02158 7.19e-94 ywhA - - K - - - Transcriptional regulator
MDCBHCFC_02159 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
MDCBHCFC_02160 3.29e-154 ywhC - - S - - - Peptidase family M50
MDCBHCFC_02161 4.53e-122 ywhD - - S - - - YwhD family
MDCBHCFC_02162 2.1e-64 - - - - - - - -
MDCBHCFC_02163 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MDCBHCFC_02164 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MDCBHCFC_02165 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MDCBHCFC_02167 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDCBHCFC_02170 1.3e-10 - - - - - - - -
MDCBHCFC_02173 9.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MDCBHCFC_02174 5.47e-274 ywhK - - CO - - - amine dehydrogenase activity
MDCBHCFC_02175 9.89e-315 ywhL - - CO - - - amine dehydrogenase activity
MDCBHCFC_02177 3.9e-316 - - - L - - - Peptidase, M16
MDCBHCFC_02178 3.29e-274 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
MDCBHCFC_02179 7.21e-299 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
MDCBHCFC_02180 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MDCBHCFC_02182 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
MDCBHCFC_02183 3.71e-12 - - - S - - - Bacteriocin subtilosin A
MDCBHCFC_02184 4.64e-96 ywiB - - S - - - protein conserved in bacteria
MDCBHCFC_02185 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MDCBHCFC_02186 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MDCBHCFC_02187 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
MDCBHCFC_02188 2.15e-178 ywiC - - S - - - YwiC-like protein
MDCBHCFC_02189 3.53e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
MDCBHCFC_02190 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDCBHCFC_02191 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
MDCBHCFC_02192 1.6e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
MDCBHCFC_02193 4.16e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
MDCBHCFC_02194 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDCBHCFC_02195 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MDCBHCFC_02196 1.31e-73 ywjB - - H - - - RibD C-terminal domain
MDCBHCFC_02197 1.92e-32 ywjB - - H - - - RibD C-terminal domain
MDCBHCFC_02198 1.32e-57 ywjC - - - - - - -
MDCBHCFC_02199 8.09e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MDCBHCFC_02200 5.31e-284 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MDCBHCFC_02201 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
MDCBHCFC_02202 1.21e-268 acdA - - I - - - acyl-CoA dehydrogenase
MDCBHCFC_02203 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDCBHCFC_02204 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDCBHCFC_02205 2.24e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
MDCBHCFC_02206 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
MDCBHCFC_02207 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
MDCBHCFC_02208 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MDCBHCFC_02209 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDCBHCFC_02210 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
MDCBHCFC_02211 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MDCBHCFC_02212 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
MDCBHCFC_02213 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MDCBHCFC_02214 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
MDCBHCFC_02215 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MDCBHCFC_02216 2.93e-108 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MDCBHCFC_02217 4.84e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDCBHCFC_02218 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDCBHCFC_02219 8.46e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDCBHCFC_02221 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
MDCBHCFC_02222 9.35e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
MDCBHCFC_02223 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
MDCBHCFC_02224 7.37e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDCBHCFC_02225 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
MDCBHCFC_02226 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDCBHCFC_02227 9.5e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
MDCBHCFC_02228 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
MDCBHCFC_02229 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDCBHCFC_02230 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDCBHCFC_02231 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
MDCBHCFC_02232 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MDCBHCFC_02233 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDCBHCFC_02234 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDCBHCFC_02235 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDCBHCFC_02236 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDCBHCFC_02237 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDCBHCFC_02238 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDCBHCFC_02239 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MDCBHCFC_02240 6.12e-115 ywmA - - - - - - -
MDCBHCFC_02241 4.54e-45 ywzB - - S - - - membrane
MDCBHCFC_02242 1.97e-173 ywmB - - S - - - TATA-box binding
MDCBHCFC_02243 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDCBHCFC_02244 6.88e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
MDCBHCFC_02245 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MDCBHCFC_02246 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MDCBHCFC_02248 1.5e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MDCBHCFC_02249 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MDCBHCFC_02250 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MDCBHCFC_02251 1.72e-109 ywmF - - S - - - Peptidase M50
MDCBHCFC_02252 1.11e-21 csbD - - K - - - CsbD-like
MDCBHCFC_02253 2.17e-30 - - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MDCBHCFC_02254 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
MDCBHCFC_02255 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
MDCBHCFC_02256 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MDCBHCFC_02257 4.58e-85 ywnA - - K - - - Transcriptional regulator
MDCBHCFC_02258 2.06e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
MDCBHCFC_02259 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
MDCBHCFC_02260 1.14e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
MDCBHCFC_02261 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDCBHCFC_02262 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
MDCBHCFC_02263 6.55e-22 ywnC - - S - - - Family of unknown function (DUF5362)
MDCBHCFC_02264 1.49e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
MDCBHCFC_02265 2.63e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
MDCBHCFC_02266 7.75e-94 ywnJ - - S - - - VanZ like family
MDCBHCFC_02267 1.21e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
MDCBHCFC_02268 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
MDCBHCFC_02269 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
MDCBHCFC_02270 9.77e-101 - - - - - - - -
MDCBHCFC_02271 2.56e-134 yjgF - - Q - - - Isochorismatase family
MDCBHCFC_02272 1.09e-306 ywoD - - EGP - - - Major facilitator superfamily
MDCBHCFC_02273 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
MDCBHCFC_02274 1.88e-308 ywoF - - P - - - Right handed beta helix region
MDCBHCFC_02275 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_02276 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
MDCBHCFC_02277 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
MDCBHCFC_02278 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
MDCBHCFC_02279 5.66e-169 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MDCBHCFC_02280 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
MDCBHCFC_02281 7.42e-255 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
MDCBHCFC_02282 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MDCBHCFC_02283 5.62e-78 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDCBHCFC_02284 0.0 ywpD - - T - - - Histidine kinase
MDCBHCFC_02285 1.68e-221 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
MDCBHCFC_02286 0.0 - - - M - - - cell wall anchor domain
MDCBHCFC_02287 7.14e-108 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MDCBHCFC_02288 8.81e-89 ywpF - - S - - - YwpF-like protein
MDCBHCFC_02289 5.26e-88 ywpG - - - - - - -
MDCBHCFC_02290 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MDCBHCFC_02291 2.79e-179 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MDCBHCFC_02292 2.62e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MDCBHCFC_02293 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
MDCBHCFC_02294 0.0 ywqB - - S - - - SWIM zinc finger
MDCBHCFC_02295 3.6e-25 - - - - - - - -
MDCBHCFC_02296 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
MDCBHCFC_02297 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MDCBHCFC_02298 1.44e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
MDCBHCFC_02299 5.43e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDCBHCFC_02300 7.24e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
MDCBHCFC_02302 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
MDCBHCFC_02303 1.77e-313 ywqJ - - S - - - Pre-toxin TG
MDCBHCFC_02304 1.01e-61 - - - - - - - -
MDCBHCFC_02305 1.32e-65 - - - - - - - -
MDCBHCFC_02307 2.77e-125 - - - - - - - -
MDCBHCFC_02308 9.69e-95 - - - - - - - -
MDCBHCFC_02309 4.92e-154 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MDCBHCFC_02310 3.33e-209 - - - K - - - Transcriptional regulator
MDCBHCFC_02311 5.23e-130 ywqN - - S - - - NAD(P)H-dependent
MDCBHCFC_02313 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
MDCBHCFC_02314 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
MDCBHCFC_02315 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MDCBHCFC_02316 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
MDCBHCFC_02317 5.61e-71 - - - S - - - Domain of unknown function (DUF4181)
MDCBHCFC_02318 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MDCBHCFC_02319 1.03e-17 - - - - - - - -
MDCBHCFC_02320 2.08e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
MDCBHCFC_02321 5.28e-174 cotB - - - ko:K06325 - ko00000 -
MDCBHCFC_02322 3.04e-162 ywrJ - - - - - - -
MDCBHCFC_02323 1.32e-278 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MDCBHCFC_02324 3.36e-218 alsR - - K - - - LysR substrate binding domain
MDCBHCFC_02325 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MDCBHCFC_02326 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MDCBHCFC_02327 3.57e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
MDCBHCFC_02328 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
MDCBHCFC_02329 4.83e-120 batE - - T - - - Sh3 type 3 domain protein
MDCBHCFC_02330 3.68e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
MDCBHCFC_02331 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDCBHCFC_02332 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MDCBHCFC_02333 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDCBHCFC_02334 4.17e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDCBHCFC_02335 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
MDCBHCFC_02336 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
MDCBHCFC_02337 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
MDCBHCFC_02338 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MDCBHCFC_02339 2.29e-29 ywtC - - - - - - -
MDCBHCFC_02340 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MDCBHCFC_02341 5.95e-204 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
MDCBHCFC_02342 1.84e-180 ywtF_2 - - K - - - Transcriptional regulator
MDCBHCFC_02343 9.1e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDCBHCFC_02344 2.75e-267 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
MDCBHCFC_02345 1.09e-250 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MDCBHCFC_02346 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MDCBHCFC_02347 2.62e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MDCBHCFC_02348 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDCBHCFC_02349 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDCBHCFC_02350 1.34e-109 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDCBHCFC_02351 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MDCBHCFC_02352 1.46e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MDCBHCFC_02353 5.02e-130 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDCBHCFC_02354 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDCBHCFC_02355 2.29e-74 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
MDCBHCFC_02356 1.2e-170 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MDCBHCFC_02357 4.41e-305 - - - M - - - Glycosyltransferase like family 2
MDCBHCFC_02358 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDCBHCFC_02359 1.67e-168 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MDCBHCFC_02360 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MDCBHCFC_02361 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MDCBHCFC_02363 6.09e-119 - - - M - - - Glycosyl transferases group 1
MDCBHCFC_02364 2.07e-103 - - - M - - - Glycosyltransferase like family 2
MDCBHCFC_02365 2.03e-272 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDCBHCFC_02366 2.34e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MDCBHCFC_02367 4.58e-16 - - - - - - - -
MDCBHCFC_02368 0.0 lytB - - D - - - Stage II sporulation protein
MDCBHCFC_02369 1.01e-261 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MDCBHCFC_02370 1.78e-108 - - - M - - - Glycosyltransferase like family 2
MDCBHCFC_02371 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MDCBHCFC_02372 3.44e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDCBHCFC_02373 4.86e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
MDCBHCFC_02374 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MDCBHCFC_02375 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
MDCBHCFC_02376 2.02e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
MDCBHCFC_02377 2.41e-186 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MDCBHCFC_02378 1.61e-294 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
MDCBHCFC_02379 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MDCBHCFC_02380 5.23e-224 yvhJ - - K - - - Transcriptional regulator
MDCBHCFC_02381 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
MDCBHCFC_02382 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MDCBHCFC_02383 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDCBHCFC_02384 4.34e-199 degV - - S - - - protein conserved in bacteria
MDCBHCFC_02385 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MDCBHCFC_02386 4.22e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
MDCBHCFC_02387 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
MDCBHCFC_02388 1.83e-96 yvyF - - S - - - flagellar protein
MDCBHCFC_02389 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
MDCBHCFC_02390 7.06e-102 yvyG - - NOU - - - FlgN protein
MDCBHCFC_02391 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
MDCBHCFC_02392 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
MDCBHCFC_02393 6.92e-92 yviE - - - - - - -
MDCBHCFC_02394 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MDCBHCFC_02395 3.02e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MDCBHCFC_02396 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MDCBHCFC_02397 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
MDCBHCFC_02398 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MDCBHCFC_02399 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
MDCBHCFC_02400 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
MDCBHCFC_02401 7.52e-87 - - - - - - - -
MDCBHCFC_02402 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDCBHCFC_02403 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDCBHCFC_02404 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDCBHCFC_02405 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MDCBHCFC_02406 4.42e-73 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
MDCBHCFC_02407 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
MDCBHCFC_02408 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MDCBHCFC_02409 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MDCBHCFC_02410 1.38e-73 swrA - - S - - - Swarming motility protein
MDCBHCFC_02411 2.6e-279 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDCBHCFC_02412 1.23e-294 yvkA - - P - - - -transporter
MDCBHCFC_02413 1.43e-131 yvkB - - K - - - Transcriptional regulator
MDCBHCFC_02414 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
MDCBHCFC_02415 2.54e-42 csbA - - S - - - protein conserved in bacteria
MDCBHCFC_02416 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDCBHCFC_02417 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDCBHCFC_02418 2.33e-77 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MDCBHCFC_02419 2.25e-45 yvkN - - - - - - -
MDCBHCFC_02420 3.3e-64 yvlA - - - - - - -
MDCBHCFC_02421 1.36e-219 yvlB - - S - - - Putative adhesin
MDCBHCFC_02422 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MDCBHCFC_02423 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
MDCBHCFC_02424 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
MDCBHCFC_02425 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDCBHCFC_02426 8.35e-176 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MDCBHCFC_02427 2.45e-288 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
MDCBHCFC_02428 4.06e-94 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDCBHCFC_02429 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
MDCBHCFC_02430 2.48e-170 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
MDCBHCFC_02431 4.1e-164 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDCBHCFC_02432 9.81e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDCBHCFC_02433 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDCBHCFC_02434 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDCBHCFC_02435 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
MDCBHCFC_02436 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MDCBHCFC_02437 3.58e-119 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MDCBHCFC_02438 1.05e-151 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
MDCBHCFC_02439 6.12e-179 yvpB - - NU - - - protein conserved in bacteria
MDCBHCFC_02440 9.84e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MDCBHCFC_02441 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MDCBHCFC_02442 7.38e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MDCBHCFC_02443 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MDCBHCFC_02444 8.08e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MDCBHCFC_02445 8.92e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MDCBHCFC_02446 9.34e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MDCBHCFC_02447 4.86e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
MDCBHCFC_02448 3.7e-111 - - - - - - - -
MDCBHCFC_02449 0.0 - - - - - - - -
MDCBHCFC_02451 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MDCBHCFC_02452 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
MDCBHCFC_02453 2.68e-185 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
MDCBHCFC_02454 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDCBHCFC_02455 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MDCBHCFC_02456 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MDCBHCFC_02457 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MDCBHCFC_02458 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MDCBHCFC_02459 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
MDCBHCFC_02460 8.98e-180 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
MDCBHCFC_02461 1.55e-42 - - - - - - - -
MDCBHCFC_02462 3.84e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_02463 2.28e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
MDCBHCFC_02464 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_02465 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MDCBHCFC_02466 2.7e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDCBHCFC_02467 8.79e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
MDCBHCFC_02468 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MDCBHCFC_02469 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
MDCBHCFC_02470 5.37e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MDCBHCFC_02471 1.54e-221 yvdE - - K - - - Transcriptional regulator
MDCBHCFC_02472 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
MDCBHCFC_02473 2.42e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
MDCBHCFC_02474 3.37e-308 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
MDCBHCFC_02475 1.96e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
MDCBHCFC_02476 3.16e-199 malA - - S - - - Protein of unknown function (DUF1189)
MDCBHCFC_02477 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
MDCBHCFC_02478 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MDCBHCFC_02479 1.53e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MDCBHCFC_02480 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDCBHCFC_02482 1.12e-121 yvdQ - - S - - - Protein of unknown function (DUF3231)
MDCBHCFC_02483 1.47e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
MDCBHCFC_02484 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
MDCBHCFC_02485 5.56e-136 yvdT_1 - - K - - - Transcriptional regulator
MDCBHCFC_02486 0.0 ybeC - - E - - - amino acid
MDCBHCFC_02487 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
MDCBHCFC_02488 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
MDCBHCFC_02489 4.82e-84 - - - - - - - -
MDCBHCFC_02490 0.0 pbpE - - V - - - Beta-lactamase
MDCBHCFC_02491 7.17e-162 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MDCBHCFC_02492 1.75e-93 - - - S - - - Protein of unknown function (DUF3237)
MDCBHCFC_02493 2.2e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MDCBHCFC_02495 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
MDCBHCFC_02496 1.24e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
MDCBHCFC_02497 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
MDCBHCFC_02498 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
MDCBHCFC_02499 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
MDCBHCFC_02500 7.45e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
MDCBHCFC_02501 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
MDCBHCFC_02502 1.28e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MDCBHCFC_02503 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
MDCBHCFC_02504 6.04e-249 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MDCBHCFC_02505 7.76e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
MDCBHCFC_02506 1.12e-244 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MDCBHCFC_02507 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDCBHCFC_02508 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MDCBHCFC_02509 4.72e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
MDCBHCFC_02510 6.85e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
MDCBHCFC_02511 2.83e-236 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
MDCBHCFC_02512 5.69e-44 yvfG - - S - - - YvfG protein
MDCBHCFC_02513 4.96e-306 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MDCBHCFC_02514 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MDCBHCFC_02515 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
MDCBHCFC_02516 6.96e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_02517 1.55e-290 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
MDCBHCFC_02518 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
MDCBHCFC_02519 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
MDCBHCFC_02520 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
MDCBHCFC_02521 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
MDCBHCFC_02522 5.07e-264 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
MDCBHCFC_02523 1.46e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
MDCBHCFC_02525 3.68e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
MDCBHCFC_02526 2.04e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MDCBHCFC_02527 5.51e-245 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_02528 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDCBHCFC_02529 2.6e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MDCBHCFC_02530 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MDCBHCFC_02531 8.03e-170 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MDCBHCFC_02532 2.02e-247 - - - S - - - Glycosyl hydrolase
MDCBHCFC_02533 1.17e-305 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MDCBHCFC_02534 1.6e-197 yvbV - - EG - - - EamA-like transporter family
MDCBHCFC_02535 1.4e-205 yvbU - - K - - - Transcriptional regulator
MDCBHCFC_02536 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDCBHCFC_02537 6.14e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
MDCBHCFC_02538 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDCBHCFC_02539 5.69e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MDCBHCFC_02540 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDCBHCFC_02541 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MDCBHCFC_02542 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDCBHCFC_02543 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
MDCBHCFC_02544 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDCBHCFC_02545 8.03e-105 yvbK - - K - - - acetyltransferase
MDCBHCFC_02546 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MDCBHCFC_02547 2.28e-156 yvbI - - M - - - Membrane
MDCBHCFC_02548 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
MDCBHCFC_02549 1.13e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
MDCBHCFC_02550 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MDCBHCFC_02551 3.23e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MDCBHCFC_02552 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MDCBHCFC_02553 2.48e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDCBHCFC_02554 5.59e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MDCBHCFC_02555 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
MDCBHCFC_02556 3.64e-271 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MDCBHCFC_02557 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MDCBHCFC_02558 7.93e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDCBHCFC_02559 2.48e-134 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
MDCBHCFC_02560 1.04e-231 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
MDCBHCFC_02561 8.57e-193 - - - V ko:K06147,ko:K06148,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
MDCBHCFC_02562 2.64e-96 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
MDCBHCFC_02565 7.1e-131 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_02566 1.67e-110 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MDCBHCFC_02567 1.49e-103 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MDCBHCFC_02568 1.41e-135 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MDCBHCFC_02569 1.43e-195 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MDCBHCFC_02570 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MDCBHCFC_02571 3.85e-72 yvaP - - K - - - transcriptional
MDCBHCFC_02572 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MDCBHCFC_02573 2.36e-91 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
MDCBHCFC_02574 4.9e-48 yvzC - - K - - - transcriptional
MDCBHCFC_02575 4.71e-195 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
MDCBHCFC_02576 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
MDCBHCFC_02577 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
MDCBHCFC_02578 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDCBHCFC_02579 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MDCBHCFC_02582 4.89e-22 - - - - - - - -
MDCBHCFC_02583 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_02584 5.77e-127 - - - K - - - Bacterial regulatory proteins, tetR family
MDCBHCFC_02585 2.38e-69 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MDCBHCFC_02586 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
MDCBHCFC_02587 0.0 - - - S - - - Fusaric acid resistance protein-like
MDCBHCFC_02588 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDCBHCFC_02589 1.71e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MDCBHCFC_02590 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
MDCBHCFC_02591 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
MDCBHCFC_02592 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MDCBHCFC_02593 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
MDCBHCFC_02594 3.45e-137 bdbD - - O - - - Thioredoxin
MDCBHCFC_02595 5.7e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
MDCBHCFC_02596 2.34e-139 yvgT - - S - - - membrane
MDCBHCFC_02598 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MDCBHCFC_02599 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MDCBHCFC_02600 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MDCBHCFC_02601 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
MDCBHCFC_02602 7.97e-113 yvgO - - - - - - -
MDCBHCFC_02603 6.19e-201 yvgN - - S - - - reductase
MDCBHCFC_02604 1.23e-153 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
MDCBHCFC_02605 8.57e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
MDCBHCFC_02606 2.97e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
MDCBHCFC_02607 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
MDCBHCFC_02608 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MDCBHCFC_02609 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
MDCBHCFC_02610 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
MDCBHCFC_02612 3.13e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDCBHCFC_02613 2.44e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_02614 9.64e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_02615 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MDCBHCFC_02616 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
MDCBHCFC_02617 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_02618 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
MDCBHCFC_02619 2.33e-84 yvrL - - S - - - Regulatory protein YrvL
MDCBHCFC_02620 3.09e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
MDCBHCFC_02621 3.46e-26 - - - S - - - YvrJ protein family
MDCBHCFC_02622 7.02e-128 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
MDCBHCFC_02623 5.07e-32 - - - - - - - -
MDCBHCFC_02624 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_02625 0.0 yvrG - - T - - - Histidine kinase
MDCBHCFC_02626 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
MDCBHCFC_02627 1.23e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_02628 2.98e-218 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MDCBHCFC_02629 1.9e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_02630 1.82e-309 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MDCBHCFC_02631 1.2e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
MDCBHCFC_02632 7.59e-287 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_02633 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
MDCBHCFC_02634 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MDCBHCFC_02635 6.28e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MDCBHCFC_02636 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MDCBHCFC_02637 4.74e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_02638 4.46e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDCBHCFC_02639 3.05e-243 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
MDCBHCFC_02640 3.94e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
MDCBHCFC_02641 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
MDCBHCFC_02642 2.6e-33 - - - S - - - Protein of unknown function (DUF3970)
MDCBHCFC_02643 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDCBHCFC_02644 3.06e-204 yuxN - - K - - - Transcriptional regulator
MDCBHCFC_02645 2.77e-316 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_02646 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_02647 1.12e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDCBHCFC_02648 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
MDCBHCFC_02649 3.54e-193 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_02650 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
MDCBHCFC_02651 3.48e-88 - - - S - - - YusW-like protein
MDCBHCFC_02652 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MDCBHCFC_02653 3.01e-63 yusU - - S - - - Protein of unknown function (DUF2573)
MDCBHCFC_02654 6.91e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
MDCBHCFC_02655 1.22e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_02656 1.7e-84 yusQ - - S - - - Tautomerase enzyme
MDCBHCFC_02657 0.0 yusP - - P - - - Major facilitator superfamily
MDCBHCFC_02658 1.82e-97 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
MDCBHCFC_02659 8.66e-70 yusN - - M - - - Coat F domain
MDCBHCFC_02660 2.23e-54 - - - - - - - -
MDCBHCFC_02661 8.15e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MDCBHCFC_02662 1.11e-13 - - - S - - - YuzL-like protein
MDCBHCFC_02663 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
MDCBHCFC_02664 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
MDCBHCFC_02665 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
MDCBHCFC_02666 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MDCBHCFC_02667 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MDCBHCFC_02668 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
MDCBHCFC_02669 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
MDCBHCFC_02670 8.14e-73 yusE - - CO - - - Thioredoxin
MDCBHCFC_02671 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
MDCBHCFC_02672 3.05e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDCBHCFC_02673 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
MDCBHCFC_02674 5.86e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
MDCBHCFC_02675 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MDCBHCFC_02676 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MDCBHCFC_02677 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
MDCBHCFC_02678 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDCBHCFC_02679 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
MDCBHCFC_02680 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
MDCBHCFC_02681 5.06e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDCBHCFC_02682 4.95e-51 - - - - - - - -
MDCBHCFC_02684 7.86e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
MDCBHCFC_02685 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
MDCBHCFC_02686 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MDCBHCFC_02687 4.07e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
MDCBHCFC_02688 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDCBHCFC_02689 2.27e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
MDCBHCFC_02690 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MDCBHCFC_02691 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MDCBHCFC_02692 1.15e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDCBHCFC_02693 7.63e-217 bsn - - L - - - Ribonuclease
MDCBHCFC_02694 8.34e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MDCBHCFC_02695 3.87e-302 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MDCBHCFC_02696 5.06e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MDCBHCFC_02697 7.22e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
MDCBHCFC_02698 7.39e-189 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MDCBHCFC_02699 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MDCBHCFC_02700 4.02e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MDCBHCFC_02701 0.000108 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MDCBHCFC_02702 1.72e-71 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MDCBHCFC_02703 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MDCBHCFC_02704 1.11e-283 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
MDCBHCFC_02705 1.55e-293 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
MDCBHCFC_02706 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
MDCBHCFC_02707 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MDCBHCFC_02708 3.06e-79 yunG - - - - - - -
MDCBHCFC_02709 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
MDCBHCFC_02710 7.59e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
MDCBHCFC_02711 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MDCBHCFC_02712 1.39e-64 yunC - - S - - - Domain of unknown function (DUF1805)
MDCBHCFC_02713 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
MDCBHCFC_02714 3.78e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
MDCBHCFC_02715 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MDCBHCFC_02716 3.16e-143 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MDCBHCFC_02717 3.2e-63 yutD - - S - - - protein conserved in bacteria
MDCBHCFC_02718 1.96e-98 yutE - - S - - - Protein of unknown function DUF86
MDCBHCFC_02719 2.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDCBHCFC_02720 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
MDCBHCFC_02721 1.74e-252 yutH - - S - - - Spore coat protein
MDCBHCFC_02722 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MDCBHCFC_02723 6.87e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MDCBHCFC_02724 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDCBHCFC_02725 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
MDCBHCFC_02726 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
MDCBHCFC_02727 2.7e-74 yuzD - - S - - - protein conserved in bacteria
MDCBHCFC_02728 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MDCBHCFC_02729 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
MDCBHCFC_02730 3.71e-217 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDCBHCFC_02731 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDCBHCFC_02732 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
MDCBHCFC_02733 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDCBHCFC_02734 2.34e-148 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
MDCBHCFC_02735 1.11e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDCBHCFC_02737 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
MDCBHCFC_02738 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MDCBHCFC_02739 3.98e-46 yuiB - - S - - - Putative membrane protein
MDCBHCFC_02740 1.5e-149 yuiC - - S - - - protein conserved in bacteria
MDCBHCFC_02741 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
MDCBHCFC_02742 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MDCBHCFC_02743 1.05e-278 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
MDCBHCFC_02744 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
MDCBHCFC_02745 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
MDCBHCFC_02746 8.58e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
MDCBHCFC_02747 2.89e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_02748 3.48e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
MDCBHCFC_02749 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
MDCBHCFC_02750 3.67e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
MDCBHCFC_02751 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCBHCFC_02752 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
MDCBHCFC_02753 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
MDCBHCFC_02754 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MDCBHCFC_02755 2.84e-290 yukF - - QT - - - Transcriptional regulator
MDCBHCFC_02756 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
MDCBHCFC_02757 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
MDCBHCFC_02758 8.62e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
MDCBHCFC_02759 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDCBHCFC_02760 0.0 yueB - - S - - - type VII secretion protein EsaA
MDCBHCFC_02761 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
MDCBHCFC_02762 6.83e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_02763 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
MDCBHCFC_02764 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
MDCBHCFC_02765 3.82e-91 - - - S - - - Protein of unknown function (DUF2283)
MDCBHCFC_02766 1.35e-244 yueF - - S - - - transporter activity
MDCBHCFC_02767 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
MDCBHCFC_02768 1.63e-52 yueH - - S - - - YueH-like protein
MDCBHCFC_02769 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
MDCBHCFC_02770 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
MDCBHCFC_02771 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDCBHCFC_02772 4.84e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
MDCBHCFC_02773 9.77e-08 yuzC - - - - - - -
MDCBHCFC_02774 6.29e-10 - - - S - - - DegQ (SacQ) family
MDCBHCFC_02775 7.01e-183 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
MDCBHCFC_02777 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_02778 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDCBHCFC_02779 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
MDCBHCFC_02780 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
MDCBHCFC_02781 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDCBHCFC_02782 6.08e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDCBHCFC_02783 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDCBHCFC_02784 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDCBHCFC_02785 3.12e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MDCBHCFC_02786 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MDCBHCFC_02787 1.73e-22 - - - - - - - -
MDCBHCFC_02788 9.31e-308 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
MDCBHCFC_02789 2.43e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDCBHCFC_02790 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDCBHCFC_02791 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_02792 4.33e-245 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
MDCBHCFC_02793 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MDCBHCFC_02794 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MDCBHCFC_02795 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
MDCBHCFC_02796 1.58e-96 yuxK - - S - - - protein conserved in bacteria
MDCBHCFC_02797 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
MDCBHCFC_02798 1.08e-242 yuxJ - - EGP - - - Major facilitator superfamily
MDCBHCFC_02800 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
MDCBHCFC_02801 2.49e-91 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
MDCBHCFC_02802 3.04e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_02803 5.74e-287 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MDCBHCFC_02804 1.58e-54 yugE - - S - - - Domain of unknown function (DUF1871)
MDCBHCFC_02805 2.33e-199 yugF - - I - - - Hydrolase
MDCBHCFC_02806 6.74e-112 alaR - - K - - - Transcriptional regulator
MDCBHCFC_02807 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
MDCBHCFC_02808 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MDCBHCFC_02809 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
MDCBHCFC_02810 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
MDCBHCFC_02811 9.22e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
MDCBHCFC_02812 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MDCBHCFC_02814 4.22e-95 yugN - - S - - - YugN-like family
MDCBHCFC_02815 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
MDCBHCFC_02816 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
MDCBHCFC_02817 1.58e-50 - - - - - - - -
MDCBHCFC_02818 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
MDCBHCFC_02819 8.8e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
MDCBHCFC_02820 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MDCBHCFC_02821 4.25e-94 yugU - - S - - - Uncharacterised protein family UPF0047
MDCBHCFC_02822 1.44e-47 - - - - - - - -
MDCBHCFC_02823 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MDCBHCFC_02824 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MDCBHCFC_02825 1.2e-297 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MDCBHCFC_02826 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MDCBHCFC_02827 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MDCBHCFC_02829 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
MDCBHCFC_02830 2.02e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MDCBHCFC_02831 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MDCBHCFC_02832 2.86e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
MDCBHCFC_02833 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
MDCBHCFC_02834 7.48e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MDCBHCFC_02835 8.95e-255 yubA - - S - - - transporter activity
MDCBHCFC_02836 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MDCBHCFC_02838 2.29e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
MDCBHCFC_02839 0.0 yubD - - P - - - Major Facilitator Superfamily
MDCBHCFC_02840 2.18e-195 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDCBHCFC_02841 3.31e-52 yubF - - S - - - yiaA/B two helix domain
MDCBHCFC_02842 8.78e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
MDCBHCFC_02843 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
MDCBHCFC_02844 5.83e-118 yuaB - - - - - - -
MDCBHCFC_02845 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
MDCBHCFC_02846 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MDCBHCFC_02847 1e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
MDCBHCFC_02848 5.8e-137 yuaD - - - - - - -
MDCBHCFC_02849 1.95e-109 yuaE - - S - - - DinB superfamily
MDCBHCFC_02850 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
MDCBHCFC_02851 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
MDCBHCFC_02852 9.48e-120 - - - M - - - FR47-like protein
MDCBHCFC_02853 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MDCBHCFC_02854 1.27e-34 - - - - - - - -
MDCBHCFC_02855 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
MDCBHCFC_02857 4.71e-203 ybaS - - S - - - Na -dependent transporter
MDCBHCFC_02858 1.89e-173 ybbA - - S ko:K07017 - ko00000 Putative esterase
MDCBHCFC_02859 8.27e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_02860 4.09e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_02861 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
MDCBHCFC_02862 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
MDCBHCFC_02863 6.68e-302 ybbC - - S - - - protein conserved in bacteria
MDCBHCFC_02864 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
MDCBHCFC_02865 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
MDCBHCFC_02866 5.99e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_02867 1.56e-193 ybbH - - K - - - transcriptional
MDCBHCFC_02868 9.51e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDCBHCFC_02869 5.2e-113 ybbJ - - J - - - acetyltransferase
MDCBHCFC_02870 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
MDCBHCFC_02876 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_02877 1.3e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MDCBHCFC_02878 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDCBHCFC_02879 3.55e-291 ybbR - - S - - - protein conserved in bacteria
MDCBHCFC_02880 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDCBHCFC_02881 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDCBHCFC_02882 2.28e-221 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MDCBHCFC_02883 1.64e-148 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
MDCBHCFC_02884 4.32e-126 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDCBHCFC_02885 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MDCBHCFC_02886 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
MDCBHCFC_02887 1.34e-118 ybcF - - P - - - carbonic anhydrase
MDCBHCFC_02888 1.6e-63 - - - - - - - -
MDCBHCFC_02889 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
MDCBHCFC_02890 9.45e-67 - - - K - - - Helix-turn-helix domain
MDCBHCFC_02891 1.89e-257 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
MDCBHCFC_02892 3.35e-73 - - - - - - - -
MDCBHCFC_02894 3.4e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
MDCBHCFC_02895 8.63e-192 ybdN - - - - - - -
MDCBHCFC_02896 1.49e-272 ybdO - - S - - - Domain of unknown function (DUF4885)
MDCBHCFC_02897 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MDCBHCFC_02898 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
MDCBHCFC_02899 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
MDCBHCFC_02900 3.56e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
MDCBHCFC_02901 3.12e-313 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
MDCBHCFC_02902 1.11e-54 ybyB - - - - - - -
MDCBHCFC_02903 0.0 ybeC - - E - - - amino acid
MDCBHCFC_02904 1.65e-209 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
MDCBHCFC_02905 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
MDCBHCFC_02906 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
MDCBHCFC_02907 1.22e-217 ybfA - - K - - - FR47-like protein
MDCBHCFC_02908 2.94e-80 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_02909 1.08e-182 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_02911 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
MDCBHCFC_02912 5.05e-206 ybfH - - EG - - - EamA-like transporter family
MDCBHCFC_02913 1.05e-187 ybfI - - K - - - AraC-like ligand binding domain
MDCBHCFC_02914 3.78e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MDCBHCFC_02915 4.14e-229 mpr - - M - - - Belongs to the peptidase S1B family
MDCBHCFC_02917 2.17e-211 - - - S - - - Alpha/beta hydrolase family
MDCBHCFC_02918 2.81e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDCBHCFC_02919 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
MDCBHCFC_02920 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MDCBHCFC_02921 1.58e-59 ybfN - - - - - - -
MDCBHCFC_02922 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
MDCBHCFC_02923 9.56e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
MDCBHCFC_02924 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDCBHCFC_02925 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_02926 1.28e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDCBHCFC_02927 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MDCBHCFC_02929 1.63e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MDCBHCFC_02930 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MDCBHCFC_02931 1.29e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
MDCBHCFC_02932 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
MDCBHCFC_02933 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MDCBHCFC_02934 2.05e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_02935 4.94e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
MDCBHCFC_02936 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
MDCBHCFC_02937 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDCBHCFC_02938 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_02939 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MDCBHCFC_02940 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
MDCBHCFC_02941 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
MDCBHCFC_02942 6.07e-223 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
MDCBHCFC_02943 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
MDCBHCFC_02944 1.41e-215 eamA1 - - EG - - - spore germination
MDCBHCFC_02945 1.84e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_02946 2.26e-216 ycbM - - T - - - Histidine kinase
MDCBHCFC_02947 1.86e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_02948 3.34e-147 - - - S - - - ABC-2 family transporter protein
MDCBHCFC_02949 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
MDCBHCFC_02950 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
MDCBHCFC_02951 2.7e-174 ycbR - - T - - - vWA found in TerF C terminus
MDCBHCFC_02952 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
MDCBHCFC_02953 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MDCBHCFC_02954 7.28e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MDCBHCFC_02955 2.82e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDCBHCFC_02956 5.08e-261 ycbU - - E - - - Selenocysteine lyase
MDCBHCFC_02957 1.24e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
MDCBHCFC_02958 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MDCBHCFC_02959 1.69e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MDCBHCFC_02960 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MDCBHCFC_02961 1.33e-72 - - - S - - - RDD family
MDCBHCFC_02962 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
MDCBHCFC_02963 2.87e-202 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MDCBHCFC_02964 6.58e-161 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MDCBHCFC_02965 8.97e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MDCBHCFC_02966 2.56e-253 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MDCBHCFC_02967 1.37e-221 yccK - - C - - - Aldo keto reductase
MDCBHCFC_02968 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
MDCBHCFC_02969 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_02970 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_02971 4.23e-120 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
MDCBHCFC_02972 6.72e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
MDCBHCFC_02973 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
MDCBHCFC_02974 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MDCBHCFC_02975 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MDCBHCFC_02976 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MDCBHCFC_02977 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MDCBHCFC_02978 6.65e-235 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDCBHCFC_02979 3.75e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
MDCBHCFC_02980 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MDCBHCFC_02981 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
MDCBHCFC_02982 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
MDCBHCFC_02983 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
MDCBHCFC_02984 2.96e-245 yceH - - P - - - Belongs to the TelA family
MDCBHCFC_02985 1.56e-277 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
MDCBHCFC_02986 3.98e-259 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
MDCBHCFC_02987 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MDCBHCFC_02988 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MDCBHCFC_02989 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MDCBHCFC_02990 1.65e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MDCBHCFC_02991 5.64e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
MDCBHCFC_02992 0.0 ycgA - - S - - - Membrane
MDCBHCFC_02993 2.72e-105 ycgB - - - - - - -
MDCBHCFC_02994 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
MDCBHCFC_02995 6.9e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MDCBHCFC_02996 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MDCBHCFC_02997 0.0 mdr - - EGP - - - the major facilitator superfamily
MDCBHCFC_02998 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDCBHCFC_02999 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
MDCBHCFC_03000 3.73e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
MDCBHCFC_03001 9.32e-317 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
MDCBHCFC_03002 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
MDCBHCFC_03003 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDCBHCFC_03004 5.13e-138 tmrB - - S - - - AAA domain
MDCBHCFC_03005 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MDCBHCFC_03006 1.24e-184 - - - Q - - - ubiE/COQ5 methyltransferase family
MDCBHCFC_03007 3.8e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
MDCBHCFC_03008 4.48e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
MDCBHCFC_03009 9.06e-186 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
MDCBHCFC_03010 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
MDCBHCFC_03011 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MDCBHCFC_03012 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDCBHCFC_03013 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
MDCBHCFC_03014 2.58e-193 ycgQ - - S ko:K08986 - ko00000 membrane
MDCBHCFC_03015 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
MDCBHCFC_03016 6.66e-200 ycgS - - I - - - alpha/beta hydrolase fold
MDCBHCFC_03017 5.52e-241 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MDCBHCFC_03018 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
MDCBHCFC_03019 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
MDCBHCFC_03020 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MDCBHCFC_03021 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDCBHCFC_03022 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
MDCBHCFC_03023 3.18e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
MDCBHCFC_03024 1.01e-220 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
MDCBHCFC_03025 1.22e-139 - - - M - - - ErfK YbiS YcfS YnhG
MDCBHCFC_03026 1.6e-289 yciC - - S - - - GTPases (G3E family)
MDCBHCFC_03027 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MDCBHCFC_03028 1.78e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MDCBHCFC_03030 2.43e-100 yckC - - S - - - membrane
MDCBHCFC_03031 3.53e-69 yckD - - S - - - Protein of unknown function (DUF2680)
MDCBHCFC_03032 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDCBHCFC_03033 1.37e-90 nin - - S - - - Competence protein J (ComJ)
MDCBHCFC_03034 4.6e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
MDCBHCFC_03035 7.13e-266 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
MDCBHCFC_03036 1.54e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MDCBHCFC_03037 9.74e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
MDCBHCFC_03038 6.05e-86 hxlR - - K - - - transcriptional
MDCBHCFC_03039 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCBHCFC_03040 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCBHCFC_03041 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
MDCBHCFC_03042 3.3e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
MDCBHCFC_03043 2.66e-289 - - - EGP - - - Major Facilitator Superfamily
MDCBHCFC_03044 1.8e-123 - - - S - - - YcxB-like protein
MDCBHCFC_03045 1.09e-203 ycxC - - EG - - - EamA-like transporter family
MDCBHCFC_03046 0.0 ycxD - - K - - - GntR family transcriptional regulator
MDCBHCFC_03047 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MDCBHCFC_03048 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
MDCBHCFC_03049 1.18e-170 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
MDCBHCFC_03050 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MDCBHCFC_03051 3.54e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MDCBHCFC_03052 3.08e-208 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
MDCBHCFC_03053 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MDCBHCFC_03054 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MDCBHCFC_03055 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
MDCBHCFC_03056 1.45e-107 yclD - - - - - - -
MDCBHCFC_03057 1.92e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
MDCBHCFC_03058 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
MDCBHCFC_03059 0.0 yclG - - M - - - Pectate lyase superfamily protein
MDCBHCFC_03061 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
MDCBHCFC_03062 3.21e-285 gerKC - - S ko:K06297 - ko00000 spore germination
MDCBHCFC_03063 1.93e-246 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
MDCBHCFC_03064 9.73e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MDCBHCFC_03065 3.17e-275 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
MDCBHCFC_03066 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_03067 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MDCBHCFC_03068 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
MDCBHCFC_03070 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MDCBHCFC_03071 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
MDCBHCFC_03072 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MDCBHCFC_03073 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_03074 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_03075 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_03076 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
MDCBHCFC_03077 0.0 ycnB - - EGP - - - the major facilitator superfamily
MDCBHCFC_03078 2.91e-198 ycnC - - K - - - Transcriptional regulator
MDCBHCFC_03079 8.65e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
MDCBHCFC_03080 1.68e-60 ycnE - - S - - - Monooxygenase
MDCBHCFC_03081 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MDCBHCFC_03082 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDCBHCFC_03083 5.18e-308 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDCBHCFC_03084 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDCBHCFC_03085 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
MDCBHCFC_03086 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_03087 3.99e-134 ycnI - - S - - - protein conserved in bacteria
MDCBHCFC_03088 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
MDCBHCFC_03089 4.09e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MDCBHCFC_03090 5.46e-74 - - - - - - - -
MDCBHCFC_03091 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
MDCBHCFC_03092 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MDCBHCFC_03093 8.87e-268 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
MDCBHCFC_03094 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
MDCBHCFC_03096 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MDCBHCFC_03097 9.52e-141 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
MDCBHCFC_03098 2.2e-86 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MDCBHCFC_03100 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MDCBHCFC_03101 4.46e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
MDCBHCFC_03102 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
MDCBHCFC_03103 4.54e-186 ycsI - - S - - - Belongs to the D-glutamate cyclase family
MDCBHCFC_03104 1.19e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
MDCBHCFC_03105 3.31e-237 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
MDCBHCFC_03106 1.55e-170 kipR - - K - - - Transcriptional regulator
MDCBHCFC_03107 1.83e-148 ycsK - - E - - - anatomical structure formation involved in morphogenesis
MDCBHCFC_03109 8.97e-65 yczJ - - S - - - biosynthesis
MDCBHCFC_03110 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
MDCBHCFC_03111 5.18e-221 ycsN - - S - - - Oxidoreductase
MDCBHCFC_03112 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
MDCBHCFC_03113 0.0 ydaB - - IQ - - - acyl-CoA ligase
MDCBHCFC_03114 8.87e-122 ydaC - - Q - - - Methyltransferase domain
MDCBHCFC_03115 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_03116 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MDCBHCFC_03117 1.1e-132 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MDCBHCFC_03118 1.06e-100 ydaG - - S - - - general stress protein
MDCBHCFC_03119 3.76e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MDCBHCFC_03120 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
MDCBHCFC_03121 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
MDCBHCFC_03122 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDCBHCFC_03123 8.48e-265 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MDCBHCFC_03124 4.65e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
MDCBHCFC_03125 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
MDCBHCFC_03126 1.12e-303 ydaM - - M - - - Glycosyl transferase family group 2
MDCBHCFC_03127 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
MDCBHCFC_03128 0.0 ydaO - - E - - - amino acid
MDCBHCFC_03129 7.28e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MDCBHCFC_03130 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MDCBHCFC_03131 1.45e-51 - - - - - - - -
MDCBHCFC_03132 1.59e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MDCBHCFC_03133 1.67e-42 ydaS - - S - - - membrane
MDCBHCFC_03134 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MDCBHCFC_03135 4.3e-190 ydbA - - P - - - EcsC protein family
MDCBHCFC_03136 3.3e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
MDCBHCFC_03137 7.58e-79 ydbB - - G - - - Cupin domain
MDCBHCFC_03138 5.41e-84 ydbC - - S - - - Domain of unknown function (DUF4937
MDCBHCFC_03139 6.41e-197 ydbD - - P ko:K07217 - ko00000 Catalase
MDCBHCFC_03140 8.63e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MDCBHCFC_03141 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MDCBHCFC_03142 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
MDCBHCFC_03143 1.27e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDCBHCFC_03144 1.32e-230 ydbI - - S - - - AI-2E family transporter
MDCBHCFC_03145 4.59e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_03146 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDCBHCFC_03147 9.32e-70 ydbL - - - - - - -
MDCBHCFC_03148 1.76e-278 ydbM - - I - - - acyl-CoA dehydrogenase
MDCBHCFC_03149 1.49e-26 - - - S - - - Fur-regulated basic protein B
MDCBHCFC_03150 2.1e-11 - - - S - - - Fur-regulated basic protein A
MDCBHCFC_03151 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDCBHCFC_03152 4.19e-75 ydbP - - CO - - - Thioredoxin
MDCBHCFC_03153 1.25e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MDCBHCFC_03154 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDCBHCFC_03155 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDCBHCFC_03156 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MDCBHCFC_03157 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
MDCBHCFC_03158 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
MDCBHCFC_03159 6.53e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDCBHCFC_03160 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
MDCBHCFC_03161 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDCBHCFC_03162 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MDCBHCFC_03163 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MDCBHCFC_03164 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
MDCBHCFC_03165 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
MDCBHCFC_03166 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MDCBHCFC_03167 8.83e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
MDCBHCFC_03168 3.98e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
MDCBHCFC_03169 8.3e-110 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MDCBHCFC_03170 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MDCBHCFC_03171 3.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
MDCBHCFC_03174 3.11e-105 ydcG - - S - - - EVE domain
MDCBHCFC_03175 1.79e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDCBHCFC_03176 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
MDCBHCFC_03177 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MDCBHCFC_03185 4.23e-09 - - - S - - - YvrJ protein family
MDCBHCFC_03186 2.99e-62 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MDCBHCFC_03190 3.29e-40 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
MDCBHCFC_03193 2.38e-26 - - - S - - - YesK-like protein
MDCBHCFC_03195 1.45e-86 - - - - - - - -
MDCBHCFC_03196 1.35e-264 ydcL - - L - - - Belongs to the 'phage' integrase family
MDCBHCFC_03197 7.82e-118 - - - E - - - Pfam:DUF955
MDCBHCFC_03198 1.51e-78 - - - K - - - Transcriptional
MDCBHCFC_03199 5.71e-48 - - - - - - - -
MDCBHCFC_03200 1.59e-45 - - - - - - - -
MDCBHCFC_03202 5.49e-85 - - - S - - - Bacterial protein of unknown function (DUF961)
MDCBHCFC_03203 3.37e-92 - - - - - - - -
MDCBHCFC_03204 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
MDCBHCFC_03205 1.45e-260 nicK - - L ko:K07467 - ko00000 Replication initiation factor
MDCBHCFC_03208 1.82e-65 yddA - - - - - - -
MDCBHCFC_03209 3.38e-219 yddB - - S - - - Conjugative transposon protein TcpC
MDCBHCFC_03210 2.81e-53 yddC - - - - - - -
MDCBHCFC_03211 9.82e-118 yddD - - S - - - TcpE family
MDCBHCFC_03212 0.0 yddE - - S - - - AAA-like domain
MDCBHCFC_03213 9.43e-73 - - - S - - - Domain of unknown function (DUF1874)
MDCBHCFC_03214 0.0 yddG - - S - - - maturation of SSU-rRNA
MDCBHCFC_03215 4.54e-241 yddH - - M - - - Lysozyme-like
MDCBHCFC_03216 1.46e-107 yddI - - - - - - -
MDCBHCFC_03217 9.82e-84 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
MDCBHCFC_03219 1.06e-176 - - - J - - - tRNA cytidylyltransferase activity
MDCBHCFC_03220 4.03e-88 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
MDCBHCFC_03222 6.18e-77 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
MDCBHCFC_03223 7.49e-25 - - - - - - - -
MDCBHCFC_03228 6.76e-143 ydeA - - S - - - DJ-1/PfpI family
MDCBHCFC_03229 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
MDCBHCFC_03230 1.65e-81 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
MDCBHCFC_03231 1.02e-172 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MDCBHCFC_03232 7.28e-208 - - - K - - - AraC-like ligand binding domain
MDCBHCFC_03233 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MDCBHCFC_03234 2.75e-211 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
MDCBHCFC_03235 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDCBHCFC_03236 5.39e-277 ydeG - - EGP - - - Major facilitator superfamily
MDCBHCFC_03237 7.89e-71 ydeH - - - - - - -
MDCBHCFC_03238 4.05e-135 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MDCBHCFC_03239 2.56e-142 - - - - - - - -
MDCBHCFC_03240 3.67e-194 ydeK - - EG - - - -transporter
MDCBHCFC_03241 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDCBHCFC_03242 4.3e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
MDCBHCFC_03243 3.99e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
MDCBHCFC_03244 1.44e-72 - - - K - - - HxlR-like helix-turn-helix
MDCBHCFC_03245 4.62e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MDCBHCFC_03246 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
MDCBHCFC_03247 3.53e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MDCBHCFC_03248 9.39e-186 - - - J - - - GNAT acetyltransferase
MDCBHCFC_03249 1.18e-191 - - - K - - - Transcriptional regulator
MDCBHCFC_03250 3.98e-155 nodB1 - - G - - - deacetylase
MDCBHCFC_03251 2.06e-198 - - - - - - - -
MDCBHCFC_03252 3.09e-278 - - - T - - - GHKL domain
MDCBHCFC_03253 9.3e-159 - - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MDCBHCFC_03254 4.85e-191 - - - EG - - - EamA-like transporter family
MDCBHCFC_03255 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MDCBHCFC_03256 3.32e-148 ydfE - - S - - - Flavin reductase like domain
MDCBHCFC_03257 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MDCBHCFC_03258 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MDCBHCFC_03259 2.77e-251 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_03260 1.33e-141 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MDCBHCFC_03261 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
MDCBHCFC_03262 1.31e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MDCBHCFC_03263 2.91e-187 - - - K - - - Bacterial transcription activator, effector binding domain
MDCBHCFC_03264 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDCBHCFC_03265 3.56e-138 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
MDCBHCFC_03266 2.24e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
MDCBHCFC_03267 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
MDCBHCFC_03268 3.63e-72 ydfQ - - CO - - - Thioredoxin
MDCBHCFC_03269 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
MDCBHCFC_03270 1.59e-40 - - - - - - - -
MDCBHCFC_03272 5.41e-126 ydfR - - S - - - Protein of unknown function (DUF421)
MDCBHCFC_03273 2.57e-159 ydfS - - S - - - Protein of unknown function (DUF421)
MDCBHCFC_03274 2.57e-89 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MDCBHCFC_03275 1.53e-47 ydgA - - S - - - Spore germination protein gerPA/gerPF
MDCBHCFC_03276 4.99e-44 ydgB - - S - - - Spore germination protein gerPA/gerPF
MDCBHCFC_03277 4.92e-127 ydgC - - K - - - Bacterial regulatory proteins, tetR family
MDCBHCFC_03278 5.76e-70 - - - S - - - DoxX-like family
MDCBHCFC_03279 3.15e-108 yycN - - K - - - Acetyltransferase
MDCBHCFC_03280 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
MDCBHCFC_03281 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MDCBHCFC_03282 2.83e-116 - - - S - - - DinB family
MDCBHCFC_03283 8.12e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDCBHCFC_03284 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
MDCBHCFC_03285 6.42e-147 ydgI - - C - - - nitroreductase
MDCBHCFC_03286 2.22e-88 - - - K - - - Winged helix DNA-binding domain
MDCBHCFC_03287 4.02e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
MDCBHCFC_03288 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
MDCBHCFC_03289 2.14e-157 ydhC - - K - - - FCD
MDCBHCFC_03290 5.16e-309 ydhD - - M - - - Glycosyl hydrolase
MDCBHCFC_03291 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MDCBHCFC_03292 3.52e-162 - - - - - - - -
MDCBHCFC_03293 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
MDCBHCFC_03294 2.26e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MDCBHCFC_03296 3.12e-107 - - - K - - - Acetyltransferase (GNAT) domain
MDCBHCFC_03297 1.28e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MDCBHCFC_03298 2.59e-126 ydhK - - M - - - Protein of unknown function (DUF1541)
MDCBHCFC_03299 5.17e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
MDCBHCFC_03300 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_03301 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_03302 3.76e-304 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCBHCFC_03303 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDCBHCFC_03304 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
MDCBHCFC_03305 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
MDCBHCFC_03306 5.09e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MDCBHCFC_03307 1.08e-267 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MDCBHCFC_03308 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
MDCBHCFC_03311 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDCBHCFC_03312 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDCBHCFC_03313 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
MDCBHCFC_03314 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDCBHCFC_03315 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MDCBHCFC_03316 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDCBHCFC_03317 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDCBHCFC_03318 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDCBHCFC_03319 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDCBHCFC_03320 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
MDCBHCFC_03321 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDCBHCFC_03322 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDCBHCFC_03323 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MDCBHCFC_03324 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MDCBHCFC_03325 1.13e-98 - - - S - - - Bacterial PH domain
MDCBHCFC_03326 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
MDCBHCFC_03327 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MDCBHCFC_03328 4.53e-145 yyaC - - S - - - Sporulation protein YyaC
MDCBHCFC_03329 5.34e-227 yyaD - - S - - - Membrane
MDCBHCFC_03330 7.41e-45 yyzM - - S - - - protein conserved in bacteria
MDCBHCFC_03331 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDCBHCFC_03332 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDCBHCFC_03333 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MDCBHCFC_03334 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDCBHCFC_03335 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDCBHCFC_03336 3.43e-186 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MDCBHCFC_03337 2.05e-228 ccpB - - K - - - Transcriptional regulator
MDCBHCFC_03338 1.99e-87 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDCBHCFC_03339 7.68e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
MDCBHCFC_03340 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
MDCBHCFC_03341 5.15e-216 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
MDCBHCFC_03342 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MDCBHCFC_03344 1.99e-77 - - - - - - - -
MDCBHCFC_03345 1.28e-55 - - - L - - - Recombinase
MDCBHCFC_03346 9.75e-90 - - - T - - - Nacht domain
MDCBHCFC_03347 1.37e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
MDCBHCFC_03348 1.82e-203 - - - EG - - - EamA-like transporter family
MDCBHCFC_03349 1.34e-88 - - - K - - - MerR HTH family regulatory protein
MDCBHCFC_03350 9.96e-30 - - - K - - - acetyltransferase
MDCBHCFC_03351 6.31e-139 yyaP - - H - - - RibD C-terminal domain
MDCBHCFC_03352 4.13e-83 - - - S - - - YjbR
MDCBHCFC_03353 2.33e-120 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
MDCBHCFC_03354 1.05e-125 yyaS - - S ko:K07149 - ko00000 Membrane
MDCBHCFC_03355 5.75e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
MDCBHCFC_03356 4.54e-100 yybA - - K - - - transcriptional
MDCBHCFC_03357 2.16e-164 - - - S - - - Metallo-beta-lactamase superfamily
MDCBHCFC_03358 3.02e-88 - - - S - - - SnoaL-like domain
MDCBHCFC_03359 2.13e-185 - - - - - - - -
MDCBHCFC_03360 5.1e-141 - - - K - - - TipAS antibiotic-recognition domain
MDCBHCFC_03361 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_03363 3.67e-80 - - - - - - - -
MDCBHCFC_03364 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MDCBHCFC_03365 6.68e-90 yybR - - K - - - Transcriptional regulator
MDCBHCFC_03366 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
MDCBHCFC_03368 7.43e-205 yybS - - S - - - membrane
MDCBHCFC_03369 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MDCBHCFC_03370 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MDCBHCFC_03371 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDCBHCFC_03372 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
MDCBHCFC_03373 1.89e-22 yycC - - K - - - YycC-like protein
MDCBHCFC_03375 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
MDCBHCFC_03376 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MDCBHCFC_03377 9.45e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDCBHCFC_03378 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDCBHCFC_03383 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_03384 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_03385 0.0 yycH - - S - - - protein conserved in bacteria
MDCBHCFC_03386 1.2e-200 yycI - - S - - - protein conserved in bacteria
MDCBHCFC_03387 4.68e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MDCBHCFC_03388 2.82e-280 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MDCBHCFC_03389 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MDCBHCFC_03390 1.29e-293 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
MDCBHCFC_03391 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MDCBHCFC_03392 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MDCBHCFC_03394 1.23e-238 - - - S - - - aspartate phosphatase
MDCBHCFC_03395 3.55e-109 yycN - - K - - - Acetyltransferase
MDCBHCFC_03396 4.81e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MDCBHCFC_03397 7.08e-272 yycP - - - - - - -
MDCBHCFC_03398 1.07e-39 yycQ - - S - - - Protein of unknown function (DUF2651)
MDCBHCFC_03400 3.01e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MDCBHCFC_03401 2.93e-83 - - - - - - - -
MDCBHCFC_03403 1.23e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDCBHCFC_03404 1.34e-88 - - - S - - - Domain of unknown function (DUF1837)
MDCBHCFC_03405 6.69e-214 - - - L - - - helicase
MDCBHCFC_03406 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
MDCBHCFC_03407 8.12e-17 - - - - - - - -
MDCBHCFC_03408 1.35e-237 - - - S - - - Radical SAM superfamily
MDCBHCFC_03409 3.65e-172 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
MDCBHCFC_03410 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDCBHCFC_03411 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MDCBHCFC_03412 3.04e-24 - - - - - - - -
MDCBHCFC_03413 3.94e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_03414 3.04e-24 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_03415 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDCBHCFC_03416 1.58e-237 - - - S - - - Polysaccharide pyruvyl transferase
MDCBHCFC_03417 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
MDCBHCFC_03418 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
MDCBHCFC_03419 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDCBHCFC_03420 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
MDCBHCFC_03421 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MDCBHCFC_03422 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
MDCBHCFC_03423 4.04e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MDCBHCFC_03424 3.62e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
MDCBHCFC_03425 1.27e-152 yxaC - - M - - - effector of murein hydrolase
MDCBHCFC_03426 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
MDCBHCFC_03427 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDCBHCFC_03428 1.5e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_03429 3.22e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
MDCBHCFC_03430 1.05e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
MDCBHCFC_03431 1.25e-284 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
MDCBHCFC_03432 4.03e-99 yxaI - - S - - - membrane protein domain
MDCBHCFC_03433 3.11e-80 - - - S - - - Family of unknown function (DUF5391)
MDCBHCFC_03434 7.49e-137 yxaL - - S - - - PQQ-like domain
MDCBHCFC_03435 3.35e-26 yxaI - - S - - - membrane protein domain
MDCBHCFC_03437 5.66e-312 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MDCBHCFC_03438 9.9e-264 yxbF - - K - - - Bacterial regulatory proteins, tetR family
MDCBHCFC_03439 1.81e-169 - - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
MDCBHCFC_03440 5.97e-293 - - - V ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 Peptidase C39 family
MDCBHCFC_03443 2.67e-188 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MDCBHCFC_03445 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
MDCBHCFC_03446 6.59e-310 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDCBHCFC_03447 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
MDCBHCFC_03449 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MDCBHCFC_03450 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
MDCBHCFC_03451 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDCBHCFC_03452 1.41e-199 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MDCBHCFC_03453 1.23e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MDCBHCFC_03454 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MDCBHCFC_03455 1.43e-221 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MDCBHCFC_03456 4.89e-297 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
MDCBHCFC_03457 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MDCBHCFC_03458 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
MDCBHCFC_03459 5.63e-194 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MDCBHCFC_03460 4.69e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MDCBHCFC_03461 1.62e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MDCBHCFC_03462 2.59e-229 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_03463 4.46e-180 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_03464 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
MDCBHCFC_03465 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
MDCBHCFC_03466 7.09e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDCBHCFC_03467 9.65e-91 - - - - - - - -
MDCBHCFC_03468 7.57e-28 yxeD - - - - - - -
MDCBHCFC_03469 7.32e-42 yxeE - - - - - - -
MDCBHCFC_03472 9.44e-193 yxeH - - S - - - hydrolases of the HAD superfamily
MDCBHCFC_03473 4.33e-234 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MDCBHCFC_03474 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDCBHCFC_03475 1.8e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDCBHCFC_03476 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
MDCBHCFC_03477 6.05e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
MDCBHCFC_03478 1.32e-168 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_03479 3.37e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
MDCBHCFC_03480 1.33e-310 yxeQ - - S - - - MmgE/PrpD family
MDCBHCFC_03481 2.21e-255 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
MDCBHCFC_03482 4.33e-196 - - - S - - - Domain of Unknown Function (DUF1206)
MDCBHCFC_03483 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MDCBHCFC_03484 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDCBHCFC_03485 2.72e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDCBHCFC_03486 9.46e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
MDCBHCFC_03487 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MDCBHCFC_03488 2.21e-227 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MDCBHCFC_03489 2.61e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
MDCBHCFC_03490 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MDCBHCFC_03491 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MDCBHCFC_03492 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MDCBHCFC_03493 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
MDCBHCFC_03494 3.79e-37 - - - S - - - Domain of unknown function (DUF5082)
MDCBHCFC_03495 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
MDCBHCFC_03496 2.14e-156 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
MDCBHCFC_03498 2.81e-26 - - - S - - - protein conserved in bacteria
MDCBHCFC_03500 7.06e-168 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
MDCBHCFC_03501 8.25e-69 - - - - - - - -
MDCBHCFC_03502 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_03503 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDCBHCFC_03504 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
MDCBHCFC_03505 7.23e-211 yxxF - - EG - - - EamA-like transporter family
MDCBHCFC_03506 0.0 wapA - - M - - - COG3209 Rhs family protein
MDCBHCFC_03508 3.42e-173 - - - - - - - -
MDCBHCFC_03509 2.66e-107 yxiI - - S - - - Protein of unknown function (DUF2716)
MDCBHCFC_03510 4.75e-57 yxiJ - - S - - - YxiJ-like protein
MDCBHCFC_03513 2.65e-269 - - - E - - - GDSL-like Lipase/Acylhydrolase
MDCBHCFC_03514 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MDCBHCFC_03515 1.27e-290 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
MDCBHCFC_03516 1.25e-141 - - - - - - - -
MDCBHCFC_03517 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MDCBHCFC_03518 2.07e-182 bglS - - M - - - licheninase activity
MDCBHCFC_03519 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MDCBHCFC_03520 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MDCBHCFC_03521 7.65e-62 yxiS - - - - - - -
MDCBHCFC_03522 1.03e-133 - - - T - - - Domain of unknown function (DUF4163)
MDCBHCFC_03523 1.72e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MDCBHCFC_03525 8.1e-200 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
MDCBHCFC_03526 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
MDCBHCFC_03527 1.89e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MDCBHCFC_03528 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MDCBHCFC_03529 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MDCBHCFC_03530 1.09e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MDCBHCFC_03531 9.67e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
MDCBHCFC_03532 5.82e-111 yxjI - - S - - - LURP-one-related
MDCBHCFC_03534 3.16e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MDCBHCFC_03535 3.01e-145 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
MDCBHCFC_03536 1.15e-241 - - - T - - - Signal transduction histidine kinase
MDCBHCFC_03537 6.58e-101 - - - S - - - Protein of unknown function (DUF1453)
MDCBHCFC_03538 1.74e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MDCBHCFC_03539 4.99e-100 yxkC - - S - - - Domain of unknown function (DUF4352)
MDCBHCFC_03540 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDCBHCFC_03541 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDCBHCFC_03542 5.53e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MDCBHCFC_03543 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDCBHCFC_03544 1.3e-199 yxkH - - G - - - Polysaccharide deacetylase
MDCBHCFC_03546 0.0 - - - O - - - Peptidase family M48
MDCBHCFC_03547 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
MDCBHCFC_03548 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
MDCBHCFC_03549 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
MDCBHCFC_03550 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
MDCBHCFC_03551 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
MDCBHCFC_03552 6.19e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDCBHCFC_03553 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
MDCBHCFC_03554 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_03555 1.3e-60 yxlC - - S - - - Family of unknown function (DUF5345)
MDCBHCFC_03556 1.63e-39 - - - - - - - -
MDCBHCFC_03557 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
MDCBHCFC_03558 3.47e-212 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_03559 1.61e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MDCBHCFC_03560 2.37e-272 yxlH - - EGP - - - Major Facilitator Superfamily
MDCBHCFC_03561 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
MDCBHCFC_03562 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MDCBHCFC_03563 8.94e-28 yxzF - - - - - - -
MDCBHCFC_03564 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MDCBHCFC_03565 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
MDCBHCFC_03566 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCBHCFC_03567 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_03568 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MDCBHCFC_03569 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MDCBHCFC_03570 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MDCBHCFC_03571 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDCBHCFC_03572 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCBHCFC_03573 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
MDCBHCFC_03574 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDCBHCFC_03575 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MDCBHCFC_03576 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
MDCBHCFC_03577 2.14e-162 - - - EGP - - - Permeases of the major facilitator superfamily
MDCBHCFC_03578 7.93e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MDCBHCFC_03579 6.59e-117 - - - K - - - Helix-turn-helix XRE-family like proteins
MDCBHCFC_03580 1.83e-316 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
MDCBHCFC_03581 2.59e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDCBHCFC_03582 1.46e-113 ywaE - - K - - - Transcriptional regulator
MDCBHCFC_03583 1.17e-156 ywaF - - S - - - Integral membrane protein
MDCBHCFC_03584 1.87e-216 gspA - - M - - - General stress
MDCBHCFC_03585 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MDCBHCFC_03586 5.89e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_03587 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MDCBHCFC_03588 2.33e-305 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDCBHCFC_03589 3.41e-159 ywbB - - S - - - Protein of unknown function (DUF2711)
MDCBHCFC_03590 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
MDCBHCFC_03591 1.34e-278 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
MDCBHCFC_03592 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
MDCBHCFC_03593 7.46e-278 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
MDCBHCFC_03594 1.21e-143 ywbG - - M - - - effector of murein hydrolase
MDCBHCFC_03595 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MDCBHCFC_03596 2.7e-203 ywbI - - K - - - Transcriptional regulator
MDCBHCFC_03597 2.19e-183 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MDCBHCFC_03598 1.49e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MDCBHCFC_03599 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
MDCBHCFC_03600 4.87e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
MDCBHCFC_03601 7.29e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
MDCBHCFC_03602 3.25e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
MDCBHCFC_03603 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDCBHCFC_03604 2.13e-64 ywcB - - S - - - Protein of unknown function, DUF485
MDCBHCFC_03606 3.42e-158 ywcC - - K - - - transcriptional regulator
MDCBHCFC_03607 3.33e-77 gtcA - - S - - - GtrA-like protein
MDCBHCFC_03608 7.27e-287 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDCBHCFC_03609 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MDCBHCFC_03610 5.11e-49 ydaS - - S - - - membrane
MDCBHCFC_03611 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MDCBHCFC_03612 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MDCBHCFC_03613 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MDCBHCFC_03614 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
MDCBHCFC_03615 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
MDCBHCFC_03616 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MDCBHCFC_03617 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
MDCBHCFC_03618 1.4e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MDCBHCFC_03619 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MDCBHCFC_03621 5.24e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
MDCBHCFC_03622 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
MDCBHCFC_03623 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_03624 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MDCBHCFC_03625 6.19e-39 ywdA - - - - - - -
MDCBHCFC_03626 1.28e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MDCBHCFC_03627 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MDCBHCFC_03628 8.74e-146 ywdD - - - - - - -
MDCBHCFC_03630 1.29e-189 ywdF - - S - - - Glycosyltransferase like family 2
MDCBHCFC_03631 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDCBHCFC_03632 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MDCBHCFC_03633 2.65e-64 ywdI - - S - - - Family of unknown function (DUF5327)
MDCBHCFC_03634 7.57e-303 ywdJ - - F - - - Xanthine uracil
MDCBHCFC_03635 1.59e-78 ywdK - - S - - - small membrane protein
MDCBHCFC_03636 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MDCBHCFC_03637 4.68e-186 spsA - - M - - - Spore Coat
MDCBHCFC_03638 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
MDCBHCFC_03639 6.44e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
MDCBHCFC_03640 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
MDCBHCFC_03641 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
MDCBHCFC_03642 1.49e-165 spsF - - M ko:K07257 - ko00000 Spore Coat
MDCBHCFC_03643 5.98e-242 spsG - - M - - - Spore Coat
MDCBHCFC_03644 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDCBHCFC_03645 3.7e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDCBHCFC_03646 8.77e-202 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDCBHCFC_03647 1.52e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
MDCBHCFC_03648 6.13e-100 - - - - - - - -
MDCBHCFC_03649 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MDCBHCFC_03650 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
MDCBHCFC_03651 0.0 rocB - - E - - - arginine degradation protein
MDCBHCFC_03652 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MDCBHCFC_03653 8.95e-274 ywfA - - EGP - - - -transporter
MDCBHCFC_03654 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MDCBHCFC_03655 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MDCBHCFC_03656 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_03657 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MDCBHCFC_03658 1.85e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MDCBHCFC_03659 1.23e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MDCBHCFC_03660 2.37e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
MDCBHCFC_03661 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
MDCBHCFC_03662 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
MDCBHCFC_03663 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_03664 1.77e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MDCBHCFC_03665 7.47e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
MDCBHCFC_03666 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
MDCBHCFC_03667 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
MDCBHCFC_03668 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
MDCBHCFC_03669 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
MDCBHCFC_03670 7.42e-102 yffB - - K - - - Transcriptional regulator
MDCBHCFC_03671 1.34e-300 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
MDCBHCFC_03675 2.59e-229 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MDCBHCFC_03676 2.13e-111 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
MDCBHCFC_03677 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
MDCBHCFC_03678 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MDCBHCFC_03679 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDCBHCFC_03680 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
MDCBHCFC_03681 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MDCBHCFC_03682 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDCBHCFC_03683 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MDCBHCFC_03684 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MDCBHCFC_03685 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
MDCBHCFC_03686 1.74e-166 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MDCBHCFC_03687 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDCBHCFC_03688 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDCBHCFC_03690 1.93e-53 - - - - - - - -
MDCBHCFC_03691 7.05e-293 - - - S - - - Bacterial EndoU nuclease
MDCBHCFC_03694 4.31e-82 yozB - - S ko:K08976 - ko00000 Membrane
MDCBHCFC_03695 1.19e-30 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MDCBHCFC_03696 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
MDCBHCFC_03697 4.32e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MDCBHCFC_03698 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
MDCBHCFC_03699 6.03e-221 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MDCBHCFC_03700 3.1e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
MDCBHCFC_03701 4.25e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDCBHCFC_03702 4.44e-174 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
MDCBHCFC_03703 1.04e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
MDCBHCFC_03704 4.59e-247 - - - S - - - Ion transport 2 domain protein
MDCBHCFC_03705 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDCBHCFC_03706 2.88e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
MDCBHCFC_03707 1.79e-84 ydjM - - M - - - Lytic transglycolase
MDCBHCFC_03708 1.14e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
MDCBHCFC_03710 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
MDCBHCFC_03711 2.95e-201 - - - I - - - Alpha/beta hydrolase family
MDCBHCFC_03712 1.18e-227 yeaA - - S - - - Protein of unknown function (DUF4003)
MDCBHCFC_03713 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
MDCBHCFC_03714 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
MDCBHCFC_03715 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDCBHCFC_03716 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
MDCBHCFC_03717 5.31e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MDCBHCFC_03718 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
MDCBHCFC_03719 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MDCBHCFC_03720 1.05e-109 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_03721 0.0 - - - S - - - Domain of unknown function (DUF4179)
MDCBHCFC_03722 2.41e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MDCBHCFC_03723 8.31e-165 yebC - - M - - - Membrane
MDCBHCFC_03725 1.08e-119 yebE - - S - - - UPF0316 protein
MDCBHCFC_03726 3.13e-38 yebG - - S - - - NETI protein
MDCBHCFC_03727 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDCBHCFC_03728 2.91e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDCBHCFC_03729 2.81e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDCBHCFC_03730 1.18e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MDCBHCFC_03731 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDCBHCFC_03732 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDCBHCFC_03733 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDCBHCFC_03734 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDCBHCFC_03735 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MDCBHCFC_03736 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MDCBHCFC_03737 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MDCBHCFC_03738 3.68e-294 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MDCBHCFC_03739 1.06e-95 - - - K - - - helix_turn_helix ASNC type
MDCBHCFC_03740 5.01e-293 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
MDCBHCFC_03741 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
MDCBHCFC_03742 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
MDCBHCFC_03743 2.35e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
MDCBHCFC_03744 7.62e-68 yerC - - S - - - protein conserved in bacteria
MDCBHCFC_03745 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
MDCBHCFC_03747 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MDCBHCFC_03748 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MDCBHCFC_03749 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDCBHCFC_03750 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
MDCBHCFC_03751 2.45e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
MDCBHCFC_03752 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
MDCBHCFC_03753 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDCBHCFC_03754 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDCBHCFC_03755 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDCBHCFC_03756 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDCBHCFC_03757 2.23e-185 yerO - - K - - - Transcriptional regulator
MDCBHCFC_03758 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MDCBHCFC_03759 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MDCBHCFC_03760 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDCBHCFC_03761 2.72e-06 - - - - - - - -
MDCBHCFC_03762 2.53e-47 - - - S - - - Protein of unknown function, DUF600
MDCBHCFC_03763 1.72e-71 - - - S - - - Protein of unknown function, DUF600
MDCBHCFC_03764 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
MDCBHCFC_03765 1.18e-232 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
MDCBHCFC_03767 9.61e-269 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
MDCBHCFC_03769 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
MDCBHCFC_03771 9.93e-130 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
MDCBHCFC_03772 1.6e-103 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
MDCBHCFC_03773 4.79e-193 yesF - - GM - - - NAD(P)H-binding
MDCBHCFC_03774 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
MDCBHCFC_03775 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
MDCBHCFC_03776 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
MDCBHCFC_03777 3.99e-129 yesJ - - K - - - Acetyltransferase (GNAT) family
MDCBHCFC_03779 1.38e-132 yesL - - S - - - Protein of unknown function, DUF624
MDCBHCFC_03780 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDCBHCFC_03781 7.38e-253 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
MDCBHCFC_03782 1.38e-312 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDCBHCFC_03783 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDCBHCFC_03784 5.97e-209 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDCBHCFC_03785 2.79e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
MDCBHCFC_03786 0.0 yesS - - K - - - Transcriptional regulator
MDCBHCFC_03787 1.75e-162 - - - E - - - GDSL-like Lipase/Acylhydrolase
MDCBHCFC_03788 3.88e-167 yesU - - S - - - Domain of unknown function (DUF1961)
MDCBHCFC_03789 4.02e-145 - - - S - - - Protein of unknown function, DUF624
MDCBHCFC_03790 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
MDCBHCFC_03791 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
MDCBHCFC_03792 4.34e-158 - - - E - - - GDSL-like Lipase/Acylhydrolase
MDCBHCFC_03793 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
MDCBHCFC_03794 0.0 yetA - - - - - - -
MDCBHCFC_03795 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDCBHCFC_03796 9.71e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
MDCBHCFC_03797 1.58e-208 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDCBHCFC_03798 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
MDCBHCFC_03799 1.81e-157 yetF - - S - - - membrane
MDCBHCFC_03800 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
MDCBHCFC_03801 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDCBHCFC_03802 1.75e-44 - - - - - - - -
MDCBHCFC_03803 4.37e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MDCBHCFC_03804 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
MDCBHCFC_03805 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
MDCBHCFC_03806 2.04e-08 - - - EG - - - EamA-like transporter family
MDCBHCFC_03807 1.86e-114 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MDCBHCFC_03808 1.78e-265 yetM - - CH - - - FAD binding domain
MDCBHCFC_03810 1.88e-249 yetN - - S - - - Protein of unknown function (DUF3900)
MDCBHCFC_03811 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
MDCBHCFC_03812 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MDCBHCFC_03813 4.01e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
MDCBHCFC_03814 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
MDCBHCFC_03815 9.02e-228 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
MDCBHCFC_03816 2.84e-285 yfnE - - S - - - Glycosyltransferase like family 2
MDCBHCFC_03817 3.88e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
MDCBHCFC_03818 5.1e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_03819 2.05e-165 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MDCBHCFC_03820 6.88e-312 yfnA - - E ko:K03294 - ko00000 amino acid
MDCBHCFC_03821 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MDCBHCFC_03822 5.14e-161 yfmS - - NT - - - chemotaxis protein
MDCBHCFC_03823 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDCBHCFC_03824 1.47e-95 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
MDCBHCFC_03825 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
MDCBHCFC_03826 2.42e-263 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
MDCBHCFC_03827 4.96e-64 - - - O - - - Subtilase family
MDCBHCFC_03828 9.1e-23 - - - - - - - -
MDCBHCFC_03830 3.95e-74 - - - - - - - -
MDCBHCFC_03831 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MDCBHCFC_03832 7.25e-264 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
MDCBHCFC_03833 3.75e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
MDCBHCFC_03834 6.69e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
MDCBHCFC_03835 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MDCBHCFC_03836 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_03837 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_03838 5.57e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MDCBHCFC_03839 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
MDCBHCFC_03840 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
MDCBHCFC_03841 2.01e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
MDCBHCFC_03842 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MDCBHCFC_03843 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
MDCBHCFC_03844 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MDCBHCFC_03845 5.66e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
MDCBHCFC_03846 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
MDCBHCFC_03847 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
MDCBHCFC_03848 5.59e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MDCBHCFC_03849 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MDCBHCFC_03850 1.98e-156 yflK - - S - - - protein conserved in bacteria
MDCBHCFC_03851 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
MDCBHCFC_03852 6.9e-27 yflI - - - - - - -
MDCBHCFC_03853 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
MDCBHCFC_03854 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MDCBHCFC_03855 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MDCBHCFC_03856 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
MDCBHCFC_03857 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
MDCBHCFC_03858 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
MDCBHCFC_03859 2.45e-246 yfkT - - E ko:K06309 - ko00000 Spore germination protein
MDCBHCFC_03861 2.66e-270 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
MDCBHCFC_03862 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
MDCBHCFC_03863 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_03864 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
MDCBHCFC_03865 1.02e-171 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
MDCBHCFC_03866 8.75e-160 frp - - C - - - nitroreductase
MDCBHCFC_03867 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MDCBHCFC_03868 1.11e-113 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
MDCBHCFC_03869 1.46e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_03870 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
MDCBHCFC_03871 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDCBHCFC_03872 1.03e-66 yfkI - - S - - - gas vesicle protein
MDCBHCFC_03873 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MDCBHCFC_03874 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
MDCBHCFC_03875 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
MDCBHCFC_03876 3.69e-189 yfkD - - S - - - YfkD-like protein
MDCBHCFC_03877 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
MDCBHCFC_03878 1.02e-282 yfkA - - S - - - YfkB-like domain
MDCBHCFC_03879 3.26e-36 yfjT - - - - - - -
MDCBHCFC_03880 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
MDCBHCFC_03881 1.8e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MDCBHCFC_03882 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
MDCBHCFC_03883 4.58e-213 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MDCBHCFC_03884 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDCBHCFC_03885 3.04e-59 - - - S - - - YfzA-like protein
MDCBHCFC_03886 4.72e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDCBHCFC_03887 2.25e-109 yfjM - - S - - - Psort location Cytoplasmic, score
MDCBHCFC_03888 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MDCBHCFC_03889 1.59e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MDCBHCFC_03890 4.89e-264 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDCBHCFC_03891 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MDCBHCFC_03892 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
MDCBHCFC_03893 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
MDCBHCFC_03894 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
MDCBHCFC_03895 6.46e-102 - - - S - - - Family of unknown function (DUF5381)
MDCBHCFC_03896 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
MDCBHCFC_03897 2.5e-185 yfjC - - - - - - -
MDCBHCFC_03898 1.12e-269 yfjB - - - - - - -
MDCBHCFC_03899 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
MDCBHCFC_03900 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MDCBHCFC_03901 5.03e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MDCBHCFC_03902 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDCBHCFC_03903 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
MDCBHCFC_03904 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MDCBHCFC_03905 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
MDCBHCFC_03906 1.65e-83 yfiD3 - - S - - - DoxX
MDCBHCFC_03907 3.32e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MDCBHCFC_03908 4.15e-240 baeS - - T - - - Histidine kinase
MDCBHCFC_03909 8.27e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
MDCBHCFC_03910 5.33e-215 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MDCBHCFC_03911 1.2e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MDCBHCFC_03912 8.45e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
MDCBHCFC_03913 1.89e-128 padR - - K - - - transcriptional
MDCBHCFC_03914 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
MDCBHCFC_03915 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MDCBHCFC_03916 3.3e-138 yfiR - - K - - - Transcriptional regulator
MDCBHCFC_03917 2.09e-270 yfiS - - EGP - - - Major facilitator superfamily
MDCBHCFC_03918 1.15e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
MDCBHCFC_03919 0.0 yfiU - - EGP - - - the major facilitator superfamily
MDCBHCFC_03920 2.11e-103 yfiV - - K - - - transcriptional
MDCBHCFC_03921 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDCBHCFC_03922 3.83e-231 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDCBHCFC_03923 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_03924 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDCBHCFC_03925 2.44e-211 yfhB - - S - - - PhzF family
MDCBHCFC_03926 6.76e-137 yfhC - - C - - - nitroreductase
MDCBHCFC_03927 8.86e-35 yfhD - - S - - - YfhD-like protein
MDCBHCFC_03929 1.09e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
MDCBHCFC_03930 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MDCBHCFC_03931 2.66e-68 yfhH - - S - - - Protein of unknown function (DUF1811)
MDCBHCFC_03933 2.45e-268 yfhI - - EGP - - - -transporter
MDCBHCFC_03934 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
MDCBHCFC_03935 8.95e-60 yfhJ - - S - - - WVELL protein
MDCBHCFC_03936 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
MDCBHCFC_03937 1.66e-62 yfhL - - S - - - SdpI/YhfL protein family
MDCBHCFC_03938 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
MDCBHCFC_03939 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
MDCBHCFC_03940 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MDCBHCFC_03941 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
MDCBHCFC_03942 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
MDCBHCFC_03943 1.73e-48 yfhS - - - - - - -
MDCBHCFC_03944 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MDCBHCFC_03945 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
MDCBHCFC_03946 8.19e-49 ygaB - - S - - - YgaB-like protein
MDCBHCFC_03947 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MDCBHCFC_03948 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MDCBHCFC_03949 1.87e-238 ygaE - - S - - - Membrane
MDCBHCFC_03950 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
MDCBHCFC_03951 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
MDCBHCFC_03952 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MDCBHCFC_03953 3.38e-73 ygzB - - S - - - UPF0295 protein
MDCBHCFC_03954 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
MDCBHCFC_03955 2.72e-50 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
MDCBHCFC_03956 6.65e-78 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MDCBHCFC_03960 5.59e-22 - - - - - - - -
MDCBHCFC_03963 6.23e-150 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
MDCBHCFC_03967 8.62e-48 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
MDCBHCFC_03968 2.25e-284 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase III
MDCBHCFC_03969 9.47e-120 - - - L - - - Protein of unknown function (DUF3991)
MDCBHCFC_03970 1.24e-24 - - - - - - - -
MDCBHCFC_03971 4.63e-139 - - - - - - - -
MDCBHCFC_03972 9.74e-275 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 COG3505 Type IV secretory pathway, VirD4 components
MDCBHCFC_03974 5.38e-36 - - - - - - - -
MDCBHCFC_03975 4.51e-162 - - - M - - - Lysozyme-like
MDCBHCFC_03976 1.81e-135 - - - S - - - WXG100 protein secretion system (Wss), protein YukC
MDCBHCFC_03977 2.05e-302 traE - - U - - - Psort location Cytoplasmic, score
MDCBHCFC_03978 6.35e-83 - - - - - - - -
MDCBHCFC_03979 9.43e-46 - - - - - - - -
MDCBHCFC_03986 1.5e-110 - - - - - - - -
MDCBHCFC_03987 5.63e-117 - - - - - - - -
MDCBHCFC_03988 1.11e-156 - - - NU ko:K02283 - ko00000,ko02035,ko02044 Type II/IV secretion system protein
MDCBHCFC_03994 2.46e-232 - - - M - - - domain protein
MDCBHCFC_03996 4.02e-32 - - - S - - - Family of unknown function
MDCBHCFC_03997 5.14e-48 - - - K - - - Transcriptional
MDCBHCFC_03998 2.04e-53 - - - T - - - cheY-homologous receiver domain
MDCBHCFC_03999 1.01e-85 - - - T - - - Histidine kinase-like ATPases
MDCBHCFC_04000 3.11e-192 ydjC - - S - - - Abhydrolase domain containing 18
MDCBHCFC_04001 1.78e-205 - - - - - - - -
MDCBHCFC_04002 1.27e-134 - - - - ko:K18640 - ko00000,ko04812 -
MDCBHCFC_04005 1.67e-74 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MDCBHCFC_04006 2e-18 - - - - - - - -
MDCBHCFC_04007 3.29e-12 - - - - - - - -
MDCBHCFC_04008 3.48e-246 - - - S - - - MobA/MobL family
MDCBHCFC_04009 4.11e-169 - - - L - - - Psort location Cytoplasmic, score
MDCBHCFC_04014 1.82e-95 - - - S - - - Protein of unknown function DUF262
MDCBHCFC_04018 4.54e-57 - - - S - - - Conserved Protein
MDCBHCFC_04019 9.13e-42 - - - - - - - -
MDCBHCFC_04025 1.69e-88 - - - L - - - integrase family
MDCBHCFC_04030 1.68e-67 - - - S - - - YolD-like protein
MDCBHCFC_04031 1.69e-296 - - - S - - - damaged DNA binding
MDCBHCFC_04038 1.72e-57 - - - S - - - Protein of unknown function (DUF2786)
MDCBHCFC_04043 1.05e-121 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
MDCBHCFC_04051 0.0 - - - KL - - - N-6 DNA Methylase
MDCBHCFC_04052 2.99e-52 - - - K - - - Anti-sigma-K factor rskA
MDCBHCFC_04053 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MDCBHCFC_04054 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
MDCBHCFC_04055 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MDCBHCFC_04056 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
MDCBHCFC_04057 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDCBHCFC_04058 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MDCBHCFC_04059 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
MDCBHCFC_04060 3.02e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MDCBHCFC_04061 1.05e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MDCBHCFC_04062 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDCBHCFC_04063 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
MDCBHCFC_04064 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MDCBHCFC_04065 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDCBHCFC_04066 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDCBHCFC_04067 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
MDCBHCFC_04068 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MDCBHCFC_04069 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDCBHCFC_04070 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MDCBHCFC_04071 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDCBHCFC_04072 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDCBHCFC_04073 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDCBHCFC_04074 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDCBHCFC_04075 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MDCBHCFC_04076 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDCBHCFC_04077 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDCBHCFC_04078 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
MDCBHCFC_04079 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDCBHCFC_04080 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDCBHCFC_04081 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDCBHCFC_04082 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDCBHCFC_04083 4.3e-229 ybaC - - S - - - Alpha/beta hydrolase family
MDCBHCFC_04084 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MDCBHCFC_04085 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDCBHCFC_04086 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MDCBHCFC_04087 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDCBHCFC_04088 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDCBHCFC_04089 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDCBHCFC_04090 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDCBHCFC_04091 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDCBHCFC_04092 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDCBHCFC_04093 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MDCBHCFC_04094 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDCBHCFC_04095 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDCBHCFC_04096 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDCBHCFC_04097 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDCBHCFC_04098 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDCBHCFC_04099 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDCBHCFC_04100 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDCBHCFC_04101 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDCBHCFC_04102 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDCBHCFC_04103 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MDCBHCFC_04104 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MDCBHCFC_04105 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDCBHCFC_04106 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDCBHCFC_04107 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
MDCBHCFC_04108 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDCBHCFC_04109 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MDCBHCFC_04110 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDCBHCFC_04111 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDCBHCFC_04112 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDCBHCFC_04113 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MDCBHCFC_04114 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDCBHCFC_04115 1.28e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDCBHCFC_04116 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDCBHCFC_04117 6.15e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDCBHCFC_04118 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDCBHCFC_04119 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MDCBHCFC_04120 1.69e-183 ybaJ - - Q - - - Methyltransferase domain
MDCBHCFC_04121 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
MDCBHCFC_04122 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
MDCBHCFC_04123 1.05e-253 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MDCBHCFC_04124 2.1e-122 gerD - - - ko:K06294 - ko00000 -
MDCBHCFC_04125 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
MDCBHCFC_04126 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
MDCBHCFC_04127 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MDCBHCFC_04128 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDCBHCFC_04129 1.81e-41 yazB - - K - - - transcriptional
MDCBHCFC_04130 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MDCBHCFC_04131 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MDCBHCFC_04132 3.88e-204 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MDCBHCFC_04133 5.36e-215 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
MDCBHCFC_04134 4.92e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
MDCBHCFC_04135 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MDCBHCFC_04136 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MDCBHCFC_04137 2.72e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
MDCBHCFC_04138 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDCBHCFC_04139 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MDCBHCFC_04140 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDCBHCFC_04141 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
MDCBHCFC_04142 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDCBHCFC_04143 1.2e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
MDCBHCFC_04144 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
MDCBHCFC_04145 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
MDCBHCFC_04148 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
MDCBHCFC_04149 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MDCBHCFC_04150 1.49e-137 yabQ - - S - - - spore cortex biosynthesis protein
MDCBHCFC_04151 1.91e-66 yabP - - S - - - Sporulation protein YabP
MDCBHCFC_04152 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MDCBHCFC_04153 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MDCBHCFC_04154 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MDCBHCFC_04155 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
MDCBHCFC_04156 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDCBHCFC_04157 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
MDCBHCFC_04158 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDCBHCFC_04159 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MDCBHCFC_04160 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDCBHCFC_04161 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDCBHCFC_04162 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MDCBHCFC_04163 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
MDCBHCFC_04164 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MDCBHCFC_04165 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDCBHCFC_04166 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
MDCBHCFC_04167 5.32e-53 veg - - S - - - protein conserved in bacteria
MDCBHCFC_04168 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
MDCBHCFC_04169 2.05e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDCBHCFC_04170 2.03e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDCBHCFC_04171 4.1e-278 yabE - - T - - - protein conserved in bacteria
MDCBHCFC_04172 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
MDCBHCFC_04173 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDCBHCFC_04174 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
MDCBHCFC_04175 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDCBHCFC_04176 1.2e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
MDCBHCFC_04177 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
MDCBHCFC_04178 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
MDCBHCFC_04179 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
MDCBHCFC_04180 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MDCBHCFC_04181 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
MDCBHCFC_04182 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
MDCBHCFC_04183 5.69e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDCBHCFC_04184 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
MDCBHCFC_04185 1.02e-259 yaaN - - P - - - Belongs to the TelA family
MDCBHCFC_04186 3.83e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MDCBHCFC_04187 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
MDCBHCFC_04191 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
MDCBHCFC_04192 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
MDCBHCFC_04193 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDCBHCFC_04194 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDCBHCFC_04195 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDCBHCFC_04196 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDCBHCFC_04197 1.89e-123 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
MDCBHCFC_04198 2.99e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
MDCBHCFC_04199 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
MDCBHCFC_04200 2.15e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
MDCBHCFC_04202 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDCBHCFC_04203 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MDCBHCFC_04204 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MDCBHCFC_04205 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MDCBHCFC_04206 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MDCBHCFC_04207 3.04e-232 yaaC - - S - - - YaaC-like Protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)