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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HHOLCGFJ_00001	7.35e-250	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_00002	2.96e-105	-	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
HHOLCGFJ_00003	2.28e-248	oppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_00004	5.46e-192	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_00005	4.99e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_00006	8.72e-203	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
HHOLCGFJ_00007	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HHOLCGFJ_00008	1.26e-139	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HHOLCGFJ_00009	1.15e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HHOLCGFJ_00010	6.87e-257	degS	2.7.13.3	-	T	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HHOLCGFJ_00011	4.63e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHOLCGFJ_00012	3.16e-196	degV	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00013	1.15e-241	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HHOLCGFJ_00014	8.38e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HHOLCGFJ_00015	5.44e-99	yvyF	-	-	S	-	-	-	flagellar protein
HHOLCGFJ_00016	6.14e-53	-	-	-	N	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Anti-sigma-28 factor, FlgM
HHOLCGFJ_00017	1.12e-07	yvyG	-	-	NOU	-	-	-	Flagellar biosynthesis protein FlgN
HHOLCGFJ_00018	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HHOLCGFJ_00019	4.08e-247	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HHOLCGFJ_00020	2.99e-103	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HHOLCGFJ_00021	1.67e-46	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HHOLCGFJ_00022	3.19e-66	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
HHOLCGFJ_00023	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHOLCGFJ_00024	4.42e-87	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HHOLCGFJ_00026	7.77e-198	-	-	-	-	-	-	-	-
HHOLCGFJ_00027	6.79e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	cold-shock protein
HHOLCGFJ_00028	3.01e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHOLCGFJ_00029	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHOLCGFJ_00030	1.24e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHOLCGFJ_00031	8.63e-194	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HHOLCGFJ_00032	7.42e-161	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HHOLCGFJ_00033	7.66e-195	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HHOLCGFJ_00034	7.12e-176	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	peptidase
HHOLCGFJ_00035	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HHOLCGFJ_00036	2.62e-264	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHOLCGFJ_00037	1.66e-219	yoaV3	-	-	EG	-	-	-	EamA-like transporter family
HHOLCGFJ_00038	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHOLCGFJ_00039	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHOLCGFJ_00040	2.85e-204	yvlB	-	-	S	-	-	-	Putative adhesin
HHOLCGFJ_00042	3.6e-64	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HHOLCGFJ_00043	3.78e-219	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHOLCGFJ_00044	2.24e-199	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHOLCGFJ_00045	1.44e-206	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
HHOLCGFJ_00046	3.44e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HHOLCGFJ_00047	2.68e-110	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HHOLCGFJ_00048	1.15e-280	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HHOLCGFJ_00049	3.55e-146	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HHOLCGFJ_00050	7.19e-298	hisD	1.1.1.23, 1.1.1.308	-	E	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHOLCGFJ_00051	4.58e-140	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HHOLCGFJ_00052	1.71e-150	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHOLCGFJ_00053	8.99e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HHOLCGFJ_00054	6.86e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HHOLCGFJ_00055	5.1e-147	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HHOLCGFJ_00056	1.07e-188	-	-	-	K	-	-	-	FR47-like protein
HHOLCGFJ_00057	8.95e-313	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HHOLCGFJ_00058	2.39e-253	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HHOLCGFJ_00059	2.04e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHOLCGFJ_00060	1.28e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Nudix hydrolase
HHOLCGFJ_00061	4.57e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HHOLCGFJ_00062	1.09e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HHOLCGFJ_00063	5.08e-227	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HHOLCGFJ_00064	4.07e-52	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HHOLCGFJ_00065	2.76e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HHOLCGFJ_00066	1.8e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HHOLCGFJ_00067	5.2e-139	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HHOLCGFJ_00068	2.59e-276	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HHOLCGFJ_00069	7.15e-75	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
HHOLCGFJ_00070	2.39e-294	-	-	-	E	-	-	-	Peptidase dimerisation domain
HHOLCGFJ_00071	4.06e-134	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHOLCGFJ_00072	2.87e-305	sigL	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HHOLCGFJ_00073	1.55e-55	XAC3035	-	-	O	ko:K06191	-	ko00000	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HHOLCGFJ_00075	6.69e-263	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HHOLCGFJ_00076	1.05e-230	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HHOLCGFJ_00077	1.46e-240	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHOLCGFJ_00078	2.4e-278	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HHOLCGFJ_00079	5.86e-170	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHOLCGFJ_00080	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HHOLCGFJ_00081	9.59e-305	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHOLCGFJ_00082	3.78e-156	-	-	-	K	-	-	-	FCD
HHOLCGFJ_00083	1.49e-223	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HHOLCGFJ_00084	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHOLCGFJ_00085	8.5e-286	-	4.2.1.158	-	M	ko:K20022	-	ko00000,ko01000	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
HHOLCGFJ_00086	2.87e-221	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HHOLCGFJ_00087	2.39e-103	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
HHOLCGFJ_00088	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
HHOLCGFJ_00089	9.92e-104	yclD	-	-	-	-	-	-	-
HHOLCGFJ_00090	9.6e-38	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HHOLCGFJ_00091	1.64e-236	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHOLCGFJ_00092	4.6e-177	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	COG1647 Esterase lipase
HHOLCGFJ_00093	1.29e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HHOLCGFJ_00094	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHOLCGFJ_00095	2.11e-80	-	-	-	S	ko:K15977	-	ko00000	DoxX
HHOLCGFJ_00096	2.07e-79	-	-	-	L	ko:K07496	-	ko00000	Transposase
HHOLCGFJ_00097	1.12e-104	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HHOLCGFJ_00102	1.21e-18	-	-	-	G	ko:K08225	-	ko00000,ko02000	transmembrane transporter activity
HHOLCGFJ_00103	3.89e-99	-	-	-	-	-	-	-	-
HHOLCGFJ_00104	3.58e-74	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHOLCGFJ_00105	2.86e-305	-	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00106	4.27e-311	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHOLCGFJ_00107	7.81e-141	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HHOLCGFJ_00108	6.97e-09	-	-	-	-	-	-	-	-
HHOLCGFJ_00109	3.63e-184	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HHOLCGFJ_00110	6.17e-165	-	-	-	S	-	-	-	Glycosyltransferase like family
HHOLCGFJ_00111	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
HHOLCGFJ_00112	2.87e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HHOLCGFJ_00113	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HHOLCGFJ_00114	8.7e-274	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HHOLCGFJ_00115	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HHOLCGFJ_00116	1.43e-84	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HHOLCGFJ_00117	6.74e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HHOLCGFJ_00118	8.09e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHOLCGFJ_00119	8.98e-149	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HHOLCGFJ_00120	7.2e-200	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HHOLCGFJ_00121	5.64e-125	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HHOLCGFJ_00122	4.75e-216	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HHOLCGFJ_00123	7.34e-83	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHOLCGFJ_00124	8.04e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HHOLCGFJ_00125	2.3e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HHOLCGFJ_00126	3.17e-301	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHOLCGFJ_00127	2.18e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HHOLCGFJ_00128	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HHOLCGFJ_00129	8.52e-305	aceA	4.1.3.1	-	C	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Isocitrate lyase
HHOLCGFJ_00130	1.83e-24	-	-	-	S	-	-	-	YhfH-like protein
HHOLCGFJ_00132	1.64e-154	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HHOLCGFJ_00133	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_00134	8.97e-298	bglH7	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHOLCGFJ_00135	5.7e-272	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHOLCGFJ_00136	6.38e-178	-	-	-	Q	-	-	-	Methyltransferase domain
HHOLCGFJ_00137	6.93e-236	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HHOLCGFJ_00138	1.3e-173	msmR	-	-	K	-	-	-	AraC family transcriptional regulator
HHOLCGFJ_00139	1.75e-228	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HHOLCGFJ_00140	3.1e-214	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HHOLCGFJ_00141	1.85e-58	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
HHOLCGFJ_00142	2.72e-198	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HHOLCGFJ_00143	3.3e-50	-	-	-	-	-	-	-	-
HHOLCGFJ_00144	4.69e-50	-	-	-	-	-	-	-	-
HHOLCGFJ_00146	1.04e-56	-	-	-	-	-	-	-	-
HHOLCGFJ_00147	1.12e-57	-	-	-	-	-	-	-	-
HHOLCGFJ_00149	6.44e-201	-	-	-	-	-	-	-	-
HHOLCGFJ_00150	7.07e-67	-	-	-	-	-	-	-	-
HHOLCGFJ_00151	1.7e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
HHOLCGFJ_00152	1.48e-216	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HHOLCGFJ_00153	8.56e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HHOLCGFJ_00154	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HHOLCGFJ_00155	6.82e-66	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
HHOLCGFJ_00156	2.96e-202	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHOLCGFJ_00157	1.61e-117	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHOLCGFJ_00158	3.14e-179	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HHOLCGFJ_00159	0.0	-	-	-	C	ko:K18218	-	ko00000,ko00002,ko01504,ko02000	Na+/H+ antiporter family
HHOLCGFJ_00160	6.5e-261	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HHOLCGFJ_00161	3.12e-222	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HHOLCGFJ_00162	3.39e-121	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHOLCGFJ_00163	6.09e-67	yutD	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00164	1.79e-59	-	-	-	-	-	-	-	-
HHOLCGFJ_00165	1.65e-102	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HHOLCGFJ_00166	4.63e-174	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHOLCGFJ_00167	1.37e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HHOLCGFJ_00168	2.16e-268	yutH	-	-	S	-	-	-	Spore coat protein
HHOLCGFJ_00169	4.19e-304	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HHOLCGFJ_00170	2.38e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HHOLCGFJ_00171	3.07e-207	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHOLCGFJ_00172	4.25e-49	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HHOLCGFJ_00173	6.51e-69	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00174	0.0	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HHOLCGFJ_00175	3.63e-54	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HHOLCGFJ_00176	9.92e-57	-	-	-	-	-	-	-	-
HHOLCGFJ_00177	5.77e-209	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHOLCGFJ_00178	5.12e-267	mqnE	2.5.1.120	-	H	ko:K18285	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HHOLCGFJ_00179	3.32e-13	-	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HHOLCGFJ_00180	2.5e-79	yutM	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HHOLCGFJ_00181	4.06e-140	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HHOLCGFJ_00182	1.91e-197	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HHOLCGFJ_00183	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HHOLCGFJ_00184	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HHOLCGFJ_00185	4.11e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HHOLCGFJ_00186	3.34e-266	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HHOLCGFJ_00187	3.18e-237	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HHOLCGFJ_00188	1.09e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HHOLCGFJ_00189	2.23e-62	yuiB	-	-	S	-	-	-	Putative membrane protein
HHOLCGFJ_00190	1.2e-145	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00191	2.38e-103	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HHOLCGFJ_00192	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HHOLCGFJ_00193	5.93e-60	-	-	-	-	-	-	-	-
HHOLCGFJ_00194	6.22e-107	-	-	-	L	-	-	-	Transposase IS200 like
HHOLCGFJ_00195	1.56e-296	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HHOLCGFJ_00196	1.81e-55	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHOLCGFJ_00197	6.56e-187	-	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HHOLCGFJ_00198	4.49e-112	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHOLCGFJ_00199	7.3e-111	alaR	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_00200	3.31e-283	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HHOLCGFJ_00201	6.3e-177	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HHOLCGFJ_00202	1.99e-262	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HHOLCGFJ_00203	7.86e-77	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HHOLCGFJ_00204	2.41e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HHOLCGFJ_00205	2.44e-288	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HHOLCGFJ_00206	1.58e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HHOLCGFJ_00207	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HHOLCGFJ_00208	1.77e-93	yugN	-	-	S	-	-	-	YugN-like family
HHOLCGFJ_00209	2.25e-29	-	-	-	-	-	-	-	-
HHOLCGFJ_00211	6.65e-130	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HHOLCGFJ_00216	2.72e-89	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
HHOLCGFJ_00217	1.57e-46	-	-	-	L	-	-	-	phage terminase small subunit
HHOLCGFJ_00218	2.53e-308	-	-	-	S	-	-	-	Terminase
HHOLCGFJ_00219	5.59e-37	-	-	-	-	-	-	-	-
HHOLCGFJ_00220	1.28e-311	-	-	-	S	-	-	-	Phage portal protein
HHOLCGFJ_00221	4.17e-123	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HHOLCGFJ_00222	3.46e-284	-	-	-	S	-	-	-	capsid protein
HHOLCGFJ_00223	5.55e-79	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
HHOLCGFJ_00224	8.52e-60	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HHOLCGFJ_00225	3.27e-74	-	-	-	S	-	-	-	Phage head-tail joining protein
HHOLCGFJ_00226	3.95e-15	-	-	-	S	-	-	-	TIGRFAM phage protein, HK97 gp10 family
HHOLCGFJ_00227	2.63e-71	-	-	-	-	-	-	-	-
HHOLCGFJ_00228	7.83e-138	-	-	-	N	-	-	-	phage major tail protein, phi13 family
HHOLCGFJ_00231	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
HHOLCGFJ_00232	4.95e-192	-	-	-	S	-	-	-	Phage tail protein
HHOLCGFJ_00233	0.0	-	-	-	M	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HHOLCGFJ_00234	0.0	-	-	-	-	-	-	-	-
HHOLCGFJ_00238	9.3e-285	-	-	-	L	-	-	-	Prophage endopeptidase tail
HHOLCGFJ_00240	5.29e-07	-	-	-	S	-	-	-	SPP1 phage holin
HHOLCGFJ_00241	7.43e-100	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HHOLCGFJ_00244	8.55e-81	yqiX	-	-	S	-	-	-	YolD-like protein
HHOLCGFJ_00245	3.23e-29	-	-	-	-	-	-	-	-
HHOLCGFJ_00248	7.05e-112	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Peptidase S24-like
HHOLCGFJ_00249	1.2e-36	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_00251	9.65e-62	-	-	-	-	-	-	-	-
HHOLCGFJ_00253	7.83e-28	-	-	-	-	-	-	-	-
HHOLCGFJ_00254	4.24e-114	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HHOLCGFJ_00256	4.48e-194	-	-	-	D	-	-	-	AAA domain
HHOLCGFJ_00257	3.37e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HHOLCGFJ_00258	0.0	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
HHOLCGFJ_00259	4.73e-81	-	-	-	-	-	-	-	-
HHOLCGFJ_00260	3.17e-124	-	-	-	L	-	-	-	ERCC4 domain
HHOLCGFJ_00261	5.85e-56	-	-	-	-	-	-	-	-
HHOLCGFJ_00262	8.25e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF3797)
HHOLCGFJ_00263	3.14e-46	-	-	-	S	-	-	-	Protein of unknwon function (DUF3310)
HHOLCGFJ_00265	2.99e-90	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
HHOLCGFJ_00266	1.25e-19	-	-	-	S	-	-	-	YopX protein
HHOLCGFJ_00269	5.2e-33	-	-	-	-	-	-	-	-
HHOLCGFJ_00270	7.78e-66	-	-	-	S	-	-	-	Transcriptional regulator
HHOLCGFJ_00272	1.31e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HHOLCGFJ_00273	9.87e-211	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HHOLCGFJ_00274	4.94e-109	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HHOLCGFJ_00275	9.46e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HHOLCGFJ_00276	2.95e-106	-	-	-	S	-	-	-	DinB superfamily
HHOLCGFJ_00277	4.63e-101	-	-	-	S	-	-	-	Putative small multi-drug export protein
HHOLCGFJ_00278	1.85e-302	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHOLCGFJ_00279	2.92e-138	pgpB3	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HHOLCGFJ_00280	1.23e-207	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_00281	1.1e-198	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_00282	8.38e-193	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_00283	1.01e-225	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HHOLCGFJ_00284	9.52e-141	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
HHOLCGFJ_00285	1.52e-154	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HHOLCGFJ_00286	6.97e-150	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HHOLCGFJ_00287	7.78e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HHOLCGFJ_00289	5.16e-110	ywpF	-	-	S	-	-	-	YwpF-like protein
HHOLCGFJ_00290	1.65e-286	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HHOLCGFJ_00291	5.41e-115	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HHOLCGFJ_00292	5.58e-178	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHOLCGFJ_00293	1.14e-175	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HHOLCGFJ_00294	7.17e-233	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HHOLCGFJ_00295	8.15e-198	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HHOLCGFJ_00296	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HHOLCGFJ_00297	1.42e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHOLCGFJ_00298	2.59e-100	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HHOLCGFJ_00299	4.53e-195	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HHOLCGFJ_00300	8.11e-138	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HHOLCGFJ_00301	7.9e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HHOLCGFJ_00303	1.67e-245	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HHOLCGFJ_00304	1.15e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HHOLCGFJ_00305	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HHOLCGFJ_00306	1.08e-307	-	-	-	S	ko:K12941	-	ko00000,ko01002	amidohydrolase
HHOLCGFJ_00307	2.33e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
HHOLCGFJ_00308	9.19e-99	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
HHOLCGFJ_00309	5.51e-85	-	-	-	-	-	-	-	-
HHOLCGFJ_00310	6.12e-265	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HHOLCGFJ_00311	1.12e-291	yhaA1	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HHOLCGFJ_00312	3.75e-94	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HHOLCGFJ_00313	7.05e-216	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HHOLCGFJ_00314	0.0	ytgP	-	-	S	ko:K03328,ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHOLCGFJ_00315	3.03e-258	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HHOLCGFJ_00316	1.8e-269	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HHOLCGFJ_00317	1.28e-172	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HHOLCGFJ_00318	4.69e-43	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HHOLCGFJ_00319	8.58e-103	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HHOLCGFJ_00320	7.14e-190	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHOLCGFJ_00321	2.52e-63	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HHOLCGFJ_00322	6.76e-213	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HHOLCGFJ_00323	1.32e-219	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HHOLCGFJ_00324	1.28e-137	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HHOLCGFJ_00325	1.41e-84	-	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HHOLCGFJ_00326	4.53e-148	cidB	-	-	M	-	-	-	effector of murein hydrolase
HHOLCGFJ_00327	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HHOLCGFJ_00328	4.04e-279	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HHOLCGFJ_00329	5.65e-228	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHOLCGFJ_00330	6.28e-248	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHOLCGFJ_00331	2.24e-282	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHOLCGFJ_00332	5.57e-70	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
HHOLCGFJ_00333	5.2e-167	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_00334	4.39e-211	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HHOLCGFJ_00335	1.35e-198	ytmP	-	-	M	-	-	-	Phosphotransferase
HHOLCGFJ_00337	3.07e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHOLCGFJ_00338	2.23e-65	ytzB	-	-	-	-	-	-	-
HHOLCGFJ_00339	2.61e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HHOLCGFJ_00340	1.86e-116	yjjX	-	-	F	-	-	-	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HHOLCGFJ_00341	9.59e-101	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HHOLCGFJ_00342	2.47e-189	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HHOLCGFJ_00343	6.89e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HHOLCGFJ_00344	2.92e-189	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HHOLCGFJ_00345	1.64e-136	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHOLCGFJ_00346	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HHOLCGFJ_00347	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HHOLCGFJ_00348	1.68e-84	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHOLCGFJ_00349	3.48e-29	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HHOLCGFJ_00350	4.11e-252	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HHOLCGFJ_00351	1.24e-237	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HHOLCGFJ_00352	5.67e-303	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HHOLCGFJ_00353	4.31e-149	acuB	-	-	S	ko:K04767	-	ko00000	Acetoin utilization protein AcuB
HHOLCGFJ_00354	1.41e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HHOLCGFJ_00355	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HHOLCGFJ_00356	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	COG0744 Membrane carboxypeptidase (penicillin-binding protein)
HHOLCGFJ_00357	2.24e-300	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHOLCGFJ_00358	8.51e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHOLCGFJ_00359	2.2e-115	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HHOLCGFJ_00360	3.71e-147	yttP	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_00361	8.97e-191	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HHOLCGFJ_00362	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHOLCGFJ_00363	1.93e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HHOLCGFJ_00364	1.36e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHOLCGFJ_00365	1.17e-38	-	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HHOLCGFJ_00366	2.4e-231	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HHOLCGFJ_00367	1.14e-129	yteJ	-	-	S	-	-	-	RDD family
HHOLCGFJ_00368	5.89e-161	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HHOLCGFJ_00369	1.19e-97	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HHOLCGFJ_00370	8.63e-258	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HHOLCGFJ_00371	9.62e-111	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHOLCGFJ_00372	1.19e-231	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HHOLCGFJ_00373	1.23e-276	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHOLCGFJ_00374	5.8e-219	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
HHOLCGFJ_00376	8.67e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HHOLCGFJ_00377	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HHOLCGFJ_00379	8.7e-179	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_00380	1.35e-85	-	-	-	-	-	-	-	-
HHOLCGFJ_00381	3.91e-269	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HHOLCGFJ_00382	1.45e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HHOLCGFJ_00384	2.37e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HHOLCGFJ_00385	3.35e-11	ytpI	-	-	S	-	-	-	YtpI-like protein
HHOLCGFJ_00386	7.67e-223	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HHOLCGFJ_00387	1.03e-117	ytrI	-	-	-	-	-	-	-
HHOLCGFJ_00388	4.62e-70	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HHOLCGFJ_00389	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HHOLCGFJ_00390	1.04e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HHOLCGFJ_00391	1.01e-149	lutR_1	-	-	K	ko:K05799	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HHOLCGFJ_00392	9.45e-198	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHOLCGFJ_00393	1.68e-229	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HHOLCGFJ_00394	1.14e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHOLCGFJ_00395	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HHOLCGFJ_00396	9.31e-84	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HHOLCGFJ_00397	4.98e-96	-	-	-	S	-	-	-	UPF0756 membrane protein
HHOLCGFJ_00398	1.53e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HHOLCGFJ_00399	1.08e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HHOLCGFJ_00400	7.32e-219	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HHOLCGFJ_00401	1.16e-97	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
HHOLCGFJ_00402	1.14e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_00403	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HHOLCGFJ_00404	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHOLCGFJ_00405	7.85e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHOLCGFJ_00406	3.68e-136	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HHOLCGFJ_00407	2.44e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHOLCGFJ_00408	4.26e-249	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHOLCGFJ_00409	2.59e-89	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HHOLCGFJ_00410	6.77e-87	-	-	-	-	-	-	-	-
HHOLCGFJ_00411	1.52e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHOLCGFJ_00412	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HHOLCGFJ_00413	1.48e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HHOLCGFJ_00414	2.85e-287	mqnC	1.21.98.1	-	H	ko:K11784	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
HHOLCGFJ_00415	1.16e-208	ytxC	-	-	S	-	-	-	YtxC-like family
HHOLCGFJ_00416	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHOLCGFJ_00417	8.16e-241	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HHOLCGFJ_00418	3.98e-229	-	-	-	C	-	-	-	Aldo/keto reductase family
HHOLCGFJ_00419	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HHOLCGFJ_00420	8.9e-168	-	-	-	-	-	-	-	-
HHOLCGFJ_00421	7.63e-305	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHOLCGFJ_00422	2.79e-153	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_00423	1.48e-269	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HHOLCGFJ_00424	4.04e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHOLCGFJ_00425	7.54e-40	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HHOLCGFJ_00426	5.42e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHOLCGFJ_00427	9.32e-70	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
HHOLCGFJ_00428	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHOLCGFJ_00429	7.91e-86	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HHOLCGFJ_00430	1.84e-260	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HHOLCGFJ_00431	1.02e-22	-	-	-	-	-	-	-	-
HHOLCGFJ_00433	3.13e-42	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HHOLCGFJ_00434	5.88e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHOLCGFJ_00435	8.23e-247	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHOLCGFJ_00436	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHOLCGFJ_00437	6.35e-46	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HHOLCGFJ_00438	5.01e-118	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HHOLCGFJ_00439	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HHOLCGFJ_00440	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHOLCGFJ_00441	7.25e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HHOLCGFJ_00442	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHOLCGFJ_00443	6.25e-134	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_00444	3.4e-179	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HHOLCGFJ_00445	4.25e-173	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HHOLCGFJ_00446	1.13e-223	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HHOLCGFJ_00447	1.37e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HHOLCGFJ_00448	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHOLCGFJ_00449	7.17e-99	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HHOLCGFJ_00450	1.82e-295	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HHOLCGFJ_00451	5.12e-145	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HHOLCGFJ_00452	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HHOLCGFJ_00453	4.17e-186	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HHOLCGFJ_00454	2.63e-104	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HHOLCGFJ_00455	2.77e-45	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_00456	2.33e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HHOLCGFJ_00457	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHOLCGFJ_00458	4e-105	ysmB	-	-	K	-	-	-	transcriptional
HHOLCGFJ_00459	5.24e-193	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HHOLCGFJ_00460	3.13e-42	-	-	-	C	-	-	-	4Fe-4S binding domain
HHOLCGFJ_00461	3.77e-250	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HHOLCGFJ_00462	4.75e-249	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HHOLCGFJ_00463	5.64e-175	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HHOLCGFJ_00464	4.93e-141	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHOLCGFJ_00465	6.48e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HHOLCGFJ_00468	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HHOLCGFJ_00469	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HHOLCGFJ_00470	8.81e-98	-	-	-	-	-	-	-	-
HHOLCGFJ_00471	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HHOLCGFJ_00472	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HHOLCGFJ_00473	3.04e-111	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HHOLCGFJ_00474	2.5e-235	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HHOLCGFJ_00475	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HHOLCGFJ_00476	3.13e-252	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HHOLCGFJ_00477	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHOLCGFJ_00478	2.02e-144	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHOLCGFJ_00479	4.45e-230	ysoA	-	-	O	-	-	-	COG0457 FOG TPR repeat
HHOLCGFJ_00480	2.3e-294	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHOLCGFJ_00481	2.85e-303	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHOLCGFJ_00482	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HHOLCGFJ_00483	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HHOLCGFJ_00484	2.65e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HHOLCGFJ_00485	0.0	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HHOLCGFJ_00486	6.33e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HHOLCGFJ_00487	2.26e-216	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HHOLCGFJ_00488	1.44e-178	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HHOLCGFJ_00489	4e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HHOLCGFJ_00490	2.13e-313	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HHOLCGFJ_00491	4.16e-243	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HHOLCGFJ_00492	5.55e-211	-	-	-	-	-	-	-	-
HHOLCGFJ_00493	3.09e-245	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HHOLCGFJ_00494	5.5e-149	-	-	-	-	-	-	-	-
HHOLCGFJ_00495	2.36e-42	-	-	-	-	-	-	-	-
HHOLCGFJ_00496	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHOLCGFJ_00497	7.36e-308	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HHOLCGFJ_00498	2.26e-155	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HHOLCGFJ_00499	2.89e-252	-	-	-	-	ko:K06380	-	ko00000	-
HHOLCGFJ_00500	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HHOLCGFJ_00501	4.42e-136	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HHOLCGFJ_00502	2.48e-157	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HHOLCGFJ_00503	4.89e-239	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HHOLCGFJ_00504	1.02e-203	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HHOLCGFJ_00505	1.48e-103	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HHOLCGFJ_00506	3.82e-157	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HHOLCGFJ_00507	6.84e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HHOLCGFJ_00508	4.46e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HHOLCGFJ_00509	2.17e-97	-	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaC family
HHOLCGFJ_00510	2.86e-121	-	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HHOLCGFJ_00511	1.48e-218	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HHOLCGFJ_00512	7.8e-169	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HHOLCGFJ_00513	7.19e-198	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HHOLCGFJ_00514	0.0	cafA	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	ribonuclease, Rne Rng family
HHOLCGFJ_00515	5.22e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HHOLCGFJ_00516	5.37e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HHOLCGFJ_00517	1.58e-59	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HHOLCGFJ_00518	2.47e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	SpoVT / AbrB like domain
HHOLCGFJ_00519	7.66e-273	-	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
HHOLCGFJ_00521	2.15e-152	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HHOLCGFJ_00522	3.51e-274	-	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HHOLCGFJ_00523	4.15e-171	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HHOLCGFJ_00524	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HHOLCGFJ_00525	6.86e-108	-	-	-	S	-	-	-	DinB family
HHOLCGFJ_00526	1.04e-214	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HHOLCGFJ_00527	4.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HHOLCGFJ_00528	2.52e-205	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HHOLCGFJ_00529	3.69e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHOLCGFJ_00530	1.5e-184	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHOLCGFJ_00531	6.09e-144	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HHOLCGFJ_00532	4.58e-82	-	-	-	-	-	-	-	-
HHOLCGFJ_00533	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	exonuclease activity
HHOLCGFJ_00534	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HHOLCGFJ_00535	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HHOLCGFJ_00536	1.74e-96	cheW	-	-	NT	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	chemotaxis
HHOLCGFJ_00537	0.0	asnH	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HHOLCGFJ_00538	1.53e-62	-	-	-	S	-	-	-	IDEAL
HHOLCGFJ_00539	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HHOLCGFJ_00541	2.88e-130	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HHOLCGFJ_00542	7.4e-93	yxxG	-	-	-	-	-	-	-
HHOLCGFJ_00544	6.94e-200	ykgA	-	-	E	-	-	-	Amidinotransferase
HHOLCGFJ_00545	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HHOLCGFJ_00546	2.04e-118	-	-	-	-	-	-	-	-
HHOLCGFJ_00547	2.36e-84	ytwF	-	-	P	-	-	-	Sulfurtransferase
HHOLCGFJ_00548	1.01e-56	-	-	-	-	-	-	-	-
HHOLCGFJ_00549	9.1e-191	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HHOLCGFJ_00550	7.65e-188	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HHOLCGFJ_00551	6.44e-18	-	-	-	S	-	-	-	Intracellular proteinase inhibitor
HHOLCGFJ_00553	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HHOLCGFJ_00554	3.4e-295	ywqB	-	-	S	-	-	-	zinc ion binding
HHOLCGFJ_00555	1.78e-140	-	-	-	-	-	-	-	-
HHOLCGFJ_00556	2.72e-102	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_00557	1.57e-195	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HHOLCGFJ_00558	1.17e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HHOLCGFJ_00559	3.4e-255	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHOLCGFJ_00560	1.32e-289	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HHOLCGFJ_00561	1.13e-173	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HHOLCGFJ_00562	7.44e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HHOLCGFJ_00563	2.17e-266	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HHOLCGFJ_00564	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HHOLCGFJ_00565	2.19e-220	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHOLCGFJ_00566	6.55e-155	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HHOLCGFJ_00567	5.73e-203	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HHOLCGFJ_00568	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHOLCGFJ_00569	7.3e-19	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	Competence protein ComG
HHOLCGFJ_00571	4.37e-214	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHOLCGFJ_00572	1.28e-294	fabF	2.3.1.179	-	I	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHOLCGFJ_00573	0.0	-	-	-	-	-	-	-	-
HHOLCGFJ_00574	0.0	-	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Poly A polymerase head domain
HHOLCGFJ_00576	1.16e-134	-	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HHOLCGFJ_00577	3.94e-172	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HHOLCGFJ_00578	1.28e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HHOLCGFJ_00579	1.49e-176	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HHOLCGFJ_00580	8.47e-201	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HHOLCGFJ_00581	8.42e-185	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HHOLCGFJ_00582	1.94e-15	-	-	-	-	-	-	-	-
HHOLCGFJ_00583	6.64e-234	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HHOLCGFJ_00585	4.41e-137	-	-	-	CO	-	-	-	Redoxin
HHOLCGFJ_00586	1.5e-128	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HHOLCGFJ_00587	1.5e-144	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HHOLCGFJ_00588	1.83e-12	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HHOLCGFJ_00589	1.58e-301	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HHOLCGFJ_00590	2.05e-127	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHOLCGFJ_00592	2.03e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHOLCGFJ_00593	5.5e-148	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HHOLCGFJ_00594	5.05e-303	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HHOLCGFJ_00596	3.13e-222	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HHOLCGFJ_00597	1.67e-95	yjbI	-	-	S	ko:K06886	-	ko00000	COG2346 Truncated hemoglobins
HHOLCGFJ_00598	1.35e-141	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HHOLCGFJ_00599	7.94e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00600	3.74e-82	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HHOLCGFJ_00601	1.02e-142	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HHOLCGFJ_00602	5.27e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHOLCGFJ_00603	3.24e-220	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HHOLCGFJ_00604	1.74e-178	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HHOLCGFJ_00605	7.52e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HHOLCGFJ_00606	2.72e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HHOLCGFJ_00607	6.08e-163	-	-	-	-	-	-	-	-
HHOLCGFJ_00608	1.77e-176	-	-	-	-	-	-	-	-
HHOLCGFJ_00610	6.94e-07	-	-	-	-	-	-	-	-
HHOLCGFJ_00611	1.03e-107	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HHOLCGFJ_00612	4.39e-97	-	-	-	-	-	-	-	-
HHOLCGFJ_00613	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HHOLCGFJ_00614	2.24e-238	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHOLCGFJ_00615	2.73e-241	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HHOLCGFJ_00625	3.58e-55	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HHOLCGFJ_00626	1.22e-64	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HHOLCGFJ_00627	1.65e-97	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HHOLCGFJ_00629	4.4e-106	-	-	-	-	-	-	-	-
HHOLCGFJ_00632	2.65e-48	B4168_0554	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HHOLCGFJ_00633	7.55e-155	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HHOLCGFJ_00635	3.45e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HHOLCGFJ_00636	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HHOLCGFJ_00637	6.95e-262	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HHOLCGFJ_00638	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HHOLCGFJ_00639	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HHOLCGFJ_00640	4.68e-82	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HHOLCGFJ_00641	6.16e-197	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HHOLCGFJ_00642	0.0	uvrD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HHOLCGFJ_00643	1.03e-203	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HHOLCGFJ_00644	5.42e-255	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HHOLCGFJ_00645	6.58e-101	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HHOLCGFJ_00646	1.47e-213	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HHOLCGFJ_00647	2.46e-79	-	-	-	-	-	-	-	-
HHOLCGFJ_00648	4.42e-116	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HHOLCGFJ_00649	5.61e-251	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HHOLCGFJ_00650	7.96e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHOLCGFJ_00651	3.54e-128	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HHOLCGFJ_00652	9.91e-68	-	-	-	S	-	-	-	YfzA-like protein
HHOLCGFJ_00653	3.84e-48	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HHOLCGFJ_00654	2.02e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HHOLCGFJ_00655	6.16e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HHOLCGFJ_00656	1.98e-40	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HHOLCGFJ_00657	6.3e-54	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HHOLCGFJ_00658	1.51e-262	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HHOLCGFJ_00659	1.39e-121	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HHOLCGFJ_00660	1.05e-146	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HHOLCGFJ_00661	2.98e-117	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HHOLCGFJ_00662	3.08e-74	-	-	-	-	-	-	-	-
HHOLCGFJ_00663	7.32e-105	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHOLCGFJ_00664	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HHOLCGFJ_00665	5.96e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00666	1.42e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHOLCGFJ_00667	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHOLCGFJ_00668	2.03e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHOLCGFJ_00669	2.81e-202	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HHOLCGFJ_00670	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHOLCGFJ_00671	2.32e-193	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HHOLCGFJ_00672	6.48e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HHOLCGFJ_00673	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HHOLCGFJ_00674	9.21e-305	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HHOLCGFJ_00675	8.04e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HHOLCGFJ_00676	4.19e-154	-	-	-	M	-	-	-	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHOLCGFJ_00677	3.32e-48	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HHOLCGFJ_00678	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HHOLCGFJ_00679	3.58e-263	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HHOLCGFJ_00680	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHOLCGFJ_00681	2.17e-241	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHOLCGFJ_00682	4e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHOLCGFJ_00683	8.99e-293	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHOLCGFJ_00684	2.91e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HHOLCGFJ_00685	3.38e-77	-	-	-	-	-	-	-	-
HHOLCGFJ_00687	2.14e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HHOLCGFJ_00688	1.66e-42	-	-	-	-	-	-	-	-
HHOLCGFJ_00689	1.16e-62	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HHOLCGFJ_00690	9.47e-39	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
HHOLCGFJ_00691	1.62e-128	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HHOLCGFJ_00693	7.03e-246	-	-	-	C	-	-	-	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HHOLCGFJ_00694	2.72e-289	-	-	-	E	-	-	-	Peptidase family M28
HHOLCGFJ_00695	2.99e-144	yhfK	-	-	GM	-	-	-	NmrA-like family
HHOLCGFJ_00696	3.27e-237	ytvI	-	-	S	-	-	-	AI-2E family transporter
HHOLCGFJ_00697	2.24e-125	copC	-	-	S	ko:K07156	-	ko00000,ko02000	CopC domain
HHOLCGFJ_00699	1.89e-254	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HHOLCGFJ_00700	1.79e-243	-	-	-	T	-	-	-	Metal dependent phosphohydrolases with conserved 'HD' motif.
HHOLCGFJ_00701	5.28e-188	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HHOLCGFJ_00702	2.79e-115	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHOLCGFJ_00703	9.3e-292	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HHOLCGFJ_00704	1.96e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHOLCGFJ_00705	1.46e-50	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HHOLCGFJ_00706	2.18e-172	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HHOLCGFJ_00707	3.15e-131	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
HHOLCGFJ_00708	1.25e-107	ykuV	-	-	CO	-	-	-	thiol-disulfide
HHOLCGFJ_00709	6.6e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HHOLCGFJ_00710	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHOLCGFJ_00711	4.45e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HHOLCGFJ_00712	2.58e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHOLCGFJ_00713	1.8e-33	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HHOLCGFJ_00714	8.8e-133	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HHOLCGFJ_00715	3.83e-256	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHOLCGFJ_00716	1.5e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHOLCGFJ_00717	6.67e-248	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHOLCGFJ_00718	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHOLCGFJ_00719	3.07e-239	appD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_00720	5.5e-238	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_00721	0.0	appA_2	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HHOLCGFJ_00722	3.37e-223	-	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_00723	8.8e-210	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_00724	8.05e-88	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
HHOLCGFJ_00725	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HHOLCGFJ_00726	2.93e-194	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HHOLCGFJ_00727	1.06e-298	-	-	-	O	-	-	-	Peptidase family M48
HHOLCGFJ_00728	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HHOLCGFJ_00729	6.3e-55	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HHOLCGFJ_00730	1.71e-152	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HHOLCGFJ_00731	3.73e-198	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HHOLCGFJ_00732	3.34e-212	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HHOLCGFJ_00733	1.13e-17	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HHOLCGFJ_00734	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HHOLCGFJ_00735	3.25e-70	ylaH	-	-	S	-	-	-	YlaH-like protein
HHOLCGFJ_00736	1.3e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00737	0.0	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HHOLCGFJ_00738	6.72e-123	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HHOLCGFJ_00739	1.92e-56	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HHOLCGFJ_00740	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HHOLCGFJ_00741	6.42e-205	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HHOLCGFJ_00742	4.12e-254	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HHOLCGFJ_00743	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHOLCGFJ_00744	8.77e-144	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HHOLCGFJ_00745	7.24e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HHOLCGFJ_00746	1.13e-120	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HHOLCGFJ_00747	2.37e-110	-	-	-	-	-	-	-	-
HHOLCGFJ_00748	1.34e-83	ylbA	-	-	S	-	-	-	YugN-like family
HHOLCGFJ_00749	2.2e-272	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HHOLCGFJ_00750	2.89e-110	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein, possibly involved in aromatic compounds catabolism
HHOLCGFJ_00751	5.03e-95	ylbD	-	-	S	-	-	-	Putative coat protein
HHOLCGFJ_00752	7.5e-43	ylbE	-	-	S	-	-	-	YlbE-like protein
HHOLCGFJ_00753	5.24e-183	-	-	-	HJ	ko:K05844	-	ko00000,ko01000,ko03009	Prokaryotic glutathione synthetase, ATP-grasp domain
HHOLCGFJ_00754	4.07e-92	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HHOLCGFJ_00755	4.89e-63	ylbG	-	-	S	-	-	-	UPF0298 protein
HHOLCGFJ_00756	3.58e-85	-	-	-	S	-	-	-	Methylthioribose kinase
HHOLCGFJ_00757	8.32e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HHOLCGFJ_00758	1.28e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHOLCGFJ_00759	3.72e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HHOLCGFJ_00760	1e-178	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HHOLCGFJ_00761	4.78e-249	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HHOLCGFJ_00762	1.61e-293	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HHOLCGFJ_00763	4.91e-121	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HHOLCGFJ_00764	7.12e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HHOLCGFJ_00765	1.9e-103	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HHOLCGFJ_00766	2.19e-121	ylbP	-	-	K	-	-	-	n-acetyltransferase
HHOLCGFJ_00767	6.18e-206	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHOLCGFJ_00769	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HHOLCGFJ_00770	4.81e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HHOLCGFJ_00771	7.63e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHOLCGFJ_00772	3.1e-69	ftsL	-	-	D	-	-	-	cell division protein FtsL
HHOLCGFJ_00773	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HHOLCGFJ_00774	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HHOLCGFJ_00775	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHOLCGFJ_00776	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHOLCGFJ_00777	9.92e-218	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHOLCGFJ_00778	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHOLCGFJ_00779	5.14e-247	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HHOLCGFJ_00780	3.65e-173	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHOLCGFJ_00782	1.02e-295	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHOLCGFJ_00783	4.15e-241	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHOLCGFJ_00784	4.54e-209	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HHOLCGFJ_00785	8.95e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHOLCGFJ_00786	3.67e-181	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHOLCGFJ_00787	6.23e-62	ylmC	-	-	S	-	-	-	sporulation protein
HHOLCGFJ_00788	6.52e-190	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HHOLCGFJ_00789	3.51e-154	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHOLCGFJ_00790	2.04e-94	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHOLCGFJ_00791	7.03e-58	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HHOLCGFJ_00792	7.72e-179	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HHOLCGFJ_00793	2.64e-96	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HHOLCGFJ_00794	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHOLCGFJ_00795	9.51e-148	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HHOLCGFJ_00796	8.13e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHOLCGFJ_00797	2.2e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HHOLCGFJ_00798	2.85e-135	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHOLCGFJ_00799	7.11e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HHOLCGFJ_00800	9.18e-211	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HHOLCGFJ_00801	1.68e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHOLCGFJ_00802	2.97e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HHOLCGFJ_00803	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HHOLCGFJ_00804	5.05e-187	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HHOLCGFJ_00805	1.04e-213	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHOLCGFJ_00806	5.62e-165	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHOLCGFJ_00807	7.28e-142	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHOLCGFJ_00808	2.31e-156	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HHOLCGFJ_00810	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HHOLCGFJ_00811	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HHOLCGFJ_00812	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HHOLCGFJ_00813	1.15e-52	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HHOLCGFJ_00814	3.88e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HHOLCGFJ_00815	5.59e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHOLCGFJ_00816	1.69e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHOLCGFJ_00817	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHOLCGFJ_00818	1.43e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHOLCGFJ_00819	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHOLCGFJ_00820	5.6e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HHOLCGFJ_00821	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HHOLCGFJ_00822	3.47e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHOLCGFJ_00823	4.5e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HHOLCGFJ_00824	4.09e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HHOLCGFJ_00825	1.81e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00826	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HHOLCGFJ_00827	1.68e-194	yitS	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_00828	2.23e-157	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HHOLCGFJ_00829	1.55e-195	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HHOLCGFJ_00830	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHOLCGFJ_00831	1.53e-127	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HHOLCGFJ_00832	3.16e-232	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHOLCGFJ_00833	6.5e-219	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
HHOLCGFJ_00834	2.98e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HHOLCGFJ_00835	1.35e-42	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHOLCGFJ_00836	1.55e-177	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHOLCGFJ_00837	2.38e-14	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HHOLCGFJ_00838	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HHOLCGFJ_00839	3.38e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHOLCGFJ_00840	3.83e-68	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHOLCGFJ_00841	5.06e-314	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHOLCGFJ_00842	7.93e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HHOLCGFJ_00843	9.51e-47	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HHOLCGFJ_00844	2.5e-90	-	-	-	S	-	-	-	YlqD protein
HHOLCGFJ_00845	6.52e-124	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHOLCGFJ_00846	1.76e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HHOLCGFJ_00847	0.0	-	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
HHOLCGFJ_00848	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHOLCGFJ_00849	1.1e-10	-	-	-	-	-	-	-	-
HHOLCGFJ_00850	7.13e-134	sipS	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HHOLCGFJ_00851	4.19e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHOLCGFJ_00852	2.38e-178	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHOLCGFJ_00854	4.59e-103	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	FlhB HrpN YscU SpaS Family
HHOLCGFJ_00855	5.15e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HHOLCGFJ_00856	1.79e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHOLCGFJ_00857	8.46e-221	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HHOLCGFJ_00858	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHOLCGFJ_00859	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HHOLCGFJ_00860	7.91e-216	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HHOLCGFJ_00861	1.05e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HHOLCGFJ_00862	7.5e-301	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HHOLCGFJ_00863	2.27e-174	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HHOLCGFJ_00864	2.47e-88	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HHOLCGFJ_00865	3.75e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HHOLCGFJ_00866	9.59e-57	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HHOLCGFJ_00867	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HHOLCGFJ_00868	1.32e-227	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HHOLCGFJ_00869	6.63e-110	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HHOLCGFJ_00870	9.78e-312	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HHOLCGFJ_00871	6.23e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HHOLCGFJ_00873	0.0	-	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein FliK
HHOLCGFJ_00874	4.43e-95	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HHOLCGFJ_00875	6.89e-189	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HHOLCGFJ_00876	3.08e-38	flbD	-	-	N	ko:K02385	-	ko00000,ko02035	protein, possibly involved in motility
HHOLCGFJ_00877	1.61e-92	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HHOLCGFJ_00878	1.13e-225	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HHOLCGFJ_00879	5.01e-274	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHOLCGFJ_00880	2.57e-78	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HHOLCGFJ_00881	1.04e-140	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HHOLCGFJ_00882	1.04e-145	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HHOLCGFJ_00883	8.01e-54	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HHOLCGFJ_00884	1.93e-171	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HHOLCGFJ_00885	1.3e-243	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHOLCGFJ_00886	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHOLCGFJ_00887	3.28e-232	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HHOLCGFJ_00888	4.39e-127	-	-	-	-	-	-	-	-
HHOLCGFJ_00889	2.11e-220	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HHOLCGFJ_00890	3.87e-141	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HHOLCGFJ_00891	7.7e-110	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HHOLCGFJ_00892	7.05e-171	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHOLCGFJ_00894	5.65e-171	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HHOLCGFJ_00895	5.04e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHOLCGFJ_00896	1.18e-160	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HHOLCGFJ_00897	7.56e-116	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHOLCGFJ_00898	2.61e-188	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHOLCGFJ_00899	7.6e-176	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HHOLCGFJ_00900	5.53e-265	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HHOLCGFJ_00901	3.42e-297	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HHOLCGFJ_00902	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHOLCGFJ_00903	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHOLCGFJ_00904	3.83e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HHOLCGFJ_00905	3.99e-257	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HHOLCGFJ_00906	1.42e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HHOLCGFJ_00907	2.49e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HHOLCGFJ_00908	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHOLCGFJ_00909	5.12e-56	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HHOLCGFJ_00910	2.49e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHOLCGFJ_00911	6.31e-223	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHOLCGFJ_00912	6.07e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HHOLCGFJ_00913	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHOLCGFJ_00914	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HHOLCGFJ_00915	1.36e-244	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HHOLCGFJ_00916	1.81e-290	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HHOLCGFJ_00917	5.31e-49	ymxH	-	-	S	-	-	-	YlmC YmxH family
HHOLCGFJ_00918	3.31e-205	spoVFA	-	-	E	ko:K06410	-	ko00000	subunit a
HHOLCGFJ_00919	3.23e-139	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HHOLCGFJ_00920	8.86e-245	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHOLCGFJ_00921	1.52e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HHOLCGFJ_00922	1.26e-210	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHOLCGFJ_00923	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHOLCGFJ_00924	3.79e-165	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HHOLCGFJ_00925	3.72e-06	-	-	-	S	-	-	-	YlzJ-like protein
HHOLCGFJ_00926	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HHOLCGFJ_00927	2.49e-167	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_00928	2.01e-304	albE	-	-	S	-	-	-	Peptidase M16
HHOLCGFJ_00929	0.0	ymfH	-	-	S	-	-	-	zinc protease
HHOLCGFJ_00930	1.81e-160	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_00931	3.99e-53	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HHOLCGFJ_00932	5.43e-180	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HHOLCGFJ_00933	1.58e-188	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HHOLCGFJ_00934	2.85e-128	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHOLCGFJ_00935	7.13e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HHOLCGFJ_00936	0.0	deaD	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHOLCGFJ_00937	1.47e-243	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHOLCGFJ_00938	1.41e-240	-	-	-	L	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HHOLCGFJ_00939	0.0	-	-	-	L	-	-	-	AAA domain
HHOLCGFJ_00940	1.02e-10	-	-	-	-	-	-	-	-
HHOLCGFJ_00941	7.7e-149	-	-	-	L	-	-	-	DNA recombination
HHOLCGFJ_00942	3.12e-292	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HHOLCGFJ_00943	8.12e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HHOLCGFJ_00944	7.82e-51	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HHOLCGFJ_00945	7.83e-200	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HHOLCGFJ_00946	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HHOLCGFJ_00947	1.1e-88	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HHOLCGFJ_00948	1.13e-133	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HHOLCGFJ_00949	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHOLCGFJ_00950	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHOLCGFJ_00951	2.05e-180	-	-	-	J	-	-	-	Putative SAM-dependent methyltransferase
HHOLCGFJ_00952	5e-224	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHOLCGFJ_00953	1.24e-47	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HHOLCGFJ_00954	3.91e-245	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HHOLCGFJ_00955	2.02e-220	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HHOLCGFJ_00956	1.24e-314	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HHOLCGFJ_00957	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HHOLCGFJ_00958	5.69e-100	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_00959	0.0	-	-	-	C	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	FAD binding domain
HHOLCGFJ_00960	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HHOLCGFJ_00961	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HHOLCGFJ_00962	0.0	glcB	2.3.3.9	-	C	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HHOLCGFJ_00963	5.46e-184	-	-	-	Q	-	-	-	Domain of unknown function (DUF2437)
HHOLCGFJ_00964	2.49e-177	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
HHOLCGFJ_00965	2.7e-115	-	-	-	-	-	-	-	-
HHOLCGFJ_00966	2.93e-125	-	-	-	FG	-	-	-	Domain of unknown function (DUF4269)
HHOLCGFJ_00967	2.2e-273	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHOLCGFJ_00969	4.36e-283	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HHOLCGFJ_00970	8.11e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHOLCGFJ_00972	8.37e-153	yneB	-	-	L	-	-	-	resolvase
HHOLCGFJ_00973	2.51e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
HHOLCGFJ_00974	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHOLCGFJ_00975	2.69e-95	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HHOLCGFJ_00976	8.21e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HHOLCGFJ_00977	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HHOLCGFJ_00978	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HHOLCGFJ_00979	2.41e-106	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HHOLCGFJ_00980	3.83e-19	-	-	-	-	-	-	-	-
HHOLCGFJ_00982	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHOLCGFJ_00983	2.3e-06	-	-	-	S	-	-	-	Fur-regulated basic protein B
HHOLCGFJ_00984	3.93e-17	sspN	-	-	S	ko:K06431	-	ko00000	Small acid-soluble spore protein N family
HHOLCGFJ_00985	9.69e-182	-	-	-	P	ko:K07245	-	ko00000,ko02000	Copper resistance protein D
HHOLCGFJ_00986	0.0	spoVK_1	-	-	O	-	-	-	stage V sporulation protein K
HHOLCGFJ_00987	1.02e-98	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HHOLCGFJ_00988	8.79e-199	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHOLCGFJ_00989	4.11e-105	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HHOLCGFJ_00990	2.03e-230	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HHOLCGFJ_00991	3.44e-200	-	-	-	I	-	-	-	Hydrolase
HHOLCGFJ_00992	3.02e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HHOLCGFJ_00993	1.81e-31	-	-	-	-	-	-	-	-
HHOLCGFJ_00994	1.03e-47	-	-	-	S	-	-	-	YppG-like protein
HHOLCGFJ_00995	7.75e-94	hspX	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HHOLCGFJ_00996	3.8e-222	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
HHOLCGFJ_00997	6.44e-206	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HHOLCGFJ_00999	7.35e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HHOLCGFJ_01000	2.03e-124	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHOLCGFJ_01001	5.25e-279	-	-	-	I	ko:K01066	-	ko00000,ko01000	COG0657 Esterase lipase
HHOLCGFJ_01002	3.94e-58	-	-	-	S	-	-	-	DNA alkylation repair protein
HHOLCGFJ_01003	7.16e-236	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HHOLCGFJ_01004	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHOLCGFJ_01005	4.91e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HHOLCGFJ_01006	2.19e-67	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HHOLCGFJ_01007	5.71e-58	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HHOLCGFJ_01008	1.95e-57	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HHOLCGFJ_01009	0.0	agcS	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HHOLCGFJ_01010	7.49e-301	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HHOLCGFJ_01011	8.12e-165	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HHOLCGFJ_01012	4.65e-100	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HHOLCGFJ_01013	1.51e-161	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HHOLCGFJ_01014	1.13e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HHOLCGFJ_01016	1.24e-137	-	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HHOLCGFJ_01017	1.98e-259	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_01018	3.25e-154	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HHOLCGFJ_01019	3.22e-162	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HHOLCGFJ_01020	1.58e-221	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HHOLCGFJ_01022	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHOLCGFJ_01023	1.36e-100	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HHOLCGFJ_01025	3.88e-153	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	lytic transglycosylase activity
HHOLCGFJ_01026	1.91e-261	-	-	-	Q	-	-	-	O-methyltransferase
HHOLCGFJ_01028	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HHOLCGFJ_01029	2.1e-260	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HHOLCGFJ_01030	9.15e-45	yozC	-	-	-	-	-	-	-
HHOLCGFJ_01031	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHOLCGFJ_01032	2.25e-202	yvgN	-	-	S	-	-	-	reductase
HHOLCGFJ_01033	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HHOLCGFJ_01034	5.52e-75	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HHOLCGFJ_01035	1.09e-118	yocC	-	-	-	-	-	-	-
HHOLCGFJ_01036	1.07e-134	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_01037	2.65e-215	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
HHOLCGFJ_01038	1.15e-160	bshB2	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HHOLCGFJ_01039	9.83e-81	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HHOLCGFJ_01040	3.41e-148	mucD	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHOLCGFJ_01041	1.92e-92	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HHOLCGFJ_01043	8.51e-306	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HHOLCGFJ_01044	4.4e-305	-	-	-	S	-	-	-	membrane
HHOLCGFJ_01046	7.8e-31	-	-	-	-	-	-	-	-
HHOLCGFJ_01047	6.33e-30	-	-	-	UW	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
HHOLCGFJ_01048	3.74e-69	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_01049	1.35e-158	-	-	-	-	-	-	-	-
HHOLCGFJ_01050	8.77e-135	-	-	-	-	-	-	-	-
HHOLCGFJ_01051	3.61e-77	-	-	-	-	-	-	-	-
HHOLCGFJ_01052	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HHOLCGFJ_01053	4.45e-128	-	-	-	S	-	-	-	DinB superfamily
HHOLCGFJ_01054	8.62e-81	-	-	-	-	-	-	-	-
HHOLCGFJ_01055	3.29e-181	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HHOLCGFJ_01056	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_01057	0.0	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
HHOLCGFJ_01058	1.8e-164	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HHOLCGFJ_01060	1.75e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HHOLCGFJ_01061	1.48e-22	-	-	-	-	-	-	-	-
HHOLCGFJ_01062	4.03e-23	-	-	-	-	-	-	-	-
HHOLCGFJ_01064	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HHOLCGFJ_01065	7.45e-179	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
HHOLCGFJ_01066	0.0	glvA	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHOLCGFJ_01067	3.39e-165	-	-	-	K	ko:K11922	-	ko00000,ko03000	UTRA
HHOLCGFJ_01068	1.7e-148	-	-	-	S	-	-	-	CAAX protease self-immunity
HHOLCGFJ_01069	7.35e-252	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HHOLCGFJ_01070	2.66e-215	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HHOLCGFJ_01071	1.02e-194	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HHOLCGFJ_01072	4.17e-37	-	-	-	-	-	-	-	-
HHOLCGFJ_01073	1.06e-166	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HHOLCGFJ_01074	5.73e-256	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HHOLCGFJ_01075	1.37e-268	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHOLCGFJ_01076	1.1e-228	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHOLCGFJ_01077	2.4e-195	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HHOLCGFJ_01078	1.67e-218	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HHOLCGFJ_01079	8.4e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HHOLCGFJ_01080	2.31e-229	-	-	-	S	-	-	-	Tetratricopeptide repeat
HHOLCGFJ_01081	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HHOLCGFJ_01082	7.66e-316	mtaD	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HHOLCGFJ_01084	8.74e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HHOLCGFJ_01085	2.1e-109	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_01086	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HHOLCGFJ_01087	6.12e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HHOLCGFJ_01088	2.51e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHOLCGFJ_01089	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HHOLCGFJ_01090	1.99e-199	ssuB	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HHOLCGFJ_01091	2.49e-134	ssuC_2	-	-	P	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_01092	6.3e-224	ssuA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HHOLCGFJ_01093	6.95e-122	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHOLCGFJ_01094	2.44e-104	yybA	-	-	K	-	-	-	transcriptional
HHOLCGFJ_01095	4.23e-123	-	-	-	S	-	-	-	VanZ like family
HHOLCGFJ_01096	1.95e-158	-	-	-	-	-	-	-	-
HHOLCGFJ_01097	2.05e-51	-	-	-	G	-	-	-	PTS HPr component phosphorylation site
HHOLCGFJ_01098	1.07e-300	-	-	-	E	-	-	-	SAF
HHOLCGFJ_01099	1.9e-89	-	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HHOLCGFJ_01100	8.78e-115	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HHOLCGFJ_01101	7.47e-235	-	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol sorbitol-specific transporter subunit IIB
HHOLCGFJ_01102	6.36e-78	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HHOLCGFJ_01103	2.66e-220	-	-	-	K	-	-	-	Putative sugar-binding domain
HHOLCGFJ_01104	2.33e-206	-	-	-	S	-	-	-	CAAX amino terminal protease family protein
HHOLCGFJ_01105	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HHOLCGFJ_01107	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HHOLCGFJ_01108	6.61e-183	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_01109	3.93e-248	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HHOLCGFJ_01110	3.63e-172	yvcP	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_01111	1.07e-65	-	-	-	-	-	-	-	-
HHOLCGFJ_01112	8.9e-216	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HHOLCGFJ_01113	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HHOLCGFJ_01114	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HHOLCGFJ_01115	9.24e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HHOLCGFJ_01116	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HHOLCGFJ_01117	7.28e-288	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHOLCGFJ_01118	4.63e-175	lacR	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
HHOLCGFJ_01119	0.0	ltaS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HHOLCGFJ_01120	1.41e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHOLCGFJ_01121	2.46e-310	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HHOLCGFJ_01122	2.52e-206	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_01123	1.57e-201	-	-	-	P	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHOLCGFJ_01124	2.08e-81	-	-	-	FJ	-	-	-	tRNA wobble adenosine to inosine editing
HHOLCGFJ_01125	5.51e-19	-	-	-	S	-	-	-	Inner spore coat protein D
HHOLCGFJ_01126	0.0	M1-554	-	-	G	-	-	-	Endonuclease Exonuclease Phosphatase
HHOLCGFJ_01127	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
HHOLCGFJ_01128	7.35e-249	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHOLCGFJ_01129	1.16e-169	potC3	-	-	P	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_01130	1.26e-178	-	-	-	E	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1176 ABC-type spermidine putrescine transport system, permease component I
HHOLCGFJ_01131	7.4e-226	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HHOLCGFJ_01132	8.98e-253	-	-	-	E	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0687 Spermidine putrescine-binding periplasmic protein
HHOLCGFJ_01133	1.49e-74	-	-	-	-	-	-	-	-
HHOLCGFJ_01134	2.59e-69	-	-	-	-	-	-	-	-
HHOLCGFJ_01136	1.31e-212	XK27_03180	-	-	T	-	-	-	Belongs to the universal stress protein A family
HHOLCGFJ_01137	6.56e-182	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HHOLCGFJ_01138	3.94e-221	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HHOLCGFJ_01139	0.0	fruC	2.7.1.202	-	G	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HHOLCGFJ_01140	9.17e-100	fruD	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHOLCGFJ_01141	3.57e-202	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
HHOLCGFJ_01142	2.94e-112	-	-	-	-	-	-	-	-
HHOLCGFJ_01143	1.04e-110	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
HHOLCGFJ_01146	1.26e-10	tlp	-	-	S	ko:K06434	-	ko00000	spore protein
HHOLCGFJ_01147	7.56e-209	-	-	-	K	-	-	-	LysR substrate binding domain
HHOLCGFJ_01148	9.01e-137	ywqN_1	-	-	S	-	-	-	NAD(P)H-dependent
HHOLCGFJ_01149	5.4e-152	ycfA	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_01150	7.01e-252	ybhR	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HHOLCGFJ_01151	9.79e-184	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HHOLCGFJ_01152	3.98e-110	-	-	-	M	ko:K01993	-	ko00000	PFAM secretion protein HlyD family protein
HHOLCGFJ_01153	2.37e-271	thrCA	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HHOLCGFJ_01154	5.49e-193	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HHOLCGFJ_01155	5.38e-309	-	-	-	KT	-	-	-	transcriptional regulatory protein
HHOLCGFJ_01156	0.0	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
HHOLCGFJ_01157	0.0	-	-	-	H	ko:K12942	-	ko00000	AbgT putative transporter family
HHOLCGFJ_01158	3.13e-314	-	-	-	S	ko:K12940	-	ko00000,ko01002	Peptidase dimerisation domain
HHOLCGFJ_01159	8.99e-42	-	-	-	C	-	-	-	4Fe-4S binding domain
HHOLCGFJ_01160	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1450)
HHOLCGFJ_01161	6.2e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, C-terminal domain
HHOLCGFJ_01162	9.45e-152	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_01163	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HHOLCGFJ_01164	2.62e-197	-	-	-	S	-	-	-	Glycosyl transferase family 2
HHOLCGFJ_01165	2.31e-258	-	-	-	M	-	-	-	Glycosyl transferases group 1
HHOLCGFJ_01166	8.35e-73	-	-	-	-	-	-	-	-
HHOLCGFJ_01167	8.96e-317	-	-	-	M	-	-	-	-O-antigen
HHOLCGFJ_01168	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHOLCGFJ_01169	2.96e-91	-	-	-	-	-	-	-	-
HHOLCGFJ_01170	6.65e-183	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HHOLCGFJ_01171	3.13e-236	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HHOLCGFJ_01172	8.63e-226	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HHOLCGFJ_01178	4.37e-207	-	-	-	UW	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
HHOLCGFJ_01190	1.1e-53	-	-	-	-	-	-	-	-
HHOLCGFJ_01191	1.98e-123	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHOLCGFJ_01192	9.05e-144	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HHOLCGFJ_01193	5.77e-144	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HHOLCGFJ_01194	2e-63	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HHOLCGFJ_01195	5.16e-272	-	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HHOLCGFJ_01196	1.74e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHOLCGFJ_01197	3.58e-198	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HHOLCGFJ_01198	2.65e-118	dinB	-	-	S	-	-	-	DinB family
HHOLCGFJ_01199	8.87e-215	yobV	-	-	K	-	-	-	WYL domain
HHOLCGFJ_01200	2.57e-133	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HHOLCGFJ_01201	1.28e-165	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHOLCGFJ_01202	3.46e-242	-	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHOLCGFJ_01204	6.37e-152	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHOLCGFJ_01205	1.8e-270	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_01206	1.59e-53	-	-	-	-	-	-	-	-
HHOLCGFJ_01207	6.92e-193	yrzF	-	-	KLT	-	-	-	serine threonine protein kinase
HHOLCGFJ_01208	2.08e-112	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_01209	9.84e-181	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HHOLCGFJ_01210	1.39e-142	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HHOLCGFJ_01212	3.25e-185	-	-	-	-	-	-	-	-
HHOLCGFJ_01213	8.03e-160	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_01214	7.5e-83	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HHOLCGFJ_01216	5.47e-173	-	-	-	-	-	-	-	-
HHOLCGFJ_01217	1.85e-204	-	-	-	S	-	-	-	NYN domain
HHOLCGFJ_01218	2.51e-69	-	-	-	K	-	-	-	sequence-specific DNA binding
HHOLCGFJ_01219	0.0	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HHOLCGFJ_01220	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_01221	1.07e-209	-	-	-	G	ko:K02025,ko:K17238	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_01222	1.77e-203	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_01223	7.22e-262	-	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHOLCGFJ_01224	2.18e-148	-	-	-	-	-	-	-	-
HHOLCGFJ_01226	3.43e-236	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HHOLCGFJ_01228	2.37e-224	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HHOLCGFJ_01229	4.03e-207	lplC7	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HHOLCGFJ_01230	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_01231	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	invertase
HHOLCGFJ_01232	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HHOLCGFJ_01233	4.11e-173	fabG9	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HHOLCGFJ_01234	9.52e-285	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HHOLCGFJ_01235	2.24e-37	-	-	-	-	-	-	-	-
HHOLCGFJ_01236	1.82e-130	pncA	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HHOLCGFJ_01237	8.45e-147	ymaB	-	-	S	-	-	-	MutT family
HHOLCGFJ_01238	1.08e-246	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHOLCGFJ_01239	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHOLCGFJ_01240	2.08e-85	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HHOLCGFJ_01241	2.39e-179	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HHOLCGFJ_01242	2.9e-255	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HHOLCGFJ_01243	0.0	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HHOLCGFJ_01244	4.63e-299	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HHOLCGFJ_01245	1.68e-176	-	-	-	I	-	-	-	CDP-alcohol phosphatidyltransferase
HHOLCGFJ_01246	7.06e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HHOLCGFJ_01247	0.0	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHOLCGFJ_01248	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HHOLCGFJ_01249	1.2e-207	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HHOLCGFJ_01250	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHOLCGFJ_01251	3.47e-267	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	alcohol dehydrogenase
HHOLCGFJ_01252	7.96e-19	-	-	-	-	-	-	-	-
HHOLCGFJ_01253	0.0	cckA	2.7.13.3	-	T	ko:K02482	-	ko00000,ko01000,ko01001,ko02022	GAF domain
HHOLCGFJ_01254	0.0	-	-	-	T	ko:K02481	-	ko00000,ko02022	Sigma-54 interaction domain
HHOLCGFJ_01255	1.5e-256	adhA	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HHOLCGFJ_01256	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HHOLCGFJ_01257	2.83e-236	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HHOLCGFJ_01259	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HHOLCGFJ_01260	2.23e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHOLCGFJ_01261	1.19e-71	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_01262	2.59e-234	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HHOLCGFJ_01263	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HHOLCGFJ_01264	2.97e-60	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HHOLCGFJ_01265	1.14e-175	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HHOLCGFJ_01266	1.29e-58	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HHOLCGFJ_01267	4.19e-205	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHOLCGFJ_01268	3.04e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HHOLCGFJ_01269	3.01e-225	-	-	-	S	-	-	-	NurA
HHOLCGFJ_01270	0.0	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
HHOLCGFJ_01271	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHOLCGFJ_01272	1.2e-106	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HHOLCGFJ_01273	2.35e-237	pelB	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Amb_all
HHOLCGFJ_01275	0.0	-	-	-	S	-	-	-	ABC transporter
HHOLCGFJ_01276	1.34e-152	-	-	-	T	-	-	-	protein histidine kinase activity
HHOLCGFJ_01277	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HHOLCGFJ_01278	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HHOLCGFJ_01279	2.23e-285	yabE	-	-	T	-	-	-	protein conserved in bacteria
HHOLCGFJ_01280	9.52e-149	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHOLCGFJ_01281	4.15e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHOLCGFJ_01282	4.38e-209	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HHOLCGFJ_01283	4.02e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_01284	1.8e-34	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HHOLCGFJ_01285	2.35e-211	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HHOLCGFJ_01286	2.69e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HHOLCGFJ_01287	1.42e-81	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HHOLCGFJ_01288	2.26e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HHOLCGFJ_01289	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHOLCGFJ_01290	6.02e-219	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHOLCGFJ_01291	1.95e-141	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HHOLCGFJ_01292	7.69e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHOLCGFJ_01293	7.35e-53	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HHOLCGFJ_01294	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHOLCGFJ_01295	2.3e-123	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HHOLCGFJ_01296	1.66e-136	-	-	-	S	-	-	-	Yip1 domain
HHOLCGFJ_01297	3.02e-254	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHOLCGFJ_01298	9.82e-116	-	-	-	S	-	-	-	Yip1 domain
HHOLCGFJ_01299	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHOLCGFJ_01300	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HHOLCGFJ_01301	2.69e-43	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HHOLCGFJ_01302	1.39e-151	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HHOLCGFJ_01303	3.01e-226	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLCGFJ_01304	4.58e-114	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHOLCGFJ_01305	8.27e-255	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HHOLCGFJ_01306	9.86e-135	-	-	-	S	-	-	-	SNARE associated Golgi protein
HHOLCGFJ_01307	6.77e-71	yabP	-	-	S	-	-	-	Sporulation protein YabP
HHOLCGFJ_01308	1.33e-94	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HHOLCGFJ_01309	1.73e-80	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HHOLCGFJ_01310	7.4e-93	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HHOLCGFJ_01312	2.07e-284	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
HHOLCGFJ_01313	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HHOLCGFJ_01314	2.67e-166	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HHOLCGFJ_01315	5.96e-226	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HHOLCGFJ_01316	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHOLCGFJ_01317	2.21e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HHOLCGFJ_01318	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHOLCGFJ_01319	3.69e-183	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HHOLCGFJ_01320	3.73e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHOLCGFJ_01321	3.24e-221	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HHOLCGFJ_01322	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHOLCGFJ_01323	2.26e-141	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HHOLCGFJ_01324	1.84e-199	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HHOLCGFJ_01325	1.23e-190	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HHOLCGFJ_01326	1.81e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHOLCGFJ_01327	1.3e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHOLCGFJ_01328	1.86e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHOLCGFJ_01329	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HHOLCGFJ_01330	4.79e-95	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HHOLCGFJ_01331	4.37e-124	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HHOLCGFJ_01332	6.55e-251	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HHOLCGFJ_01333	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HHOLCGFJ_01334	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHOLCGFJ_01335	4.09e-249	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HHOLCGFJ_01336	1.18e-253	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HHOLCGFJ_01337	1.67e-152	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HHOLCGFJ_01338	1.09e-109	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HHOLCGFJ_01339	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHOLCGFJ_01340	9.81e-157	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HHOLCGFJ_01341	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HHOLCGFJ_01342	1.04e-91	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHOLCGFJ_01343	2.3e-185	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHOLCGFJ_01344	8.14e-115	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HHOLCGFJ_01345	4.15e-153	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HHOLCGFJ_01346	2.37e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHOLCGFJ_01347	1.83e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HHOLCGFJ_01348	1.19e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHOLCGFJ_01349	4.64e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHOLCGFJ_01350	8.48e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHOLCGFJ_01351	1.27e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHOLCGFJ_01352	1.45e-157	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HHOLCGFJ_01353	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHOLCGFJ_01354	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHOLCGFJ_01355	1.84e-47	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HHOLCGFJ_01356	4.33e-95	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHOLCGFJ_01357	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHOLCGFJ_01358	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHOLCGFJ_01359	7.02e-288	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHOLCGFJ_01360	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HHOLCGFJ_01361	9.49e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHOLCGFJ_01362	5.45e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HHOLCGFJ_01363	9.74e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHOLCGFJ_01364	3.58e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHOLCGFJ_01365	2.63e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHOLCGFJ_01366	8.5e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHOLCGFJ_01367	1.76e-154	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHOLCGFJ_01368	3.79e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHOLCGFJ_01369	5.12e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HHOLCGFJ_01370	2.17e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHOLCGFJ_01371	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHOLCGFJ_01372	7.7e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHOLCGFJ_01373	2.21e-121	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHOLCGFJ_01374	2.66e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHOLCGFJ_01375	6.37e-125	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHOLCGFJ_01376	8.96e-79	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHOLCGFJ_01377	1.59e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHOLCGFJ_01378	7.06e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HHOLCGFJ_01379	9.26e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HHOLCGFJ_01380	4.17e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHOLCGFJ_01381	8.08e-154	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHOLCGFJ_01382	9.44e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HHOLCGFJ_01383	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHOLCGFJ_01384	5.99e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HHOLCGFJ_01385	8.92e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHOLCGFJ_01386	4.05e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHOLCGFJ_01387	4.06e-216	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHOLCGFJ_01388	3.65e-78	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HHOLCGFJ_01389	8.83e-208	cbiO	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHOLCGFJ_01390	9.07e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHOLCGFJ_01391	1.66e-174	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHOLCGFJ_01392	4.33e-189	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHOLCGFJ_01393	2.77e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHOLCGFJ_01394	4.45e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HHOLCGFJ_01395	1.32e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HHOLCGFJ_01396	1.08e-41	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_01399	3.13e-159	yhjR	-	-	S	-	-	-	Rubrerythrin
HHOLCGFJ_01400	3.93e-19	-	-	-	-	-	-	-	-
HHOLCGFJ_01403	3.65e-105	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HHOLCGFJ_01404	9.03e-173	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HHOLCGFJ_01405	1.02e-196	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HHOLCGFJ_01406	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_01407	1.67e-249	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HHOLCGFJ_01408	2.04e-28	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_01409	1.34e-95	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HHOLCGFJ_01410	1.67e-40	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PFAM Phosphotransferase system, lactose cellobiose-specific IIB subunit
HHOLCGFJ_01411	8.66e-223	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHOLCGFJ_01412	3.88e-91	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HHOLCGFJ_01413	1.4e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF4127)
HHOLCGFJ_01414	3.18e-119	-	-	-	K	-	-	-	transcriptional regulator, RpiR family
HHOLCGFJ_01415	6.68e-96	gerD	-	-	S	ko:K06294	-	ko00000	Spore gernimation protein
HHOLCGFJ_01416	8e-130	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HHOLCGFJ_01417	6.89e-182	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HHOLCGFJ_01418	5.74e-46	-	-	-	-	-	-	-	-
HHOLCGFJ_01420	8.93e-193	yaaC	-	-	S	-	-	-	YaaC-like Protein
HHOLCGFJ_01421	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HHOLCGFJ_01422	9.77e-306	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHOLCGFJ_01423	3.3e-282	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHOLCGFJ_01424	5.15e-192	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHOLCGFJ_01425	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HHOLCGFJ_01426	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HHOLCGFJ_01427	4.15e-300	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HHOLCGFJ_01428	5.97e-07	gudB	1.4.1.2, 1.4.1.4	-	E	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HHOLCGFJ_01429	0.0	nhaC_2	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HHOLCGFJ_01431	1.28e-299	-	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HHOLCGFJ_01432	8.27e-293	-	2.5.1.48, 4.4.1.11	-	E	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HHOLCGFJ_01433	5.57e-290	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
HHOLCGFJ_01434	2.28e-248	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HHOLCGFJ_01435	0.0	gabD_2	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHOLCGFJ_01436	1.73e-81	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HHOLCGFJ_01437	8.69e-187	glnH	-	-	ET	ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Ligated ion channel L-glutamate- and glycine-binding site
HHOLCGFJ_01438	1.23e-141	glnP	-	-	E	ko:K02029,ko:K10037,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Polar amino acid ABC transporter, inner membrane subunit
HHOLCGFJ_01439	3.01e-165	-	3.6.3.21	-	E	ko:K02028,ko:K10038	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HHOLCGFJ_01440	4.05e-244	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_01441	4.75e-247	-	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_01442	3.19e-214	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_01443	3.86e-205	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_01444	0.0	gsiB_3	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HHOLCGFJ_01445	7.09e-69	-	-	-	-	-	-	-	-
HHOLCGFJ_01448	5.14e-111	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHOLCGFJ_01449	1.48e-135	clpP1	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHOLCGFJ_01450	1.06e-150	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HHOLCGFJ_01451	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHOLCGFJ_01452	4.53e-51	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHOLCGFJ_01453	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHOLCGFJ_01454	6.78e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HHOLCGFJ_01455	2.37e-27	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HHOLCGFJ_01458	3.49e-25	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_01460	1.82e-70	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
HHOLCGFJ_01461	2.89e-114	-	-	-	D	-	-	-	Fic/DOC family
HHOLCGFJ_01464	4.29e-55	nucH	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	COG1525 Micrococcal nuclease (thermonuclease) homologs
HHOLCGFJ_01469	0.0	topB	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase III
HHOLCGFJ_01474	4.41e-100	-	-	-	L	-	-	-	Resolvase, N terminal domain
HHOLCGFJ_01475	1.44e-05	-	-	-	K	ko:K19156	-	ko00000,ko02048	AbrB family transcriptional regulator
HHOLCGFJ_01477	6.13e-43	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HHOLCGFJ_01478	3.77e-99	-	-	-	-	-	-	-	-
HHOLCGFJ_01484	7.32e-44	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHOLCGFJ_01486	1.17e-16	-	-	-	S	-	-	-	PrgI family protein
HHOLCGFJ_01487	1.65e-271	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
HHOLCGFJ_01488	2.48e-57	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Peptidase family M23
HHOLCGFJ_01490	1.7e-08	-	-	-	S	-	-	-	Domain of unknown function (DUF4366)
HHOLCGFJ_01493	1.43e-30	-	-	-	S	-	-	-	Maff2 family
HHOLCGFJ_01494	1.3e-197	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
HHOLCGFJ_01495	9.42e-82	-	-	-	-	-	-	-	-
HHOLCGFJ_01497	1.57e-26	-	-	-	-	-	-	-	-
HHOLCGFJ_01498	6.55e-65	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
HHOLCGFJ_01530	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HHOLCGFJ_01531	6.22e-107	-	-	-	L	-	-	-	Transposase IS200 like
HHOLCGFJ_01533	6.43e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HHOLCGFJ_01534	1.6e-63	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HHOLCGFJ_01535	3.32e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HHOLCGFJ_01536	2.63e-256	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HHOLCGFJ_01537	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HHOLCGFJ_01538	5.57e-86	-	-	-	J	-	-	-	oxidation-reduction process
HHOLCGFJ_01539	1.68e-108	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HHOLCGFJ_01540	1.85e-220	-	-	-	S	-	-	-	thiolester hydrolase activity
HHOLCGFJ_01541	9.23e-292	-	3.3.2.9	-	S	ko:K01253	ko00980,ko04976,ko05204,map00980,map04976,map05204	ko00000,ko00001,ko01000,ko01002	Epoxide hydrolase N terminus
HHOLCGFJ_01542	2.55e-13	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHOLCGFJ_01543	0.0	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HHOLCGFJ_01544	1.12e-142	-	-	-	K	-	-	-	Bacterial transcriptional repressor C-terminal
HHOLCGFJ_01545	2.35e-101	nsrR3	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_01546	0.0	ypfE	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
HHOLCGFJ_01547	8.95e-90	-	-	-	-	-	-	-	-
HHOLCGFJ_01548	3.05e-121	-	-	-	F	-	-	-	uridine kinase
HHOLCGFJ_01549	3.79e-181	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHOLCGFJ_01550	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
HHOLCGFJ_01551	8.96e-59	ykvN	-	-	K	-	-	-	HxlR-like helix-turn-helix
HHOLCGFJ_01552	2.07e-43	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HHOLCGFJ_01553	2.06e-259	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HHOLCGFJ_01554	1.68e-131	-	-	-	S	-	-	-	Domain of unknown function (DUF4297)
HHOLCGFJ_01556	1.62e-157	-	-	-	L	-	-	-	AAA domain
HHOLCGFJ_01557	2.64e-210	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_01558	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HHOLCGFJ_01559	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HHOLCGFJ_01560	6.12e-278	-	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	amidohydrolase
HHOLCGFJ_01561	1.88e-67	-	-	-	S	-	-	-	PRD domain
HHOLCGFJ_01562	9.35e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
HHOLCGFJ_01563	6.36e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
HHOLCGFJ_01564	9.36e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
HHOLCGFJ_01565	8.24e-146	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
HHOLCGFJ_01566	8.41e-260	selA	2.9.1.1	-	E	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HHOLCGFJ_01567	9.27e-159	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HHOLCGFJ_01568	0.000685	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HHOLCGFJ_01569	2.5e-233	pld1	1.1.1.122	-	C	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Aldo/keto reductase family
HHOLCGFJ_01570	2.4e-120	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HHOLCGFJ_01571	1.41e-173	-	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HHOLCGFJ_01572	8.9e-137	-	-	-	K	-	-	-	TetR family transcriptional regulator
HHOLCGFJ_01573	1e-271	-	-	-	CH	-	-	-	FAD binding domain
HHOLCGFJ_01574	1.27e-275	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HHOLCGFJ_01575	3.92e-142	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HHOLCGFJ_01576	1.58e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HHOLCGFJ_01577	9.86e-145	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHOLCGFJ_01578	1.49e-222	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
HHOLCGFJ_01579	4.23e-76	ydzF	-	-	K	-	-	-	HxlR-like helix-turn-helix
HHOLCGFJ_01580	2.54e-80	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_01581	2.92e-75	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_01582	1.91e-37	rmeD	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HHOLCGFJ_01583	1.48e-112	-	-	-	C	-	-	-	aldo keto reductase
HHOLCGFJ_01584	2.09e-62	-	-	-	K	-	-	-	MarR family
HHOLCGFJ_01585	9.72e-127	-	-	-	EP	ko:K15585	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_01586	1.21e-135	nikC	-	-	P	ko:K02034,ko:K15586	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	With NikABDE is involved in nickel transport into the cell
HHOLCGFJ_01587	1.47e-112	nikD	3.6.3.24	-	EP	ko:K02031,ko:K15587	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	ABC-type dipeptide oligopeptide nickel transport system, ATPase component
HHOLCGFJ_01588	1.8e-121	nikE	3.6.3.24	-	E	ko:K02031,ko:K02032,ko:K10824	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HHOLCGFJ_01589	3.36e-265	nikA	-	-	E	ko:K15584	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLCGFJ_01590	2.67e-286	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HHOLCGFJ_01591	3.37e-292	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HHOLCGFJ_01592	5.42e-279	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HHOLCGFJ_01593	3.77e-272	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_01595	6.29e-75	serS3	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHOLCGFJ_01596	5.07e-06	serS3	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHOLCGFJ_01597	3.29e-170	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HHOLCGFJ_01598	4.63e-142	-	-	-	L	-	-	-	DNA alkylation repair enzyme
HHOLCGFJ_01600	2.24e-102	-	-	-	K	-	-	-	Helix-turn-helix domain
HHOLCGFJ_01601	1.45e-186	-	-	-	S	-	-	-	Alpha beta hydrolase
HHOLCGFJ_01602	6.36e-98	yfiK	-	-	K	-	-	-	Regulator
HHOLCGFJ_01603	1.17e-94	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_01604	3.85e-143	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_01605	6.08e-107	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HHOLCGFJ_01606	2.81e-117	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system, permease component
HHOLCGFJ_01607	9.23e-111	-	-	-	S	-	-	-	Chlorophyllase
HHOLCGFJ_01608	1.68e-132	-	-	-	S	-	-	-	Chlorophyllase
HHOLCGFJ_01610	7.32e-51	-	-	-	K	-	-	-	Helix-turn-helix domain
HHOLCGFJ_01611	0.000136	pepF1_3	-	-	E	-	-	-	oligoendopeptidase F
HHOLCGFJ_01612	3.82e-146	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_01613	1.67e-167	-	-	-	GM	-	-	-	NmrA-like family
HHOLCGFJ_01614	2.79e-07	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
HHOLCGFJ_01615	1.28e-138	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
HHOLCGFJ_01616	4.53e-147	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HHOLCGFJ_01617	1.01e-218	tnpA1	-	-	L	-	-	-	Transposase
HHOLCGFJ_01618	2.19e-172	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_01619	5.06e-298	serS3	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHOLCGFJ_01620	3.67e-164	-	-	-	L	-	-	-	DNA alkylation repair enzyme
HHOLCGFJ_01621	6.35e-145	-	-	-	S	-	-	-	AAA domain
HHOLCGFJ_01622	4.67e-119	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HHOLCGFJ_01623	2.43e-246	-	-	-	T	-	-	-	Signal transduction histidine kinase
HHOLCGFJ_01624	1.14e-136	-	-	-	KT	-	-	-	LuxR family transcriptional regulator
HHOLCGFJ_01625	6.26e-218	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HHOLCGFJ_01626	1.16e-271	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HHOLCGFJ_01627	7.54e-244	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HHOLCGFJ_01628	8.09e-196	gspA	-	-	M	-	-	-	Glycosyl transferase family 8
HHOLCGFJ_01629	1.08e-83	yxjI	-	-	S	-	-	-	LURP-one-related
HHOLCGFJ_01630	1.08e-188	adcA	-	-	P	ko:K09815,ko:K09818	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HHOLCGFJ_01631	4.44e-160	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HHOLCGFJ_01632	5.26e-123	p20	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HHOLCGFJ_01633	3.13e-62	-	-	-	-	-	-	-	-
HHOLCGFJ_01634	1.51e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHOLCGFJ_01635	0.0	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HHOLCGFJ_01636	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K06931,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HHOLCGFJ_01637	8.39e-75	-	-	-	S	-	-	-	Regulatory protein YrvL
HHOLCGFJ_01638	2.25e-241	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HHOLCGFJ_01639	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Sodium:sulfate symporter transmembrane region
HHOLCGFJ_01640	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HHOLCGFJ_01641	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HHOLCGFJ_01642	2.45e-124	-	-	-	-	-	-	-	-
HHOLCGFJ_01643	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHOLCGFJ_01644	1.25e-137	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHOLCGFJ_01645	1.89e-63	-	-	-	H	-	-	-	3-demethylubiquinone-9 3-O-methyltransferase activity
HHOLCGFJ_01646	1.01e-127	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide
HHOLCGFJ_01648	2.64e-268	pamO	-	-	P	ko:K07222	-	ko00000	Flavin-binding monooxygenase-like
HHOLCGFJ_01649	0.0	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_01650	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HHOLCGFJ_01651	3.15e-195	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHOLCGFJ_01652	7.57e-119	-	-	-	S	-	-	-	MepB protein
HHOLCGFJ_01653	2.75e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_01654	8.23e-169	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HHOLCGFJ_01655	1.55e-81	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_01656	3.38e-158	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HHOLCGFJ_01657	1.17e-166	-	-	-	-	-	-	-	-
HHOLCGFJ_01658	1.61e-251	yhfE	-	-	G	-	-	-	peptidase M42
HHOLCGFJ_01659	6.41e-106	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HHOLCGFJ_01660	2.29e-130	yhzB	-	-	S	-	-	-	B3/4 domain
HHOLCGFJ_01661	5.48e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HHOLCGFJ_01662	2.32e-121	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHOLCGFJ_01663	4.7e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_01664	1.66e-215	yhbB	-	-	S	-	-	-	Putative amidase domain
HHOLCGFJ_01665	1.24e-114	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHOLCGFJ_01666	3.08e-115	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HHOLCGFJ_01667	1.17e-71	-	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HHOLCGFJ_01668	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HHOLCGFJ_01669	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HHOLCGFJ_01670	2.19e-135	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HHOLCGFJ_01671	1.69e-179	cysA1	-	-	S	-	-	-	AAA domain
HHOLCGFJ_01672	1.11e-281	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HHOLCGFJ_01674	1.8e-213	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_01675	0.0	-	-	-	EGP	-	-	-	the major facilitator superfamily
HHOLCGFJ_01676	1.18e-226	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HHOLCGFJ_01677	3.14e-191	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HHOLCGFJ_01679	7.16e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF664)
HHOLCGFJ_01680	0.0	-	-	-	G	ko:K10297	-	ko00000,ko04121	Right handed beta helix region
HHOLCGFJ_01681	3.19e-205	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_01682	0.0	-	-	-	E	ko:K03307	-	ko00000	Sodium:solute symporter family
HHOLCGFJ_01683	3.83e-165	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HHOLCGFJ_01684	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HHOLCGFJ_01685	1.33e-168	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HHOLCGFJ_01686	2.95e-284	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHOLCGFJ_01687	6.62e-177	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHOLCGFJ_01688	1.34e-168	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HHOLCGFJ_01689	1.92e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HHOLCGFJ_01690	8.12e-151	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HHOLCGFJ_01691	2.31e-175	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HHOLCGFJ_01692	1.02e-93	-	-	-	-	-	-	-	-
HHOLCGFJ_01694	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHOLCGFJ_01695	7.42e-162	sfsA	-	-	S	ko:K06206	-	ko00000	Sugar fermentation stimulation protein
HHOLCGFJ_01696	0.0	-	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HHOLCGFJ_01697	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HHOLCGFJ_01698	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HHOLCGFJ_01699	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HHOLCGFJ_01700	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HHOLCGFJ_01701	2.59e-295	avtA	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHOLCGFJ_01702	4.1e-193	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
HHOLCGFJ_01703	3.52e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HHOLCGFJ_01704	1.97e-275	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HHOLCGFJ_01705	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HHOLCGFJ_01706	1.95e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HHOLCGFJ_01707	1.03e-172	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HHOLCGFJ_01708	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HHOLCGFJ_01710	1.76e-277	-	-	-	-	-	-	-	-
HHOLCGFJ_01711	1.78e-102	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HHOLCGFJ_01712	8.44e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_01713	2.85e-207	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HHOLCGFJ_01714	2.94e-31	-	-	-	-	-	-	-	-
HHOLCGFJ_01716	8.19e-267	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HHOLCGFJ_01717	2.8e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HHOLCGFJ_01718	1.44e-201	yhaX	-	-	S	-	-	-	hydrolases of the HAD superfamily
HHOLCGFJ_01720	1.47e-66	-	-	-	-	-	-	-	-
HHOLCGFJ_01721	2.31e-162	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_01722	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_01723	4.85e-231	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HHOLCGFJ_01724	6.88e-59	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HHOLCGFJ_01725	2.1e-213	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHOLCGFJ_01726	2.48e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HHOLCGFJ_01727	1.99e-139	-	-	-	S	-	-	-	Protein conserved in bacteria
HHOLCGFJ_01728	2.03e-141	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HHOLCGFJ_01729	1.39e-72	yhaH	-	-	D	-	-	-	gas vesicle protein
HHOLCGFJ_01730	3.09e-268	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HHOLCGFJ_01731	1.56e-98	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HHOLCGFJ_01732	8.06e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HHOLCGFJ_01733	2.55e-287	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HHOLCGFJ_01734	6.61e-167	ecsC	-	-	S	-	-	-	EcsC protein family
HHOLCGFJ_01735	1.59e-156	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HHOLCGFJ_01736	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HHOLCGFJ_01737	5.06e-260	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HHOLCGFJ_01738	2.93e-233	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HHOLCGFJ_01739	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HHOLCGFJ_01741	4.46e-132	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HHOLCGFJ_01742	5.26e-297	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHOLCGFJ_01743	3.91e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HHOLCGFJ_01744	9.54e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HHOLCGFJ_01745	8.22e-117	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HHOLCGFJ_01746	7.27e-266	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HHOLCGFJ_01747	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HHOLCGFJ_01748	2.05e-193	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HHOLCGFJ_01749	4.39e-268	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HHOLCGFJ_01750	3.95e-273	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HHOLCGFJ_01751	7.43e-25	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHOLCGFJ_01752	6.71e-85	-	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	cytochrome c oxidase subunit II
HHOLCGFJ_01753	5.29e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HHOLCGFJ_01754	1.41e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHOLCGFJ_01755	2.23e-234	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHOLCGFJ_01756	7.27e-38	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HHOLCGFJ_01757	3.35e-245	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHOLCGFJ_01758	6.48e-291	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HHOLCGFJ_01759	1.92e-51	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HHOLCGFJ_01760	2.94e-80	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HHOLCGFJ_01761	1.1e-102	-	-	-	S	-	-	-	membrane
HHOLCGFJ_01762	5.21e-41	yodI	-	-	-	-	-	-	-
HHOLCGFJ_01763	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHOLCGFJ_01764	2.15e-29	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HHOLCGFJ_01765	5.23e-295	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHOLCGFJ_01766	2.96e-196	secF	-	-	U	ko:K03074,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHOLCGFJ_01767	7.21e-53	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HHOLCGFJ_01768	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HHOLCGFJ_01769	4.03e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHOLCGFJ_01770	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHOLCGFJ_01771	5.58e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHOLCGFJ_01772	9.88e-239	-	-	-	K	-	-	-	LacI family transcriptional regulator
HHOLCGFJ_01773	9.13e-185	thuA	-	-	G	-	-	-	Trehalose utilisation
HHOLCGFJ_01774	2.36e-247	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_01775	2.91e-280	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HHOLCGFJ_01777	3.51e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HHOLCGFJ_01778	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HHOLCGFJ_01779	1.07e-282	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HHOLCGFJ_01780	5.89e-66	-	-	-	-	-	-	-	-
HHOLCGFJ_01781	1.05e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HHOLCGFJ_01782	9.67e-174	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HHOLCGFJ_01783	3.15e-138	rsfA	-	-	S	ko:K06314	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_01784	8.06e-297	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HHOLCGFJ_01785	2.93e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_01786	3.39e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HHOLCGFJ_01787	4.26e-275	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHOLCGFJ_01788	1.7e-65	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HHOLCGFJ_01789	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHOLCGFJ_01790	4.85e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_01791	1.11e-41	yrzR	-	-	-	-	-	-	-
HHOLCGFJ_01792	8.75e-240	yrrI	-	-	S	-	-	-	AI-2E family transporter
HHOLCGFJ_01793	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHOLCGFJ_01794	6.53e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HHOLCGFJ_01795	2.3e-96	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHOLCGFJ_01796	1.23e-44	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HHOLCGFJ_01797	2.1e-269	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHOLCGFJ_01798	9.8e-150	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HHOLCGFJ_01799	5.68e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HHOLCGFJ_01800	8.99e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHOLCGFJ_01801	6.64e-17	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HHOLCGFJ_01802	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HHOLCGFJ_01803	7.14e-192	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HHOLCGFJ_01804	8.69e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHOLCGFJ_01806	7.57e-103	-	-	-	-	-	-	-	-
HHOLCGFJ_01807	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HHOLCGFJ_01808	4.13e-190	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HHOLCGFJ_01809	4.46e-185	-	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HHOLCGFJ_01810	1.29e-204	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HHOLCGFJ_01811	3.49e-196	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_01812	4.19e-140	arpR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_01813	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Starch/carbohydrate-binding module (family 53)
HHOLCGFJ_01814	6.21e-147	XK27_06885	-	-	L	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HHOLCGFJ_01815	3.46e-241	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HHOLCGFJ_01816	0.0	-	-	-	S	-	-	-	Membrane
HHOLCGFJ_01817	2.43e-285	hipO3	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
HHOLCGFJ_01818	1.3e-215	ybaS	-	-	S	-	-	-	Na -dependent transporter
HHOLCGFJ_01819	1.27e-159	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHOLCGFJ_01820	2.71e-35	-	-	-	-	-	-	-	-
HHOLCGFJ_01822	8.1e-71	-	-	-	-	-	-	-	-
HHOLCGFJ_01823	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HHOLCGFJ_01824	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HHOLCGFJ_01825	6.17e-73	nirD	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HHOLCGFJ_01826	0.0	nirB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HHOLCGFJ_01827	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHOLCGFJ_01828	7.82e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HHOLCGFJ_01829	0.0	-	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HHOLCGFJ_01831	3.05e-196	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7	-	H	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HHOLCGFJ_01832	5.78e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHOLCGFJ_01833	1.19e-88	-	-	-	P	ko:K05571	-	ko00000,ko02000	Na+/H+ antiporter subunit
HHOLCGFJ_01834	4.41e-52	-	-	-	P	ko:K05570	-	ko00000,ko02000	Multiple resistance and pH regulation protein F (MrpF / PhaF)
HHOLCGFJ_01835	1.54e-106	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHOLCGFJ_01836	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHOLCGFJ_01837	1.13e-66	mnhC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHOLCGFJ_01838	1.09e-95	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHOLCGFJ_01839	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HHOLCGFJ_01841	1.52e-125	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HHOLCGFJ_01842	2.78e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HHOLCGFJ_01843	1.51e-196	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HHOLCGFJ_01844	2.17e-62	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HHOLCGFJ_01845	4.97e-138	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHOLCGFJ_01846	4.96e-139	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HHOLCGFJ_01847	5.25e-81	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHOLCGFJ_01848	5.98e-208	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HHOLCGFJ_01849	1.15e-181	-	-	-	S	-	-	-	Methyltransferase domain
HHOLCGFJ_01850	4.13e-190	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHOLCGFJ_01851	6.16e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HHOLCGFJ_01852	5.15e-142	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HHOLCGFJ_01853	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HHOLCGFJ_01854	9.62e-09	-	-	-	S	-	-	-	YqzM-like protein
HHOLCGFJ_01855	4.29e-231	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HHOLCGFJ_01856	1.15e-48	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HHOLCGFJ_01857	1.77e-262	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHOLCGFJ_01858	6.75e-268	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HHOLCGFJ_01859	8.8e-70	-	-	-	-	-	-	-	-
HHOLCGFJ_01860	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHOLCGFJ_01861	1.15e-282	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HHOLCGFJ_01862	7.24e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHOLCGFJ_01863	3.52e-113	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHOLCGFJ_01864	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HHOLCGFJ_01865	2.02e-268	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHOLCGFJ_01866	1.49e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HHOLCGFJ_01867	5.19e-170	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHOLCGFJ_01868	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HHOLCGFJ_01869	1.14e-176	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HHOLCGFJ_01870	2.51e-280	gltT	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHOLCGFJ_01871	2.11e-148	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHOLCGFJ_01872	6.08e-225	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HHOLCGFJ_01873	4.15e-206	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HHOLCGFJ_01874	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HHOLCGFJ_01875	3.29e-94	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HHOLCGFJ_01876	1.48e-291	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HHOLCGFJ_01877	1.79e-156	yqfA	-	-	S	-	-	-	UPF0365 protein
HHOLCGFJ_01878	3.42e-107	-	-	-	-	-	-	-	-
HHOLCGFJ_01879	1.73e-63	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HHOLCGFJ_01880	1.71e-283	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HHOLCGFJ_01881	1.6e-221	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HHOLCGFJ_01882	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HHOLCGFJ_01883	1.68e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHOLCGFJ_01884	4.46e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HHOLCGFJ_01885	2.32e-94	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HHOLCGFJ_01886	1.22e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHOLCGFJ_01887	5.12e-25	-	-	-	S	-	-	-	YqzL-like protein
HHOLCGFJ_01888	3.69e-183	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HHOLCGFJ_01890	1.18e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HHOLCGFJ_01891	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HHOLCGFJ_01892	1.56e-145	ccpN	-	-	K	-	-	-	CBS domain
HHOLCGFJ_01893	1.01e-183	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HHOLCGFJ_01894	5.47e-103	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HHOLCGFJ_01895	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHOLCGFJ_01896	1.45e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHOLCGFJ_01897	4.86e-84	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HHOLCGFJ_01898	1.49e-180	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HHOLCGFJ_01899	5.88e-257	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHOLCGFJ_01900	9.03e-229	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HHOLCGFJ_01901	1.65e-111	-	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HHOLCGFJ_01902	9.84e-106	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HHOLCGFJ_01903	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHOLCGFJ_01904	1.31e-210	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HHOLCGFJ_01906	2.78e-274	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HHOLCGFJ_01907	9.77e-170	-	-	-	M	-	-	-	Transglycosylase SLT domain
HHOLCGFJ_01908	2.06e-185	zurA	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HHOLCGFJ_01909	9.87e-185	zurM	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HHOLCGFJ_01910	3.86e-102	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HHOLCGFJ_01911	1.79e-50	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HHOLCGFJ_01912	7.94e-145	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HHOLCGFJ_01913	1.19e-88	yqfX	-	-	S	-	-	-	membrane
HHOLCGFJ_01914	6.11e-256	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HHOLCGFJ_01915	2.73e-79	fimV	-	-	NU	ko:K08086,ko:K15845	ko05120,map05120	ko00000,ko00001	translation initiation factor activity
HHOLCGFJ_01916	8.7e-244	-	-	-	EGP	ko:K08221	-	ko00000,ko02000	Sugar (and other) transporter
HHOLCGFJ_01917	1.61e-196	ypuA	-	-	S	-	-	-	Secreted protein
HHOLCGFJ_01918	6.09e-152	-	-	-	O	-	-	-	NfeD-like C-terminal, partner-binding
HHOLCGFJ_01919	2.39e-253	XK27_00915	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHOLCGFJ_01920	0.0	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HHOLCGFJ_01926	1.93e-149	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HHOLCGFJ_01927	3.71e-298	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HHOLCGFJ_01928	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
HHOLCGFJ_01929	4.99e-101	-	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHOLCGFJ_01930	2.23e-80	-	-	-	-	-	-	-	-
HHOLCGFJ_01931	3.15e-162	-	-	-	G	-	-	-	PFAM Glycoside hydrolase 15-related
HHOLCGFJ_01932	6.04e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HHOLCGFJ_01933	1.17e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHOLCGFJ_01934	1.96e-183	-	-	-	S	-	-	-	Integral membrane protein DUF92
HHOLCGFJ_01935	1.47e-241	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HHOLCGFJ_01936	1.89e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HHOLCGFJ_01938	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HHOLCGFJ_01939	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Bacillus/Clostridium GerA spore germination protein
HHOLCGFJ_01940	8.61e-89	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HHOLCGFJ_01941	6.67e-109	-	-	-	-	-	-	-	-
HHOLCGFJ_01942	8.32e-12	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_01943	1.39e-229	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HHOLCGFJ_01944	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HHOLCGFJ_01945	1.15e-140	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HHOLCGFJ_01946	4.45e-38	-	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
HHOLCGFJ_01947	3.01e-181	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HHOLCGFJ_01948	2.28e-272	thiO	1.4.3.19	-	E	ko:K03153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HHOLCGFJ_01949	1.13e-185	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HHOLCGFJ_01950	1.18e-128	-	-	-	-	-	-	-	-
HHOLCGFJ_01951	5.85e-250	yqgV	-	-	S	-	-	-	Thiamine-binding protein
HHOLCGFJ_01952	3.87e-102	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHOLCGFJ_01953	1.25e-123	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HHOLCGFJ_01954	5.06e-179	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HHOLCGFJ_01955	4.16e-42	-	-	-	-	-	-	-	-
HHOLCGFJ_01956	2.49e-67	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_01957	2.58e-41	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HHOLCGFJ_01958	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHOLCGFJ_01959	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HHOLCGFJ_01960	1.37e-120	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHOLCGFJ_01961	1.23e-225	-	-	-	F	-	-	-	GHKL domain
HHOLCGFJ_01962	1.16e-217	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HHOLCGFJ_01963	6.58e-122	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_01965	3.72e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HHOLCGFJ_01966	3.28e-257	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HHOLCGFJ_01969	5.81e-91	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HHOLCGFJ_01970	9.53e-107	-	-	-	S	-	-	-	Pfam Polyketide cyclase dehydrase and lipid transport
HHOLCGFJ_01971	7.08e-96	ykuL	-	-	S	-	-	-	CBS domain
HHOLCGFJ_01972	3.53e-56	-	-	-	-	-	-	-	-
HHOLCGFJ_01973	0.0	apr	-	-	O	-	-	-	Belongs to the peptidase S8 family
HHOLCGFJ_01974	8.08e-192	yibQ	-	-	S	ko:K09798	-	ko00000	protein conserved in bacteria
HHOLCGFJ_01975	3.57e-62	tnrA	-	-	K	-	-	-	transcriptional
HHOLCGFJ_01976	6.24e-66	-	-	-	-	-	-	-	-
HHOLCGFJ_01978	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HHOLCGFJ_01979	2.33e-167	-	-	-	P	ko:K08714	-	ko00000,ko02000	Polycystin cation channel
HHOLCGFJ_01980	1.6e-186	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHOLCGFJ_01981	3.94e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HHOLCGFJ_01982	2.63e-264	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHOLCGFJ_01983	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HHOLCGFJ_01984	8.12e-238	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HHOLCGFJ_01985	2.91e-109	-	-	-	V	-	-	-	COG4767 Glycopeptide antibiotics resistance protein
HHOLCGFJ_01986	1.08e-71	ogt	-	-	L	ko:K07443	-	ko00000	Methyltransferase
HHOLCGFJ_01987	8.34e-127	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HHOLCGFJ_01988	2.45e-109	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HHOLCGFJ_01989	9.24e-122	-	-	-	S	-	-	-	UPF0316 protein
HHOLCGFJ_01990	1.73e-270	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HHOLCGFJ_01991	2.65e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHOLCGFJ_01992	8.65e-116	-	-	-	CO	-	-	-	Thioredoxin-like
HHOLCGFJ_01994	1.1e-121	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HHOLCGFJ_01995	3.53e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HHOLCGFJ_01996	2.66e-112	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HHOLCGFJ_01997	8.77e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HHOLCGFJ_01998	1.87e-217	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HHOLCGFJ_01999	8.89e-290	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHOLCGFJ_02000	7.28e-303	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HHOLCGFJ_02001	4.19e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HHOLCGFJ_02002	3.72e-154	-	-	-	J	-	-	-	translation release factor activity
HHOLCGFJ_02003	9.25e-306	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HHOLCGFJ_02004	4.52e-29	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HHOLCGFJ_02005	4.46e-74	-	-	-	-	-	-	-	-
HHOLCGFJ_02006	3.83e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HHOLCGFJ_02007	3.24e-182	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HHOLCGFJ_02008	2.39e-275	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHOLCGFJ_02009	7.27e-73	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HHOLCGFJ_02010	1.32e-97	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HHOLCGFJ_02011	9.34e-176	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHOLCGFJ_02012	7.14e-105	-	-	-	S	ko:K06405	-	ko00000	Pfam:SpoVA
HHOLCGFJ_02013	2.93e-235	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HHOLCGFJ_02014	8.69e-76	-	-	-	S	ko:K06407	-	ko00000	Pfam:SpoVA
HHOLCGFJ_02015	5.35e-139	spoVAEA	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
HHOLCGFJ_02016	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HHOLCGFJ_02017	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHOLCGFJ_02018	4.61e-106	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHOLCGFJ_02019	5.1e-207	ccpC	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02020	8.78e-262	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHOLCGFJ_02022	2.09e-266	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HHOLCGFJ_02023	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HHOLCGFJ_02024	1.16e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HHOLCGFJ_02025	1.25e-208	hgd	1.1.1.31, 1.1.1.60	-	I	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	ko00000,ko00001,ko01000	3-hydroxyisobutyrate dehydrogenase
HHOLCGFJ_02026	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHOLCGFJ_02027	1.05e-251	-	-	-	I	-	-	-	3-hydroxyisobutyryl-CoA hydrolase
HHOLCGFJ_02028	2.59e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HHOLCGFJ_02029	6.5e-289	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HHOLCGFJ_02030	1.39e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HHOLCGFJ_02031	6.41e-111	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HHOLCGFJ_02032	2.26e-161	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHOLCGFJ_02033	3.87e-126	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHOLCGFJ_02034	4.98e-137	-	-	-	K	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HHOLCGFJ_02035	0.0	acoD	-	-	C	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
HHOLCGFJ_02036	9.28e-218	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HHOLCGFJ_02037	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHOLCGFJ_02038	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HHOLCGFJ_02039	9.37e-60	-	-	-	S	-	-	-	ATP synthase, subunit b
HHOLCGFJ_02040	1.56e-161	-	-	-	S	-	-	-	membrane
HHOLCGFJ_02041	5.4e-59	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHOLCGFJ_02042	5.44e-104	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HHOLCGFJ_02043	5.15e-247	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HHOLCGFJ_02044	1.46e-73	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HHOLCGFJ_02045	5.42e-275	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HHOLCGFJ_02046	8.76e-131	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HHOLCGFJ_02047	2.1e-104	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HHOLCGFJ_02048	3.81e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HHOLCGFJ_02049	5.06e-126	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HHOLCGFJ_02050	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HHOLCGFJ_02051	1.35e-282	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HHOLCGFJ_02052	2.69e-167	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_02053	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_02055	2.85e-244	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_02056	3.67e-180	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HHOLCGFJ_02057	1.18e-127	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HHOLCGFJ_02059	5e-175	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HHOLCGFJ_02060	0.0	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HHOLCGFJ_02061	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLCGFJ_02062	2.77e-58	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HHOLCGFJ_02063	1.11e-242	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HHOLCGFJ_02064	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HHOLCGFJ_02065	3.63e-135	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HHOLCGFJ_02068	1.3e-69	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_02069	3.14e-52	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_02071	4.59e-289	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl Transferase
HHOLCGFJ_02072	5e-253	-	-	GT4	M	ko:K13678	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HHOLCGFJ_02073	1.94e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHOLCGFJ_02075	5.33e-287	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HHOLCGFJ_02076	1.44e-187	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HHOLCGFJ_02077	5.4e-222	ycgE	-	-	K	ko:K22491	-	ko00000,ko03000	MerR family transcriptional regulator
HHOLCGFJ_02078	8.17e-141	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HHOLCGFJ_02079	2.41e-165	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_02080	0.0	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HHOLCGFJ_02081	6.02e-246	-	-	-	-	-	-	-	-
HHOLCGFJ_02082	7.53e-304	gudB	1.4.1.2, 1.4.1.4	-	E	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HHOLCGFJ_02083	1.5e-231	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HHOLCGFJ_02084	1.05e-230	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HHOLCGFJ_02085	4.14e-146	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HHOLCGFJ_02086	8.25e-36	-	-	-	-	-	-	-	-
HHOLCGFJ_02087	3.88e-264	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HHOLCGFJ_02088	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HHOLCGFJ_02089	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HHOLCGFJ_02090	4.76e-215	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HHOLCGFJ_02091	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HHOLCGFJ_02092	2.95e-170	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HHOLCGFJ_02093	4.75e-138	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	1-acyl-sn-glycerol-3-phosphate acyltransferase
HHOLCGFJ_02094	5.04e-259	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HHOLCGFJ_02096	1.89e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HHOLCGFJ_02097	3.54e-133	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHOLCGFJ_02098	1.7e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HHOLCGFJ_02099	5.25e-54	-	-	-	S	-	-	-	Stage VI sporulation protein F
HHOLCGFJ_02100	8.81e-10	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HHOLCGFJ_02101	1.66e-174	yphF	-	-	-	-	-	-	-
HHOLCGFJ_02102	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HHOLCGFJ_02103	4.09e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HHOLCGFJ_02104	1.85e-48	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HHOLCGFJ_02105	6.72e-73	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	heptaprenyl diphosphate synthase
HHOLCGFJ_02106	3.84e-170	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HHOLCGFJ_02107	4.87e-203	ubiA	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HHOLCGFJ_02108	1.72e-207	mqnA	4.2.1.151	-	S	ko:K11782	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HHOLCGFJ_02109	2.93e-234	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HHOLCGFJ_02110	6.26e-101	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HHOLCGFJ_02111	2.4e-186	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HHOLCGFJ_02112	3.58e-281	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHOLCGFJ_02113	1.18e-253	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HHOLCGFJ_02114	6.53e-77	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HHOLCGFJ_02115	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHOLCGFJ_02116	9.12e-238	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHOLCGFJ_02117	3.1e-170	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HHOLCGFJ_02118	1.02e-147	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosylanthranilate isomerase activity
HHOLCGFJ_02119	1.04e-286	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HHOLCGFJ_02120	1.19e-190	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HHOLCGFJ_02121	9.88e-263	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HHOLCGFJ_02122	4.68e-259	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HHOLCGFJ_02123	2.85e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HHOLCGFJ_02124	1.95e-294	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HHOLCGFJ_02125	4.13e-127	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HHOLCGFJ_02126	3.85e-108	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HHOLCGFJ_02127	3.64e-119	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HHOLCGFJ_02128	8.39e-159	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HHOLCGFJ_02129	2.15e-192	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HHOLCGFJ_02130	1.8e-141	ypjA	-	-	S	-	-	-	membrane
HHOLCGFJ_02131	1.1e-180	-	-	-	S	-	-	-	Sporulation protein YpjB (SpoYpjB)
HHOLCGFJ_02132	1.21e-151	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HHOLCGFJ_02133	9.3e-273	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HHOLCGFJ_02134	3.86e-202	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HHOLCGFJ_02135	2.69e-79	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HHOLCGFJ_02136	1.23e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHOLCGFJ_02137	4.83e-98	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HHOLCGFJ_02138	1.12e-110	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_02139	6.15e-300	hint	6.5.1.3	-	S	ko:K14415	-	ko00000,ko01000,ko03016	tRNA-splicing ligase RtcB
HHOLCGFJ_02140	3.33e-51	-	-	-	-	-	-	-	-
HHOLCGFJ_02141	6.32e-99	yyaT	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_02142	3.29e-183	-	-	-	Q	-	-	-	Methyltransferase domain
HHOLCGFJ_02143	3.68e-69	-	-	-	-	-	-	-	-
HHOLCGFJ_02145	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHOLCGFJ_02146	3.05e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HHOLCGFJ_02147	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHOLCGFJ_02148	6.63e-173	yodH	-	-	Q	-	-	-	Methyltransferase
HHOLCGFJ_02149	3.24e-221	-	-	-	M	-	-	-	3D domain
HHOLCGFJ_02150	5.82e-232	-	-	-	M	-	-	-	3D domain
HHOLCGFJ_02151	4.7e-204	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHOLCGFJ_02152	7.25e-265	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HHOLCGFJ_02153	1.64e-196	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HHOLCGFJ_02154	7.48e-133	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HHOLCGFJ_02155	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HHOLCGFJ_02156	1.62e-186	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HHOLCGFJ_02157	4.57e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HHOLCGFJ_02158	7.37e-139	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HHOLCGFJ_02159	1.28e-151	-	-	CBM50	M	ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HHOLCGFJ_02160	8.06e-301	-	-	-	S	-	-	-	Acetyltransferase
HHOLCGFJ_02161	1.21e-135	yvdT	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02162	1.58e-238	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHOLCGFJ_02163	9.74e-176	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HHOLCGFJ_02164	4.73e-241	ywcH1	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHOLCGFJ_02165	2.28e-219	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HHOLCGFJ_02166	3.92e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HHOLCGFJ_02167	3.09e-78	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HHOLCGFJ_02168	0.0	asbA	-	-	Q	-	-	-	Siderophore biosynthesis protein
HHOLCGFJ_02169	0.0	asbB	-	-	Q	-	-	-	IucA / IucC family
HHOLCGFJ_02170	5.96e-304	asbC	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	AMP-binding enzyme C-terminal domain
HHOLCGFJ_02171	1.56e-55	asbD	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HHOLCGFJ_02172	1.98e-244	asbE	-	-	IQ	-	-	-	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHOLCGFJ_02173	3.22e-212	asbF	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
HHOLCGFJ_02174	4.55e-130	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	D,D-heptose 1,7-bisphosphate phosphatase
HHOLCGFJ_02175	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HHOLCGFJ_02176	4.91e-199	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HHOLCGFJ_02177	4.79e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HHOLCGFJ_02179	1.88e-193	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
HHOLCGFJ_02181	1.18e-72	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HHOLCGFJ_02182	5.41e-08	-	-	-	S	-	-	-	Putative methionine and alanine importer, small subunit
HHOLCGFJ_02183	0.0	-	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHOLCGFJ_02184	3.5e-206	-	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HHOLCGFJ_02185	4.21e-126	-	-	-	K	-	-	-	Virulence activator alpha C-term
HHOLCGFJ_02186	7.79e-112	-	-	-	S	-	-	-	Domain of unknown function (DUF4188)
HHOLCGFJ_02187	2.8e-277	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HHOLCGFJ_02188	6.15e-181	-	-	-	-	-	-	-	-
HHOLCGFJ_02189	3.16e-183	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HHOLCGFJ_02190	1.46e-69	-	-	-	-	-	-	-	-
HHOLCGFJ_02191	6.14e-15	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HHOLCGFJ_02192	9.25e-217	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_02193	3.67e-180	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HHOLCGFJ_02194	3.17e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HHOLCGFJ_02196	1.04e-39	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HHOLCGFJ_02197	2.97e-226	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
HHOLCGFJ_02198	2.93e-92	-	-	-	S	-	-	-	Bacterial PH domain
HHOLCGFJ_02199	8.41e-28	-	-	-	S	-	-	-	Belongs to the LOG family
HHOLCGFJ_02200	1.84e-116	-	-	-	C	-	-	-	HEAT repeats
HHOLCGFJ_02201	1.2e-163	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	This enzyme is an effector of chloramphenicol resistance in bacteria
HHOLCGFJ_02202	2.35e-138	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HHOLCGFJ_02203	1.01e-48	-	-	-	K	-	-	-	COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
HHOLCGFJ_02204	7.87e-146	-	-	-	S	-	-	-	Golgi phosphoprotein 3 (GPP34)
HHOLCGFJ_02205	5.87e-194	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HHOLCGFJ_02206	2.56e-180	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HHOLCGFJ_02207	1.27e-172	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HHOLCGFJ_02208	1.97e-259	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HHOLCGFJ_02209	1.18e-109	yocK	-	-	T	-	-	-	general stress protein
HHOLCGFJ_02210	1.57e-77	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2200)
HHOLCGFJ_02211	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHOLCGFJ_02212	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHOLCGFJ_02213	1.79e-92	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HHOLCGFJ_02214	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HHOLCGFJ_02215	1.31e-243	opuBA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HHOLCGFJ_02216	2.92e-188	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_02217	8.78e-130	-	-	-	U	-	-	-	MarC family integral membrane protein
HHOLCGFJ_02218	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HHOLCGFJ_02219	9.71e-70	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HHOLCGFJ_02220	1.17e-124	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HHOLCGFJ_02221	5.03e-278	-	-	-	G	-	-	-	Transmembrane secretion effector
HHOLCGFJ_02223	1.75e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HHOLCGFJ_02224	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HHOLCGFJ_02225	1.12e-68	-	-	-	-	-	-	-	-
HHOLCGFJ_02226	8.12e-91	-	-	-	S	-	-	-	Src homology 3 domains
HHOLCGFJ_02227	0.0	-	-	-	P	-	-	-	Spore gernimation protein GerA
HHOLCGFJ_02228	6.85e-255	-	-	-	E	-	-	-	Spore germination protein
HHOLCGFJ_02229	4.15e-258	-	-	-	S	ko:K06308	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HHOLCGFJ_02231	3.68e-223	-	-	-	NT	-	-	-	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HHOLCGFJ_02232	6.96e-83	-	-	-	-	-	-	-	-
HHOLCGFJ_02233	1.04e-83	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HHOLCGFJ_02234	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HHOLCGFJ_02235	1.77e-237	-	-	-	S	-	-	-	Oxidoreductase
HHOLCGFJ_02236	1.63e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HHOLCGFJ_02237	4.7e-52	-	-	-	-	-	-	-	-
HHOLCGFJ_02238	5.36e-271	-	-	-	L	ko:K07496	-	ko00000	Transposase
HHOLCGFJ_02239	8.9e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
HHOLCGFJ_02240	2.65e-64	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHOLCGFJ_02241	3.49e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HHOLCGFJ_02242	3.2e-07	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HHOLCGFJ_02243	8.95e-293	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HHOLCGFJ_02244	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HHOLCGFJ_02245	0.0	pepF	-	-	E	-	-	-	oligoendopeptidase F
HHOLCGFJ_02246	0.0	gerAA	-	-	EG	ko:K06288,ko:K06310	-	ko00000	Spore germination protein
HHOLCGFJ_02247	1.07e-242	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HHOLCGFJ_02248	2.11e-272	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HHOLCGFJ_02249	6.78e-129	-	-	-	-	-	-	-	-
HHOLCGFJ_02250	5.31e-149	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HHOLCGFJ_02251	8.79e-239	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HHOLCGFJ_02252	1.41e-28	-	-	-	-	-	-	-	-
HHOLCGFJ_02253	9.4e-198	ycsE	-	-	S	-	-	-	hydrolases of the HAD superfamily
HHOLCGFJ_02254	1.52e-115	-	-	-	-	-	-	-	-
HHOLCGFJ_02255	2.9e-05	-	-	-	S	ko:K06376	-	ko00000	Spo0E like sporulation regulatory protein
HHOLCGFJ_02256	1.46e-207	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHOLCGFJ_02257	9.99e-86	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HHOLCGFJ_02258	3.24e-53	-	-	-	-	-	-	-	-
HHOLCGFJ_02259	2.85e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
HHOLCGFJ_02260	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HHOLCGFJ_02261	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HHOLCGFJ_02262	3.36e-198	telA	-	-	P	-	-	-	Belongs to the TelA family
HHOLCGFJ_02263	6.2e-215	-	-	-	-	-	-	-	-
HHOLCGFJ_02264	3.1e-246	-	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HHOLCGFJ_02265	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HHOLCGFJ_02266	4.28e-112	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HHOLCGFJ_02267	3.18e-41	-	-	-	-	-	-	-	-
HHOLCGFJ_02268	2.15e-201	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HHOLCGFJ_02269	1.7e-176	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HHOLCGFJ_02270	1.03e-96	-	-	-	CO	-	-	-	Thioredoxin-like
HHOLCGFJ_02271	1.09e-100	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HHOLCGFJ_02272	1.15e-73	yusE	-	-	CO	-	-	-	cell redox homeostasis
HHOLCGFJ_02273	3.94e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHOLCGFJ_02274	1.13e-125	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HHOLCGFJ_02275	6.68e-302	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHOLCGFJ_02276	2.9e-26	-	-	-	-	-	-	-	-
HHOLCGFJ_02277	4.37e-81	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
HHOLCGFJ_02278	4.53e-117	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HHOLCGFJ_02280	3e-220	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HHOLCGFJ_02281	2.96e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHOLCGFJ_02282	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HHOLCGFJ_02285	5.06e-198	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHOLCGFJ_02286	1.13e-276	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HHOLCGFJ_02287	8.98e-250	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HHOLCGFJ_02288	0.0	-	-	-	C	ko:K13796	-	ko00000	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
HHOLCGFJ_02289	2.3e-255	icd	1.1.1.41, 1.1.1.42, 1.1.1.85	-	CE	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HHOLCGFJ_02290	3.92e-215	yraN	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02291	1.73e-270	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HHOLCGFJ_02292	0.0	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctA family
HHOLCGFJ_02293	9.21e-89	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
HHOLCGFJ_02294	6.36e-278	yraM	-	-	S	-	-	-	PrpF protein
HHOLCGFJ_02295	1.47e-79	-	-	-	K	-	-	-	GntR family transcriptional regulator
HHOLCGFJ_02296	1.02e-203	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HHOLCGFJ_02297	1.56e-22	-	-	-	-	-	-	-	-
HHOLCGFJ_02298	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HHOLCGFJ_02299	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HHOLCGFJ_02300	2.22e-143	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HHOLCGFJ_02301	1.14e-183	cbiX	4.99.1.3	-	C	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	CbiX
HHOLCGFJ_02302	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HHOLCGFJ_02303	1.03e-144	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HHOLCGFJ_02304	2.4e-237	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HHOLCGFJ_02305	2.13e-279	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HHOLCGFJ_02306	3.86e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HHOLCGFJ_02307	4.7e-271	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HHOLCGFJ_02308	3.72e-99	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HHOLCGFJ_02309	4.35e-238	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HHOLCGFJ_02310	3e-254	-	-	-	S	-	-	-	oxidoreductase
HHOLCGFJ_02311	3.2e-287	-	1.1.1.18, 1.1.1.369, 1.1.1.371	-	S	ko:K00010,ko:K16044	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_02312	2.59e-158	kdgR	-	-	K	-	-	-	FCD
HHOLCGFJ_02313	8.5e-207	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HHOLCGFJ_02314	7.11e-124	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HHOLCGFJ_02315	1.01e-171	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HHOLCGFJ_02316	1e-174	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHOLCGFJ_02317	1.31e-267	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HHOLCGFJ_02318	1.05e-229	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLCGFJ_02319	6.32e-122	ssuE	1.5.1.38, 1.5.1.45	-	S	ko:K00299,ko:K16902	ko00380,ko00740,ko00920,ko01100,map00380,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
HHOLCGFJ_02320	1.5e-09	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HHOLCGFJ_02321	4e-71	-	-	-	-	-	-	-	-
HHOLCGFJ_02322	5.71e-159	yflK	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_02323	2.98e-216	-	2.7.1.196, 2.7.1.205	-	K	ko:K02760,ko:K20480	ko00500,ko02024,ko02060,map00500,map02024,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	sequence-specific DNA binding
HHOLCGFJ_02324	5.07e-299	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
HHOLCGFJ_02326	1.19e-314	-	-	-	-	-	-	-	-
HHOLCGFJ_02327	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHOLCGFJ_02328	1.2e-59	M1-594	-	-	S	-	-	-	Thiamine-binding protein
HHOLCGFJ_02330	2.48e-274	chrA	-	-	P	ko:K07240	-	ko00000,ko02000	chromate transporter, chromate ion transporter
HHOLCGFJ_02331	2.4e-42	-	5.3.2.6	-	S	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Tautomerase enzyme
HHOLCGFJ_02332	5.55e-272	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HHOLCGFJ_02333	3.63e-220	-	-	-	E	-	-	-	Thermophilic metalloprotease (M29)
HHOLCGFJ_02334	9.74e-146	-	-	-	E	ko:K14591	-	ko00000	AroM protein
HHOLCGFJ_02335	1.21e-216	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
HHOLCGFJ_02336	7.03e-246	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HHOLCGFJ_02337	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HHOLCGFJ_02338	1.6e-143	-	-	-	E	-	-	-	Asp/Glu/Hydantoin racemase
HHOLCGFJ_02339	0.0	-	-	-	KT	ko:K09684	-	ko00000,ko03000	PucR C-terminal helix-turn-helix domain
HHOLCGFJ_02340	7.22e-283	yrbE	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_02341	5.09e-161	-	-	-	S	ko:K09992	-	ko00000	Trehalose utilisation
HHOLCGFJ_02342	3.43e-281	xylR5	-	-	GK	-	-	-	ROK family
HHOLCGFJ_02343	5.24e-259	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HHOLCGFJ_02344	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HHOLCGFJ_02345	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HHOLCGFJ_02346	5.63e-176	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02347	4.76e-308	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HHOLCGFJ_02348	4.12e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
HHOLCGFJ_02349	1.5e-242	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_02350	1.36e-242	-	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_02351	3.26e-197	-	-	-	EP	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_02352	4.39e-219	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_02353	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HHOLCGFJ_02354	1.25e-262	-	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
HHOLCGFJ_02355	2.5e-280	hutI	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
HHOLCGFJ_02356	1.94e-45	-	-	-	D	-	-	-	nuclear chromosome segregation
HHOLCGFJ_02357	4.65e-256	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HHOLCGFJ_02358	6.53e-158	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HHOLCGFJ_02359	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02360	5.44e-197	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HHOLCGFJ_02361	5.62e-226	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02362	0.0	aguA	3.2.1.139	-	G	ko:K01235	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 67 family
HHOLCGFJ_02363	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HHOLCGFJ_02365	2.97e-220	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHOLCGFJ_02366	1.03e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHOLCGFJ_02367	3.91e-145	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HHOLCGFJ_02368	6.67e-202	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HHOLCGFJ_02369	3.59e-284	hmrA	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
HHOLCGFJ_02370	9.05e-273	-	-	-	G	-	-	-	Transmembrane secretion effector
HHOLCGFJ_02371	2.69e-211	-	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HHOLCGFJ_02372	1.02e-151	-	-	-	K	-	-	-	FCD domain
HHOLCGFJ_02373	3.24e-292	bbsF_2	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	acyl-CoA transferases carnitine dehydratase
HHOLCGFJ_02374	3.63e-28	-	-	-	-	-	-	-	-
HHOLCGFJ_02375	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
HHOLCGFJ_02376	2.72e-194	-	-	-	-	-	-	-	-
HHOLCGFJ_02377	1.94e-126	-	-	-	-	-	-	-	-
HHOLCGFJ_02378	3.56e-138	-	-	-	-	-	-	-	-
HHOLCGFJ_02379	0.0	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HHOLCGFJ_02382	0.0	-	-	-	V	-	-	-	SNF2 family N-terminal domain
HHOLCGFJ_02383	1.74e-156	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HHOLCGFJ_02384	1.28e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HHOLCGFJ_02385	6.47e-145	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
HHOLCGFJ_02386	1.65e-102	-	-	-	S	-	-	-	VanZ like family
HHOLCGFJ_02387	3.89e-263	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HHOLCGFJ_02388	2.7e-145	-	-	-	S	-	-	-	Predicted membrane protein (DUF2306)
HHOLCGFJ_02389	2.64e-243	-	-	-	K	-	-	-	DJ-1/PfpI family
HHOLCGFJ_02390	1.51e-163	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_02391	2.78e-309	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HHOLCGFJ_02392	8.46e-160	-	-	-	S	ko:K02351	-	ko00000	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
HHOLCGFJ_02393	9.8e-116	-	-	-	S	-	-	-	Predicted membrane protein (DUF2243)
HHOLCGFJ_02394	1.35e-200	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HHOLCGFJ_02395	1.79e-212	dgoD	4.2.1.6	-	M	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HHOLCGFJ_02396	5.47e-144	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HHOLCGFJ_02397	7.37e-224	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HHOLCGFJ_02398	1.32e-168	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
HHOLCGFJ_02399	5.2e-145	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HHOLCGFJ_02400	3.63e-309	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
HHOLCGFJ_02401	1.13e-36	-	-	-	-	-	-	-	-
HHOLCGFJ_02402	6.43e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HHOLCGFJ_02403	4.13e-314	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HHOLCGFJ_02404	3.19e-35	ybbJ	-	-	K	-	-	-	acetyltransferase
HHOLCGFJ_02405	7.2e-44	ybbJ	-	-	J	-	-	-	acetyltransferase
HHOLCGFJ_02406	0.0	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHOLCGFJ_02407	5.27e-169	-	-	-	M	-	-	-	Glycosyl transferase family 2
HHOLCGFJ_02408	4.27e-222	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HHOLCGFJ_02409	2.94e-171	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
HHOLCGFJ_02410	5.28e-202	-	-	-	-	-	-	-	-
HHOLCGFJ_02411	4.39e-244	-	-	-	M	-	-	-	Glycosyl transferases group 1
HHOLCGFJ_02412	1.87e-219	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
HHOLCGFJ_02413	2.64e-128	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHOLCGFJ_02414	1.2e-283	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HHOLCGFJ_02415	6.9e-116	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
HHOLCGFJ_02417	2.49e-179	yafE	-	-	Q	-	-	-	methyltransferase
HHOLCGFJ_02419	0.0	-	1.3.98.3	-	H	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of porphyrin-containing compound
HHOLCGFJ_02420	0.0	-	-	-	I	-	-	-	radical SAM domain protein
HHOLCGFJ_02422	2.53e-05	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HHOLCGFJ_02423	1.39e-21	-	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HHOLCGFJ_02424	4.23e-117	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HHOLCGFJ_02425	4.95e-160	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HHOLCGFJ_02426	3.02e-310	ykoH	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_02427	1.17e-106	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_02428	3.29e-181	-	-	-	S	-	-	-	carbohydrate derivative metabolic process
HHOLCGFJ_02429	1.89e-166	frlR3	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HHOLCGFJ_02430	4.61e-293	-	-	-	JM	-	-	-	Bacterial transferase hexapeptide (six repeats)
HHOLCGFJ_02431	1.03e-126	-	-	-	M	-	-	-	3D domain
HHOLCGFJ_02432	2.43e-88	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HHOLCGFJ_02433	2.55e-256	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLCGFJ_02434	4.62e-170	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02435	1.36e-171	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02436	1.54e-124	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HHOLCGFJ_02437	7.49e-148	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_02438	2.93e-13	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HHOLCGFJ_02439	4e-236	-	-	-	S	ko:K09704	-	ko00000	Glycosyl hydrolase
HHOLCGFJ_02440	3.36e-313	-	2.3.1.204, 3.2.1.24	GH38	G	ko:K01191,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HHOLCGFJ_02441	1.94e-233	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HHOLCGFJ_02442	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HHOLCGFJ_02443	3.86e-263	-	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HHOLCGFJ_02444	1.74e-110	-	-	-	-	-	-	-	-
HHOLCGFJ_02445	1.27e-105	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HHOLCGFJ_02446	4.18e-135	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HHOLCGFJ_02447	3.48e-78	-	-	-	K	-	-	-	TetR family transcriptional regulator
HHOLCGFJ_02448	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HHOLCGFJ_02449	0.0	gmuD	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHOLCGFJ_02450	5.36e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_02451	1.37e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHOLCGFJ_02452	3.7e-60	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_02453	3.76e-179	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
HHOLCGFJ_02454	8.01e-106	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
HHOLCGFJ_02455	4.66e-87	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
HHOLCGFJ_02456	3.53e-275	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HHOLCGFJ_02457	7.98e-156	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HHOLCGFJ_02458	1.05e-156	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HHOLCGFJ_02459	3.23e-218	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
HHOLCGFJ_02460	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHOLCGFJ_02461	6.57e-107	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
HHOLCGFJ_02462	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
HHOLCGFJ_02463	2.43e-241	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HHOLCGFJ_02464	1.71e-241	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mannonate dehydratase activity
HHOLCGFJ_02465	1.22e-70	-	-	-	-	-	-	-	-
HHOLCGFJ_02466	0.0	-	-	-	-	-	-	-	-
HHOLCGFJ_02467	7.18e-170	-	-	-	-	-	-	-	-
HHOLCGFJ_02468	1.78e-135	-	-	-	-	-	-	-	-
HHOLCGFJ_02469	4.76e-66	-	-	-	F	-	-	-	NUDIX domain
HHOLCGFJ_02470	1.33e-128	-	-	-	S	-	-	-	Tetratricopeptide repeat
HHOLCGFJ_02471	5.55e-304	-	-	-	V	-	-	-	MatE
HHOLCGFJ_02472	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HHOLCGFJ_02473	2.89e-291	-	-	-	C	ko:K03300	-	ko00000	Citrate transporter
HHOLCGFJ_02474	1.27e-70	-	-	-	-	-	-	-	-
HHOLCGFJ_02475	7.05e-306	-	-	-	E	-	-	-	Acyclic terpene utilisation family protein AtuA
HHOLCGFJ_02476	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
HHOLCGFJ_02477	5.76e-134	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HHOLCGFJ_02478	1.2e-203	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HHOLCGFJ_02479	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHOLCGFJ_02481	1.72e-121	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HHOLCGFJ_02482	7.44e-238	fruA2	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
HHOLCGFJ_02483	6.25e-63	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HHOLCGFJ_02484	1.83e-101	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHOLCGFJ_02485	3.06e-204	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HHOLCGFJ_02486	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
HHOLCGFJ_02487	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HHOLCGFJ_02488	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HHOLCGFJ_02489	4.36e-284	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
HHOLCGFJ_02490	4.43e-105	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HHOLCGFJ_02491	3.33e-242	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HHOLCGFJ_02492	5.8e-248	-	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HHOLCGFJ_02493	6.19e-209	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_02494	0.0	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02495	2.34e-212	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02496	2.45e-182	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02497	2.93e-86	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
HHOLCGFJ_02498	5.4e-311	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
HHOLCGFJ_02499	2.79e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HHOLCGFJ_02500	0.0	-	-	-	S	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHOLCGFJ_02501	2.99e-247	-	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HHOLCGFJ_02502	2.25e-207	iolJ	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HHOLCGFJ_02503	6.31e-252	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HHOLCGFJ_02504	3.02e-226	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HHOLCGFJ_02505	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HHOLCGFJ_02506	9.35e-228	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HHOLCGFJ_02507	1.41e-199	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HHOLCGFJ_02508	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHOLCGFJ_02509	2.48e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HHOLCGFJ_02510	3.01e-309	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HHOLCGFJ_02511	1.47e-130	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02512	2.06e-78	ykkC_1	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HHOLCGFJ_02513	2.37e-62	ykkD_1	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HHOLCGFJ_02514	2.49e-239	-	-	-	KTV	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HHOLCGFJ_02515	3.89e-148	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HHOLCGFJ_02516	3.11e-106	-	-	-	S	-	-	-	Putative small multi-drug export protein
HHOLCGFJ_02518	7.66e-64	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HHOLCGFJ_02519	0.0	melA7	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HHOLCGFJ_02520	3.63e-253	araH	-	-	G	ko:K10544,ko:K10547	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHOLCGFJ_02521	0.0	araG	3.6.3.17	-	G	ko:K10548	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HHOLCGFJ_02522	1.96e-252	chvE	-	-	G	ko:K10546	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHOLCGFJ_02523	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HHOLCGFJ_02524	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HHOLCGFJ_02525	2.15e-176	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HHOLCGFJ_02526	3.27e-276	egsA	1.1.1.261	-	C	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HHOLCGFJ_02527	2.67e-179	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HHOLCGFJ_02528	8.24e-217	rhaR1	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_02529	9.7e-223	M1-640	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02530	1.33e-140	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HHOLCGFJ_02531	4.49e-196	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02532	1.25e-204	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02533	5.82e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02534	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HHOLCGFJ_02535	1.2e-200	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02536	2.9e-189	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02537	2.66e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02538	0.0	yesW	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HHOLCGFJ_02540	1.14e-163	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HHOLCGFJ_02541	1.25e-206	-	-	-	K	-	-	-	LysR substrate binding domain
HHOLCGFJ_02542	1.39e-152	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_02543	3.3e-298	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HHOLCGFJ_02544	2.9e-255	-	-	-	I	-	-	-	Acyltransferase family
HHOLCGFJ_02545	4.88e-200	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02546	2.9e-225	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02547	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02548	2.34e-265	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HHOLCGFJ_02549	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_02550	6.96e-286	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HHOLCGFJ_02551	4.9e-201	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHOLCGFJ_02552	1.16e-284	-	-	-	EM	-	-	-	Protein of unknown function (DUF993)
HHOLCGFJ_02553	7.06e-294	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HHOLCGFJ_02554	2.13e-193	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_02555	9.68e-291	-	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HHOLCGFJ_02556	1.21e-73	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HHOLCGFJ_02557	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
HHOLCGFJ_02558	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HHOLCGFJ_02559	1.14e-231	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_02560	0.0	-	-	-	E	-	-	-	amino acid
HHOLCGFJ_02561	6.05e-220	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HHOLCGFJ_02562	7.81e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHOLCGFJ_02563	2.9e-154	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHOLCGFJ_02564	6.82e-183	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_02565	1.03e-264	-	-	-	-	-	-	-	-
HHOLCGFJ_02566	4.08e-137	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HHOLCGFJ_02567	4.12e-254	-	1.1.1.361	-	S	ko:K18652	-	ko00000,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_02568	1.56e-230	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHOLCGFJ_02569	3.96e-166	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HHOLCGFJ_02570	1.06e-200	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HHOLCGFJ_02571	1.33e-226	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02572	1.02e-120	-	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HHOLCGFJ_02573	2.94e-194	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HHOLCGFJ_02574	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02575	7.67e-273	-	-	-	EGP	ko:K08162	-	ko00000,ko02000	Major Facilitator Superfamily
HHOLCGFJ_02576	2.4e-181	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HHOLCGFJ_02577	1.15e-302	ugpB	-	-	G	ko:K02027,ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter substrate-binding protein
HHOLCGFJ_02578	5.39e-184	ugpE	-	-	P	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter permease
HHOLCGFJ_02579	5.95e-211	ugpA	-	-	G	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HHOLCGFJ_02580	4.35e-262	ugpC	3.6.3.20	-	P	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_02581	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HHOLCGFJ_02582	5.99e-308	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHOLCGFJ_02583	4.21e-100	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HHOLCGFJ_02584	1.6e-249	yneE	-	-	K	-	-	-	Arabinose-binding domain of AraC transcription regulator, N-term
HHOLCGFJ_02585	4.3e-187	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHOLCGFJ_02587	1.15e-58	-	-	-	-	-	-	-	-
HHOLCGFJ_02588	3.23e-298	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HHOLCGFJ_02589	5.3e-49	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
HHOLCGFJ_02591	7.9e-39	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HHOLCGFJ_02592	6.29e-263	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HHOLCGFJ_02593	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HHOLCGFJ_02594	0.0	alkK	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHOLCGFJ_02596	1.91e-248	-	3.6.3.20	-	P	ko:K05816	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_02597	2.4e-190	-	-	-	P	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHOLCGFJ_02598	2.75e-211	-	-	-	G	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HHOLCGFJ_02599	1.99e-196	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHOLCGFJ_02600	0.0	-	-	-	G	ko:K02027,ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter substrate-binding protein
HHOLCGFJ_02601	1.59e-99	ectC	4.2.1.108	-	S	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
HHOLCGFJ_02602	7.81e-316	ectB	2.6.1.76	-	E	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHOLCGFJ_02603	1.77e-116	ectA	2.3.1.178	-	K	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-2,4-diaminobutyric acid acetyltransferase
HHOLCGFJ_02604	2.63e-90	-	-	-	-	-	-	-	-
HHOLCGFJ_02605	0.0	-	-	-	EG	ko:K06295	-	ko00000	Bacillus/Clostridium GerA spore germination protein
HHOLCGFJ_02606	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHOLCGFJ_02607	1.25e-264	-	-	-	C	ko:K19954	-	ko00000,ko01000	alcohol dehydrogenase
HHOLCGFJ_02608	1.14e-224	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HHOLCGFJ_02609	1.07e-298	-	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HHOLCGFJ_02610	1.07e-281	adhB	1.1.1.1, 1.1.1.202	-	C	ko:K00001,ko:K00086	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HHOLCGFJ_02611	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
HHOLCGFJ_02612	7.43e-29	-	-	-	-	-	-	-	-
HHOLCGFJ_02613	5.57e-71	fdx5	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
HHOLCGFJ_02614	4.72e-127	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HHOLCGFJ_02616	1.34e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HHOLCGFJ_02617	9.27e-209	manA3	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Endoglucanase
HHOLCGFJ_02618	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02619	3.47e-215	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HHOLCGFJ_02620	3.26e-199	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02621	7.75e-213	-	-	-	GK	-	-	-	ROK family
HHOLCGFJ_02622	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HHOLCGFJ_02623	1.58e-239	purR15	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HHOLCGFJ_02624	1.34e-256	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HHOLCGFJ_02625	3.64e-306	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_02626	5.04e-201	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHOLCGFJ_02627	0.0	-	-	-	K	-	-	-	Propionate catabolism activator
HHOLCGFJ_02629	4.37e-218	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HHOLCGFJ_02630	6.07e-310	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
HHOLCGFJ_02631	3.05e-235	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
HHOLCGFJ_02632	3.25e-190	murR	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02633	0.0	yvcC1	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HHOLCGFJ_02634	1.33e-181	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHOLCGFJ_02635	1.27e-224	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HHOLCGFJ_02636	5.97e-241	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HHOLCGFJ_02637	2.53e-107	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HHOLCGFJ_02638	1e-276	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HHOLCGFJ_02639	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HHOLCGFJ_02642	1.98e-133	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HHOLCGFJ_02643	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHOLCGFJ_02644	9.74e-224	yueF	-	-	S	-	-	-	transporter activity
HHOLCGFJ_02645	2.62e-111	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
HHOLCGFJ_02646	4.11e-11	-	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HHOLCGFJ_02647	3.19e-127	flaR	-	-	F	-	-	-	topology modulation protein
HHOLCGFJ_02648	3.5e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHOLCGFJ_02649	2.75e-210	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
HHOLCGFJ_02650	3.84e-153	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HHOLCGFJ_02651	0.0	-	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HHOLCGFJ_02652	8.04e-111	-	2.3.1.128	-	J	ko:K03789,ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HHOLCGFJ_02653	4.05e-147	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HHOLCGFJ_02654	9.99e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HHOLCGFJ_02655	4.71e-87	-	-	-	-	-	-	-	-
HHOLCGFJ_02656	1.36e-145	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_02657	2.01e-167	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHOLCGFJ_02658	2.01e-185	-	-	-	EG	-	-	-	EamA-like transporter family
HHOLCGFJ_02659	1.46e-156	-	-	-	Q	-	-	-	SAM-dependent methyltransferase
HHOLCGFJ_02660	2.32e-234	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HHOLCGFJ_02661	2.91e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HHOLCGFJ_02662	6.21e-119	-	-	-	-	-	-	-	-
HHOLCGFJ_02663	3.88e-118	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HHOLCGFJ_02664	3.91e-262	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
HHOLCGFJ_02665	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HHOLCGFJ_02666	3.43e-78	-	-	-	K	ko:K21903	-	ko00000,ko03000	transcriptional
HHOLCGFJ_02667	7.76e-185	-	-	-	H	ko:K17882	-	ko00000,ko01000,ko01504	KNTase C-terminal domain
HHOLCGFJ_02668	1.29e-83	blaI	-	-	K	ko:K02171,ko:K02546	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HHOLCGFJ_02669	0.0	mecR1	-	-	KTV	ko:K02172,ko:K02547	ko01501,map01501	ko00000,ko00001,ko00002,ko01002,ko01504	BlaR1 peptidase M56
HHOLCGFJ_02670	7.93e-196	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HHOLCGFJ_02671	1.83e-230	-	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHOLCGFJ_02672	1.97e-128	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HHOLCGFJ_02673	2.17e-207	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_02674	4.39e-76	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HHOLCGFJ_02675	3.41e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HHOLCGFJ_02676	1.41e-80	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HHOLCGFJ_02677	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HHOLCGFJ_02678	7.66e-292	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HHOLCGFJ_02679	5.04e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_02680	3.78e-248	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HHOLCGFJ_02681	6.12e-157	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HHOLCGFJ_02682	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HHOLCGFJ_02683	3.27e-183	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_02684	3.86e-282	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HHOLCGFJ_02685	1.43e-96	-	-	-	K	-	-	-	SpoVT / AbrB like domain
HHOLCGFJ_02686	0.0	-	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HHOLCGFJ_02688	4.98e-222	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HHOLCGFJ_02689	2.52e-199	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_02690	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHOLCGFJ_02692	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHOLCGFJ_02693	3.74e-284	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_02694	6.84e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHOLCGFJ_02695	1.98e-156	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HHOLCGFJ_02696	5.59e-128	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HHOLCGFJ_02703	1.62e-11	-	-	-	-	-	-	-	-
HHOLCGFJ_02705	0.000115	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HHOLCGFJ_02706	0.0	gsiB_3	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HHOLCGFJ_02707	1.64e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HHOLCGFJ_02708	1.36e-243	bdhA	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HHOLCGFJ_02709	4e-105	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_02710	2.13e-96	-	-	-	-	-	-	-	-
HHOLCGFJ_02711	1.51e-34	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HHOLCGFJ_02712	6.09e-57	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HHOLCGFJ_02713	8.76e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HHOLCGFJ_02714	1.24e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HHOLCGFJ_02715	1.12e-243	-	-	-	EGP	-	-	-	MFS/sugar transport protein
HHOLCGFJ_02716	1.59e-175	-	-	-	KT	-	-	-	Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding
HHOLCGFJ_02717	2.65e-239	-	-	-	M	-	-	-	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HHOLCGFJ_02718	5.55e-212	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HHOLCGFJ_02719	4.65e-186	-	-	-	K	-	-	-	MerR family transcriptional regulator
HHOLCGFJ_02720	1.27e-94	-	-	-	-	-	-	-	-
HHOLCGFJ_02721	4.58e-151	-	-	-	O	-	-	-	Sap, sulfolipid-1-addressing protein
HHOLCGFJ_02722	1.16e-208	-	2.7.1.190	-	S	ko:K17910	-	ko00000,ko01000,ko01504	Protein of unknown function (DUF1679)
HHOLCGFJ_02723	1e-176	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHOLCGFJ_02724	3.1e-110	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HHOLCGFJ_02725	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HHOLCGFJ_02728	2.8e-206	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HHOLCGFJ_02729	1.62e-206	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHOLCGFJ_02730	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HHOLCGFJ_02731	1.62e-83	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HHOLCGFJ_02732	9.82e-202	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHOLCGFJ_02733	6.64e-233	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HHOLCGFJ_02734	1.81e-225	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HHOLCGFJ_02736	5.23e-92	-	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HHOLCGFJ_02737	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HHOLCGFJ_02738	1.63e-161	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HHOLCGFJ_02739	4.4e-170	-	-	-	-	-	-	-	-
HHOLCGFJ_02740	3.57e-174	-	-	-	S	-	-	-	ABC-2 family transporter protein
HHOLCGFJ_02741	3.66e-166	pstB13	-	-	V	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HHOLCGFJ_02742	3.93e-134	-	-	-	H	-	-	-	Flavoprotein
HHOLCGFJ_02743	0.0	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C-like protein
HHOLCGFJ_02744	0.0	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
HHOLCGFJ_02746	4.11e-222	XK27_06795	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HHOLCGFJ_02747	0.0	yvcC1	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HHOLCGFJ_02750	1.04e-71	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_02751	7.57e-135	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HHOLCGFJ_02752	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HHOLCGFJ_02753	6.6e-99	-	-	-	T	-	-	-	Bacterial transcriptional activator domain
HHOLCGFJ_02754	1.38e-258	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_02756	7.22e-233	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_02757	1.11e-249	rspA	4.2.1.8	-	M	ko:K08323	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HHOLCGFJ_02758	1.15e-117	-	-	-	K	-	-	-	Helix-turn-helix domain
HHOLCGFJ_02759	3.22e-26	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHOLCGFJ_02760	0.0	ramA	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase
HHOLCGFJ_02761	6.73e-135	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02762	3.25e-150	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02763	7.08e-168	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
HHOLCGFJ_02765	3.46e-48	-	-	-	T	-	-	-	helix_turn_helix, arabinose operon control protein
HHOLCGFJ_02766	2.87e-152	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_02767	9.44e-109	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HHOLCGFJ_02768	8.91e-153	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02769	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HHOLCGFJ_02770	2.41e-69	yqjY	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
HHOLCGFJ_02771	3.4e-173	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
HHOLCGFJ_02772	1.49e-40	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_02773	1.55e-79	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HHOLCGFJ_02775	1.74e-152	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HHOLCGFJ_02776	5.07e-202	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
HHOLCGFJ_02777	3.37e-250	-	1.1.1.14, 1.1.1.251	-	C	ko:K00008,ko:K00094	ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
HHOLCGFJ_02778	1.44e-311	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3775 Phosphotransferase system, galactitol-specific IIC component
HHOLCGFJ_02779	6.76e-56	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
HHOLCGFJ_02780	2.78e-103	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHOLCGFJ_02781	2.05e-183	-	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HHOLCGFJ_02782	1.28e-228	lacC	2.7.1.144	-	G	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HHOLCGFJ_02783	3.03e-118	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HHOLCGFJ_02785	4.79e-101	-	-	-	-	-	-	-	-
HHOLCGFJ_02786	2.67e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HHOLCGFJ_02787	1.4e-179	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HHOLCGFJ_02788	0.0	malP	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_02789	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHOLCGFJ_02791	0.0	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HHOLCGFJ_02792	9.39e-192	ugpE3	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02793	1.22e-219	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02794	1.27e-314	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02795	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_02796	5.84e-172	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HHOLCGFJ_02797	0.0	-	-	-	G	-	-	-	beta-fructofuranosidase activity
HHOLCGFJ_02799	3.29e-162	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HHOLCGFJ_02800	0.0	-	-	-	M	-	-	-	Belongs to the BCCT transporter (TC 2.A.15) family
HHOLCGFJ_02802	2.89e-70	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HHOLCGFJ_02803	7.35e-83	-	-	-	P	-	-	-	Bacterial extracellular solute-binding protein
HHOLCGFJ_02804	9.23e-161	-	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHOLCGFJ_02805	2.46e-255	-	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02806	7.29e-158	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02807	1.53e-135	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
HHOLCGFJ_02808	2.32e-22	-	-	-	G	-	-	-	PTS system, Lactose/Cellobiose specific IIB subunit
HHOLCGFJ_02809	8.06e-87	-	-	-	GKT	-	-	-	PRD domain
HHOLCGFJ_02810	1.82e-102	-	-	-	S	-	-	-	yiaA/B two helix domain
HHOLCGFJ_02811	4.81e-226	-	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Bacterial fructose-1,6-bisphosphatase, glpX-encoded
HHOLCGFJ_02812	4.34e-145	-	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HHOLCGFJ_02813	3.89e-241	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HHOLCGFJ_02814	6.17e-104	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
HHOLCGFJ_02815	1.08e-172	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HHOLCGFJ_02816	1.32e-172	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_02817	5.56e-270	-	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HHOLCGFJ_02818	1.12e-303	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HHOLCGFJ_02819	7.92e-74	-	-	-	S	ko:K07068	-	ko00000	DUF35 OB-fold domain, acyl-CoA-associated
HHOLCGFJ_02820	1.2e-263	-	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Thiolase, C-terminal domain
HHOLCGFJ_02821	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHOLCGFJ_02822	2.25e-118	-	-	-	S	-	-	-	DNA-binding protein with PD1-like DNA-binding motif
HHOLCGFJ_02823	9.01e-179	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HHOLCGFJ_02824	9.26e-278	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
HHOLCGFJ_02825	1.34e-109	-	-	-	G	ko:K11689	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite ATP-independent periplasmic transporters, DctQ component
HHOLCGFJ_02826	3.49e-246	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HHOLCGFJ_02827	5.17e-174	-	-	-	K	ko:K19333	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_02828	8.09e-260	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HHOLCGFJ_02831	2.58e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HHOLCGFJ_02832	5.85e-225	-	-	-	P	ko:K07217	-	ko00000	Catalase
HHOLCGFJ_02833	2.88e-217	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HHOLCGFJ_02834	0.0	-	-	-	F	-	-	-	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HHOLCGFJ_02835	8.86e-78	ydeP9	-	-	K	-	-	-	HxlR-like helix-turn-helix
HHOLCGFJ_02836	1.53e-211	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
HHOLCGFJ_02837	3.83e-199	ycnC	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02838	3.19e-264	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HHOLCGFJ_02839	8.16e-38	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HHOLCGFJ_02840	4.75e-96	-	-	-	-	-	-	-	-
HHOLCGFJ_02842	1.42e-47	-	-	-	-	-	-	-	-
HHOLCGFJ_02843	2.79e-134	-	-	-	S	-	-	-	Putative adhesin
HHOLCGFJ_02844	7.96e-158	-	-	-	S	-	-	-	ABC-2 family transporter protein
HHOLCGFJ_02845	3.21e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_02846	2.92e-171	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_02847	1.1e-256	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_02848	3.54e-199	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHOLCGFJ_02849	8.99e-167	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HHOLCGFJ_02850	1.99e-260	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HHOLCGFJ_02851	1.68e-177	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HHOLCGFJ_02852	0.0	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_02853	0.0	sfuB	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02854	2.8e-255	fbpC	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHOLCGFJ_02855	6.46e-242	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02857	6.2e-114	-	-	-	-	-	-	-	-
HHOLCGFJ_02858	1.21e-288	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
HHOLCGFJ_02859	1.26e-286	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
HHOLCGFJ_02860	5.04e-308	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HHOLCGFJ_02861	9.96e-287	-	-	-	E	-	-	-	Peptidase family M28
HHOLCGFJ_02862	1.42e-247	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_02863	1.3e-236	-	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_02864	1.12e-214	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HHOLCGFJ_02865	4.29e-202	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02866	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HHOLCGFJ_02868	8.88e-213	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02869	7.04e-207	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HHOLCGFJ_02870	1.41e-267	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HHOLCGFJ_02871	2.88e-69	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HHOLCGFJ_02872	2.68e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HHOLCGFJ_02873	5e-292	celD	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHOLCGFJ_02874	3.04e-59	-	-	-	-	-	-	-	-
HHOLCGFJ_02875	2.09e-315	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHOLCGFJ_02876	2.18e-178	-	-	-	S	-	-	-	CAAX protease self-immunity
HHOLCGFJ_02877	2.28e-113	-	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HHOLCGFJ_02878	0.0	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HHOLCGFJ_02883	0.0	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HHOLCGFJ_02886	2.13e-92	ytcD	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02887	2.78e-136	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HHOLCGFJ_02888	1.71e-144	-	-	-	K	-	-	-	intracellular protease amidase
HHOLCGFJ_02890	2.24e-31	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HHOLCGFJ_02892	1.32e-307	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHOLCGFJ_02893	9.43e-176	-	5.1.3.6	-	GM	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Male sterility protein
HHOLCGFJ_02894	1.27e-174	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HHOLCGFJ_02895	2.32e-13	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HHOLCGFJ_02896	1.73e-88	rfbP	-	-	M	ko:K19428	-	ko00000,ko01000	Bacterial sugar transferase
HHOLCGFJ_02897	1.74e-134	-	-	-	M	-	-	-	COG0438 Glycosyltransferase
HHOLCGFJ_02898	7.11e-104	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HHOLCGFJ_02900	1.56e-106	-	-	-	M	-	-	-	Glycosyl transferases group 1
HHOLCGFJ_02901	1.93e-22	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HHOLCGFJ_02902	9.58e-105	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HHOLCGFJ_02903	3.27e-302	pglF	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HHOLCGFJ_02904	2.7e-201	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HHOLCGFJ_02905	4.18e-191	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHOLCGFJ_02908	1.61e-254	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HHOLCGFJ_02909	1.04e-271	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HHOLCGFJ_02910	6.22e-245	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HHOLCGFJ_02911	0.0	gerAA	-	-	EG	ko:K06288,ko:K06310	-	ko00000	Spore germination protein
HHOLCGFJ_02912	4.83e-256	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HHOLCGFJ_02913	3.18e-133	-	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HHOLCGFJ_02914	2.05e-104	-	-	-	S	-	-	-	Bacterial PH domain
HHOLCGFJ_02915	2.38e-170	ycdF	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Short-chain dehydrogenase reductase sdr
HHOLCGFJ_02916	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HHOLCGFJ_02917	1.83e-156	mdmC1	-	-	S	-	-	-	O-methyltransferase
HHOLCGFJ_02918	4.05e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HHOLCGFJ_02919	2.76e-59	sdpR	-	-	K	-	-	-	transcriptional
HHOLCGFJ_02920	2.82e-147	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HHOLCGFJ_02921	4.03e-184	-	-	-	G	-	-	-	Phosphoenolpyruvate phosphomutase
HHOLCGFJ_02922	7.57e-207	-	-	-	E	-	-	-	Glyoxalase-like domain
HHOLCGFJ_02923	2.37e-236	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLCGFJ_02924	2.58e-178	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHOLCGFJ_02925	1.27e-165	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HHOLCGFJ_02927	2.43e-151	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
HHOLCGFJ_02928	1.85e-199	-	-	-	K	ko:K13572	-	ko00000,ko03051	transcriptional regulator
HHOLCGFJ_02929	1.63e-195	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HHOLCGFJ_02930	6.72e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_02931	1.1e-180	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HHOLCGFJ_02932	2.94e-237	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
HHOLCGFJ_02934	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HHOLCGFJ_02936	1.18e-293	-	-	-	S	-	-	-	Putative esterase
HHOLCGFJ_02937	4.71e-119	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
HHOLCGFJ_02938	3.03e-63	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HHOLCGFJ_02939	2.41e-184	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
HHOLCGFJ_02941	2.3e-277	-	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HHOLCGFJ_02942	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HHOLCGFJ_02943	0.0	-	-	-	S	-	-	-	Membrane
HHOLCGFJ_02944	6.77e-77	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HHOLCGFJ_02945	1.71e-233	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HHOLCGFJ_02946	1.92e-113	-	-	-	S	-	-	-	OHCU decarboxylase
HHOLCGFJ_02947	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HHOLCGFJ_02948	4.68e-300	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHOLCGFJ_02949	3.62e-310	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HHOLCGFJ_02950	1.63e-119	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HHOLCGFJ_02951	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HHOLCGFJ_02952	9.96e-213	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HHOLCGFJ_02953	5.06e-137	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HHOLCGFJ_02954	2.93e-235	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HHOLCGFJ_02955	5.72e-238	-	-	-	P	-	-	-	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HHOLCGFJ_02956	9.24e-188	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02957	3.25e-181	-	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HHOLCGFJ_02958	9.37e-241	-	-	-	P	-	-	-	NMT1-like family
HHOLCGFJ_02959	8.27e-192	-	-	-	P	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02960	1.96e-177	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HHOLCGFJ_02961	0.0	fhuB5	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_02962	6.15e-235	cbrA5	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Ferrichrome ABC transporter substrate-binding protein
HHOLCGFJ_02963	7.89e-91	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HHOLCGFJ_02964	9.11e-106	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HHOLCGFJ_02965	1.2e-105	-	-	-	S	-	-	-	ASCH
HHOLCGFJ_02966	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HHOLCGFJ_02967	1.44e-197	-	-	-	I	-	-	-	Domain of unknown function (DUF1932)
HHOLCGFJ_02968	1.7e-199	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HHOLCGFJ_02969	4.34e-151	-	4.1.3.17	-	H	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	ko00000,ko00001,ko01000	Methyltransferase
HHOLCGFJ_02970	3.3e-43	-	-	-	-	-	-	-	-
HHOLCGFJ_02971	6.08e-309	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
HHOLCGFJ_02972	1.37e-160	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHOLCGFJ_02973	5.68e-233	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_02974	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_02975	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HHOLCGFJ_02976	5.48e-236	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HHOLCGFJ_02977	5.93e-149	ydgI	-	-	C	-	-	-	nitroreductase
HHOLCGFJ_02978	6.26e-80	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHOLCGFJ_02979	7.41e-177	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HHOLCGFJ_02980	1.3e-266	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HHOLCGFJ_02981	3.73e-240	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HHOLCGFJ_02982	2.06e-177	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HHOLCGFJ_02983	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_02984	3.11e-219	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02985	2.08e-205	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_02986	2.41e-177	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHOLCGFJ_02987	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HHOLCGFJ_02989	2.93e-108	-	-	-	-	-	-	-	-
HHOLCGFJ_02990	0.0	gltD	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HHOLCGFJ_02991	1.91e-299	preA	1.3.1.1	-	CF	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	dihydroorotate dehydrogenase
HHOLCGFJ_02992	0.0	hydA	3.5.2.2	-	F	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Amidohydrolase family
HHOLCGFJ_02994	1.64e-302	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHOLCGFJ_02995	0.0	-	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHOLCGFJ_02996	1.99e-95	-	-	-	F	-	-	-	PFAM AIG2 family protein
HHOLCGFJ_02997	6.05e-47	-	-	-	S	-	-	-	Integral membrane protein
HHOLCGFJ_02998	1.8e-279	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HHOLCGFJ_02999	0.0	-	-	-	S	-	-	-	Hypothetical glycosyl hydrolase 6
HHOLCGFJ_03000	1.19e-282	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
HHOLCGFJ_03001	1.89e-162	-	-	-	G	-	-	-	ABC transporter permease
HHOLCGFJ_03002	4.59e-188	-	-	-	G	-	-	-	ABC-type polysaccharide transport system, permease component
HHOLCGFJ_03003	0.0	-	-	-	G	-	-	-	beta-galactosidase
HHOLCGFJ_03004	6.09e-296	-	-	-	S	-	-	-	Hypothetical glycosyl hydrolase 6
HHOLCGFJ_03005	1.68e-137	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	3-hydroxyisobutyrate dehydrogenase
HHOLCGFJ_03008	7.21e-226	-	-	-	S	-	-	-	Tetratricopeptide repeat
HHOLCGFJ_03009	0.0	-	-	-	T	-	-	-	Domain present in phytochromes and cGMP-specific phosphodiesterases.
HHOLCGFJ_03010	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHOLCGFJ_03011	1.11e-202	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HHOLCGFJ_03012	3.64e-178	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
HHOLCGFJ_03013	4.54e-95	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
HHOLCGFJ_03014	1.06e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HHOLCGFJ_03015	3.66e-157	epsB	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HHOLCGFJ_03016	1.78e-149	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HHOLCGFJ_03017	2.99e-219	tagU	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HHOLCGFJ_03018	3.78e-107	-	-	-	S	-	-	-	Tetratrico peptide repeat
HHOLCGFJ_03019	3.16e-112	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
HHOLCGFJ_03020	4.6e-102	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HHOLCGFJ_03021	2.87e-287	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HHOLCGFJ_03022	6.27e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HHOLCGFJ_03023	1.21e-215	tagU	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HHOLCGFJ_03024	2.02e-61	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HHOLCGFJ_03025	1.82e-296	-	-	-	-	-	-	-	-
HHOLCGFJ_03026	2.96e-305	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHOLCGFJ_03027	2.71e-298	lytE	-	-	M	-	-	-	NlpC/P60 family
HHOLCGFJ_03028	1.2e-195	-	-	-	Q	-	-	-	N-acetyltransferase
HHOLCGFJ_03029	3.37e-115	yisT	-	-	S	-	-	-	DinB family
HHOLCGFJ_03030	7.16e-127	-	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHOLCGFJ_03031	0.0	pip	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HHOLCGFJ_03032	1.09e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHOLCGFJ_03033	3.57e-188	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
HHOLCGFJ_03034	1.52e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HHOLCGFJ_03035	1.53e-30	-	-	-	S	ko:K06308	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HHOLCGFJ_03036	8.27e-191	-	-	-	S	ko:K06308	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HHOLCGFJ_03037	1.62e-255	-	-	-	E	-	-	-	Spore germination protein
HHOLCGFJ_03038	0.0	-	-	-	P	-	-	-	Spore gernimation protein GerA
HHOLCGFJ_03039	4.62e-81	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HHOLCGFJ_03040	3.39e-182	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HHOLCGFJ_03041	2.58e-183	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HHOLCGFJ_03042	1.9e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HHOLCGFJ_03043	1.68e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HHOLCGFJ_03044	2.02e-63	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HHOLCGFJ_03045	1.25e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HHOLCGFJ_03046	1.07e-181	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HHOLCGFJ_03047	1.78e-242	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HHOLCGFJ_03048	1.92e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHOLCGFJ_03049	1.66e-21	ywmB	-	-	S	-	-	-	TATA-box binding
HHOLCGFJ_03050	2.09e-81	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HHOLCGFJ_03051	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHOLCGFJ_03052	3.39e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHOLCGFJ_03053	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHOLCGFJ_03054	7.09e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHOLCGFJ_03055	2.37e-47	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHOLCGFJ_03056	2.78e-28	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHOLCGFJ_03057	3.41e-170	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HHOLCGFJ_03058	1.25e-10	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase I chain
HHOLCGFJ_03059	1.61e-44	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
HHOLCGFJ_03060	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HHOLCGFJ_03061	1.1e-117	panZ	-	-	K	-	-	-	-acetyltransferase
HHOLCGFJ_03062	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHOLCGFJ_03063	1.07e-302	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHOLCGFJ_03064	2.21e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HHOLCGFJ_03065	3.9e-105	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HHOLCGFJ_03066	8.28e-248	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Chemotaxis
HHOLCGFJ_03067	4.11e-95	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHOLCGFJ_03068	3.39e-121	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HHOLCGFJ_03069	4.54e-77	-	-	-	S	-	-	-	Regulator of ribonuclease activity B
HHOLCGFJ_03070	9.58e-235	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHOLCGFJ_03071	1.36e-96	ywlB	1.20.4.1, 2.3.1.1	-	E	ko:K00537,ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetyltransferase family. ArgA subfamily
HHOLCGFJ_03072	7.81e-148	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HHOLCGFJ_03073	2.64e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHOLCGFJ_03074	3.12e-232	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHOLCGFJ_03075	0.0	cdr	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HHOLCGFJ_03076	1.19e-97	-	-	-	-	-	-	-	-
HHOLCGFJ_03077	1.88e-142	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HHOLCGFJ_03078	2.08e-54	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HHOLCGFJ_03079	2.94e-300	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HHOLCGFJ_03080	2.21e-228	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HHOLCGFJ_03081	2e-285	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHOLCGFJ_03082	2.81e-149	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHOLCGFJ_03083	3.32e-206	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HHOLCGFJ_03084	1.27e-78	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
HHOLCGFJ_03085	4.35e-120	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HHOLCGFJ_03086	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHOLCGFJ_03087	6.82e-95	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHOLCGFJ_03088	1.83e-141	kstR2_2	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_03089	1.15e-262	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HHOLCGFJ_03090	5.06e-199	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HHOLCGFJ_03091	2.8e-277	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
HHOLCGFJ_03092	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HHOLCGFJ_03093	8.42e-281	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HHOLCGFJ_03094	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HHOLCGFJ_03095	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HHOLCGFJ_03096	2.43e-264	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HHOLCGFJ_03097	1.19e-296	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HHOLCGFJ_03098	9.24e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHOLCGFJ_03099	4.68e-234	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HHOLCGFJ_03101	0.0	-	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HHOLCGFJ_03102	7.54e-68	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_03103	3.42e-29	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HHOLCGFJ_03105	1.94e-47	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HHOLCGFJ_03106	2.18e-109	-	-	-	-	-	-	-	-
HHOLCGFJ_03107	7.45e-317	-	-	-	P	ko:K14445	-	ko00000,ko02000	Sodium:sulfate symporter transmembrane region
HHOLCGFJ_03108	5.31e-277	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
HHOLCGFJ_03109	1.19e-173	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_03110	8.23e-147	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HHOLCGFJ_03111	1.72e-72	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
HHOLCGFJ_03112	3.33e-133	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_03113	1.06e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HHOLCGFJ_03114	2.83e-150	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HHOLCGFJ_03115	9.88e-302	ywoF	-	-	P	-	-	-	Right handed beta helix region
HHOLCGFJ_03116	1.75e-113	mutT	3.6.1.13, 3.6.1.55	-	L	ko:K01515,ko:K03574	ko00230,map00230	ko00000,ko00001,ko01000,ko03400	nUDIX hydrolase
HHOLCGFJ_03117	4.33e-41	-	-	-	S	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHOLCGFJ_03118	5.28e-146	-	-	-	M	-	-	-	Peptidase family M23
HHOLCGFJ_03120	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
HHOLCGFJ_03121	4.46e-192	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03122	1.78e-209	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03123	3.12e-277	-	3.2.1.180	GH88	O	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HHOLCGFJ_03124	2.47e-220	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_03125	1.42e-291	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_03126	6.01e-270	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_03127	7.62e-133	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_03128	2.32e-184	inoDHR	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHOLCGFJ_03129	3.44e-199	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03130	3.93e-220	ugpA7	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03131	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
HHOLCGFJ_03132	2.45e-268	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_03133	5.46e-181	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHOLCGFJ_03134	8.28e-222	-	-	-	K	-	-	-	Cupin domain
HHOLCGFJ_03135	1.86e-243	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HHOLCGFJ_03136	8.79e-86	-	-	-	S	-	-	-	Protein of unknown function, DUF393
HHOLCGFJ_03137	3.31e-206	yfhB	-	-	S	-	-	-	PhzF family
HHOLCGFJ_03138	5.71e-132	-	-	-	V	-	-	-	Beta-lactamase
HHOLCGFJ_03139	8.62e-120	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHOLCGFJ_03140	0.0	-	-	-	E	-	-	-	Aminotransferase class-V
HHOLCGFJ_03141	0.0	-	-	-	M	-	-	-	Sulfatase
HHOLCGFJ_03142	3.39e-91	-	-	-	E	ko:K07032	-	ko00000	lactoylglutathione lyase activity
HHOLCGFJ_03143	4.69e-200	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HHOLCGFJ_03145	1.72e-213	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HHOLCGFJ_03146	4.83e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HHOLCGFJ_03147	1.45e-45	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HHOLCGFJ_03148	3.03e-190	araQ	-	-	P	ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHOLCGFJ_03149	2.95e-206	-	-	-	G	ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03150	8.98e-311	-	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLCGFJ_03151	1.11e-66	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HHOLCGFJ_03152	3.11e-153	-	-	-	E	-	-	-	AzlC protein
HHOLCGFJ_03153	7.81e-128	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_03154	1.58e-116	M1-753	-	-	M	-	-	-	FR47-like protein
HHOLCGFJ_03155	1.69e-184	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase domain
HHOLCGFJ_03157	5.27e-49	ydaS	-	-	S	-	-	-	membrane
HHOLCGFJ_03158	4.11e-123	ywmF	-	-	S	-	-	-	Peptidase M50
HHOLCGFJ_03159	3.79e-309	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HHOLCGFJ_03160	2.15e-153	ypgQ	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HHOLCGFJ_03161	2.53e-38	-	-	-	-	-	-	-	-
HHOLCGFJ_03162	0.0	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase
HHOLCGFJ_03163	1.07e-263	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HHOLCGFJ_03164	1.33e-279	-	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
HHOLCGFJ_03165	3.06e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_03166	5.43e-165	-	-	-	K	-	-	-	acetyltransferase
HHOLCGFJ_03167	1.77e-108	-	-	-	S	ko:K06385	-	ko00000	Stage II sporulation protein P (SpoIIP)
HHOLCGFJ_03168	2.01e-211	-	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein kinase domain
HHOLCGFJ_03169	1.68e-76	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
HHOLCGFJ_03170	3.43e-234	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HHOLCGFJ_03171	4.61e-125	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HHOLCGFJ_03172	2.61e-122	-	-	-	-	-	-	-	-
HHOLCGFJ_03174	6.13e-233	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HHOLCGFJ_03175	5.73e-301	-	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_03176	0.0	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HHOLCGFJ_03177	1.02e-285	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHOLCGFJ_03178	0.0	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HHOLCGFJ_03179	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HHOLCGFJ_03180	0.0	-	-	-	T	-	-	-	COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HHOLCGFJ_03181	2.7e-279	-	-	-	G	-	-	-	Transmembrane secretion effector
HHOLCGFJ_03182	6.04e-250	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_03183	1.11e-134	desR	-	-	K	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HHOLCGFJ_03184	9.44e-153	-	-	-	-	-	-	-	-
HHOLCGFJ_03185	2.24e-199	-	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
HHOLCGFJ_03186	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HHOLCGFJ_03187	7.39e-224	-	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HHOLCGFJ_03188	2.03e-130	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HHOLCGFJ_03189	2.6e-92	-	-	-	-	-	-	-	-
HHOLCGFJ_03190	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HHOLCGFJ_03191	1.36e-265	gatD	1.1.1.14, 1.1.1.251	-	C	ko:K00008,ko:K00094	ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
HHOLCGFJ_03192	1.15e-29	-	-	-	-	-	-	-	-
HHOLCGFJ_03193	4.25e-248	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHOLCGFJ_03194	6.01e-287	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3775 Phosphotransferase system, galactitol-specific IIC component
HHOLCGFJ_03195	3.67e-57	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HHOLCGFJ_03196	7.83e-104	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHOLCGFJ_03197	0.0	-	-	-	GKT	-	-	-	COG3711 Transcriptional antiterminator
HHOLCGFJ_03198	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HHOLCGFJ_03199	1.97e-255	-	-	-	-	-	-	-	-
HHOLCGFJ_03200	7.47e-141	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HHOLCGFJ_03201	6.83e-225	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HHOLCGFJ_03202	1.85e-144	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHOLCGFJ_03203	7.67e-124	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HHOLCGFJ_03204	1.38e-264	siaT_3	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HHOLCGFJ_03205	9.62e-111	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HHOLCGFJ_03206	6.9e-234	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HHOLCGFJ_03207	4.86e-234	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HHOLCGFJ_03208	4.89e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HHOLCGFJ_03209	1.38e-97	-	-	-	-	-	-	-	-
HHOLCGFJ_03210	2.71e-102	-	-	-	-	-	-	-	-
HHOLCGFJ_03211	5.89e-257	ysdC_3	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	M42 glutamyl aminopeptidase
HHOLCGFJ_03212	7.46e-59	M1-485	-	-	S	-	-	-	Membrane
HHOLCGFJ_03213	2.07e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HHOLCGFJ_03214	6.17e-241	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HHOLCGFJ_03215	6.61e-187	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HHOLCGFJ_03216	7.44e-186	-	-	-	S	ko:K06976	-	ko00000	GNAT acetyltransferase
HHOLCGFJ_03217	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HHOLCGFJ_03218	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HHOLCGFJ_03219	3.97e-35	-	-	-	-	-	-	-	-
HHOLCGFJ_03220	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HHOLCGFJ_03221	6.34e-178	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HHOLCGFJ_03222	3.63e-143	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HHOLCGFJ_03223	3.83e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHOLCGFJ_03224	4.22e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_03225	7.66e-163	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HHOLCGFJ_03226	1.67e-135	-	-	-	-	-	-	-	-
HHOLCGFJ_03227	2.51e-06	liaI	-	-	-	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	-
HHOLCGFJ_03228	1.01e-48	-	-	-	-	-	-	-	-
HHOLCGFJ_03229	4.25e-151	-	-	-	S	-	-	-	Cupin
HHOLCGFJ_03230	0.0	-	-	-	M	-	-	-	glycoside hydrolase family 81
HHOLCGFJ_03231	7.61e-247	cytR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HHOLCGFJ_03232	3.83e-165	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HHOLCGFJ_03233	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHOLCGFJ_03234	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHOLCGFJ_03235	7.97e-222	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_03236	1.1e-228	-	-	-	K	-	-	-	WYL domain
HHOLCGFJ_03237	6.68e-147	-	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HHOLCGFJ_03238	1.5e-197	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHOLCGFJ_03239	5.01e-202	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HHOLCGFJ_03240	8.37e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HHOLCGFJ_03241	5.77e-214	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_03242	0.0	gdhA	1.4.1.2, 1.4.1.4	-	E	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HHOLCGFJ_03243	6.85e-179	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHOLCGFJ_03244	2.03e-223	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLCGFJ_03245	1.14e-259	-	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HHOLCGFJ_03246	1.33e-176	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HHOLCGFJ_03247	1.29e-76	-	-	-	S	-	-	-	Dinitrogenase iron-molybdenum cofactor
HHOLCGFJ_03248	1.53e-315	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHOLCGFJ_03249	4.27e-120	ssuE	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
HHOLCGFJ_03250	1.3e-209	ytlI3	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HHOLCGFJ_03251	6.99e-112	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HHOLCGFJ_03252	1.6e-148	-	-	-	S	-	-	-	membrane
HHOLCGFJ_03253	1.03e-37	-	-	-	S	-	-	-	spore protein
HHOLCGFJ_03254	4.37e-39	-	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HHOLCGFJ_03255	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHOLCGFJ_03257	7.78e-202	yerO	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_03258	1.38e-165	-	-	-	-	-	-	-	-
HHOLCGFJ_03259	3.75e-210	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HHOLCGFJ_03260	8.89e-80	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HHOLCGFJ_03261	9.53e-147	-	-	-	Q	-	-	-	Methyltransferase domain
HHOLCGFJ_03262	8.33e-186	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HHOLCGFJ_03263	2.54e-10	-	-	-	-	-	-	-	-
HHOLCGFJ_03264	5.94e-285	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHOLCGFJ_03265	2.02e-215	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HHOLCGFJ_03266	1.18e-222	-	-	-	P	ko:K07217	-	ko00000	Catalase
HHOLCGFJ_03267	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2254)
HHOLCGFJ_03268	1.03e-208	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycine betaine ABC transporter
HHOLCGFJ_03269	2.75e-306	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HHOLCGFJ_03270	1.39e-182	srtB	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HHOLCGFJ_03271	1.27e-174	fepC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_03272	1.16e-217	fhuB11	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_03273	4.04e-210	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLCGFJ_03274	0.0	-	-	-	M	-	-	-	Cell surface protein
HHOLCGFJ_03275	1.96e-156	isdC	-	-	M	-	-	-	NEAr Transporter domain
HHOLCGFJ_03276	2.94e-71	isdG	1.14.99.48	-	C	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
HHOLCGFJ_03277	1.16e-221	fhuG7	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_03278	2.98e-219	fhuD11	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HHOLCGFJ_03279	1.52e-286	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHOLCGFJ_03280	1.29e-190	-	-	-	S	-	-	-	Methyltransferase domain
HHOLCGFJ_03281	1.52e-144	-	-	-	K	-	-	-	Bacterial transcriptional repressor C-terminal
HHOLCGFJ_03282	0.0	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HHOLCGFJ_03283	4.3e-295	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HHOLCGFJ_03284	5.26e-163	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HHOLCGFJ_03285	1.4e-199	gltR3	-	-	K	-	-	-	LysR substrate binding domain
HHOLCGFJ_03286	1.69e-232	-	3.8.1.3	-	S	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
HHOLCGFJ_03287	1.58e-200	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
HHOLCGFJ_03288	7.51e-238	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HHOLCGFJ_03289	5.53e-242	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_03290	1.57e-189	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03291	1.48e-218	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03292	4.41e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_03293	5.15e-289	-	-	-	GK	-	-	-	ROK family
HHOLCGFJ_03294	1.3e-281	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HHOLCGFJ_03295	1.1e-86	yqiX	-	-	S	-	-	-	YolD-like protein
HHOLCGFJ_03297	3.02e-06	sda	-	-	S	ko:K06371	-	ko00000	sporulation
HHOLCGFJ_03298	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
HHOLCGFJ_03299	2.64e-63	-	-	-	-	-	-	-	-
HHOLCGFJ_03300	3.14e-113	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HHOLCGFJ_03301	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HHOLCGFJ_03302	0.0	-	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase
HHOLCGFJ_03303	7.92e-253	dctP	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHOLCGFJ_03304	0.0	-	-	-	-	-	-	-	-
HHOLCGFJ_03305	2.23e-218	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HHOLCGFJ_03306	1.28e-227	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HHOLCGFJ_03307	1.25e-159	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HHOLCGFJ_03310	9.21e-212	-	-	-	V	-	-	-	VanW like protein
HHOLCGFJ_03311	1.99e-124	-	-	-	V	-	-	-	(ABC) transporter
HHOLCGFJ_03312	2.06e-61	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
HHOLCGFJ_03313	2.12e-155	yqeB	-	-	-	-	-	-	-
HHOLCGFJ_03314	1.72e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_03315	1.1e-196	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHOLCGFJ_03316	0.0	-	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHOLCGFJ_03317	5.31e-115	-	1.8.5.2	-	S	ko:K16937	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	DoxX
HHOLCGFJ_03318	4.27e-33	-	-	-	-	-	-	-	-
HHOLCGFJ_03319	3.04e-80	-	-	-	-	-	-	-	-
HHOLCGFJ_03320	3.76e-142	-	-	-	K	ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HHOLCGFJ_03322	1.6e-198	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HHOLCGFJ_03323	2.74e-240	-	-	-	G	-	-	-	Xylose isomerase
HHOLCGFJ_03324	3.93e-184	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03325	2.95e-212	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03326	9.09e-301	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_03327	2.33e-237	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_03328	4.54e-241	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HHOLCGFJ_03329	7.67e-80	-	-	-	S	-	-	-	Ketosteroid isomerase-related protein
HHOLCGFJ_03330	4.33e-189	-	-	-	K	-	-	-	Helix-turn-helix domain
HHOLCGFJ_03331	8.71e-232	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHOLCGFJ_03332	2.61e-198	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
HHOLCGFJ_03333	1.52e-241	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HHOLCGFJ_03334	2.22e-311	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HHOLCGFJ_03335	2.47e-178	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HHOLCGFJ_03336	1.74e-201	-	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
HHOLCGFJ_03337	1.56e-161	-	-	-	KT	-	-	-	Forkhead associated domain
HHOLCGFJ_03338	2.9e-312	amaB_2	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHOLCGFJ_03339	3.08e-204	yuiI	-	-	S	ko:K07017	-	ko00000	Putative esterase
HHOLCGFJ_03340	1.06e-236	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_03341	8.75e-237	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_03342	1.37e-224	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HHOLCGFJ_03343	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HHOLCGFJ_03345	1.5e-230	ectD	1.14.11.55	-	Q	ko:K10674	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Phytanoyl-CoA dioxygenase (PhyH)
HHOLCGFJ_03346	9.05e-258	-	-	-	-	-	-	-	-
HHOLCGFJ_03347	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HHOLCGFJ_03348	5.78e-247	gerKB	-	-	E	-	-	-	Spore germination protein
HHOLCGFJ_03349	1.92e-262	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
HHOLCGFJ_03350	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HHOLCGFJ_03351	6.09e-175	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_03352	2.29e-299	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_03353	3.71e-155	msmF3	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03354	6.07e-186	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HHOLCGFJ_03355	0.0	-	-	-	S	-	-	-	Chlorophyllase enzyme
HHOLCGFJ_03356	1.56e-82	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHOLCGFJ_03357	0.0	-	-	-	GKT	-	-	-	Mga helix-turn-helix domain
HHOLCGFJ_03358	9.8e-234	-	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHOLCGFJ_03359	2.25e-60	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
HHOLCGFJ_03360	4.42e-274	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
HHOLCGFJ_03361	3.3e-200	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HHOLCGFJ_03362	7.71e-133	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HHOLCGFJ_03363	3.01e-09	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HHOLCGFJ_03364	1.16e-203	-	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Ribosomal RNA adenine dimethylases
HHOLCGFJ_03365	6.41e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF4260)
HHOLCGFJ_03366	8.65e-92	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HHOLCGFJ_03367	1.83e-257	-	6.3.5.5	-	S	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	ATP-grasp domain
HHOLCGFJ_03368	1.86e-267	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HHOLCGFJ_03369	1.15e-130	-	-	-	S	-	-	-	DinB superfamily
HHOLCGFJ_03371	3.45e-165	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HHOLCGFJ_03372	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HHOLCGFJ_03373	2.6e-301	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HHOLCGFJ_03374	3.52e-191	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HHOLCGFJ_03375	7.41e-315	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HHOLCGFJ_03376	4.2e-303	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HHOLCGFJ_03377	4.52e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_03378	0.0	-	-	-	-	-	-	-	-
HHOLCGFJ_03379	0.0	-	-	-	-	-	-	-	-
HHOLCGFJ_03380	5.87e-196	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HHOLCGFJ_03381	4.15e-191	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_03382	1.04e-141	-	-	-	S	-	-	-	ABC-2 family transporter protein
HHOLCGFJ_03383	1.19e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HHOLCGFJ_03384	1.84e-235	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_03385	5.72e-241	-	-	-	E	-	-	-	Amidinotransferase
HHOLCGFJ_03386	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
HHOLCGFJ_03387	3.97e-174	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HHOLCGFJ_03388	5.64e-254	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HHOLCGFJ_03389	5.54e-286	-	-	-	S	-	-	-	Erythromycin esterase
HHOLCGFJ_03390	2.46e-118	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_03391	1.27e-231	-	-	-	S	-	-	-	Choline/ethanolamine kinase
HHOLCGFJ_03392	6.66e-72	-	-	-	-	-	-	-	-
HHOLCGFJ_03393	0.0	-	-	-	-	-	-	-	-
HHOLCGFJ_03394	5.02e-150	-	-	-	-	-	-	-	-
HHOLCGFJ_03395	3.34e-80	-	-	-	K	-	-	-	MerR, DNA binding
HHOLCGFJ_03396	3.03e-193	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HHOLCGFJ_03397	1.95e-90	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_03398	4.03e-99	-	-	-	-	-	-	-	-
HHOLCGFJ_03400	8.89e-156	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HHOLCGFJ_03401	2.93e-85	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHOLCGFJ_03402	1.93e-77	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHOLCGFJ_03403	1.28e-274	-	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HHOLCGFJ_03406	4.71e-239	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HHOLCGFJ_03407	1.15e-109	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HHOLCGFJ_03408	1.44e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HHOLCGFJ_03409	2.21e-114	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HHOLCGFJ_03410	2.49e-232	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHOLCGFJ_03411	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HHOLCGFJ_03412	6.15e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHOLCGFJ_03413	7.3e-34	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HHOLCGFJ_03414	2.86e-179	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHOLCGFJ_03415	2.61e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHOLCGFJ_03416	3.92e-143	metP_2	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HHOLCGFJ_03417	1.57e-194	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
HHOLCGFJ_03418	1.64e-263	gldA	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HHOLCGFJ_03420	1.16e-153	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HHOLCGFJ_03421	7.46e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHOLCGFJ_03422	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHOLCGFJ_03423	0.0	-	-	-	G	-	-	-	Mga helix-turn-helix domain
HHOLCGFJ_03424	2.88e-96	-	2.7.1.194	-	GT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHOLCGFJ_03425	5.5e-56	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
HHOLCGFJ_03426	3.06e-283	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
HHOLCGFJ_03427	3.13e-170	-	-	-	S	-	-	-	carbohydrate derivative metabolic process
HHOLCGFJ_03428	1.75e-158	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HHOLCGFJ_03429	2.72e-195	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHOLCGFJ_03430	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HHOLCGFJ_03431	6.01e-115	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HHOLCGFJ_03432	6.79e-135	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HHOLCGFJ_03433	1.37e-109	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HHOLCGFJ_03434	8.79e-239	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HHOLCGFJ_03435	2.77e-308	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HHOLCGFJ_03436	5.32e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HHOLCGFJ_03437	2.79e-97	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HHOLCGFJ_03438	1e-47	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HHOLCGFJ_03439	7.57e-184	nirC	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
HHOLCGFJ_03440	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HHOLCGFJ_03441	7.47e-141	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HHOLCGFJ_03442	3.52e-177	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HHOLCGFJ_03443	5.31e-115	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HHOLCGFJ_03444	4.31e-11	-	-	-	-	-	-	-	-
HHOLCGFJ_03445	6.31e-11	-	-	-	-	-	-	-	-
HHOLCGFJ_03446	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HHOLCGFJ_03447	2.15e-92	-	-	-	S	-	-	-	GtrA-like protein
HHOLCGFJ_03448	2.7e-232	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HHOLCGFJ_03449	1.89e-197	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HHOLCGFJ_03450	1.8e-185	-	-	-	-	-	-	-	-
HHOLCGFJ_03451	1.33e-191	tcyA_1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HHOLCGFJ_03452	3.11e-145	-	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03453	3.26e-153	-	-	-	E	ko:K02029,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03454	1.14e-190	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HHOLCGFJ_03455	1.06e-96	-	-	-	M	-	-	-	ArpU family transcriptional regulator
HHOLCGFJ_03456	0.0	malK	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HHOLCGFJ_03457	1.67e-160	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HHOLCGFJ_03458	1.34e-312	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
HHOLCGFJ_03459	2.12e-271	-	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HHOLCGFJ_03460	3.69e-193	-	-	-	S	-	-	-	Short C-terminal domain
HHOLCGFJ_03461	9e-94	-	-	-	-	-	-	-	-
HHOLCGFJ_03462	1.42e-101	-	-	-	-	-	-	-	-
HHOLCGFJ_03463	1.4e-244	-	-	-	D	-	-	-	Phage tail tape measure protein, TP901 family
HHOLCGFJ_03464	8.4e-176	-	-	-	S	-	-	-	Phage tail protein
HHOLCGFJ_03465	0.0	-	-	-	L	-	-	-	Phage minor structural protein
HHOLCGFJ_03467	2.31e-100	-	-	-	S	-	-	-	Bacteriophage holin family
HHOLCGFJ_03468	7.89e-153	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HHOLCGFJ_03469	5.56e-139	yfhC	-	-	C	-	-	-	nitroreductase
HHOLCGFJ_03470	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HHOLCGFJ_03471	1.15e-12	-	-	-	-	-	-	-	-
HHOLCGFJ_03473	1.07e-236	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HHOLCGFJ_03474	1.01e-129	-	-	-	CO	-	-	-	Thioredoxin
HHOLCGFJ_03475	1.87e-221	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HHOLCGFJ_03476	8.65e-275	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HHOLCGFJ_03477	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HHOLCGFJ_03478	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HHOLCGFJ_03479	1.01e-100	-	-	-	S	-	-	-	glyoxalase bleomycin resistance protein dioxygenase
HHOLCGFJ_03480	1.4e-314	-	-	-	C	-	-	-	Na+/H+ antiporter family
HHOLCGFJ_03481	8.48e-241	dapB	1.4.1.12, 1.4.1.26	-	S	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	ko00000,ko00001,ko01000	Dihydrodipicolinate reductase, N-terminus
HHOLCGFJ_03482	5.8e-219	-	-	-	K	-	-	-	LysR substrate binding domain
HHOLCGFJ_03483	1.92e-44	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
HHOLCGFJ_03485	5.08e-67	-	-	-	E	-	-	-	lactoylglutathione lyase activity
HHOLCGFJ_03486	5.96e-88	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HHOLCGFJ_03487	1.34e-85	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HHOLCGFJ_03488	8.3e-117	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_03489	4.64e-151	XK27_07680	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HHOLCGFJ_03490	3.4e-235	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HHOLCGFJ_03491	0.0	-	2.7.1.194	-	GKT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	COG3711 Transcriptional antiterminator
HHOLCGFJ_03492	1.78e-56	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HHOLCGFJ_03493	3.16e-296	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
HHOLCGFJ_03494	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHOLCGFJ_03495	1.13e-110	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HHOLCGFJ_03496	7.11e-227	dhaK	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dihydroxyacetone kinase DhaK, subunit
HHOLCGFJ_03497	4.71e-142	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HHOLCGFJ_03498	1.68e-85	-	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HHOLCGFJ_03499	3.49e-32	-	-	-	S	-	-	-	YfhD-like protein
HHOLCGFJ_03500	1.75e-277	-	-	-	G	-	-	-	Transmembrane secretion effector
HHOLCGFJ_03501	5.04e-231	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HHOLCGFJ_03502	9.43e-91	-	-	-	-	-	-	-	-
HHOLCGFJ_03503	2.96e-285	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HHOLCGFJ_03505	0.0	-	-	-	S	-	-	-	proteins of the AP superfamily
HHOLCGFJ_03506	2.96e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHOLCGFJ_03507	1.93e-191	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HHOLCGFJ_03508	4.24e-218	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HHOLCGFJ_03509	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
HHOLCGFJ_03510	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HHOLCGFJ_03512	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HHOLCGFJ_03513	4.52e-37	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_03514	4.68e-99	ygaO	-	-	-	-	-	-	-
HHOLCGFJ_03515	1.28e-132	-	-	-	Q	-	-	-	Isochorismatase family
HHOLCGFJ_03516	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HHOLCGFJ_03517	0.0	abgT_2	-	-	H	ko:K12942	-	ko00000	AbgT putative transporter family
HHOLCGFJ_03518	1.74e-291	cypA	-	-	C	ko:K15468	-	ko00000,ko01008	Cytochrome P450
HHOLCGFJ_03519	2.91e-27	-	-	-	-	-	-	-	-
HHOLCGFJ_03520	0.0	-	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HHOLCGFJ_03521	2.93e-176	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HHOLCGFJ_03522	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HHOLCGFJ_03523	3.55e-163	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HHOLCGFJ_03524	1.36e-177	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HHOLCGFJ_03525	7.06e-291	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HHOLCGFJ_03526	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HHOLCGFJ_03527	2.19e-130	-	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HHOLCGFJ_03528	1.03e-202	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Substrate binding domain of ABC-type glycine betaine transport system
HHOLCGFJ_03529	8.62e-214	-	-	-	Q	-	-	-	calcium- and calmodulin-responsive adenylate cyclase activity
HHOLCGFJ_03530	0.0	-	-	-	M	-	-	-	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HHOLCGFJ_03531	1.93e-137	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HHOLCGFJ_03532	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	transcriptional antiterminator
HHOLCGFJ_03533	0.0	lipA1	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HHOLCGFJ_03534	1.42e-146	mqnB	3.2.2.26	-	F	ko:K11783	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HHOLCGFJ_03535	2.34e-205	mqnD	-	-	S	ko:K11785	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HHOLCGFJ_03536	6.75e-138	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HHOLCGFJ_03537	5.61e-115	-	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HHOLCGFJ_03538	7.11e-174	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HHOLCGFJ_03539	6.31e-172	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_03540	2.85e-206	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HHOLCGFJ_03541	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HHOLCGFJ_03542	3.88e-152	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_03543	1.32e-169	mta	-	-	K	-	-	-	transcriptional
HHOLCGFJ_03544	3.1e-269	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HHOLCGFJ_03545	3.39e-127	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HHOLCGFJ_03548	3.86e-299	-	-	-	G	-	-	-	Major facilitator Superfamily
HHOLCGFJ_03550	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HHOLCGFJ_03551	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HHOLCGFJ_03552	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HHOLCGFJ_03553	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HHOLCGFJ_03554	9.4e-156	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HHOLCGFJ_03555	1.72e-244	-	-	-	S	ko:K07795	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter family receptor
HHOLCGFJ_03556	5.92e-97	-	-	-	S	ko:K07794	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctB family
HHOLCGFJ_03557	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
HHOLCGFJ_03558	2.22e-25	-	-	-	L	-	-	-	Initiator Replication protein
HHOLCGFJ_03559	7.15e-43	yebG	-	-	S	-	-	-	NETI protein
HHOLCGFJ_03560	6.77e-88	-	-	-	S	-	-	-	Calcium/calmodulin dependent protein kinase II association domain
HHOLCGFJ_03561	1.94e-143	-	-	-	-	-	-	-	-
HHOLCGFJ_03562	4.2e-157	-	-	-	S	-	-	-	PFAM AIG2 family protein
HHOLCGFJ_03563	1.33e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HHOLCGFJ_03564	5.38e-166	-	-	-	S	-	-	-	CAAX protease self-immunity
HHOLCGFJ_03565	3.35e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHOLCGFJ_03566	2.02e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHOLCGFJ_03567	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHOLCGFJ_03568	1.13e-164	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HHOLCGFJ_03569	5.87e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHOLCGFJ_03570	6.66e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHOLCGFJ_03571	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHOLCGFJ_03572	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHOLCGFJ_03573	2.04e-252	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HHOLCGFJ_03574	1.21e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHOLCGFJ_03575	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HHOLCGFJ_03576	1.53e-302	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HHOLCGFJ_03577	1.2e-261	-	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
HHOLCGFJ_03578	1.11e-240	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HHOLCGFJ_03579	3.4e-176	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_03580	1.33e-253	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HHOLCGFJ_03581	1.45e-296	gntT	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HHOLCGFJ_03582	5.63e-176	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_03583	1.41e-196	fhuD9	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HHOLCGFJ_03584	3.32e-119	ttr	-	-	K	-	-	-	GCN5 family acetyltransferase
HHOLCGFJ_03585	4.28e-256	-	-	-	T	-	-	-	Signal transduction histidine kinase
HHOLCGFJ_03586	3.54e-140	-	-	-	KT	-	-	-	LuxR family transcriptional regulator
HHOLCGFJ_03587	4.96e-219	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HHOLCGFJ_03588	2.73e-282	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HHOLCGFJ_03589	1.29e-238	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HHOLCGFJ_03591	2.87e-51	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
HHOLCGFJ_03592	1.35e-51	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
HHOLCGFJ_03593	1.22e-304	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HHOLCGFJ_03594	1.92e-29	-	-	-	-	-	-	-	-
HHOLCGFJ_03597	2.13e-124	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HHOLCGFJ_03598	7.21e-281	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HHOLCGFJ_03599	6.84e-190	gbuB	-	-	P	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HHOLCGFJ_03600	1.26e-217	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HHOLCGFJ_03602	2.3e-256	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HHOLCGFJ_03603	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HHOLCGFJ_03604	1.55e-66	yerC	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_03605	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HHOLCGFJ_03606	0.0	acyII	3.5.1.11	-	S	ko:K01434	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000,ko01002	Penicillin amidase
HHOLCGFJ_03607	7.93e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HHOLCGFJ_03608	5.02e-33	mepA	-	-	V	-	-	-	MATE efflux family protein
HHOLCGFJ_03610	2.97e-227	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_03611	1.16e-222	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOLCGFJ_03612	4.33e-196	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HHOLCGFJ_03613	1.16e-167	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HHOLCGFJ_03614	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HHOLCGFJ_03615	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHOLCGFJ_03616	3.07e-285	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HHOLCGFJ_03617	2.24e-261	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HHOLCGFJ_03618	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_03619	1.3e-242	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHOLCGFJ_03620	2.6e-209	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHOLCGFJ_03622	1.02e-229	-	-	-	-	-	-	-	-
HHOLCGFJ_03623	5.2e-118	yizA	-	-	S	-	-	-	DinB family
HHOLCGFJ_03624	3.39e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHOLCGFJ_03625	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHOLCGFJ_03626	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHOLCGFJ_03627	1.43e-219	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHOLCGFJ_03628	1.2e-105	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HHOLCGFJ_03629	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHOLCGFJ_03630	7.48e-133	-	-	-	-	-	-	-	-
HHOLCGFJ_03631	0.0	-	2.7.1.194	-	GKT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	COG3711 Transcriptional antiterminator
HHOLCGFJ_03632	8.46e-58	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
HHOLCGFJ_03633	2.22e-284	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
HHOLCGFJ_03634	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHOLCGFJ_03635	7.14e-180	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HHOLCGFJ_03636	6.55e-42	-	-	-	K	-	-	-	MerR family transcriptional regulator
HHOLCGFJ_03637	7.79e-316	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HHOLCGFJ_03638	0.0	-	4.2.1.82	-	EG	ko:K22396	ko00040,map00040	ko00000,ko00001,ko01000	Dehydratase family
HHOLCGFJ_03639	3.39e-180	-	-	-	K	ko:K19333	-	ko00000,ko03000	helix_turn_helix isocitrate lyase regulation
HHOLCGFJ_03640	1.12e-210	-	4.2.1.141	-	S	ko:K14259	ko00040,map00040	ko00000,ko00001,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HHOLCGFJ_03641	4.94e-213	-	4.1.2.28, 4.3.3.7	-	EM	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HHOLCGFJ_03642	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHOLCGFJ_03643	3.98e-170	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HHOLCGFJ_03644	4.17e-174	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HHOLCGFJ_03645	0.0	psaA3	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HHOLCGFJ_03646	1.94e-244	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HHOLCGFJ_03647	2.05e-231	yjiA	-	-	S	-	-	-	Cobalamin biosynthesis protein CobW
HHOLCGFJ_03648	4.06e-209	-	-	-	S	-	-	-	Alpha beta hydrolase
HHOLCGFJ_03649	1.99e-176	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HHOLCGFJ_03650	2.36e-213	-	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HHOLCGFJ_03651	1.26e-208	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_03652	7.64e-248	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HHOLCGFJ_03653	5.51e-118	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HHOLCGFJ_03654	1.21e-25	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
HHOLCGFJ_03655	7.2e-212	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
HHOLCGFJ_03656	1.37e-64	-	4.2.1.7	-	G	ko:K16849	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	SAF
HHOLCGFJ_03657	1.76e-277	-	4.2.1.7	-	G	ko:K16850	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	D-galactarate dehydratase / Altronate hydrolase, C terminus
HHOLCGFJ_03658	0.0	M1-1044	-	-	S	-	-	-	Belongs to the UPF0061 (SELO) family
HHOLCGFJ_03663	2.57e-36	-	-	-	-	-	-	-	-
HHOLCGFJ_03665	6.28e-128	-	-	-	-	-	-	-	-
HHOLCGFJ_03666	6.26e-214	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HHOLCGFJ_03667	0.0	-	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HHOLCGFJ_03668	5.07e-202	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HHOLCGFJ_03669	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
HHOLCGFJ_03670	2.11e-89	-	-	-	J	-	-	-	L-PSP family endoribonuclease
HHOLCGFJ_03671	3.42e-297	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
HHOLCGFJ_03672	2.77e-94	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HHOLCGFJ_03673	3.25e-97	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHOLCGFJ_03674	7.01e-131	azlC	-	-	E	-	-	-	AzlC protein
HHOLCGFJ_03675	1.98e-65	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
HHOLCGFJ_03676	2.54e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HHOLCGFJ_03678	5.22e-75	-	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HHOLCGFJ_03679	3.78e-97	-	-	-	K	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HHOLCGFJ_03680	0.0	-	-	-	L	-	-	-	ABC transporter
HHOLCGFJ_03681	1.23e-166	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
HHOLCGFJ_03682	5.32e-285	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HHOLCGFJ_03683	1.14e-255	-	-	-	K	-	-	-	ArsR family transcriptional regulator
HHOLCGFJ_03684	5.66e-85	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHOLCGFJ_03685	4.82e-254	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HHOLCGFJ_03686	3.68e-152	ydhC	-	-	K	-	-	-	FCD
HHOLCGFJ_03687	3.63e-214	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HHOLCGFJ_03689	4.15e-304	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HHOLCGFJ_03692	2.2e-291	ydfA	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHOLCGFJ_03693	2.84e-72	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HHOLCGFJ_03694	1.2e-101	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HHOLCGFJ_03695	7.28e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HHOLCGFJ_03696	6.04e-220	mviM3	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HHOLCGFJ_03697	6.34e-183	-	-	-	S	-	-	-	TraX protein
HHOLCGFJ_03698	2.53e-127	yrkC	-	-	G	-	-	-	Cupin domain
HHOLCGFJ_03699	1.62e-60	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
HHOLCGFJ_03700	2.11e-121	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HHOLCGFJ_03701	0.0	-	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HHOLCGFJ_03702	1.65e-23	-	-	-	K	-	-	-	transcriptional regulator
HHOLCGFJ_03703	6.06e-28	-	-	-	-	-	-	-	-
HHOLCGFJ_03704	7.35e-107	-	-	-	-	-	-	-	-
HHOLCGFJ_03705	6.5e-201	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HHOLCGFJ_03708	3.17e-167	-	-	-	M	-	-	-	Lysozyme-like
HHOLCGFJ_03709	6.52e-164	-	-	-	S	-	-	-	maturation of SSU-rRNA
HHOLCGFJ_03711	0.0	yddE	-	-	S	-	-	-	AAA-like domain
HHOLCGFJ_03712	6.71e-70	yddD	-	-	S	-	-	-	TcpE family
HHOLCGFJ_03713	2.61e-19	yddC	-	-	-	-	-	-	-
HHOLCGFJ_03714	1.92e-66	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
HHOLCGFJ_03718	3.58e-185	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
HHOLCGFJ_03719	2.81e-196	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
HHOLCGFJ_03720	6.78e-48	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
HHOLCGFJ_03721	1.69e-05	-	-	-	-	-	-	-	-
HHOLCGFJ_03722	6.71e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
HHOLCGFJ_03723	1.44e-15	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HHOLCGFJ_03724	1.46e-174	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
HHOLCGFJ_03732	1.4e-114	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HHOLCGFJ_03733	3.43e-13	-	-	-	-	-	-	-	-
HHOLCGFJ_03734	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HHOLCGFJ_03735	7.84e-152	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HHOLCGFJ_03736	1.49e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHOLCGFJ_03737	9.7e-109	rsbW	2.7.11.1	-	T	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HHOLCGFJ_03738	8.36e-72	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HHOLCGFJ_03739	1.25e-238	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HHOLCGFJ_03740	3.52e-96	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HHOLCGFJ_03741	2.69e-70	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HHOLCGFJ_03742	1.32e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HHOLCGFJ_03743	1.53e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HHOLCGFJ_03744	4.38e-35	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HHOLCGFJ_03745	1.68e-293	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHOLCGFJ_03746	3.58e-239	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HHOLCGFJ_03747	1.69e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHOLCGFJ_03748	2.89e-174	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HHOLCGFJ_03749	8.21e-132	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHOLCGFJ_03750	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HHOLCGFJ_03751	2.71e-182	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HHOLCGFJ_03752	5.02e-63	-	-	-	-	-	-	-	-
HHOLCGFJ_03753	4.49e-143	-	-	-	S	-	-	-	Integral membrane protein
HHOLCGFJ_03754	3.7e-281	-	-	-	S	ko:K09927	-	ko00000	Winged helix DNA-binding domain
HHOLCGFJ_03755	7.18e-181	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHOLCGFJ_03756	5.37e-248	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_03757	2.55e-248	-	-	-	G	-	-	-	Xylose isomerase
HHOLCGFJ_03758	3.61e-208	-	-	-	S	-	-	-	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
HHOLCGFJ_03759	7.98e-80	-	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HHOLCGFJ_03760	2.23e-51	mnhF2	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHOLCGFJ_03761	2.82e-111	mnhE2	-	-	P	ko:K05569	-	ko00000,ko02000	Na+/H+ ion antiporter subunit
HHOLCGFJ_03762	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHOLCGFJ_03763	1.85e-66	mnhC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHOLCGFJ_03764	6.87e-88	mnhB2	-	-	P	ko:K05566	-	ko00000,ko02000	antiporter activity
HHOLCGFJ_03765	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HHOLCGFJ_03766	6.16e-168	-	-	-	T	-	-	-	Universal stress protein family
HHOLCGFJ_03767	5.35e-145	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HHOLCGFJ_03768	4.14e-79	hxlR	-	-	K	-	-	-	transcriptional
HHOLCGFJ_03769	1.84e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_03770	5.84e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HHOLCGFJ_03771	3.15e-228	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HHOLCGFJ_03772	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLCGFJ_03773	3.3e-235	dppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_03774	1e-220	dppC	-	-	EP	ko:K16201	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_03775	6.94e-209	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_03776	5.06e-194	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HHOLCGFJ_03777	2.52e-301	-	2.7.13.3	-	T	ko:K07706,ko:K07717	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase-like ATPases
HHOLCGFJ_03778	2.15e-203	-	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HHOLCGFJ_03779	8.58e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHOLCGFJ_03780	4.65e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHOLCGFJ_03781	5.66e-191	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HHOLCGFJ_03782	3.02e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HHOLCGFJ_03783	2.05e-203	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HHOLCGFJ_03784	2.91e-258	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HHOLCGFJ_03785	3.15e-257	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HHOLCGFJ_03786	8.4e-297	yukF	-	-	QT	-	-	-	Transcriptional regulator
HHOLCGFJ_03787	5.77e-210	sseA	2.8.1.1, 2.8.1.2	-	P	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	ko00000,ko00001,ko01000	sulfurtransferase
HHOLCGFJ_03788	0.0	-	-	-	E	ko:K03294,ko:K14052	-	ko00000,ko02000	Amino acid permease
HHOLCGFJ_03789	1.56e-89	cwlK	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
HHOLCGFJ_03790	2.23e-298	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_03791	2.91e-256	aprE	3.4.21.62	-	O	ko:K01342	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HHOLCGFJ_03793	1.23e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHOLCGFJ_03794	9.32e-222	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
HHOLCGFJ_03795	6.79e-181	-	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HHOLCGFJ_03796	1.8e-226	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HHOLCGFJ_03797	1.35e-169	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HHOLCGFJ_03798	9.08e-124	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HHOLCGFJ_03799	4.31e-166	-	-	-	-	ko:K06336	-	ko00000,ko01002	-
HHOLCGFJ_03800	4.48e-123	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HHOLCGFJ_03801	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HHOLCGFJ_03802	2.25e-200	hisJ3	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
HHOLCGFJ_03803	5.96e-240	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HHOLCGFJ_03804	9.8e-147	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHOLCGFJ_03805	1.11e-166	-	-	-	-	-	-	-	-
HHOLCGFJ_03806	6.83e-252	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HHOLCGFJ_03807	2.22e-256	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Sugar diacid utilization regulator
HHOLCGFJ_03808	4.92e-266	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HHOLCGFJ_03809	4.21e-105	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHOLCGFJ_03810	1.98e-186	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HHOLCGFJ_03811	1.16e-107	yvbK	-	-	K	-	-	-	acetyltransferase
HHOLCGFJ_03812	1.18e-311	-	-	-	EK	-	-	-	Alanine-glyoxylate amino-transferase
HHOLCGFJ_03813	1.47e-116	-	3.1.1.29	-	K	ko:K01056	-	ko00000,ko01000,ko03012	-acetyltransferase
HHOLCGFJ_03814	2.33e-74	-	-	-	-	-	-	-	-
HHOLCGFJ_03815	2.16e-99	-	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HHOLCGFJ_03816	3.13e-282	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HHOLCGFJ_03817	2.08e-138	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHOLCGFJ_03818	1.93e-264	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_03819	7.66e-251	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HHOLCGFJ_03820	8.93e-219	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_03821	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HHOLCGFJ_03822	4.54e-144	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HHOLCGFJ_03823	7.3e-131	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HHOLCGFJ_03824	1.14e-52	-	-	-	-	-	-	-	-
HHOLCGFJ_03825	7.53e-206	ytcP1	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03826	9.97e-221	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03827	6.3e-292	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
HHOLCGFJ_03828	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_03829	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_03830	7.08e-166	-	-	-	S	-	-	-	YwiC-like protein
HHOLCGFJ_03831	0.0	narK	-	-	P	ko:K02575,ko:K10850	ko00910,ko02020,map00910,map02020	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HHOLCGFJ_03832	8.71e-148	nreC	-	-	T	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHOLCGFJ_03833	1.56e-254	nreB	2.7.13.3	-	T	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HHOLCGFJ_03834	1.45e-108	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	phosphoenolpyruvate-protein phosphotransferase activity
HHOLCGFJ_03835	9.42e-163	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	nitrate reductase, gamma subunit
HHOLCGFJ_03836	4.77e-151	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
HHOLCGFJ_03837	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HHOLCGFJ_03838	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHOLCGFJ_03839	3.29e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HHOLCGFJ_03840	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_03841	8.63e-154	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HHOLCGFJ_03842	3.12e-181	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HHOLCGFJ_03843	1.7e-106	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HHOLCGFJ_03844	5.98e-116	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HHOLCGFJ_03845	0.0	-	-	-	Q	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HHOLCGFJ_03846	1.01e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system, ATPase component
HHOLCGFJ_03852	3.24e-223	-	-	-	G	-	-	-	Glycoside hydrolase family 16
HHOLCGFJ_03856	6.99e-115	-	-	-	-	-	-	-	-
HHOLCGFJ_03858	0.0	-	-	-	S	-	-	-	nuclease activity
HHOLCGFJ_03859	3.83e-104	-	-	-	-	-	-	-	-
HHOLCGFJ_03860	4.05e-64	-	-	-	-	-	-	-	-
HHOLCGFJ_03861	4.22e-60	-	-	-	-	-	-	-	-
HHOLCGFJ_03862	2.51e-93	-	-	-	S	-	-	-	Family of unknown function (DUF5383)
HHOLCGFJ_03863	0.0	yueB	-	-	S	-	-	-	domain protein
HHOLCGFJ_03864	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HHOLCGFJ_03865	5.39e-278	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HHOLCGFJ_03866	7.61e-52	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HHOLCGFJ_03867	3.62e-65	esxA	-	-	S	-	-	-	Belongs to the WXG100 family
HHOLCGFJ_03868	3.86e-204	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03869	9.01e-198	M1-465	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_03870	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_03871	6.07e-223	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_03872	3.54e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HHOLCGFJ_03873	2.79e-195	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HHOLCGFJ_03874	4.65e-182	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HHOLCGFJ_03875	0.0	hscC	-	-	O	ko:K04045	-	ko00000,ko03110	Hsp70 protein
HHOLCGFJ_03876	0.0	-	-	-	O	-	-	-	DnaJ molecular chaperone homology domain
HHOLCGFJ_03878	9.63e-291	-	-	-	G	-	-	-	Metalloenzyme superfamily
HHOLCGFJ_03879	3.3e-281	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
HHOLCGFJ_03880	3.72e-262	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
HHOLCGFJ_03881	6.07e-223	php	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
HHOLCGFJ_03882	3.44e-283	-	-	-	S	-	-	-	Protein of unknown function
HHOLCGFJ_03883	1.98e-76	-	-	-	S	-	-	-	Protein of unknown function DUF2620
HHOLCGFJ_03884	9.89e-76	-	-	-	S	-	-	-	PRD domain
HHOLCGFJ_03885	1.99e-207	-	-	-	P	-	-	-	YhfZ C-terminal domain
HHOLCGFJ_03886	7.63e-249	-	-	-	G	-	-	-	Acyltransferase family
HHOLCGFJ_03887	7.48e-162	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HHOLCGFJ_03888	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HHOLCGFJ_03889	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HHOLCGFJ_03890	3.14e-167	-	-	-	T	-	-	-	Response regulator receiver domain
HHOLCGFJ_03891	1.61e-293	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HHOLCGFJ_03893	4.22e-293	lacE3	-	-	G	ko:K10240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
HHOLCGFJ_03894	8.82e-213	cebF	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHOLCGFJ_03895	6.65e-196	araQ5	-	-	P	ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HHOLCGFJ_03898	1.8e-187	ykuG	-	-	M	-	-	-	Putative peptidoglycan binding domain
HHOLCGFJ_03900	1.98e-285	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HHOLCGFJ_03901	2.52e-239	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
HHOLCGFJ_03902	8.5e-303	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
HHOLCGFJ_03903	5e-174	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HHOLCGFJ_03904	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HHOLCGFJ_03905	3.9e-286	gerAC1	-	-	S	ko:K06297	-	ko00000	spore germination
HHOLCGFJ_03907	6.76e-268	-	-	-	E	ko:K06296	-	ko00000,ko02000	Spore germination protein
HHOLCGFJ_03908	2.93e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HHOLCGFJ_03909	7.22e-205	kynA	1.13.11.11	-	E	ko:K00453	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko00002,ko01000	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
HHOLCGFJ_03910	1.4e-152	kynB	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HHOLCGFJ_03911	0.0	kynU	3.7.1.3	-	E	ko:K01556	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
HHOLCGFJ_03912	1.03e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HHOLCGFJ_03913	1.13e-290	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
HHOLCGFJ_03914	6.08e-73	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HHOLCGFJ_03915	1.2e-65	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HHOLCGFJ_03916	0.0	chiA	3.2.1.14	GH18	G	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycoside Hydrolase Family 18
HHOLCGFJ_03917	6.12e-179	ybgA	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HHOLCGFJ_03918	1.24e-179	celCD	2.7.1.196, 2.7.1.205, 3.5.1.105	-	G	ko:K02759,ko:K03478	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
HHOLCGFJ_03919	0.0	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHOLCGFJ_03920	2.9e-310	ywbA	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHOLCGFJ_03921	1.82e-71	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_03922	1.21e-59	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_03923	9.43e-172	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HHOLCGFJ_03924	1.88e-125	-	-	-	-	-	-	-	-
HHOLCGFJ_03925	5.3e-215	-	-	-	P	-	-	-	Arsenic resistance protein
HHOLCGFJ_03926	2.28e-242	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HHOLCGFJ_03927	2.38e-133	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_03928	1.86e-134	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HHOLCGFJ_03929	1.9e-125	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin ABC transporter permease
HHOLCGFJ_03930	9.09e-235	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_03931	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHOLCGFJ_03932	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHOLCGFJ_03933	2.79e-11	yqbO1	-	-	S	-	-	-	Domain of unknown function (DUF370)
HHOLCGFJ_03934	1.98e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHOLCGFJ_03935	9.82e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HHOLCGFJ_03936	4.21e-265	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHOLCGFJ_03937	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHOLCGFJ_03938	2.52e-22	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HHOLCGFJ_03939	8.89e-80	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHOLCGFJ_03940	7.48e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHOLCGFJ_03941	6.15e-146	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HHOLCGFJ_03942	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHOLCGFJ_03943	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHOLCGFJ_03944	7.14e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HHOLCGFJ_03945	2.58e-192	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HHOLCGFJ_03946	2.04e-174	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HHOLCGFJ_03947	7.4e-195	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HHOLCGFJ_03948	8.36e-278	-	-	-	E	-	-	-	Aminotransferase class-V
HHOLCGFJ_03949	5.94e-148	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HHOLCGFJ_03950	1.43e-230	yyaD	-	-	S	-	-	-	Membrane
HHOLCGFJ_03951	1.19e-37	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_03952	5.67e-246	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHOLCGFJ_03953	3.39e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HHOLCGFJ_03954	4.35e-92	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHOLCGFJ_03955	4.32e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHOLCGFJ_03956	9.14e-190	yybS	-	-	S	-	-	-	membrane
HHOLCGFJ_03957	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HHOLCGFJ_03958	3.46e-89	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HHOLCGFJ_03959	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HHOLCGFJ_03960	1.94e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHOLCGFJ_03966	2.06e-170	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_03967	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_03968	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_03969	2.27e-214	yycI	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_03970	3.29e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HHOLCGFJ_03971	6.27e-271	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHOLCGFJ_03972	6.79e-12	-	-	-	S	-	-	-	YyzF-like protein
HHOLCGFJ_03973	2.04e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHOLCGFJ_03974	3.97e-66	-	-	-	-	-	-	-	-
HHOLCGFJ_03975	6.33e-97	-	-	-	L	ko:K02057,ko:K03546	-	ko00000,ko00002,ko02000,ko03400	ATPase involved in DNA repair
HHOLCGFJ_03976	9.48e-22	-	-	-	S	-	-	-	Small GTP-binding protein
HHOLCGFJ_03977	2.55e-145	-	-	-	-	-	-	-	-
HHOLCGFJ_03978	4.75e-304	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
HHOLCGFJ_03979	1.71e-141	-	-	-	K	-	-	-	FCD domain
HHOLCGFJ_03980	9.87e-239	tdh	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HHOLCGFJ_03981	5.69e-235	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HHOLCGFJ_03982	1.83e-101	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HHOLCGFJ_03983	1.46e-269	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HHOLCGFJ_03984	7.79e-157	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
HHOLCGFJ_03986	5.87e-193	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HHOLCGFJ_03987	2.67e-144	-	-	-	S	-	-	-	ABC-2 family transporter protein
HHOLCGFJ_03989	3.61e-175	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HHOLCGFJ_03990	5.96e-12	-	-	-	-	-	-	-	-
HHOLCGFJ_03991	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HHOLCGFJ_03992	1.88e-223	appB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_03993	5.32e-214	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_03994	4.14e-231	oppD3	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_03995	5.07e-235	oppF3	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_03996	3.26e-265	-	-	-	S	-	-	-	domain protein
HHOLCGFJ_03997	0.0	ydfJ	-	-	S	ko:K07003	-	ko00000	MMPL family
HHOLCGFJ_03998	1.26e-136	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_03999	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_04000	2.58e-173	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HHOLCGFJ_04001	0.0	-	-	-	T	-	-	-	Carbon starvation protein
HHOLCGFJ_04002	2.42e-110	-	-	-	-	-	-	-	-
HHOLCGFJ_04004	9.91e-150	-	-	-	S	-	-	-	CGNR zinc finger
HHOLCGFJ_04005	4.83e-98	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HHOLCGFJ_04006	1.05e-232	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HHOLCGFJ_04007	2.92e-126	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HHOLCGFJ_04008	6.73e-183	-	1.14.14.35	-	C	ko:K17228	ko00920,map00920	ko00000,ko00001,ko01000	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHOLCGFJ_04009	1.41e-186	-	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HHOLCGFJ_04010	1.23e-235	-	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HHOLCGFJ_04011	1.97e-243	-	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HHOLCGFJ_04012	5.43e-138	sfbA	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
HHOLCGFJ_04013	1.49e-111	-	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HHOLCGFJ_04014	1.91e-110	metI1	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_04015	1.08e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3986)
HHOLCGFJ_04016	6.25e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_04017	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HHOLCGFJ_04018	9.28e-249	yjmC	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
HHOLCGFJ_04019	1.22e-148	kdgR	-	-	K	-	-	-	FCD
HHOLCGFJ_04020	6.91e-235	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HHOLCGFJ_04021	2.99e-98	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HHOLCGFJ_04022	8.5e-271	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HHOLCGFJ_04023	1.63e-258	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HHOLCGFJ_04024	4.53e-206	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_04025	3.43e-236	-	-	-	S	ko:K07080	-	ko00000	NMT1-like family
HHOLCGFJ_04026	0.0	-	-	-	S	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
HHOLCGFJ_04027	1.26e-155	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HHOLCGFJ_04028	1.66e-158	-	-	-	K	-	-	-	COG2186 Transcriptional regulators
HHOLCGFJ_04029	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HHOLCGFJ_04030	1.22e-280	-	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HHOLCGFJ_04031	4.41e-291	lhgO	1.1.5.3	-	S	ko:K00111,ko:K15736	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HHOLCGFJ_04032	0.0	-	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HHOLCGFJ_04034	3.06e-285	codB	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
HHOLCGFJ_04035	1.88e-311	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HHOLCGFJ_04037	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
HHOLCGFJ_04038	7.36e-309	malE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HHOLCGFJ_04039	0.0	-	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HHOLCGFJ_04040	2.79e-190	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HHOLCGFJ_04041	5.52e-241	malR	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_04042	7.98e-309	atoE	-	-	I	ko:K02106	ko02020,map02020	ko00000,ko00001	Short chain fatty acid transporter
HHOLCGFJ_04043	1.29e-169	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HHOLCGFJ_04044	1.51e-147	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HHOLCGFJ_04045	0.0	-	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182	ko00130,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the UbiD family
HHOLCGFJ_04046	3.33e-241	mhqA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HHOLCGFJ_04047	5.66e-168	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HHOLCGFJ_04048	3.5e-292	yciC	-	-	S	-	-	-	GTPases (G3E family)
HHOLCGFJ_04049	4.64e-53	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHOLCGFJ_04050	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHOLCGFJ_04051	8.33e-193	degV	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_04052	1.25e-140	-	-	-	S	-	-	-	DUF218 domain
HHOLCGFJ_04054	4.59e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_04055	4.79e-151	M1-1017	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HHOLCGFJ_04057	6.91e-45	-	-	-	-	-	-	-	-
HHOLCGFJ_04059	2.26e-249	-	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HHOLCGFJ_04060	2.38e-227	-	-	-	S	-	-	-	amine dehydrogenase activity
HHOLCGFJ_04061	1.44e-156	-	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_04062	0.0	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_04063	2.58e-93	-	-	-	S	-	-	-	YtkA-like
HHOLCGFJ_04064	7.69e-87	eaeH	-	-	M	ko:K13735	ko05100,map05100	ko00000,ko00001	LysM domain
HHOLCGFJ_04065	1.32e-61	phhB	3.5.4.33, 4.2.1.96	-	H	ko:K01724,ko:K11991	ko00790,map00790	ko00000,ko00001,ko01000,ko03016,ko04147	pterin-4-alpha-carbinolamine dehydratase
HHOLCGFJ_04066	2.86e-304	-	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHOLCGFJ_04067	1.2e-190	ubiE	-	-	Q	-	-	-	Methyltransferase type 11
HHOLCGFJ_04068	7.98e-137	-	-	-	S	ko:K09962	-	ko00000	protein conserved in bacteria
HHOLCGFJ_04069	8.5e-285	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HHOLCGFJ_04070	2.77e-103	sdpI	-	-	S	-	-	-	integral membrane protein
HHOLCGFJ_04071	4.21e-302	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HHOLCGFJ_04072	9.85e-81	-	-	-	S	-	-	-	CHY zinc finger
HHOLCGFJ_04073	1.82e-226	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HHOLCGFJ_04074	1.4e-151	M1-740	-	-	I	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HHOLCGFJ_04075	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HHOLCGFJ_04076	9.65e-157	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HHOLCGFJ_04077	0.0	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	Sodium:sulfate symporter transmembrane region
HHOLCGFJ_04078	1.06e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HHOLCGFJ_04079	0.0	-	-	-	-	-	-	-	-
HHOLCGFJ_04081	0.0	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_04083	6.11e-256	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHOLCGFJ_04084	3.3e-180	-	-	-	S	-	-	-	GNAT acetyltransferase
HHOLCGFJ_04085	2.75e-91	-	-	-	-	-	-	-	-
HHOLCGFJ_04086	1.19e-89	-	-	-	-	-	-	-	-
HHOLCGFJ_04087	0.0	-	-	-	-	-	-	-	-
HHOLCGFJ_04088	1.6e-159	-	-	-	-	-	-	-	-
HHOLCGFJ_04089	1.81e-161	-	-	-	-	-	-	-	-
HHOLCGFJ_04090	4.69e-161	-	-	-	-	-	-	-	-
HHOLCGFJ_04091	1.65e-97	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
HHOLCGFJ_04092	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHOLCGFJ_04093	7.11e-116	-	-	-	K	-	-	-	GrpB protein
HHOLCGFJ_04094	8.63e-224	-	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HHOLCGFJ_04095	2.31e-182	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
HHOLCGFJ_04097	4.07e-215	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHOLCGFJ_04098	2.7e-147	yrbG	-	-	S	-	-	-	membrane
HHOLCGFJ_04099	1.11e-141	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHOLCGFJ_04100	1.09e-221	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HHOLCGFJ_04101	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HHOLCGFJ_04102	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HHOLCGFJ_04103	1.09e-127	-	-	-	S	-	-	-	DinB superfamily
HHOLCGFJ_04104	5e-274	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
HHOLCGFJ_04105	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHOLCGFJ_04106	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HHOLCGFJ_04107	6.2e-286	-	-	-	S	-	-	-	Acetyltransferase
HHOLCGFJ_04108	0.0	dapE	-	-	E	-	-	-	Peptidase dimerisation domain
HHOLCGFJ_04109	8.38e-189	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HHOLCGFJ_04110	4.61e-224	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HHOLCGFJ_04111	4.85e-181	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HHOLCGFJ_04112	3.98e-205	XK27_03890	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HHOLCGFJ_04113	1.37e-192	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HHOLCGFJ_04114	2.48e-129	-	-	-	S	-	-	-	UPF0302 domain
HHOLCGFJ_04115	7.27e-73	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HHOLCGFJ_04116	2.81e-57	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HHOLCGFJ_04117	3.64e-292	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HHOLCGFJ_04118	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHOLCGFJ_04119	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HHOLCGFJ_04120	2.44e-155	ydbC	-	-	G	-	-	-	Domain of unknown function (DUF4937
HHOLCGFJ_04121	1.56e-175	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HHOLCGFJ_04122	2.44e-243	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HHOLCGFJ_04123	5.89e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HHOLCGFJ_04125	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HHOLCGFJ_04126	1.25e-93	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HHOLCGFJ_04127	4.32e-105	bdbA	-	-	CO	-	-	-	Thioredoxin
HHOLCGFJ_04128	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHOLCGFJ_04129	1.28e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_04130	4.45e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HHOLCGFJ_04131	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
HHOLCGFJ_04132	2.64e-244	-	-	-	I	-	-	-	Fatty acid desaturase
HHOLCGFJ_04133	2.5e-300	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	methionine gamma-lyase
HHOLCGFJ_04134	5.03e-166	XK27_07210	-	-	S	-	-	-	B3/4 domain
HHOLCGFJ_04135	0.0	gntR9	-	-	K	-	-	-	Alanine-glyoxylate amino-transferase
HHOLCGFJ_04136	4.95e-161	-	-	-	E	-	-	-	AzlC protein
HHOLCGFJ_04137	5.89e-63	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HHOLCGFJ_04138	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HHOLCGFJ_04139	1.29e-190	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HHOLCGFJ_04140	1.44e-303	-	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_04141	1.7e-176	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHOLCGFJ_04142	1.79e-226	-	-	-	S	ko:K07120	-	ko00000	Pfam:AmoA
HHOLCGFJ_04143	1.68e-295	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HHOLCGFJ_04144	2.75e-217	-	-	-	T	ko:K07182	-	ko00000	Putative nucleotidyltransferase substrate binding domain
HHOLCGFJ_04145	9.46e-175	polC1	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
HHOLCGFJ_04146	1.26e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5327)
HHOLCGFJ_04147	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHOLCGFJ_04148	1.03e-145	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHOLCGFJ_04149	4.91e-78	ywdK	-	-	S	-	-	-	small membrane protein
HHOLCGFJ_04150	8.65e-107	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HHOLCGFJ_04151	1.38e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HHOLCGFJ_04152	4.24e-156	-	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HHOLCGFJ_04153	1.01e-169	-	-	-	-	-	-	-	-
HHOLCGFJ_04154	2.28e-84	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HHOLCGFJ_04155	8.47e-207	natA1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HHOLCGFJ_04156	5.34e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_04157	4.29e-252	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HHOLCGFJ_04158	3.16e-64	-	-	-	-	-	-	-	-
HHOLCGFJ_04159	2.12e-182	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHOLCGFJ_04160	1.35e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HHOLCGFJ_04161	1.1e-182	-	5.3.3.18	-	I	ko:K15866	ko00360,ko01120,map00360,map01120	ko00000,ko00001,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HHOLCGFJ_04162	3.69e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HHOLCGFJ_04163	1.91e-194	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HHOLCGFJ_04164	4.6e-273	gltP	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHOLCGFJ_04165	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HHOLCGFJ_04166	8.17e-119	ywgA	-	-	-	ko:K09388	-	ko00000	-
HHOLCGFJ_04168	2.41e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HHOLCGFJ_04169	5.89e-161	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HHOLCGFJ_04170	1.39e-257	-	-	-	F	-	-	-	S-adenosylhomocysteine deaminase activity
HHOLCGFJ_04171	1.67e-128	ywhD	-	-	S	-	-	-	YwhD family
HHOLCGFJ_04172	0.0	-	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HHOLCGFJ_04173	2.32e-199	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_04174	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HHOLCGFJ_04175	8.83e-205	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HHOLCGFJ_04176	2.02e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HHOLCGFJ_04177	1.89e-100	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_04178	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HHOLCGFJ_04179	6.53e-97	-	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HHOLCGFJ_04180	1.87e-76	ygzB	-	-	S	-	-	-	UPF0295 protein
HHOLCGFJ_04181	1.18e-103	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HHOLCGFJ_04182	6.47e-64	-	-	-	S	-	-	-	Cyclic-di-AMP receptor
HHOLCGFJ_04183	7.75e-231	ghrA	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOLCGFJ_04184	4.85e-116	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HHOLCGFJ_04185	5.04e-314	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HHOLCGFJ_04186	1.89e-237	ygaE	-	-	S	-	-	-	Membrane
HHOLCGFJ_04187	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HHOLCGFJ_04188	2.94e-133	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HHOLCGFJ_04189	6.03e-23	-	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HHOLCGFJ_04190	2.66e-168	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_04191	5.62e-27	yfhS	-	-	-	-	-	-	-
HHOLCGFJ_04192	3.86e-78	-	-	-	-	-	-	-	-
HHOLCGFJ_04193	2.28e-169	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOLCGFJ_04194	5.56e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HHOLCGFJ_04195	1.25e-241	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HHOLCGFJ_04197	9.25e-30	-	-	-	S	-	-	-	YpzG-like protein
HHOLCGFJ_04198	9.17e-70	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HHOLCGFJ_04199	5.82e-184	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HHOLCGFJ_04200	1.43e-218	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HHOLCGFJ_04201	4.73e-66	-	-	-	-	-	-	-	-
HHOLCGFJ_04202	1.62e-258	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HHOLCGFJ_04203	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHOLCGFJ_04204	1.88e-80	-	-	-	-	-	-	-	-
HHOLCGFJ_04205	1.23e-170	-	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHOLCGFJ_04206	2.51e-140	-	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_04207	2.34e-61	-	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_04208	7.62e-175	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_04209	4.2e-146	surE	3.1.3.5	-	S	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Survival protein SurE
HHOLCGFJ_04210	4.6e-107	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HHOLCGFJ_04211	2.06e-93	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_04212	1.16e-207	-	-	-	O	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HHOLCGFJ_04214	2.14e-188	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HHOLCGFJ_04215	1.86e-180	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HHOLCGFJ_04216	1.01e-310	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HHOLCGFJ_04217	8.1e-153	-	-	-	G	ko:K15640	-	ko00000	Belongs to the phosphoglycerate mutase family
HHOLCGFJ_04218	1.68e-279	yfkA	-	-	S	-	-	-	YfkB-like domain
HHOLCGFJ_04219	4.85e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
HHOLCGFJ_04222	1.21e-29	-	-	-	S	-	-	-	Fur-regulated basic protein B
HHOLCGFJ_04223	2.4e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HHOLCGFJ_04224	5.11e-242	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HHOLCGFJ_04225	4.13e-185	-	-	-	-	-	-	-	-
HHOLCGFJ_04226	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HHOLCGFJ_04227	0.0	kat	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HHOLCGFJ_04229	4.43e-58	-	-	-	L	-	-	-	Transposase IS200 like
HHOLCGFJ_04230	0.0	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
HHOLCGFJ_04231	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HHOLCGFJ_04232	4.23e-147	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Caulimovirus viroplasmin
HHOLCGFJ_04233	1.81e-54	-	-	-	-	-	-	-	-
HHOLCGFJ_04234	2.17e-62	-	-	-	K	-	-	-	SpoVT / AbrB like domain
HHOLCGFJ_04235	4.19e-75	-	-	-	-	-	-	-	-
HHOLCGFJ_04236	3.95e-308	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHOLCGFJ_04237	3.04e-233	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HHOLCGFJ_04238	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HHOLCGFJ_04239	1.35e-210	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HHOLCGFJ_04240	2.57e-173	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HHOLCGFJ_04241	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHOLCGFJ_04242	3.48e-269	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HHOLCGFJ_04243	1.13e-112	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HHOLCGFJ_04244	5.63e-164	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HHOLCGFJ_04245	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HHOLCGFJ_04246	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HHOLCGFJ_04247	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HHOLCGFJ_04248	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HHOLCGFJ_04249	2.84e-300	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHOLCGFJ_04250	1.91e-314	alsT	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HHOLCGFJ_04251	2.04e-122	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HHOLCGFJ_04252	0.0	glpD	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HHOLCGFJ_04253	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHOLCGFJ_04254	2.52e-298	kinB3	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_04255	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HHOLCGFJ_04256	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HHOLCGFJ_04257	0.0	uvrD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HHOLCGFJ_04258	5.37e-220	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HHOLCGFJ_04259	4.14e-173	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HHOLCGFJ_04260	1.22e-175	phnE	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHOLCGFJ_04261	3.66e-184	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HHOLCGFJ_04262	5.02e-186	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHOLCGFJ_04263	3.55e-313	-	-	-	V	-	-	-	MatE
HHOLCGFJ_04264	2.01e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HHOLCGFJ_04265	1.12e-209	pepI	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha/beta hydrolase family
HHOLCGFJ_04266	4.88e-207	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_04267	3.99e-233	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOLCGFJ_04268	0.0	hbpA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HHOLCGFJ_04269	6.99e-242	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_04270	5.69e-235	dppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HHOLCGFJ_04271	0.0	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HHOLCGFJ_04272	2.46e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HHOLCGFJ_04273	1.11e-133	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_04274	4.47e-294	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
HHOLCGFJ_04275	8.97e-227	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	transport system, periplasmic component
HHOLCGFJ_04276	1.2e-219	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HHOLCGFJ_04277	1.74e-181	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	transport system, ATPase component
HHOLCGFJ_04278	2.69e-248	-	-	-	-	-	-	-	-
HHOLCGFJ_04279	2.8e-256	cysA	3.6.3.25	-	P	ko:K02045	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HHOLCGFJ_04280	2.72e-172	cysW	-	-	P	ko:K02047	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG4208 ABC-type sulfate transport system, permease component
HHOLCGFJ_04281	7.52e-176	cysT	-	-	O	ko:K02046	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0555 ABC-type sulfate transport system, permease component
HHOLCGFJ_04282	1.61e-251	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG1613 ABC-type sulfate transport system, periplasmic component
HHOLCGFJ_04283	1.62e-106	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHOLCGFJ_04284	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HHOLCGFJ_04285	0.0	dld	1.1.2.4, 1.1.3.15	-	C	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HHOLCGFJ_04286	1.05e-206	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HHOLCGFJ_04287	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HHOLCGFJ_04288	3.19e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HHOLCGFJ_04289	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HHOLCGFJ_04290	1.92e-265	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HHOLCGFJ_04291	7.86e-87	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HHOLCGFJ_04292	2.5e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HHOLCGFJ_04293	2.34e-194	malG	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_04294	2.72e-222	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_04295	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_04296	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
HHOLCGFJ_04297	2.21e-221	yisR1	3.2.1.23	-	K	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	AraC-like ligand binding domain
HHOLCGFJ_04298	1.62e-161	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_04299	3.24e-170	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HHOLCGFJ_04300	1.05e-176	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HHOLCGFJ_04301	4.88e-161	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HHOLCGFJ_04302	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HHOLCGFJ_04303	3.42e-97	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHOLCGFJ_04304	1.05e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
HHOLCGFJ_04305	6.8e-135	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HHOLCGFJ_04306	0.0	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHOLCGFJ_04307	8.82e-124	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
HHOLCGFJ_04308	7.45e-101	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HHOLCGFJ_04309	8.85e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1569)
HHOLCGFJ_04310	1.87e-74	-	-	-	-	-	-	-	-
HHOLCGFJ_04311	1.92e-26	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	Belongs to the WXG100 family
HHOLCGFJ_04312	5.06e-103	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HHOLCGFJ_04313	3.42e-77	-	-	-	-	-	-	-	-
HHOLCGFJ_04314	7.56e-82	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HHOLCGFJ_04315	1.58e-89	-	-	-	-	-	-	-	-
HHOLCGFJ_04316	1.06e-305	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HHOLCGFJ_04317	2.83e-53	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
HHOLCGFJ_04318	7.76e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
HHOLCGFJ_04319	9.83e-191	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
HHOLCGFJ_04320	6.62e-140	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HHOLCGFJ_04321	3.84e-313	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HHOLCGFJ_04322	1.64e-151	yhcQ	-	-	M	-	-	-	Spore coat protein
HHOLCGFJ_04323	3.42e-06	-	-	-	S	-	-	-	Sporulation inhibitor A
HHOLCGFJ_04324	2e-213	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HHOLCGFJ_04325	6.74e-219	eutB	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HHOLCGFJ_04326	5.29e-268	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HHOLCGFJ_04327	1.02e-146	-	-	-	S	-	-	-	HTH domain
HHOLCGFJ_04328	8.12e-240	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Arginase family
HHOLCGFJ_04329	1.06e-166	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
HHOLCGFJ_04330	2.33e-259	-	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_04331	1.85e-211	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HHOLCGFJ_04332	2.59e-160	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HHOLCGFJ_04333	5.53e-151	ydfE	-	-	S	-	-	-	Flavin reductase like domain
HHOLCGFJ_04334	1.58e-148	-	-	-	S	-	-	-	ABC-2 family transporter protein
HHOLCGFJ_04335	1.12e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HHOLCGFJ_04336	2.23e-212	ycbM	-	-	T	-	-	-	Histidine kinase
HHOLCGFJ_04337	6.59e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHOLCGFJ_04338	6.95e-300	hisD	1.1.1.23, 1.1.1.308	-	E	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHOLCGFJ_04339	9.14e-218	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HHOLCGFJ_04340	1.67e-258	-	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HHOLCGFJ_04341	0.0	-	-	-	M	-	-	-	Domain of unknown function DUF11
HHOLCGFJ_04342	5.39e-130	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HHOLCGFJ_04343	8.68e-44	-	-	-	S	-	-	-	Sporulation inhibitor A
HHOLCGFJ_04344	5.75e-203	-	-	AA10,CBM73	D	ko:K03933	-	ko00000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HHOLCGFJ_04345	2.05e-182	-	1.1.1.140	-	C	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HHOLCGFJ_04346	5.88e-74	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HHOLCGFJ_04347	4.5e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol sorbitol-specific transporter subunit IIB
HHOLCGFJ_04348	2.27e-128	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HHOLCGFJ_04349	6.99e-99	srlR	-	-	K	-	-	-	Glucitol operon activator
HHOLCGFJ_04350	6.62e-222	-	-	-	K	-	-	-	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HHOLCGFJ_04351	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HHOLCGFJ_04352	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HHOLCGFJ_04353	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HHOLCGFJ_04354	1.27e-159	yteU	-	-	S	-	-	-	Integral membrane protein
HHOLCGFJ_04355	5.75e-103	-	-	-	G	-	-	-	carbohydrate transport
HHOLCGFJ_04356	1.28e-279	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HHOLCGFJ_04357	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HHOLCGFJ_04358	2.89e-223	-	-	-	E	-	-	-	Abhydrolase family
HHOLCGFJ_04359	5.67e-200	ytcP3	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_04360	1.19e-231	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HHOLCGFJ_04361	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HHOLCGFJ_04362	0.0	-	-	-	K	-	-	-	Transcriptional regulator
HHOLCGFJ_04363	5.96e-207	-	-	-	K	-	-	-	AraC-like ligand binding domain
HHOLCGFJ_04364	3.82e-254	-	4.2.2.2	-	M	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectic acid lyase
HHOLCGFJ_04365	5.72e-141	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HHOLCGFJ_04366	1.5e-169	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
HHOLCGFJ_04367	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HHOLCGFJ_04368	0.0	lplA3	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HHOLCGFJ_04369	2.76e-218	lplC1	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_04370	3.82e-229	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HHOLCGFJ_04371	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HHOLCGFJ_04372	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HHOLCGFJ_04373	0.0	yicI	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HHOLCGFJ_04374	2.13e-259	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HHOLCGFJ_04375	2.54e-243	nagC_1	-	-	GK	-	-	-	ROK family