ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HHEMLNNI_00001 3.57e-202 kbaY 4.1.2.13, 4.1.2.40 - G ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
HHEMLNNI_00002 6.2e-98 fruD 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHEMLNNI_00003 0.0 fruC 2.7.1.202 - G ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HHEMLNNI_00004 6.26e-218 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HHEMLNNI_00005 9.32e-182 rpl - - K - - - Helix-turn-helix domain, rpiR family
HHEMLNNI_00006 1.08e-211 XK27_03180 - - T - - - Belongs to the universal stress protein A family
HHEMLNNI_00007 4.3e-68 - - - - - - - -
HHEMLNNI_00008 4.26e-74 - - - - - - - -
HHEMLNNI_00009 8.98e-253 - - - E ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0687 Spermidine putrescine-binding periplasmic protein
HHEMLNNI_00010 2.38e-222 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HHEMLNNI_00011 7.59e-180 - - - E ko:K02054,ko:K11071 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1176 ABC-type spermidine putrescine transport system, permease component I
HHEMLNNI_00012 4.21e-172 potC3 - - P ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00013 2.56e-249 potA11 3.6.3.30 - P ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHEMLNNI_00014 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
HHEMLNNI_00015 0.0 M1-554 - - G - - - Endonuclease Exonuclease Phosphatase
HHEMLNNI_00016 5.51e-19 - - - S - - - Inner spore coat protein D
HHEMLNNI_00017 2.08e-81 - - - FJ - - - tRNA wobble adenosine to inosine editing
HHEMLNNI_00018 1.57e-201 - - - P ko:K02026,ko:K10190,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
HHEMLNNI_00019 2.52e-206 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00020 2.46e-310 - - - G - - - ABC transporter substrate-binding protein
HHEMLNNI_00021 1.41e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHEMLNNI_00022 0.0 ltaS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HHEMLNNI_00023 4.63e-175 lacR - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
HHEMLNNI_00024 6.98e-286 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHEMLNNI_00025 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HHEMLNNI_00026 9.24e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HHEMLNNI_00027 0.0 mdr - - EGP - - - the major facilitator superfamily
HHEMLNNI_00028 0.0 rocB - - E - - - arginine degradation protein
HHEMLNNI_00029 8.9e-216 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HHEMLNNI_00030 6.2e-65 - - - - - - - -
HHEMLNNI_00031 3.63e-172 yvcP - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_00032 2.27e-247 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HHEMLNNI_00033 6.61e-183 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_00034 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HHEMLNNI_00036 0.0 - 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HHEMLNNI_00037 2.33e-206 - - - S - - - CAAX amino terminal protease family protein
HHEMLNNI_00038 2.66e-220 - - - K - - - Putative sugar-binding domain
HHEMLNNI_00039 5.44e-79 - 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HHEMLNNI_00040 3.7e-235 - 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol sorbitol-specific transporter subunit IIB
HHEMLNNI_00041 8.78e-115 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HHEMLNNI_00042 1.9e-89 - - - K - - - Glucitol operon activator protein (GutM)
HHEMLNNI_00043 6.17e-300 - - - E - - - SAF
HHEMLNNI_00044 4.83e-50 - - - G - - - PTS HPr component phosphorylation site
HHEMLNNI_00045 1.13e-157 - - - - - - - -
HHEMLNNI_00046 4.23e-123 - - - S - - - VanZ like family
HHEMLNNI_00047 2.44e-104 yybA - - K - - - transcriptional
HHEMLNNI_00048 2.83e-121 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHEMLNNI_00049 1.48e-222 ssuA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HHEMLNNI_00050 2.49e-134 ssuC_2 - - P ko:K02050,ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00051 1.99e-199 ssuB - - P ko:K02049 - ko00000,ko00002,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HHEMLNNI_00052 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HHEMLNNI_00053 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HHEMLNNI_00054 1.21e-264 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HHEMLNNI_00055 1.69e-296 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HHEMLNNI_00056 2.65e-181 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHEMLNNI_00057 1.83e-231 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HHEMLNNI_00059 0.0 - 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HHEMLNNI_00060 6.74e-112 - - - - - - - -
HHEMLNNI_00061 2.58e-163 - - - S - - - KR domain
HHEMLNNI_00062 2.18e-75 - - - S - - - Family of unknown function (DUF5367)
HHEMLNNI_00063 1.72e-135 - - - K - - - Bacterial regulatory proteins, tetR family
HHEMLNNI_00065 2.73e-209 - - - EG - - - EamA-like transporter family
HHEMLNNI_00066 0.0 ywoF - - P - - - Right handed beta helix region
HHEMLNNI_00067 3.16e-114 mutT 3.6.1.13, 3.6.1.55 - L ko:K01515,ko:K03574 ko00230,map00230 ko00000,ko00001,ko01000,ko03400 nUDIX hydrolase
HHEMLNNI_00068 2.25e-78 - - - S - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHEMLNNI_00069 2.07e-122 - - - S - - - RES domain
HHEMLNNI_00070 1.04e-107 - - - - - - - -
HHEMLNNI_00071 3.29e-100 - - - - - - - -
HHEMLNNI_00072 0.0 - - - G - - - Bacterial extracellular solute-binding protein
HHEMLNNI_00073 1.82e-191 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00074 1.78e-209 - - - G - - - Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00075 3.12e-277 - 3.2.1.180 GH88 O ko:K18581 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HHEMLNNI_00076 2.47e-220 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_00077 3.9e-289 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_00078 1.72e-269 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_00079 1.08e-132 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_00080 2.32e-184 inoDHR - - G - - - Xylose isomerase-like TIM barrel
HHEMLNNI_00081 4.18e-200 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00082 2.28e-219 ugpA7 - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00083 0.0 - - - G - - - Bacterial extracellular solute-binding protein
HHEMLNNI_00084 2.45e-268 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_00085 5.46e-181 - - - G - - - Xylose isomerase-like TIM barrel
HHEMLNNI_00086 8.28e-222 - - - K - - - Cupin domain
HHEMLNNI_00087 2.26e-244 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HHEMLNNI_00088 2.16e-86 - - - S - - - Protein of unknown function, DUF393
HHEMLNNI_00089 1.64e-206 yfhB - - S - - - PhzF family
HHEMLNNI_00090 2.46e-133 - - - V - - - Beta-lactamase
HHEMLNNI_00091 1.01e-118 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHEMLNNI_00092 0.0 - - - E - - - Aminotransferase class-V
HHEMLNNI_00093 0.0 - - - M - - - Sulfatase
HHEMLNNI_00094 2.79e-90 - - - E ko:K07032 - ko00000 lactoylglutathione lyase activity
HHEMLNNI_00095 2.83e-201 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HHEMLNNI_00097 1.26e-215 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HHEMLNNI_00098 9.75e-202 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HHEMLNNI_00099 1.45e-45 yisX - - S - - - Pentapeptide repeats (9 copies)
HHEMLNNI_00100 3.03e-190 araQ - - P ko:K10190,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
HHEMLNNI_00101 2.95e-206 - - - G ko:K10189 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00102 2.57e-310 - - - G ko:K10188 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHEMLNNI_00103 2.24e-66 - - - S - - - Branched-chain amino acid transport protein (AzlD)
HHEMLNNI_00104 3.11e-153 - - - E - - - AzlC protein
HHEMLNNI_00105 1.84e-126 - - - K - - - Helix-turn-helix XRE-family like proteins
HHEMLNNI_00106 1.21e-120 M1-753 - - M - - - FR47-like protein
HHEMLNNI_00107 1.19e-184 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase domain
HHEMLNNI_00109 5.27e-49 ydaS - - S - - - membrane
HHEMLNNI_00110 1.01e-123 ywmF - - S - - - Peptidase M50
HHEMLNNI_00111 4.36e-194 - 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HHEMLNNI_00112 1.78e-86 - 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HHEMLNNI_00113 2.15e-153 ypgQ - - S ko:K06950 - ko00000 phosphohydrolase
HHEMLNNI_00114 4.22e-37 - - - - - - - -
HHEMLNNI_00115 0.0 apc3 - - EQ - - - Hydantoinase/oxoprolinase
HHEMLNNI_00116 1.07e-263 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
HHEMLNNI_00117 6.62e-280 - - - F ko:K10974 - ko00000,ko02000 cytosine purines uracil thiamine allantoin
HHEMLNNI_00118 1.84e-136 - - - K - - - Bacterial regulatory proteins, tetR family
HHEMLNNI_00119 3.79e-182 - - - K - - - acetyltransferase
HHEMLNNI_00120 1.25e-108 - - - S ko:K06385 - ko00000 Stage II sporulation protein P (SpoIIP)
HHEMLNNI_00121 8.2e-211 - 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein kinase domain
HHEMLNNI_00122 1.68e-76 - - - FG ko:K02503 - ko00000,ko04147 HIT domain
HHEMLNNI_00123 1.7e-234 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HHEMLNNI_00124 3.23e-133 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
HHEMLNNI_00125 2.15e-121 - - - - - - - -
HHEMLNNI_00127 6.13e-233 - - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HHEMLNNI_00128 5.73e-301 - - - S - - - protein conserved in bacteria
HHEMLNNI_00129 0.0 - 3.5.4.28, 3.5.4.31 - F ko:K12960 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HHEMLNNI_00130 8.73e-287 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHEMLNNI_00131 0.0 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
HHEMLNNI_00132 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HHEMLNNI_00133 0.0 - - - T - - - COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HHEMLNNI_00134 1.15e-280 - - - G - - - Transmembrane secretion effector
HHEMLNNI_00135 1.27e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_00136 9.11e-134 desR - - K ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HHEMLNNI_00137 2.32e-153 - - - - - - - -
HHEMLNNI_00138 5.5e-200 - - - K ko:K03488 - ko00000,ko03000 antiterminator
HHEMLNNI_00139 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HHEMLNNI_00140 7.39e-224 - 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HHEMLNNI_00141 9.66e-129 ydhK - - M - - - Protein of unknown function (DUF1541)
HHEMLNNI_00142 1.83e-92 - - - - - - - -
HHEMLNNI_00143 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HHEMLNNI_00144 3.24e-257 gatD 1.1.1.14, 1.1.1.251 - C ko:K00008,ko:K00094 ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100 ko00000,ko00001,ko00002,ko01000 Alcohol dehydrogenase GroES-like domain
HHEMLNNI_00145 1.15e-29 - - - - - - - -
HHEMLNNI_00146 4.25e-248 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHEMLNNI_00147 6.01e-287 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3775 Phosphotransferase system, galactitol-specific IIC component
HHEMLNNI_00148 3.67e-57 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HHEMLNNI_00149 2.73e-104 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHEMLNNI_00150 0.0 - - - GKT - - - COG3711 Transcriptional antiterminator
HHEMLNNI_00151 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HHEMLNNI_00153 1.55e-252 - - - - - - - -
HHEMLNNI_00154 7.47e-141 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HHEMLNNI_00155 1.01e-226 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HHEMLNNI_00156 2.52e-142 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHEMLNNI_00157 4.44e-123 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HHEMLNNI_00158 1.38e-264 siaT_3 - - G - - - COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HHEMLNNI_00159 9.62e-111 - - - G - - - Tripartite ATP-independent periplasmic transporters, DctQ component
HHEMLNNI_00160 3.99e-233 - - - G - - - Bacterial extracellular solute-binding protein, family 7
HHEMLNNI_00161 9.8e-234 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
HHEMLNNI_00162 4.89e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HHEMLNNI_00163 8.01e-97 - - - - - - - -
HHEMLNNI_00164 3.13e-101 - - - - - - - -
HHEMLNNI_00165 8.02e-255 ysdC_3 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 M42 glutamyl aminopeptidase
HHEMLNNI_00166 7.46e-59 M1-485 - - S - - - Membrane
HHEMLNNI_00167 2.07e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HHEMLNNI_00168 3.05e-225 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HHEMLNNI_00169 7.93e-179 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HHEMLNNI_00170 1.48e-143 - - - S ko:K06976 - ko00000 GNAT acetyltransferase
HHEMLNNI_00171 0.0 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HHEMLNNI_00172 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HHEMLNNI_00173 5.64e-35 - - - - - - - -
HHEMLNNI_00174 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HHEMLNNI_00175 2.3e-178 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HHEMLNNI_00176 3.63e-143 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HHEMLNNI_00177 3.83e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHEMLNNI_00178 4.22e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_00179 7.66e-163 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HHEMLNNI_00180 1.67e-135 - - - - - - - -
HHEMLNNI_00181 2.51e-06 liaI - - - ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 -
HHEMLNNI_00182 6.65e-51 - - - - - - - -
HHEMLNNI_00183 4.08e-149 - - - S - - - Cupin
HHEMLNNI_00184 0.0 - - - M - - - glycoside hydrolase family 81
HHEMLNNI_00185 7.61e-247 cytR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HHEMLNNI_00186 3.83e-165 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HHEMLNNI_00187 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHEMLNNI_00188 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHEMLNNI_00189 2.28e-221 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_00190 2.58e-227 - - - K - - - WYL domain
HHEMLNNI_00191 3.74e-149 - 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HHEMLNNI_00192 1.5e-197 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHEMLNNI_00193 1.23e-202 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
HHEMLNNI_00194 1.69e-65 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HHEMLNNI_00195 5.77e-214 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_00196 0.0 gdhA 1.4.1.2, 1.4.1.4 - E ko:K00260,ko:K00262 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HHEMLNNI_00197 6.85e-179 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHEMLNNI_00198 4.27e-225 - - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHEMLNNI_00199 2.3e-259 - 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HHEMLNNI_00200 1.33e-176 ssuB - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HHEMLNNI_00201 6.41e-77 - - - S - - - Dinitrogenase iron-molybdenum cofactor
HHEMLNNI_00202 2.87e-316 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHEMLNNI_00203 4.99e-119 ssuE 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
HHEMLNNI_00204 1.3e-209 ytlI3 - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
HHEMLNNI_00205 6.99e-112 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HHEMLNNI_00206 1.6e-148 - - - S - - - membrane
HHEMLNNI_00207 1.03e-37 - - - S - - - spore protein
HHEMLNNI_00208 4.37e-39 - - - S ko:K06418,ko:K06419 - ko00000 spore protein
HHEMLNNI_00209 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHEMLNNI_00211 7.78e-202 yerO - - K - - - Transcriptional regulator
HHEMLNNI_00212 1.38e-165 - - - - - - - -
HHEMLNNI_00213 3.75e-210 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HHEMLNNI_00214 8.89e-80 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HHEMLNNI_00215 6.44e-145 - - - Q - - - Methyltransferase domain
HHEMLNNI_00216 8.33e-186 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HHEMLNNI_00217 2.54e-10 - - - - - - - -
HHEMLNNI_00218 1.46e-285 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHEMLNNI_00219 1.73e-216 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HHEMLNNI_00220 9.97e-41 - - - - - - - -
HHEMLNNI_00222 1.35e-89 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_00225 8.3e-223 - - - P ko:K07217 - ko00000 Catalase
HHEMLNNI_00226 0.0 - - - S - - - Predicted membrane protein (DUF2254)
HHEMLNNI_00227 4.92e-207 - - - E ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Glycine betaine ABC transporter
HHEMLNNI_00228 2.75e-306 - - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HHEMLNNI_00229 6.89e-183 srtB 3.4.22.70 - S ko:K08600 - ko00000,ko01000,ko01002,ko01011 Sortase family
HHEMLNNI_00230 1.27e-174 fepC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_00231 2.34e-217 fhuB11 - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_00232 2.33e-209 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHEMLNNI_00233 0.0 - - - M - - - Cell surface protein
HHEMLNNI_00234 1.96e-156 isdC - - M - - - NEAr Transporter domain
HHEMLNNI_00235 2.94e-71 isdG 1.14.99.48 - C ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
HHEMLNNI_00236 4.73e-221 fhuG7 - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_00237 2.98e-219 fhuD11 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HHEMLNNI_00238 8.77e-286 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHEMLNNI_00239 1.24e-188 - - - S - - - Methyltransferase domain
HHEMLNNI_00240 1.52e-144 - - - K - - - Bacterial transcriptional repressor C-terminal
HHEMLNNI_00241 0.0 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HHEMLNNI_00242 4.12e-293 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HHEMLNNI_00243 5.26e-163 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HHEMLNNI_00244 1.4e-199 gltR3 - - K - - - LysR substrate binding domain
HHEMLNNI_00245 1.69e-232 - 3.8.1.3 - S ko:K01561 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha/beta hydrolase family
HHEMLNNI_00246 1.58e-200 - 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
HHEMLNNI_00247 2.85e-242 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HHEMLNNI_00248 1.36e-242 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_00249 1.57e-189 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00250 2.55e-219 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00251 4.41e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_00252 5.15e-289 - - - GK - - - ROK family
HHEMLNNI_00253 1.11e-282 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HHEMLNNI_00254 6.38e-86 yqiX - - S - - - YolD-like protein
HHEMLNNI_00256 3.02e-06 sda - - S ko:K06371 - ko00000 sporulation
HHEMLNNI_00257 0.0 - - - K - - - Mga helix-turn-helix domain
HHEMLNNI_00258 2.64e-63 - - - - - - - -
HHEMLNNI_00259 3.14e-113 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HHEMLNNI_00260 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HHEMLNNI_00261 0.0 - - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase
HHEMLNNI_00262 4.9e-22 - - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase
HHEMLNNI_00263 7.92e-253 dctP - - C - - - Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHEMLNNI_00264 0.0 - - - - - - - -
HHEMLNNI_00265 3.87e-219 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HHEMLNNI_00266 3.67e-227 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HHEMLNNI_00267 1.07e-160 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HHEMLNNI_00269 9.21e-212 - - - V - - - VanW like protein
HHEMLNNI_00270 1.99e-124 - - - V - - - (ABC) transporter
HHEMLNNI_00271 2.06e-61 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
HHEMLNNI_00272 6.33e-157 yqeB - - - - - - -
HHEMLNNI_00273 4.92e-136 - - - K - - - Bacterial regulatory proteins, tetR family
HHEMLNNI_00274 3.54e-193 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHEMLNNI_00275 0.0 - 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHEMLNNI_00276 1.46e-112 - 1.8.5.2 - S ko:K16937 ko00920,ko01120,map00920,map01120 ko00000,ko00001,ko01000 DoxX
HHEMLNNI_00277 1.14e-28 - - - - - - - -
HHEMLNNI_00278 1.73e-77 - - - - - - - -
HHEMLNNI_00279 1.94e-123 - - - K ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HHEMLNNI_00281 1.31e-197 - - - S ko:K07088 - ko00000 Membrane transport protein
HHEMLNNI_00282 1.36e-240 - - - G - - - Xylose isomerase
HHEMLNNI_00283 3.93e-184 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00284 1.78e-213 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00285 6.4e-301 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_00286 1.64e-237 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_00287 3.89e-242 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HHEMLNNI_00288 1.32e-80 - - - S - - - Ketosteroid isomerase-related protein
HHEMLNNI_00289 4.15e-187 - - - K - - - Helix-turn-helix domain
HHEMLNNI_00290 1.24e-231 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHEMLNNI_00291 7.49e-198 dkgB - - S - - - Aldo/keto reductase family
HHEMLNNI_00292 1.07e-241 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HHEMLNNI_00293 2.7e-312 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HHEMLNNI_00294 1.43e-177 - - - S - - - Nucleotidyltransferase domain
HHEMLNNI_00295 1.11e-197 - 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HHEMLNNI_00296 1.15e-163 - - - KT - - - Forkhead associated domain
HHEMLNNI_00297 7.13e-313 amaB_2 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHEMLNNI_00298 3.08e-204 yuiI - - S ko:K07017 - ko00000 Putative esterase
HHEMLNNI_00299 1.51e-236 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_00300 4.84e-234 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_00301 5.59e-224 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HHEMLNNI_00302 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HHEMLNNI_00304 8.69e-230 ectD 1.14.11.55 - Q ko:K10674 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Phytanoyl-CoA dioxygenase (PhyH)
HHEMLNNI_00305 6.1e-256 - - - - - - - -
HHEMLNNI_00306 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
HHEMLNNI_00307 5.78e-247 gerKB - - E - - - Spore germination protein
HHEMLNNI_00308 1.41e-264 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
HHEMLNNI_00309 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HHEMLNNI_00310 2.12e-175 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_00311 1.61e-299 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_00312 1.51e-154 msmF3 - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00313 2.47e-185 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HHEMLNNI_00314 0.0 - - - S - - - Chlorophyllase enzyme
HHEMLNNI_00315 2.7e-83 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHEMLNNI_00316 0.0 - - - GKT - - - Mga helix-turn-helix domain
HHEMLNNI_00317 5.67e-233 - 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHEMLNNI_00318 2.25e-60 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG3414 Phosphotransferase system, galactitol-specific IIB component
HHEMLNNI_00319 4.42e-274 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system ascorbate-specific transporter subunit IIC
HHEMLNNI_00320 1.34e-199 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HHEMLNNI_00321 7.71e-133 - 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HHEMLNNI_00322 3.01e-09 gsiB - - S ko:K06884 - ko00000 general stress protein
HHEMLNNI_00323 2.24e-201 - 2.1.1.184 - J ko:K00561 - br01600,ko00000,ko01000,ko01504,ko03009 Ribosomal RNA adenine dimethylases
HHEMLNNI_00324 3.71e-76 - - - S - - - Domain of unknown function (DUF4260)
HHEMLNNI_00325 1.01e-90 - - - K - - - helix_turn_helix, mercury resistance
HHEMLNNI_00326 1.83e-257 - 6.3.5.5 - S ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 ATP-grasp domain
HHEMLNNI_00327 9.2e-268 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
HHEMLNNI_00328 1.99e-131 - - - S - - - DinB superfamily
HHEMLNNI_00330 7.31e-167 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HHEMLNNI_00331 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HHEMLNNI_00332 4.31e-300 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HHEMLNNI_00333 1.01e-190 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HHEMLNNI_00334 1.01e-312 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HHEMLNNI_00335 2e-301 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HHEMLNNI_00336 4.52e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_00338 0.0 - - - - - - - -
HHEMLNNI_00339 0.0 - - - - - - - -
HHEMLNNI_00340 1.38e-194 yxxF - - EG - - - EamA-like transporter family
HHEMLNNI_00341 4.15e-191 - - - K - - - Transcriptional regulator
HHEMLNNI_00342 7.34e-142 - - - S - - - ABC-2 family transporter protein
HHEMLNNI_00343 4.86e-198 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HHEMLNNI_00344 1.57e-236 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_00345 5.72e-241 - - - E - - - Amidinotransferase
HHEMLNNI_00346 0.0 - - - E - - - Sodium:solute symporter family
HHEMLNNI_00347 2.79e-174 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HHEMLNNI_00348 5.64e-254 - - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HHEMLNNI_00349 3.2e-285 - - - S - - - Erythromycin esterase
HHEMLNNI_00350 1.94e-115 ykuD - - S - - - protein conserved in bacteria
HHEMLNNI_00351 6.73e-227 - - - S - - - Choline/ethanolamine kinase
HHEMLNNI_00352 6.66e-72 - - - - - - - -
HHEMLNNI_00353 0.0 - - - - - - - -
HHEMLNNI_00354 2.6e-152 - - - - - - - -
HHEMLNNI_00355 4.13e-81 - - - K - - - MerR, DNA binding
HHEMLNNI_00356 3.97e-191 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HHEMLNNI_00357 1.73e-93 - - - K - - - Transcriptional regulator
HHEMLNNI_00358 2.43e-100 - - - - - - - -
HHEMLNNI_00359 4.16e-208 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HHEMLNNI_00360 1.62e-206 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HHEMLNNI_00361 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HHEMLNNI_00362 2.58e-80 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HHEMLNNI_00363 1.15e-200 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHEMLNNI_00364 6.64e-233 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HHEMLNNI_00365 2.47e-223 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
HHEMLNNI_00367 2.98e-96 - - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
HHEMLNNI_00368 0.0 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HHEMLNNI_00369 1.63e-161 - - - T - - - Transcriptional regulatory protein, C terminal
HHEMLNNI_00370 1.47e-168 - - - - - - - -
HHEMLNNI_00371 1.04e-166 - - - S - - - ABC-2 family transporter protein
HHEMLNNI_00372 2.58e-166 pstB13 - - V - - - AAA domain, putative AbiEii toxin, Type IV TA system
HHEMLNNI_00373 7.94e-134 - - - H - - - Flavoprotein
HHEMLNNI_00374 0.0 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
HHEMLNNI_00375 0.0 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
HHEMLNNI_00377 1.43e-222 XK27_06795 - - K ko:K20391 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
HHEMLNNI_00378 0.0 yvcC1 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HHEMLNNI_00380 3.23e-127 - - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HHEMLNNI_00381 1.84e-314 bglC 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HHEMLNNI_00382 0.0 bglH - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_00384 1.04e-71 - - - K - - - Helix-turn-helix XRE-family like proteins
HHEMLNNI_00385 7.57e-135 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HHEMLNNI_00386 0.0 - - - M - - - cell wall anchor domain
HHEMLNNI_00387 9.34e-99 - - - T - - - Bacterial transcriptional activator domain
HHEMLNNI_00388 1.22e-259 - - - T - - - Histidine kinase
HHEMLNNI_00390 4.88e-227 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_00391 1.64e-251 rspA 4.2.1.8 - M ko:K08323 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HHEMLNNI_00392 1.64e-117 - - - K - - - Helix-turn-helix domain
HHEMLNNI_00393 2.51e-26 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHEMLNNI_00395 0.0 ramA 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase
HHEMLNNI_00396 3.34e-135 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00397 3.25e-150 - - - G - - - Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00398 2.86e-167 - - - G - - - Bacterial extracellular solute-binding protein
HHEMLNNI_00400 3.46e-48 - - - T - - - helix_turn_helix, arabinose operon control protein
HHEMLNNI_00401 9.2e-151 - - - T - - - Histidine kinase
HHEMLNNI_00402 6.66e-109 - - - S - - - Sulfite exporter TauE/SafE
HHEMLNNI_00403 6.27e-153 - - - K - - - Transcriptional regulator
HHEMLNNI_00404 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate synthase
HHEMLNNI_00405 7.48e-177 yoaT - - S - - - Protein of unknown function (DUF817)
HHEMLNNI_00406 1.49e-40 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_00407 1.8e-78 yoaS - - S - - - Protein of unknown function (DUF2975)
HHEMLNNI_00409 3.03e-153 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HHEMLNNI_00410 4.66e-198 kbaY 4.1.2.13, 4.1.2.40 - G ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
HHEMLNNI_00411 5.59e-249 - 1.1.1.14, 1.1.1.251 - C ko:K00008,ko:K00094 ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100 ko00000,ko00001,ko00002,ko01000 Alcohol dehydrogenase GroES-like domain
HHEMLNNI_00412 1.44e-311 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3775 Phosphotransferase system, galactitol-specific IIC component
HHEMLNNI_00413 6.76e-56 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG3414 Phosphotransferase system, galactitol-specific IIB component
HHEMLNNI_00414 2.78e-103 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHEMLNNI_00415 2.05e-183 - - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HHEMLNNI_00416 9.03e-229 lacC 2.7.1.144 - G ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HHEMLNNI_00417 3.58e-87 yqjY - - K ko:K06977 - ko00000 Acetyltransferase (GNAT) domain
HHEMLNNI_00418 1.5e-118 - - - S - - - Protein of unknown function with HXXEE motif
HHEMLNNI_00420 9.74e-108 - - - - - - - -
HHEMLNNI_00421 1.46e-99 - - - S - - - Protein of unknown function (DUF1648)
HHEMLNNI_00422 6.91e-180 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HHEMLNNI_00423 0.0 malP 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_00424 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHEMLNNI_00425 0.0 - - - C - - - FAD dependent oxidoreductase
HHEMLNNI_00426 2.69e-191 ugpE3 - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00427 1.22e-219 - - - U ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00428 1.82e-314 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_00429 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_00430 5e-173 - - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HHEMLNNI_00431 0.0 - - - G - - - beta-fructofuranosidase activity
HHEMLNNI_00432 1.11e-96 - - - L ko:K07451,ko:K07452 - ko00000,ko01000,ko02048 HNH endonuclease
HHEMLNNI_00433 2.19e-61 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHEMLNNI_00434 2.37e-250 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHEMLNNI_00435 1.13e-152 cas4 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 RecB family exonuclease
HHEMLNNI_00436 1.3e-202 csd2 - - L ko:K19115,ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
HHEMLNNI_00437 0.0 csd1 - - M ko:K19117 - ko00000,ko02048 CRISPR-associated protein (Cas_Csd1)
HHEMLNNI_00438 1.7e-178 cas5 - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
HHEMLNNI_00440 0.0 - - - L ko:K07012 - ko00000,ko01000,ko02048 Metal dependent phosphohydrolases with conserved 'HD' motif.
HHEMLNNI_00442 3.84e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HHEMLNNI_00443 0.0 - - - M - - - Belongs to the BCCT transporter (TC 2.A.15) family
HHEMLNNI_00445 4.47e-103 - - - S - - - yiaA/B two helix domain
HHEMLNNI_00446 1.27e-221 - 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Bacterial fructose-1,6-bisphosphatase, glpX-encoded
HHEMLNNI_00447 1.77e-144 - 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HHEMLNNI_00448 5.52e-241 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HHEMLNNI_00449 6.17e-104 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose/Galactose Isomerase
HHEMLNNI_00450 4.4e-172 - - - K - - - DeoR C terminal sensor domain
HHEMLNNI_00451 3.23e-173 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_00452 5.56e-270 - 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HHEMLNNI_00453 1.12e-303 yoaB - - EGP - - - the major facilitator superfamily
HHEMLNNI_00454 4.26e-69 - - - S ko:K07068 - ko00000 DUF35 OB-fold domain, acyl-CoA-associated
HHEMLNNI_00455 2.53e-265 - 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Thiolase, C-terminal domain
HHEMLNNI_00456 0.0 - 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHEMLNNI_00457 2.25e-118 - - - S - - - DNA-binding protein with PD1-like DNA-binding motif
HHEMLNNI_00458 1.1e-179 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HHEMLNNI_00459 9.26e-278 - - - G - - - Tripartite ATP-independent periplasmic transporter, DctM component
HHEMLNNI_00460 4.68e-110 - - - G ko:K11689 ko02020,map02020 ko00000,ko00001,ko02000 Tripartite ATP-independent periplasmic transporters, DctQ component
HHEMLNNI_00461 2.86e-245 - - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HHEMLNNI_00462 4.96e-172 - - - K ko:K19333 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_00463 3.29e-259 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HHEMLNNI_00466 5.2e-54 - - - S - - - Protein of unknown function (DUF2642)
HHEMLNNI_00467 3.39e-224 - - - P ko:K07217 - ko00000 Catalase
HHEMLNNI_00468 1.43e-217 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HHEMLNNI_00469 0.0 - - - F - - - Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HHEMLNNI_00470 8.86e-78 ydeP9 - - K - - - HxlR-like helix-turn-helix
HHEMLNNI_00471 1.47e-209 - - - S ko:K06911 - ko00000 Belongs to the pirin family
HHEMLNNI_00472 2.07e-203 ycnC - - K - - - Transcriptional regulator
HHEMLNNI_00473 1.3e-263 - - - S ko:K07148 - ko00000 Protein of unknown function (DUF418)
HHEMLNNI_00474 3.19e-37 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HHEMLNNI_00475 4.6e-95 - - - - - - - -
HHEMLNNI_00477 1.42e-47 - - - - - - - -
HHEMLNNI_00478 1.46e-150 - - - S - - - Putative adhesin
HHEMLNNI_00479 9.29e-157 - - - S - - - ABC-2 family transporter protein
HHEMLNNI_00480 4.56e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_00481 7.17e-172 - - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_00482 1.9e-257 - - - T - - - Histidine kinase
HHEMLNNI_00483 3.54e-199 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHEMLNNI_00484 3.66e-166 - - - S ko:K07010 - ko00000,ko01002 Peptidase C26
HHEMLNNI_00485 1.99e-260 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HHEMLNNI_00486 1.68e-177 - - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HHEMLNNI_00487 0.0 - - - T - - - Histidine kinase
HHEMLNNI_00488 0.0 sfuB - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00489 2.8e-255 fbpC 3.6.3.30 - P ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHEMLNNI_00490 6.46e-242 - - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_00492 2.08e-112 - - - - - - - -
HHEMLNNI_00493 4.94e-288 - - - S ko:K12941,ko:K21613 - ko00000,ko01000,ko01002 Peptidase dimerisation domain
HHEMLNNI_00494 2.54e-286 - - - S ko:K12941,ko:K21613 - ko00000,ko01000,ko01002 Peptidase dimerisation domain
HHEMLNNI_00495 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
HHEMLNNI_00496 9.96e-287 - - - E - - - Peptidase family M28
HHEMLNNI_00497 1.42e-247 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_00498 1.3e-236 - - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_00499 1.12e-214 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
HHEMLNNI_00500 1.5e-202 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00501 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HHEMLNNI_00503 8.88e-213 - - - K - - - Transcriptional regulator
HHEMLNNI_00504 2.02e-206 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HHEMLNNI_00505 6e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HHEMLNNI_00506 2.88e-69 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HHEMLNNI_00507 2.68e-67 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HHEMLNNI_00508 5e-292 celD 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHEMLNNI_00509 2.22e-61 - - - - - - - -
HHEMLNNI_00510 9.49e-317 - 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHEMLNNI_00511 1.31e-179 - - - S - - - CAAX protease self-immunity
HHEMLNNI_00512 2.28e-113 - - - S ko:K09167 - ko00000 Bacterial PH domain
HHEMLNNI_00513 0.0 - - - S ko:K08981 - ko00000 Bacterial PH domain
HHEMLNNI_00516 8.97e-08 - - - - - - - -
HHEMLNNI_00517 2.01e-140 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_00520 5.03e-91 ytcD - - K - - - Transcriptional regulator
HHEMLNNI_00521 2.34e-142 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HHEMLNNI_00522 8.14e-143 - - - K - - - intracellular protease amidase
HHEMLNNI_00524 2.08e-42 - - - S - - - Domain of unknown function (DUF3784)
HHEMLNNI_00525 6.84e-310 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHEMLNNI_00526 1.97e-99 cps1C - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHEMLNNI_00527 2.04e-63 - - - M - - - Glycosyltransferase like family 2
HHEMLNNI_00528 4.33e-14 - - - M - - - O-Antigen ligase
HHEMLNNI_00529 3.31e-134 - - - M - - - Glycosyl transferases group 1
HHEMLNNI_00530 2.11e-88 - - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HHEMLNNI_00531 1.19e-102 - - - GM - - - NAD(P)H-binding
HHEMLNNI_00532 5.2e-160 - - - F - - - ATP-grasp domain
HHEMLNNI_00533 2.52e-196 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HHEMLNNI_00534 1.88e-306 pglF - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HHEMLNNI_00535 4.48e-200 - 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HHEMLNNI_00536 8.01e-201 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHEMLNNI_00538 1.11e-229 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HHEMLNNI_00539 2.26e-266 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HHEMLNNI_00540 8.09e-241 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HHEMLNNI_00541 0.0 gerAA - - EG ko:K06288,ko:K06310 - ko00000 Spore germination protein
HHEMLNNI_00542 2.52e-28 - - - S - - - Nucleotidyltransferase domain
HHEMLNNI_00543 2.96e-50 - - - S - - - Nucleotidyltransferase substrate binding protein like
HHEMLNNI_00544 8.25e-248 - - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
HHEMLNNI_00545 7.5e-132 - - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
HHEMLNNI_00546 7.66e-39 - - - S - - - Domain of unknown function (DUF5082)
HHEMLNNI_00547 1.34e-59 - - - - - - - -
HHEMLNNI_00550 1.05e-64 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_00551 3.01e-23 - - - S - - - Family of unknown function (DUF5344)
HHEMLNNI_00552 1.27e-102 - - - S - - - Bacterial PH domain
HHEMLNNI_00553 1.23e-172 ycdF 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Short-chain dehydrogenase reductase sdr
HHEMLNNI_00554 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HHEMLNNI_00555 1.06e-155 mdmC1 - - S - - - O-methyltransferase
HHEMLNNI_00556 4.74e-212 - - - K - - - LysR substrate binding domain
HHEMLNNI_00557 4.59e-58 sdpR - - K - - - transcriptional
HHEMLNNI_00558 4e-147 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HHEMLNNI_00559 9.08e-181 - - - G - - - Phosphoenolpyruvate phosphomutase
HHEMLNNI_00561 1.53e-206 - - - E - - - Glyoxalase-like domain
HHEMLNNI_00562 3.37e-236 - - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHEMLNNI_00563 2.58e-178 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHEMLNNI_00564 5.38e-167 ssuB - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HHEMLNNI_00566 1.2e-151 lin0465 - - S - - - DJ-1/PfpI family
HHEMLNNI_00567 4.35e-198 - - - K ko:K13572 - ko00000,ko03051 transcriptional regulator
HHEMLNNI_00568 6.65e-195 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HHEMLNNI_00569 6.72e-123 - - - K - - - Acetyltransferase (GNAT) domain
HHEMLNNI_00570 2.21e-180 - - - S - - - Alpha/beta hydrolase family
HHEMLNNI_00571 1.16e-48 - - - GM - - - NAD dependent epimerase/dehydratase family
HHEMLNNI_00572 2.75e-61 - - - GM - - - NAD dependent epimerase/dehydratase family
HHEMLNNI_00574 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
HHEMLNNI_00576 5.84e-294 - - - S - - - Putative esterase
HHEMLNNI_00577 4.71e-119 yvdQ - - S - - - Protein of unknown function (DUF3231)
HHEMLNNI_00578 3.03e-63 ycbP - - S - - - Protein of unknown function (DUF2512)
HHEMLNNI_00579 2.41e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HHEMLNNI_00581 7.69e-276 - 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HHEMLNNI_00582 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HHEMLNNI_00583 0.0 - - - S - - - Membrane
HHEMLNNI_00584 3.36e-77 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HHEMLNNI_00585 4.91e-233 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HHEMLNNI_00586 5.96e-117 - - - S - - - OHCU decarboxylase
HHEMLNNI_00587 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HHEMLNNI_00588 4.49e-298 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHEMLNNI_00589 3.62e-310 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HHEMLNNI_00590 1.63e-119 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HHEMLNNI_00591 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HHEMLNNI_00592 9.96e-213 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HHEMLNNI_00593 5.06e-137 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HHEMLNNI_00594 2.93e-235 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HHEMLNNI_00595 8.13e-238 - - - P - - - COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HHEMLNNI_00596 8.84e-186 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00597 3.8e-180 - - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HHEMLNNI_00598 1.33e-240 - - - P - - - NMT1-like family
HHEMLNNI_00599 1.49e-194 - - - P ko:K02050,ko:K15552 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00600 2.39e-178 - - - P ko:K02049 - ko00000,ko00002,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HHEMLNNI_00601 0.0 fhuB5 - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_00602 1.76e-234 cbrA5 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Ferrichrome ABC transporter substrate-binding protein
HHEMLNNI_00603 4.57e-90 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HHEMLNNI_00604 2.24e-106 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HHEMLNNI_00605 1.71e-105 - - - S - - - ASCH
HHEMLNNI_00606 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
HHEMLNNI_00607 1.44e-197 - - - I - - - Domain of unknown function (DUF1932)
HHEMLNNI_00608 1.7e-199 - - - K - - - Helix-turn-helix domain, rpiR family
HHEMLNNI_00609 4.34e-151 - 4.1.3.17 - H ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 ko00000,ko00001,ko01000 Methyltransferase
HHEMLNNI_00610 3.87e-42 - - - - - - - -
HHEMLNNI_00611 7.09e-308 - - - G - - - Tripartite ATP-independent periplasmic transporter, DctM component
HHEMLNNI_00612 1.37e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HHEMLNNI_00613 6.63e-232 - - - K - - - Transcriptional regulator
HHEMLNNI_00614 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_00615 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HHEMLNNI_00616 1.29e-234 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HHEMLNNI_00617 4.87e-148 ydgI - - C - - - nitroreductase
HHEMLNNI_00618 2.1e-78 - - - K - - - helix_turn_helix, mercury resistance
HHEMLNNI_00619 2.19e-121 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HHEMLNNI_00620 3.67e-177 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HHEMLNNI_00621 1.3e-266 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HHEMLNNI_00622 3.73e-240 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HHEMLNNI_00623 2.06e-177 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HHEMLNNI_00624 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_00625 1.87e-220 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00626 7.25e-206 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_00627 1.45e-178 - - - K - - - helix_turn_helix, mercury resistance
HHEMLNNI_00628 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HHEMLNNI_00629 2.93e-108 - - - - - - - -
HHEMLNNI_00630 0.0 gltD 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HHEMLNNI_00631 1.64e-300 preA 1.3.1.1 - CF ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 dihydroorotate dehydrogenase
HHEMLNNI_00632 0.0 hydA 3.5.2.2 - F ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Amidohydrolase family
HHEMLNNI_00634 6.68e-302 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHEMLNNI_00635 0.0 - - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHEMLNNI_00636 3.71e-100 - - - F - - - PFAM AIG2 family protein
HHEMLNNI_00637 9.42e-149 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HHEMLNNI_00638 2.21e-94 - - - K - - - Transcriptional regulator
HHEMLNNI_00640 0.0 bglP11 - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_00641 9.79e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HHEMLNNI_00642 0.0 bglH7 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HHEMLNNI_00643 1.44e-38 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
HHEMLNNI_00644 1.77e-17 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
HHEMLNNI_00645 4.89e-51 - - - L - - - transposase activity
HHEMLNNI_00646 1.7e-70 - - - - - - - -
HHEMLNNI_00647 3.71e-301 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_00648 2.83e-53 - - - S - - - Family of unknown function (DUF5344)
HHEMLNNI_00649 3.52e-45 - - - S - - - Domain of unknown function (DUF5082)
HHEMLNNI_00652 3.96e-238 - - - S - - - Tetratricopeptide repeat
HHEMLNNI_00653 0.0 - - - T - - - Domain present in phytochromes and cGMP-specific phosphodiesterases.
HHEMLNNI_00654 0.0 - - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHEMLNNI_00655 1.11e-202 - 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HHEMLNNI_00656 3.64e-178 - - - S - - - Protein of unknown function (DUF3100)
HHEMLNNI_00657 9.16e-95 - - - S - - - An automated process has identified a potential problem with this gene model
HHEMLNNI_00658 1.75e-181 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HHEMLNNI_00659 3.66e-157 epsB 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HHEMLNNI_00660 1.08e-150 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HHEMLNNI_00661 2.99e-219 tagU - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HHEMLNNI_00662 7.94e-109 - - - S - - - Tetratrico peptide repeat
HHEMLNNI_00663 1.1e-112 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HHEMLNNI_00664 1.14e-101 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
HHEMLNNI_00665 9.58e-286 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HHEMLNNI_00666 6.27e-248 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HHEMLNNI_00667 4.93e-215 tagU - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HHEMLNNI_00668 2.02e-61 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HHEMLNNI_00669 7.42e-296 - - - - - - - -
HHEMLNNI_00670 1.47e-305 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHEMLNNI_00671 4.49e-297 lytE - - M - - - NlpC/P60 family
HHEMLNNI_00672 1.99e-194 - - - Q - - - N-acetyltransferase
HHEMLNNI_00673 1.09e-107 yisT - - S - - - DinB family
HHEMLNNI_00674 7.16e-127 - - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHEMLNNI_00675 0.0 pip - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HHEMLNNI_00676 1.09e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHEMLNNI_00677 1.02e-187 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
HHEMLNNI_00678 1.52e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HHEMLNNI_00679 1.27e-248 - - - S ko:K06308 - ko00000 Spore germination B3/ GerAC like, C-terminal
HHEMLNNI_00680 1.62e-255 - - - E - - - Spore germination protein
HHEMLNNI_00681 0.0 - - - P - - - Spore gernimation protein GerA
HHEMLNNI_00682 4.62e-81 - - - S - - - DNA-directed RNA polymerase subunit beta
HHEMLNNI_00683 4.13e-183 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HHEMLNNI_00684 2.58e-183 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HHEMLNNI_00685 1.9e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HHEMLNNI_00686 1.68e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HHEMLNNI_00687 2.02e-63 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HHEMLNNI_00688 1.25e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HHEMLNNI_00689 1.07e-181 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HHEMLNNI_00690 5.11e-242 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HHEMLNNI_00691 1.92e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHEMLNNI_00692 1.66e-21 ywmB - - S - - - TATA-box binding
HHEMLNNI_00693 2.09e-81 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HHEMLNNI_00694 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHEMLNNI_00695 3.39e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHEMLNNI_00696 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHEMLNNI_00697 4.1e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHEMLNNI_00698 2.37e-47 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHEMLNNI_00699 2.78e-28 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHEMLNNI_00700 3.41e-170 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HHEMLNNI_00701 1.25e-10 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase I chain
HHEMLNNI_00702 1.61e-44 - - - S - - - Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
HHEMLNNI_00703 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HHEMLNNI_00704 1.1e-117 panZ - - K - - - -acetyltransferase
HHEMLNNI_00705 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHEMLNNI_00706 1.07e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHEMLNNI_00707 3.26e-124 ywlG - - S - - - Belongs to the UPF0340 family
HHEMLNNI_00708 3.9e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HHEMLNNI_00709 4.11e-248 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Chemotaxis
HHEMLNNI_00710 4.11e-95 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHEMLNNI_00711 2.39e-121 mntP - - P - - - Probably functions as a manganese efflux pump
HHEMLNNI_00712 4.54e-77 - - - S - - - Regulator of ribonuclease activity B
HHEMLNNI_00713 3.2e-233 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHEMLNNI_00714 1.36e-96 ywlB 1.20.4.1, 2.3.1.1 - E ko:K00537,ko:K00619 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetyltransferase family. ArgA subfamily
HHEMLNNI_00715 7.81e-148 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HHEMLNNI_00716 2.17e-207 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHEMLNNI_00717 1.55e-232 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHEMLNNI_00718 0.0 cdr 1.11.1.1 - P ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HHEMLNNI_00719 1.19e-97 - - - - - - - -
HHEMLNNI_00720 1.88e-142 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HHEMLNNI_00721 2.08e-54 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HHEMLNNI_00722 2.94e-300 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HHEMLNNI_00723 3.67e-227 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HHEMLNNI_00724 2e-285 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHEMLNNI_00725 2.81e-149 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHEMLNNI_00726 3.32e-206 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HHEMLNNI_00727 1.27e-78 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
HHEMLNNI_00728 1.77e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
HHEMLNNI_00729 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHEMLNNI_00730 2.77e-94 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHEMLNNI_00731 4.32e-140 kstR2_2 - - K - - - Transcriptional regulator
HHEMLNNI_00732 2.72e-261 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HHEMLNNI_00733 5.91e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HHEMLNNI_00734 5.42e-275 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
HHEMLNNI_00735 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HHEMLNNI_00736 6.63e-278 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HHEMLNNI_00737 3.78e-96 - - - S ko:K09793 - ko00000 protein conserved in bacteria
HHEMLNNI_00738 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HHEMLNNI_00739 1.89e-100 ywiB - - S - - - protein conserved in bacteria
HHEMLNNI_00740 2.02e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HHEMLNNI_00741 8.83e-205 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HHEMLNNI_00742 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HHEMLNNI_00743 1.15e-199 - - - K - - - Acetyltransferase (GNAT) domain
HHEMLNNI_00744 0.0 - - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HHEMLNNI_00745 6.82e-128 ywhD - - S - - - YwhD family
HHEMLNNI_00746 3.98e-257 - - - F - - - S-adenosylhomocysteine deaminase activity
HHEMLNNI_00747 5.89e-161 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HHEMLNNI_00748 5.91e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HHEMLNNI_00750 8.17e-119 ywgA - - - ko:K09388 - ko00000 -
HHEMLNNI_00751 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HHEMLNNI_00752 4.6e-273 gltP - - C - - - Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHEMLNNI_00753 1.91e-194 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HHEMLNNI_00754 3.69e-232 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HHEMLNNI_00755 3.84e-183 - 5.3.3.18 - I ko:K15866 ko00360,ko01120,map00360,map01120 ko00000,ko00001,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HHEMLNNI_00756 3.86e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HHEMLNNI_00757 2.12e-182 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHEMLNNI_00758 3.16e-64 - - - - - - - -
HHEMLNNI_00759 4.29e-252 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HHEMLNNI_00760 5.34e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_00761 8.83e-209 natA1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HHEMLNNI_00762 9.31e-84 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HHEMLNNI_00763 1.38e-167 - - - - - - - -
HHEMLNNI_00764 1.38e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HHEMLNNI_00765 8.65e-107 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HHEMLNNI_00766 4.91e-78 ywdK - - S - - - small membrane protein
HHEMLNNI_00767 1.71e-144 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHEMLNNI_00768 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHEMLNNI_00769 4.39e-62 - - - S - - - Family of unknown function (DUF5327)
HHEMLNNI_00770 9.46e-175 polC1 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
HHEMLNNI_00771 2.35e-218 - - - T ko:K07182 - ko00000 Putative nucleotidyltransferase substrate binding domain
HHEMLNNI_00772 1.68e-295 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HHEMLNNI_00773 3.61e-226 - - - S ko:K07120 - ko00000 Pfam:AmoA
HHEMLNNI_00774 1.7e-176 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHEMLNNI_00775 8.71e-305 - - - S - - - protein conserved in bacteria
HHEMLNNI_00776 1.29e-190 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HHEMLNNI_00777 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
HHEMLNNI_00778 5.89e-63 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HHEMLNNI_00779 1.73e-161 - - - E - - - AzlC protein
HHEMLNNI_00780 0.0 gntR9 - - K - - - Alanine-glyoxylate amino-transferase
HHEMLNNI_00781 3.4e-164 XK27_07210 - - S - - - B3/4 domain
HHEMLNNI_00782 2.5e-300 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 methionine gamma-lyase
HHEMLNNI_00783 2.64e-244 - - - I - - - Fatty acid desaturase
HHEMLNNI_00784 0.0 - 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamine synthetase, catalytic domain
HHEMLNNI_00785 2.3e-101 - - - S - - - Protein of unknown function (DUF4064)
HHEMLNNI_00786 1.28e-112 - - - K - - - Acetyltransferase (GNAT) domain
HHEMLNNI_00787 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHEMLNNI_00788 4.32e-105 bdbA - - CO - - - Thioredoxin
HHEMLNNI_00789 5.29e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HHEMLNNI_00790 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HHEMLNNI_00792 1.97e-107 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HHEMLNNI_00793 2.44e-243 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HHEMLNNI_00794 5.22e-174 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HHEMLNNI_00795 4.21e-156 ydbC - - G - - - Domain of unknown function (DUF4937
HHEMLNNI_00796 6.38e-314 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HHEMLNNI_00797 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHEMLNNI_00798 1.48e-291 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HHEMLNNI_00799 2.81e-57 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HHEMLNNI_00800 7.27e-73 yflT - - S - - - Heat induced stress protein YflT
HHEMLNNI_00801 2.48e-129 - - - S - - - UPF0302 domain
HHEMLNNI_00802 1.37e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HHEMLNNI_00803 3.98e-205 XK27_03890 - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HHEMLNNI_00804 4.85e-181 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HHEMLNNI_00805 4.61e-224 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HHEMLNNI_00806 8.38e-189 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HHEMLNNI_00807 0.0 dapE - - E - - - Peptidase dimerisation domain
HHEMLNNI_00808 5.54e-289 - - - S - - - Acetyltransferase
HHEMLNNI_00809 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HHEMLNNI_00810 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHEMLNNI_00811 4.29e-275 yxlH - - EGP - - - Major Facilitator Superfamily
HHEMLNNI_00812 1.37e-182 - - - CG ko:K11055 - ko00000 glycosyl
HHEMLNNI_00813 1.32e-253 - - - E - - - Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HHEMLNNI_00814 5.48e-185 - 2.1.1.72 - J ko:K00571 - ko00000,ko01000,ko02048 protein-(glutamine-N5) methyltransferase activity
HHEMLNNI_00815 1.74e-122 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HHEMLNNI_00816 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter permease protein
HHEMLNNI_00817 1.42e-217 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHEMLNNI_00818 7.19e-65 acpT 2.7.8.7 - H ko:K00997,ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 lysine biosynthetic process via aminoadipic acid
HHEMLNNI_00819 1.09e-127 - - - S - - - DinB superfamily
HHEMLNNI_00820 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HHEMLNNI_00821 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HHEMLNNI_00822 8.94e-221 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HHEMLNNI_00823 1.06e-139 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHEMLNNI_00824 4.47e-146 yrbG - - S - - - membrane
HHEMLNNI_00825 1.59e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHEMLNNI_00828 4.79e-175 - - - K - - - TipAS antibiotic-recognition domain
HHEMLNNI_00829 3.1e-217 - - - O - - - Predicted Zn-dependent protease (DUF2268)
HHEMLNNI_00830 2.08e-138 - - - K - - - GrpB protein
HHEMLNNI_00831 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHEMLNNI_00832 6.72e-97 - - - L - - - Bacterial transcription activator, effector binding domain
HHEMLNNI_00833 1.79e-120 - - - - - - - -
HHEMLNNI_00834 1.48e-155 - - - - - - - -
HHEMLNNI_00835 4.23e-141 - - - - - - - -
HHEMLNNI_00836 0.0 - - - - - - - -
HHEMLNNI_00837 9.78e-89 - - - - - - - -
HHEMLNNI_00838 2.75e-91 - - - - - - - -
HHEMLNNI_00839 1.1e-178 - - - S - - - GNAT acetyltransferase
HHEMLNNI_00840 7.44e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHEMLNNI_00842 5.86e-312 - - - M - - - Peptidoglycan-binding domain 1 protein
HHEMLNNI_00844 0.0 - - - T - - - Histidine kinase
HHEMLNNI_00846 0.0 - - - - - - - -
HHEMLNNI_00847 1.76e-154 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HHEMLNNI_00848 0.0 sdcS - - P ko:K14445 - ko00000,ko02000 Sodium:sulfate symporter transmembrane region
HHEMLNNI_00849 9.65e-157 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HHEMLNNI_00850 0.0 - 2.7.13.3 - T ko:K02476,ko:K11614,ko:K11637 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HHEMLNNI_00851 8.46e-153 M1-740 - - I - - - COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HHEMLNNI_00852 2.58e-226 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HHEMLNNI_00853 9.88e-82 - - - S - - - CHY zinc finger
HHEMLNNI_00854 4.21e-302 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HHEMLNNI_00857 6.19e-55 sdpI - - S - - - integral membrane protein
HHEMLNNI_00858 4.91e-284 - - - EGP - - - Transmembrane secretion effector
HHEMLNNI_00859 3.51e-131 - - - S ko:K09962 - ko00000 protein conserved in bacteria
HHEMLNNI_00860 5.9e-54 ubiE - - Q - - - Methyltransferase type 11
HHEMLNNI_00861 5.29e-97 ubiE - - Q - - - Methyltransferase type 11
HHEMLNNI_00862 2.35e-303 - - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHEMLNNI_00863 1.32e-61 phhB 3.5.4.33, 4.2.1.96 - H ko:K01724,ko:K11991 ko00790,map00790 ko00000,ko00001,ko01000,ko03016,ko04147 pterin-4-alpha-carbinolamine dehydratase
HHEMLNNI_00864 7.69e-87 eaeH - - M ko:K13735 ko05100,map05100 ko00000,ko00001 LysM domain
HHEMLNNI_00865 2.58e-93 - - - S - - - YtkA-like
HHEMLNNI_00866 0.0 - - - T - - - Histidine kinase
HHEMLNNI_00867 1.75e-157 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_00868 4.12e-228 - - - S - - - amine dehydrogenase activity
HHEMLNNI_00869 2.26e-249 - - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HHEMLNNI_00871 1.98e-44 - - - - - - - -
HHEMLNNI_00872 5.33e-67 - - - S - - - Bacterial PH domain
HHEMLNNI_00873 3.06e-40 - - - - - - - -
HHEMLNNI_00874 3.27e-14 - - - - - - - -
HHEMLNNI_00875 1.06e-138 M1-1017 - - S - - - Protein of unknown function (DUF1129)
HHEMLNNI_00876 4.42e-73 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_00877 2.72e-135 - - - S - - - DUF218 domain
HHEMLNNI_00878 3.25e-190 degV - - S - - - protein conserved in bacteria
HHEMLNNI_00879 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHEMLNNI_00880 1.33e-52 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHEMLNNI_00881 6.22e-286 yciC - - S - - - GTPases (G3E family)
HHEMLNNI_00882 4.46e-165 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HHEMLNNI_00883 2.04e-12 - - - L - - - COG3666 Transposase and inactivated derivatives
HHEMLNNI_00885 3.32e-29 - - - K - - - Transcriptional regulator PadR-like family
HHEMLNNI_00886 5.51e-240 mhqA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HHEMLNNI_00887 0.0 - 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182 ko00130,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the UbiD family
HHEMLNNI_00888 1.51e-147 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HHEMLNNI_00889 1.29e-169 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HHEMLNNI_00890 3.11e-306 atoE - - I ko:K02106 ko02020,map02020 ko00000,ko00001 Short chain fatty acid transporter
HHEMLNNI_00891 5.52e-241 malR - - K - - - Transcriptional regulator
HHEMLNNI_00892 2.79e-190 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HHEMLNNI_00893 0.0 - - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HHEMLNNI_00894 2.99e-308 malE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HHEMLNNI_00895 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HHEMLNNI_00897 4.61e-312 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
HHEMLNNI_00898 1.25e-284 codB - - F ko:K10974 - ko00000,ko02000 cytosine purines uracil thiamine allantoin
HHEMLNNI_00900 0.0 - - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HHEMLNNI_00901 1.04e-289 lhgO 1.1.5.3 - S ko:K00111,ko:K15736 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
HHEMLNNI_00902 8.96e-283 - - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HHEMLNNI_00903 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HHEMLNNI_00904 1.66e-158 - - - K - - - COG2186 Transcriptional regulators
HHEMLNNI_00905 1.26e-155 - - - K ko:K05799 - ko00000,ko03000 FCD
HHEMLNNI_00906 0.0 - - - S - - - Tripartite ATP-independent periplasmic transporter, DctM component
HHEMLNNI_00907 4.18e-237 - - - S ko:K07080 - ko00000 NMT1-like family
HHEMLNNI_00908 1.3e-205 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_00909 2.41e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HHEMLNNI_00910 8.5e-271 - - - G - - - COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HHEMLNNI_00911 2.99e-98 - - - G - - - Tripartite ATP-independent periplasmic transporters, DctQ component
HHEMLNNI_00912 1.02e-236 - - - G - - - Bacterial extracellular solute-binding protein, family 7
HHEMLNNI_00913 2.11e-149 kdgR - - K - - - FCD
HHEMLNNI_00914 5.6e-250 yjmC 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HHEMLNNI_00915 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HHEMLNNI_00916 2.55e-116 - - - K - - - Acetyltransferase (GNAT) domain
HHEMLNNI_00917 1.19e-125 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HHEMLNNI_00918 6.1e-232 - - - S - - - Domain of unknown function (DUF4179)
HHEMLNNI_00919 4.83e-98 - - - S - - - Domain of unknown function (DU1801)
HHEMLNNI_00920 9.91e-150 - - - S - - - CGNR zinc finger
HHEMLNNI_00921 4.7e-108 - - - - - - - -
HHEMLNNI_00922 4.74e-21 - - - K ko:K07729 - ko00000,ko03000 transcriptional
HHEMLNNI_00924 0.0 - - - T - - - Carbon starvation protein
HHEMLNNI_00925 2.58e-173 - - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HHEMLNNI_00926 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_00927 1.26e-136 - - - K - - - Transcriptional regulator
HHEMLNNI_00928 0.0 ydfJ - - S ko:K07003 - ko00000 MMPL family
HHEMLNNI_00929 5.04e-262 - - - S - - - domain protein
HHEMLNNI_00930 5.07e-235 oppF3 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_00931 8.01e-229 oppD3 - - P ko:K02031,ko:K16202 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_00932 3.59e-212 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_00933 1.54e-222 appB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_00934 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HHEMLNNI_00935 4.2e-12 - - - - - - - -
HHEMLNNI_00936 3.61e-175 - - - S - - - Sulfite exporter TauE/SafE
HHEMLNNI_00937 6.95e-07 - - - - - - - -
HHEMLNNI_00939 2.46e-140 - - - S - - - ABC-2 family transporter protein
HHEMLNNI_00940 1.38e-191 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HHEMLNNI_00942 4.51e-156 - - - G - - - Class II Aldolase and Adducin N-terminal domain
HHEMLNNI_00943 1.03e-269 - - - G - - - COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HHEMLNNI_00944 1.83e-101 - - - G - - - Tripartite ATP-independent periplasmic transporters, DctQ component
HHEMLNNI_00945 4.88e-236 - - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HHEMLNNI_00946 1.63e-237 tdh 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HHEMLNNI_00947 6.95e-141 - - - K - - - FCD domain
HHEMLNNI_00948 3.5e-306 - 2.7.1.219, 2.7.1.220 - S ko:K22129 - ko00000,ko01000 Putative nucleotide-binding of sugar-metabolising enzyme
HHEMLNNI_00949 5.94e-183 - - - S - - - p-loop domain protein
HHEMLNNI_00950 6.42e-60 - - - L - - - Transposase IS116 IS110 IS902
HHEMLNNI_00951 2.17e-105 - - - L ko:K07486 - ko00000 COG3547 Transposase and inactivated derivatives
HHEMLNNI_00952 2.38e-76 - - - L - - - Uncharacterized conserved protein (DUF2075)
HHEMLNNI_00953 8.87e-47 - - - S - - - FRG domain
HHEMLNNI_00954 2.04e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHEMLNNI_00955 6.79e-12 - - - S - - - YyzF-like protein
HHEMLNNI_00956 8.9e-271 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHEMLNNI_00957 3.29e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HHEMLNNI_00958 2.27e-214 yycI - - S - - - protein conserved in bacteria
HHEMLNNI_00959 0.0 yycH - - S - - - protein conserved in bacteria
HHEMLNNI_00960 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_00961 7.17e-171 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_00967 1.94e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHEMLNNI_00968 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HHEMLNNI_00969 1.71e-89 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HHEMLNNI_00970 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HHEMLNNI_00971 7.84e-191 yybS - - S - - - membrane
HHEMLNNI_00972 4.32e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHEMLNNI_00973 4.35e-92 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHEMLNNI_00974 3.39e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HHEMLNNI_00975 6.91e-247 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHEMLNNI_00976 1.19e-37 yyzM - - S - - - protein conserved in bacteria
HHEMLNNI_00977 8.74e-223 yyaD - - S - - - Membrane
HHEMLNNI_00978 7.22e-149 yyaC - - S - - - Sporulation protein YyaC
HHEMLNNI_00979 9.75e-277 - - - E - - - Aminotransferase class-V
HHEMLNNI_00980 3.01e-194 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HHEMLNNI_00981 2.04e-174 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HHEMLNNI_00982 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HHEMLNNI_00983 7.14e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HHEMLNNI_00984 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHEMLNNI_00985 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHEMLNNI_00987 2.51e-145 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HHEMLNNI_00988 7.48e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHEMLNNI_00989 8.89e-80 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHEMLNNI_00990 2.52e-22 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HHEMLNNI_00991 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHEMLNNI_00992 4.21e-265 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHEMLNNI_00993 9.82e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HHEMLNNI_00994 1.98e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHEMLNNI_00995 2.79e-11 yqbO1 - - S - - - Domain of unknown function (DUF370)
HHEMLNNI_00996 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHEMLNNI_00997 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHEMLNNI_00998 7.79e-236 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_00999 1.98e-127 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Bacitracin ABC transporter permease
HHEMLNNI_01000 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HHEMLNNI_01001 1.86e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHEMLNNI_01002 1.3e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHEMLNNI_01003 1.54e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHEMLNNI_01004 1.5e-191 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HHEMLNNI_01005 1.51e-198 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HHEMLNNI_01006 2.26e-141 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HHEMLNNI_01007 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHEMLNNI_01008 1.13e-221 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HHEMLNNI_01009 1.07e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHEMLNNI_01010 3.69e-183 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HHEMLNNI_01011 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHEMLNNI_01012 2.21e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HHEMLNNI_01013 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHEMLNNI_01014 2.43e-225 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HHEMLNNI_01015 2.67e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HHEMLNNI_01016 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HHEMLNNI_01017 2.07e-284 citM - - C ko:K03300 - ko00000 Citrate transporter
HHEMLNNI_01019 7.4e-93 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HHEMLNNI_01020 1.73e-80 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HHEMLNNI_01021 1.33e-94 yabQ - - S - - - spore cortex biosynthesis protein
HHEMLNNI_01022 6.77e-71 yabP - - S - - - Sporulation protein YabP
HHEMLNNI_01023 1.15e-133 - - - S - - - SNARE associated Golgi protein
HHEMLNNI_01024 5.82e-255 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HHEMLNNI_01025 1.12e-114 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHEMLNNI_01026 3.01e-226 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHEMLNNI_01027 1.02e-153 yhcW - - S ko:K07025 - ko00000 hydrolase
HHEMLNNI_01028 2.69e-43 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HHEMLNNI_01029 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HHEMLNNI_01030 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHEMLNNI_01031 9.82e-116 - - - S - - - Yip1 domain
HHEMLNNI_01032 3.02e-254 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHEMLNNI_01033 1.66e-136 - - - S - - - Yip1 domain
HHEMLNNI_01034 2.3e-123 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HHEMLNNI_01035 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHEMLNNI_01036 7.35e-53 yabK - - S - - - Peptide ABC transporter permease
HHEMLNNI_01037 7.69e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHEMLNNI_01038 1.95e-141 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HHEMLNNI_01039 6.02e-219 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHEMLNNI_01040 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHEMLNNI_01041 2.26e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HHEMLNNI_01042 5.77e-81 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HHEMLNNI_01043 2.69e-191 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HHEMLNNI_01044 2.35e-211 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HHEMLNNI_01045 1.8e-34 sspF - - S ko:K06423 - ko00000 DNA topological change
HHEMLNNI_01046 4.02e-53 veg - - S - - - protein conserved in bacteria
HHEMLNNI_01047 4.38e-209 yabG - - S ko:K06436 - ko00000 peptidase
HHEMLNNI_01048 4.15e-202 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHEMLNNI_01049 9.52e-149 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHEMLNNI_01050 2.23e-285 yabE - - T - - - protein conserved in bacteria
HHEMLNNI_01051 6.64e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HHEMLNNI_01052 0.0 - - - S - - - Protein of unknown function (DUF3298)
HHEMLNNI_01053 7.76e-152 - - - T - - - protein histidine kinase activity
HHEMLNNI_01054 0.0 - - - S - - - ABC transporter
HHEMLNNI_01056 3.49e-239 pelB 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Amb_all
HHEMLNNI_01057 4.17e-107 - - - K - - - DNA-binding transcription factor activity
HHEMLNNI_01058 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHEMLNNI_01059 0.0 - - - S ko:K06915 - ko00000 Domain of unknown function DUF87
HHEMLNNI_01060 2.12e-225 - - - S - - - NurA
HHEMLNNI_01061 3.04e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HHEMLNNI_01062 1.2e-204 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHEMLNNI_01063 1.29e-58 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HHEMLNNI_01064 1.14e-175 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HHEMLNNI_01065 2.97e-60 yabA - - L - - - Involved in initiation control of chromosome replication
HHEMLNNI_01066 3.66e-188 yaaT - - S - - - stage 0 sporulation protein
HHEMLNNI_01067 3.03e-233 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HHEMLNNI_01068 1.19e-71 yaaQ - - S - - - protein conserved in bacteria
HHEMLNNI_01069 2.23e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHEMLNNI_01070 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HHEMLNNI_01072 1.15e-235 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HHEMLNNI_01073 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HHEMLNNI_01074 1.5e-256 adhA 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HHEMLNNI_01075 0.0 - - - T ko:K02481 - ko00000,ko02022 Sigma-54 interaction domain
HHEMLNNI_01076 0.0 cckA 2.7.13.3 - T ko:K02482 - ko00000,ko01000,ko01001,ko02022 GAF domain
HHEMLNNI_01077 7.96e-19 - - - - - - - -
HHEMLNNI_01078 1.41e-266 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 alcohol dehydrogenase
HHEMLNNI_01079 2.51e-46 - - - - - - - -
HHEMLNNI_01080 3.05e-185 pdaB - - G - - - Polysaccharide deacetylase
HHEMLNNI_01081 1.68e-131 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HHEMLNNI_01082 6.68e-96 gerD - - S ko:K06294 - ko00000 Spore gernimation protein
HHEMLNNI_01083 8.19e-134 - - - - - - - -
HHEMLNNI_01084 1.61e-225 - - - - - - - -
HHEMLNNI_01085 2.06e-130 - - - S - - - Sporulation delaying protein SdpA
HHEMLNNI_01086 7.65e-101 - - - S - - - Bacterial PH domain
HHEMLNNI_01087 1.37e-248 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HHEMLNNI_01088 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_01089 2.06e-196 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HHEMLNNI_01090 1.5e-171 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HHEMLNNI_01091 1.49e-104 ybaK - - S - - - Protein of unknown function (DUF2521)
HHEMLNNI_01092 0.000234 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHEMLNNI_01094 8.89e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_01095 1.32e-107 - - - S - - - Protein of unknown function (DUF2975)
HHEMLNNI_01096 4.45e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HHEMLNNI_01097 2.77e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHEMLNNI_01098 8.73e-189 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHEMLNNI_01099 4.75e-174 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHEMLNNI_01100 9.07e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHEMLNNI_01101 3.59e-207 cbiO - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHEMLNNI_01102 3.65e-78 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HHEMLNNI_01103 4.06e-216 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHEMLNNI_01104 4.05e-85 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHEMLNNI_01105 8.92e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHEMLNNI_01106 5.99e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HHEMLNNI_01107 4.15e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHEMLNNI_01108 9.44e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HHEMLNNI_01109 8.08e-154 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHEMLNNI_01110 4.17e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHEMLNNI_01111 9.26e-98 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HHEMLNNI_01112 7.06e-36 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HHEMLNNI_01113 1.59e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHEMLNNI_01114 8.96e-79 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHEMLNNI_01115 6.37e-125 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHEMLNNI_01116 2.66e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHEMLNNI_01117 2.21e-121 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHEMLNNI_01118 7.7e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHEMLNNI_01119 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHEMLNNI_01120 2.17e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHEMLNNI_01121 5.12e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HHEMLNNI_01122 3.79e-101 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHEMLNNI_01123 1.76e-154 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHEMLNNI_01124 8.5e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHEMLNNI_01125 2.63e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHEMLNNI_01126 3.58e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHEMLNNI_01127 9.74e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHEMLNNI_01128 5.45e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HHEMLNNI_01129 9.49e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHEMLNNI_01130 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HHEMLNNI_01131 7.02e-288 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHEMLNNI_01132 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHEMLNNI_01133 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHEMLNNI_01134 4.33e-95 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHEMLNNI_01135 1.84e-47 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HHEMLNNI_01136 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHEMLNNI_01137 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHEMLNNI_01138 1.77e-158 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HHEMLNNI_01139 1.27e-69 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHEMLNNI_01140 8.48e-106 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHEMLNNI_01141 4.64e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHEMLNNI_01142 1.19e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHEMLNNI_01143 1.83e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HHEMLNNI_01144 2.37e-34 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHEMLNNI_01145 4.15e-153 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HHEMLNNI_01146 8.14e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HHEMLNNI_01147 2.3e-185 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHEMLNNI_01148 1.04e-91 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHEMLNNI_01149 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HHEMLNNI_01150 9.81e-157 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HHEMLNNI_01151 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHEMLNNI_01152 1.09e-109 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HHEMLNNI_01153 1.67e-152 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HHEMLNNI_01154 1.18e-253 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HHEMLNNI_01155 4.09e-249 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HHEMLNNI_01156 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHEMLNNI_01157 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HHEMLNNI_01158 6.55e-251 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HHEMLNNI_01159 4.37e-124 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HHEMLNNI_01160 4.79e-95 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HHEMLNNI_01161 3.37e-27 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HHEMLNNI_01162 6.78e-42 - - - S - - - Protein of unknown function (DUF2508)
HHEMLNNI_01163 9.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHEMLNNI_01164 4.53e-51 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHEMLNNI_01165 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHEMLNNI_01166 1.1e-152 - - - K ko:K03088 - ko00000,ko03021 Sigma-70, region 4
HHEMLNNI_01167 1.8e-136 clpP1 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHEMLNNI_01168 5.14e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHEMLNNI_01170 0.0 gsiB_3 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HHEMLNNI_01171 3.86e-205 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_01172 3.19e-214 - - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_01173 5.54e-246 - - - P ko:K02031,ko:K16202 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_01174 4.05e-244 - - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_01175 3.01e-165 - 3.6.3.21 - E ko:K02028,ko:K10038 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HHEMLNNI_01176 1.23e-141 glnP - - E ko:K02029,ko:K10037,ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Polar amino acid ABC transporter, inner membrane subunit
HHEMLNNI_01177 8.69e-187 glnH - - ET ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Ligated ion channel L-glutamate- and glycine-binding site
HHEMLNNI_01178 2.99e-82 - - - S ko:K08981 - ko00000 Bacterial PH domain
HHEMLNNI_01179 0.0 gabD_2 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHEMLNNI_01180 1.67e-250 - 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HHEMLNNI_01181 9.24e-289 - - - E ko:K01436 - ko00000,ko01000,ko01002 Peptidase dimerisation domain
HHEMLNNI_01182 8.27e-293 - 2.5.1.48, 4.4.1.11 - E ko:K01739,ko:K01761 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HHEMLNNI_01183 2.59e-299 - 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HHEMLNNI_01185 0.0 nhaC_2 - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HHEMLNNI_01186 3.54e-06 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HHEMLNNI_01187 3.41e-299 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HHEMLNNI_01188 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HHEMLNNI_01189 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HHEMLNNI_01190 7.31e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHEMLNNI_01191 3.3e-282 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHEMLNNI_01192 8.37e-307 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HHEMLNNI_01193 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HHEMLNNI_01194 1.88e-194 yaaC - - S - - - YaaC-like Protein
HHEMLNNI_01195 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HHEMLNNI_01196 3.19e-207 - - - K - - - LysR substrate binding domain
HHEMLNNI_01197 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HHEMLNNI_01198 7.82e-265 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HHEMLNNI_01199 4.73e-88 - - - K - - - Helix-turn-helix XRE-family like proteins
HHEMLNNI_01200 2.06e-125 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HHEMLNNI_01201 4.05e-195 malG - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_01202 2.72e-222 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_01203 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_01204 0.0 - - - S ko:K09955 - ko00000 Beta-L-arabinofuranosidase, GH127
HHEMLNNI_01205 5.19e-220 yisR1 3.2.1.23 - K ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 AraC-like ligand binding domain
HHEMLNNI_01206 9.35e-161 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_01207 3.24e-170 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HHEMLNNI_01208 5e-175 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HHEMLNNI_01209 4.88e-161 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HHEMLNNI_01210 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HHEMLNNI_01211 2.81e-96 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHEMLNNI_01212 1.05e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
HHEMLNNI_01213 2.77e-134 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HHEMLNNI_01214 0.0 - - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHEMLNNI_01215 7.25e-123 ykkA - - S - - - Protein of unknown function (DUF664)
HHEMLNNI_01216 7.45e-101 yuxK - - S - - - protein conserved in bacteria
HHEMLNNI_01217 2.63e-55 - - - - - - - -
HHEMLNNI_01218 9.64e-48 - - - S - - - Protein of unknown function, DUF600
HHEMLNNI_01219 1.42e-20 - - - S - - - Protein of unknown function, DUF600
HHEMLNNI_01220 5.61e-107 - - - S - - - SMI1-KNR4 cell-wall
HHEMLNNI_01221 6.65e-104 - - - - - - - -
HHEMLNNI_01222 7.88e-88 - - - S - - - Protein of unknown function, DUF600
HHEMLNNI_01223 7.86e-90 - - - S - - - DNA/RNA non-specific endonuclease
HHEMLNNI_01224 6.87e-99 - - - - - - - -
HHEMLNNI_01225 4.63e-49 - - - U - - - domain, Protein
HHEMLNNI_01226 1.64e-73 - - - - - - - -
HHEMLNNI_01227 2.64e-86 - - - - - - - -
HHEMLNNI_01228 8.83e-64 - - - - - - - -
HHEMLNNI_01229 1.18e-103 - - - S - - - SMI1-KNR4 cell-wall
HHEMLNNI_01230 3.31e-76 - - - - - - - -
HHEMLNNI_01232 3.51e-97 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_01233 7.18e-79 - - - - - - - -
HHEMLNNI_01234 4.06e-236 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_01247 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHEMLNNI_01249 3.83e-19 - - - - - - - -
HHEMLNNI_01250 2.93e-107 yneK - - S - - - Protein of unknown function (DUF2621)
HHEMLNNI_01251 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HHEMLNNI_01252 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HHEMLNNI_01253 8.21e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HHEMLNNI_01254 4.64e-96 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HHEMLNNI_01255 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHEMLNNI_01256 2.51e-46 ynzC - - S - - - UPF0291 protein
HHEMLNNI_01257 2.4e-152 yneB - - L - - - resolvase
HHEMLNNI_01259 8.11e-145 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHEMLNNI_01260 4.36e-283 yuxJ - - EGP - - - Major facilitator superfamily
HHEMLNNI_01262 2.2e-273 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHEMLNNI_01263 8.39e-125 - - - FG - - - Domain of unknown function (DUF4269)
HHEMLNNI_01264 3.84e-115 - - - - - - - -
HHEMLNNI_01265 5.03e-177 - - - K - - - helix_turn_helix isocitrate lyase regulation
HHEMLNNI_01266 1.06e-181 - - - Q - - - Domain of unknown function (DUF2437)
HHEMLNNI_01267 0.0 glcB 2.3.3.9 - C ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HHEMLNNI_01268 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HHEMLNNI_01269 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HHEMLNNI_01270 5.24e-315 - - - C ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 FAD binding domain
HHEMLNNI_01271 5.69e-100 - - - M - - - Acetyltransferase (GNAT) domain
HHEMLNNI_01272 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HHEMLNNI_01273 1.24e-314 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HHEMLNNI_01274 2.02e-220 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HHEMLNNI_01275 3.91e-245 - - - L - - - Belongs to the 'phage' integrase family
HHEMLNNI_01276 1.24e-47 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HHEMLNNI_01277 5e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHEMLNNI_01278 2.05e-180 - - - J - - - Putative SAM-dependent methyltransferase
HHEMLNNI_01279 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHEMLNNI_01280 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHEMLNNI_01281 1.13e-133 cotE - - S ko:K06328 - ko00000 Spore coat protein
HHEMLNNI_01282 3.16e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HHEMLNNI_01283 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HHEMLNNI_01284 7.83e-200 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HHEMLNNI_01285 7.82e-51 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HHEMLNNI_01286 8.12e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HHEMLNNI_01287 3.81e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HHEMLNNI_01288 7.7e-149 - - - L - - - DNA recombination
HHEMLNNI_01289 2.92e-10 - - - - - - - -
HHEMLNNI_01290 0.0 - - - L - - - AAA domain
HHEMLNNI_01291 1.41e-240 - - - L - - - Calcineurin-like phosphoesterase superfamily domain
HHEMLNNI_01292 1.47e-243 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHEMLNNI_01293 0.0 deaD 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHEMLNNI_01294 7.13e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HHEMLNNI_01295 2.85e-128 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHEMLNNI_01296 1.84e-187 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HHEMLNNI_01297 5.43e-180 ymfK - - S - - - Protein of unknown function (DUF3388)
HHEMLNNI_01298 3.99e-53 ymfJ - - S - - - Protein of unknown function (DUF3243)
HHEMLNNI_01299 2.57e-160 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_01300 0.0 ymfH - - S - - - zinc protease
HHEMLNNI_01301 2.01e-304 albE - - S - - - Peptidase M16
HHEMLNNI_01302 2.49e-167 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_01303 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HHEMLNNI_01304 3.72e-06 - - - S - - - YlzJ-like protein
HHEMLNNI_01305 3.79e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HHEMLNNI_01306 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHEMLNNI_01307 1.26e-210 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHEMLNNI_01308 6.18e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HHEMLNNI_01309 8.86e-245 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHEMLNNI_01310 9.26e-139 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HHEMLNNI_01311 1.15e-205 spoVFA - - E ko:K06410 - ko00000 subunit a
HHEMLNNI_01312 5.31e-49 ymxH - - S - - - YlmC YmxH family
HHEMLNNI_01313 1.81e-290 mlpA - - S - - - Belongs to the peptidase M16 family
HHEMLNNI_01314 1.36e-244 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HHEMLNNI_01315 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HHEMLNNI_01316 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHEMLNNI_01317 1.49e-226 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HHEMLNNI_01318 7.37e-222 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHEMLNNI_01319 5.03e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHEMLNNI_01320 5.12e-56 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HHEMLNNI_01321 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHEMLNNI_01322 2.49e-63 ylxQ - - J - - - ribosomal protein
HHEMLNNI_01323 1.42e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HHEMLNNI_01324 3.99e-257 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HHEMLNNI_01325 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HHEMLNNI_01326 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHEMLNNI_01327 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHEMLNNI_01328 2.81e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HHEMLNNI_01329 5.53e-265 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HHEMLNNI_01330 7.6e-176 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HHEMLNNI_01331 2.61e-188 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHEMLNNI_01332 1.86e-116 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHEMLNNI_01333 1.18e-160 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HHEMLNNI_01334 2.91e-199 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHEMLNNI_01335 5.65e-171 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HHEMLNNI_01337 7.05e-171 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHEMLNNI_01338 7.7e-110 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HHEMLNNI_01339 3.87e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HHEMLNNI_01340 3.12e-222 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HHEMLNNI_01341 4.39e-127 - - - - - - - -
HHEMLNNI_01342 3.28e-232 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HHEMLNNI_01343 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHEMLNNI_01344 1.3e-243 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHEMLNNI_01345 1.93e-171 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HHEMLNNI_01346 9.37e-53 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HHEMLNNI_01347 1.04e-145 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HHEMLNNI_01348 8.58e-140 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HHEMLNNI_01349 2.57e-78 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HHEMLNNI_01350 1.01e-273 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHEMLNNI_01351 1.13e-225 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HHEMLNNI_01352 1.61e-92 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HHEMLNNI_01353 3.08e-38 flbD - - N ko:K02385 - ko00000,ko02035 protein, possibly involved in motility
HHEMLNNI_01354 6.89e-189 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HHEMLNNI_01355 8.95e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HHEMLNNI_01356 0.0 - - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein FliK
HHEMLNNI_01358 2.64e-93 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HHEMLNNI_01359 1.19e-312 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HHEMLNNI_01360 6.63e-110 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HHEMLNNI_01361 1.32e-227 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HHEMLNNI_01362 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HHEMLNNI_01363 8.2e-58 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HHEMLNNI_01364 6.48e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HHEMLNNI_01365 2.47e-88 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HHEMLNNI_01366 2.27e-174 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HHEMLNNI_01367 2.15e-300 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HHEMLNNI_01368 1.05e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HHEMLNNI_01369 7.91e-216 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HHEMLNNI_01370 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HHEMLNNI_01371 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHEMLNNI_01372 2.08e-221 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HHEMLNNI_01373 3.09e-215 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHEMLNNI_01374 1.27e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HHEMLNNI_01375 5.58e-104 ylqH - - S ko:K04061 - ko00000,ko02044 FlhB HrpN YscU SpaS Family
HHEMLNNI_01377 2.38e-178 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHEMLNNI_01378 1.03e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHEMLNNI_01379 7.13e-134 sipS 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HHEMLNNI_01380 1.1e-10 - - - - - - - -
HHEMLNNI_01381 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHEMLNNI_01382 0.0 - 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl tRNA synthetase N terminal dom
HHEMLNNI_01383 1.76e-175 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HHEMLNNI_01384 6.52e-124 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHEMLNNI_01385 2.5e-90 - - - S - - - YlqD protein
HHEMLNNI_01386 1.11e-45 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HHEMLNNI_01387 7.93e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HHEMLNNI_01388 1.45e-313 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHEMLNNI_01389 3.83e-68 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHEMLNNI_01390 3.38e-226 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHEMLNNI_01391 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HHEMLNNI_01392 2.38e-14 yfkK - - S - - - Belongs to the UPF0435 family
HHEMLNNI_01393 1.55e-177 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHEMLNNI_01394 1.35e-42 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHEMLNNI_01395 1.72e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HHEMLNNI_01396 3.76e-218 fabD 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 malonyl CoA-acyl carrier protein transacylase
HHEMLNNI_01397 5.46e-233 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHEMLNNI_01398 1.53e-127 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HHEMLNNI_01399 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHEMLNNI_01400 1.55e-195 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HHEMLNNI_01401 2.23e-157 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HHEMLNNI_01402 1.18e-194 yitS - - S - - - protein conserved in bacteria
HHEMLNNI_01403 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HHEMLNNI_01404 5.19e-78 yloU - - S - - - protein conserved in bacteria
HHEMLNNI_01405 4.09e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HHEMLNNI_01407 2.71e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HHEMLNNI_01408 7.3e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHEMLNNI_01409 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HHEMLNNI_01410 1.7e-168 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HHEMLNNI_01411 1.86e-316 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHEMLNNI_01412 6.01e-217 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHEMLNNI_01413 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHEMLNNI_01414 2.8e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHEMLNNI_01415 5.59e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHEMLNNI_01416 3.88e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HHEMLNNI_01417 1.15e-52 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HHEMLNNI_01418 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HHEMLNNI_01419 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HHEMLNNI_01420 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HHEMLNNI_01422 2.31e-156 - - - Q - - - ubiE/COQ5 methyltransferase family
HHEMLNNI_01423 7.28e-142 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHEMLNNI_01424 2.39e-166 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHEMLNNI_01425 1.79e-214 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHEMLNNI_01426 5.05e-187 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HHEMLNNI_01427 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HHEMLNNI_01428 2.55e-270 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HHEMLNNI_01429 5.87e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHEMLNNI_01430 1.59e-211 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HHEMLNNI_01431 7.11e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HHEMLNNI_01432 1.16e-134 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHEMLNNI_01433 5.41e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HHEMLNNI_01434 8.13e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHEMLNNI_01435 9.51e-148 yteA - - T - - - COG1734 DnaK suppressor protein
HHEMLNNI_01436 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHEMLNNI_01437 2.64e-96 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HHEMLNNI_01438 2.21e-178 ylmH - - S - - - conserved protein, contains S4-like domain
HHEMLNNI_01439 7.03e-58 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HHEMLNNI_01440 8.31e-94 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHEMLNNI_01441 2.88e-153 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHEMLNNI_01442 1.95e-191 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HHEMLNNI_01443 6.23e-62 ylmC - - S - - - sporulation protein
HHEMLNNI_01444 3.67e-181 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHEMLNNI_01445 8.95e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHEMLNNI_01446 1.52e-207 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HHEMLNNI_01447 1.02e-241 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHEMLNNI_01448 1.02e-295 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHEMLNNI_01450 2.11e-172 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHEMLNNI_01451 7.29e-247 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HHEMLNNI_01452 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHEMLNNI_01453 9.92e-218 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHEMLNNI_01454 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHEMLNNI_01455 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHEMLNNI_01456 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HHEMLNNI_01457 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HHEMLNNI_01458 1.86e-70 ftsL - - D - - - cell division protein FtsL
HHEMLNNI_01459 2.28e-222 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHEMLNNI_01460 4.81e-103 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HHEMLNNI_01461 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HHEMLNNI_01463 1.25e-205 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHEMLNNI_01464 2.55e-120 ylbP - - K - - - n-acetyltransferase
HHEMLNNI_01465 1.1e-102 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HHEMLNNI_01466 7.12e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HHEMLNNI_01467 4.91e-121 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HHEMLNNI_01468 1.96e-294 ylbM - - S - - - Belongs to the UPF0348 family
HHEMLNNI_01469 4.78e-249 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HHEMLNNI_01470 1e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HHEMLNNI_01471 6.16e-280 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HHEMLNNI_01472 1.28e-108 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHEMLNNI_01473 2.04e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HHEMLNNI_01474 3.45e-83 - - - S - - - Methylthioribose kinase
HHEMLNNI_01475 4.89e-63 ylbG - - S - - - UPF0298 protein
HHEMLNNI_01476 4.07e-92 ylbF - - S - - - Belongs to the UPF0342 family
HHEMLNNI_01477 3.16e-184 - - - HJ ko:K05844 - ko00000,ko01000,ko03009 Prokaryotic glutathione synthetase, ATP-grasp domain
HHEMLNNI_01478 7.5e-43 ylbE - - S - - - YlbE-like protein
HHEMLNNI_01479 5.03e-95 ylbD - - S - - - Putative coat protein
HHEMLNNI_01480 1.68e-109 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein, possibly involved in aromatic compounds catabolism
HHEMLNNI_01481 6.29e-272 ylbC - - S - - - protein with SCP PR1 domains
HHEMLNNI_01482 1.34e-83 ylbA - - S - - - YugN-like family
HHEMLNNI_01483 9.66e-110 - - - - - - - -
HHEMLNNI_01484 1.13e-120 yozB - - S ko:K08976 - ko00000 membrane
HHEMLNNI_01485 1.46e-68 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HHEMLNNI_01486 8.77e-144 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HHEMLNNI_01487 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHEMLNNI_01488 2.38e-253 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HHEMLNNI_01489 6.42e-205 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HHEMLNNI_01490 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HHEMLNNI_01491 1.92e-56 ylaN - - S - - - Belongs to the UPF0358 family
HHEMLNNI_01492 1.12e-121 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HHEMLNNI_01493 0.0 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HHEMLNNI_01494 1.3e-44 ylaI - - S - - - protein conserved in bacteria
HHEMLNNI_01495 3.25e-70 ylaH - - S - - - YlaH-like protein
HHEMLNNI_01496 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HHEMLNNI_01497 1.13e-17 - - - S - - - Family of unknown function (DUF5325)
HHEMLNNI_01498 9.56e-212 - 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HHEMLNNI_01499 3.73e-198 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HHEMLNNI_01500 2.42e-152 yktB - - S - - - Belongs to the UPF0637 family
HHEMLNNI_01501 6.3e-55 yktA - - S - - - Belongs to the UPF0223 family
HHEMLNNI_01502 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HHEMLNNI_01503 7.16e-297 - - - O - - - Peptidase family M48
HHEMLNNI_01504 7.22e-175 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HHEMLNNI_01505 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HHEMLNNI_01506 6.88e-89 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 cell redox homeostasis
HHEMLNNI_01507 1.7e-207 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_01508 3.37e-223 - - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_01509 0.0 appA_2 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HHEMLNNI_01510 5.5e-238 - - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_01511 3.07e-239 appD - - P ko:K02031,ko:K16202 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_01512 1.09e-95 - - - IQ - - - PFAM short-chain dehydrogenase reductase SDR
HHEMLNNI_01513 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHEMLNNI_01514 6.67e-248 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHEMLNNI_01515 1.5e-228 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHEMLNNI_01516 3.83e-256 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHEMLNNI_01517 3.28e-128 ykyA - - L - - - Putative cell-wall binding lipoprotein
HHEMLNNI_01518 1.8e-33 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HHEMLNNI_01519 2.58e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHEMLNNI_01520 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
HHEMLNNI_01521 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHEMLNNI_01522 6.6e-150 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HHEMLNNI_01523 1.25e-107 ykuV - - CO - - - thiol-disulfide
HHEMLNNI_01524 3.15e-131 ykuU - - O - - - Alkyl hydroperoxide reductase
HHEMLNNI_01525 1.08e-172 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HHEMLNNI_01526 1.46e-50 ykuS - - S - - - Belongs to the UPF0180 family
HHEMLNNI_01527 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHEMLNNI_01528 3.11e-290 - 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HHEMLNNI_01529 2.79e-115 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHEMLNNI_01530 5.28e-188 - - - S ko:K07088 - ko00000 Membrane transport protein
HHEMLNNI_01531 4.39e-244 - - - T - - - Metal dependent phosphohydrolases with conserved 'HD' motif.
HHEMLNNI_01532 5.65e-256 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HHEMLNNI_01534 1.92e-126 copC - - S ko:K07156 - ko00000,ko02000 CopC domain
HHEMLNNI_01535 3.27e-237 ytvI - - S - - - AI-2E family transporter
HHEMLNNI_01536 1.73e-143 yhfK - - GM - - - NmrA-like family
HHEMLNNI_01537 1.64e-290 - - - E - - - Peptidase family M28
HHEMLNNI_01538 1.66e-244 - - - C - - - Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HHEMLNNI_01540 1.62e-128 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HHEMLNNI_01541 9.47e-39 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
HHEMLNNI_01542 1.16e-62 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HHEMLNNI_01543 1.66e-42 - - - - - - - -
HHEMLNNI_01544 1.29e-188 ykrA - - S - - - hydrolases of the HAD superfamily
HHEMLNNI_01546 9.69e-77 - - - - - - - -
HHEMLNNI_01547 2.91e-99 yqiW - - S - - - Belongs to the UPF0403 family
HHEMLNNI_01548 8.99e-293 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHEMLNNI_01549 4e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHEMLNNI_01550 2.17e-241 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHEMLNNI_01551 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHEMLNNI_01552 3.58e-263 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HHEMLNNI_01553 0.0 bkdR - - KT - - - Transcriptional regulator
HHEMLNNI_01554 3.32e-48 yqzF - - S - - - Protein of unknown function (DUF2627)
HHEMLNNI_01555 4.19e-154 - - - M - - - First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHEMLNNI_01556 8.04e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HHEMLNNI_01557 9.21e-305 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HHEMLNNI_01558 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HHEMLNNI_01559 6.48e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HHEMLNNI_01560 2.32e-193 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HHEMLNNI_01561 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHEMLNNI_01562 2.41e-203 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HHEMLNNI_01563 2.03e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHEMLNNI_01564 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHEMLNNI_01565 1.22e-89 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHEMLNNI_01566 5.96e-87 yqhY - - S - - - protein conserved in bacteria
HHEMLNNI_01567 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HHEMLNNI_01568 7.32e-105 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHEMLNNI_01569 3.08e-74 - - - - - - - -
HHEMLNNI_01570 2.98e-117 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HHEMLNNI_01571 4.27e-146 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HHEMLNNI_01572 2.92e-123 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HHEMLNNI_01573 4.33e-262 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HHEMLNNI_01574 6.3e-54 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HHEMLNNI_01575 1.98e-40 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HHEMLNNI_01576 6.16e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HHEMLNNI_01577 1.94e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HHEMLNNI_01578 3.84e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
HHEMLNNI_01579 9.91e-68 - - - S - - - YfzA-like protein
HHEMLNNI_01580 3.54e-128 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HHEMLNNI_01581 7.96e-127 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHEMLNNI_01582 5.61e-251 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HHEMLNNI_01583 4.42e-116 yqhR - - S - - - Conserved membrane protein YqhR
HHEMLNNI_01584 2.46e-79 - - - - - - - -
HHEMLNNI_01585 1.47e-213 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HHEMLNNI_01586 6.58e-101 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HHEMLNNI_01587 5.42e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HHEMLNNI_01588 1.03e-203 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HHEMLNNI_01589 0.0 uvrD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HHEMLNNI_01590 6.16e-197 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HHEMLNNI_01591 4.68e-82 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HHEMLNNI_01592 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HHEMLNNI_01593 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HHEMLNNI_01594 1.46e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HHEMLNNI_01595 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HHEMLNNI_01596 1.4e-196 yqhG - - S - - - Bacterial protein YqhG of unknown function
HHEMLNNI_01598 1.85e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HHEMLNNI_01599 2.65e-48 B4168_0554 - - S - - - Protein of unknown function (DUF2626)
HHEMLNNI_01602 4.4e-106 - - - - - - - -
HHEMLNNI_01604 1.65e-97 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HHEMLNNI_01605 1.22e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HHEMLNNI_01606 3.58e-55 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HHEMLNNI_01616 2.73e-241 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HHEMLNNI_01617 2.24e-238 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHEMLNNI_01618 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HHEMLNNI_01619 4.39e-97 - - - - - - - -
HHEMLNNI_01620 4.62e-111 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HHEMLNNI_01621 6.94e-07 - - - - - - - -
HHEMLNNI_01623 1.77e-176 - - - - - - - -
HHEMLNNI_01624 1.49e-163 - - - - - - - -
HHEMLNNI_01625 1.91e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
HHEMLNNI_01626 2.16e-79 - - - S - - - Protein of unknown function (DUF1360)
HHEMLNNI_01627 1.74e-178 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HHEMLNNI_01628 2.66e-219 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HHEMLNNI_01629 5.27e-193 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHEMLNNI_01630 1.02e-142 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HHEMLNNI_01631 3.74e-82 yjbL - - S - - - Belongs to the UPF0738 family
HHEMLNNI_01632 6.53e-127 yjbK - - S - - - protein conserved in bacteria
HHEMLNNI_01633 4.71e-142 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HHEMLNNI_01634 1.67e-95 yjbI - - S ko:K06886 - ko00000 COG2346 Truncated hemoglobins
HHEMLNNI_01635 7.36e-221 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HHEMLNNI_01637 2.06e-302 coiA - - S ko:K06198 - ko00000 Competence protein
HHEMLNNI_01638 5.5e-148 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HHEMLNNI_01639 2.03e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHEMLNNI_01641 2.05e-127 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHEMLNNI_01642 1.58e-301 - - - S - - - Putative glycosyl hydrolase domain
HHEMLNNI_01643 1.83e-12 yoeD - - G - - - Helix-turn-helix domain
HHEMLNNI_01644 1.5e-144 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HHEMLNNI_01645 3.04e-128 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HHEMLNNI_01646 1.48e-135 - - - CO - - - Redoxin
HHEMLNNI_01648 6.64e-234 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HHEMLNNI_01649 1.94e-15 - - - - - - - -
HHEMLNNI_01650 2.82e-183 yjbA - - S - - - Belongs to the UPF0736 family
HHEMLNNI_01651 3.59e-202 yjaZ - - O - - - Zn-dependent protease
HHEMLNNI_01652 1.49e-176 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HHEMLNNI_01653 1.82e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HHEMLNNI_01654 2.77e-172 ykwD - - J - - - protein with SCP PR1 domains
HHEMLNNI_01655 1.16e-134 - 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HHEMLNNI_01657 0.0 - 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Poly A polymerase head domain
HHEMLNNI_01658 0.0 - - - - - - - -
HHEMLNNI_01659 2.59e-187 - - - G - - - Belongs to the carbohydrate kinase PfkB family
HHEMLNNI_01660 3.86e-284 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HHEMLNNI_01661 6.8e-227 - - - O - - - ADP-ribosylglycohydrolase
HHEMLNNI_01662 4.36e-149 - - - K - - - UTRA domain
HHEMLNNI_01663 1.28e-294 fabF 2.3.1.179 - I ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHEMLNNI_01664 1.53e-214 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHEMLNNI_01666 7.3e-19 comZ - - S ko:K02254 - ko00000,ko02044 Competence protein ComG
HHEMLNNI_01667 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHEMLNNI_01668 3.32e-202 - 5.1.3.2 - GM ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HHEMLNNI_01669 6.55e-155 yjaU - - I - - - carboxylic ester hydrolase activity
HHEMLNNI_01670 8.91e-220 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHEMLNNI_01671 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HHEMLNNI_01672 2.17e-266 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HHEMLNNI_01673 1.01e-274 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HHEMLNNI_01674 8.28e-176 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HHEMLNNI_01675 1.87e-289 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HHEMLNNI_01676 3.4e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHEMLNNI_01677 1.17e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HHEMLNNI_01678 1.57e-195 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HHEMLNNI_01679 2.72e-102 - - - K - - - Acetyltransferase (GNAT) domain
HHEMLNNI_01680 1.78e-140 - - - - - - - -
HHEMLNNI_01681 5.88e-296 ywqB - - S - - - zinc ion binding
HHEMLNNI_01682 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HHEMLNNI_01684 6.44e-18 - - - S - - - Intracellular proteinase inhibitor
HHEMLNNI_01685 7.65e-188 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HHEMLNNI_01686 9.1e-191 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HHEMLNNI_01687 1.01e-56 - - - - - - - -
HHEMLNNI_01688 2.36e-84 ytwF - - P - - - Sulfurtransferase
HHEMLNNI_01689 2.04e-118 - - - - - - - -
HHEMLNNI_01690 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HHEMLNNI_01691 6.94e-200 ykgA - - E - - - Amidinotransferase
HHEMLNNI_01692 1.53e-62 - - - S - - - IDEAL
HHEMLNNI_01693 0.0 asnH 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HHEMLNNI_01694 1.74e-96 cheW - - NT ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 chemotaxis
HHEMLNNI_01695 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HHEMLNNI_01696 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HHEMLNNI_01697 0.0 addB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 exonuclease activity
HHEMLNNI_01698 4.58e-82 - - - - - - - -
HHEMLNNI_01699 6.09e-144 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HHEMLNNI_01700 1.5e-184 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHEMLNNI_01701 3.69e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHEMLNNI_01702 2.52e-205 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HHEMLNNI_01703 4.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HHEMLNNI_01704 1.04e-214 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HHEMLNNI_01705 6.86e-108 - - - S - - - DinB family
HHEMLNNI_01706 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HHEMLNNI_01707 1.45e-171 - - - S ko:K07010 - ko00000,ko01002 Peptidase C26
HHEMLNNI_01708 1.01e-273 - 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HHEMLNNI_01709 2.51e-151 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil DNA glycosylase superfamily
HHEMLNNI_01711 5.63e-275 - - - Q - - - COG1228 Imidazolonepropionase and related amidohydrolases
HHEMLNNI_01712 2.47e-58 abrB - - K ko:K06284 - ko00000,ko03000 SpoVT / AbrB like domain
HHEMLNNI_01713 1.58e-59 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HHEMLNNI_01714 7.63e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HHEMLNNI_01715 5.22e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HHEMLNNI_01716 0.0 cafA - - J ko:K08301 - ko00000,ko01000,ko03009,ko03019 ribonuclease, Rne Rng family
HHEMLNNI_01717 7.19e-198 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HHEMLNNI_01718 2.61e-167 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HHEMLNNI_01719 2.02e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HHEMLNNI_01720 4.06e-121 - - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HHEMLNNI_01721 8.85e-97 - 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaC family
HHEMLNNI_01722 4.46e-119 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HHEMLNNI_01723 6.84e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HHEMLNNI_01724 3.82e-157 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HHEMLNNI_01725 1.22e-102 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HHEMLNNI_01726 1.02e-203 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HHEMLNNI_01727 4.89e-239 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HHEMLNNI_01728 2.48e-157 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HHEMLNNI_01729 1.27e-135 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HHEMLNNI_01730 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HHEMLNNI_01731 2.89e-252 - - - - ko:K06380 - ko00000 -
HHEMLNNI_01732 2.26e-155 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HHEMLNNI_01733 1.09e-309 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HHEMLNNI_01734 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHEMLNNI_01735 2.36e-42 - - - - - - - -
HHEMLNNI_01736 5.5e-149 - - - - - - - -
HHEMLNNI_01737 3.09e-245 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HHEMLNNI_01738 5.55e-211 - - - - - - - -
HHEMLNNI_01739 1.62e-240 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HHEMLNNI_01740 2.13e-313 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HHEMLNNI_01741 4e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HHEMLNNI_01742 1.44e-178 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HHEMLNNI_01743 2.17e-214 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HHEMLNNI_01744 2.21e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HHEMLNNI_01745 0.0 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HHEMLNNI_01746 2.65e-140 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HHEMLNNI_01747 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HHEMLNNI_01748 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HHEMLNNI_01749 2.85e-303 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHEMLNNI_01750 3.98e-295 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHEMLNNI_01751 1.09e-230 ysoA - - O - - - COG0457 FOG TPR repeat
HHEMLNNI_01752 2.02e-144 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHEMLNNI_01753 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHEMLNNI_01754 3.13e-252 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HHEMLNNI_01755 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HHEMLNNI_01756 2.5e-235 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HHEMLNNI_01757 3.04e-111 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HHEMLNNI_01758 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HHEMLNNI_01759 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HHEMLNNI_01760 8.81e-98 - - - - - - - -
HHEMLNNI_01761 0.0 - - - M - - - Glycosyl transferase family group 2
HHEMLNNI_01762 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HHEMLNNI_01765 4.56e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HHEMLNNI_01766 5.76e-140 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHEMLNNI_01767 5.64e-175 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HHEMLNNI_01768 4.75e-249 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HHEMLNNI_01769 3.77e-250 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HHEMLNNI_01770 3.13e-42 - - - C - - - 4Fe-4S binding domain
HHEMLNNI_01771 5.24e-193 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HHEMLNNI_01772 4e-105 ysmB - - K - - - transcriptional
HHEMLNNI_01773 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHEMLNNI_01774 2.33e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HHEMLNNI_01775 2.77e-45 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_01776 9.16e-105 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HHEMLNNI_01777 4.17e-186 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HHEMLNNI_01778 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HHEMLNNI_01779 5.12e-145 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HHEMLNNI_01780 6.08e-294 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HHEMLNNI_01781 7.17e-99 yslB - - S - - - Protein of unknown function (DUF2507)
HHEMLNNI_01782 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHEMLNNI_01783 1.37e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HHEMLNNI_01784 6.53e-223 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HHEMLNNI_01785 4.25e-173 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HHEMLNNI_01786 1.38e-178 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HHEMLNNI_01787 6.25e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_01788 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHEMLNNI_01789 7.25e-88 yshE - - S ko:K08989 - ko00000 membrane
HHEMLNNI_01790 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHEMLNNI_01791 7.57e-315 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HHEMLNNI_01792 2.19e-80 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HHEMLNNI_01793 5.01e-118 yshB - - S - - - membrane protein, required for colicin V production
HHEMLNNI_01794 6.35e-46 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HHEMLNNI_01795 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHEMLNNI_01796 8.23e-247 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHEMLNNI_01797 5.88e-175 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHEMLNNI_01798 3.13e-42 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HHEMLNNI_01800 1.02e-22 - - - - - - - -
HHEMLNNI_01801 5.26e-260 ysdC - - G - - - COG1363 Cellulase M and related proteins
HHEMLNNI_01802 7.91e-86 ysdB - - S - - - Sigma-w pathway protein YsdB
HHEMLNNI_01803 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHEMLNNI_01804 9.32e-70 ywcB - - S - - - Protein of unknown function, DUF485
HHEMLNNI_01805 5.42e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHEMLNNI_01806 7.54e-40 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HHEMLNNI_01807 4.04e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHEMLNNI_01808 1.48e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HHEMLNNI_01809 2.79e-153 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_01810 4.41e-304 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHEMLNNI_01811 8.9e-168 - - - - - - - -
HHEMLNNI_01812 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HHEMLNNI_01813 2.3e-228 - - - C - - - Aldo/keto reductase family
HHEMLNNI_01814 4.04e-241 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HHEMLNNI_01815 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHEMLNNI_01816 1.16e-208 ytxC - - S - - - YtxC-like family
HHEMLNNI_01817 2.85e-287 mqnC 1.21.98.1 - H ko:K11784 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
HHEMLNNI_01818 1.48e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HHEMLNNI_01819 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HHEMLNNI_01820 1.52e-103 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHEMLNNI_01821 2.76e-86 - - - - - - - -
HHEMLNNI_01822 2.59e-89 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HHEMLNNI_01823 6.04e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHEMLNNI_01824 2.44e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHEMLNNI_01825 7.43e-136 ytaF - - P - - - Probably functions as a manganese efflux pump
HHEMLNNI_01826 7.85e-204 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHEMLNNI_01827 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHEMLNNI_01828 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HHEMLNNI_01829 1.14e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_01830 1.58e-86 - - - K ko:K03719 - ko00000,ko03000,ko03036 helix_turn_helix ASNC type
HHEMLNNI_01831 7.32e-219 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HHEMLNNI_01832 1.08e-306 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HHEMLNNI_01833 1.53e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HHEMLNNI_01834 4.98e-96 - - - S - - - UPF0756 membrane protein
HHEMLNNI_01835 9.31e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HHEMLNNI_01836 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HHEMLNNI_01837 1.14e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHEMLNNI_01838 1.68e-229 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HHEMLNNI_01839 7.77e-197 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHEMLNNI_01840 2.9e-149 lutR_1 - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HHEMLNNI_01841 1.04e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HHEMLNNI_01842 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HHEMLNNI_01843 4.62e-70 ytrH - - S - - - Sporulation protein YtrH
HHEMLNNI_01844 1.03e-117 ytrI - - - - - - -
HHEMLNNI_01845 2.99e-220 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HHEMLNNI_01846 3.35e-11 ytpI - - S - - - YtpI-like protein
HHEMLNNI_01847 2.37e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HHEMLNNI_01849 1.45e-166 ytkL - - S - - - Belongs to the UPF0173 family
HHEMLNNI_01850 5.11e-265 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HHEMLNNI_01851 1.35e-85 - - - - - - - -
HHEMLNNI_01852 8.7e-179 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_01854 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HHEMLNNI_01855 1.01e-295 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HHEMLNNI_01857 5.8e-219 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
HHEMLNNI_01858 4.13e-275 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHEMLNNI_01859 1.19e-231 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HHEMLNNI_01860 2.76e-110 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHEMLNNI_01861 8.63e-258 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HHEMLNNI_01862 1.19e-97 ytfJ - - S - - - Sporulation protein YtfJ
HHEMLNNI_01863 5.89e-161 ytfI - - S - - - Protein of unknown function (DUF2953)
HHEMLNNI_01864 1.14e-129 yteJ - - S - - - RDD family
HHEMLNNI_01865 2.4e-231 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HHEMLNNI_01866 1.17e-38 - - - S ko:K06418,ko:K06419 - ko00000 spore protein
HHEMLNNI_01867 2.26e-286 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHEMLNNI_01868 4.06e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HHEMLNNI_01869 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHEMLNNI_01870 2.57e-190 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HHEMLNNI_01871 3.71e-147 yttP - - K - - - Transcriptional regulator
HHEMLNNI_01872 2.37e-37 - - - L ko:K07496 - ko00000 Transposase
HHEMLNNI_01873 3.65e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HHEMLNNI_01874 9.94e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHEMLNNI_01875 2.24e-300 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHEMLNNI_01876 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 COG0744 Membrane carboxypeptidase (penicillin-binding protein)
HHEMLNNI_01877 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HHEMLNNI_01878 1.41e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HHEMLNNI_01879 1.02e-147 acuB - - S ko:K04767 - ko00000 Acetoin utilization protein AcuB
HHEMLNNI_01880 5.67e-303 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HHEMLNNI_01881 1.24e-237 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HHEMLNNI_01882 4.11e-252 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HHEMLNNI_01883 3.48e-29 ytxH - - S - - - COG4980 Gas vesicle protein
HHEMLNNI_01884 1.68e-84 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHEMLNNI_01885 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HHEMLNNI_01886 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HHEMLNNI_01887 9.49e-136 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHEMLNNI_01888 2.92e-189 ytpQ - - S - - - Belongs to the UPF0354 family
HHEMLNNI_01889 1.98e-74 ytpP - - CO - - - Thioredoxin
HHEMLNNI_01890 2.47e-189 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HHEMLNNI_01891 5.77e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HHEMLNNI_01892 1.86e-116 yjjX - - F - - - Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HHEMLNNI_01893 3.18e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HHEMLNNI_01894 2.23e-65 ytzB - - - - - - -
HHEMLNNI_01895 5.3e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHEMLNNI_01897 1.35e-198 ytmP - - M - - - Phosphotransferase
HHEMLNNI_01898 4.39e-211 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HHEMLNNI_01899 8.62e-166 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_01900 4.58e-69 - - - S - - - PFAM Uncharacterised protein family UPF0150
HHEMLNNI_01901 7.49e-281 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHEMLNNI_01902 6.28e-248 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHEMLNNI_01903 3.27e-227 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHEMLNNI_01904 3.32e-278 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HHEMLNNI_01905 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HHEMLNNI_01906 1.07e-146 cidB - - M - - - effector of murein hydrolase
HHEMLNNI_01907 1.41e-84 - - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HHEMLNNI_01908 2.21e-138 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HHEMLNNI_01909 1.32e-219 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HHEMLNNI_01910 5.55e-212 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HHEMLNNI_01911 2.52e-63 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HHEMLNNI_01912 4.68e-195 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HHEMLNNI_01913 8.58e-103 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HHEMLNNI_01914 4.69e-43 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HHEMLNNI_01915 6.1e-171 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HHEMLNNI_01916 1.8e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HHEMLNNI_01917 3.03e-258 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HHEMLNNI_01918 0.0 ytgP - - S ko:K03328,ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHEMLNNI_01919 7.05e-216 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HHEMLNNI_01920 3.75e-94 yugU - - S - - - Uncharacterised protein family UPF0047
HHEMLNNI_01921 1.12e-291 yhaA1 - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HHEMLNNI_01922 1.24e-264 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HHEMLNNI_01923 5.5e-58 - - - - - - - -
HHEMLNNI_01924 1.35e-21 - - - - - - - -
HHEMLNNI_01925 1.12e-99 - - - S - - - An automated process has identified a potential problem with this gene model
HHEMLNNI_01926 2.33e-169 - - - S - - - Protein of unknown function (DUF3100)
HHEMLNNI_01927 2.28e-309 - - - S ko:K12941 - ko00000,ko01002 amidohydrolase
HHEMLNNI_01928 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HHEMLNNI_01929 1.15e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HHEMLNNI_01930 1.67e-245 yttB - - EGP - - - Major facilitator superfamily
HHEMLNNI_01932 7.9e-136 ytqB - - J - - - Putative rRNA methylase
HHEMLNNI_01933 8.11e-138 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HHEMLNNI_01934 4.53e-195 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HHEMLNNI_01935 4.81e-98 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HHEMLNNI_01936 1.42e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHEMLNNI_01937 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HHEMLNNI_01938 9.52e-197 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HHEMLNNI_01939 7.17e-233 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HHEMLNNI_01940 6.58e-175 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HHEMLNNI_01941 5.58e-178 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHEMLNNI_01942 5.41e-115 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HHEMLNNI_01943 1.36e-285 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HHEMLNNI_01944 5.16e-110 ywpF - - S - - - YwpF-like protein
HHEMLNNI_01946 4.5e-283 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HHEMLNNI_01947 6.97e-150 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HHEMLNNI_01948 1.52e-154 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HHEMLNNI_01949 1.92e-140 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
HHEMLNNI_01950 8.54e-222 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HHEMLNNI_01951 5.06e-194 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_01952 9.44e-200 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_01953 1.23e-207 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_01954 4.14e-138 pgpB3 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HHEMLNNI_01955 4.55e-303 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHEMLNNI_01956 4.63e-101 - - - S - - - Putative small multi-drug export protein
HHEMLNNI_01957 1.2e-105 - - - S - - - DinB superfamily
HHEMLNNI_01958 9.46e-77 - - - S - - - Protein of unknown function (DUF1516)
HHEMLNNI_01959 4.94e-109 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HHEMLNNI_01960 9.87e-211 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HHEMLNNI_01961 4.19e-212 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HHEMLNNI_01964 2.25e-29 - - - - - - - -
HHEMLNNI_01965 4.19e-92 yugN - - S - - - YugN-like family
HHEMLNNI_01966 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HHEMLNNI_01967 1.58e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HHEMLNNI_01968 2.44e-288 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HHEMLNNI_01969 2.41e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HHEMLNNI_01970 2.25e-76 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HHEMLNNI_01971 1.99e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HHEMLNNI_01972 6.3e-177 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HHEMLNNI_01973 9.49e-283 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HHEMLNNI_01974 7.3e-111 alaR - - K - - - Transcriptional regulator
HHEMLNNI_01975 4.49e-112 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHEMLNNI_01976 6.56e-187 - - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HHEMLNNI_01977 1.81e-55 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHEMLNNI_01978 1.56e-296 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HHEMLNNI_01979 5.93e-60 - - - - - - - -
HHEMLNNI_01980 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HHEMLNNI_01981 2.38e-103 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HHEMLNNI_01982 1.2e-145 yuiC - - S - - - protein conserved in bacteria
HHEMLNNI_01983 2.23e-62 yuiB - - S - - - Putative membrane protein
HHEMLNNI_01984 1.09e-293 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HHEMLNNI_01985 3.18e-237 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HHEMLNNI_01986 1.93e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HHEMLNNI_01987 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HHEMLNNI_01988 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HHEMLNNI_01989 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HHEMLNNI_01990 3.3e-198 - - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HHEMLNNI_01991 4.06e-140 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HHEMLNNI_01992 2.5e-79 yutM - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HHEMLNNI_01993 3.32e-13 - - - S - - - Spo0E like sporulation regulatory protein
HHEMLNNI_01994 5.12e-267 mqnE 2.5.1.120 - H ko:K18285 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HHEMLNNI_01995 1.42e-209 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHEMLNNI_01996 9.92e-57 - - - - - - - -
HHEMLNNI_01997 3.63e-54 yuzB - - S - - - Belongs to the UPF0349 family
HHEMLNNI_01998 0.0 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HHEMLNNI_01999 6.51e-69 yuzD - - S - - - protein conserved in bacteria
HHEMLNNI_02000 4.25e-49 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HHEMLNNI_02001 1.3e-208 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHEMLNNI_02002 2.38e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HHEMLNNI_02003 1.2e-303 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HHEMLNNI_02004 5.3e-269 yutH - - S - - - Spore coat protein
HHEMLNNI_02005 1.37e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HHEMLNNI_02006 8.01e-175 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHEMLNNI_02007 4.73e-102 yutE - - S - - - Protein of unknown function DUF86
HHEMLNNI_02008 1.79e-59 - - - - - - - -
HHEMLNNI_02009 6.09e-67 yutD - - S - - - protein conserved in bacteria
HHEMLNNI_02010 1.18e-121 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHEMLNNI_02011 3.12e-222 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HHEMLNNI_02012 6.5e-261 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HHEMLNNI_02013 0.0 - - - C ko:K18218 - ko00000,ko00002,ko01504,ko02000 Na+/H+ antiporter family
HHEMLNNI_02014 8.91e-223 - - - L ko:K07496 - ko00000 Transposase
HHEMLNNI_02015 3.14e-179 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HHEMLNNI_02016 5.39e-116 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHEMLNNI_02017 8.49e-202 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHEMLNNI_02018 4.8e-66 yunC - - S - - - Domain of unknown function (DUF1805)
HHEMLNNI_02019 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HHEMLNNI_02020 8.56e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HHEMLNNI_02021 6.03e-216 yunF - - S - - - Protein of unknown function DUF72
HHEMLNNI_02022 1.7e-84 - - - S - - - Domain of unknown function (DUF5082)
HHEMLNNI_02023 1.26e-67 - - - - - - - -
HHEMLNNI_02024 7.58e-190 - - - - - - - -
HHEMLNNI_02026 4.69e-50 - - - - - - - -
HHEMLNNI_02027 3.3e-50 - - - - - - - -
HHEMLNNI_02028 3.35e-199 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_02029 1.85e-58 - - - S - - - Family of unknown function (DUF5344)
HHEMLNNI_02030 7.31e-213 - - - S - - - Phosphotransferase enzyme family
HHEMLNNI_02031 7.74e-232 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HHEMLNNI_02032 1.54e-183 msmR - - K - - - AraC family transcriptional regulator
HHEMLNNI_02033 3.07e-239 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
HHEMLNNI_02034 4.12e-152 - - - Q - - - Methyltransferase domain
HHEMLNNI_02035 1.66e-11 - - - Q - - - Methyltransferase domain
HHEMLNNI_02036 1.93e-54 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
HHEMLNNI_02037 6.62e-69 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HHEMLNNI_02038 2.61e-24 - - - S - - - YhfH-like protein
HHEMLNNI_02039 2.09e-305 aceA 4.1.3.1 - C ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Isocitrate lyase
HHEMLNNI_02040 9.76e-64 - - - - - - - -
HHEMLNNI_02041 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HHEMLNNI_02042 2.18e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HHEMLNNI_02043 1.83e-300 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHEMLNNI_02044 5.41e-310 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HHEMLNNI_02045 6.61e-185 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HHEMLNNI_02046 7.34e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHEMLNNI_02047 3.91e-215 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HHEMLNNI_02048 4.64e-124 - - - S - - - Cobalamin adenosyltransferase
HHEMLNNI_02049 4.86e-198 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HHEMLNNI_02050 8.98e-149 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HHEMLNNI_02051 1.99e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHEMLNNI_02052 6.74e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HHEMLNNI_02053 1.43e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HHEMLNNI_02054 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HHEMLNNI_02055 5.03e-273 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HHEMLNNI_02056 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HHEMLNNI_02057 2.87e-288 - - - EGP - - - Major Facilitator Superfamily
HHEMLNNI_02058 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
HHEMLNNI_02059 6.17e-165 - - - S - - - Glycosyltransferase like family
HHEMLNNI_02060 2.33e-195 - 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HHEMLNNI_02061 6.97e-09 - - - - - - - -
HHEMLNNI_02062 1.16e-142 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HHEMLNNI_02063 1.66e-315 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHEMLNNI_02064 5.66e-312 - - - S - - - protein conserved in bacteria
HHEMLNNI_02065 5.03e-75 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHEMLNNI_02066 5.57e-135 - - - - - - - -
HHEMLNNI_02067 3.26e-174 - - - - - - - -
HHEMLNNI_02069 1.12e-104 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HHEMLNNI_02070 2.11e-80 - - - S ko:K15977 - ko00000 DoxX
HHEMLNNI_02071 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHEMLNNI_02072 8.7e-178 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HHEMLNNI_02073 1.87e-176 - 3.1.1.1 - S ko:K03928 - ko00000,ko01000 COG1647 Esterase lipase
HHEMLNNI_02074 7.78e-235 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHEMLNNI_02075 9.6e-38 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HHEMLNNI_02076 8.16e-103 yclD - - - - - - -
HHEMLNNI_02077 0.0 - - - S ko:K07793 ko02020,map02020 ko00000,ko00001,ko02000 Tripartite tricarboxylate transporter TctA family
HHEMLNNI_02078 1.09e-99 - - - S - - - Tripartite tricarboxylate transporter TctB family
HHEMLNNI_02079 1.36e-219 - - - S - - - Tripartite tricarboxylate transporter family receptor
HHEMLNNI_02080 9.15e-285 - 4.2.1.158 - M ko:K20022 - ko00000,ko01000 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
HHEMLNNI_02081 0.0 - - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHEMLNNI_02082 3.37e-220 - 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
HHEMLNNI_02083 1.93e-151 - - - K - - - FCD
HHEMLNNI_02084 9.59e-305 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHEMLNNI_02085 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HHEMLNNI_02086 7.44e-164 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHEMLNNI_02087 9.79e-278 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HHEMLNNI_02088 1.46e-240 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHEMLNNI_02089 1.49e-230 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HHEMLNNI_02090 6.69e-263 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HHEMLNNI_02092 5.2e-54 XAC3035 - - O ko:K06191 - ko00000 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HHEMLNNI_02093 5.42e-310 sigL - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HHEMLNNI_02094 4.06e-134 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHEMLNNI_02095 1.09e-290 - - - E - - - Peptidase dimerisation domain
HHEMLNNI_02096 7.15e-75 - - - S ko:K09940 - ko00000 Domain of unknown function (DUF4870)
HHEMLNNI_02097 1.67e-272 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HHEMLNNI_02098 5.2e-139 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HHEMLNNI_02099 1.8e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HHEMLNNI_02100 1.6e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HHEMLNNI_02101 4.07e-52 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HHEMLNNI_02102 2.16e-228 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HHEMLNNI_02103 1.09e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HHEMLNNI_02104 4.57e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HHEMLNNI_02105 1.28e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Nudix hydrolase
HHEMLNNI_02106 2.04e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHEMLNNI_02107 3.95e-252 yvcD - - S - - - COG0457 FOG TPR repeat
HHEMLNNI_02108 5.17e-312 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HHEMLNNI_02109 1.58e-186 - - - K - - - FR47-like protein
HHEMLNNI_02110 8.46e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HHEMLNNI_02111 6.86e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HHEMLNNI_02112 8.99e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HHEMLNNI_02113 2.84e-149 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHEMLNNI_02114 4.58e-140 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HHEMLNNI_02115 6.89e-296 hisD 1.1.1.23, 1.1.1.308 - E ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHEMLNNI_02116 3.55e-146 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HHEMLNNI_02117 1.15e-280 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HHEMLNNI_02118 2.68e-110 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HHEMLNNI_02119 1.4e-152 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HHEMLNNI_02120 1.44e-206 yvoD - - P - - - COG0370 Fe2 transport system protein B
HHEMLNNI_02121 4.33e-197 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHEMLNNI_02122 3.78e-219 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHEMLNNI_02123 3.6e-64 yvlD - - S ko:K08972 - ko00000 Membrane
HHEMLNNI_02125 2.85e-204 yvlB - - S - - - Putative adhesin
HHEMLNNI_02126 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHEMLNNI_02127 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHEMLNNI_02128 3.9e-218 yoaV3 - - EG - - - EamA-like transporter family
HHEMLNNI_02129 2.62e-264 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHEMLNNI_02130 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HHEMLNNI_02131 3.78e-178 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 peptidase
HHEMLNNI_02132 7.66e-195 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HHEMLNNI_02133 7.42e-161 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HHEMLNNI_02134 4.99e-193 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HHEMLNNI_02135 1.24e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHEMLNNI_02136 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHEMLNNI_02137 3.01e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHEMLNNI_02138 6.79e-42 cspC - - K ko:K03704 - ko00000,ko03000 cold-shock protein
HHEMLNNI_02139 7.77e-198 - - - - - - - -
HHEMLNNI_02141 4.42e-87 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HHEMLNNI_02142 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHEMLNNI_02143 3.19e-66 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HHEMLNNI_02144 1.67e-46 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HHEMLNNI_02145 1e-101 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HHEMLNNI_02146 4.08e-247 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HHEMLNNI_02147 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HHEMLNNI_02148 1.12e-07 yvyG - - NOU - - - Flagellar biosynthesis protein FlgN
HHEMLNNI_02149 6.14e-53 - - - N ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Anti-sigma-28 factor, FlgM
HHEMLNNI_02150 5.44e-99 yvyF - - S - - - flagellar protein
HHEMLNNI_02151 8.38e-169 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HHEMLNNI_02152 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HHEMLNNI_02153 7.77e-197 degV - - S - - - protein conserved in bacteria
HHEMLNNI_02154 4.63e-162 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHEMLNNI_02155 6.87e-257 degS 2.7.13.3 - T ko:K07683,ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HHEMLNNI_02156 1.99e-151 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HHEMLNNI_02157 9.6e-101 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HHEMLNNI_02158 2.98e-26 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HHEMLNNI_02159 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HHEMLNNI_02160 8.72e-203 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 binding-protein-dependent transport systems inner membrane component
HHEMLNNI_02161 4.99e-225 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_02162 5.46e-192 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_02163 2.28e-248 oppD - - P ko:K02031,ko:K16202 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_02164 2.96e-105 - - - K ko:K03718 - ko00000,ko03000 helix_turn_helix ASNC type
HHEMLNNI_02165 4.43e-251 ywtF_2 - - K - - - Transcriptional regulator
HHEMLNNI_02168 2.57e-89 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_02169 3.17e-45 imm - - S - - - Colicin-E5 Imm protein
HHEMLNNI_02170 2.3e-06 - - - S - - - Fur-regulated basic protein B
HHEMLNNI_02171 3.93e-17 sspN - - S ko:K06431 - ko00000 Small acid-soluble spore protein N family
HHEMLNNI_02172 2.54e-184 - - - P ko:K07245 - ko00000,ko02000 Copper resistance protein D
HHEMLNNI_02173 0.0 spoVK_1 - - O - - - stage V sporulation protein K
HHEMLNNI_02174 1.02e-98 yneP - - S ko:K07107 - ko00000,ko01000 thioesterase
HHEMLNNI_02175 8.79e-199 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHEMLNNI_02176 4.11e-105 - - - S - - - Domain of unknown function (DUF4352)
HHEMLNNI_02177 2.03e-230 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HHEMLNNI_02178 5.7e-199 - - - I - - - Hydrolase
HHEMLNNI_02179 8.65e-298 ykuI - - T - - - Diguanylate phosphodiesterase
HHEMLNNI_02180 1.81e-31 - - - - - - - -
HHEMLNNI_02181 1.03e-47 - - - S - - - YppG-like protein
HHEMLNNI_02182 6.63e-95 hspX - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HHEMLNNI_02183 3.8e-222 - 3.4.13.19 - E ko:K01273 - ko00000,ko00537,ko01000,ko01002,ko04147 COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
HHEMLNNI_02184 7.84e-207 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HHEMLNNI_02186 3.64e-70 yneR - - S - - - Belongs to the HesB IscA family
HHEMLNNI_02187 1.22e-125 msrA 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHEMLNNI_02188 1.57e-280 - - - I ko:K01066 - ko00000,ko01000 COG0657 Esterase lipase
HHEMLNNI_02189 3.94e-58 - - - S - - - DNA alkylation repair protein
HHEMLNNI_02190 7.16e-236 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HHEMLNNI_02191 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHEMLNNI_02192 5.73e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HHEMLNNI_02193 1.27e-66 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HHEMLNNI_02194 5.71e-58 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HHEMLNNI_02195 1.95e-57 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HHEMLNNI_02196 0.0 agcS - - E ko:K03310 - ko00000 Sodium alanine symporter
HHEMLNNI_02197 7.49e-301 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HHEMLNNI_02198 8.12e-165 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HHEMLNNI_02199 4.65e-100 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HHEMLNNI_02200 1.51e-161 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HHEMLNNI_02201 1.13e-123 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HHEMLNNI_02203 1.24e-137 - - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HHEMLNNI_02204 8.08e-259 - - - T - - - Histidine kinase
HHEMLNNI_02205 3.25e-154 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HHEMLNNI_02206 4.58e-162 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HHEMLNNI_02207 1.24e-218 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HHEMLNNI_02209 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHEMLNNI_02210 1.36e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HHEMLNNI_02212 3.88e-153 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 lytic transglycosylase activity
HHEMLNNI_02213 2.23e-260 - - - Q - - - O-methyltransferase
HHEMLNNI_02215 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HHEMLNNI_02216 2.1e-260 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HHEMLNNI_02217 9.15e-45 yozC - - - - - - -
HHEMLNNI_02218 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHEMLNNI_02219 5.3e-201 yvgN - - S - - - reductase
HHEMLNNI_02220 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HHEMLNNI_02221 1.32e-74 ytxJ - - O - - - Protein of unknown function (DUF2847)
HHEMLNNI_02222 1.09e-118 yocC - - - - - - -
HHEMLNNI_02223 1.3e-135 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HHEMLNNI_02224 3.76e-215 - 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 Helix-hairpin-helix class 2 (Pol1 family) motifs
HHEMLNNI_02225 1.15e-160 bshB2 - - S ko:K22135 - ko00000,ko01000 deacetylase
HHEMLNNI_02226 9.83e-81 yojF - - S - - - Protein of unknown function (DUF1806)
HHEMLNNI_02227 4.16e-149 mucD 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHEMLNNI_02228 1.92e-92 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HHEMLNNI_02230 2.44e-305 ydbM - - I - - - acyl-CoA dehydrogenase
HHEMLNNI_02231 6.53e-307 - - - S - - - membrane
HHEMLNNI_02232 3.74e-69 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_02233 8.16e-160 - - - - - - - -
HHEMLNNI_02234 5.07e-134 - - - - - - - -
HHEMLNNI_02237 4.45e-128 - - - S - - - DinB superfamily
HHEMLNNI_02238 5.68e-83 - - - - - - - -
HHEMLNNI_02239 9.45e-181 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HHEMLNNI_02240 0.0 - 2.7.1.199, 2.7.1.208 - G ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_02241 0.0 - 4.3.2.2, 5.5.1.2 - F ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminus
HHEMLNNI_02242 1.72e-162 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HHEMLNNI_02245 4.03e-23 - - - - - - - -
HHEMLNNI_02247 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HHEMLNNI_02248 8.7e-178 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
HHEMLNNI_02249 0.0 glvA 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHEMLNNI_02250 9.73e-165 - - - K ko:K11922 - ko00000,ko03000 UTRA
HHEMLNNI_02251 1.4e-147 - - - S - - - CAAX protease self-immunity
HHEMLNNI_02252 1.84e-246 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HHEMLNNI_02253 2.66e-215 ydhU - - P ko:K07217 - ko00000 Catalase
HHEMLNNI_02254 1.02e-194 - - - S - - - Nucleotidyltransferase domain
HHEMLNNI_02255 4.17e-37 - - - - - - - -
HHEMLNNI_02256 1.06e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HHEMLNNI_02257 1.71e-257 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HHEMLNNI_02258 5.56e-268 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHEMLNNI_02259 4.46e-228 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHEMLNNI_02260 2.4e-195 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HHEMLNNI_02261 1.67e-218 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HHEMLNNI_02262 4.86e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HHEMLNNI_02263 2.31e-229 - - - S - - - Tetratricopeptide repeat
HHEMLNNI_02264 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HHEMLNNI_02265 3.83e-316 mtaD 3.5.4.28, 3.5.4.31 - F ko:K12960 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HHEMLNNI_02267 8.74e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HHEMLNNI_02268 2.1e-109 ypmB - - S - - - protein conserved in bacteria
HHEMLNNI_02269 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HHEMLNNI_02270 6.12e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HHEMLNNI_02271 2.51e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHEMLNNI_02272 0.0 ypbR - - S - - - Dynamin family
HHEMLNNI_02273 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HHEMLNNI_02274 2.96e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHEMLNNI_02275 5.81e-218 yppC - - S - - - Protein of unknown function (DUF2515)
HHEMLNNI_02277 1.92e-118 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HHEMLNNI_02278 4.37e-81 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HHEMLNNI_02279 2.9e-26 - - - - - - - -
HHEMLNNI_02280 6.68e-302 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHEMLNNI_02281 1.4e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HHEMLNNI_02282 1.32e-220 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHEMLNNI_02283 2.31e-73 yusE - - CO - - - cell redox homeostasis
HHEMLNNI_02284 1.09e-100 yphP - - S - - - Belongs to the UPF0403 family
HHEMLNNI_02285 1.03e-96 - - - CO - - - Thioredoxin-like
HHEMLNNI_02286 1.7e-176 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
HHEMLNNI_02287 2.15e-201 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HHEMLNNI_02288 5.49e-42 - - - - - - - -
HHEMLNNI_02289 4.28e-112 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HHEMLNNI_02290 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HHEMLNNI_02291 7.61e-247 - - - S - - - Protein of unknown function (DUF2777)
HHEMLNNI_02292 8.81e-215 - - - - - - - -
HHEMLNNI_02293 4.78e-198 telA - - P - - - Belongs to the TelA family
HHEMLNNI_02295 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HHEMLNNI_02296 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HHEMLNNI_02297 2.85e-147 ypjP - - S - - - YpjP-like protein
HHEMLNNI_02298 3.24e-53 - - - - - - - -
HHEMLNNI_02299 9.99e-86 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HHEMLNNI_02300 1.46e-207 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHEMLNNI_02301 2.9e-05 - - - S ko:K06376 - ko00000 Spo0E like sporulation regulatory protein
HHEMLNNI_02302 3.72e-116 - - - - - - - -
HHEMLNNI_02303 3.83e-197 ycsE - - S - - - hydrolases of the HAD superfamily
HHEMLNNI_02304 1.41e-28 - - - - - - - -
HHEMLNNI_02305 8.79e-239 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HHEMLNNI_02306 6.2e-148 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HHEMLNNI_02307 1.43e-130 - - - - - - - -
HHEMLNNI_02308 2.11e-272 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HHEMLNNI_02309 1.07e-242 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HHEMLNNI_02310 0.0 gerAA - - EG ko:K06288,ko:K06310 - ko00000 Spore germination protein
HHEMLNNI_02311 0.0 pepF - - E - - - oligoendopeptidase F
HHEMLNNI_02312 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HHEMLNNI_02313 8.95e-293 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HHEMLNNI_02314 3.55e-07 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
HHEMLNNI_02315 3.49e-127 ypsA - - S - - - Belongs to the UPF0398 family
HHEMLNNI_02316 2.65e-64 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHEMLNNI_02317 2.55e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
HHEMLNNI_02318 4.41e-270 - - - L ko:K07496 - ko00000 Transposase
HHEMLNNI_02319 6.68e-52 - - - - - - - -
HHEMLNNI_02320 6.65e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HHEMLNNI_02321 6.18e-238 - - - S - - - Oxidoreductase
HHEMLNNI_02322 0.0 - 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
HHEMLNNI_02323 1.04e-83 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HHEMLNNI_02324 6.96e-83 - - - - - - - -
HHEMLNNI_02325 4.28e-222 - - - NT - - - Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HHEMLNNI_02327 4.89e-241 - - - S ko:K06308 - ko00000 Spore germination B3/ GerAC like, C-terminal
HHEMLNNI_02328 6.28e-251 - - - E - - - Spore germination protein
HHEMLNNI_02329 0.0 - - - P - - - Spore gernimation protein GerA
HHEMLNNI_02330 3.06e-86 - - - S - - - Src homology 3 domains
HHEMLNNI_02331 1.12e-68 - - - - - - - -
HHEMLNNI_02332 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HHEMLNNI_02333 1.75e-28 - - - S - - - Protein of unknown function (DUF2564)
HHEMLNNI_02335 1.68e-276 - - - G - - - Transmembrane secretion effector
HHEMLNNI_02336 2.27e-122 - - - Q - - - ubiE/COQ5 methyltransferase family
HHEMLNNI_02337 6.83e-70 - - - S - - - Belongs to the HesB IscA family
HHEMLNNI_02338 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HHEMLNNI_02339 8.78e-130 - - - U - - - MarC family integral membrane protein
HHEMLNNI_02340 2.92e-188 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_02341 2.75e-245 opuBA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HHEMLNNI_02342 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HHEMLNNI_02343 1.03e-91 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HHEMLNNI_02344 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHEMLNNI_02345 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHEMLNNI_02346 1.57e-77 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2200)
HHEMLNNI_02347 3.54e-111 yocK - - T - - - general stress protein
HHEMLNNI_02348 1.97e-259 ytvI - - S - - - sporulation integral membrane protein YtvI
HHEMLNNI_02349 1.27e-172 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HHEMLNNI_02350 2.56e-180 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HHEMLNNI_02351 1.44e-194 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HHEMLNNI_02352 3.49e-149 - - - S - - - Golgi phosphoprotein 3 (GPP34)
HHEMLNNI_02353 1.01e-48 - - - K - - - COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
HHEMLNNI_02354 1.17e-138 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HHEMLNNI_02355 1.64e-161 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 This enzyme is an effector of chloramphenicol resistance in bacteria
HHEMLNNI_02356 1.84e-116 - - - C - - - HEAT repeats
HHEMLNNI_02357 2.88e-60 - - - S - - - Belongs to the LOG family
HHEMLNNI_02358 6.73e-86 - - - S - - - Bacterial PH domain
HHEMLNNI_02359 3.86e-236 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HHEMLNNI_02360 1.04e-39 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HHEMLNNI_02362 3.17e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HHEMLNNI_02363 9e-181 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HHEMLNNI_02364 7.29e-214 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_02365 6.14e-15 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HHEMLNNI_02366 1.46e-69 - - - - - - - -
HHEMLNNI_02367 3.16e-183 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HHEMLNNI_02368 6.15e-181 - - - - - - - -
HHEMLNNI_02369 2.8e-277 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HHEMLNNI_02370 1.34e-112 - - - S - - - Domain of unknown function (DUF4188)
HHEMLNNI_02371 4.21e-126 - - - K - - - Virulence activator alpha C-term
HHEMLNNI_02372 3.5e-206 - - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HHEMLNNI_02373 0.0 - - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHEMLNNI_02374 5.41e-08 - - - S - - - Putative methionine and alanine importer, small subunit
HHEMLNNI_02375 1.18e-72 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HHEMLNNI_02377 1.32e-193 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HHEMLNNI_02379 1.74e-160 yeeN - - K - - - transcriptional regulatory protein
HHEMLNNI_02380 6.97e-199 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HHEMLNNI_02381 1.89e-316 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HHEMLNNI_02382 6.21e-128 - 3.1.3.82, 3.1.3.83 - E ko:K03273 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 D,D-heptose 1,7-bisphosphate phosphatase
HHEMLNNI_02383 2.09e-208 asbF 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
HHEMLNNI_02384 3.83e-242 asbE - - IQ - - - Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHEMLNNI_02385 1.56e-55 asbD - - IQ - - - Phosphopantetheine attachment site
HHEMLNNI_02386 4.9e-303 asbC - - IQ ko:K00666 - ko00000,ko01000,ko01004 AMP-binding enzyme C-terminal domain
HHEMLNNI_02387 0.0 asbB - - Q - - - IucA / IucC family
HHEMLNNI_02388 0.0 asbA - - Q - - - Siderophore biosynthesis protein
HHEMLNNI_02389 2.97e-76 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HHEMLNNI_02390 3.92e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HHEMLNNI_02391 3.23e-219 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HHEMLNNI_02392 5.29e-238 ywcH1 - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHEMLNNI_02393 9.74e-176 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HHEMLNNI_02394 8.75e-236 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHEMLNNI_02395 1.21e-135 yvdT - - K - - - Transcriptional regulator
HHEMLNNI_02396 9.41e-300 - - - S - - - Acetyltransferase
HHEMLNNI_02397 1.28e-151 - - CBM50 M ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HHEMLNNI_02398 7.37e-139 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HHEMLNNI_02399 4.57e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HHEMLNNI_02400 1.62e-186 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HHEMLNNI_02401 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HHEMLNNI_02402 7.48e-133 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HHEMLNNI_02403 3.86e-195 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HHEMLNNI_02404 6.95e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HHEMLNNI_02405 4.7e-204 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHEMLNNI_02406 3.36e-231 - - - M - - - 3D domain
HHEMLNNI_02407 2.6e-204 - - - M - - - 3D domain
HHEMLNNI_02408 4.48e-171 yodH - - Q - - - Methyltransferase
HHEMLNNI_02409 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHEMLNNI_02410 3.05e-126 - - - S - - - Protein of unknown function (DUF1706)
HHEMLNNI_02411 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHEMLNNI_02413 3.68e-69 - - - - - - - -
HHEMLNNI_02414 6.65e-183 - - - Q - - - Methyltransferase domain
HHEMLNNI_02415 7.39e-98 yyaT - - S - - - Acetyltransferase (GNAT) domain
HHEMLNNI_02416 3.33e-51 - - - - - - - -
HHEMLNNI_02417 9.11e-302 hint 6.5.1.3 - S ko:K14415 - ko00000,ko01000,ko03016 tRNA-splicing ligase RtcB
HHEMLNNI_02418 9.74e-98 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HHEMLNNI_02419 1.23e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHEMLNNI_02420 2.69e-79 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HHEMLNNI_02421 3.86e-202 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HHEMLNNI_02422 1.26e-270 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HHEMLNNI_02423 2.45e-151 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HHEMLNNI_02424 1.1e-180 - - - S - - - Sporulation protein YpjB (SpoYpjB)
HHEMLNNI_02425 1.8e-141 ypjA - - S - - - membrane
HHEMLNNI_02426 2.15e-192 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HHEMLNNI_02427 8.39e-159 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HHEMLNNI_02428 3.64e-119 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HHEMLNNI_02429 3.7e-106 ypiF - - S - - - Protein of unknown function (DUF2487)
HHEMLNNI_02430 4.13e-127 ypiB - - S - - - Belongs to the UPF0302 family
HHEMLNNI_02431 7.94e-294 ypiA - - S - - - COG0457 FOG TPR repeat
HHEMLNNI_02432 2.85e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HHEMLNNI_02433 4.68e-259 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HHEMLNNI_02434 3.6e-265 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HHEMLNNI_02435 5.66e-189 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HHEMLNNI_02436 1.47e-286 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HHEMLNNI_02437 1.29e-150 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosylanthranilate isomerase activity
HHEMLNNI_02438 3.1e-170 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HHEMLNNI_02439 7.49e-237 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHEMLNNI_02440 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHEMLNNI_02441 6.53e-77 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HHEMLNNI_02442 6.84e-253 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HHEMLNNI_02443 3.58e-281 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHEMLNNI_02444 1.39e-185 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HHEMLNNI_02445 6.26e-101 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HHEMLNNI_02446 2.93e-234 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HHEMLNNI_02447 1.72e-207 mqnA 4.2.1.151 - S ko:K11782 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HHEMLNNI_02448 4.87e-203 ubiA 2.5.1.39 - H ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HHEMLNNI_02449 3.84e-170 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HHEMLNNI_02450 4.74e-73 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 heptaprenyl diphosphate synthase
HHEMLNNI_02451 1.85e-48 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HHEMLNNI_02452 4.09e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HHEMLNNI_02453 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HHEMLNNI_02454 6.76e-174 yphF - - - - - - -
HHEMLNNI_02455 8.81e-10 yphE - - S - - - Protein of unknown function (DUF2768)
HHEMLNNI_02456 5.25e-54 - - - S - - - Stage VI sporulation protein F
HHEMLNNI_02457 1.2e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HHEMLNNI_02458 3.54e-133 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHEMLNNI_02459 1.89e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HHEMLNNI_02461 6.14e-260 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HHEMLNNI_02462 4.75e-138 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 1-acyl-sn-glycerol-3-phosphate acyltransferase
HHEMLNNI_02463 1.2e-169 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HHEMLNNI_02464 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HHEMLNNI_02465 4.76e-215 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HHEMLNNI_02466 0.0 metH 2.1.1.13 - E ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HHEMLNNI_02467 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HHEMLNNI_02468 2.44e-267 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HHEMLNNI_02469 8.25e-36 - - - - - - - -
HHEMLNNI_02470 2.05e-146 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HHEMLNNI_02471 1.05e-230 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HHEMLNNI_02472 1.5e-231 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HHEMLNNI_02473 7.53e-304 gudB 1.4.1.2, 1.4.1.4 - E ko:K00260,ko:K00262 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HHEMLNNI_02474 2.45e-245 - - - - - - - -
HHEMLNNI_02475 0.0 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HHEMLNNI_02476 5.68e-164 - - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_02477 8.17e-141 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HHEMLNNI_02478 2.2e-221 ycgE - - K ko:K22491 - ko00000,ko03000 MerR family transcriptional regulator
HHEMLNNI_02479 3.54e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HHEMLNNI_02480 1.59e-288 - - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HHEMLNNI_02482 1.94e-229 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHEMLNNI_02483 5e-253 - - GT4 M ko:K13678 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HHEMLNNI_02484 6.52e-289 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl Transferase
HHEMLNNI_02486 3.14e-52 - - - K - - - Helix-turn-helix XRE-family like proteins
HHEMLNNI_02487 7.55e-69 - - - K - - - Helix-turn-helix XRE-family like proteins
HHEMLNNI_02490 1.04e-134 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HHEMLNNI_02491 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HHEMLNNI_02492 1.11e-242 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HHEMLNNI_02493 2.28e-57 fer - - C ko:K05337 - ko00000 Ferredoxin
HHEMLNNI_02494 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHEMLNNI_02495 0.0 nox 1.11.1.1 - P ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HHEMLNNI_02496 5e-175 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HHEMLNNI_02498 6.84e-127 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HHEMLNNI_02499 8.64e-179 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HHEMLNNI_02500 1.06e-239 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_02502 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_02503 2.69e-167 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_02504 1.35e-282 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HHEMLNNI_02505 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HHEMLNNI_02506 5.06e-126 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HHEMLNNI_02507 3.81e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HHEMLNNI_02508 2.1e-104 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HHEMLNNI_02509 8.76e-131 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HHEMLNNI_02510 2.21e-274 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HHEMLNNI_02511 1.46e-73 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
HHEMLNNI_02512 5.15e-247 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HHEMLNNI_02513 5.44e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HHEMLNNI_02514 1.09e-58 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHEMLNNI_02515 1.56e-161 - - - S - - - membrane
HHEMLNNI_02516 9.37e-60 - - - S - - - ATP synthase, subunit b
HHEMLNNI_02517 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HHEMLNNI_02518 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHEMLNNI_02519 9.28e-218 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HHEMLNNI_02520 0.0 acoD - - C ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family
HHEMLNNI_02521 4.98e-137 - - - K - - - Uncharacterized protein conserved in bacteria (DUF2087)
HHEMLNNI_02522 3.87e-126 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHEMLNNI_02523 3.26e-177 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHEMLNNI_02524 2.61e-110 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HHEMLNNI_02525 3.42e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HHEMLNNI_02526 6.5e-289 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HHEMLNNI_02527 2.59e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HHEMLNNI_02528 1.05e-251 - - - I - - - 3-hydroxyisobutyryl-CoA hydrolase
HHEMLNNI_02529 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHEMLNNI_02530 5.09e-208 hgd 1.1.1.31, 1.1.1.60 - I ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 ko00000,ko00001,ko01000 3-hydroxyisobutyrate dehydrogenase
HHEMLNNI_02531 1.35e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HHEMLNNI_02532 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HHEMLNNI_02533 1.47e-266 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HHEMLNNI_02534 9.81e-259 - - - S - - - Psort location CytoplasmicMembrane, score
HHEMLNNI_02536 8.12e-204 ccpC - - K - - - Transcriptional regulator
HHEMLNNI_02537 4.61e-106 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHEMLNNI_02538 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHEMLNNI_02539 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HHEMLNNI_02540 5.35e-139 spoVAEA - - S ko:K06407 - ko00000 Stage V sporulation protein AE
HHEMLNNI_02541 8.69e-76 - - - S ko:K06407 - ko00000 Pfam:SpoVA
HHEMLNNI_02542 2.93e-235 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HHEMLNNI_02543 7.14e-105 - - - S ko:K06405 - ko00000 Pfam:SpoVA
HHEMLNNI_02544 9.34e-176 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHEMLNNI_02545 1.32e-97 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HHEMLNNI_02546 7.27e-73 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HHEMLNNI_02547 2.05e-276 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HHEMLNNI_02548 6.53e-182 - 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HHEMLNNI_02549 2.22e-108 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HHEMLNNI_02550 6.09e-72 - - - - - - - -
HHEMLNNI_02551 9.12e-29 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HHEMLNNI_02552 9.25e-306 ycnB - - EGP - - - the major facilitator superfamily
HHEMLNNI_02553 3.72e-154 - - - J - - - translation release factor activity
HHEMLNNI_02554 4.19e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
HHEMLNNI_02555 8.13e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HHEMLNNI_02556 3.47e-287 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHEMLNNI_02557 1.87e-217 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HHEMLNNI_02558 8.77e-19 - - - S - - - Protein of unknown function (DUF4227)
HHEMLNNI_02559 3.11e-111 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HHEMLNNI_02560 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HHEMLNNI_02561 1.1e-121 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HHEMLNNI_02563 8.65e-116 - - - CO - - - Thioredoxin-like
HHEMLNNI_02564 2.65e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHEMLNNI_02565 1.73e-270 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HHEMLNNI_02566 9.24e-122 - - - S - - - UPF0316 protein
HHEMLNNI_02567 2.45e-109 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HHEMLNNI_02568 2.49e-128 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HHEMLNNI_02569 1.08e-71 ogt - - L ko:K07443 - ko00000 Methyltransferase
HHEMLNNI_02570 3.54e-110 - - - V - - - COG4767 Glycopeptide antibiotics resistance protein
HHEMLNNI_02571 1.71e-239 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HHEMLNNI_02572 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HHEMLNNI_02573 1.77e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHEMLNNI_02574 5.59e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HHEMLNNI_02575 5.57e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHEMLNNI_02576 2.33e-167 - - - P ko:K08714 - ko00000,ko02000 Polycystin cation channel
HHEMLNNI_02577 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HHEMLNNI_02579 6.24e-66 - - - - - - - -
HHEMLNNI_02580 3.57e-62 tnrA - - K - - - transcriptional
HHEMLNNI_02581 8.08e-192 yibQ - - S ko:K09798 - ko00000 protein conserved in bacteria
HHEMLNNI_02582 0.0 apr - - O - - - Belongs to the peptidase S8 family
HHEMLNNI_02583 1.75e-56 - - - - - - - -
HHEMLNNI_02584 7.62e-97 ykuL - - S - - - CBS domain
HHEMLNNI_02585 5.51e-106 - - - S - - - Pfam Polyketide cyclase dehydrase and lipid transport
HHEMLNNI_02586 1e-91 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HHEMLNNI_02589 4.46e-255 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HHEMLNNI_02590 7.23e-93 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HHEMLNNI_02592 6.58e-122 yqjB - - S - - - protein conserved in bacteria
HHEMLNNI_02593 1.92e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HHEMLNNI_02594 1.23e-225 - - - F - - - GHKL domain
HHEMLNNI_02595 6.5e-119 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHEMLNNI_02596 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HHEMLNNI_02597 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHEMLNNI_02598 2.58e-41 - - - K - - - Cro/C1-type HTH DNA-binding domain
HHEMLNNI_02599 2.49e-67 - - - K - - - Helix-turn-helix XRE-family like proteins
HHEMLNNI_02600 4.16e-42 - - - - - - - -
HHEMLNNI_02601 8.4e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HHEMLNNI_02602 1.25e-123 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HHEMLNNI_02603 2.24e-101 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHEMLNNI_02604 5.85e-250 yqgV - - S - - - Thiamine-binding protein
HHEMLNNI_02605 7.96e-127 - - - - - - - -
HHEMLNNI_02606 6.29e-183 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HHEMLNNI_02607 1.79e-269 thiO 1.4.3.19 - E ko:K03153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HHEMLNNI_02608 1.74e-180 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HHEMLNNI_02609 4.45e-38 - - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
HHEMLNNI_02610 9.41e-140 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HHEMLNNI_02611 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HHEMLNNI_02612 1.39e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HHEMLNNI_02613 8.32e-12 yqgQ - - S - - - protein conserved in bacteria
HHEMLNNI_02614 6.67e-109 - - - - - - - -
HHEMLNNI_02615 3.51e-88 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HHEMLNNI_02616 0.0 spoVAF - - EG ko:K06408 - ko00000 Bacillus/Clostridium GerA spore germination protein
HHEMLNNI_02617 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HHEMLNNI_02619 1.33e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HHEMLNNI_02620 2.54e-242 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HHEMLNNI_02621 1.96e-183 - - - S - - - Integral membrane protein DUF92
HHEMLNNI_02622 5.82e-130 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHEMLNNI_02623 6.04e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HHEMLNNI_02624 3.68e-161 - - - G - - - PFAM Glycoside hydrolase 15-related
HHEMLNNI_02625 2.23e-80 - - - - - - - -
HHEMLNNI_02626 4.99e-101 - - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHEMLNNI_02627 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
HHEMLNNI_02628 3.71e-298 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HHEMLNNI_02629 1.93e-149 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HHEMLNNI_02635 0.0 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HHEMLNNI_02636 1.38e-252 XK27_00915 - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHEMLNNI_02637 6.09e-152 - - - O - - - NfeD-like C-terminal, partner-binding
HHEMLNNI_02638 1.61e-196 ypuA - - S - - - Secreted protein
HHEMLNNI_02639 8.7e-244 - - - EGP ko:K08221 - ko00000,ko02000 Sugar (and other) transporter
HHEMLNNI_02640 2.73e-79 fimV - - NU ko:K08086,ko:K15845 ko05120,map05120 ko00000,ko00001 translation initiation factor activity
HHEMLNNI_02641 6.11e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HHEMLNNI_02642 1.19e-88 yqfX - - S - - - membrane
HHEMLNNI_02643 1.54e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HHEMLNNI_02644 1.04e-49 - - - S - - - Domain of Unknown Function (DUF1540)
HHEMLNNI_02645 3.86e-102 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HHEMLNNI_02646 3.3e-183 zurM - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HHEMLNNI_02647 1.19e-184 zurA - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HHEMLNNI_02648 1.14e-168 - - - M - - - Transglycosylase SLT domain
HHEMLNNI_02649 2.78e-274 - - - T - - - His Kinase A (phosphoacceptor) domain
HHEMLNNI_02651 2.64e-210 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HHEMLNNI_02652 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHEMLNNI_02653 2.31e-104 yqfQ - - S - - - YqfQ-like protein
HHEMLNNI_02654 1.65e-111 - - - K ko:K07736 - ko00000,ko03000 Transcription factor
HHEMLNNI_02655 2.59e-228 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HHEMLNNI_02656 2.79e-255 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHEMLNNI_02657 3.37e-177 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HHEMLNNI_02658 4.86e-84 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HHEMLNNI_02659 1.45e-257 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHEMLNNI_02660 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHEMLNNI_02661 1.57e-102 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HHEMLNNI_02662 1.01e-183 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HHEMLNNI_02663 1.56e-145 ccpN - - K - - - CBS domain
HHEMLNNI_02664 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HHEMLNNI_02665 1.18e-219 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HHEMLNNI_02667 3.16e-184 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HHEMLNNI_02668 2.53e-25 - - - S - - - YqzL-like protein
HHEMLNNI_02669 1.22e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHEMLNNI_02670 2.32e-94 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HHEMLNNI_02671 4.46e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HHEMLNNI_02672 1.68e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHEMLNNI_02673 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HHEMLNNI_02674 1.6e-221 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HHEMLNNI_02675 4.2e-284 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HHEMLNNI_02676 1.73e-63 yqfC - - S - - - sporulation protein YqfC
HHEMLNNI_02677 9.8e-107 - - - - - - - -
HHEMLNNI_02678 1.79e-156 yqfA - - S - - - UPF0365 protein
HHEMLNNI_02679 1.21e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HHEMLNNI_02680 3.29e-94 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HHEMLNNI_02681 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HHEMLNNI_02682 4.15e-206 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HHEMLNNI_02683 6.97e-96 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HHEMLNNI_02684 6.31e-108 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HHEMLNNI_02685 2.11e-148 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHEMLNNI_02686 5.29e-282 gltT - - C - - - Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHEMLNNI_02687 9.74e-178 - - - Q - - - ubiE/COQ5 methyltransferase family
HHEMLNNI_02688 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HHEMLNNI_02689 8.6e-169 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHEMLNNI_02690 1.49e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HHEMLNNI_02691 2.02e-268 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHEMLNNI_02692 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HHEMLNNI_02693 3.52e-113 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHEMLNNI_02694 2.95e-239 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHEMLNNI_02695 9.47e-282 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HHEMLNNI_02696 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHEMLNNI_02697 7.24e-69 - - - - - - - -
HHEMLNNI_02698 2.26e-266 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HHEMLNNI_02699 1.25e-262 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHEMLNNI_02700 1.15e-48 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HHEMLNNI_02701 2.59e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HHEMLNNI_02702 9.62e-09 - - - S - - - YqzM-like protein
HHEMLNNI_02703 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HHEMLNNI_02704 8.89e-143 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HHEMLNNI_02705 1.51e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HHEMLNNI_02706 3.69e-193 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHEMLNNI_02707 1.15e-181 - - - S - - - Methyltransferase domain
HHEMLNNI_02708 5.98e-208 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HHEMLNNI_02709 5.25e-81 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHEMLNNI_02710 8.56e-140 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HHEMLNNI_02711 7.06e-138 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHEMLNNI_02712 3.75e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HHEMLNNI_02713 6.15e-196 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HHEMLNNI_02714 4.12e-277 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HHEMLNNI_02715 1.52e-125 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HHEMLNNI_02717 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HHEMLNNI_02718 1.09e-95 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHEMLNNI_02719 1.13e-66 mnhC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHEMLNNI_02720 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHEMLNNI_02721 1.54e-106 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHEMLNNI_02722 4.41e-52 - - - P ko:K05570 - ko00000,ko02000 Multiple resistance and pH regulation protein F (MrpF / PhaF)
HHEMLNNI_02723 1.19e-88 - - - P ko:K05571 - ko00000,ko02000 Na+/H+ antiporter subunit
HHEMLNNI_02724 5.78e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHEMLNNI_02725 1.76e-195 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 - H ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HHEMLNNI_02727 0.0 - - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HHEMLNNI_02728 9.13e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HHEMLNNI_02729 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHEMLNNI_02730 0.0 nirB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HHEMLNNI_02731 1.51e-73 nirD 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HHEMLNNI_02732 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HHEMLNNI_02733 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HHEMLNNI_02734 1.15e-70 - - - - - - - -
HHEMLNNI_02736 2.71e-35 - - - - - - - -
HHEMLNNI_02737 1.27e-159 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHEMLNNI_02738 7.53e-215 ybaS - - S - - - Na -dependent transporter
HHEMLNNI_02739 2.43e-285 hipO3 - - S ko:K12941,ko:K21613 - ko00000,ko01000,ko01002 amidohydrolase
HHEMLNNI_02740 0.0 - - - S - - - Membrane
HHEMLNNI_02741 3.46e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HHEMLNNI_02742 6.21e-147 XK27_06885 - - L - - - COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HHEMLNNI_02743 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Starch/carbohydrate-binding module (family 53)
HHEMLNNI_02744 6.95e-139 arpR - - K - - - Bacterial regulatory proteins, tetR family
HHEMLNNI_02745 4.06e-195 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_02746 3.17e-205 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
HHEMLNNI_02747 4.46e-185 - - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HHEMLNNI_02748 7.14e-191 - - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HHEMLNNI_02749 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HHEMLNNI_02750 7.57e-103 - - - - - - - -
HHEMLNNI_02752 8.69e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHEMLNNI_02753 2.91e-191 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HHEMLNNI_02754 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HHEMLNNI_02755 2.42e-17 yrrS - - S - - - Protein of unknown function (DUF1510)
HHEMLNNI_02756 8.99e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHEMLNNI_02757 6.91e-149 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HHEMLNNI_02758 1.19e-150 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HHEMLNNI_02759 2.1e-269 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHEMLNNI_02760 1.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
HHEMLNNI_02761 2.3e-96 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHEMLNNI_02762 6.53e-58 yrzL - - S - - - Belongs to the UPF0297 family
HHEMLNNI_02763 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHEMLNNI_02764 4.34e-240 yrrI - - S - - - AI-2E family transporter
HHEMLNNI_02765 1.11e-41 yrzR - - - - - - -
HHEMLNNI_02766 4.85e-107 yrrD - - S - - - protein conserved in bacteria
HHEMLNNI_02767 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHEMLNNI_02768 1.7e-65 yrrB - - S - - - COG0457 FOG TPR repeat
HHEMLNNI_02769 2.57e-276 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHEMLNNI_02770 4.81e-274 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HHEMLNNI_02771 2.93e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_02772 4.87e-298 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HHEMLNNI_02773 3.15e-138 rsfA - - S ko:K06314 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_02774 3.52e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HHEMLNNI_02775 1.05e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HHEMLNNI_02776 5.89e-66 - - - - - - - -
HHEMLNNI_02777 3.59e-281 - 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HHEMLNNI_02778 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HHEMLNNI_02779 2.37e-308 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HHEMLNNI_02781 9.73e-279 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HHEMLNNI_02782 8.24e-248 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_02783 9.13e-185 thuA - - G - - - Trehalose utilisation
HHEMLNNI_02784 5.96e-240 - - - K - - - LacI family transcriptional regulator
HHEMLNNI_02785 1.32e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHEMLNNI_02786 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHEMLNNI_02787 4.03e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHEMLNNI_02788 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HHEMLNNI_02789 7.21e-53 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HHEMLNNI_02790 2.96e-196 secF - - U ko:K03074,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHEMLNNI_02791 5.23e-295 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHEMLNNI_02792 2.15e-29 yrzD - - S - - - Post-transcriptional regulator
HHEMLNNI_02793 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHEMLNNI_02794 1.13e-44 yodI - - - - - - -
HHEMLNNI_02795 1.34e-103 - - - S - - - membrane
HHEMLNNI_02796 3.57e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
HHEMLNNI_02797 1.92e-51 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HHEMLNNI_02798 6.48e-291 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HHEMLNNI_02799 4.07e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHEMLNNI_02800 7.27e-38 yrzS - - S - - - Protein of unknown function (DUF2905)
HHEMLNNI_02801 2.23e-234 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHEMLNNI_02802 1.41e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHEMLNNI_02803 6.18e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HHEMLNNI_02804 7.85e-84 - 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 cytochrome c oxidase subunit II
HHEMLNNI_02805 1.44e-25 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHEMLNNI_02806 4.59e-272 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HHEMLNNI_02807 4.39e-268 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HHEMLNNI_02808 5.03e-194 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HHEMLNNI_02809 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HHEMLNNI_02810 2.54e-266 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HHEMLNNI_02811 2.02e-117 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HHEMLNNI_02812 1.11e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HHEMLNNI_02813 3.91e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HHEMLNNI_02814 5.03e-295 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHEMLNNI_02815 1.05e-130 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HHEMLNNI_02817 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HHEMLNNI_02818 2.06e-233 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HHEMLNNI_02819 5.06e-260 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HHEMLNNI_02820 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HHEMLNNI_02821 1.59e-156 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HHEMLNNI_02822 6.61e-167 ecsC - - S - - - EcsC protein family
HHEMLNNI_02823 1.79e-287 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HHEMLNNI_02824 8.06e-177 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HHEMLNNI_02825 1.56e-98 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HHEMLNNI_02826 1.26e-267 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HHEMLNNI_02827 2.8e-72 yhaH - - D - - - gas vesicle protein
HHEMLNNI_02828 2.03e-141 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HHEMLNNI_02829 4.88e-140 - - - S - - - Protein conserved in bacteria
HHEMLNNI_02830 2.48e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HHEMLNNI_02831 1.72e-212 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHEMLNNI_02832 5.35e-95 yhaL - - S - - - Sporulation protein YhaL
HHEMLNNI_02833 4.85e-231 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HHEMLNNI_02834 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_02835 2.31e-162 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_02836 1.47e-66 - - - - - - - -
HHEMLNNI_02838 2.91e-201 yhaX - - S - - - hydrolases of the HAD superfamily
HHEMLNNI_02839 2.8e-72 yheA - - S - - - Belongs to the UPF0342 family
HHEMLNNI_02840 4.74e-266 yheB - - S - - - Belongs to the UPF0754 family
HHEMLNNI_02842 2.94e-31 - - - - - - - -
HHEMLNNI_02843 0.0 - - - M - - - cell wall anchor domain
HHEMLNNI_02844 2.18e-110 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HHEMLNNI_02845 6.62e-176 - - - Q - - - Methyltransferase domain
HHEMLNNI_02846 6.77e-177 - - - K - - - helix_turn_helix, mercury resistance
HHEMLNNI_02847 9.15e-206 - 2.7.1.190 - S ko:K17910 - ko00000,ko01000,ko01504 Protein of unknown function (DUF1679)
HHEMLNNI_02848 1.86e-150 - - - O - - - Sap, sulfolipid-1-addressing protein
HHEMLNNI_02849 3.12e-95 - - - - - - - -
HHEMLNNI_02850 7.71e-185 - - - K - - - MerR family transcriptional regulator
HHEMLNNI_02851 5.55e-212 - - - K - - - Acetyltransferase (GNAT) family
HHEMLNNI_02852 2.28e-240 - - - M - - - Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HHEMLNNI_02853 4.51e-175 - - - KT - - - Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding
HHEMLNNI_02855 3.96e-145 - - - S - - - Protein of unknown function (DUF2812)
HHEMLNNI_02856 1.9e-61 - - - K - - - Transcriptional regulator PadR-like family
HHEMLNNI_02857 7.76e-72 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HHEMLNNI_02858 2.07e-32 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
HHEMLNNI_02859 1.61e-91 - - - - - - - -
HHEMLNNI_02860 0.0 - - - S - - - Tripartite tricarboxylate transporter TctA family
HHEMLNNI_02861 8.32e-88 - - - S - - - Tripartite tricarboxylate transporter TctB family
HHEMLNNI_02862 1.83e-233 - - - S - - - Tripartite tricarboxylate transporter family receptor
HHEMLNNI_02863 9.79e-209 - 1.1.1.399, 1.1.1.95 - C ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHEMLNNI_02864 4.3e-258 - - - C ko:K19954 - ko00000,ko01000 alcohol dehydrogenase
HHEMLNNI_02865 1.2e-205 - 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHEMLNNI_02866 0.0 - - - K - - - Propionate catabolism activator
HHEMLNNI_02867 1.74e-99 - - - J - - - Acetyltransferase (GNAT) domain
HHEMLNNI_02868 4.95e-246 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HHEMLNNI_02869 6.19e-140 - - - E - - - GDSL-like Lipase/Acylhydrolase
HHEMLNNI_02870 0.0 gsiB_3 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HHEMLNNI_02871 1.95e-13 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HHEMLNNI_02879 5.59e-128 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HHEMLNNI_02880 6.9e-157 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HHEMLNNI_02881 6.84e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHEMLNNI_02882 3.74e-284 ybbR - - S - - - protein conserved in bacteria
HHEMLNNI_02883 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHEMLNNI_02885 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHEMLNNI_02886 4.36e-200 ybfI - - K - - - AraC-like ligand binding domain
HHEMLNNI_02887 7.07e-222 - - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HHEMLNNI_02888 1.13e-249 - - - V - - - Beta-lactamase
HHEMLNNI_02890 0.0 - - - S - - - Aminoglycoside phosphotransferase
HHEMLNNI_02891 8.26e-96 - - - K - - - SpoVT / AbrB like domain
HHEMLNNI_02892 6.4e-281 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HHEMLNNI_02893 1.1e-181 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_02894 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HHEMLNNI_02895 1.5e-157 - - - T - - - Transcriptional regulatory protein, C terminal
HHEMLNNI_02896 2.1e-245 - - - T - - - Histidine kinase-like ATPases
HHEMLNNI_02897 4.32e-148 - - - K - - - Bacterial regulatory proteins, tetR family
HHEMLNNI_02898 3.12e-291 - - - EGP - - - Transmembrane secretion effector
HHEMLNNI_02899 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HHEMLNNI_02900 1.74e-176 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HHEMLNNI_02901 4.39e-76 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HHEMLNNI_02902 2.95e-205 CcmA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_02903 4.64e-127 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HHEMLNNI_02904 7.13e-228 - 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHEMLNNI_02906 7.26e-192 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
HHEMLNNI_02907 0.0 mecR1 - - KTV ko:K02172,ko:K02547 ko01501,map01501 ko00000,ko00001,ko00002,ko01002,ko01504 BlaR1 peptidase M56
HHEMLNNI_02908 1.29e-83 blaI - - K ko:K02171,ko:K02546 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
HHEMLNNI_02909 3.69e-183 - - - H ko:K17882 - ko00000,ko01000,ko01504 KNTase C-terminal domain
HHEMLNNI_02910 4.01e-77 - - - K ko:K21903 - ko00000,ko03000 transcriptional
HHEMLNNI_02911 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HHEMLNNI_02912 3.91e-262 trkA - - P ko:K07222 - ko00000 Oxidoreductase
HHEMLNNI_02913 3.88e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HHEMLNNI_02914 6.21e-119 - - - - - - - -
HHEMLNNI_02915 1.75e-187 - - - Q - - - ubiE/COQ5 methyltransferase family
HHEMLNNI_02916 9.05e-232 - 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HHEMLNNI_02917 5.03e-157 - - - Q - - - SAM-dependent methyltransferase
HHEMLNNI_02918 9.97e-186 - - - EG - - - EamA-like transporter family
HHEMLNNI_02919 1.63e-166 - - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHEMLNNI_02920 1.66e-146 - - - K - - - Acetyltransferase (GNAT) domain
HHEMLNNI_02921 4.71e-87 - - - - - - - -
HHEMLNNI_02922 9.99e-93 - - - S - - - Protein of unknown function (DUF2512)
HHEMLNNI_02923 1.21e-148 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HHEMLNNI_02924 6.88e-112 - 2.3.1.128 - J ko:K03789,ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HHEMLNNI_02925 0.0 - - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HHEMLNNI_02926 3.84e-153 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HHEMLNNI_02927 2.35e-211 ycgS - - I - - - alpha/beta hydrolase fold
HHEMLNNI_02928 3.66e-274 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHEMLNNI_02929 9.51e-129 flaR - - F - - - topology modulation protein
HHEMLNNI_02930 4.11e-11 - - - S ko:K06327 - ko00000 Inner spore coat protein D
HHEMLNNI_02931 2.62e-111 ftnA 1.16.3.2 - P ko:K02217 - ko00000,ko01000 Iron-storage protein
HHEMLNNI_02932 9.74e-224 yueF - - S - - - transporter activity
HHEMLNNI_02933 0.0 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHEMLNNI_02934 4.87e-134 - - - S - - - Peptidase propeptide and YPEB domain
HHEMLNNI_02935 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HHEMLNNI_02936 1e-276 - - - G - - - COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HHEMLNNI_02937 6.22e-108 - - - G - - - Tripartite ATP-independent periplasmic transporters, DctQ component
HHEMLNNI_02938 5.97e-241 - - - G - - - Bacterial extracellular solute-binding protein, family 7
HHEMLNNI_02939 1.27e-224 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HHEMLNNI_02940 1.33e-181 - - - K - - - helix_turn_helix, mercury resistance
HHEMLNNI_02941 0.0 yvcC1 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HHEMLNNI_02942 3.25e-190 murR - - K - - - Transcriptional regulator
HHEMLNNI_02943 3.05e-235 pdxA 1.1.1.408, 1.1.1.409 - H ko:K22024 - ko00000,ko01000 Belongs to the PdxA family
HHEMLNNI_02944 4.99e-309 - 2.7.1.219, 2.7.1.220 - S ko:K22129 - ko00000,ko01000 Putative nucleotide-binding of sugar-metabolising enzyme
HHEMLNNI_02945 4.37e-218 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HHEMLNNI_02947 0.0 - - - K - - - Propionate catabolism activator
HHEMLNNI_02948 2.91e-200 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHEMLNNI_02949 3.64e-306 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_02950 1.34e-256 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
HHEMLNNI_02951 1.58e-239 purR15 - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
HHEMLNNI_02952 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HHEMLNNI_02953 1.47e-213 - - - GK - - - ROK family
HHEMLNNI_02954 3.26e-199 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_02955 3.47e-215 - - - P ko:K02026,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HHEMLNNI_02956 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_02957 1.6e-209 manA3 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Endoglucanase
HHEMLNNI_02958 1.34e-52 - - - S - - - Protein of unknown function (DUF2642)
HHEMLNNI_02960 4.72e-127 - - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HHEMLNNI_02961 5.57e-71 fdx5 - - C - - - 2Fe-2S iron-sulfur cluster binding domain
HHEMLNNI_02962 2.13e-28 - - - - - - - -
HHEMLNNI_02963 0.0 - - - KT - - - Transcriptional regulator
HHEMLNNI_02964 1.77e-280 adhB 1.1.1.1, 1.1.1.202 - C ko:K00001,ko:K00086 ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HHEMLNNI_02965 4.34e-298 - - - EG - - - COG2610 H gluconate symporter and related permeases
HHEMLNNI_02966 1.14e-224 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HHEMLNNI_02967 9.95e-267 - - - C ko:K19954 - ko00000,ko01000 alcohol dehydrogenase
HHEMLNNI_02968 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHEMLNNI_02969 0.0 - - - EG ko:K06295 - ko00000 Bacillus/Clostridium GerA spore germination protein
HHEMLNNI_02970 2.63e-90 - - - - - - - -
HHEMLNNI_02971 1.77e-116 ectA 2.3.1.178 - K ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 ko00000,ko00001,ko00002,ko01000 L-2,4-diaminobutyric acid acetyltransferase
HHEMLNNI_02972 3.32e-315 ectB 2.6.1.76 - E ko:K00836 ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHEMLNNI_02973 4.56e-99 ectC 4.2.1.108 - S ko:K06720 ko00260,ko01100,ko01120,map00260,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
HHEMLNNI_02974 0.0 - - - G ko:K02027,ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Glycerol-3-phosphate ABC transporter substrate-binding protein
HHEMLNNI_02975 9.88e-197 - - - G - - - Xylose isomerase-like TIM barrel
HHEMLNNI_02976 2.75e-211 - - - G ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HHEMLNNI_02977 2.4e-190 - - - P ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
HHEMLNNI_02978 1.56e-247 - 3.6.3.20 - P ko:K05816 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_02979 0.0 alkK - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHEMLNNI_02980 0.0 - 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HHEMLNNI_02981 4.73e-258 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HHEMLNNI_02982 6.08e-38 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HHEMLNNI_02984 1.11e-50 - - - S - - - Family of unknown function (DUF5344)
HHEMLNNI_02985 5.91e-301 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_02986 1.15e-58 - - - - - - - -
HHEMLNNI_02988 4.3e-187 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HHEMLNNI_02989 2.28e-249 yneE - - K - - - Arabinose-binding domain of AraC transcription regulator, N-term
HHEMLNNI_02990 1.47e-100 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HHEMLNNI_02991 5.99e-308 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHEMLNNI_02992 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HHEMLNNI_02993 4.35e-262 ugpC 3.6.3.20 - P ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_02994 5.95e-211 ugpA - - G ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HHEMLNNI_02995 5.39e-184 ugpE - - P ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Glycerol-3-phosphate ABC transporter permease
HHEMLNNI_02996 3.09e-307 ugpB - - G ko:K02027,ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Glycerol-3-phosphate ABC transporter substrate-binding protein
HHEMLNNI_02997 3.56e-183 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HHEMLNNI_02998 7.67e-273 - - - EGP ko:K08162 - ko00000,ko02000 Major Facilitator Superfamily
HHEMLNNI_02999 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_03000 2.94e-194 - - - G - - - Haloacid dehalogenase-like hydrolase
HHEMLNNI_03001 1.02e-120 - - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HHEMLNNI_03002 1.09e-225 - - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03003 1.06e-200 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HHEMLNNI_03004 3.96e-166 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HHEMLNNI_03005 9.42e-232 - - - G - - - Xylose isomerase-like TIM barrel
HHEMLNNI_03006 4.12e-254 - 1.1.1.361 - S ko:K18652 - ko00000,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_03007 4.08e-137 ykoP - - G - - - polysaccharide deacetylase
HHEMLNNI_03008 1.03e-264 - - - - - - - -
HHEMLNNI_03009 6.82e-183 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_03010 8.47e-202 - - - K - - - helix_turn_helix, arabinose operon control protein
HHEMLNNI_03011 5.5e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHEMLNNI_03012 5.18e-221 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HHEMLNNI_03013 0.0 - - - E - - - amino acid
HHEMLNNI_03014 3.99e-232 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_03015 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HHEMLNNI_03016 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HHEMLNNI_03017 1.21e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HHEMLNNI_03018 9.68e-291 - - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HHEMLNNI_03019 1.5e-193 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_03020 4.97e-294 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HHEMLNNI_03021 1.16e-284 - - - EM - - - Protein of unknown function (DUF993)
HHEMLNNI_03022 3.31e-199 - - - G - - - Xylose isomerase-like TIM barrel
HHEMLNNI_03023 2.53e-288 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HHEMLNNI_03024 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_03025 2.73e-264 - - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HHEMLNNI_03026 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_03027 2.04e-225 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03028 2.42e-200 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03029 2.9e-255 - - - I - - - Acyltransferase family
HHEMLNNI_03030 1.47e-301 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HHEMLNNI_03031 1.39e-152 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_03032 5.87e-202 - - - K - - - LysR substrate binding domain
HHEMLNNI_03033 8.03e-164 - - - S - - - L-2-amino-thiazoline-4-carboxylic acid hydrolase
HHEMLNNI_03035 0.0 yesW 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HHEMLNNI_03036 1.16e-304 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_03037 2.9e-189 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03038 2.52e-202 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03039 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HHEMLNNI_03040 1.37e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_03041 1.25e-204 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03042 4.49e-196 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03043 1.33e-140 - - - S - - - Protein of unknown function, DUF624
HHEMLNNI_03044 7.97e-222 M1-640 - - K - - - Transcriptional regulator
HHEMLNNI_03045 2.76e-215 rhaR1 - - K - - - AraC-like ligand binding domain
HHEMLNNI_03046 2.79e-181 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HHEMLNNI_03047 1.89e-275 egsA 1.1.1.261 - C ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HHEMLNNI_03048 2.15e-176 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HHEMLNNI_03049 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HHEMLNNI_03050 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HHEMLNNI_03051 5.62e-252 chvE - - G ko:K10546 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHEMLNNI_03052 0.0 araG 3.6.3.17 - G ko:K10548 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HHEMLNNI_03053 3.63e-253 araH - - G ko:K10544,ko:K10547 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HHEMLNNI_03054 0.0 melA7 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HHEMLNNI_03055 6.21e-63 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HHEMLNNI_03057 3.11e-106 - - - S - - - Putative small multi-drug export protein
HHEMLNNI_03058 4.73e-149 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HHEMLNNI_03059 1.06e-240 - - - KTV ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
HHEMLNNI_03060 4.09e-63 ykkD_1 - - P ko:K18925 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HHEMLNNI_03061 2.06e-78 ykkC_1 - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HHEMLNNI_03062 1.47e-130 yvdT_1 - - K - - - Transcriptional regulator
HHEMLNNI_03063 3.67e-310 - - - EGP - - - Major Facilitator Superfamily
HHEMLNNI_03064 2.48e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HHEMLNNI_03065 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHEMLNNI_03066 1.41e-199 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HHEMLNNI_03067 2.68e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HHEMLNNI_03068 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HHEMLNNI_03069 1.75e-225 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HHEMLNNI_03070 6.31e-252 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HHEMLNNI_03071 5.52e-208 iolJ 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HHEMLNNI_03072 4.95e-246 - 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HHEMLNNI_03073 0.0 - - - S ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHEMLNNI_03074 2.79e-135 - - - S - - - Protein of unknown function (DUF421)
HHEMLNNI_03075 5.4e-311 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 O-acetylhomoserine
HHEMLNNI_03077 1.2e-85 - - - S ko:K06940 - ko00000 Putative zinc- or iron-chelating domain
HHEMLNNI_03078 4.06e-181 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03079 6.7e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03080 0.0 - - - G ko:K02027,ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_03081 6.19e-209 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_03082 5.8e-248 - 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HHEMLNNI_03083 3.33e-242 - - - G - - - Bacterial extracellular solute-binding protein, family 7
HHEMLNNI_03084 6.56e-107 - - - G - - - Tripartite ATP-independent periplasmic transporters, DctQ component
HHEMLNNI_03085 4.36e-284 - - - G - - - Tripartite ATP-independent periplasmic transporter, DctM component
HHEMLNNI_03086 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HHEMLNNI_03087 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HHEMLNNI_03088 0.0 - - - K ko:K03491 - ko00000,ko03000 transcriptional regulator, MtlR
HHEMLNNI_03089 3.06e-204 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HHEMLNNI_03090 2.14e-100 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHEMLNNI_03091 6.25e-63 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HHEMLNNI_03092 7.44e-238 fruA2 - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
HHEMLNNI_03093 1.72e-121 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HHEMLNNI_03095 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHEMLNNI_03096 1.2e-203 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HHEMLNNI_03097 5.76e-134 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HHEMLNNI_03098 0.0 - - - KT - - - Transcriptional regulator
HHEMLNNI_03099 3.5e-306 - - - E - - - Acyclic terpene utilisation family protein AtuA
HHEMLNNI_03100 1.27e-70 - - - - - - - -
HHEMLNNI_03101 4.1e-291 - - - C ko:K03300 - ko00000 Citrate transporter
HHEMLNNI_03102 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HHEMLNNI_03103 5.55e-304 - - - V - - - MatE
HHEMLNNI_03104 2.3e-129 - - - S - - - Tetratricopeptide repeat
HHEMLNNI_03105 4.27e-89 - - - F - - - NUDIX domain
HHEMLNNI_03106 7.29e-137 - - - - - - - -
HHEMLNNI_03107 1.24e-170 - - - - - - - -
HHEMLNNI_03108 0.0 - - - - - - - -
HHEMLNNI_03109 1.22e-70 - - - - - - - -
HHEMLNNI_03110 1.08e-244 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 mannonate dehydratase activity
HHEMLNNI_03111 3.31e-239 - - - S - - - Tripartite tricarboxylate transporter family receptor
HHEMLNNI_03112 0.0 - - - S ko:K07793 ko02020,map02020 ko00000,ko00001,ko02000 Tripartite tricarboxylate transporter TctA family
HHEMLNNI_03113 8e-108 - - - S - - - Tripartite tricarboxylate transporter TctB family
HHEMLNNI_03114 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHEMLNNI_03115 4.78e-220 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HHEMLNNI_03116 6.32e-158 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HHEMLNNI_03117 8.43e-58 - - - UW - - - Collagen triple helix repeat (20 copies)
HHEMLNNI_03118 7.33e-272 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HHEMLNNI_03119 7.98e-156 - - - K ko:K05799 - ko00000,ko03000 FCD
HHEMLNNI_03120 3.22e-255 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HHEMLNNI_03121 6.88e-80 - - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
HHEMLNNI_03123 2.45e-95 - - - K - - - Transcriptional regulator
HHEMLNNI_03124 3.28e-182 - 3.4.16.4 - V ko:K01286 - ko00000,ko01000 Beta-lactamase
HHEMLNNI_03125 2.6e-170 yybG - - S - - - Pentapeptide repeat-containing protein
HHEMLNNI_03126 3.7e-60 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_03127 1.37e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHEMLNNI_03128 5.36e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_03129 0.0 gmuD 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HHEMLNNI_03130 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HHEMLNNI_03131 1.61e-117 - - - K - - - Bacterial transcription activator, effector binding domain
HHEMLNNI_03132 4.78e-110 - - - - - - - -
HHEMLNNI_03133 6.66e-24 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HHEMLNNI_03134 1.03e-126 - - - M - - - 3D domain
HHEMLNNI_03135 4.61e-293 - - - JM - - - Bacterial transferase hexapeptide (six repeats)
HHEMLNNI_03136 1.62e-167 frlR3 - - K ko:K03710 - ko00000,ko03000 transcriptional
HHEMLNNI_03137 3.29e-181 - - - S - - - carbohydrate derivative metabolic process
HHEMLNNI_03139 0.0 - - - I - - - radical SAM domain protein
HHEMLNNI_03140 0.0 - 1.3.98.3 - H ko:K02495 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of porphyrin-containing compound
HHEMLNNI_03142 1.68e-177 yafE - - Q - - - methyltransferase
HHEMLNNI_03144 6.9e-116 - - - S - - - Uncharacterised protein family UPF0066
HHEMLNNI_03145 1.2e-283 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HHEMLNNI_03146 7.95e-133 - - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHEMLNNI_03147 7.62e-219 - 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
HHEMLNNI_03148 5.81e-163 - - - M - - - Glycosyl transferases group 1
HHEMLNNI_03149 4.19e-130 - - - - - - - -
HHEMLNNI_03150 4.55e-130 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 transferase activity, transferring glycosyl groups
HHEMLNNI_03151 9.09e-152 - - - M - - - transferase activity, transferring glycosyl groups
HHEMLNNI_03152 4.23e-146 - - - M - - - Glycosyl transferase family 2
HHEMLNNI_03153 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHEMLNNI_03154 3.19e-35 ybbJ - - K - - - acetyltransferase
HHEMLNNI_03155 0.0 - - - M - - - Glycosyltransferase like family 2
HHEMLNNI_03156 6.43e-55 - - - S - - - Protein of unknown function (DUF2642)
HHEMLNNI_03157 1.13e-36 - - - - - - - -
HHEMLNNI_03158 3.63e-309 VCP - - O - - - AAA domain (dynein-related subfamily)
HHEMLNNI_03159 6.07e-144 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HHEMLNNI_03160 2.73e-161 - - - K - - - helix_turn_helix isocitrate lyase regulation
HHEMLNNI_03161 1.38e-203 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HHEMLNNI_03162 5.39e-133 - 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
HHEMLNNI_03163 1.72e-290 dgoD 4.2.1.6 - M ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HHEMLNNI_03164 3.46e-205 - - - S - - - Metallo-beta-lactamase superfamily
HHEMLNNI_03165 1.39e-115 - - - S - - - Predicted membrane protein (DUF2243)
HHEMLNNI_03166 3.6e-161 - - - S ko:K02351 - ko00000 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
HHEMLNNI_03167 3.8e-309 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HHEMLNNI_03168 1.51e-163 - - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_03169 9.21e-244 - - - K - - - DJ-1/PfpI family
HHEMLNNI_03170 1.9e-145 - - - S - - - Predicted membrane protein (DUF2306)
HHEMLNNI_03171 1.26e-265 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HHEMLNNI_03172 2.25e-100 - - - S - - - VanZ like family
HHEMLNNI_03173 1.2e-144 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HHEMLNNI_03174 1.52e-119 - - - K - - - Acetyltransferase (GNAT) family
HHEMLNNI_03175 2.26e-168 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HHEMLNNI_03176 0.0 - - - V - - - SNF2 family N-terminal domain
HHEMLNNI_03179 0.0 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_03180 2.83e-144 - - - - - - - -
HHEMLNNI_03181 1.6e-125 - - - - - - - -
HHEMLNNI_03182 2.72e-194 - - - - - - - -
HHEMLNNI_03183 0.0 - - - E - - - Sodium:solute symporter family
HHEMLNNI_03184 8.92e-29 - - - - - - - -
HHEMLNNI_03185 3.24e-292 bbsF_2 2.8.3.16 - C ko:K07749 - ko00000,ko01000 acyl-CoA transferases carnitine dehydratase
HHEMLNNI_03186 3.56e-152 - - - K - - - FCD domain
HHEMLNNI_03187 9.37e-212 - 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HHEMLNNI_03188 5.17e-273 - - - G - - - Transmembrane secretion effector
HHEMLNNI_03190 3.69e-131 ybbH - - K - - - RpiR family transcriptional regulator
HHEMLNNI_03191 4.81e-228 - - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HHEMLNNI_03192 8.25e-161 garR 1.1.1.60 - I ko:K00042 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HHEMLNNI_03193 3.5e-236 - - - S - - - Putative nucleotide-binding of sugar-metabolising enzyme
HHEMLNNI_03194 3.59e-284 hmrA - - S ko:K12941,ko:K21613 - ko00000,ko01000,ko01002 amidohydrolase
HHEMLNNI_03195 6.67e-202 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HHEMLNNI_03196 3.91e-145 - - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HHEMLNNI_03197 4.2e-241 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHEMLNNI_03198 3.06e-213 - - - K - - - helix_turn_helix, arabinose operon control protein
HHEMLNNI_03200 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HHEMLNNI_03201 0.0 aguA 3.2.1.139 - G ko:K01235 - ko00000,ko01000 Belongs to the glycosyl hydrolase 67 family
HHEMLNNI_03202 4.62e-225 - - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03203 5.44e-197 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HHEMLNNI_03204 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_03205 5.36e-157 - - - S - - - Protein of unknown function, DUF624
HHEMLNNI_03206 6.33e-254 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
HHEMLNNI_03208 2.59e-146 - - - L - - - DNA restriction-modification system
HHEMLNNI_03209 6.21e-43 - - - D - - - nuclear chromosome segregation
HHEMLNNI_03211 3.56e-280 hutI - - Q - - - COG1228 Imidazolonepropionase and related amidohydrolases
HHEMLNNI_03212 5.3e-264 - - - Q - - - COG1228 Imidazolonepropionase and related amidohydrolases
HHEMLNNI_03213 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HHEMLNNI_03214 4.39e-219 - - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_03215 6.57e-197 - - - EP ko:K02034,ko:K13891 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_03216 7.86e-242 - - - P ko:K02031,ko:K16202 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_03217 1.5e-242 - - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_03218 3.38e-225 - - - S - - - Protein of unknown function (DUF1177)
HHEMLNNI_03219 4.76e-308 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HHEMLNNI_03220 5.63e-176 - - - K - - - Transcriptional regulator
HHEMLNNI_03221 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HHEMLNNI_03222 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HHEMLNNI_03223 5.24e-259 mro 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
HHEMLNNI_03224 3.43e-281 xylR5 - - GK - - - ROK family
HHEMLNNI_03225 5.09e-161 - - - S ko:K09992 - ko00000 Trehalose utilisation
HHEMLNNI_03226 7.22e-283 yrbE - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_03227 0.0 - - - KT ko:K09684 - ko00000,ko03000 PucR C-terminal helix-turn-helix domain
HHEMLNNI_03228 9.27e-143 - - - E - - - Asp/Glu/Hydantoin racemase
HHEMLNNI_03229 0.0 - - - S - - - OPT oligopeptide transporter protein
HHEMLNNI_03230 9.57e-244 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
HHEMLNNI_03231 1.04e-217 - - - S - - - Protein of unknown function (DUF1177)
HHEMLNNI_03232 9.74e-146 - - - E ko:K14591 - ko00000 AroM protein
HHEMLNNI_03233 1.13e-223 - - - E - - - Thermophilic metalloprotease (M29)
HHEMLNNI_03234 4.58e-222 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HHEMLNNI_03235 2.4e-42 - 5.3.2.6 - S ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Tautomerase enzyme
HHEMLNNI_03236 4.29e-275 chrA - - P ko:K07240 - ko00000,ko02000 chromate transporter, chromate ion transporter
HHEMLNNI_03238 1.2e-59 M1-594 - - S - - - Thiamine-binding protein
HHEMLNNI_03239 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHEMLNNI_03240 1.19e-314 - - - - - - - -
HHEMLNNI_03242 5.07e-299 gntT - - EG - - - gluconate transmembrane transporter activity
HHEMLNNI_03243 2.98e-216 - 2.7.1.196, 2.7.1.205 - K ko:K02760,ko:K20480 ko00500,ko02024,ko02060,map00500,map02024,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 sequence-specific DNA binding
HHEMLNNI_03244 6.94e-160 yflK - - S - - - protein conserved in bacteria
HHEMLNNI_03245 4.12e-104 - - - - - - - -
HHEMLNNI_03246 4.28e-09 - - - S - - - Uncharacterized small protein (DUF2292)
HHEMLNNI_03247 6.32e-122 ssuE 1.5.1.38, 1.5.1.45 - S ko:K00299,ko:K16902 ko00380,ko00740,ko00920,ko01100,map00380,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
HHEMLNNI_03248 2.22e-231 - - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHEMLNNI_03249 7.9e-269 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HHEMLNNI_03250 3.67e-178 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHEMLNNI_03251 3.24e-168 ssuB - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HHEMLNNI_03253 1.4e-35 - - - - - - - -
HHEMLNNI_03255 7.8e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HHEMLNNI_03256 1.75e-278 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HHEMLNNI_03257 6.88e-237 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HHEMLNNI_03258 1.03e-144 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HHEMLNNI_03259 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HHEMLNNI_03260 1.19e-185 cbiX 4.99.1.3 - C ko:K03795 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 CbiX
HHEMLNNI_03261 8.66e-141 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HHEMLNNI_03262 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HHEMLNNI_03263 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HHEMLNNI_03264 1.56e-22 - - - - - - - -
HHEMLNNI_03265 1.25e-204 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HHEMLNNI_03266 1.47e-79 - - - K - - - GntR family transcriptional regulator
HHEMLNNI_03267 1.1e-278 yraM - - S - - - PrpF protein
HHEMLNNI_03268 9.21e-89 - - - S - - - Tripartite tricarboxylate transporter TctB family
HHEMLNNI_03269 0.0 - - - S - - - Tripartite tricarboxylate transporter TctA family
HHEMLNNI_03270 2.11e-271 - - - S - - - Tripartite tricarboxylate transporter family receptor
HHEMLNNI_03271 3.92e-215 yraN - - K - - - Transcriptional regulator
HHEMLNNI_03272 1.89e-254 icd 1.1.1.41, 1.1.1.42, 1.1.1.85 - CE ko:K00030,ko:K00031,ko:K00052 ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
HHEMLNNI_03273 0.0 - - - C ko:K13796 - ko00000 COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
HHEMLNNI_03274 7.07e-247 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HHEMLNNI_03275 1.13e-276 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HHEMLNNI_03276 4.34e-199 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HHEMLNNI_03277 1.4e-75 - - - K - - - FCD
HHEMLNNI_03278 6.1e-197 - - - P ko:K14445 - ko00000,ko02000 Sodium:sulfate symporter transmembrane region
HHEMLNNI_03279 4.44e-195 - 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HHEMLNNI_03280 1.86e-134 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HHEMLNNI_03281 2.38e-133 - - - K - - - Bacterial regulatory proteins, tetR family
HHEMLNNI_03282 1.53e-240 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
HHEMLNNI_03283 7.21e-213 - - - P - - - Arsenic resistance protein
HHEMLNNI_03284 1.54e-124 - - - - - - - -
HHEMLNNI_03285 2.59e-169 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HHEMLNNI_03286 3.48e-59 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_03287 7.12e-69 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_03288 4.12e-310 ywbA - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHEMLNNI_03289 0.0 - 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHEMLNNI_03290 2.93e-178 celCD 2.7.1.196, 2.7.1.205, 3.5.1.105 - G ko:K02759,ko:K03478 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
HHEMLNNI_03291 6.12e-179 ybgA - - K ko:K03710 - ko00000,ko03000 UTRA
HHEMLNNI_03292 0.0 chiA 3.2.1.14 GH18 G ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Glycoside Hydrolase Family 18
HHEMLNNI_03293 1.18e-51 - - - S - - - Family of unknown function (DUF5391)
HHEMLNNI_03294 2.48e-72 yxeA - - S - - - Protein of unknown function (DUF1093)
HHEMLNNI_03295 1.13e-290 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HHEMLNNI_03296 1.03e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HHEMLNNI_03297 0.0 kynU 3.7.1.3 - E ko:K01556 ko00380,ko01100,map00380,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
HHEMLNNI_03298 1.4e-152 kynB 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HHEMLNNI_03299 2.82e-202 kynA 1.13.11.11 - E ko:K00453 ko00380,ko01100,map00380,map01100 ko00000,ko00001,ko00002,ko01000 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
HHEMLNNI_03300 2.93e-89 - - - S - - - Domain of unknown function (DUF4352)
HHEMLNNI_03301 2.87e-269 - - - E ko:K06296 - ko00000,ko02000 Spore germination protein
HHEMLNNI_03303 4.55e-285 gerAC1 - - S ko:K06297 - ko00000 spore germination
HHEMLNNI_03304 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
HHEMLNNI_03305 5e-174 - - - K - - - DeoR C terminal sensor domain
HHEMLNNI_03306 8.5e-303 - 2.7.1.219, 2.7.1.220 - S ko:K22129 - ko00000,ko01000 Putative nucleotide-binding of sugar-metabolising enzyme
HHEMLNNI_03307 1.03e-238 pdxA 1.1.1.408, 1.1.1.409 - H ko:K22024 - ko00000,ko01000 Belongs to the PdxA family
HHEMLNNI_03308 3.27e-284 gntP - - EG ko:K03299 - ko00000,ko02000 GntP family permease
HHEMLNNI_03312 1.03e-34 - - - E - - - Aminotransferase
HHEMLNNI_03313 6.38e-83 - - - EGP - - - Transmembrane secretion effector
HHEMLNNI_03314 6.65e-196 araQ5 - - P ko:K10190,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
HHEMLNNI_03315 1.84e-209 cebF - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
HHEMLNNI_03316 3.88e-289 lacE3 - - G ko:K10240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 1
HHEMLNNI_03318 5.01e-293 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HHEMLNNI_03319 3.14e-167 - - - T - - - Response regulator receiver domain
HHEMLNNI_03320 0.0 - 2.7.13.3 - T ko:K02476,ko:K11614,ko:K11637 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HHEMLNNI_03321 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HHEMLNNI_03322 8.74e-161 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HHEMLNNI_03323 7.63e-249 - - - G - - - Acyltransferase family
HHEMLNNI_03324 1.99e-207 - - - P - - - YhfZ C-terminal domain
HHEMLNNI_03325 5.73e-75 - - - S - - - PRD domain
HHEMLNNI_03326 1.98e-76 - - - S - - - Protein of unknown function DUF2620
HHEMLNNI_03327 3.44e-283 - - - S - - - Protein of unknown function
HHEMLNNI_03328 6.07e-223 php - - S ko:K07048 - ko00000 Phosphotriesterase family
HHEMLNNI_03329 3.72e-262 - - - E - - - Cys/Met metabolism PLP-dependent enzyme
HHEMLNNI_03330 3.3e-281 - - - E - - - Alanine racemase, N-terminal domain
HHEMLNNI_03331 1.37e-290 - - - G - - - Metalloenzyme superfamily
HHEMLNNI_03333 0.0 - - - O - - - DnaJ molecular chaperone homology domain
HHEMLNNI_03334 0.0 hscC - - O ko:K04045 - ko00000,ko03110 Hsp70 protein
HHEMLNNI_03335 4.65e-182 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HHEMLNNI_03336 2.79e-195 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HHEMLNNI_03337 7.14e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HHEMLNNI_03338 6.07e-223 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_03339 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_03340 9.01e-198 M1-465 - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03341 3.86e-204 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03342 3.62e-65 esxA - - S - - - Belongs to the WXG100 family
HHEMLNNI_03343 7.61e-52 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HHEMLNNI_03344 5.39e-278 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HHEMLNNI_03345 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HHEMLNNI_03346 0.0 yueB - - S - - - domain protein
HHEMLNNI_03347 2.51e-93 - - - S - - - Family of unknown function (DUF5383)
HHEMLNNI_03348 4.22e-60 - - - - - - - -
HHEMLNNI_03349 4.05e-64 - - - - - - - -
HHEMLNNI_03350 3.83e-104 - - - - - - - -
HHEMLNNI_03351 1.39e-186 - - - S - - - nuclease activity
HHEMLNNI_03359 5.09e-12 - - - S - - - nuclease activity
HHEMLNNI_03361 6.99e-115 - - - - - - - -
HHEMLNNI_03365 3.24e-223 - - - G - - - Glycoside hydrolase family 16
HHEMLNNI_03371 1.01e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 COG1136 ABC-type antimicrobial peptide transport system, ATPase component
HHEMLNNI_03372 0.0 - - - Q ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HHEMLNNI_03373 5.98e-116 - - - K - - - Transcriptional regulator PadR-like family
HHEMLNNI_03374 4e-105 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HHEMLNNI_03375 3.12e-181 - - - K - - - Helix-turn-helix domain, rpiR family
HHEMLNNI_03376 8.63e-154 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HHEMLNNI_03377 0.0 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_03378 9.42e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HHEMLNNI_03379 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHEMLNNI_03380 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
HHEMLNNI_03381 1.99e-136 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
HHEMLNNI_03382 9.42e-163 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 nitrate reductase, gamma subunit
HHEMLNNI_03383 2.06e-108 nreA - - T ko:K10851 ko02020,map02020 ko00000,ko00001 phosphoenolpyruvate-protein phosphotransferase activity
HHEMLNNI_03384 6.61e-256 nreB 2.7.13.3 - T ko:K07683,ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HHEMLNNI_03385 8.71e-148 nreC - - T ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHEMLNNI_03386 0.0 narK - - P ko:K02575,ko:K10850 ko00910,ko02020,map00910,map02020 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HHEMLNNI_03387 1.22e-166 - - - S - - - YwiC-like protein
HHEMLNNI_03388 1.63e-189 yjqC - - P ko:K07217 - ko00000 Catalase
HHEMLNNI_03389 2.22e-138 ycgF - - E - - - Lysine exporter protein LysE YggA
HHEMLNNI_03390 8.65e-310 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HHEMLNNI_03391 9.09e-149 yhcQ - - M - - - Spore coat protein
HHEMLNNI_03392 3.42e-06 - - - S - - - Sporulation inhibitor A
HHEMLNNI_03393 2.84e-213 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
HHEMLNNI_03394 1.17e-219 eutB 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HHEMLNNI_03395 5.29e-268 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HHEMLNNI_03396 1.02e-146 - - - S - - - HTH domain
HHEMLNNI_03397 3.31e-239 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Arginase family
HHEMLNNI_03398 1.44e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
HHEMLNNI_03399 6.67e-259 - - - T - - - Histidine kinase
HHEMLNNI_03400 1.85e-211 - 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HHEMLNNI_03401 2.59e-160 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HHEMLNNI_03402 6.46e-150 ydfE - - S - - - Flavin reductase like domain
HHEMLNNI_03403 2.73e-149 - - - S - - - ABC-2 family transporter protein
HHEMLNNI_03404 3.08e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_03405 6.39e-212 ycbM - - T - - - Histidine kinase
HHEMLNNI_03406 1.39e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHEMLNNI_03407 8.46e-301 hisD 1.1.1.23, 1.1.1.308 - E ko:K00013,ko:K15509 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHEMLNNI_03408 2.62e-217 - - - K - - - helix_turn _helix lactose operon repressor
HHEMLNNI_03409 8.7e-296 - - - EG - - - COG2610 H gluconate symporter and related permeases
HHEMLNNI_03410 0.0 - - - M - - - Domain of unknown function DUF11
HHEMLNNI_03411 1.78e-115 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HHEMLNNI_03412 2.92e-42 - - - S - - - Sporulation inhibitor A
HHEMLNNI_03413 5.31e-188 - - AA10,CBM73 D ko:K03933 - ko00000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
HHEMLNNI_03414 5.87e-182 - 1.1.1.140 - C ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HHEMLNNI_03415 7.15e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HHEMLNNI_03416 4.5e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol sorbitol-specific transporter subunit IIB
HHEMLNNI_03417 2.27e-128 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HHEMLNNI_03418 1.72e-99 srlR - - K - - - Glucitol operon activator
HHEMLNNI_03419 4.42e-222 - - - K - - - COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HHEMLNNI_03420 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HHEMLNNI_03421 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HHEMLNNI_03422 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_03423 1e-156 yteU - - S - - - Integral membrane protein
HHEMLNNI_03424 2.34e-102 - - - G - - - carbohydrate transport
HHEMLNNI_03425 1.39e-283 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HHEMLNNI_03426 0.0 - 3.2.1.37, 3.2.1.55 GH43,GH51 G ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HHEMLNNI_03427 1.41e-214 - - - E - - - Abhydrolase family
HHEMLNNI_03428 5.67e-200 ytcP3 - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03429 2.8e-230 - - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HHEMLNNI_03430 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHEMLNNI_03431 0.0 - - - K - - - Transcriptional regulator
HHEMLNNI_03432 3.6e-208 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_03433 6.88e-259 - 4.2.2.2 - M ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectic acid lyase
HHEMLNNI_03434 2.33e-140 - - - J - - - Acetyltransferase (GNAT) domain
HHEMLNNI_03435 8.66e-169 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HHEMLNNI_03436 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
HHEMLNNI_03437 0.0 lplA3 - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_03438 1.13e-217 lplC1 - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03439 4.46e-228 - - - P ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03440 0.0 - - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HHEMLNNI_03441 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_03442 0.0 yicI 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
HHEMLNNI_03443 4.02e-265 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HHEMLNNI_03444 1.41e-240 nagC_1 - - GK - - - ROK family
HHEMLNNI_03445 0.0 M1-1044 - - S - - - Belongs to the UPF0061 (SELO) family
HHEMLNNI_03446 4.31e-278 - 4.2.1.7 - G ko:K16850 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 D-galactarate dehydratase / Altronate hydrolase, C terminus
HHEMLNNI_03447 1.37e-64 - 4.2.1.7 - G ko:K16849 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 SAF
HHEMLNNI_03448 8.2e-273 - - - G - - - Tripartite ATP-independent periplasmic transporter, DctM component
HHEMLNNI_03449 1.35e-118 - - - G - - - Tripartite ATP-independent periplasmic transporters, DctQ component
HHEMLNNI_03450 9.3e-249 - - - G - - - Bacterial extracellular solute-binding protein, family 7
HHEMLNNI_03451 3.09e-209 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_03452 1.12e-211 - - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HHEMLNNI_03453 8.44e-178 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HHEMLNNI_03454 5.77e-209 - - - S - - - Alpha beta hydrolase
HHEMLNNI_03456 1.05e-224 yjiA - - S - - - Cobalamin biosynthesis protein CobW
HHEMLNNI_03457 1e-246 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HHEMLNNI_03458 0.0 psaA3 - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Zinc-uptake complex component A periplasmic
HHEMLNNI_03459 1.98e-172 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HHEMLNNI_03460 5.66e-170 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HHEMLNNI_03461 7.64e-94 - 2.3.1.82 - J ko:K00663 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HHEMLNNI_03462 0.0 - - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHEMLNNI_03463 7.02e-213 - 4.1.2.28, 4.3.3.7 - EM ko:K01714,ko:K22397 ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
HHEMLNNI_03464 3.75e-209 - 4.2.1.141 - S ko:K14259 ko00040,map00040 ko00000,ko00001,ko01000 Fumarylacetoacetate (FAA) hydrolase family
HHEMLNNI_03465 1.23e-182 - - - K ko:K19333 - ko00000,ko03000 helix_turn_helix isocitrate lyase regulation
HHEMLNNI_03466 0.0 - 4.2.1.82 - EG ko:K22396 ko00040,map00040 ko00000,ko00001,ko01000 Dehydratase family
HHEMLNNI_03467 6.67e-315 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HHEMLNNI_03468 3.12e-95 - - - - - - - -
HHEMLNNI_03469 2.03e-88 - - - S - - - Glycosyl transferases group 1
HHEMLNNI_03470 5.49e-58 B4168_4126 - - L ko:K07493 - ko00000 Transposase, Mutator family
HHEMLNNI_03472 3.93e-116 ccpB - - K - - - Transcriptional regulator
HHEMLNNI_03473 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHEMLNNI_03474 2.22e-284 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system ascorbate-specific transporter subunit IIC
HHEMLNNI_03475 8.46e-58 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG3414 Phosphotransferase system, galactitol-specific IIB component
HHEMLNNI_03476 0.0 - 2.7.1.194 - GKT ko:K02821,ko:K03483 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 COG3711 Transcriptional antiterminator
HHEMLNNI_03477 5.05e-131 - - - - - - - -
HHEMLNNI_03478 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHEMLNNI_03479 1.2e-105 ykuN - - C ko:K03839 - ko00000 Flavodoxin
HHEMLNNI_03480 1.43e-219 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHEMLNNI_03481 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHEMLNNI_03482 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHEMLNNI_03483 3.39e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHEMLNNI_03484 5.2e-118 yizA - - S - - - DinB family
HHEMLNNI_03485 1.44e-229 - - - - - - - -
HHEMLNNI_03487 2.6e-209 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HHEMLNNI_03488 1.3e-242 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HHEMLNNI_03489 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_03490 2.24e-261 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HHEMLNNI_03491 8.79e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HHEMLNNI_03492 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHEMLNNI_03493 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HHEMLNNI_03494 9.55e-167 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HHEMLNNI_03495 1.76e-195 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HHEMLNNI_03496 2.74e-221 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_03497 2.44e-226 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHEMLNNI_03499 5.02e-33 mepA - - V - - - MATE efflux family protein
HHEMLNNI_03500 1.87e-215 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HHEMLNNI_03501 0.0 acyII 3.5.1.11 - S ko:K01434 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000,ko01002 Penicillin amidase
HHEMLNNI_03502 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HHEMLNNI_03503 1.55e-66 yerC - - S - - - protein conserved in bacteria
HHEMLNNI_03504 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HHEMLNNI_03505 3.82e-255 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HHEMLNNI_03507 1.76e-208 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HHEMLNNI_03508 6.84e-190 gbuB - - P ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HHEMLNNI_03509 7.21e-281 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HHEMLNNI_03510 2.22e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HHEMLNNI_03511 3.59e-21 - - - - - - - -
HHEMLNNI_03512 2.62e-88 - - - - - - - -
HHEMLNNI_03513 1.25e-68 - - - - - - - -
HHEMLNNI_03514 1.98e-32 - - - S - - - Domain of unknown function (DUF4926)
HHEMLNNI_03515 6.99e-65 - - - - - - - -
HHEMLNNI_03516 2.16e-66 - - - - - - - -
HHEMLNNI_03517 3.57e-97 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_03518 1.11e-65 - - - - - - - -
HHEMLNNI_03519 5.67e-92 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_03520 3.41e-112 - - - S - - - SMI1-KNR4 cell-wall
HHEMLNNI_03521 5.84e-51 - - - S - - - A nuclease of the HNH/ENDO VII superfamily with conserved WHH
HHEMLNNI_03522 1.03e-76 - - - - - - - -
HHEMLNNI_03523 7.73e-300 - - - S - - - LXG domain of WXG superfamily
HHEMLNNI_03524 2.24e-50 - - - S - - - Family of unknown function (DUF5344)
HHEMLNNI_03525 1.36e-42 - - - S - - - Domain of unknown function (DUF5082)
HHEMLNNI_03527 1.57e-239 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HHEMLNNI_03528 7.48e-280 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HHEMLNNI_03529 4.96e-219 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HHEMLNNI_03530 3.54e-140 - - - KT - - - LuxR family transcriptional regulator
HHEMLNNI_03531 2.17e-213 - - - T - - - Signal transduction histidine kinase
HHEMLNNI_03532 1.12e-113 ttr - - K - - - GCN5 family acetyltransferase
HHEMLNNI_03533 2.33e-195 fhuD9 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HHEMLNNI_03534 1.61e-175 - 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_03535 2.91e-296 gntT - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HHEMLNNI_03536 1.62e-254 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HHEMLNNI_03537 1.68e-176 - 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_03538 1.11e-240 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HHEMLNNI_03539 9.85e-261 - 3.4.17.11 - E ko:K01295 - ko00000,ko01000,ko01002 Peptidase dimerisation domain
HHEMLNNI_03540 3.75e-303 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HHEMLNNI_03541 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HHEMLNNI_03542 1.21e-130 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHEMLNNI_03543 2.48e-253 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HHEMLNNI_03544 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHEMLNNI_03545 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHEMLNNI_03546 6.66e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHEMLNNI_03547 5.87e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHEMLNNI_03548 1.13e-164 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HHEMLNNI_03549 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHEMLNNI_03550 2.02e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHEMLNNI_03551 3.35e-106 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHEMLNNI_03552 7.64e-166 - - - S - - - CAAX protease self-immunity
HHEMLNNI_03553 1.62e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HHEMLNNI_03554 1.71e-156 - - - S - - - PFAM AIG2 family protein
HHEMLNNI_03555 1.66e-144 - - - - - - - -
HHEMLNNI_03556 8.23e-89 - - - S - - - Calcium/calmodulin dependent protein kinase II association domain
HHEMLNNI_03557 4.15e-42 yebG - - S - - - NETI protein
HHEMLNNI_03559 0.0 - - - S ko:K07793 ko02020,map02020 ko00000,ko00001,ko02000 Tripartite tricarboxylate transporter TctA family
HHEMLNNI_03560 1.2e-96 - - - S ko:K07794 ko02020,map02020 ko00000,ko00001,ko02000 Tripartite tricarboxylate transporter TctB family
HHEMLNNI_03561 1.72e-244 - - - S ko:K07795 ko02020,map02020 ko00000,ko00001,ko02000 Tripartite tricarboxylate transporter family receptor
HHEMLNNI_03562 9.4e-156 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HHEMLNNI_03563 0.0 - 2.7.13.3 - T ko:K02476,ko:K11614,ko:K11637 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HHEMLNNI_03564 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HHEMLNNI_03565 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HHEMLNNI_03566 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HHEMLNNI_03567 1.46e-16 - - - L ko:K07496 - ko00000 Transposase
HHEMLNNI_03569 3.86e-299 - - - G - - - Major facilitator Superfamily
HHEMLNNI_03572 2.2e-123 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HHEMLNNI_03573 9.93e-266 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HHEMLNNI_03574 3.78e-169 mta - - K - - - transcriptional
HHEMLNNI_03575 1.92e-152 - - - J - - - Acetyltransferase (GNAT) domain
HHEMLNNI_03576 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HHEMLNNI_03577 2.44e-207 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HHEMLNNI_03578 5.41e-173 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_03579 1.18e-172 - - - K - - - DeoR C terminal sensor domain
HHEMLNNI_03580 5.61e-115 - - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HHEMLNNI_03581 6.75e-138 ywrB - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HHEMLNNI_03582 2.01e-206 mqnD - - S ko:K11785 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HHEMLNNI_03583 6.77e-145 mqnB 3.2.2.26 - F ko:K11783 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HHEMLNNI_03584 0.0 lipA1 - - S - - - acetyltransferases and hydrolases with the alpha beta hydrolase fold
HHEMLNNI_03585 0.0 - - - K ko:K02538 - ko00000,ko03000 transcriptional antiterminator
HHEMLNNI_03586 1.93e-137 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HHEMLNNI_03587 0.0 - - - M - - - UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HHEMLNNI_03588 3.82e-214 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
HHEMLNNI_03589 1.03e-202 - - - E ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Substrate binding domain of ABC-type glycine betaine transport system
HHEMLNNI_03590 3.79e-131 - - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HHEMLNNI_03591 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HHEMLNNI_03592 4.08e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HHEMLNNI_03593 1.93e-177 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HHEMLNNI_03594 1.45e-162 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HHEMLNNI_03595 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HHEMLNNI_03596 2.93e-176 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HHEMLNNI_03597 0.0 - - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HHEMLNNI_03598 2.91e-27 - - - - - - - -
HHEMLNNI_03599 2.11e-292 cypA - - C ko:K15468 - ko00000,ko01008 Cytochrome P450
HHEMLNNI_03600 0.0 abgT_2 - - H ko:K12942 - ko00000 AbgT putative transporter family
HHEMLNNI_03601 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HHEMLNNI_03602 2.21e-133 - - - Q - - - Isochorismatase family
HHEMLNNI_03603 1.7e-101 ygaO - - - - - - -
HHEMLNNI_03604 4.52e-37 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_03605 0.0 - 3.1.3.5, 3.6.1.45 - F ko:K01081,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HHEMLNNI_03607 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HHEMLNNI_03608 0.0 - - - KT - - - Transcriptional regulator
HHEMLNNI_03609 3.12e-220 - - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HHEMLNNI_03610 3.34e-192 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HHEMLNNI_03611 2.96e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHEMLNNI_03612 0.0 - - - S - - - proteins of the AP superfamily
HHEMLNNI_03614 7.26e-286 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HHEMLNNI_03615 3.99e-92 - - - - - - - -
HHEMLNNI_03616 6.13e-232 - - - S - - - Phosphotransferase enzyme family
HHEMLNNI_03617 8.69e-278 - - - G - - - Transmembrane secretion effector
HHEMLNNI_03618 3.49e-32 - - - S - - - YfhD-like protein
HHEMLNNI_03619 1.68e-85 - 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HHEMLNNI_03620 2.72e-141 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HHEMLNNI_03621 1.18e-225 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863,ko:K05878 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dihydroxyacetone kinase DhaK, subunit
HHEMLNNI_03622 7.41e-110 M1-431 - - S - - - Protein of unknown function (DUF1706)
HHEMLNNI_03623 7.76e-98 rmaD - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HHEMLNNI_03624 1.98e-261 yvmA - - EGP - - - Major Facilitator Superfamily
HHEMLNNI_03625 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHEMLNNI_03626 3.16e-296 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system ascorbate-specific transporter subunit IIC
HHEMLNNI_03627 2.17e-57 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HHEMLNNI_03628 3.55e-299 - 2.7.1.194 - GKT ko:K02821,ko:K03483 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 COG3711 Transcriptional antiterminator
HHEMLNNI_03629 4.51e-147 - 2.7.1.194 - GKT ko:K02821,ko:K03483 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 COG3711 Transcriptional antiterminator
HHEMLNNI_03630 6.86e-235 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HHEMLNNI_03631 4.64e-151 XK27_07680 - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HHEMLNNI_03632 2.48e-118 - - - K - - - Bacterial regulatory proteins, tetR family
HHEMLNNI_03633 2.28e-223 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
HHEMLNNI_03634 2.33e-23 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
HHEMLNNI_03635 5.8e-219 - - - K - - - LysR substrate binding domain
HHEMLNNI_03636 8.48e-241 dapB 1.4.1.12, 1.4.1.26 - S ko:K21672 ko00310,ko00330,ko00472,map00310,map00330,map00472 ko00000,ko00001,ko01000 Dihydrodipicolinate reductase, N-terminus
HHEMLNNI_03637 1.4e-314 - - - C - - - Na+/H+ antiporter family
HHEMLNNI_03638 1.01e-100 - - - S - - - glyoxalase bleomycin resistance protein dioxygenase
HHEMLNNI_03639 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HHEMLNNI_03640 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HHEMLNNI_03641 3.15e-277 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HHEMLNNI_03642 1.08e-220 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HHEMLNNI_03643 1.01e-129 - - - CO - - - Thioredoxin
HHEMLNNI_03644 1.77e-235 yvnB - - Q - - - Calcineurin-like phosphoesterase
HHEMLNNI_03646 1.15e-12 - - - - - - - -
HHEMLNNI_03647 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HHEMLNNI_03648 1.6e-138 yfhC - - C - - - nitroreductase
HHEMLNNI_03649 6.48e-152 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HHEMLNNI_03650 2.98e-82 - - - S - - - Bacteriophage holin family
HHEMLNNI_03651 1.84e-30 - - - - - - - -
HHEMLNNI_03652 0.0 - - - L - - - Phage minor structural protein
HHEMLNNI_03653 8.07e-174 - - - S - - - Phage tail protein
HHEMLNNI_03654 1.16e-74 - - - D - - - Phage tail tape measure protein, TP901 family
HHEMLNNI_03655 4.08e-101 - - - - - - - -
HHEMLNNI_03656 3.02e-92 - - - - - - - -
HHEMLNNI_03657 1.83e-193 - - - S - - - Short C-terminal domain
HHEMLNNI_03658 4.48e-273 - 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HHEMLNNI_03659 3.83e-312 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HHEMLNNI_03660 1.43e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HHEMLNNI_03661 0.0 malK 2.7.13.3 - T ko:K02476,ko:K11614,ko:K11637 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HHEMLNNI_03662 1.06e-96 - - - M - - - ArpU family transcriptional regulator
HHEMLNNI_03663 2.4e-192 - 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HHEMLNNI_03664 8e-154 - - - E ko:K02029,ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03665 3.11e-145 - - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03666 6.61e-192 tcyA_1 - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HHEMLNNI_03667 1.8e-185 - - - - - - - -
HHEMLNNI_03668 7.72e-197 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HHEMLNNI_03669 2.7e-232 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HHEMLNNI_03670 2.15e-92 - - - S - - - GtrA-like protein
HHEMLNNI_03671 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HHEMLNNI_03672 6.31e-11 - - - - - - - -
HHEMLNNI_03673 4.31e-11 - - - - - - - -
HHEMLNNI_03674 2.16e-114 - - - S - - - Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HHEMLNNI_03675 1.01e-176 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HHEMLNNI_03676 7.47e-141 yjgD - - S - - - Protein of unknown function (DUF1641)
HHEMLNNI_03677 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HHEMLNNI_03678 7.57e-184 nirC - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HHEMLNNI_03679 2.38e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HHEMLNNI_03680 2.79e-97 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HHEMLNNI_03681 5.32e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HHEMLNNI_03682 3.23e-307 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HHEMLNNI_03683 1.3e-240 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HHEMLNNI_03684 1.37e-109 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HHEMLNNI_03685 6.79e-135 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HHEMLNNI_03686 6.25e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HHEMLNNI_03687 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
HHEMLNNI_03688 2.72e-195 - 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHEMLNNI_03689 1.75e-158 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HHEMLNNI_03690 1.27e-169 - - - S - - - carbohydrate derivative metabolic process
HHEMLNNI_03691 3.06e-283 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system ascorbate-specific transporter subunit IIC
HHEMLNNI_03692 5.5e-56 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG3414 Phosphotransferase system, galactitol-specific IIB component
HHEMLNNI_03693 2.88e-96 - 2.7.1.194 - GT ko:K02821,ko:K03483 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHEMLNNI_03694 0.0 - - - G - - - Mga helix-turn-helix domain
HHEMLNNI_03695 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHEMLNNI_03696 7.46e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHEMLNNI_03697 1.35e-152 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HHEMLNNI_03699 3.18e-261 gldA - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
HHEMLNNI_03700 1.57e-194 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
HHEMLNNI_03701 1.37e-143 metP_2 - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HHEMLNNI_03702 1.06e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHEMLNNI_03703 2.86e-179 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHEMLNNI_03704 7.3e-34 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HHEMLNNI_03705 1.24e-145 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHEMLNNI_03706 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HHEMLNNI_03707 1.18e-230 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHEMLNNI_03708 2.21e-114 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HHEMLNNI_03709 1.44e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HHEMLNNI_03710 3.85e-108 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HHEMLNNI_03711 1.11e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HHEMLNNI_03714 1.28e-274 - 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HHEMLNNI_03715 1.93e-77 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHEMLNNI_03716 2.93e-85 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHEMLNNI_03717 8.89e-156 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HHEMLNNI_03734 6.89e-178 yobO - - M - - - Pectate lyase superfamily protein
HHEMLNNI_03735 6.37e-284 yobO - - M - - - Pectate lyase superfamily protein
HHEMLNNI_03737 6.43e-48 - - - S - - - Protein of unknown function (DUF3021)
HHEMLNNI_03738 9.22e-63 - - - K - - - Transcriptional regulator C-terminal region
HHEMLNNI_03739 3.32e-66 - - - K - - - Helix-turn-helix domain
HHEMLNNI_03740 1.07e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
HHEMLNNI_03741 0.0 yhjG - - CH - - - FAD binding domain
HHEMLNNI_03742 5.57e-86 - - - J - - - oxidation-reduction process
HHEMLNNI_03743 4.83e-108 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HHEMLNNI_03744 2.94e-217 - - - S - - - thiolester hydrolase activity
HHEMLNNI_03745 2.75e-291 - 3.3.2.9 - S ko:K01253 ko00980,ko04976,ko05204,map00980,map04976,map05204 ko00000,ko00001,ko01000,ko01002 Epoxide hydrolase N terminus
HHEMLNNI_03746 3.92e-308 nox 1.11.1.1 - P ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HHEMLNNI_03747 1.85e-141 - - - K - - - Bacterial transcriptional repressor C-terminal
HHEMLNNI_03749 2.6e-44 - - - M - - - Host cell surface-exposed lipoprotein
HHEMLNNI_03750 3.05e-121 - - - F - - - uridine kinase
HHEMLNNI_03751 3.64e-179 - - - K - - - helix_turn_helix, mercury resistance
HHEMLNNI_03752 0.0 pbpE - - V - - - Beta-lactamase
HHEMLNNI_03753 8.96e-59 ykvN - - K - - - HxlR-like helix-turn-helix
HHEMLNNI_03754 2.07e-43 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HHEMLNNI_03755 8.76e-261 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HHEMLNNI_03756 9.22e-211 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_03757 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HHEMLNNI_03758 0.0 - - - K - - - Mga helix-turn-helix domain
HHEMLNNI_03759 3.04e-278 - 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 amidohydrolase
HHEMLNNI_03760 1.88e-67 - - - S - - - PRD domain
HHEMLNNI_03761 2.29e-80 - - - S - - - Glycine-rich SFCGS
HHEMLNNI_03762 3.68e-77 - - - S - - - Domain of unknown function (DUF4312)
HHEMLNNI_03763 9.36e-179 - - - S - - - Domain of unknown function (DUF4311)
HHEMLNNI_03764 4.08e-146 - - - S - - - Domain of unknown function (DUF4310)
HHEMLNNI_03765 8.41e-260 selA 2.9.1.1 - E ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
HHEMLNNI_03766 9.27e-159 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
HHEMLNNI_03767 0.000396 yhfA - - S - - - phosphonoacetaldehyde hydrolase activity
HHEMLNNI_03768 3.52e-66 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HHEMLNNI_03769 2.49e-269 - - - L ko:K07012 - ko00000,ko01000,ko02048 Metal dependent phosphohydrolases with conserved 'HD' motif.
HHEMLNNI_03770 1.23e-116 cas5 - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein
HHEMLNNI_03771 2.86e-227 csd1 - - M ko:K19117 - ko00000,ko02048 CRISPR-associated protein (Cas_Csd1)
HHEMLNNI_03772 1.61e-144 csd2 - - L ko:K19115,ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
HHEMLNNI_03773 1.56e-93 cas4 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 RecB family exonuclease
HHEMLNNI_03774 5.6e-145 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHEMLNNI_03775 4.42e-43 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHEMLNNI_03776 4.4e-23 - - - G ko:K09973 - ko00000 PFAM GumN family protein
HHEMLNNI_03777 3.25e-46 - - - G ko:K09973 - ko00000 PFAM GumN family protein
HHEMLNNI_03778 2.61e-235 pld1 1.1.1.122 - C ko:K00064 ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Aldo/keto reductase family
HHEMLNNI_03779 2.52e-91 - - - H - - - RibD C-terminal domain
HHEMLNNI_03780 1.63e-75 - - - S - - - YjbR
HHEMLNNI_03781 1.47e-91 - - - S - - - Glyoxalase-like domain
HHEMLNNI_03782 9.18e-188 - - - K - - - helix_turn_helix, arabinose operon control protein
HHEMLNNI_03783 3.69e-124 - - - K - - - Winged helix DNA-binding domain
HHEMLNNI_03784 9.49e-197 - 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HHEMLNNI_03785 1.89e-225 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
HHEMLNNI_03786 1.04e-76 ydzF - - K - - - HxlR-like helix-turn-helix
HHEMLNNI_03787 1.72e-305 serS3 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHEMLNNI_03788 1.14e-167 - - - L - - - DNA alkylation repair enzyme
HHEMLNNI_03789 6.58e-24 - - - S - - - AAA domain
HHEMLNNI_03790 2.94e-122 - 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
HHEMLNNI_03792 1.64e-244 - - - T - - - Signal transduction histidine kinase
HHEMLNNI_03793 5.87e-139 - - - KT - - - LuxR family transcriptional regulator
HHEMLNNI_03794 1.47e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HHEMLNNI_03795 1.33e-277 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HHEMLNNI_03796 3.19e-229 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HHEMLNNI_03797 4.18e-198 gspA - - M - - - Glycosyl transferase family 8
HHEMLNNI_03798 1.34e-91 yxjI - - S - - - LURP-one-related
HHEMLNNI_03799 9.42e-225 adcA - - P ko:K09815,ko:K09818 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HHEMLNNI_03800 1.83e-168 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HHEMLNNI_03802 2.68e-129 - - - M - - - Peptidoglycan-binding domain 1 protein
HHEMLNNI_03803 1.4e-127 p20 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HHEMLNNI_03804 2.2e-62 - - - - - - - -
HHEMLNNI_03805 2.84e-137 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHEMLNNI_03806 0.0 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
HHEMLNNI_03807 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K06931,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HHEMLNNI_03808 7.17e-74 - - - S - - - Regulatory protein YrvL
HHEMLNNI_03809 7.86e-242 yccF - - K ko:K07039 - ko00000 SEC-C motif
HHEMLNNI_03810 0.0 - - - P ko:K14445 - ko00000,ko02000 Sodium:sulfate symporter transmembrane region
HHEMLNNI_03811 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HHEMLNNI_03812 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HHEMLNNI_03813 2.45e-124 - - - - - - - -
HHEMLNNI_03814 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHEMLNNI_03815 0.0 scrA5 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_03816 0.0 bglC1 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HHEMLNNI_03817 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HHEMLNNI_03818 3.15e-195 - - - K - - - helix_turn_helix, arabinose operon control protein
HHEMLNNI_03819 1.36e-121 - - - S - - - MepB protein
HHEMLNNI_03820 2.75e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_03821 8.23e-169 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HHEMLNNI_03822 1.55e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_03823 3.38e-158 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HHEMLNNI_03824 1e-167 - - - - - - - -
HHEMLNNI_03825 6.84e-253 yhfE - - G - - - peptidase M42
HHEMLNNI_03826 6.41e-106 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HHEMLNNI_03827 2.68e-129 yhzB - - S - - - B3/4 domain
HHEMLNNI_03828 1.91e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HHEMLNNI_03829 9.84e-123 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHEMLNNI_03830 6.67e-108 - - - K - - - Acetyltransferase (GNAT) domain
HHEMLNNI_03831 1.59e-213 yhbB - - S - - - Putative amidase domain
HHEMLNNI_03832 7.16e-114 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHEMLNNI_03833 3.08e-115 yufK - - S - - - Family of unknown function (DUF5366)
HHEMLNNI_03834 1.17e-71 - 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HHEMLNNI_03835 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HHEMLNNI_03836 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HHEMLNNI_03837 2.19e-135 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HHEMLNNI_03838 1.69e-179 cysA1 - - S - - - AAA domain
HHEMLNNI_03839 1.11e-281 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HHEMLNNI_03841 3.59e-212 - - - K - - - Bacterial regulatory proteins, tetR family
HHEMLNNI_03842 0.0 - - - EGP - - - the major facilitator superfamily
HHEMLNNI_03843 1.54e-222 - - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HHEMLNNI_03844 3.14e-191 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
HHEMLNNI_03846 1.9e-109 - - - S - - - Protein of unknown function (DUF664)
HHEMLNNI_03847 0.0 - - - G ko:K10297 - ko00000,ko04121 Right handed beta helix region
HHEMLNNI_03848 3.19e-205 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_03849 0.0 - - - E ko:K03307 - ko00000 Sodium:solute symporter family
HHEMLNNI_03850 3.83e-165 - - - K ko:K03710 - ko00000,ko03000 UTRA
HHEMLNNI_03851 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HHEMLNNI_03852 1.97e-170 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HHEMLNNI_03853 1.12e-288 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHEMLNNI_03854 6.62e-177 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHEMLNNI_03855 1.34e-168 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HHEMLNNI_03856 8.16e-288 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HHEMLNNI_03857 8.12e-151 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
HHEMLNNI_03858 2.31e-175 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HHEMLNNI_03859 1.02e-93 - - - - - - - -
HHEMLNNI_03861 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHEMLNNI_03862 8.66e-161 sfsA - - S ko:K06206 - ko00000 Sugar fermentation stimulation protein
HHEMLNNI_03863 0.0 - 1.1.5.3 - C ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
HHEMLNNI_03864 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HHEMLNNI_03865 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HHEMLNNI_03866 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HHEMLNNI_03867 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HHEMLNNI_03868 2.59e-295 avtA - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHEMLNNI_03869 4.1e-193 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Peptidase family M48
HHEMLNNI_03870 3.52e-124 lemA - - S ko:K03744 - ko00000 LemA family
HHEMLNNI_03871 1.97e-275 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HHEMLNNI_03872 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HHEMLNNI_03873 1.95e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HHEMLNNI_03874 4.36e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HHEMLNNI_03875 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HHEMLNNI_03877 4.32e-278 - - - - - - - -
HHEMLNNI_03878 1.78e-102 - - - K ko:K03088 - ko00000,ko03021 Sigma-70, region 4
HHEMLNNI_03879 8.44e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_03880 9.53e-206 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HHEMLNNI_03881 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_03882 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_03883 7.35e-291 - - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
HHEMLNNI_03884 4.06e-220 - - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03885 7.53e-206 ytcP1 - - U ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_03886 1.14e-52 - - - - - - - -
HHEMLNNI_03887 7.3e-131 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HHEMLNNI_03888 1.07e-142 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
HHEMLNNI_03889 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HHEMLNNI_03890 8.57e-217 - - - K - - - AraC-like ligand binding domain
HHEMLNNI_03891 7.66e-251 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HHEMLNNI_03892 2.25e-263 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_03893 2.08e-138 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHEMLNNI_03894 3.13e-282 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HHEMLNNI_03895 1.03e-97 - - - K ko:K15973 - ko00000,ko03000 transcriptional
HHEMLNNI_03896 2.33e-74 - - - - - - - -
HHEMLNNI_03897 2.17e-118 - 3.1.1.29 - K ko:K01056 - ko00000,ko01000,ko03012 -acetyltransferase
HHEMLNNI_03898 1.18e-311 - - - EK - - - Alanine-glyoxylate amino-transferase
HHEMLNNI_03899 1.16e-107 yvbK - - K - - - acetyltransferase
HHEMLNNI_03900 3.43e-187 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HHEMLNNI_03901 4.21e-105 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHEMLNNI_03902 2.97e-267 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HHEMLNNI_03903 3.84e-257 - - - KT ko:K02647 - ko00000,ko03000 Sugar diacid utilization regulator
HHEMLNNI_03904 4.81e-252 yetN - - S - - - Protein of unknown function (DUF3900)
HHEMLNNI_03905 2.61e-165 - - - - - - - -
HHEMLNNI_03906 3.31e-150 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHEMLNNI_03907 2.08e-240 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HHEMLNNI_03908 2.25e-200 hisJ3 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 PHP domain
HHEMLNNI_03909 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HHEMLNNI_03910 3.7e-123 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HHEMLNNI_03911 4.31e-166 - - - - ko:K06336 - ko00000,ko01002 -
HHEMLNNI_03912 4.68e-126 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
HHEMLNNI_03913 1.35e-169 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HHEMLNNI_03914 1.8e-226 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HHEMLNNI_03915 2.37e-181 - - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HHEMLNNI_03916 6.83e-224 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HHEMLNNI_03917 3.03e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHEMLNNI_03919 2.91e-256 aprE 3.4.21.62 - O ko:K01342 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HHEMLNNI_03920 1.91e-299 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
HHEMLNNI_03921 2.26e-147 cwlK - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
HHEMLNNI_03922 0.0 - - - E ko:K03294,ko:K14052 - ko00000,ko02000 Amino acid permease
HHEMLNNI_03923 7.88e-208 sseA 2.8.1.1, 2.8.1.2 - P ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 ko00000,ko00001,ko01000 sulfurtransferase
HHEMLNNI_03924 1.14e-294 yukF - - QT - - - Transcriptional regulator
HHEMLNNI_03925 3.15e-257 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HHEMLNNI_03926 1.68e-257 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HHEMLNNI_03927 2.05e-203 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HHEMLNNI_03928 3.02e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HHEMLNNI_03929 5.66e-191 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HHEMLNNI_03930 4.65e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHEMLNNI_03931 8.58e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHEMLNNI_03932 4.34e-203 - - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
HHEMLNNI_03933 1.7e-299 - 2.7.13.3 - T ko:K07706,ko:K07717 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase-like ATPases
HHEMLNNI_03934 5.06e-194 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HHEMLNNI_03935 2.82e-208 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_03936 1e-220 dppC - - EP ko:K16201 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_03937 3.3e-235 dppD - - P ko:K02031,ko:K16202 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_03938 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HHEMLNNI_03939 4.47e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HHEMLNNI_03940 5.84e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HHEMLNNI_03941 1.84e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_03942 4.14e-79 hxlR - - K - - - transcriptional
HHEMLNNI_03943 5.35e-145 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HHEMLNNI_03944 6.16e-168 - - - T - - - Universal stress protein family
HHEMLNNI_03945 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HHEMLNNI_03946 5.88e-89 mnhB2 - - P ko:K05566 - ko00000,ko02000 antiporter activity
HHEMLNNI_03947 1.85e-66 mnhC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHEMLNNI_03948 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHEMLNNI_03949 2.82e-111 mnhE2 - - P ko:K05569 - ko00000,ko02000 Na+/H+ ion antiporter subunit
HHEMLNNI_03950 2.23e-51 mnhF2 - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHEMLNNI_03951 4.62e-79 - - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HHEMLNNI_03952 3.61e-208 - - - S - - - electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
HHEMLNNI_03953 2.55e-248 - - - G - - - Xylose isomerase
HHEMLNNI_03954 2.66e-248 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HHEMLNNI_03955 1.69e-179 - - - G - - - Xylose isomerase-like TIM barrel
HHEMLNNI_03956 2.5e-279 - - - S ko:K09927 - ko00000 Winged helix DNA-binding domain
HHEMLNNI_03957 2.6e-142 - - - S - - - Integral membrane protein
HHEMLNNI_03958 5.02e-63 - - - - - - - -
HHEMLNNI_03959 7.76e-182 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HHEMLNNI_03960 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HHEMLNNI_03961 8.21e-132 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHEMLNNI_03962 4.11e-174 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HHEMLNNI_03963 9.81e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHEMLNNI_03964 3.58e-239 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HHEMLNNI_03965 4.12e-294 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHEMLNNI_03966 4.38e-35 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HHEMLNNI_03967 1.53e-74 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HHEMLNNI_03968 1.32e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HHEMLNNI_03969 5.44e-70 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HHEMLNNI_03970 3.52e-96 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HHEMLNNI_03971 1.25e-238 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HHEMLNNI_03972 8.36e-72 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HHEMLNNI_03973 9.7e-109 rsbW 2.7.11.1 - T ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HHEMLNNI_03974 1.49e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHEMLNNI_03975 1.11e-151 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HHEMLNNI_03976 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HHEMLNNI_03977 3.43e-13 - - - - - - - -
HHEMLNNI_03978 1.99e-114 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HHEMLNNI_03986 1.65e-23 - - - K - - - transcriptional regulator
HHEMLNNI_03987 0.0 - - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HHEMLNNI_03988 3e-121 yokH - - G - - - SMI1 / KNR4 family
HHEMLNNI_03989 1.62e-60 - - - KQ - - - helix_turn_helix, mercury resistance
HHEMLNNI_03990 2.53e-127 yrkC - - G - - - Cupin domain
HHEMLNNI_03991 6.34e-183 - - - S - - - TraX protein
HHEMLNNI_03992 8.23e-218 mviM3 - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
HHEMLNNI_03993 7.28e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HHEMLNNI_03994 1.2e-101 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HHEMLNNI_03995 2.84e-72 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HHEMLNNI_03996 4.43e-291 ydfA - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHEMLNNI_03999 4.15e-304 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HHEMLNNI_04001 1.54e-215 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HHEMLNNI_04002 9.03e-153 ydhC - - K - - - FCD
HHEMLNNI_04003 8.34e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HHEMLNNI_04004 2.4e-86 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHEMLNNI_04005 2.79e-256 - - - K - - - ArsR family transcriptional regulator
HHEMLNNI_04006 5.32e-285 - - - EGP - - - Transmembrane secretion effector
HHEMLNNI_04007 1.23e-166 - - - C - - - Oxidoreductase NAD-binding domain
HHEMLNNI_04008 0.0 - - - L - - - ABC transporter
HHEMLNNI_04009 4.42e-96 - - - K - - - Activator of Hsp90 ATPase homolog 1-like protein
HHEMLNNI_04010 5.22e-75 - - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HHEMLNNI_04011 2.54e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HHEMLNNI_04012 1.4e-65 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
HHEMLNNI_04013 1.13e-159 azlC - - E - - - AzlC protein
HHEMLNNI_04014 3.25e-97 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHEMLNNI_04015 2.77e-94 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
HHEMLNNI_04016 6.17e-300 - - - F - - - Belongs to the Nudix hydrolase family
HHEMLNNI_04017 1.67e-86 - - - J - - - L-PSP family endoribonuclease
HHEMLNNI_04018 0.0 - - - K ko:K03491 - ko00000,ko03000 transcriptional regulator, MtlR
HHEMLNNI_04019 5.07e-202 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HHEMLNNI_04020 0.0 - 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HHEMLNNI_04021 6.26e-214 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HHEMLNNI_04022 4.42e-128 - - - - - - - -
HHEMLNNI_04024 2.57e-36 - - - - - - - -
HHEMLNNI_04029 1.87e-76 ygzB - - S - - - UPF0295 protein
HHEMLNNI_04030 1.18e-103 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HHEMLNNI_04031 6.47e-64 - - - S - - - Cyclic-di-AMP receptor
HHEMLNNI_04032 6.64e-232 ghrA - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHEMLNNI_04033 4.85e-116 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HHEMLNNI_04034 5.04e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HHEMLNNI_04035 3.87e-241 ygaE - - S - - - Membrane
HHEMLNNI_04036 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HHEMLNNI_04037 2.94e-133 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HHEMLNNI_04038 6.03e-23 - - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HHEMLNNI_04039 3.78e-168 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_04040 5.62e-27 yfhS - - - - - - -
HHEMLNNI_04041 3.18e-77 - - - - - - - -
HHEMLNNI_04042 2.28e-169 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHEMLNNI_04043 2.26e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HHEMLNNI_04044 5.96e-240 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HHEMLNNI_04046 9.25e-30 - - - S - - - YpzG-like protein
HHEMLNNI_04047 9.17e-70 yfhH - - S - - - Protein of unknown function (DUF1811)
HHEMLNNI_04048 9.64e-183 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HHEMLNNI_04049 1.43e-218 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HHEMLNNI_04050 4.73e-66 - - - - - - - -
HHEMLNNI_04051 1.39e-259 mccF - - V - - - LD-carboxypeptidase
HHEMLNNI_04052 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHEMLNNI_04053 2.29e-81 - - - - - - - -
HHEMLNNI_04055 2.51e-94 - - - K - - - Transcriptional regulator
HHEMLNNI_04056 1.6e-214 - - - O - - - Pyridine nucleotide-disulphide oxidoreductase
HHEMLNNI_04057 6.41e-190 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HHEMLNNI_04058 7.39e-187 - - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
HHEMLNNI_04059 0.0 - - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HHEMLNNI_04060 8.1e-153 - - - G ko:K15640 - ko00000 Belongs to the phosphoglycerate mutase family
HHEMLNNI_04061 4.13e-280 yfkA - - S - - - YfkB-like domain
HHEMLNNI_04062 1.97e-188 yfkD - - S - - - YfkD-like protein
HHEMLNNI_04065 1.21e-29 - - - S - - - Fur-regulated basic protein B
HHEMLNNI_04066 5.9e-314 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HHEMLNNI_04067 2.96e-241 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HHEMLNNI_04068 1.75e-186 - - - - - - - -
HHEMLNNI_04069 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HHEMLNNI_04070 0.0 kat 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HHEMLNNI_04071 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
HHEMLNNI_04072 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HHEMLNNI_04073 1.21e-146 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Caulimovirus viroplasmin
HHEMLNNI_04074 1.49e-53 - - - - - - - -
HHEMLNNI_04075 2.17e-62 - - - K - - - SpoVT / AbrB like domain
HHEMLNNI_04076 2.07e-75 - - - - - - - -
HHEMLNNI_04077 1.61e-307 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHEMLNNI_04078 3.04e-233 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HHEMLNNI_04079 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HHEMLNNI_04080 1.35e-210 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HHEMLNNI_04081 2.57e-173 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HHEMLNNI_04082 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHEMLNNI_04083 3.48e-269 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HHEMLNNI_04084 2.29e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HHEMLNNI_04085 5.63e-164 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HHEMLNNI_04086 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HHEMLNNI_04087 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HHEMLNNI_04088 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HHEMLNNI_04089 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HHEMLNNI_04090 2.84e-300 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHEMLNNI_04091 2.72e-314 alsT - - E ko:K03310 - ko00000 Sodium alanine symporter
HHEMLNNI_04092 2.04e-122 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HHEMLNNI_04093 0.0 glpD 1.1.5.3 - C ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HHEMLNNI_04094 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHEMLNNI_04095 2.52e-298 kinB3 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_04096 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HHEMLNNI_04097 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HHEMLNNI_04098 0.0 uvrD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HHEMLNNI_04099 1.48e-217 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HHEMLNNI_04100 3.79e-181 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HHEMLNNI_04101 1.22e-175 phnE - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHEMLNNI_04102 3.66e-184 ptxC - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHEMLNNI_04103 2.05e-185 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHEMLNNI_04104 6.87e-311 - - - V - - - MatE
HHEMLNNI_04105 2.01e-139 - - - K - - - Bacterial regulatory proteins, tetR family
HHEMLNNI_04106 2.64e-208 pepI 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha/beta hydrolase family
HHEMLNNI_04107 4.88e-207 dppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_04108 3.99e-233 dppB - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHEMLNNI_04109 0.0 hbpA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HHEMLNNI_04110 2e-241 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_04111 8.09e-235 dppD - - P ko:K02031,ko:K16202 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HHEMLNNI_04112 0.0 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
HHEMLNNI_04113 2.46e-85 - - - S - - - Domain of unknown function (DUF4440)
HHEMLNNI_04114 1.11e-133 ynaD - - J - - - Acetyltransferase (GNAT) domain
HHEMLNNI_04115 4.47e-294 - - - S ko:K07112 - ko00000 Sulphur transport
HHEMLNNI_04116 1.05e-225 - - - S ko:K01989 - ko00000,ko00002,ko02000 transport system, periplasmic component
HHEMLNNI_04117 1.99e-218 - - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HHEMLNNI_04118 1.74e-181 - - - S ko:K05833 - ko00000,ko00002,ko02000 transport system, ATPase component
HHEMLNNI_04119 2.21e-247 - - - - - - - -
HHEMLNNI_04120 9.37e-255 cysA 3.6.3.25 - P ko:K02045 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HHEMLNNI_04121 2.72e-172 cysW - - P ko:K02047 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG4208 ABC-type sulfate transport system, permease component
HHEMLNNI_04122 3.57e-174 cysT - - O ko:K02046 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0555 ABC-type sulfate transport system, permease component
HHEMLNNI_04123 4.61e-251 sbp - - P ko:K02048 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG1613 ABC-type sulfate transport system, periplasmic component
HHEMLNNI_04124 1.62e-106 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHEMLNNI_04125 0.0 - - - T - - - COG0642 Signal transduction histidine kinase
HHEMLNNI_04126 0.0 dld 1.1.2.4, 1.1.3.15 - C ko:K00102,ko:K00104 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HHEMLNNI_04127 1.05e-206 yocS - - S ko:K03453 - ko00000 -transporter
HHEMLNNI_04128 8.24e-183 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHEMLNNI_04129 1.2e-207 - 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HHEMLNNI_04130 2.94e-71 tagD 2.7.7.39 - H ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HHEMLNNI_04131 4.68e-304 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHEMLNNI_04132 8.59e-205 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHEMLNNI_04133 5.06e-89 - - - I - - - CDP-alcohol phosphatidyltransferase
HHEMLNNI_04134 2.3e-185 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HHEMLNNI_04135 0.0 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HHEMLNNI_04136 1.18e-254 - - - M - - - Glycosyltransferase like family 2
HHEMLNNI_04137 4.82e-179 - - - E - - - lipolytic protein G-D-S-L family
HHEMLNNI_04138 2.08e-85 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HHEMLNNI_04139 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHEMLNNI_04140 1.08e-246 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHEMLNNI_04141 8.45e-147 ymaB - - S - - - MutT family
HHEMLNNI_04142 1.06e-129 pncA - - Q - - - COG1335 Amidases related to nicotinamidase
HHEMLNNI_04143 2.24e-37 - - - - - - - -
HHEMLNNI_04144 9.52e-285 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HHEMLNNI_04145 4.11e-173 fabG9 - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HHEMLNNI_04146 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HHEMLNNI_04147 0.0 - 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 invertase
HHEMLNNI_04148 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_04149 4.03e-207 lplC7 - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HHEMLNNI_04150 1.43e-225 - - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HHEMLNNI_04152 3.43e-236 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
HHEMLNNI_04154 2.18e-148 - - - - - - - -
HHEMLNNI_04155 4e-259 - - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HHEMLNNI_04156 1.45e-202 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_04157 4.36e-209 - - - G ko:K02025,ko:K17238 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HHEMLNNI_04158 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HHEMLNNI_04159 0.0 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HHEMLNNI_04160 6.15e-70 - - - K - - - sequence-specific DNA binding
HHEMLNNI_04161 1.85e-204 - - - S - - - NYN domain
HHEMLNNI_04162 5.47e-173 - - - - - - - -
HHEMLNNI_04164 2.15e-82 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HHEMLNNI_04165 8.03e-160 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HHEMLNNI_04166 1.73e-180 - - - - - - - -
HHEMLNNI_04168 1.39e-142 - 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HHEMLNNI_04169 9.84e-181 - - - S - - - Metallo-beta-lactamase superfamily
HHEMLNNI_04170 1.71e-111 - - - K - - - Transcriptional regulator
HHEMLNNI_04171 6.92e-193 yrzF - - KLT - - - serine threonine protein kinase
HHEMLNNI_04172 1.59e-53 - - - - - - - -
HHEMLNNI_04173 1.04e-269 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HHEMLNNI_04174 6.37e-152 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHEMLNNI_04176 3.46e-242 - 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHEMLNNI_04177 7.4e-165 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HHEMLNNI_04178 2.57e-133 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HHEMLNNI_04179 3.61e-214 yobV - - K - - - WYL domain
HHEMLNNI_04180 2.65e-118 dinB - - S - - - DinB family
HHEMLNNI_04181 1.2e-196 yxeH - - S - - - hydrolases of the HAD superfamily
HHEMLNNI_04182 1.01e-222 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHEMLNNI_04183 5.16e-272 - 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HHEMLNNI_04184 1.01e-224 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HHEMLNNI_04185 1.7e-148 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
HHEMLNNI_04186 3.15e-120 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHEMLNNI_04187 6.63e-55 - - - - - - - -
HHEMLNNI_04201 1.08e-310 - - - UW ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HHEMLNNI_04207 8.63e-226 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HHEMLNNI_04208 3.13e-236 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HHEMLNNI_04209 6.65e-183 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HHEMLNNI_04210 1.21e-90 - - - - - - - -
HHEMLNNI_04211 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHEMLNNI_04212 9.85e-316 - - - M - - - -O-antigen
HHEMLNNI_04213 4.83e-72 - - - - - - - -
HHEMLNNI_04214 8.43e-261 - - - M - - - Glycosyl transferases group 1
HHEMLNNI_04215 1.02e-194 - - - S - - - Glycosyl transferase family 2
HHEMLNNI_04216 0.0 - - - S - - - Polysaccharide biosynthesis protein
HHEMLNNI_04217 9.45e-152 - - - K - - - Transcriptional regulator
HHEMLNNI_04218 6.2e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Iron/manganese superoxide dismutases, C-terminal domain
HHEMLNNI_04219 4.67e-52 - - - S - - - Protein of unknown function (DUF1450)
HHEMLNNI_04220 8.99e-42 - - - C - - - 4Fe-4S binding domain
HHEMLNNI_04221 3.13e-314 - - - S ko:K12940 - ko00000,ko01002 Peptidase dimerisation domain
HHEMLNNI_04222 0.0 - - - H ko:K12942 - ko00000 AbgT putative transporter family
HHEMLNNI_04223 0.0 - - - S ko:K12941,ko:K21613 - ko00000,ko01000,ko01002 amidohydrolase
HHEMLNNI_04224 5.38e-309 - - - KT - - - transcriptional regulatory protein
HHEMLNNI_04225 5.49e-193 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HHEMLNNI_04226 1.94e-270 thrCA 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HHEMLNNI_04227 1.87e-108 - - - M ko:K01993 - ko00000 PFAM secretion protein HlyD family protein
HHEMLNNI_04228 9.79e-184 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HHEMLNNI_04229 1.27e-254 ybhR - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HHEMLNNI_04230 7.35e-150 ycfA - - K - - - Transcriptional regulator
HHEMLNNI_04231 1.05e-135 ywqN_1 - - S - - - NAD(P)H-dependent
HHEMLNNI_04232 7.56e-209 - - - K - - - LysR substrate binding domain
HHEMLNNI_04233 1.26e-10 tlp - - S ko:K06434 - ko00000 spore protein
HHEMLNNI_04236 1.04e-110 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
HHEMLNNI_04237 2.3e-53 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)